ZN554_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN554_HUMAN
• UniProt AC: Q86TJ5
• Protein Name: Zinc finger protein 554
• Gene Name: ZNF554
• Organism: Homo sapiens (Human).
• Sequence Length: 538
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MVTCAHLGRRARLPAAQPSACPGTCFSQEERMAAGYLPRWSQELVTFEDVSMDFSQEEWELLEPAQKNLYREVMLENYRNVVSLEALKNQCTDVGIKEGPLSPAQTSQVTSLSSWTGYLLFQPVASSHLEQREALWIEEKGTPQASCSDWMTVLRNQDSTYKKVALQEEPASGINMIKLIREDGGWKQLEDSHEDPQGLLSQKASLHVVAVPQEKATAWHGFGENGNLSPALVLSQGSSKGNHLCGSELDITSLASDSVLNHHQLGYADRRPCESNECGNAIRQNSHFIQHGGKMFVYLENGQSLNHGMALTIHNKINTAEKPFECHQCGKVFNRRHSLSEHQRIHTGEKPYECQECGRAFTHSSTLTRHLRTHTGEKPYGCGECGKAFNRISSLTQHQRIHTGEKPYKCEDCGKSFCQSSYLILHKRTHTGEKPYECSECGKAFSDRSSLNQHERTHTGENPYECKQCGRAFSQRSSLVRHERTHTGEKPYRCQECGKAFSQSSSLVTHQKTHSSQKTYKIIDCGKAFYQNRHLIGY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
178	Sumoylation	ASGINMIKLIREDGG CCCCCCEEEEEECCC	27.39	28112733
229	Phosphorylation	FGENGNLSPALVLSQ CCCCCCCCCEEEECC	16.48	25159151
338	O-linked_Glycosylation	KVFNRRHSLSEHQRI CCCCCCCCCCCCCCC	31.60	OGP
338	Phosphorylation	KVFNRRHSLSEHQRI CCCCCCCCCCCCCCC	31.60	29449344
340	Phosphorylation	FNRRHSLSEHQRIHT CCCCCCCCCCCCCCC	35.73	29449344
340	O-linked_Glycosylation	FNRRHSLSEHQRIHT CCCCCCCCCCCCCCC	35.73	OGP
347	Phosphorylation	SEHQRIHTGEKPYEC CCCCCCCCCCCCCCC	44.67	28111955
373	Phosphorylation	TLTRHLRTHTGEKPY HHHHHHHHCCCCCCC	30.10	-
375	Phosphorylation	TRHLRTHTGEKPYGC HHHHHHCCCCCCCCC	46.56	-
403	Phosphorylation	TQHQRIHTGEKPYKC CCCCCCCCCCCCCCC	44.67	29496963
406	Ubiquitination	QRIHTGEKPYKCEDC CCCCCCCCCCCCCCC	55.80	-
409	Sumoylation	HTGEKPYKCEDCGKS CCCCCCCCCCCCCCC	39.41	-
409	Sumoylation	HTGEKPYKCEDCGKS CCCCCCCCCCCCCCC	39.41	-
409	Ubiquitination	HTGEKPYKCEDCGKS CCCCCCCCCCCCCCC	39.41	-
429	Phosphorylation	YLILHKRTHTGEKPY EEEEECCCCCCCCCE	28.70	-
431	Phosphorylation	ILHKRTHTGEKPYEC EEECCCCCCCCCEEC	46.56	-
434	Ubiquitination	KRTHTGEKPYECSEC CCCCCCCCCEECCCC	55.00	-
439	Phosphorylation	GEKPYECSECGKAFS CCCCEECCCCCCCCC	24.79	-
477	Phosphorylation	GRAFSQRSSLVRHER CCHHHHHHHHHHCCC	22.01	25137130
478	Phosphorylation	RAFSQRSSLVRHERT CHHHHHHHHHHCCCC	32.83	24719451
485	Phosphorylation	SLVRHERTHTGEKPY HHHHCCCCCCCCCCE	22.32	-
487	Phosphorylation	VRHERTHTGEKPYRC HHCCCCCCCCCCEEH	46.56	24719451
490	Acetylation	ERTHTGEKPYRCQEC CCCCCCCCCEEHHHH	49.01	30593783
519	Phosphorylation	KTHSSQKTYKIIDCG CCCCCCCEEEEEECC	23.55	-
520	Phosphorylation	THSSQKTYKIIDCGK CCCCCCEEEEEECCH	13.76	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN554_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN554_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN554_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN554_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.