dbPTM

ZFR_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZFR_HUMAN
UniProt AC	Q96KR1
Protein Name	Zinc finger RNA-binding protein
Gene Name	ZFR
Organism	Homo sapiens (Human).
Sequence Length	1074
Subcellular Localization	Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome. Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules (By similarity)..
Protein Description	Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA (By similarity)..
Protein Sequence	MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAAAAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHTATDYGYTQRQQEAPPPPPPATTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAETYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTAVTYSGTSYSGYEAAVYSAASSYYQQQQQQQKQAAAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQNTSSSNSSTRGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQATSSTAVSASKPTASPSSIAANNCTVNTSSVATSSMKGLTTTGNSSLNSTSNTKVSAVPTNMAAKKTSTPKINFVGGNKLQSTGNKAEDIKGTECVKSTPVTSAVQIPEVKQDTVSEPVTPASLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQHHWDDRRRMPDGGYPHGPPGPLGLLGVRPGMPPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEKNKNKEGDDKKEGGKDRALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKTLLSRIAENLPKQLAVISPEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMSQRFNIHNNRKRRRDSDGVDGFEAEGKKDKKDYDNF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	IPICPVVSFTYVPSR CCCCCEEEEEEECCC	16.47	20068231
11	Phosphorylation	ICPVVSFTYVPSRLG CCCEEEEEEECCCCC	18.99	20068231
12	Phosphorylation	CPVVSFTYVPSRLGE CCEEEEEEECCCCCC	14.35	20068231
15	Phosphorylation	VSFTYVPSRLGEDAK EEEEEECCCCCCCCC	30.05	20068231
25	O-linked_Glycosylation	GEDAKMATGNYFGFT CCCCCCCCCCCCCCC	23.59	32574038
46	O-linked_Glycosylation	AAAAAQYSQQPASGV HHHHHHHCCCCCCCC	15.40	32574038
51	O-linked_Glycosylation	QYSQQPASGVAYSHP HHCCCCCCCCCCCCC	40.25	32574038
56	O-linked_Glycosylation	PASGVAYSHPTTVAS CCCCCCCCCCCEEEE	17.16	32574038
59	O-linked_Glycosylation	GVAYSHPTTVASYTV CCCCCCCCEEEEEEE	28.60	32574038
60	O-linked_Glycosylation	VAYSHPTTVASYTVH CCCCCCCEEEEEEEE	20.65	32574038
63	O-linked_Glycosylation	SHPTTVASYTVHQAP CCCCEEEEEEEECCC	19.59	32574038
65	O-linked_Glycosylation	PTTVASYTVHQAPVA CCEEEEEEEECCCCC	14.71	32574038
75	O-linked_Glycosylation	QAPVAAHTVTAAYAP CCCCCCEEEEEECCC	18.15	32574038
77	O-linked_Glycosylation	PVAAHTVTAAYAPAA CCCCEEEEEECCCHH	13.51	32574038
86	O-linked_Glycosylation	AYAPAAATVAVARPA ECCCHHHEEECCCCH	12.31	32574038
102	O-linked_Glycosylation	VAVAAAATAAAYGGY HHHHHHHHHHHHCCC	16.47	32574038
102	Phosphorylation	VAVAAAATAAAYGGY HHHHHHHHHHHHCCC	16.47	29978859
106	Phosphorylation	AAATAAAYGGYPTAH HHHHHHHHCCCCCCC	13.32	29978859
109	Phosphorylation	TAAAYGGYPTAHTAT HHHHHCCCCCCCCCC	7.95	29978859
111	Phosphorylation	AAYGGYPTAHTATDY HHHCCCCCCCCCCCC	23.69	29978859
114	O-linked_Glycosylation	GGYPTAHTATDYGYT CCCCCCCCCCCCCCC	28.87	32574038
114	Phosphorylation	GGYPTAHTATDYGYT CCCCCCCCCCCCCCC	28.87	29978859
116	Phosphorylation	YPTAHTATDYGYTQR CCCCCCCCCCCCCCC	30.80	29978859
118	Phosphorylation	TAHTATDYGYTQRQQ CCCCCCCCCCCCCCC	14.00	25884760
120	Phosphorylation	HTATDYGYTQRQQEA CCCCCCCCCCCCCCC	8.09	25884760
121	O-linked_Glycosylation	TATDYGYTQRQQEAP CCCCCCCCCCCCCCC	16.95	32574038
121	Phosphorylation	TATDYGYTQRQQEAP CCCCCCCCCCCCCCC	16.95	29978859
135	O-linked_Glycosylation	PPPPPPATTQNYQDS CCCCCCCCCCCCHHC	34.39	32574038
136	O-linked_Glycosylation	PPPPPATTQNYQDSY CCCCCCCCCCCHHCC	19.54	32574038
142	O-linked_Glycosylation	TTQNYQDSYSYVRST CCCCCHHCCCCHHHC	10.64	32574038
143	Phosphorylation	TQNYQDSYSYVRSTA CCCCHHCCCCHHHCC	16.59	-
144	O-linked_Glycosylation	QNYQDSYSYVRSTAP CCCHHCCCCHHHCCC	22.54	32574038
147	Methylation	QDSYSYVRSTAPAVA HHCCCCHHHCCCEEE	21.76	115388129
148	O-linked_Glycosylation	DSYSYVRSTAPAVAY HCCCCHHHCCCEEEC	20.91	32574038
148	Phosphorylation	DSYSYVRSTAPAVAY HCCCCHHHCCCEEEC	20.91	23403867
149	O-linked_Glycosylation	SYSYVRSTAPAVAYD CCCCHHHCCCEEECC	26.54	32574038
149	Phosphorylation	SYSYVRSTAPAVAYD CCCCHHHCCCEEECC	26.54	23403867
155	Phosphorylation	STAPAVAYDSKQYYQ HCCCEEECCCCCHHC	17.72	23403867
157	Phosphorylation	APAVAYDSKQYYQQP CCEEECCCCCHHCCC	14.69	23403867
158	Sumoylation	PAVAYDSKQYYQQPT CEEECCCCCHHCCCH	39.15	-
158	Ubiquitination	PAVAYDSKQYYQQPT CEEECCCCCHHCCCH	39.15	-
165	O-linked_Glycosylation	KQYYQQPTATAAAVA CCHHCCCHHHHHHHH	32.10	32574038
167	O-linked_Glycosylation	YYQQPTATAAAVAAA HHCCCHHHHHHHHHH	21.21	32574038
180	O-linked_Glycosylation	AAAQPQPSVAETYYQ HHHCCCCCHHHHHCC	28.81	32574038
186	Phosphorylation	PSVAETYYQTAPKAG CCHHHHHCCCCCCCC	13.55	17360941
194	Phosphorylation	QTAPKAGYSQGATQY CCCCCCCCCCCCCCC	11.59	21945579
195	O-linked_Glycosylation	TAPKAGYSQGATQYT CCCCCCCCCCCCCCC	22.63	46150317
195	Phosphorylation	TAPKAGYSQGATQYT CCCCCCCCCCCCCCC	22.63	21945579
195	O-linked_Glycosylation	TAPKAGYSQGATQYT CCCCCCCCCCCCCCC	22.63	20068230
199	O-linked_Glycosylation	AGYSQGATQYTQAQQ CCCCCCCCCCCCCCH	29.00	32574038
199	Phosphorylation	AGYSQGATQYTQAQQ CCCCCCCCCCCCCCH	29.00	21945579
201	Phosphorylation	YSQGATQYTQAQQTR CCCCCCCCCCCCHHC	9.10	21945579
202	O-linked_Glycosylation	SQGATQYTQAQQTRQ CCCCCCCCCCCHHCE	13.96	32574038
202	Phosphorylation	SQGATQYTQAQQTRQ CCCCCCCCCCCHHCE	13.96	21945579
202	O-linked_Glycosylation	SQGATQYTQAQQTRQ CCCCCCCCCCCHHCE	13.96	20068230
207	O-linked_Glycosylation	QYTQAQQTRQVTAIK CCCCCCHHCEEEEEC	15.81	32574038
211	O-linked_Glycosylation	AQQTRQVTAIKPATP CCHHCEEEEECCCCC	17.83	32574038
214	Ubiquitination	TRQVTAIKPATPSPA HCEEEEECCCCCCCC	26.57	-
217	O-linked_Glycosylation	VTAIKPATPSPATTT EEEECCCCCCCCCCE	32.59	32574038
219	O-linked_Glycosylation	AIKPATPSPATTTFS EECCCCCCCCCCEEE	23.86	32574038
223	O-linked_Glycosylation	ATPSPATTTFSIYPV CCCCCCCCEEEEEEC	28.13	32574038
226	O-linked_Glycosylation	SPATTTFSIYPVSST CCCCCEEEEEECCCC	21.08	32574038
231	O-linked_Glycosylation	TFSIYPVSSTVQPVA EEEEEECCCCCCCCE	18.78	32574038
233	O-linked_Glycosylation	SIYPVSSTVQPVAAA EEEECCCCCCCCEEE	18.69	32574038
242	O-linked_Glycosylation	QPVAAAATVVPSYTQ CCCEEEEEECCCCCC	19.81	32574038
246	O-linked_Glycosylation	AAATVVPSYTQSATY EEEEECCCCCCCEEE	29.24	32574038
248	O-linked_Glycosylation	ATVVPSYTQSATYST EEECCCCCCCEEEEE	22.01	32574038
250	O-linked_Glycosylation	VVPSYTQSATYSTTA ECCCCCCCEEEEEEE	18.12	32574038
256	O-linked_Glycosylation	QSATYSTTAVTYSGT CCEEEEEEEEEEECC	17.12	32574038
259	O-linked_Glycosylation	TYSTTAVTYSGTSYS EEEEEEEEEECCCCC	14.98	32574038
300	O-linked_Glycosylation	AAAAAAATAAWTGTT HHHHHHHHHHHHCCC	16.51	32574038
304	O-linked_Glycosylation	AAATAAWTGTTFTKK HHHHHHHHCCCCCCC	21.66	32574038
306	O-linked_Glycosylation	ATAAWTGTTFTKKAP HHHHHHCCCCCCCCC	16.03	32574038
307	O-linked_Glycosylation	TAAWTGTTFTKKAPF HHHHHCCCCCCCCCC	30.56	32574038
309	O-linked_Glycosylation	AWTGTTFTKKAPFQN HHHCCCCCCCCCCCC	29.55	32574038
310	Acetylation	WTGTTFTKKAPFQNK HHCCCCCCCCCCCCC	42.62	30585557
311	Ubiquitination	TGTTFTKKAPFQNKQ HCCCCCCCCCCCCCC	59.23	-
317	Acetylation	KKAPFQNKQLKPKQP CCCCCCCCCCCCCCC	46.34	19608861
317	Ubiquitination	KKAPFQNKQLKPKQP CCCCCCCCCCCCCCC	46.34	19608861
347	Ubiquitination	CAGPQTYKEHLEGQK ECCCHHHHHHHCCCC	41.88	-
363	Ubiquitination	KKKEAALKASQNTSS HHHHHHHHHHHCCCC	41.06	-
365	Phosphorylation	KEAALKASQNTSSSN HHHHHHHHHCCCCCC	23.52	21406692
368	Phosphorylation	ALKASQNTSSSNSST HHHHHHCCCCCCCCC	23.50	21406692
369	Phosphorylation	LKASQNTSSSNSSTR HHHHHCCCCCCCCCC	39.04	21406692
370	Phosphorylation	KASQNTSSSNSSTRG HHHHCCCCCCCCCCC	31.34	21406692
371	Phosphorylation	ASQNTSSSNSSTRGT HHHCCCCCCCCCCCC	40.26	21406692
373	Phosphorylation	QNTSSSNSSTRGTQN HCCCCCCCCCCCCCC	34.73	27251275
374	Phosphorylation	NTSSSNSSTRGTQNQ CCCCCCCCCCCCCCC	26.78	21406692
375	Phosphorylation	TSSSNSSTRGTQNQL CCCCCCCCCCCCCCC	32.70	21406692
390	Phosphorylation	RCELCDVSCTGADAY EEEEECCCCCCHHHH	7.84	28555341
422	O-linked_Glycosylation	KLGKPIPSTEPNVVS CCCCCCCCCCCCHHC	46.23	32574038
423	O-linked_Glycosylation	LGKPIPSTEPNVVSQ CCCCCCCCCCCHHCE	50.54	32574038
429	O-linked_Glycosylation	STEPNVVSQATSSTA CCCCCHHCEECCCCC	15.15	32574038
434	O-linked_Glycosylation	VVSQATSSTAVSASK HHCEECCCCCCCCCC	18.94	32574038
470	Phosphorylation	TSSMKGLTTTGNSSL CCCCCCCCCCCCCCC	30.86	20068231
471	O-linked_Glycosylation	SSMKGLTTTGNSSLN CCCCCCCCCCCCCCC	37.44	32574038
471	Phosphorylation	SSMKGLTTTGNSSLN CCCCCCCCCCCCCCC	37.44	20068231
472	Phosphorylation	SMKGLTTTGNSSLNS CCCCCCCCCCCCCCC	29.18	20068231
475	Phosphorylation	GLTTTGNSSLNSTSN CCCCCCCCCCCCCCC	37.23	20068231
476	Phosphorylation	LTTTGNSSLNSTSNT CCCCCCCCCCCCCCC	35.25	25159151
479	Phosphorylation	TGNSSLNSTSNTKVS CCCCCCCCCCCCEEC	38.21	20068231
480	Phosphorylation	GNSSLNSTSNTKVSA CCCCCCCCCCCEECC	25.56	20068231
481	Phosphorylation	NSSLNSTSNTKVSAV CCCCCCCCCCEECCC	42.18	25627689
486	Phosphorylation	STSNTKVSAVPTNMA CCCCCEECCCCCCCC	25.71	21406692
490	O-linked_Glycosylation	TKVSAVPTNMAAKKT CEECCCCCCCCCCCC	30.90	32574038
490	Phosphorylation	TKVSAVPTNMAAKKT CEECCCCCCCCCCCC	30.90	21406692
492	Sulfoxidation	VSAVPTNMAAKKTST ECCCCCCCCCCCCCC	4.17	21406390
495	Acetylation	VPTNMAAKKTSTPKI CCCCCCCCCCCCCCE	47.23	25953088
495	2-Hydroxyisobutyrylation	VPTNMAAKKTSTPKI CCCCCCCCCCCCCCE	47.23	-
496	Acetylation	PTNMAAKKTSTPKIN CCCCCCCCCCCCCEE	42.87	26051181
498	Phosphorylation	NMAAKKTSTPKINFV CCCCCCCCCCCEEEE	52.14	24719451
499	Phosphorylation	MAAKKTSTPKINFVG CCCCCCCCCCEEEEC	33.56	29214152
509	Acetylation	INFVGGNKLQSTGNK EEEECCCCCCCCCCC	51.70	19608861
509	Sumoylation	INFVGGNKLQSTGNK EEEECCCCCCCCCCC	51.70	28112733
516	Acetylation	KLQSTGNKAEDIKGT CCCCCCCCCHHHCCC	55.27	-
521	2-Hydroxyisobutyrylation	GNKAEDIKGTECVKS CCCCHHHCCCCCCCC	72.59	-
525	S-nitrosylation	EDIKGTECVKSTPVT HHHCCCCCCCCCCCC	4.73	22178444
527	Acetylation	IKGTECVKSTPVTSA HCCCCCCCCCCCCEE	61.34	26051181
528	Phosphorylation	KGTECVKSTPVTSAV CCCCCCCCCCCCEEE	19.97	22199227
528	O-linked_Glycosylation	KGTECVKSTPVTSAV CCCCCCCCCCCCEEE	19.97	32574038
529	Phosphorylation	GTECVKSTPVTSAVQ CCCCCCCCCCCEEEE	18.96	21815630
529	O-linked_Glycosylation	GTECVKSTPVTSAVQ CCCCCCCCCCCEEEE	18.96	32574038
532	O-linked_Glycosylation	CVKSTPVTSAVQIPE CCCCCCCCEEEECCC	16.51	32574038
532	Phosphorylation	CVKSTPVTSAVQIPE CCCCCCCCEEEECCC	16.51	27251275
533	Phosphorylation	VKSTPVTSAVQIPEV CCCCCCCEEEECCCC	27.03	29396449
541	Sumoylation	AVQIPEVKQDTVSEP EEECCCCCCCCCCCC	40.57	28112733
544	Phosphorylation	IPEVKQDTVSEPVTP CCCCCCCCCCCCCCH	24.36	30266825
546	Phosphorylation	EVKQDTVSEPVTPAS CCCCCCCCCCCCHHH	37.97	30266825
550	Phosphorylation	DTVSEPVTPASLAAL CCCCCCCCHHHHHHH	24.69	30266825
553	Phosphorylation	SEPVTPASLAALQSD CCCCCHHHHHHHHCC	21.53	30266825
559	Phosphorylation	ASLAALQSDVQPVGH HHHHHHHCCCCCCCC	40.37	30266825
568	Phosphorylation	VQPVGHDYVEEVRND CCCCCCCHHHHHHCC	12.23	29978859
585	Ubiquitination	KVIRFHCKLCECSFN CEEEEEEEECCCCCC	47.83	-
585	Acetylation	KVIRFHCKLCECSFN CEEEEEEEECCCCCC	47.83	26051181
590	Phosphorylation	HCKLCECSFNDPNAK EEEECCCCCCCCCHH	12.56	25159151
597	Acetylation	SFNDPNAKEMHLKGR CCCCCCHHHHHHCCH	63.31	26051181
610	Phosphorylation	GRRHRLQYKKKVNPD CHHHHHHHHCCCCCC	29.39	19658100
623	Acetylation	PDLQVEVKPSIRARK CCCCEEECHHHHHHH	21.38	26051181
623	Sumoylation	PDLQVEVKPSIRARK CCCCEEECHHHHHHH	21.38	28112733
625	Phosphorylation	LQVEVKPSIRARKIQ CCEEECHHHHHHHHH	20.99	28555341
645	Phosphorylation	KQMQKEEYWRRREEE HHHHHHHHHHHHHHH	12.81	28258704
662	Phosphorylation	WRMEMRRYEEDMYWR HHHHHHHHHHHHHHH	17.19	29759185
667	Phosphorylation	RRYEEDMYWRRMEEE HHHHHHHHHHHHHHH	14.21	17360941
703	Methylation	PLGLLGVRPGMPPQP CCCCCCCCCCCCCCC	21.91	115920369
721	Phosphorylation	APLRRPDSSDDRYVM CCCCCCCCCCCCEEE	38.05	28348404
722	Phosphorylation	PLRRPDSSDDRYVMT CCCCCCCCCCCEEEC	51.41	28348404
725	Methylation	RPDSSDDRYVMTKHA CCCCCCCCEEECCEE	30.82	115920373
729	Phosphorylation	SDDRYVMTKHATIYP CCCCEEECCEEEEEC	15.05	28985074
730	Ubiquitination	DDRYVMTKHATIYPT CCCEEECCEEEEECC	17.10	21890473
730	Acetylation	DDRYVMTKHATIYPT CCCEEECCEEEEECC	17.10	26051181
735	Phosphorylation	MTKHATIYPTEEELQ ECCEEEEECCHHHHH	10.35	28152594
737	Phosphorylation	KHATIYPTEEELQAV CEEEEECCHHHHHHH	38.77	28152594
756	Ubiquitination	SITERALKLVSDSLS HHHHHHHHHHHHHCH	45.95	-
756	2-Hydroxyisobutyrylation	SITERALKLVSDSLS HHHHHHHHHHHHHCH	45.95	-
756	Malonylation	SITERALKLVSDSLS HHHHHHHHHHHHHCH	45.95	26320211
756	Acetylation	SITERALKLVSDSLS HHHHHHHHHHHHHCH	45.95	25953088
759	Phosphorylation	ERALKLVSDSLSEHE HHHHHHHHHHCHHHH	31.73	-
761	Phosphorylation	ALKLVSDSLSEHEKN HHHHHHHHCHHHHHH	26.70	-
763	Phosphorylation	KLVSDSLSEHEKNKN HHHHHHCHHHHHHCC	40.64	-
767	Acetylation	DSLSEHEKNKNKEGD HHCHHHHHHCCCCCC	75.12	25953088
786	Malonylation	GGKDRALKGVLRVGV CCHHHHHHHHHHHHH	46.09	26320211
796	Ubiquitination	LRVGVLAKGLLLRGD HHHHHHHHCEECCCC	46.03	21890473
815	2-Hydroxyisobutyrylation	LVLLCSEKPSKTLLS EEEEECCCCCHHHHH	37.99	-
815	Acetylation	LVLLCSEKPSKTLLS EEEEECCCCCHHHHH	37.99	26051181
839	Acetylation	LAVISPEKYDIKCAV EEECCHHHCCCHHHH	52.16	25953088
847	Phosphorylation	YDIKCAVSEAAIILN CCCHHHHCHHHHHHH	11.73	29978859
855	Phosphorylation	EAAIILNSCVEPKMQ HHHHHHHHCCCCCCE	18.98	29978859
864	Phosphorylation	VEPKMQVTITLTSPI CCCCCEEEEEEECHH	7.43	26552605
866	Phosphorylation	PKMQVTITLTSPIIR CCCEEEEEEECHHHC	18.02	26552605
868	Phosphorylation	MQVTITLTSPIIREE CEEEEEEECHHHCHH	24.65	26552605
869	Phosphorylation	QVTITLTSPIIREEN EEEEEEECHHHCHHH	19.74	26552605
883	Phosphorylation	NMREGDVTSGMVKDP HCCCCCCCCCCCCCC	25.05	20860994
884	Phosphorylation	MREGDVTSGMVKDPP CCCCCCCCCCCCCCC	25.41	20860994
888	Acetylation	DVTSGMVKDPPDVLD CCCCCCCCCCCCCCC	56.47	26051181
898	2-Hydroxyisobutyrylation	PDVLDRQKCLDALAA CCCCCHHHHHHHHHH	37.34	-
910	Acetylation	LAALRHAKWFQARAN HHHHHHHHHHHHHHC	42.27	22631573
910	Ubiquitination	LAALRHAKWFQARAN HHHHHHHHHHHHHHC	42.27	-
956	Phosphorylation	LLVEKAISSASSPQS HHHHHHHHCCCCCCC	25.39	21406692
957	Phosphorylation	LVEKAISSASSPQSP HHHHHHHCCCCCCCH	26.51	21406692
959	Phosphorylation	EKAISSASSPQSPGD HHHHHCCCCCCCHHH	44.49	21406692
960	Phosphorylation	KAISSASSPQSPGDA HHHHCCCCCCCHHHH	27.03	21406692
960	O-linked_Glycosylation	KAISSASSPQSPGDA HHHHCCCCCCCHHHH	27.03	32574038
963	Phosphorylation	SSASSPQSPGDALRR HCCCCCCCHHHHHHH	33.95	21406692
963	O-linked_Glycosylation	SSASSPQSPGDALRR HCCCCCCCHHHHHHH	33.95	32574038
993	Acetylation	GLLDPCEKDPFDTLA CCCCCCCCCCCCCHH	76.92	26051181
1039	Phosphorylation	MDPLPQMSQRFNIHN CCCCCHHHHHCCCCC	16.98	23917254
1054	Phosphorylation	NRKRRRDSDGVDGFE CCCCCCCCCCCCCCH	34.16	29255136
1065	Acetylation	DGFEAEGKKDKKDYD CCCHHCCCCCCCCCC	49.67	7373333
1066	Acetylation	GFEAEGKKDKKDYDN CCHHCCCCCCCCCCC	82.63	7824229
1068	Acetylation	EAEGKKDKKDYDNF- HHCCCCCCCCCCCC-	57.32	7373345

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZFR_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZFR_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZFR_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
DNMT1_HUMAN	DNMT1	physical	26344197
ILF2_HUMAN	ILF2	physical	26344197

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZFR_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-317; LYS-509 AND LYS-910,AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1054, AND MASSSPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1054, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry."; Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.; Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1054, AND MASSSPECTROMETRY.	17287340 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-476 AND SER-1054, ANDMASS SPECTROMETRY.	17081983 [Abstract]