dbPTM

PKP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PKP2_HUMAN
UniProt AC	Q99959
Protein Name	Plakophilin-2
Gene Name	PKP2
Organism	Homo sapiens (Human).
Sequence Length	881
Subcellular Localization	Nucleus . Cell junction, desmosome . Nuclear and associated with desmosomes.
Protein Description	May play a role in junctional plaques..
Protein Sequence	MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	APGAPAEYGYIRTVL CCCCCCHHCHHHHHH	19.82	25394399
12	Phosphorylation	GAPAEYGYIRTVLGQ CCCCHHCHHHHHHHH	6.07	25106551
27	Phosphorylation	QILGQLDSSSLALPS HHHCCCCCCCCCCCC	30.34	28348404
28	Phosphorylation	ILGQLDSSSLALPSE HHCCCCCCCCCCCCC	29.10	28348404
29	Phosphorylation	LGQLDSSSLALPSEA HCCCCCCCCCCCCCC	22.93	24719451
37	Ubiquitination	LALPSEAKLKLAGSS CCCCCCCCEEECCCC	41.94	21906983
37	Ubiquitination	LALPSEAKLKLAGSS CCCCCCCCEEECCCC	41.94	21906983
37 (in isoform 1)	Ubiquitination	-	41.94	21906983
37 (in isoform 2)	Ubiquitination	-	41.94	21906983
39	Methylation	LPSEAKLKLAGSSGR CCCCCCEEECCCCCC	35.27	24639879
39	Ubiquitination	LPSEAKLKLAGSSGR CCCCCCEEECCCCCC	35.27	22817900
43	Phosphorylation	AKLKLAGSSGRGGQT CCEEECCCCCCCCCC	24.82	20068231
44	Phosphorylation	KLKLAGSSGRGGQTV CEEECCCCCCCCCCC	31.43	20068231
46	Methylation	KLAGSSGRGGQTVKS EECCCCCCCCCCCHH	48.28	24129315
50	Phosphorylation	SSGRGGQTVKSLRIQ CCCCCCCCCHHHHHH	32.93	29514088
52	Methylation	GRGGQTVKSLRIQEQ CCCCCCCHHHHHHHH	47.35	21675381
52	Ubiquitination	GRGGQTVKSLRIQEQ CCCCCCCHHHHHHHH	47.35	29967540
53	Phosphorylation	RGGQTVKSLRIQEQV CCCCCCHHHHHHHHH	20.67	25056879
63	Phosphorylation	IQEQVQQTLARKGRS HHHHHHHHHHHCCCC	12.80	30576142
70	Phosphorylation	TLARKGRSSVGNGNL HHHHCCCCCCCCCCC	37.74	26657352
71	Phosphorylation	LARKGRSSVGNGNLH HHHCCCCCCCCCCCC	32.46	25159151
80	Phosphorylation	GNGNLHRTSSVPEYV CCCCCCCCCCCCHHH	18.01	23927012
81	Phosphorylation	NGNLHRTSSVPEYVY CCCCCCCCCCCHHHE	29.33	23927012
82	Phosphorylation	GNLHRTSSVPEYVYN CCCCCCCCCCHHHEE	40.87	28355574
86	Phosphorylation	RTSSVPEYVYNLHLV CCCCCCHHHEEEEEE	11.36	23927012
88	Phosphorylation	SSVPEYVYNLHLVEN CCCCHHHEEEEEEEC	15.88	23927012
102	Phosphorylation	NDFVGGRSPVPKTYD CCCCCCCCCCCCHHH	33.26	25159151
106	Ubiquitination	GGRSPVPKTYDMLKA CCCCCCCCHHHHHHC	61.01	23503661
107	Phosphorylation	GRSPVPKTYDMLKAG CCCCCCCHHHHHHCC	20.77	23663014
108	Phosphorylation	RSPVPKTYDMLKAGT CCCCCCHHHHHHCCC	12.89	23663014
112	Ubiquitination	PKTYDMLKAGTTATY CCHHHHHHCCCEEEE	37.83	21906983
112	Methylation	PKTYDMLKAGTTATY CCHHHHHHCCCEEEE	37.83	21688109
112	Ubiquitination	PKTYDMLKAGTTATY CCHHHHHHCCCEEEE	37.83	21906983
112 (in isoform 1)	Ubiquitination	-	37.83	21906983
112 (in isoform 2)	Ubiquitination	-	37.83	21906983
115	Phosphorylation	YDMLKAGTTATYEGR HHHHHCCCEEEECCC	20.37	23663014
116	Phosphorylation	DMLKAGTTATYEGRW HHHHCCCEEEECCCC	18.98	23663014
118	Phosphorylation	LKAGTTATYEGRWGR HHCCCEEEECCCCCC	21.73	21945579
119	Phosphorylation	KAGTTATYEGRWGRG HCCCEEEECCCCCCC	17.58	21945579
125	Methylation	TYEGRWGRGTAQYSS EECCCCCCCCCCCCC	32.12	30760701
127	Phosphorylation	EGRWGRGTAQYSSQK CCCCCCCCCCCCCCC	14.82	23927012
130	Phosphorylation	WGRGTAQYSSQKSVE CCCCCCCCCCCCCHH	14.07	21945579
131	Phosphorylation	GRGTAQYSSQKSVEE CCCCCCCCCCCCHHH	17.76	21945579
132	Phosphorylation	RGTAQYSSQKSVEER CCCCCCCCCCCHHHH	36.37	21945579
134	Ubiquitination	TAQYSSQKSVEERSL CCCCCCCCCHHHHHH	59.42	21906983
134	Ubiquitination	TAQYSSQKSVEERSL CCCCCCCCCHHHHHH	59.42	22817900
134 (in isoform 1)	Ubiquitination	-	59.42	21906983
134 (in isoform 2)	Ubiquitination	-	59.42	21906983
135	Phosphorylation	AQYSSQKSVEERSLR CCCCCCCCHHHHHHH	27.42	23927012
140	Phosphorylation	QKSVEERSLRHPLRR CCCHHHHHHHCCHHH	32.79	24719451
151	Phosphorylation	PLRRLEISPDSSPER CHHHCCCCCCCCCCH	17.18	19664994
154	Phosphorylation	RLEISPDSSPERAHY HCCCCCCCCCCHHHC	51.69	23927012
155	Phosphorylation	LEISPDSSPERAHYT CCCCCCCCCCHHHCC	37.85	23927012
161	Phosphorylation	SSPERAHYTHSDYQY CCCCHHHCCCCCCCC	12.74	21945579
162	Phosphorylation	SPERAHYTHSDYQYS CCCHHHCCCCCCCCC	12.68	21945579
164	Phosphorylation	ERAHYTHSDYQYSQR CHHHCCCCCCCCCCH	30.16	21945579
166	Phosphorylation	AHYTHSDYQYSQRSQ HHCCCCCCCCCCHHC	16.62	21945579
168	Phosphorylation	YTHSDYQYSQRSQAG CCCCCCCCCCHHCCC	10.67	21945579
169	Phosphorylation	THSDYQYSQRSQAGH CCCCCCCCCHHCCCC	12.00	21945579
172	Phosphorylation	DYQYSQRSQAGHTLH CCCCCCHHCCCCCCC	19.42	28355574
177	Phosphorylation	QRSQAGHTLHHQESR CHHCCCCCCCCHHHH	27.20	23663014
183	Phosphorylation	HTLHHQESRRAALLV CCCCCHHHHCHHEEC	22.09	28355574
194	Phosphorylation	ALLVPPRYARSEIVG HEECCCCHHHCCEEE	16.49	23927012
197	Phosphorylation	VPPRYARSEIVGVSR CCCCHHHCCEEEEEC	24.41	28355574
203	Phosphorylation	RSEIVGVSRAGTTSR HCCEEEEECCCCCCC	15.52	28355574
204	Methylation	SEIVGVSRAGTTSRQ CCEEEEECCCCCCCH	34.33	115487731
207	Phosphorylation	VGVSRAGTTSRQRHF EEEECCCCCCCHHCC	22.18	23911959
208	Phosphorylation	GVSRAGTTSRQRHFD EEECCCCCCCHHCCH	22.46	-
216	Phosphorylation	SRQRHFDTYHRQYQH CCHHCCHHCCHHHHC	21.93	28152594
217	Phosphorylation	RQRHFDTYHRQYQHG CHHCCHHCCHHHHCC	9.24	20007894
221	Phosphorylation	FDTYHRQYQHGSVSD CHHCCHHHHCCCCCC	11.48	23090842
225	Phosphorylation	HRQYQHGSVSDTVFD CHHHHCCCCCCCCCC	19.14	26657352
227	Phosphorylation	QYQHGSVSDTVFDSI HHHCCCCCCCCCCCC	29.30	28857561
229	Phosphorylation	QHGSVSDTVFDSIPA HCCCCCCCCCCCCCC	18.63	26657352
233	Phosphorylation	VSDTVFDSIPANPAL CCCCCCCCCCCCCHH	21.00	23090842
242	Phosphorylation	PANPALLTYPRPGTS CCCCHHCCCCCCCCC	32.12	23090842
243	Phosphorylation	ANPALLTYPRPGTSR CCCHHCCCCCCCCCC	9.38	26657352
248	Phosphorylation	LTYPRPGTSRSMGNL CCCCCCCCCCCHHHH	24.53	28857561
249	Phosphorylation	TYPRPGTSRSMGNLL CCCCCCCCCCHHHHH	28.42	28857561
251	Phosphorylation	PRPGTSRSMGNLLEK CCCCCCCCHHHHHHH	30.70	19664994
258	Ubiquitination	SMGNLLEKENYLTAG CHHHHHHHCCEECCC	51.75	21906983
258	Ubiquitination	SMGNLLEKENYLTAG CHHHHHHHCCEECCC	51.75	22817900
258 (in isoform 1)	Ubiquitination	-	51.75	21906983
258 (in isoform 2)	Ubiquitination	-	51.75	21906983
261	Phosphorylation	NLLEKENYLTAGLTV HHHHHCCEECCCCEE	13.40	21082442
263	Phosphorylation	LEKENYLTAGLTVGQ HHHCCEECCCCEECC	14.33	26356563
267	Phosphorylation	NYLTAGLTVGQVRPL CEECCCCEECCEECC	22.98	-
281	Phosphorylation	LVPLQPVTQNRASRS CCCCCCCCCCCCCCC	27.15	24719451
286	Phosphorylation	PVTQNRASRSSWHQS CCCCCCCCCCCCCHH	29.47	28152594
288	Phosphorylation	TQNRASRSSWHQSSF CCCCCCCCCCCHHHH	34.97	23927012
289	Phosphorylation	QNRASRSSWHQSSFH CCCCCCCCCCHHHHH	27.71	28355574
293	Phosphorylation	SRSSWHQSSFHSTRT CCCCCCHHHHHCCCH	23.29	23927012
294	Phosphorylation	RSSWHQSSFHSTRTL CCCCCHHHHHCCCHH	22.02	28355574
297	Phosphorylation	WHQSSFHSTRTLREA CCHHHHHCCCHHHHH	19.99	28355574
298	Phosphorylation	HQSSFHSTRTLREAG CHHHHHCCCHHHHHC	21.07	30206219
300	Phosphorylation	SSFHSTRTLREAGPS HHHHCCCHHHHHCCC	30.20	23927012
302	Methylation	FHSTRTLREAGPSVA HHCCCHHHHHCCCEE	30.98	81452661
307	Phosphorylation	TLREAGPSVAVDSSG HHHHHCCCEEECCCC	23.07	28857561
312	Phosphorylation	GPSVAVDSSGRRAHL CCCEEECCCCCEEEE	28.26	30266825
313	Phosphorylation	PSVAVDSSGRRAHLT CCEEECCCCCEEEEE	31.68	30266825
320	Phosphorylation	SGRRAHLTVGQAAAG CCCEEEEEEECCCCC	16.84	23403867
329	Phosphorylation	GQAAAGGSGNLLTER ECCCCCCCCCCCCCC	24.48	20031617
334	Phosphorylation	GGSGNLLTERSTFTD CCCCCCCCCCCCCCH	32.30	30266825
337	Phosphorylation	GNLLTERSTFTDSQL CCCCCCCCCCCHHHC	22.95	20860994
340	Phosphorylation	LTERSTFTDSQLGNA CCCCCCCCHHHCCCC	34.53	27794612
342	Phosphorylation	ERSTFTDSQLGNADM CCCCCCHHHCCCCCH	25.01	26657352
352	Phosphorylation	GNADMEMTLERAVSM CCCCHHHHHHHHHHH	16.50	27794612
358	Phosphorylation	MTLERAVSMLEADHM HHHHHHHHHHHHHHC	19.37	28857561
390	Dimethylation	QKSEARKRVNQLRGI CHHHHHHHHHHHHHH	27.37	-
390	Methylation	QKSEARKRVNQLRGI CHHHHHHHHHHHHHH	27.37	115372705
395	Dimethylation	RKRVNQLRGILKLLQ HHHHHHHHHHHHHHH	21.97	-
395	Methylation	RKRVNQLRGILKLLQ HHHHHHHHHHHHHHH	21.97	115372711
405	Ubiquitination	LKLLQLLKVQNEDVQ HHHHHHHHCCCHHHH	50.82	21906983
405	Ubiquitination	LKLLQLLKVQNEDVQ HHHHHHHHCCCHHHH	50.82	21906983
405	Ubiquitination	LKLLQLLKVQNEDVQ HHHHHHHHCCCHHHH	50.82	22817900
405 (in isoform 1)	Ubiquitination	-	50.82	21906983
405 (in isoform 2)	Ubiquitination	-	50.82	21906983
430	Ubiquitination	VFEDNDNKLEVAELN HEECCCCCEEHHHHC	49.22	29967540
447	Ubiquitination	PRLLQVLKQTRDLET HHHHHHHHHCCCCCH	51.25	29967540
459	Phosphorylation	LETKKQITDHTVNLR CCHHHHCCCCCCCCH	21.16	-
462	Phosphorylation	KKQITDHTVNLRSRN HHHCCCCCCCCHHCC	17.56	-
466 (in isoform 2)	Phosphorylation	-	28.50	22210691
467 (in isoform 2)	Phosphorylation	-	33.01	22210691
470	Ubiquitination	VNLRSRNGWPGAVAH CCCHHCCCCCCCHHH	30.74	23000965
470 (in isoform 2)	Ubiquitination	-	30.74	-
472	Ubiquitination	LRSRNGWPGAVAHAC CHHCCCCCCCHHHCC	23.43	23000965
514	Ubiquitination	WNLSSNDKLKNLMIT EECCCCHHHHHHHHH	66.66	23000965
516	Ubiquitination	LSSNDKLKNLMITEA CCCCHHHHHHHHHHH	54.50	23000965
597	Phosphorylation	VRGTIADYQPDDKAT HHHCCCCCCCCCHHH	16.96	-
599	Ubiquitination	GTIADYQPDDKATEN HCCCCCCCCCHHHCC	45.60	23000965
603	S-palmitoylation	DYQPDDKATENCVCI CCCCCCHHHCCEEEE	27.43	25002405
612	Ubiquitination	ENCVCILHNLSYQLE CCEEEEEECHHHEEE	17.17	29967540
616	Phosphorylation	CILHNLSYQLEAELP EEEECHHHEEEECCC	21.93	-
626	Phosphorylation	EAELPEKYSQNIYIQ EECCCHHHCCCEEEE	17.52	21945579
627	Phosphorylation	AELPEKYSQNIYIQN ECCCHHHCCCEEEEC	28.02	21945579
631	Phosphorylation	EKYSQNIYIQNRNIQ HHHCCCEEEECCCEE	12.19	21945579
643	Ubiquitination	NIQTDNNKSIGCFGS CEECCCCCCCCCCCC	50.10	23000965
650	Phosphorylation	KSIGCFGSRSRKVKE CCCCCCCCCCHHHHH	13.56	24719451
656	Ubiquitination	GSRSRKVKEQYQDVP CCCCHHHHHHHCCCC	41.98	29967540
659	Phosphorylation	SRKVKEQYQDVPMPE CHHHHHHHCCCCCCC	14.05	21945579
686	Phosphorylation	HSIVIRMYLSLIAKS HHHHHHHHHHHHHHH	5.36	20068231
688	Phosphorylation	IVIRMYLSLIAKSVR HHHHHHHHHHHHHHH	10.55	22985185
692	Ubiquitination	MYLSLIAKSVRNYTQ HHHHHHHHHHHHHCH	42.35	29967540
693	Phosphorylation	YLSLIAKSVRNYTQE HHHHHHHHHHHHCHH	19.79	20068231
702	Ubiquitination	RNYTQEASLGALQNL HHHCHHHHHHHHHHC	26.95	29901268
703	Ubiquitination	NYTQEASLGALQNLT HHCHHHHHHHHHHCC	6.32	29967540
736	Ubiquitination	SGLQHTRKMLHVGDP HCCHHHHHEECCCCH	47.14	29967540
744	Phosphorylation	MLHVGDPSVKKTAIS EECCCCHHHHHHHHH	51.84	-
746	Ubiquitination	HVGDPSVKKTAISLL CCCCHHHHHHHHHHH	49.06	29901268
747	Ubiquitination	VGDPSVKKTAISLLR CCCHHHHHHHHHHHH	40.82	29967540
748	Phosphorylation	GDPSVKKTAISLLRN CCHHHHHHHHHHHHH	24.41	29083192
751	Phosphorylation	SVKKTAISLLRNLSR HHHHHHHHHHHHHHH	20.91	29083192
761	Phosphorylation	RNLSRNLSLQNEIAK HHHHHCHHHHHHHHH	31.30	28355574
816	Phosphorylation	NARDLLNTGGIQKIM HHHHHHHCCHHHHEE	36.43	23532336
830	Ubiquitination	MAISAGDAYASNKAS EEEECCHHHHCCHHH	10.81	29967540
831	Phosphorylation	AISAGDAYASNKASK EEECCHHHHCCHHHH	18.46	28985074
833	Phosphorylation	SAGDAYASNKASKAA ECCHHHHCCHHHHHH	26.62	27307780
845	Phosphorylation	KAASVLLYSLWAHTE HHHHHHHHHHHHHHH	9.50	28985074
846	Phosphorylation	AASVLLYSLWAHTEL HHHHHHHHHHHHHHH	19.87	28985074
864	Ubiquitination	YKKAQFKKTDFVNSR HHHHHHCCCCCCCHH	55.40	-
870	Phosphorylation	KKTDFVNSRTAKAYH CCCCCCCHHHHHHHH	26.21	27470641
874	Ubiquitination	FVNSRTAKAYHSLKD CCCHHHHHHHHHCCC	49.19	29967540
876	Phosphorylation	NSRTAKAYHSLKD-- CHHHHHHHHHCCC--	7.40	30266825
878	Phosphorylation	RTAKAYHSLKD---- HHHHHHHHCCC----	25.16	30266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
82	S	Phosphorylation	Kinase	TAK1	O43318	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PKP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PKP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DESP_HUMAN	DSP	physical	11790773
PLAK_HUMAN	JUP	physical	11790773
DSG1_HUMAN	DSG1	physical	11790773
DSG2_HUMAN	DSG2	physical	11790773
DSC1_HUMAN	DSC1	physical	11790773
DSC2_HUMAN	DSC2	physical	11790773
RPC1_HUMAN	POLR3A	physical	11416169
K1C18_HUMAN	KRT18	physical	10852826
K2C5_HUMAN	KRT5	physical	10852826
MARK3_HUMAN	MARK3	physical	12941695
MTUS2_HUMAN	MTUS2	physical	25416956
NDEL1_HUMAN	NDEL1	physical	25416956

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
609040	Arrhythmogenic right ventricular dysplasia, familial, 9 (ARVD9)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PKP2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-151 AND SER-154, ANDMASS SPECTROMETRY.	19369195 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-151 AND SER-155, ANDMASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-151; SER-154; SER-155;SER-197 AND SER-329, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-151; SER-154 ANDSER-155, AND MASS SPECTROMETRY.	18691976 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-132 AND SER-169, ANDMASS SPECTROMETRY.	17525332 [Abstract]
"An extensive survey of tyrosine phosphorylation revealing new sitesin human mammary epithelial cells."; Heibeck T.H., Ding S.-J., Opresko L.K., Zhao R., Schepmoes A.A.,Yang F., Tolmachev A.V., Monroe M.E., Camp D.G. II, Smith R.D.,Wiley H.S., Qian W.-J.; J. Proteome Res. 8:3852-3861(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-12; TYR-86; TYR-161;TYR-166; TYR-168 AND TYR-217, AND MASS SPECTROMETRY.	19534553 [Abstract]
"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer."; Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.; Cell 131:1190-1203(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-168, AND MASSSPECTROMETRY.	18083107 [Abstract]