APC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: APC_HUMAN
• UniProt AC: P25054
• Protein Name: Adenomatous polyposis coli protein
• Gene Name: APC {ECO:0000312|HGNC:HGNC:583}
• Organism: Homo sapiens (Human).
• Sequence Length: 2843
• Subcellular Localization: Cell junction, adherens junction . Cytoplasm, cytoskeleton . Cell projection, lamellipodium . Cell projection, ruffle membrane . Cytoplasm . Cell membrane . Associated with the microtubule network at the growing distal tip of microtubules (PubMed:196
• Protein Description: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization..
• Protein Sequence: MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAASYDQL ------CCCCHHHHH	24.04	22814378
5	Phosphorylation	---MAAASYDQLLKQ ---CCCCHHHHHHHH	25.23	24719451
21	Phosphorylation	EALKMENSNLRQELE HHHHCCCCCHHHHHH	24.76	28555341
31	Phosphorylation	RQELEDNSNHLTKLE HHHHHHCCHHHHHHH	37.64	23401153
35	Phosphorylation	EDNSNHLTKLETEAS HHCCHHHHHHHHHHH	26.49	23401153
39	Phosphorylation	NHLTKLETEASNMKE HHHHHHHHHHHHHHH	47.49	23401153
42	Phosphorylation	TKLETEASNMKEVLK HHHHHHHHHHHHHHH	31.09	23401153
62	Phosphorylation	IEDEAMASSGQIDLL HHHHHHHCCCCHHHH	23.16	24275569
73	Ubiquitination	IDLLERLKELNLDSS HHHHHHHHHCCCCCC	67.39	-
79	Phosphorylation	LKELNLDSSNFPGVK HHHCCCCCCCCCCCC	30.28	28509920
80	Phosphorylation	KELNLDSSNFPGVKL HHCCCCCCCCCCCCC	42.00	25159151
89	Phosphorylation	FPGVKLRSKMSLRSY CCCCCCCCCEECHHC	43.05	23403867
92	Phosphorylation	VKLRSKMSLRSYGSR CCCCCCEECHHCCCC	25.11	24719451
95	Phosphorylation	RSKMSLRSYGSREGS CCCEECHHCCCCCCC	38.86	29449344
96	Phosphorylation	SKMSLRSYGSREGSV CCEECHHCCCCCCCC	16.82	22461510
98	Phosphorylation	MSLRSYGSREGSVSS EECHHCCCCCCCCCC	20.94	29449344
102	Phosphorylation	SYGSREGSVSSRSGE HCCCCCCCCCCCCCC	17.67	29449344
107	Phosphorylation	EGSVSSRSGECSPVP CCCCCCCCCCCCCCC	40.67	25159151
111	Phosphorylation	SSRSGECSPVPMGSF CCCCCCCCCCCCCCC	25.32	25159151
117	Phosphorylation	CSPVPMGSFPRRGFV CCCCCCCCCCCCCCC	26.31	27732954
127	Phosphorylation	RRGFVNGSRESTGYL CCCCCCCCCCCCCHH	27.89	30266825
130	Phosphorylation	FVNGSRESTGYLEEL CCCCCCCCCCHHHHH	26.48	30266825
131	Phosphorylation	VNGSRESTGYLEELE CCCCCCCCCHHHHHH	25.70	30266825
133	Phosphorylation	GSRESTGYLEELEKE CCCCCCCHHHHHHHH	15.84	28102081
142	Phosphorylation	EELEKERSLLLADLD HHHHHHHCHHHHCCC	25.18	28555341
150	Ubiquitination	LLLADLDKEEKEKDW HHHHCCCHHHHHHHH	75.07	-
158	Phosphorylation	EEKEKDWYYAQLQNL HHHHHHHHHHHHHHH	10.08	28270605
159	Phosphorylation	EKEKDWYYAQLQNLT HHHHHHHHHHHHHHH	5.43	28270605
288	Phosphorylation	TTRMDHETASVLSSS CCCCCHHHHHHHCCC	22.32	20873877
290	Phosphorylation	RMDHETASVLSSSST CCCHHHHHHHCCCCC	30.89	20873877
293	Phosphorylation	HETASVLSSSSTHSA HHHHHHHCCCCCCCC	26.47	23663014
294	Phosphorylation	ETASVLSSSSTHSAP HHHHHHCCCCCCCCC	24.93	23663014
295	Phosphorylation	TASVLSSSSTHSAPR HHHHHCCCCCCCCCH	35.56	23663014
296	Phosphorylation	ASVLSSSSTHSAPRR HHHHCCCCCCCCCHH	31.89	23663014
297	Phosphorylation	SVLSSSSTHSAPRRL HHHCCCCCCCCCHHH	23.07	23663014
299	Phosphorylation	LSSSSTHSAPRRLTS HCCCCCCCCCHHHHH	39.80	23663014
305	Phosphorylation	HSAPRRLTSHLGTKV CCCCHHHHHHHHHHH	16.58	20068231
306	Phosphorylation	SAPRRLTSHLGTKVE CCCHHHHHHHHHHHH	22.70	22210691
310	Phosphorylation	RLTSHLGTKVEMVYS HHHHHHHHHHHHHHH	37.97	20068231
316	Phosphorylation	GTKVEMVYSLLSMLG HHHHHHHHHHHHHHC	7.71	20068231
317	Phosphorylation	TKVEMVYSLLSMLGT HHHHHHHHHHHHHCC	16.07	20068231
320	Phosphorylation	EMVYSLLSMLGTHDK HHHHHHHHHHCCCCC	19.77	20068231
324	Phosphorylation	SLLSMLGTHDKDDMS HHHHHHCCCCCCHHH	23.96	20068231
331	Phosphorylation	THDKDDMSRTLLAMS CCCCCHHHHHHHHHC	29.16	-
333	Phosphorylation	DKDDMSRTLLAMSSS CCCHHHHHHHHHCCC	20.86	-
552	Phosphorylation	ASVLRNLSWRADVNS HHHHHHCCHHCCCCC	20.33	24719451
559	Phosphorylation	SWRADVNSKKTLREV CHHCCCCCHHHHHHH	35.06	29083192
561	"N6,N6-dimethyllysine"	RADVNSKKTLREVGS HCCCCCHHHHHHHHH	53.24	-
561	Methylation	RADVNSKKTLREVGS HCCCCCHHHHHHHHH	53.24	-
580	"N6,N6-dimethyllysine"	MECALEVKKESTLKS HHHHHHHCCHHHHHH	41.26	-
580	Methylation	MECALEVKKESTLKS HHHHHHHCCHHHHHH	41.26	-
600	Phosphorylation	WNLSAHCTENKADIC HHHHHHHCCCHHHHH	32.50	-
705	Phosphorylation	LWDMGAVSMLKNLIH HHHHHHHHHHHHHHH	20.19	29116813
713	Phosphorylation	MLKNLIHSKHKMIAM HHHHHHHCHHHHHHH	29.48	29116813
722	Phosphorylation	HKMIAMGSAAALRNL HHHHHHHHHHHHHHH	11.14	17322306
737	Phosphorylation	MANRPAKYKDANIMS HHCCCCCCCCCCCCC	19.06	28464451
744	Phosphorylation	YKDANIMSPGSSLPS CCCCCCCCCCCCCCC	23.47	25159151
747	Phosphorylation	ANIMSPGSSLPSLHV CCCCCCCCCCCCHHH	31.89	22617229
748	Phosphorylation	NIMSPGSSLPSLHVR CCCCCCCCCCCHHHH	50.65	25159151
751	Phosphorylation	SPGSSLPSLHVRKQK CCCCCCCCHHHHHHH	36.08	23663014
770	Phosphorylation	ELDAQHLSETFDNID HHHHHHHHHHHCCHH	32.25	26657352
772	Phosphorylation	DAQHLSETFDNIDNL HHHHHHHHHCCHHHC	32.67	30266825
780	Phosphorylation	FDNIDNLSPKASHRS HCCHHHCCHHHHHHH	30.52	25159151
794	Phosphorylation	SKQRHKQSLYGDYVF HHHHHHHHHHCCEEE	28.50	23312004
796	Phosphorylation	QRHKQSLYGDYVFDT HHHHHHHHCCEEECC	17.13	29978859
799	Phosphorylation	KQSLYGDYVFDTNRH HHHHHCCEEECCCCC	9.92	29978859
803	Phosphorylation	YGDYVFDTNRHDDNR HCCEEECCCCCCCCC	23.76	29978859
843	Phosphorylation	SSRGSLDSSRSEKDR CCCCCCCCCCCHHHH	32.70	23312004
844	Phosphorylation	SRGSLDSSRSEKDRS CCCCCCCCCCHHHHH	39.22	23312004
846	Phosphorylation	GSLDSSRSEKDRSLE CCCCCCCCHHHHHHH	51.45	28102081
851	Phosphorylation	SRSEKDRSLERERGI CCCHHHHHHHHHCCC	44.72	30576142
863	Phosphorylation	RGIGLGNYHPATENP CCCCCCCCCCCCCCC	13.84	21945579
867	Phosphorylation	LGNYHPATENPGTSS CCCCCCCCCCCCCCC	40.52	20068231
872	Phosphorylation	PATENPGTSSKRGLQ CCCCCCCCCCCCCCC	30.96	25159151
873	Phosphorylation	ATENPGTSSKRGLQI CCCCCCCCCCCCCCC	39.51	23312004
874	Phosphorylation	TENPGTSSKRGLQIS CCCCCCCCCCCCCCH	26.64	21945579
881	Phosphorylation	SKRGLQISTTAAQIA CCCCCCCHHHHHHHH	13.52	20068231
882	Phosphorylation	KRGLQISTTAAQIAK CCCCCCHHHHHHHHH	23.29	20068231
883	O-linked_Glycosylation	RGLQISTTAAQIAKV CCCCCHHHHHHHHHH	17.13	30059200
883	Phosphorylation	RGLQISTTAAQIAKV CCCCCHHHHHHHHHH	17.13	20068231
895	Phosphorylation	AKVMEEVSAIHTSQE HHHHHHHHCCCCCHH	25.45	20166139
899	Phosphorylation	EEVSAIHTSQEDRSS HHHHCCCCCHHHHCC	26.45	20166139
905	Phosphorylation	HTSQEDRSSGSTTEL CCCHHHHCCCCCEEE	51.91	23663014
906	Phosphorylation	TSQEDRSSGSTTELH CCHHHHCCCCCEEEE	37.34	23663014
908	Phosphorylation	QEDRSSGSTTELHCV HHHHCCCCCEEEEEE	33.82	22617229
909	Phosphorylation	EDRSSGSTTELHCVT HHHCCCCCEEEEEEC	28.02	23663014
910	Phosphorylation	DRSSGSTTELHCVTD HHCCCCCEEEEEECC	37.94	23663014
925	Phosphorylation	ERNALRRSSAAHTHS CHHHHHHHHCCCCCC	20.21	21945579
926	Phosphorylation	RNALRRSSAAHTHSN HHHHHHHHCCCCCCC	27.88	21945579
930	Phosphorylation	RRSSAAHTHSNTYNF HHHHCCCCCCCCCCC	23.44	21945579
932	Phosphorylation	SSAAHTHSNTYNFTK HHCCCCCCCCCCCCC	31.83	21945579
934	Phosphorylation	AAHTHSNTYNFTKSE CCCCCCCCCCCCCCC	23.90	21945579
935	Phosphorylation	AHTHSNTYNFTKSEN CCCCCCCCCCCCCCC	16.72	21945579
938	Phosphorylation	HSNTYNFTKSENSNR CCCCCCCCCCCCCCC	29.98	21945579
939	Ubiquitination	SNTYNFTKSENSNRT CCCCCCCCCCCCCCE	52.19	-
951	Phosphorylation	NRTCSMPYAKLEYKR CCEECCCEEEEEECC	14.02	21945579
958	Methylation	YAKLEYKRSSNDSLN EEEEEECCCCCCCCC	44.40	-
959	Phosphorylation	AKLEYKRSSNDSLNS EEEEECCCCCCCCCC	29.37	23401153
960	Phosphorylation	KLEYKRSSNDSLNSV EEEECCCCCCCCCCC	49.00	23401153
963	Phosphorylation	YKRSSNDSLNSVSSS ECCCCCCCCCCCHHC	33.43	23663014
966	Phosphorylation	SSNDSLNSVSSSDGY CCCCCCCCCHHCCCC	28.77	23401153
968	Phosphorylation	NDSLNSVSSSDGYGK CCCCCCCHHCCCCCC	24.76	23401153
969	Phosphorylation	DSLNSVSSSDGYGKR CCCCCCHHCCCCCCC	30.23	23401153
970	Phosphorylation	SLNSVSSSDGYGKRG CCCCCHHCCCCCCCC	27.78	27732954
973	Phosphorylation	SVSSSDGYGKRGQMK CCHHCCCCCCCCCCC	25.19	23090842
976	Methylation	SSDGYGKRGQMKPSI HCCCCCCCCCCCCCC	35.89	-
982	Phosphorylation	KRGQMKPSIESYSED CCCCCCCCCCCCCCC	33.21	27732954
985	Phosphorylation	QMKPSIESYSEDDES CCCCCCCCCCCCCCC	32.08	22496350
986	Phosphorylation	MKPSIESYSEDDESK CCCCCCCCCCCCCCC	11.86	27732954
987	Phosphorylation	KPSIESYSEDDESKF CCCCCCCCCCCCCCC	43.77	28355574
992	Phosphorylation	SYSEDDESKFCSYGQ CCCCCCCCCCCCCCC	37.72	27732954
996	Phosphorylation	DDESKFCSYGQYPAD CCCCCCCCCCCCHHH	35.12	21945579
997	Phosphorylation	DESKFCSYGQYPADL CCCCCCCCCCCHHHH	14.94	21945579
1000	Phosphorylation	KFCSYGQYPADLAHK CCCCCCCCHHHHHHH	8.95	21945579
1023	Phosphorylation	DNDGELDTPINYSLK CCCCCCCCCCEEEEE	38.40	27422710
1027	Phosphorylation	ELDTPINYSLKYSDE CCCCCCEEEEECCHH	18.99	27642862
1028	Phosphorylation	LDTPINYSLKYSDEQ CCCCCEEEEECCHHH	17.56	29978859
1031	Phosphorylation	PINYSLKYSDEQLNS CCEEEEECCHHHHHC	27.01	23403867
1032	Phosphorylation	INYSLKYSDEQLNSG CEEEEECCHHHHHCC	32.84	23927012
1038	Phosphorylation	YSDEQLNSGRQSPSQ CCHHHHHCCCCCCCC	43.90	25159151
1042	Phosphorylation	QLNSGRQSPSQNERW HHHCCCCCCCCCCCC	25.76	23927012
1044	Phosphorylation	NSGRQSPSQNERWAR HCCCCCCCCCCCCCC	51.38	23927012
1063	Phosphorylation	IEDEIKQSEQRQSRN HHHHHHHHHHHHHCC	30.60	25159151
1072	Phosphorylation	QRQSRNQSTTYPVYT HHHHCCCCCCCCEEE	26.68	27642862
1073	Phosphorylation	RQSRNQSTTYPVYTE HHHCCCCCCCCEEEC	22.15	21945579
1074	Phosphorylation	QSRNQSTTYPVYTES HHCCCCCCCCEEECC	30.95	28555341
1075	Phosphorylation	SRNQSTTYPVYTEST HCCCCCCCCEEECCC	7.26	27642862
1078	Phosphorylation	QSTTYPVYTESTDDK CCCCCCEEECCCCCC	10.57	21945579
1079	Phosphorylation	STTYPVYTESTDDKH CCCCCEEECCCCCCC	24.56	21945579
1081	Phosphorylation	TYPVYTESTDDKHLK CCCEEECCCCCCCCC	29.36	21945579
1082	Phosphorylation	YPVYTESTDDKHLKF CCEEECCCCCCCCCC	41.82	21945579
1100	Phosphorylation	FGQQECVSPYRSRGA CCCCCCCCCCHHCCC	28.07	25159151
1102	Phosphorylation	QQECVSPYRSRGANG CCCCCCCCHHCCCCC	17.45	28450419
1104	Phosphorylation	ECVSPYRSRGANGSE CCCCCCHHCCCCCCC	29.26	27174698
1117	Phosphorylation	SETNRVGSNHGINQN CCCCCCCCCCCCCCC	23.85	28985074
1126	Phosphorylation	HGINQNVSQSLCQED CCCCCCCCHHHHCCC	22.92	29978859
1128	Phosphorylation	INQNVSQSLCQEDDY CCCCCCHHHHCCCCC	24.49	29978859
1135	Phosphorylation	SLCQEDDYEDDKPTN HHHCCCCCCCCCCCC	33.31	27642862
1143	Phosphorylation	EDDKPTNYSERYSEE CCCCCCCHHHCCCHH	17.87	29978859
1144	Phosphorylation	DDKPTNYSERYSEEE CCCCCCHHHCCCHHH	20.05	27642862
1147	Phosphorylation	PTNYSERYSEEEQHE CCCHHHCCCHHHHCC	19.18	29449344
1148	Phosphorylation	TNYSERYSEEEQHEE CCHHHCCCHHHHCCC	44.76	28985074
1163	Phosphorylation	EERPTNYSIKYNEEK CCCCCCCCCCCCCHH	18.05	24719451
1179	Phosphorylation	HVDQPIDYSLKYATD CCCCCCCHHEEECCC	19.34	27642862
1180	Phosphorylation	VDQPIDYSLKYATDI CCCCCCHHEEECCCC	18.03	19060867
1183	Phosphorylation	PIDYSLKYATDIPSS CCCHHEEECCCCCCC	21.74	22461510
1189	Phosphorylation	KYATDIPSSQKQSFS EECCCCCCCCCEEEE	45.82	21815630
1194	Phosphorylation	IPSSQKQSFSFSKSS CCCCCCEEEECCCCC	29.87	-
1196	Phosphorylation	SSQKQSFSFSKSSSG CCCCEEEECCCCCCC	33.58	24719451
1214	Phosphorylation	KTEHMSSSSENTSTP CCEECCCCCCCCCCC	34.07	-
1215	Phosphorylation	TEHMSSSSENTSTPS CEECCCCCCCCCCCC	36.49	-
1218	Phosphorylation	MSSSSENTSTPSSNA CCCCCCCCCCCCHHH	29.90	25159151
1219	Phosphorylation	SSSSENTSTPSSNAK CCCCCCCCCCCHHHH	50.32	25159151
1220	Phosphorylation	SSSENTSTPSSNAKR CCCCCCCCCCHHHHH	25.75	25159151
1222	Phosphorylation	SENTSTPSSNAKRQN CCCCCCCCHHHHHHH	35.99	-
1223	Phosphorylation	ENTSTPSSNAKRQNQ CCCCCCCHHHHHHHC	41.85	-
1234	Phosphorylation	RQNQLHPSSAQSRSG HHHCCCCCCCCCCCC	27.79	25159151
1235	Phosphorylation	QNQLHPSSAQSRSGQ HHCCCCCCCCCCCCC	34.48	25159151
1238	Phosphorylation	LHPSSAQSRSGQPQK CCCCCCCCCCCCCCC	28.29	25159151
1252	Phosphorylation	KAATCKVSSINQETI CCCEEEECCCCHHHH	15.82	28555341
1253	Phosphorylation	AATCKVSSINQETIQ CCEEEECCCCHHHHH	28.66	28555341
1267	Phosphorylation	QTYCVEDTPICFSRC HHEECCCCCCCEEEC	10.88	27251275
1272	Phosphorylation	EDTPICFSRCSSLSS CCCCCCEEECCCCHH	28.15	24719451
1278	Phosphorylation	FSRCSSLSSLSSAED EEECCCCHHCCCCCC	31.05	-
1279	Phosphorylation	SRCSSLSSLSSAEDE EECCCCHHCCCCCCC	37.25	22817900
1292	Phosphorylation	DEIGCNQTTQEADSA CCCCCCCCCCCCHHC	19.22	-
1301	Phosphorylation	QEADSANTLQIAEIK CCCHHCCCHHHHHHH	21.54	-
1313	Phosphorylation	EIKEKIGTRSAEDPV HHHHHHCCCCCCCCH	25.56	22210691
1315	Phosphorylation	KEKIGTRSAEDPVSE HHHHCCCCCCCCHHH	35.53	27050516
1321	Phosphorylation	RSAEDPVSEVPAVSQ CCCCCCHHHCCCCCC	37.96	22210691
1327	Phosphorylation	VSEVPAVSQHPRTKS HHHCCCCCCCCCCCC	25.52	23312004
1340	Phosphorylation	KSSRLQGSSLSSESA CCCCCCCCCCCCHHH	18.36	20873877
1341	Phosphorylation	SSRLQGSSLSSESAR CCCCCCCCCCCHHHH	38.81	25159151
1343	Phosphorylation	RLQGSSLSSESARHK CCCCCCCCCHHHHHH	33.73	25159151
1344	Phosphorylation	LQGSSLSSESARHKA CCCCCCCCHHHHHHH	40.64	20873877
1346	Phosphorylation	GSSLSSESARHKAVE CCCCCCHHHHHHHHC	32.33	25159151
1355	Phosphorylation	RHKAVEFSSGAKSPS HHHHHCCCCCCCCCC	17.85	23927012
1356	Phosphorylation	HKAVEFSSGAKSPSK HHHHCCCCCCCCCCC	48.36	30266825
1360	Phosphorylation	EFSSGAKSPSKSGAQ CCCCCCCCCCCCCCC	33.59	22167270
1362	Phosphorylation	SSGAKSPSKSGAQTP CCCCCCCCCCCCCCC	46.69	30266825
1364	Phosphorylation	GAKSPSKSGAQTPKS CCCCCCCCCCCCCCC	43.64	22199227
1368	Phosphorylation	PSKSGAQTPKSPPEH CCCCCCCCCCCCCHH	31.95	30576142
1371	Phosphorylation	SGAQTPKSPPEHYVQ CCCCCCCCCCHHHCC	47.06	30266825
1376	Phosphorylation	PKSPPEHYVQETPLM CCCCCHHHCCCCCCC	11.36	30266825
1380	Phosphorylation	PEHYVQETPLMFSRC CHHHCCCCCCCEECC	12.48	22199227
1385	Phosphorylation	QETPLMFSRCTSVSS CCCCCCEECCCCCHH	16.69	27732954
1388	Phosphorylation	PLMFSRCTSVSSLDS CCCEECCCCCHHHCC	30.93	22617229
1389	Phosphorylation	LMFSRCTSVSSLDSF CCEECCCCCHHHCCC	24.51	22199227
1391	Phosphorylation	FSRCTSVSSLDSFES EECCCCCHHHCCCHH	25.58	28348404
1392	Phosphorylation	SRCTSVSSLDSFESR ECCCCCHHHCCCHHC	33.76	23663014
1395	Phosphorylation	TSVSSLDSFESRSIA CCCHHHCCCHHCHHH	35.89	23663014
1398	Phosphorylation	SSLDSFESRSIASSV HHHCCCHHCHHHHHC	29.35	23663014
1426	Phosphorylation	SPSDLPDSPGQTMPP CHHHCCCCCCCCCCC	29.05	24719451
1436	Phosphorylation	QTMPPSRSKTPPPPP CCCCCCCCCCCCCCC	45.26	23401153
1438	Phosphorylation	MPPSRSKTPPPPPQT CCCCCCCCCCCCCCC	42.13	25159151
1445	Phosphorylation	TPPPPPQTAQTKREV CCCCCCCCCCCCCCC	26.89	23403867
1448	Phosphorylation	PPPQTAQTKREVPKN CCCCCCCCCCCCCCC	29.61	22817900
1459	Phosphorylation	VPKNKAPTAEKRESG CCCCCCCCHHHHCCC	52.92	22817900
1463	Methylation	KAPTAEKRESGPKQA CCCCHHHHCCCHHHH	34.51	-
1465	Phosphorylation	PTAEKRESGPKQAAV CCHHHHCCCHHHHHH	65.51	28176443
1501	Phosphorylation	ESTPDGFSCSSSLSA CCCCCCCCCCCCCCC	20.72	17910481
1503	Phosphorylation	TPDGFSCSSSLSALS CCCCCCCCCCCCCCC	23.05	17910481
1504	Phosphorylation	PDGFSCSSSLSALSL CCCCCCCCCCCCCCC	39.36	17910481
1505	Phosphorylation	DGFSCSSSLSALSLD CCCCCCCCCCCCCCC	15.28	17910481
1507	Phosphorylation	FSCSSSLSALSLDEP CCCCCCCCCCCCCCC	29.16	17910481
1510	Phosphorylation	SSSLSALSLDEPFIQ CCCCCCCCCCCCCCC	33.23	17910481
1537	Phosphorylation	ENDNGNETESEQPKE CCCCCCCCCCCCCCC	49.13	25627689
1539	Phosphorylation	DNGNETESEQPKESN CCCCCCCCCCCCCCC	49.29	26471730
1556	Phosphorylation	QEKEAEKTIDSEKDL HHHHHHHHCCHHHHH	22.86	21857030
1559	Phosphorylation	EAEKTIDSEKDLLDD HHHHHCCHHHHHCCC	42.57	21857030
1567	Phosphorylation	EKDLLDDSDDDDIEI HHHHCCCCCCCHHHH	42.48	20873877
1581	Phosphorylation	ILEECIISAMPTKSS HHHHHHHHHCCCCCC	9.90	28102081
1585	Phosphorylation	CIISAMPTKSSRKAK HHHHHCCCCCCCCCC	30.39	28102081
1610	Phosphorylation	PPVARKPSQLPVYKL CCCCCCCCCCCHHHC	47.59	30576142
1615	Phosphorylation	KPSQLPVYKLLPSQN CCCCCCHHHCCCCCC	8.25	27642862
1631	Phosphorylation	LQPQKHVSFTPGDDM CCCCCCCCCCCCCCC	24.11	26270265
1633	Phosphorylation	PQKHVSFTPGDDMPR CCCCCCCCCCCCCCC	20.89	25159151
1647	Phosphorylation	RVYCVEGTPINFSTA CEEEEECCCEECCCC	13.90	28102081
1652	Phosphorylation	EGTPINFSTATSLSD ECCCEECCCCCCHHH	16.79	28348404
1653	Phosphorylation	GTPINFSTATSLSDL CCCEECCCCCCHHHC	29.80	28348404
1655	Phosphorylation	PINFSTATSLSDLTI CEECCCCCCHHHCEE	30.23	28348404
1656	Phosphorylation	INFSTATSLSDLTIE EECCCCCCHHHCEEC	24.34	28348404
1658	Phosphorylation	FSTATSLSDLTIESP CCCCCCHHHCEECCC	30.27	28348404
1661	Phosphorylation	ATSLSDLTIESPPNE CCCHHHCEECCCCCC	27.91	28348404
1664	Phosphorylation	LSDLTIESPPNELAA HHHCEECCCCCCCCC	41.63	29507054
1681	Phosphorylation	GVRGGAQSGEFEKRD CCCCCCCCCCCCCCC	39.49	28985074
1706	O-linked_Glycosylation	EAQGGKTSSVTIPEL CCCCCCEEECCCCCC	26.71	OGP
1737	Phosphorylation	SAMPKGKSHKPFRVK HCCCCCCCCCCHHHH	45.47	-
1754	Phosphorylation	MDQVQQASASSSAPN HHHHHHHHHCCCCCC	25.09	29978859
1756	Phosphorylation	QVQQASASSSAPNKN HHHHHHHCCCCCCCC	23.48	29978859
1757	Phosphorylation	VQQASASSSAPNKNQ HHHHHHCCCCCCCCC	30.18	29978859
1758	Phosphorylation	QQASASSSAPNKNQL HHHHHCCCCCCCCCC	45.29	29978859
1773	Phosphorylation	DGKKKKPTSPVKPIP CCCCCCCCCCCCCCC	55.32	30266825
1774	Phosphorylation	GKKKKPTSPVKPIPQ CCCCCCCCCCCCCCC	35.90	30266825
1783	Phosphorylation	VKPIPQNTEYRTRVR CCCCCCCHHHHHHHH	29.19	30266825
1837	Phosphorylation	NEDRVRGSFAFDSPH CHHHCCCCCCCCCCC	11.66	23663014
1842	Phosphorylation	RGSFAFDSPHHYTPI CCCCCCCCCCCCCCC	21.49	23663014
1846	Phosphorylation	AFDSPHHYTPIEGTP CCCCCCCCCCCCCCC	15.92	23663014
1847	Phosphorylation	FDSPHHYTPIEGTPY CCCCCCCCCCCCCCC	17.27	23663014
1852	Phosphorylation	HYTPIEGTPYCFSRN CCCCCCCCCCCCCCC	9.78	23663014
1854	Phosphorylation	TPIEGTPYCFSRNDS CCCCCCCCCCCCCCC	13.13	23663014
1857	Phosphorylation	EGTPYCFSRNDSLSS CCCCCCCCCCCCCCC	26.98	23663014
1861	Phosphorylation	YCFSRNDSLSSLDFD CCCCCCCCCCCCCCC	33.43	30278072
1863	Phosphorylation	FSRNDSLSSLDFDDD CCCCCCCCCCCCCCC	32.57	25159151
1864	Phosphorylation	SRNDSLSSLDFDDDD CCCCCCCCCCCCCCC	36.93	25159151
1895	Phosphorylation	KESEAKVTSHTELTS HHCHHHCCCCCHHCC	17.68	28348404
1896	Phosphorylation	ESEAKVTSHTELTSN HCHHHCCCCCHHCCC	31.25	28348404
1898	Phosphorylation	EAKVTSHTELTSNQQ HHHCCCCCHHCCCCC	32.24	28348404
1906	Phosphorylation	ELTSNQQSANKTQAI HHCCCCCCCCHHHHH	24.85	25159151
1909	Acetylation	SNQQSANKTQAIAKQ CCCCCCCHHHHHHCC	41.55	26051181
1931	Phosphorylation	KPILQKQSTFPQSSK CCCCCCCCCCCCCCC	38.77	23312004
1932	Phosphorylation	PILQKQSTFPQSSKD CCCCCCCCCCCCCCC	36.52	30624053
1971	Phosphorylation	SHNSSLSSLSDIDQE CCCCCCCCCHHHCCC	36.87	-
1973	Phosphorylation	NSSLSSLSDIDQENN CCCCCCCHHHCCCCC	34.17	-
1995	Phosphorylation	KETEPPDSQGEPSKP CCCCCCCCCCCCCCC	45.95	18669648
2011	Phosphorylation	ASGYAPKSFHVEDTP CCCCCCCCCCCCCCC	21.37	21712546
2017	Phosphorylation	KSFHVEDTPVCFSRN CCCCCCCCCEEECCC	12.24	23663014
2022	Phosphorylation	EDTPVCFSRNSSLSS CCCCEEECCCCCCCC	25.98	25159151
2034	Phosphorylation	LSSLSIDSEDDLLQE CCCCCCCCHHHHHHH	41.05	22817900
2054	Phosphorylation	MPKKKKPSRLKGDNE CCCCCCCCCCCCCCC	60.16	22817900
2064	Phosphorylation	KGDNEKHSPRNMGGI CCCCCCCCCCCCCCC	36.30	26471730
2088	Phosphorylation	KDIQRPDSEHGLSPD HHCCCCCCCCCCCCC	33.89	23927012
2093	Phosphorylation	PDSEHGLSPDSENFD CCCCCCCCCCCCCCC	31.11	23401153
2096	Phosphorylation	EHGLSPDSENFDWKA CCCCCCCCCCCCHHH	37.51	23927012
2110	Phosphorylation	AIQEGANSIVSSLHQ HHHHHHHHHHHHHHH	24.67	25850435
2113	Phosphorylation	EGANSIVSSLHQAAA HHHHHHHHHHHHHHH	26.05	25850435
2114	Phosphorylation	GANSIVSSLHQAAAA HHHHHHHHHHHHHHH	20.98	25850435
2125	Phosphorylation	AAAAACLSRQASSDS HHHHHHHHHHCCCCC	23.41	25159151
2129	Phosphorylation	ACLSRQASSDSDSIL HHHHHHCCCCCCCCH	26.75	23401153
2130	Phosphorylation	CLSRQASSDSDSILS HHHHHCCCCCCCCHH	44.12	30266825
2132	Phosphorylation	SRQASSDSDSILSLK HHHCCCCCCCCHHHC	34.89	23663014
2134	Phosphorylation	QASSDSDSILSLKSG HCCCCCCCCHHHCCC	29.40	23663014
2137	Phosphorylation	SDSDSILSLKSGISL CCCCCCHHHCCCCCC	31.89	21406692
2140	Phosphorylation	DSILSLKSGISLGSP CCCHHHCCCCCCCCC	46.80	29978859
2143	Phosphorylation	LSLKSGISLGSPFHL HHHCCCCCCCCCCCC	30.15	25159151
2146	Phosphorylation	KSGISLGSPFHLTPD CCCCCCCCCCCCCCC	29.68	25159151
2151	Phosphorylation	LGSPFHLTPDQEEKP CCCCCCCCCCCCCCC	19.09	25159151
2160	Phosphorylation	DQEEKPFTSNKGPRI CCCCCCCCCCCCCCC	39.66	25002506
2161	Phosphorylation	QEEKPFTSNKGPRIL CCCCCCCCCCCCCCC	36.60	27732954
2174	Phosphorylation	ILKPGEKSTLETKKI CCCCCCCCCCEECCC	33.64	23403867
2175	Phosphorylation	LKPGEKSTLETKKIE CCCCCCCCCEECCCH	39.41	23403867
2183	Phosphorylation	LETKKIESESKGIKG CEECCCHHHCCCCCC	51.12	-
2185	Phosphorylation	TKKIESESKGIKGGK ECCCHHHCCCCCCCH	45.52	-
2189	Acetylation	ESESKGIKGGKKVYK HHHCCCCCCCHHHHH	70.99	7666049
2192	Acetylation	SKGIKGGKKVYKSLI CCCCCCCHHHHHHHH	47.97	7666061
2205	Phosphorylation	LITGKVRSNSEISGQ HHHCCCCCCCCCCCC	47.93	28985074
2207	Phosphorylation	TGKVRSNSEISGQMK HCCCCCCCCCCCCCC	37.24	30576142
2223	Phosphorylation	PLQANMPSISRGRTM CHHHCCCCCCCCCEE	23.56	28555341
2226	Methylation	ANMPSISRGRTMIHI HCCCCCCCCCEEEEC	36.62	-
2239	Phosphorylation	HIPGVRNSSSSTSPV ECCCCCCCCCCCCCC	22.49	20068231
2240	Phosphorylation	IPGVRNSSSSTSPVS CCCCCCCCCCCCCCC	31.68	20068231
2241	Phosphorylation	PGVRNSSSSTSPVSK CCCCCCCCCCCCCCC	37.14	23663014
2242	Phosphorylation	GVRNSSSSTSPVSKK CCCCCCCCCCCCCCC	34.55	23663014
2243	Phosphorylation	VRNSSSSTSPVSKKG CCCCCCCCCCCCCCC	38.71	23663014
2244	Phosphorylation	RNSSSSTSPVSKKGP CCCCCCCCCCCCCCC	25.83	20363803
2247	Phosphorylation	SSSTSPVSKKGPPLK CCCCCCCCCCCCCCC	31.84	20068231
2255	Phosphorylation	KKGPPLKTPASKSPS CCCCCCCCCCCCCCC	31.60	28176443
2258	Phosphorylation	PPLKTPASKSPSEGQ CCCCCCCCCCCCCCC	34.56	28176443
2260	Phosphorylation	LKTPASKSPSEGQTA CCCCCCCCCCCCCCC	31.03	29255136
2262	Phosphorylation	TPASKSPSEGQTATT CCCCCCCCCCCCCCC	62.54	29255136
2266	Phosphorylation	KSPSEGQTATTSPRG CCCCCCCCCCCCCCC	36.51	28176443
2268	Phosphorylation	PSEGQTATTSPRGAK CCCCCCCCCCCCCCC	31.06	25159151
2269	Phosphorylation	SEGQTATTSPRGAKP CCCCCCCCCCCCCCC	33.98	25159151
2270	Phosphorylation	EGQTATTSPRGAKPS CCCCCCCCCCCCCCC	14.30	25159151
2277	Phosphorylation	SPRGAKPSVKSELSP CCCCCCCCCCHHCCH	41.28	-
2280	Phosphorylation	GAKPSVKSELSPVAR CCCCCCCHHCCHHHH	41.43	23403867
2283	Phosphorylation	PSVKSELSPVARQTS CCCCHHCCHHHHHHC	17.18	23401153
2289	Phosphorylation	LSPVARQTSQIGGSS CCHHHHHHCCCCCCC	19.62	27282143
2290	Phosphorylation	SPVARQTSQIGGSSK CHHHHHHCCCCCCCC	16.09	23312004
2300	Phosphorylation	GGSSKAPSRSGSRDS CCCCCCCCCCCCCCC	43.89	24719451
2302	Phosphorylation	SSKAPSRSGSRDSTP CCCCCCCCCCCCCCC	45.52	25159151
2304	Phosphorylation	KAPSRSGSRDSTPSR CCCCCCCCCCCCCCC	33.87	23186163
2307	Phosphorylation	SRSGSRDSTPSRPAQ CCCCCCCCCCCCCCC	40.90	23312004
2308	Phosphorylation	RSGSRDSTPSRPAQQ CCCCCCCCCCCCCCC	29.58	25159151
2310	Phosphorylation	GSRDSTPSRPAQQPL CCCCCCCCCCCCCCC	51.49	23312004
2318	Phosphorylation	RPAQQPLSRPIQSPG CCCCCCCCCCCCCCC	42.57	25002506
2323	Phosphorylation	PLSRPIQSPGRNSIS CCCCCCCCCCCCCCC	30.00	30266825
2328	Phosphorylation	IQSPGRNSISPGRNG CCCCCCCCCCCCCCC	24.07	26425664
2330	Phosphorylation	SPGRNSISPGRNGIS CCCCCCCCCCCCCCC	22.56	20363803
2337	Phosphorylation	SPGRNGISPPNKLSQ CCCCCCCCCCCHHHC	35.39	20363803
2348	Phosphorylation	KLSQLPRTSSPSTAS HHHCCCCCCCCCCCC	31.45	20860994
2349	Phosphorylation	LSQLPRTSSPSTAST HHCCCCCCCCCCCCC	41.34	24719451
2350	Phosphorylation	SQLPRTSSPSTASTK HCCCCCCCCCCCCCC	23.43	28985074
2359	Phosphorylation	STASTKSSGSGKMSY CCCCCCCCCCCCCCC	38.24	24719451
2366	Phosphorylation	SGSGKMSYTSPGRQM CCCCCCCCCCCCCCC	14.03	26852163
2367	Phosphorylation	GSGKMSYTSPGRQMS CCCCCCCCCCCCCCC	22.57	25159151
2368	Phosphorylation	SGKMSYTSPGRQMSQ CCCCCCCCCCCCCCC	19.68	18669648
2374	Phosphorylation	TSPGRQMSQQNLTKQ CCCCCCCCCCCHHHH	21.92	25159151
2379	Phosphorylation	QMSQQNLTKQTGLSK CCCCCCHHHHHCCCC	28.76	29449344
2385	Phosphorylation	LTKQTGLSKNASSIP HHHHHCCCCCHHHCC	25.80	22468782
2389	Phosphorylation	TGLSKNASSIPRSES HCCCCCHHHCCCCHH	37.89	23403867
2390	Phosphorylation	GLSKNASSIPRSESA CCCCCHHHCCCCHHH	33.91	23403867
2394	Phosphorylation	NASSIPRSESASKGL CHHHCCCCHHHHHHH	30.46	30576142
2396	Phosphorylation	SSIPRSESASKGLNQ HHCCCCHHHHHHHHH	38.80	25849741
2398	Phosphorylation	IPRSESASKGLNQMN CCCCHHHHHHHHHHC	36.21	26074081
2420	Phosphorylation	KVELSRMSSTKSSGS CEEHHHCCCCCCCCC	33.47	20071362
2421	Phosphorylation	VELSRMSSTKSSGSE EEHHHCCCCCCCCCC	30.43	27273156
2422	Phosphorylation	ELSRMSSTKSSGSES EHHHCCCCCCCCCCC	27.86	29449344
2424	Phosphorylation	SRMSSTKSSGSESDR HHCCCCCCCCCCCCC	39.77	20363803
2425	Phosphorylation	RMSSTKSSGSESDRS HCCCCCCCCCCCCCC	48.14	27273156
2427	Phosphorylation	SSTKSSGSESDRSER CCCCCCCCCCCCCCC	35.56	20363803
2429	Phosphorylation	TKSSGSESDRSERPV CCCCCCCCCCCCCCE	39.77	20363803
2432	Phosphorylation	SGSESDRSERPVLVR CCCCCCCCCCCEEEE	42.84	20363803
2441	Phosphorylation	RPVLVRQSTFIKEAP CCEEEEECHHCCCCC	18.08	23403867
2442	Phosphorylation	PVLVRQSTFIKEAPS CEEEEECHHCCCCCC	22.50	23403867
2449	Phosphorylation	TFIKEAPSPTLRRKL HHCCCCCCHHHHHHH	37.25	30266825
2451	Phosphorylation	IKEAPSPTLRRKLEE CCCCCCHHHHHHHHH	36.92	30266825
2459	Phosphorylation	LRRKLEESASFESLS HHHHHHHHCCCCCCC	21.60	20363803
2461	Phosphorylation	RKLEESASFESLSPS HHHHHHCCCCCCCCC	38.53	30266825
2464	Phosphorylation	EESASFESLSPSSRP HHHCCCCCCCCCCCC	31.94	30266825
2466	Phosphorylation	SASFESLSPSSRPAS HCCCCCCCCCCCCCC	31.83	30266825
2468	Phosphorylation	SFESLSPSSRPASPT CCCCCCCCCCCCCCC	35.29	30266825
2469	Phosphorylation	FESLSPSSRPASPTR CCCCCCCCCCCCCCC	45.74	30266825
2473	Phosphorylation	SPSSRPASPTRSQAQ CCCCCCCCCCCCCCC	29.50	30266825
2475	Phosphorylation	SSRPASPTRSQAQTP CCCCCCCCCCCCCCC	40.22	30266825
2487	Phosphorylation	QTPVLSPSLPDMSLS CCCCCCCCCCCCCCC	49.51	28348404
2512	Phosphorylation	RKLPPNLSPTIEYND CCCCCCCCCCEEECC	27.00	25159151
2514	Phosphorylation	LPPNLSPTIEYNDGR CCCCCCCCEEECCCC	24.06	30576142
2517	Phosphorylation	NLSPTIEYNDGRPAK CCCCCEEECCCCCCH	18.07	23186163
2531	Phosphorylation	KRHDIARSHSESPSR HHHHHCCCCCCCCCC	23.49	22617229
2533	Phosphorylation	HDIARSHSESPSRLP HHHCCCCCCCCCCCC	40.80	23401153
2535	Phosphorylation	IARSHSESPSRLPIN HCCCCCCCCCCCCCC	31.06	23401153
2537	Phosphorylation	RSHSESPSRLPINRS CCCCCCCCCCCCCCC	56.58	26055452
2546	Phosphorylation	LPINRSGTWKREHSK CCCCCCCCCCCCCCC	29.12	24719451
2555	Phosphorylation	KREHSKHSSSLPRVS CCCCCCCCCCCCCEE	25.92	26699800
2556	Phosphorylation	REHSKHSSSLPRVST CCCCCCCCCCCCEEC	35.30	30576142
2557	Phosphorylation	EHSKHSSSLPRVSTW CCCCCCCCCCCEECC	45.46	30576142
2563	Phosphorylation	SSLPRVSTWRRTGSS CCCCCEECCCCCCCC	21.82	24719451
2567	Phosphorylation	RVSTWRRTGSSSSIL CEECCCCCCCCHHHH	32.61	23403867
2569	Phosphorylation	STWRRTGSSSSILSA ECCCCCCCCHHHHCC	26.83	25159151
2570	Phosphorylation	TWRRTGSSSSILSAS CCCCCCCCHHHHCCC	29.47	25159151
2571	Phosphorylation	WRRTGSSSSILSASS CCCCCCCHHHHCCCC	24.08	28450419
2572	Phosphorylation	RRTGSSSSILSASSE CCCCCCHHHHCCCCC	29.51	23090842
2575	Phosphorylation	GSSSSILSASSESSE CCCHHHHCCCCCCHH	25.16	23090842
2577	Phosphorylation	SSSILSASSESSEKA CHHHHCCCCCCHHHH	31.12	28985074
2578	Phosphorylation	SSILSASSESSEKAK HHHHCCCCCCHHHHH	41.01	23090842
2580	Phosphorylation	ILSASSESSEKAKSE HHCCCCCCHHHHHCC	45.83	23090842
2581	Phosphorylation	LSASSESSEKAKSED HCCCCCCHHHHHCCC	38.78	23090842
2586	Phosphorylation	ESSEKAKSEDEKHVN CCHHHHHCCCHHHHH	55.96	24719451
2594	Phosphorylation	EDEKHVNSISGTKQS CCHHHHHHCCCCCCC	19.62	22210691
2607	Phosphorylation	QSKENQVSAKGTWRK CCHHCCCCCCCCEEE	17.94	28509920
2611	Phosphorylation	NQVSAKGTWRKIKEN CCCCCCCCEEEHHHC	22.76	28509920
2621	O-linked_Glycosylation	KIKENEFSPTNSTSQ EHHHCCCCCCCCCCC	25.33	30059200
2621	Phosphorylation	KIKENEFSPTNSTSQ EHHHCCCCCCCCCCC	25.33	21815630
2623	Phosphorylation	KENEFSPTNSTSQTV HHCCCCCCCCCCCEE	40.37	22199227
2625	O-linked_Glycosylation	NEFSPTNSTSQTVSS CCCCCCCCCCCEECC	31.73	30059200
2625	Phosphorylation	NEFSPTNSTSQTVSS CCCCCCCCCCCEECC	31.73	30576142
2626	Phosphorylation	EFSPTNSTSQTVSSG CCCCCCCCCCEECCC	27.24	30576142
2627	Phosphorylation	FSPTNSTSQTVSSGA CCCCCCCCCEECCCC	24.55	21815630
2629	Phosphorylation	PTNSTSQTVSSGATN CCCCCCCEECCCCCC	23.32	28348404
2631	Phosphorylation	NSTSQTVSSGATNGA CCCCCEECCCCCCCH	26.83	20068231
2632	Phosphorylation	STSQTVSSGATNGAE CCCCEECCCCCCCHH	28.27	22210691
2635	Phosphorylation	QTVSSGATNGAESKT CEECCCCCCCHHCCE	37.40	22210691
2640	Phosphorylation	GATNGAESKTLIYQM CCCCCHHCCEEEECC	30.33	20068231
2645	Phosphorylation	AESKTLIYQMAPAVS HHCCEEEECCCCCCC	8.71	21945579
2652	Phosphorylation	YQMAPAVSKTEDVWV ECCCCCCCCCCCEEE	35.65	21945579
2671	Phosphorylation	CPINNPRSGRSPTGN CCCCCCCCCCCCCCC	39.55	23401153
2674	Phosphorylation	NNPRSGRSPTGNTPP CCCCCCCCCCCCCCC	30.27	29255136
2676	Phosphorylation	PRSGRSPTGNTPPVI CCCCCCCCCCCCCCC	44.29	30266825
2679	Phosphorylation	GRSPTGNTPPVIDSV CCCCCCCCCCCCCCH	30.25	30266825
2685	Phosphorylation	NTPPVIDSVSEKANP CCCCCCCCHHHHCCC	19.20	30576142
2687	Phosphorylation	PPVIDSVSEKANPNI CCCCCCHHHHCCCCC	37.01	23927012
2710	Phosphorylation	KQNVGNGSVPMRTVG HHHCCCCCCCCCCCC	27.35	-
2724	Phosphorylation	GLENRLNSFIQVDAP CCHHHHCCCEEECCC	28.46	30266825
2749	O-linked_Glycosylation	QNNPVPVSETNESSI CCCCCCCCCCCCCCC	32.41	30059200
2754	Phosphorylation	PVSETNESSIVERTP CCCCCCCCCCCCCCC	27.68	28555341
2755	Phosphorylation	VSETNESSIVERTPF CCCCCCCCCCCCCCC	25.19	28555341
2760	Phosphorylation	ESSIVERTPFSSSSS CCCCCCCCCCCCCCC	18.38	25002506
2763	Phosphorylation	IVERTPFSSSSSSKH CCCCCCCCCCCCCCC	30.43	26434776
2764	Phosphorylation	VERTPFSSSSSSKHS CCCCCCCCCCCCCCC	34.32	25159151
2765	Phosphorylation	ERTPFSSSSSSKHSS CCCCCCCCCCCCCCC	32.80	25159151
2766	Phosphorylation	RTPFSSSSSSKHSSP CCCCCCCCCCCCCCC	40.35	25159151
2767	Phosphorylation	TPFSSSSSSKHSSPS CCCCCCCCCCCCCCC	45.41	25159151
2768	Phosphorylation	PFSSSSSSKHSSPSG CCCCCCCCCCCCCCC	36.01	28985074
2771	Phosphorylation	SSSSSKHSSPSGTVA CCCCCCCCCCCCCEE	47.91	30266825
2772	Phosphorylation	SSSSKHSSPSGTVAA CCCCCCCCCCCCEEE	23.86	30266825
2774	Phosphorylation	SSKHSSPSGTVAARV CCCCCCCCCCEEEEE	49.39	22496350
2776	Phosphorylation	KHSSPSGTVAARVTP CCCCCCCCEEEEECC	16.00	21712546
2782	Phosphorylation	GTVAARVTPFNYNPS CCEEEEECCCCCCCC	19.33	25159151
2786	Phosphorylation	ARVTPFNYNPSPRKS EEECCCCCCCCCCCC	28.91	23312004
2789	Phosphorylation	TPFNYNPSPRKSSAD CCCCCCCCCCCCCCC	33.43	9731533
2793	Phosphorylation	YNPSPRKSSADSTSA CCCCCCCCCCCCCCC	31.85	22496350
2794	Phosphorylation	NPSPRKSSADSTSAR CCCCCCCCCCCCCCC	38.85	22496350
2797	Phosphorylation	PRKSSADSTSARPSQ CCCCCCCCCCCCHHH	24.79	20068231
2798	Phosphorylation	RKSSADSTSARPSQI CCCCCCCCCCCHHHC	27.27	20068231
2799	Phosphorylation	KSSADSTSARPSQIP CCCCCCCCCCHHHCC	26.66	20068231
2803	Phosphorylation	DSTSARPSQIPTPVN CCCCCCHHHCCCCCC	34.88	23927012
2807	Phosphorylation	ARPSQIPTPVNNNTK CCHHHCCCCCCCCCC	41.31	25159151
2818	Phosphorylation	NNTKKRDSKTDSTES CCCCCCCCCCCCCCC	41.30	24719451
2820	Phosphorylation	TKKRDSKTDSTESSG CCCCCCCCCCCCCCC	38.85	28122231
2822	Phosphorylation	KRDSKTDSTESSGTQ CCCCCCCCCCCCCCC	39.03	28122231
2823	Phosphorylation	RDSKTDSTESSGTQS CCCCCCCCCCCCCCC	42.57	28122231
2825	Phosphorylation	SKTDSTESSGTQSPK CCCCCCCCCCCCCCC	33.87	21712546
2826	Phosphorylation	KTDSTESSGTQSPKR CCCCCCCCCCCCCCC	39.36	23312004
2828	Phosphorylation	DSTESSGTQSPKRHS CCCCCCCCCCCCCCC	28.02	29743597
2830	Phosphorylation	TESSGTQSPKRHSGS CCCCCCCCCCCCCCC	32.02	25849741
2835	Phosphorylation	TQSPKRHSGSYLVTS CCCCCCCCCCEEEEC	33.20	30266825
2837	Phosphorylation	SPKRHSGSYLVTSV- CCCCCCCCEEEECC-	20.50	30266825
2838	Phosphorylation	PKRHSGSYLVTSV-- CCCCCCCEEEECC--	14.55	23927012
2841	Phosphorylation	HSGSYLVTSV----- CCCCEEEECC-----	22.60	23927012
2842	Phosphorylation	SGSYLVTSV------ CCCEEEECC------	20.53	26055452

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1279	S	Phosphorylation	Kinase	CK1_GROUP	-	PhosphoELM
1279	S	Phosphorylation	Kinase	CK1-FAMILY	-	GPS
1279	S	Phosphorylation	Kinase	CSNK1E	P49674	GPS
1360	S	Phosphorylation	Kinase	CDK2	P24941	PSP
1392	S	Phosphorylation	Kinase	CK1_GROUP	-	PhosphoELM
1392	S	Phosphorylation	Kinase	CK1-FAMILY	-	GPS
1392	S	Phosphorylation	Kinase	CSNK1E	P49674	GPS
1501	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
1501	S	Phosphorylation	Kinase	GSK-FAMILY	-	GPS
1503	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
1503	S	Phosphorylation	Kinase	GSK-FAMILY	-	GPS
1504	S	Phosphorylation	Kinase	CSNK1A1	P48729	GPS
1504	S	Phosphorylation	Kinase	CK1-FAMILY	-	GPS
1504	S	Phosphorylation	Kinase	CSNK1G1	Q9HCP0	GPS
1504	S	Phosphorylation	Kinase	CSNK1D	P48730	GPS
1505	S	Phosphorylation	Kinase	CSNK1G1	Q9HCP0	GPS
1505	S	Phosphorylation	Kinase	CSNK1A1	P48729	GPS
1505	S	Phosphorylation	Kinase	CK1-FAMILY	-	GPS
1505	S	Phosphorylation	Kinase	CSNK1D	P48730	GPS
1507	S	Phosphorylation	Kinase	CSNK1G1	Q9HCP0	GPS
1507	S	Phosphorylation	Kinase	CK1-FAMILY	-	GPS
1507	S	Phosphorylation	Kinase	CSNK1D	P48730	GPS
1507	S	Phosphorylation	Kinase	CSNK1A1	P48729	GPS
1510	S	Phosphorylation	Kinase	CSNK1G1	Q9HCP0	GPS
1510	S	Phosphorylation	Kinase	CSNK1D	P48730	GPS
1510	S	Phosphorylation	Kinase	CK1-FAMILY	-	GPS
1510	S	Phosphorylation	Kinase	CSNK1A1	P48729	GPS
2054	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
2054	S	Phosphorylation	Kinase	PKA_GROUP	-	PhosphoELM

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of APC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of APC_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CTNA1_HUMAN	CTNNA1	physical	8259519
CTNB1_HUMAN	CTNNB1	physical	8259519
MUC1_HUMAN	MUC1	physical	15020226
2A5A_HUMAN	PPP2R5A	physical	11585828
TBA4A_HUMAN	TUBA4A	physical	11166179
XPO1_HUMAN	XPO1	physical	12070164
APC_HUMAN	APC	physical	8389242
AP2A_HUMAN	TFAP2A	physical	15331612
MARE2_HUMAN	MAPRE2	physical	7606712
CSK21_HUMAN	CSNK2A1	physical	11972058
CSK2B_HUMAN	CSNK2B	physical	11972058
AXIN1_HUMAN	AXIN1	physical	9734785
APC_HUMAN	APC	physical	12070164
CTNB1_HUMAN	CTNNB1	physical	11972058
CTNB1_HUMAN	CTNNB1	physical	12628243
CTNA1_HUMAN	CTNNA1	physical	7651399
CTNB1_HUMAN	CTNNB1	physical	11251183
DLG3_HUMAN	DLG3	physical	9188857
PLAK_HUMAN	JUP	physical	7651399
KIFA3_HUMAN	KIFAP3	physical	11912492
SIAH1_HUMAN	SIAH1	physical	11389840
MARE1_HUMAN	MAPRE1	physical	12388762
DLGP1_HUMAN	DLGAP1	physical	9286858
CTNB1_HUMAN	CTNNB1	physical	9286858
CTNB1_HUMAN	CTNNB1	physical	16510874
ACTN1_HUMAN	ACTN1	physical	20936779
AP2B1_HUMAN	AP2B1	physical	20936779
ANXA7_HUMAN	ANXA7	physical	20936779
DYST_HUMAN	DST	physical	20936779
CO4A_HUMAN	C4A	physical	20936779
CBP_HUMAN	CREBBP	physical	20936779
CTNA1_HUMAN	CTNNA1	physical	20936779
EPAS1_HUMAN	EPAS1	physical	20936779
FLNA_HUMAN	FLNA	physical	20936779
GOGA2_HUMAN	GOLGA2	physical	20936779
AGFG1_HUMAN	AGFG1	physical	20936779
GRP78_HUMAN	HSPA5	physical	20936779
PLAK_HUMAN	JUP	physical	20936779
KINH_HUMAN	KIF5B	physical	20936779
K2C5_HUMAN	KRT5	physical	20936779
K1C13_HUMAN	KRT13	physical	20936779
K1C14_HUMAN	KRT14	physical	20936779
K1C15_HUMAN	KRT15	physical	20936779
K1C17_HUMAN	KRT17	physical	20936779
K1C19_HUMAN	KRT19	physical	20936779
LAMA3_HUMAN	LAMA3	physical	20936779
LAMA4_HUMAN	LAMA4	physical	20936779
NU4M_HUMAN	ND4	physical	20936779
MYH10_HUMAN	MYH10	physical	20936779
MYH11_HUMAN	MYH11	physical	20936779
MYO6_HUMAN	MYO6	physical	20936779
HNRPM_HUMAN	HNRNPM	physical	20936779
NEBU_HUMAN	NEB	physical	20936779
NUP98_HUMAN	NUP98	physical	20936779
PSMD1_HUMAN	PSMD1	physical	20936779
RBP2_HUMAN	RANBP2	physical	20936779
RS27_HUMAN	RPS27	physical	20936779
SPTB2_HUMAN	SPTBN1	physical	20936779
SPTN2_HUMAN	SPTBN2	physical	20936779
RO52_HUMAN	TRIM21	physical	20936779
TAF1_HUMAN	TAF1	physical	20936779
TPR_HUMAN	TPR	physical	20936779
NU214_HUMAN	NUP214	physical	20936779
GANP_HUMAN	MCM3AP	physical	20936779
SMC3_HUMAN	SMC3	physical	20936779
HGS_HUMAN	HGS	physical	20936779
CYH2_HUMAN	CYTH2	physical	20936779
NUP58_HUMAN	NUPL1	physical	20936779
SETB1_HUMAN	SETDB1	physical	20936779
P121A_HUMAN	POM121	physical	20936779
NU153_HUMAN	NUP153	physical	20936779
RANB9_HUMAN	RANBP9	physical	20936779
COG5_HUMAN	COG5	physical	20936779
NUPL2_HUMAN	NUPL2	physical	20936779
AGRL1_HUMAN	LPHN1	physical	20936779
SC31A_HUMAN	SEC31A	physical	20936779
U520_HUMAN	SNRNP200	physical	20936779
SYNE1_HUMAN	SYNE1	physical	20936779
ASPP1_HUMAN	PPP1R13B	physical	20936779
CYTSA_HUMAN	SPECC1L	physical	20936779
MACF1_HUMAN	MACF1	physical	20936779
COG4_HUMAN	COG4	physical	20936779
PNISR_HUMAN	PNISR	physical	20936779
K1C23_HUMAN	KRT23	physical	20936779
ANR17_HUMAN	ANKRD17	physical	20936779
GGYF2_HUMAN	GIGYF2	physical	20936779
FHOD1_HUMAN	FHOD1	physical	20936779
NUP54_HUMAN	NUP54	physical	20936779
MBD5_HUMAN	MBD5	physical	20936779
ERBIN_HUMAN	ERBB2IP	physical	20936779
F214A_HUMAN	FAM214A	physical	20936779
K1328_HUMAN	KIAA1328	physical	20936779
ZN106_HUMAN	ZNF106	physical	20936779
RBM4B_HUMAN	RBM4B	physical	20936779
FBX30_HUMAN	FBXO30	physical	20936779
ING5_HUMAN	ING5	physical	20936779
CGNL1_HUMAN	CGNL1	physical	20936779
NAV3_HUMAN	NAV3	physical	20936779
NAV1_HUMAN	NAV1	physical	20936779
NAV2_HUMAN	NAV2	physical	20936779
NOSTN_HUMAN	NOSTRIN	physical	20936779
NCK5L_HUMAN	NCKAP5L	physical	20936779
NCKP5_HUMAN	NCKAP5	physical	20936779
CTNB1_HUMAN	CTNNB1	physical	15355978
CTBP1_HUMAN	CTBP1	physical	16510875
ZRAN1_HUMAN	ZRANB1	physical	18281465
CTNB1_HUMAN	CTNNB1	physical	21664290
PCNA_HUMAN	PCNA	physical	21664290
RFA2_HUMAN	RPA2	physical	21664290
STRN_HUMAN	STRN	physical	18502210
STRN3_HUMAN	STRN3	physical	18502210
STRN4_HUMAN	STRN4	physical	18502210
TNKS1_HUMAN	TNKS	physical	23277359
HECD1_HUMAN	HECTD1	physical	23277359
RN146_HUMAN	RNF146	physical	23277359
AXIN1_HUMAN	AXIN1	physical	23277359
CTBP1_HUMAN	CTBP1	physical	15525529
CTNB1_HUMAN	CTNNB1	physical	15525529
CTNB1_HUMAN	CTNNB1	physical	23840886
CTNB1_HUMAN	CTNNB1	physical	10545404
AGR3_HUMAN	AGR3	physical	25640309
CASC3_HUMAN	CASC3	physical	25640309
CCL5_HUMAN	CCL5	physical	25640309
CP17A_HUMAN	CYP17A1	physical	25640309
DIRA3_HUMAN	DIRAS3	physical	25640309
DKK3_HUMAN	DKK3	physical	25640309
HXC6_HUMAN	HOXC6	physical	25640309
IL24_HUMAN	IL24	physical	25640309
ARY2_HUMAN	NAT2	physical	25640309
PDLI2_HUMAN	PDLIM2	physical	25640309
ST14_HUMAN	ST14	physical	25640309
TFF1_HUMAN	TFF1	physical	25640309
TRI25_HUMAN	TRIM25	physical	25640309
CTBP1_HUMAN	CTBP1	physical	26496610
CTNA1_HUMAN	CTNNA1	physical	26496610
CTNB1_HUMAN	CTNNB1	physical	26496610
DVL2_HUMAN	DVL2	physical	26496610
EF1D_HUMAN	EEF1D	physical	26496610
MARK2_HUMAN	MARK2	physical	26496610
PLAK_HUMAN	JUP	physical	26496610
PKP2_HUMAN	PKP2	physical	26496610
AXIN1_HUMAN	AXIN1	physical	26496610
MD1L1_HUMAN	MAD1L1	physical	26496610
MBD4_HUMAN	MBD4	physical	26496610
TELO2_HUMAN	TELO2	physical	26496610
AKP13_HUMAN	AKAP13	physical	26496610
RFOX2_HUMAN	RBFOX2	physical	26496610
RM18_HUMAN	MRPL18	physical	26496610
SENP1_HUMAN	SENP1	physical	26496610
BBX_HUMAN	BBX	physical	26496610
RHG21_HUMAN	ARHGAP21	physical	26496610
WIZ_HUMAN	WIZ	physical	26496610
SAV1_HUMAN	SAV1	physical	26496610
AMER1_HUMAN	AMER1	physical	26496610
FA83B_HUMAN	FAM83B	physical	26496610
KC1E_HUMAN	CSNK1E	physical	25241761
CTNB1_HUMAN	CTNNB1	physical	25241761
CTNA1_HUMAN	CTNNA1	physical	25241761
SIAH1_HUMAN	SIAH1	physical	25241761
CSK21_HUMAN	CSNK2A1	physical	25241761
CDK9_HUMAN	CDK9	genetic	28319113
VHL_HUMAN	VHL	genetic	28319113
SNF5_HUMAN	SMARCB1	genetic	28319113
UBR5_HUMAN	UBR5	physical	18076571
CTNB1_HUMAN	CTNNB1	physical	29045831
FBW1A_HUMAN	BTRC	physical	29045831
GSK3B_HUMAN	GSK3B	physical	29045831
CTNA1_HUMAN	CTNNA1	physical	29045831
KC1E_HUMAN	CSNK1E	physical	29045831
KC1D_HUMAN	CSNK1D	physical	29045831
UBP7_HUMAN	USP7	physical	29045831
UBP30_HUMAN	USP30	physical	29045831
RN114_HUMAN	RNF114	physical	29045831
RO52_HUMAN	TRIM21	physical	29045831
ZFP91_HUMAN	ZFP91	physical	29045831
RBP2_HUMAN	RANBP2	physical	29045831
TRI32_HUMAN	TRIM32	physical	29045831
CTNB1_MOUSE	Ctnnb1	physical	29045831
CTNA1_MOUSE	Ctnna1	physical	29045831
KC1E_MOUSE	Csnk1e	physical	29045831
KC1D_MOUSE	Csnk1d	physical	29045831
UBP7_MOUSE	Usp7	physical	29045831

Drug and Disease Associations

• Kegg Disease
• H00017: Esophageal cancer
• H00018: Gastric cancer
• H00044: Cancer of the anal canal
• H00047: Gallbladder cancer
• H01025: Familial adenomatous polyposis
• OMIM Disease
• 175100: Familial adenomatous polyposis (FAP)
• 135290: Hereditary desmoid disease (HDD)
• 155255: Medulloblastoma (MDB)
• 276300: Mismatch repair cancer syndrome (MMRCS)
• 613659: Gastric cancer (GASC)
• 114550: Hepatocellular carcinoma (HCC)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-987; THR-1438; SER-2260;THR-2266 AND SER-2270, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-780; SER-1042; SER-1360;SER-1861; SER-1863; SER-1864; SER-2088; SER-2093; SER-2096; SER-2143;THR-2151; SER-2260; SER-2270; SER-2283; SER-2464; SER-2469; SER-2473;SER-2533; SER-2535; SER-2671; SER-2674; THR-2679 AND SER-2789, ANDMASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2125; SER-2671;SER-2674; THR-2676; SER-2789; SER-2835; SER-2837 AND TYR-2838, ANDMASS SPECTROMETRY.
PubMed: 18220336

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2283, AND MASSSPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1861; SER-1863; SER-1864AND SER-2398, AND MASS SPECTROMETRY.
PubMed: 17081983