RM43_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM43_HUMAN
• UniProt AC: Q8N983
• Protein Name: 39S ribosomal protein L43, mitochondrial
• Gene Name: MRPL43
• Organism: Homo sapiens (Human).
• Sequence Length: 215
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MTARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSGLDVIRIRKPFHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDPAPAQDTGLRLSAVAPQILLPGWPDPPDLPTVDPISSSLTSAPAPMLSAVSCLPIVPALTTVCSA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Methylation	----MTARGTPSRFL ----CCCCCCHHHHH	40.11	115483789
22	Phosphorylation	LHNGLGRYVQQLQRL HHCCHHHHHHHHHHH	10.79	28152594
30	Phosphorylation	VQQLQRLSFSVSRDG HHHHHHHCCEECCCC	20.05	27251275
32	Phosphorylation	QLQRLSFSVSRDGAS HHHHHCCEECCCCCC	18.79	27251275
93	Phosphorylation	EESIHCKSVEEISTL CCCCCCCCHHHHHHH	39.91	27251275
103	Ubiquitination	EISTLVQKLADQSGL HHHHHHHHHHHHCCC	37.86	-
117	Ubiquitination	LDVIRIRKPFHTDNP CCEEEECCCCCCCCC	50.06	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM43_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM43_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM43_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RM47_HUMAN	MRPL47	physical	22939629
RS18_HUMAN	RPS18	physical	22939629
NACC1_HUMAN	NACC1	physical	26186194
SLK_HUMAN	SLK	physical	26186194
RM39_HUMAN	MRPL39	physical	26186194
GLSK_HUMAN	GLS	physical	26186194
RM44_HUMAN	MRPL44	physical	26186194
RM20_HUMAN	MRPL20	physical	26186194
NDUF5_HUMAN	NDUFAF5	physical	26186194
RM04_HUMAN	MRPL4	physical	26186194
RM42_HUMAN	MRPL42	physical	26186194
MASU1_HUMAN	MALSU1	physical	26186194
RT30_HUMAN	MRPS30	physical	26186194
NACC1_HUMAN	NACC1	physical	28514442
SLK_HUMAN	SLK	physical	28514442
NDUF5_HUMAN	NDUFAF5	physical	28514442
RT30_HUMAN	MRPS30	physical	28514442
RM44_HUMAN	MRPL44	physical	28514442
GLSK_HUMAN	GLS	physical	28514442
RM04_HUMAN	MRPL4	physical	28514442
RM20_HUMAN	MRPL20	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.