DHI1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DHI1L_HUMAN
• UniProt AC: Q7Z5J1
• Protein Name: Hydroxysteroid 11-beta-dehydrogenase 1-like protein
• Gene Name: HSD11B1L
• Organism: Homo sapiens (Human).
• Sequence Length: 315
• Subcellular Localization: Secreted .
• Protein Sequence: MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
123	Phosphorylation	IGGAPAGTRARSPQA CCCCCCCCCCCCHHH	24.22	-
141	Phosphorylation	LMQVNFVSYVQLTSR HHHCCCCCHHHHHHC	18.56	23663014
142	Phosphorylation	MQVNFVSYVQLTSRA HHCCCCCHHHHHHCC	6.21	23663014
146	Phosphorylation	FVSYVQLTSRALPSL CCCHHHHHHCCCCCC	10.08	23663014
147	Phosphorylation	VSYVQLTSRALPSLT CCHHHHHHCCCCCCC	24.93	23663014
152	Phosphorylation	LTSRALPSLTDSKGS HHHCCCCCCCCCCCC	44.76	18491316
154	Phosphorylation	SRALPSLTDSKGSLV HCCCCCCCCCCCCEE	42.43	21406692
156	Phosphorylation	ALPSLTDSKGSLVVV CCCCCCCCCCCEEEE	33.41	21406692
159	Phosphorylation	SLTDSKGSLVVVSSL CCCCCCCCEEEEECC	23.02	21406692
164	Phosphorylation	KGSLVVVSSLLGRVP CCCEEEEECCCCCCC	12.03	18491316
165	Phosphorylation	GSLVVVSSLLGRVPT CCEEEEECCCCCCCC	18.92	21406692
172	Phosphorylation	SLLGRVPTSFSTPYS CCCCCCCCCCCCHHH	39.28	24043423
173	Phosphorylation	LLGRVPTSFSTPYSA CCCCCCCCCCCHHHH	15.89	24043423
175	Phosphorylation	GRVPTSFSTPYSAAK CCCCCCCCCHHHHHH	28.39	24043423
176	Phosphorylation	RVPTSFSTPYSAAKF CCCCCCCCHHHHHHH	25.00	24043423
178	Phosphorylation	PTSFSTPYSAAKFAL CCCCCCHHHHHHHHH	15.84	19413330
179	Phosphorylation	TSFSTPYSAAKFALD CCCCCHHHHHHHHHH	23.97	24043423
217	Phosphorylation	LGLRDRASAAEAVRS HHCCCHHHHHHHHHH	28.98	26471730
243	Phosphorylation	GVPLQSQTAMFLPPT CCCCCCCCEEECCCC	25.90	-
260	Phosphorylation	GARTLTETPLRGWPQ CCCCCCCCCCCCCCC	23.53	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DHI1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DHI1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DHI1L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of DHI1L_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.