HECD1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HECD1_HUMAN
• UniProt AC: Q9ULT8
• Protein Name: E3 ubiquitin-protein ligase HECTD1
• Gene Name: HECTD1
• Organism: Homo sapiens (Human).
• Sequence Length: 2610
• Protein Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure..
• Protein Sequence: MADVDPDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLDVSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLSRMAAAGGTVSGPSSACKPGRSTTGAPSTTADSKLSNQVSTIVSLLSTLCRGSPVVTHDLLRSELPDSIESALQGDERCVLDTMRLVDLLLVLLFEGRKALPKSSAGSTGRIPGLRRLDSSGERSHRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRHGANPDLRDEDGKTPLDKARERGHSEVVAILQSPGDWMCPVNKGDDKKKKDTNKDEEECNEPKGDPEMAPIYLKRLLPVFAQTFQQTMLPSIRKASLALIRKMIHFCSEALLKEVCDSDVGHNLPTILVEITATVLDQEDDDDGHLLALQIIRDLVDKGGDIFLDQLARLGVISKVSTLAGPSSDDENEEESKPEKEDEPQEDAKELQQGKPYHWRDWSIIRGRDCLYIWSDAAALELSNGSNGWFRFILDGKLATMYSSGSPEGGSDSSESRSEFLEKLQRARGQVKPSTSSQPILSAPGPTKLTVGNWSLTCLKEGEIAIHNSDGQQATILKEDLPGFVFESNRGTKHSFTAETSLGSEFVTGWTGKRGRKLKSKLEKTKQKVRTMARDLYDDHFKAVESMPRGVVVTLRNIATQLESSWELHTNRQCIESENTWRDLMKTALENLIVLLKDENTISPYEMCSSGLVQALLTVLNNSMDLDMKQDCSQLVERINVFKTAFSENEDDESRPAVALIRKLIAVLESIERLPLHLYDTPGSTYNLQILTRRLRFRLERAPGETALIDRTGRMLKMEPLATVESLEQYLLKMVAKQWYDFDRSSFVFVRKLREGQNFIFRHQHDFDENGIIYWIGTNAKTAYEWVNPAAYGLVVVTSSEGRNLPYGRLEDILSRDNSALNCHSNDDKNAWFAIDLGLWVIPSAYTLRHARGYGRSALRNWVFQVSKDGQNWTSLYTHVDDCSLNEPGSTATWPLDPPKDEKQGWRHVRIKQMGKNASGQTHYLSLSGFELYGTVNGVCEDQLGKAAKEAEANLRRQRRLVRSQVLKYMVPGARVIRGLDWKWRDQDGSPQGEGTVTGELHNGWIDVTWDAGGSNSYRMGAEGKFDLKLAPGYDPDTVASPKPVSSTVSGTTQSWSSLVKNNCPDKTSAAAGSSSRKGSSSSVCSVASSSDISLGSTKTERRSEIVMEHSIVSGADVHEPIVVLSSAENVPQTEVGSSSSASTSTLTAETGSENAERKLGPDSSVRTPGESSAISMGIVSVSSPDVSSVSELTNKEAASQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNATNNMNLSRSSSDNNTNTLGRNVMSTATSPLMGAQSFPNLTTPGTTSTVTMSTSSVTSSSNVATATTVLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAELDDDEDLPEPDEEDDENEDDNQEDQEYEEVMILRRPSLQRRAGSRSDVTHHAVTSQLPQVPAGAGSRPIGEQEEEEYETKGGRRRTWDDDYVLKRQFSALVPAFDPRPGRTNVQQTTDLEIPPPGTPHSELLEEVECTPSPRLALTLKVTGLGTTREVELPLTNFRSTIFYYVQKLLQLSCNGNVKSDKLRRIWEPTYTIMYREMKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKDFCEHGTKSGLNQGAISTLQSSDILNLTKEQPQAKAGNGQNSCGVEDVLQLLRILYIVASDPYSRISQEDGDEQLQFTFPPDEFTSKKITTKILQQIEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDDPGEFRVGRLKHERVKVPRGESLMEWAENVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
56	Ubiquitination	PPRTFLPALCKIFLD CCHHHHHHHHHHHCC	27.95	24816145
100	Ubiquitination	VGVDGAIKALCNRLV HCCHHHHHHHHCCEE	34.47	33845483
114	Methylation	VVVELNNRTSRDLAE EEEECCCCCCHHHHH	32.76	115478425
151	Ubiquitination	LNCVLTFIRDSGHLV CCEEEEEEECCCCEE	3.94	23503661
160	Ubiquitination	DSGHLVHKDTLHSAM CCCCEECHHHHHHHH	44.95	33845483
177	Ubiquitination	VSRLCGKMEPQDSSL HHHHHCCCCCCCCCH	5.72	24816145
182	Phosphorylation	GKMEPQDSSLEICVE CCCCCCCCCHHHHHH	31.41	-
186	Ubiquitination	PQDSSLEICVESLSS CCCCCHHHHHHHHHH	3.75	23503661
193	Phosphorylation	ICVESLSSLLKHEDH HHHHHHHHHHCCCCC	42.91	24719451
202	Ubiquitination	LKHEDHQVSDGALRC HCCCCCCCCHHHHHH	5.16	23503661
216	Methylation	CFASLADRFTRRGVD HHHHHHHHHHHCCCC	29.27	115478417
229	Ubiquitination	VDPAPLAKHGLTEEL CCHHHHHHCCCCHHH	45.98	21906983
233	Phosphorylation	PLAKHGLTEELLSRM HHHHCCCCHHHHHHH	31.82	-
238	Phosphorylation	GLTEELLSRMAAAGG CCCHHHHHHHHHCCC	32.41	24719451
246	Phosphorylation	RMAAAGGTVSGPSSA HHHHCCCCCCCCCCC	15.58	29396449
248	Phosphorylation	AAAGGTVSGPSSACK HHCCCCCCCCCCCCC	44.84	25159151
251	Phosphorylation	GGTVSGPSSACKPGR CCCCCCCCCCCCCCC	33.81	25159151
252	Phosphorylation	GTVSGPSSACKPGRS CCCCCCCCCCCCCCC	40.60	25159151
255	Ubiquitination	SGPSSACKPGRSTTG CCCCCCCCCCCCCCC	50.66	23000965
259	Phosphorylation	SACKPGRSTTGAPST CCCCCCCCCCCCCCC	35.91	-
260	Phosphorylation	ACKPGRSTTGAPSTT CCCCCCCCCCCCCCC	28.08	-
270	Phosphorylation	APSTTADSKLSNQVS CCCCCCCHHHHHHHH	32.79	-
275	Ubiquitination	ADSKLSNQVSTIVSL CCHHHHHHHHHHHHH	27.45	24816145
296	Ubiquitination	GSPVVTHDLLRSELP CCCCCCHHHHHCCCC	37.72	24816145
336	Ubiquitination	VLLFEGRKALPKSSA HHHHCCCCCCCCCCC	66.20	24816145
340	Ubiquitination	EGRKALPKSSAGSTG CCCCCCCCCCCCCCC	58.87	29967540
342	Phosphorylation	RKALPKSSAGSTGRI CCCCCCCCCCCCCCC	42.65	27251275
345	Phosphorylation	LPKSSAGSTGRIPGL CCCCCCCCCCCCCCC	27.66	27251275
346	Phosphorylation	PKSSAGSTGRIPGLR CCCCCCCCCCCCCCC	29.57	27251275
353	Methylation	TGRIPGLRRLDSSGE CCCCCCCCCCCCCCC	42.93	115389333
357	Phosphorylation	PGLRRLDSSGERSHR CCCCCCCCCCCCHHH	44.85	27273156
358	Phosphorylation	GLRRLDSSGERSHRQ CCCCCCCCCCCHHHH	44.32	27273156
362	Phosphorylation	LDSSGERSHRQLIDC CCCCCCCHHHHHHHH	20.79	-
397	Ubiquitination	NFMDDVGQTLLNWAS ECCCHHHHHHHHHHH	28.90	23503661
433	Phosphorylation	QRSSSLHYAACFGRP CCCCCCHHHHHHCCH	10.94	24719451
444	Ubiquitination	FGRPQVAKTLLRHGA HCCHHHHHHHHHCCC	40.63	27667366
445	Phosphorylation	GRPQVAKTLLRHGAN CCHHHHHHHHHCCCC	22.68	24719451
461	Ubiquitination	DLRDEDGKTPLDKAR CCCCCCCCCHHHHHH	60.33	21906983
462	Phosphorylation	LRDEDGKTPLDKARE CCCCCCCCHHHHHHH	34.31	19664994
466	Ubiquitination	DGKTPLDKARERGHS CCCCHHHHHHHCCCC	57.96	21906983
473	Phosphorylation	KARERGHSEVVAILQ HHHHCCCCCCEEEEE	34.60	23532336
481	Phosphorylation	EVVAILQSPGDWMCP CCEEEEECCCCCCCC	27.66	25159151
491	Ubiquitination	DWMCPVNKGDDKKKK CCCCCCCCCCCCCCC	65.04	32015554
511	Acetylation	EEECNEPKGDPEMAP HHHHCCCCCCHHHHH	70.53	26051181
522	Ubiquitination	EMAPIYLKRLLPVFA HHHHHHHHHHHHHHH	24.83	21890473
539	Phosphorylation	FQQTMLPSIRKASLA HHHHCCHHHHHHHHH	30.94	24719451
544	Phosphorylation	LPSIRKASLALIRKM CHHHHHHHHHHHHHH	19.74	21210654
606	Ubiquitination	IIRDLVDKGGDIFLD HHHHHHHCCCCCHHH	58.26	33845483
625	Phosphorylation	LGVISKVSTLAGPSS HCCCEEECCCCCCCC	22.80	23927012
626	Phosphorylation	GVISKVSTLAGPSSD CCCEEECCCCCCCCC	24.50	23927012
631	Phosphorylation	VSTLAGPSSDDENEE ECCCCCCCCCCCCCC	45.54	29255136
632	Phosphorylation	STLAGPSSDDENEEE CCCCCCCCCCCCCCC	52.82	29255136
640	Phosphorylation	DDENEEESKPEKEDE CCCCCCCCCCCCCCC	57.71	22167270
667	Phosphorylation	PYHWRDWSIIRGRDC CCCCCCCHHHCCCCE	16.66	24719451
701	Ubiquitination	FRFILDGKLATMYSS EEEEECCEEEEEECC	34.32	23503661
704	Phosphorylation	ILDGKLATMYSSGSP EECCEEEEEECCCCC	27.38	30576142
706	Phosphorylation	DGKLATMYSSGSPEG CCEEEEEECCCCCCC	8.71	-
707	Phosphorylation	GKLATMYSSGSPEGG CEEEEEECCCCCCCC	19.87	30576142
710	Phosphorylation	ATMYSSGSPEGGSDS EEEECCCCCCCCCCC	23.02	25627689
715	Phosphorylation	SGSPEGGSDSSESRS CCCCCCCCCCHHHHH	45.21	-
717	Phosphorylation	SPEGGSDSSESRSEF CCCCCCCCHHHHHHH	37.39	-
722	Ubiquitination	SDSSESRSEFLEKLQ CCCHHHHHHHHHHHH	41.81	21890473
727	Ubiquitination	SRSEFLEKLQRARGQ HHHHHHHHHHHHCCC	52.66	24816145
736	Ubiquitination	QRARGQVKPSTSSQP HHHCCCCCCCCCCCC	25.93	21906983
737	Ubiquitination	RARGQVKPSTSSQPI HHCCCCCCCCCCCCC	43.94	21890473
752	Ubiquitination	LSAPGPTKLTVGNWS CCCCCCCEEEECCEE	45.34	23503661
754	Phosphorylation	APGPTKLTVGNWSLT CCCCCEEEECCEEEE	28.11	21406692
759	Phosphorylation	KLTVGNWSLTCLKEG EEEECCEEEEEEEEC	20.14	21406692
761	Phosphorylation	TVGNWSLTCLKEGEI EECCEEEEEEEECEE	15.41	21406692
782	Ubiquitination	GQQATILKEDLPGFV CCEEEEEECCCCCEE	45.38	29967540
804	Phosphorylation	KHSFTAETSLGSEFV CCEEEEEEECCCCCC	27.13	24275569
815	Phosphorylation	SEFVTGWTGKRGRKL CCCCCCCCCHHHHHH	33.88	22210691
821	Ubiquitination	WTGKRGRKLKSKLEK CCCHHHHHHHHHHHH	64.19	27667366
825	Acetylation	RGRKLKSKLEKTKQK HHHHHHHHHHHHHHH	60.11	7851419
825	Ubiquitination	RGRKLKSKLEKTKQK HHHHHHHHHHHHHHH	60.11	24816145
828	Acetylation	KLKSKLEKTKQKVRT HHHHHHHHHHHHHHH	72.03	7851429
846	Ubiquitination	DLYDDHFKAVESMPR HHCHHHHHHHHCCCC	48.37	24816145
858	Phosphorylation	MPRGVVVTLRNIATQ CCCCEEEEEHHHHHH	14.37	-
891	O-linked_Glycosylation	TWRDLMKTALENLIV HHHHHHHHHHHHHHH	23.62	30059200
913	Ubiquitination	ISPYEMCSSGLVQAL CCHHHHCHHHHHHHH	26.57	27667366
947	Ubiquitination	VERINVFKTAFSENE HHHHHHHHHHCCCCC	34.36	21906983
950	Ubiquitination	INVFKTAFSENEDDE HHHHHHHCCCCCCCC	13.09	21963094
1027	Phosphorylation	LKMEPLATVESLEQY CCCEECCCHHHHHHH	32.27	23836654
1030	Phosphorylation	EPLATVESLEQYLLK EECCCHHHHHHHHHH	32.63	29978859
1034	Phosphorylation	TVESLEQYLLKMVAK CHHHHHHHHHHHHHH	12.48	29978859
1041	Ubiquitination	YLLKMVAKQWYDFDR HHHHHHHHHHHCCCC	29.92	-
1044	Phosphorylation	KMVAKQWYDFDRSSF HHHHHHHHCCCCHHE	12.30	-
1088	Phosphorylation	GTNAKTAYEWVNPAA ECCCCHHHHCCCHHH	18.63	24248375
1102	Phosphorylation	AYGLVVVTSSEGRNL HCEEEEEECCCCCCC	18.22	24248375
1103	Phosphorylation	YGLVVVTSSEGRNLP CEEEEEECCCCCCCC	18.12	24248375
1104	Phosphorylation	GLVVVTSSEGRNLPY EEEEEECCCCCCCCC	34.40	24248375
1111	Phosphorylation	SEGRNLPYGRLEDIL CCCCCCCCCCHHHHH	20.31	20068231
1119	Phosphorylation	GRLEDILSRDNSALN CCHHHHHCCCCCCCC	37.61	20068231
1151	Phosphorylation	WVIPSAYTLRHARGY EEECCHHHHHHCCCC	19.62	24719451
1204	Ubiquitination	TWPLDPPKDEKQGWR CCCCCCCCCCCCCCE	81.53	21963094
1218	Ubiquitination	RHVRIKQMGKNASGQ EEEEEEEECCCCCCC	7.58	21890473
1253	Ubiquitination	DQLGKAAKEAEANLR HHHHHHHHHHHHHHH	63.42	29967540
1272	Ubiquitination	LVRSQVLKYMVPGAR HHHHHHHHHHCCCCE	32.23	23000965
1273	Phosphorylation	VRSQVLKYMVPGARV HHHHHHHHHCCCCEE	10.13	-
1274	Ubiquitination	RSQVLKYMVPGARVI HHHHHHHHCCCCEEE	2.54	21890473
1287	Ubiquitination	VIRGLDWKWRDQDGS EECCCCCEEECCCCC	31.83	21890473
1289	Ubiquitination	RGLDWKWRDQDGSPQ CCCCCEEECCCCCCC	28.17	21890473
1324	Ubiquitination	GGSNSYRMGAEGKFD CCCCCCCCCCCCCCE	4.53	27667366
1338	Phosphorylation	DLKLAPGYDPDTVAS EEEECCCCCCCCCCC	24.20	28450419
1342	O-linked_Glycosylation	APGYDPDTVASPKPV CCCCCCCCCCCCCCC	24.30	30059200
1342	Phosphorylation	APGYDPDTVASPKPV CCCCCCCCCCCCCCC	24.30	28450419
1345	O-linked_Glycosylation	YDPDTVASPKPVSST CCCCCCCCCCCCCCC	29.17	30059200
1345	Phosphorylation	YDPDTVASPKPVSST CCCCCCCCCCCCCCC	29.17	25159151
1347	Phosphorylation	PDTVASPKPVSSTVS CCCCCCCCCCCCCCC	56.40	18669648
1350	O-linked_Glycosylation	VASPKPVSSTVSGTT CCCCCCCCCCCCCCC	28.90	30059200
1350	Phosphorylation	VASPKPVSSTVSGTT CCCCCCCCCCCCCCC	28.90	28450419
1351	O-linked_Glycosylation	ASPKPVSSTVSGTTQ CCCCCCCCCCCCCCC	32.82	30059200
1351	Phosphorylation	ASPKPVSSTVSGTTQ CCCCCCCCCCCCCCC	32.82	28450419
1352	Phosphorylation	SPKPVSSTVSGTTQS CCCCCCCCCCCCCCC	15.93	28450419
1354	Phosphorylation	KPVSSTVSGTTQSWS CCCCCCCCCCCCCHH	30.43	28450419
1356	Phosphorylation	VSSTVSGTTQSWSSL CCCCCCCCCCCHHHH	17.73	28450419
1357	Phosphorylation	SSTVSGTTQSWSSLV CCCCCCCCCCHHHHH	24.91	28450419
1359	Phosphorylation	TVSGTTQSWSSLVKN CCCCCCCCHHHHHHC	27.17	26074081
1361	Phosphorylation	SGTTQSWSSLVKNNC CCCCCCHHHHHHCCC	21.02	27732954
1362	Phosphorylation	GTTQSWSSLVKNNCP CCCCCHHHHHHCCCC	30.81	27732954
1369	Ubiquitination	SLVKNNCPDKTSAAA HHHHCCCCCCCCCCC	48.53	21890473
1371	Ubiquitination	VKNNCPDKTSAAAGS HHCCCCCCCCCCCCC	29.53	33845483
1372	O-linked_Glycosylation	KNNCPDKTSAAAGSS HCCCCCCCCCCCCCC	30.86	30059200
1372	Phosphorylation	KNNCPDKTSAAAGSS HCCCCCCCCCCCCCC	30.86	28634120
1373	O-linked_Glycosylation	NNCPDKTSAAAGSSS CCCCCCCCCCCCCCC	22.96	30059200
1373	Phosphorylation	NNCPDKTSAAAGSSS CCCCCCCCCCCCCCC	22.96	26434776
1378	Phosphorylation	KTSAAAGSSSRKGSS CCCCCCCCCCCCCCC	22.03	26329039
1379	Phosphorylation	TSAAAGSSSRKGSSS CCCCCCCCCCCCCCC	32.99	28985074
1380	Phosphorylation	SAAAGSSSRKGSSSS CCCCCCCCCCCCCCC	39.44	30576142
1382	Ubiquitination	AAGSSSRKGSSSSVC CCCCCCCCCCCCCCC	66.16	33845483
1384	Phosphorylation	GSSSRKGSSSSVCSV CCCCCCCCCCCCCCH	30.04	30278072
1385	Phosphorylation	SSSRKGSSSSVCSVA CCCCCCCCCCCCCHH	34.99	30278072
1386	Phosphorylation	SSRKGSSSSVCSVAS CCCCCCCCCCCCHHC	28.61	30278072
1386	Ubiquitination	SSRKGSSSSVCSVAS CCCCCCCCCCCCHHC	28.61	27667366
1387	Phosphorylation	SRKGSSSSVCSVASS CCCCCCCCCCCHHCC	29.14	30278072
1390	Phosphorylation	GSSSSVCSVASSSDI CCCCCCCCHHCCCCC	20.68	23927012
1393	Phosphorylation	SSVCSVASSSDISLG CCCCCHHCCCCCCCC	28.37	23927012
1394	Phosphorylation	SVCSVASSSDISLGS CCCCHHCCCCCCCCC	23.46	23927012
1395	Phosphorylation	VCSVASSSDISLGST CCCHHCCCCCCCCCC	36.15	28450419
1398	Phosphorylation	VASSSDISLGSTKTE HHCCCCCCCCCCCCC	31.50	23927012
1401	Phosphorylation	SSDISLGSTKTERRS CCCCCCCCCCCCCHH	31.83	23927012
1416	Ubiquitination	EIVMEHSIVSGADVH HHHHHCEECCCCCCC	2.85	27667366
1431	Ubiquitination	EPIVVLSSAENVPQT CCEEEEECCCCCCCC	35.13	23503661
1437	Ubiquitination	SSAENVPQTEVGSSS ECCCCCCCCCCCCCC	46.11	23503661
1453	Ubiquitination	ASTSTLTAETGSENA CCCCEEEECCCCCCH	18.57	21963094
1463	Ubiquitination	GSENAERKLGPDSSV CCCCHHHHCCCCCCC	49.66	27667366
1468	Phosphorylation	ERKLGPDSSVRTPGE HHHCCCCCCCCCCCC	33.59	22199227
1469	Phosphorylation	RKLGPDSSVRTPGES HHCCCCCCCCCCCCC	24.01	30576142
1471	Phosphorylation	LGPDSSVRTPGESSA CCCCCCCCCCCCCCC	36.83	18669648
1472	Phosphorylation	GPDSSVRTPGESSAI CCCCCCCCCCCCCCE	33.23	22199227
1473	Ubiquitination	PDSSVRTPGESSAIS CCCCCCCCCCCCCEE	33.71	21963094
1474	Phosphorylation	DSSVRTPGESSAISM CCCCCCCCCCCCEEE	46.97	18669648
1475	Ubiquitination	SSVRTPGESSAISMG CCCCCCCCCCCEEEE	42.60	21963094
1476	Phosphorylation	SVRTPGESSAISMGI CCCCCCCCCCEEEEE	30.87	30576142
1477	Phosphorylation	VRTPGESSAISMGIV CCCCCCCCCEEEEEE	25.89	30576142
1479	Phosphorylation	TPGESSAISMGIVSV CCCCCCCEEEEEEEE	2.92	18669648
1485	Phosphorylation	AISMGIVSVSSPDVS CEEEEEEEECCCCCH	17.86	22199227
1487	Phosphorylation	SMGIVSVSSPDVSSV EEEEEEECCCCCHHH	28.75	30278072
1487	Ubiquitination	SMGIVSVSSPDVSSV EEEEEEECCCCCHHH	28.75	21890473
1488	Phosphorylation	MGIVSVSSPDVSSVS EEEEEECCCCCHHHH	23.98	30278072
1489	Phosphorylation	GIVSVSSPDVSSVSE EEEEECCCCCHHHHH	38.22	18669648
1489	Ubiquitination	GIVSVSSPDVSSVSE EEEEECCCCCHHHHH	38.22	21890473
1490	Phosphorylation	IVSVSSPDVSSVSEL EEEECCCCCHHHHHH	55.68	18669648
1492	Phosphorylation	SVSSPDVSSVSELTN EECCCCCHHHHHHCC	32.19	25841592
1493	Phosphorylation	VSSPDVSSVSELTNK ECCCCCHHHHHHCCH	29.52	22199227
1495	Phosphorylation	SPDVSSVSELTNKEA CCCCHHHHHHCCHHH	28.92	22199227
1498	Phosphorylation	VSSVSELTNKEAASQ CHHHHHHCCHHHHHC	39.95	22199227
1500	Ubiquitination	SVSELTNKEAASQRP HHHHHCCHHHHHCCC	43.42	21906983
1502	Ubiquitination	SELTNKEAASQRPLS HHHCCHHHHHCCCCC	17.64	21890473
1504	Phosphorylation	LTNKEAASQRPLSSS HCCHHHHHCCCCCCH	33.50	21406692
1509	O-linked_Glycosylation	AASQRPLSSSASNRL HHHCCCCCCHHHCCC	25.57	30059200
1509	Phosphorylation	AASQRPLSSSASNRL HHHCCCCCCHHHCCC	25.57	27050516
1510	O-linked_Glycosylation	ASQRPLSSSASNRLS HHCCCCCCHHHCCCC	37.29	30059200
1510	Phosphorylation	ASQRPLSSSASNRLS HHCCCCCCHHHCCCC	37.29	21406692
1511	Phosphorylation	SQRPLSSSASNRLSV HCCCCCCHHHCCCCH	32.13	30576142
1513	Phosphorylation	RPLSSSASNRLSVSS CCCCCHHHCCCCHHH	25.16	25159151
1517	Phosphorylation	SSASNRLSVSSLLAA CHHHCCCCHHHHHHC	19.40	27050516
1519	Phosphorylation	ASNRLSVSSLLAAGA HHCCCCHHHHHHCCC	16.34	27732954
1520	Phosphorylation	SNRLSVSSLLAAGAP HCCCCHHHHHHCCCC	25.83	27732954
1529	Phosphorylation	LAAGAPMSSSASVPN HHCCCCCCCCCCCCC	21.78	22199227
1530	O-linked_Glycosylation	AAGAPMSSSASVPNL HCCCCCCCCCCCCCC	24.54	30059200
1530	Phosphorylation	AAGAPMSSSASVPNL HCCCCCCCCCCCCCC	24.54	25850435
1531	O-linked_Glycosylation	AGAPMSSSASVPNLS CCCCCCCCCCCCCCC	19.77	30059200
1531	Phosphorylation	AGAPMSSSASVPNLS CCCCCCCCCCCCCCC	19.77	25850435
1533	Phosphorylation	APMSSSASVPNLSSR CCCCCCCCCCCCCCC	39.80	30183078
1538	Phosphorylation	SASVPNLSSRETSSL CCCCCCCCCCCCHHH	33.71	22199227
1539	Phosphorylation	ASVPNLSSRETSSLE CCCCCCCCCCCHHHH	36.98	22199227
1542	Phosphorylation	PNLSSRETSSLESFV CCCCCCCCHHHHHHH	23.62	29255136
1543	Phosphorylation	NLSSRETSSLESFVR CCCCCCCHHHHHHHH	28.33	29255136
1544	Phosphorylation	LSSRETSSLESFVRR CCCCCCHHHHHHHHH	43.50	29255136
1547	Phosphorylation	RETSSLESFVRRVAN CCCHHHHHHHHHHHH	34.04	29255136
1558	Phosphorylation	RVANIARTNATNNMN HHHHHHHCCCCCCCC	21.86	28450419
1561	Phosphorylation	NIARTNATNNMNLSR HHHHCCCCCCCCCCC	29.24	28450419
1567	Phosphorylation	ATNNMNLSRSSSDNN CCCCCCCCCCCCCCC	25.72	19664994
1569	O-linked_Glycosylation	NNMNLSRSSSDNNTN CCCCCCCCCCCCCCC	30.71	30059200
1569	Phosphorylation	NNMNLSRSSSDNNTN CCCCCCCCCCCCCCC	30.71	30278072
1570	O-linked_Glycosylation	NMNLSRSSSDNNTNT CCCCCCCCCCCCCCC	40.37	30059200
1570	Phosphorylation	NMNLSRSSSDNNTNT CCCCCCCCCCCCCCC	40.37	30278072
1571	O-linked_Glycosylation	MNLSRSSSDNNTNTL CCCCCCCCCCCCCCC	45.67	30059200
1571	Phosphorylation	MNLSRSSSDNNTNTL CCCCCCCCCCCCCCC	45.67	30278072
1575	Phosphorylation	RSSSDNNTNTLGRNV CCCCCCCCCCCCHHH	35.52	28450419
1577	Phosphorylation	SSDNNTNTLGRNVMS CCCCCCCCCCHHHHH	28.66	28450419
1638	Ubiquitination	GQSLSNTLTTSLTST HHHHHHHHCEEEECC	6.02	21890473
1640	Ubiquitination	SLSNTLTTSLTSTSS HHHHHHCEEEECCCC	25.50	21890473
1655	Ubiquitination	ESDTGQEAEYSLYDF CCCCCCEEEEHHHHH	17.09	27667366
1657	Phosphorylation	DTGQEAEYSLYDFLD CCCCEEEEHHHHHHH	15.83	-
1657	Ubiquitination	DTGQEAEYSLYDFLD CCCCEEEEHHHHHHH	15.83	27667366
1660	Phosphorylation	QEAEYSLYDFLDSCR CEEEEHHHHHHHHCC	9.94	25884760
1700	Ubiquitination	DDNQEDQEYEEVMIL CCCHHHHHHHHHHEE	68.20	23503661
1701	Phosphorylation	DNQEDQEYEEVMILR CCHHHHHHHHHHEEE	16.26	27642862
1702	Ubiquitination	NQEDQEYEEVMILRR CHHHHHHHHHHEEEC	43.28	23503661
1705	Ubiquitination	DQEYEEVMILRRPSL HHHHHHHHEEECHHH	2.43	21963094
1706	Ubiquitination	QEYEEVMILRRPSLQ HHHHHHHEEECHHHH	3.06	23503661
1707	Ubiquitination	EYEEVMILRRPSLQR HHHHHHEEECHHHHH	1.73	21963094
1708	Ubiquitination	YEEVMILRRPSLQRR HHHHHEEECHHHHHH	37.22	23503661
1711	Phosphorylation	VMILRRPSLQRRAGS HHEEECHHHHHHCCC	35.01	26846344
1718	Phosphorylation	SLQRRAGSRSDVTHH HHHHHCCCCCCCCHH	27.85	29978859
1718	Ubiquitination	SLQRRAGSRSDVTHH HHHHHCCCCCCCCHH	27.85	21890473
1719	Ubiquitination	LQRRAGSRSDVTHHA HHHHCCCCCCCCHHH	35.64	21890473
1720	Phosphorylation	QRRAGSRSDVTHHAV HHHCCCCCCCCHHHH	37.82	29978859
1721	Ubiquitination	RRAGSRSDVTHHAVT HHCCCCCCCCHHHHH	48.50	21890473
1722	Ubiquitination	RAGSRSDVTHHAVTS HCCCCCCCCHHHHHC	6.06	23000965
1723	Phosphorylation	AGSRSDVTHHAVTSQ CCCCCCCCHHHHHCC	16.97	29978859
1728	Phosphorylation	DVTHHAVTSQLPQVP CCCHHHHHCCCCCCC	16.13	29978859
1729	Phosphorylation	VTHHAVTSQLPQVPA CCHHHHHCCCCCCCC	24.11	29978859
1740	Phosphorylation	QVPAGAGSRPIGEQE CCCCCCCCCCCCCCC	34.06	21406692
1751	Phosphorylation	GEQEEEEYETKGGRR CCCCHHHCCCCCCCC	31.98	29978859
1752	Ubiquitination	EQEEEEYETKGGRRR CCCHHHCCCCCCCCC	47.53	21963094
1753	Phosphorylation	QEEEEYETKGGRRRT CCHHHCCCCCCCCCC	33.80	21406692
1754	Ubiquitination	EEEEYETKGGRRRTW CHHHCCCCCCCCCCC	47.64	21906983
1756	Ubiquitination	EEYETKGGRRRTWDD HHCCCCCCCCCCCCH	22.83	21890473
1760	Phosphorylation	TKGGRRRTWDDDYVL CCCCCCCCCCHHHHH	31.28	27273156
1765	Phosphorylation	RRTWDDDYVLKRQFS CCCCCHHHHHHHHHH	18.06	23312004
1766	Ubiquitination	RTWDDDYVLKRQFSA CCCCHHHHHHHHHHH	6.99	21890473
1768	Ubiquitination	WDDDYVLKRQFSALV CCHHHHHHHHHHHHC	33.82	33845483
1770	Ubiquitination	DDYVLKRQFSALVPA HHHHHHHHHHHHCCC	34.75	21890473
1772	Phosphorylation	YVLKRQFSALVPAFD HHHHHHHHHHCCCCC	16.62	29255136
1774	Phosphorylation	LKRQFSALVPAFDPR HHHHHHHHCCCCCCC	4.61	18669648
1785	Phosphorylation	FDPRPGRTNVQQTTD CCCCCCCCCCCEECC	45.73	28122231
1790	Phosphorylation	GRTNVQQTTDLEIPP CCCCCCEECCCCCCC	12.75	28122231
1791	Phosphorylation	RTNVQQTTDLEIPPP CCCCCEECCCCCCCC	33.96	28122231
1800	Phosphorylation	LEIPPPGTPHSELLE CCCCCCCCCCHHHHH	24.49	29978859
1803	Phosphorylation	PPPGTPHSELLEEVE CCCCCCCHHHHHHCC	31.01	29978859
1814	Ubiquitination	EEVECTPSPRLALTL HHCCCCCCCCEEEEE	12.42	21890473
1849	Ubiquitination	TIFYYVQKLLQLSCN HHHHHHHHHHHHHCC	40.91	-
1860	Ubiquitination	LSCNGNVKSDKLRRI HHCCCCCCCHHHHHH	57.86	33845483
1870	Ubiquitination	KLRRIWEPTYTIMYR HHHHHHCCEEEEEEE	18.73	21890473
1872	Ubiquitination	RRIWEPTYTIMYREM HHHHCCEEEEEEECC	12.65	21890473
1876	Phosphorylation	EPTYTIMYREMKDSD CCEEEEEEECCCCCH	10.28	-
1887	Ubiquitination	KDSDKEKENGKMGCW CCCHHHHHCCCCCCE	72.76	27667366
1889	Ubiquitination	SDKEKENGKMGCWSI CHHHHHCCCCCCEEH	23.55	27667366
1910	Acetylation	LGTDELPKNDLITYL HCCCCCCHHHHHHHH	75.59	26051181
1917	Ubiquitination	KNDLITYLQKNADAA HHHHHHHHHHCCCHH	4.35	21890473
1919	Ubiquitination	DLITYLQKNADAAFL HHHHHHHHCCCHHHH	52.05	21890473
1920	Ubiquitination	LITYLQKNADAAFLR HHHHHHHCCCHHHHH	30.05	23503661
1921	Ubiquitination	ITYLQKNADAAFLRH HHHHHHCCCHHHHHH	18.17	21890473
1926	Ubiquitination	KNADAAFLRHWKLTG HCCCHHHHHHHHCCC	3.18	23503661
1927	Ubiquitination	NADAAFLRHWKLTGT CCCHHHHHHHHCCCC	27.45	23000965
1930	Ubiquitination	AAFLRHWKLTGTNKS HHHHHHHHCCCCCHH	30.00	29967540
1932	O-linked_Glycosylation	FLRHWKLTGTNKSIR HHHHHHCCCCCHHHH	37.93	30059200
1932	Ubiquitination	FLRHWKLTGTNKSIR HHHHHHCCCCCHHHH	37.93	23503661
1934	Phosphorylation	RHWKLTGTNKSIRKN HHHHCCCCCHHHHCC	33.95	26434776
1934	Ubiquitination	RHWKLTGTNKSIRKN HHHHCCCCCHHHHCC	33.95	27667366
1936	Ubiquitination	WKLTGTNKSIRKNRN HHCCCCCHHHHCCCC	47.28	27667366
1937	Phosphorylation	KLTGTNKSIRKNRNC HCCCCCHHHHCCCCH	29.69	24719451
1938	Ubiquitination	LTGTNKSIRKNRNCS CCCCCHHHHCCCCHH	8.52	23503661
1940	Ubiquitination	GTNKSIRKNRNCSQL CCCHHHHCCCCHHHH	59.60	23503661
1945	Phosphorylation	IRKNRNCSQLIAAYK HHCCCCHHHHHHHHH	31.41	25159151
1960	Ubiquitination	DFCEHGTKSGLNQGA HHHHHCCCCCCCCCH	47.31	29967540
1979	Ubiquitination	QSSDILNLTKEQPQA HHHHHHCCCCCCCCH	6.93	23503661
1980	Phosphorylation	SSDILNLTKEQPQAK HHHHHCCCCCCCCHH	31.31	21712546
1981	Ubiquitination	SDILNLTKEQPQAKA HHHHCCCCCCCCHHC	58.48	21906983
1983	Ubiquitination	ILNLTKEQPQAKAGN HHCCCCCCCCHHCCC	36.64	21890473
1985	Ubiquitination	NLTKEQPQAKAGNGQ CCCCCCCCHHCCCCC	56.01	23503661
1987	Ubiquitination	TKEQPQAKAGNGQNS CCCCCCHHCCCCCCC	52.13	21890473
1989	Ubiquitination	EQPQAKAGNGQNSCG CCCCHHCCCCCCCCC	37.79	21890473
1991	Ubiquitination	PQAKAGNGQNSCGVE CCHHCCCCCCCCCHH	27.42	23000965
1993	Ubiquitination	AKAGNGQNSCGVEDV HHCCCCCCCCCHHHH	40.44	23000965
2034	Ubiquitination	LQFTFPPDEFTSKKI CEEECCCHHHCCCHH	64.97	21963094
2055	Ubiquitination	QIEEPLALASGALPD HCHHHHHHHCCCCHH	5.26	21890473
2070	Ubiquitination	WCEQLTSKCPFLIPF HHHHHHHCCCEEEEC	40.46	-
2083	Ubiquitination	PFETRQLYFTCTAFG ECCCCHHEEHHHHHC	6.63	21890473
2085	Ubiquitination	ETRQLYFTCTAFGAS CCCHHEEHHHHHCCH	8.73	21890473
2112	Phosphorylation	TVERTRTTSSVRRDD EEEEEECCCCCCCCC	18.73	27251275
2113	Phosphorylation	VERTRTTSSVRRDDP EEEEECCCCCCCCCC	26.65	27251275
2114	O-linked_Glycosylation	ERTRTTSSVRRDDPG EEEECCCCCCCCCCC	19.97	30059200
2114	Phosphorylation	ERTRTTSSVRRDDPG EEEECCCCCCCCCCC	19.97	28555341
2190	Ubiquitination	AEFQRTDLGAWLCDD HHHCCCCCCCCCCCC	5.08	21890473
2192	Ubiquitination	FQRTDLGAWLCDDNF HCCCCCCCCCCCCCC	11.90	21890473
2196	Ubiquitination	DLGAWLCDDNFPDDE CCCCCCCCCCCCCCC	52.28	23000965
2198	Ubiquitination	GAWLCDDNFPDDESR CCCCCCCCCCCCCCC	36.78	23000965
2207	Ubiquitination	PDDESRHVDLGGGLK CCCCCCCEECCCCCC	6.72	21890473
2211	Ubiquitination	SRHVDLGGGLKPPGY CCCEECCCCCCCCCE	45.62	23000965
2214	Ubiquitination	VDLGGGLKPPGYYVQ EECCCCCCCCCEEEE	53.06	-
2219	Ubiquitination	GLKPPGYYVQRSCGL CCCCCCEEEECCCCC	8.95	21890473
2221	Ubiquitination	KPPGYYVQRSCGLFT CCCCEEEECCCCCEE	18.56	21890473
2223	Ubiquitination	PGYYVQRSCGLFTAP CCEEEECCCCCEECC	8.75	23000965
2225	Ubiquitination	YYVQRSCGLFTAPFP EEEECCCCCEECCCC	25.68	23000965
2266	Ubiquitination	NRLVDLPISKPFFKL CCCCCCCCCCHHHHH	12.28	21890473
2268	Ubiquitination	LVDLPISKPFFKLMC CCCCCCCCHHHHHHH	46.71	23000965
2270	Ubiquitination	DLPISKPFFKLMCMG CCCCCCHHHHHHHHH	10.95	21890473
2272	Ubiquitination	PISKPFFKLMCMGDI CCCCHHHHHHHHHHH	35.37	23000965
2280	Ubiquitination	LMCMGDIKSNMSKLI HHHHHHHHHHHHHHH	40.28	29967540
2285	Ubiquitination	DIKSNMSKLIYESRG HHHHHHHHHHHHCCC	28.30	33845483
2288	Phosphorylation	SNMSKLIYESRGDRD HHHHHHHHHCCCCCC	20.49	30257219
2303	Phosphorylation	LHCTESQSEASTEEG CCCCCCCCCCCCCCC	44.39	30576142
2303	Ubiquitination	LHCTESQSEASTEEG CCCCCCCCCCCCCCC	44.39	21890473
2305	Ubiquitination	CTESQSEASTEEGHD CCCCCCCCCCCCCCC	27.31	21963094
2306	Phosphorylation	TESQSEASTEEGHDS CCCCCCCCCCCCCCC	32.09	30576142
2307	Phosphorylation	ESQSEASTEEGHDSL CCCCCCCCCCCCCCC	45.14	30576142
2313	Phosphorylation	STEEGHDSLSVGSFE CCCCCCCCCCCCCCC	19.50	30576142
2315	Phosphorylation	EEGHDSLSVGSFEED CCCCCCCCCCCCCCC	28.52	30576142
2315	Ubiquitination	EEGHDSLSVGSFEED CCCCCCCCCCCCCCC	28.52	21890473
2317	Ubiquitination	GHDSLSVGSFEEDSK CCCCCCCCCCCCCCC	24.20	21890473
2318	Phosphorylation	HDSLSVGSFEEDSKS CCCCCCCCCCCCCCC	27.59	30576142
2323	Phosphorylation	VGSFEEDSKSEFILD CCCCCCCCCCCCCCC	41.16	26471730
2324	Ubiquitination	GSFEEDSKSEFILDP CCCCCCCCCCCCCCC	67.34	21890473
2326	Ubiquitination	FEEDSKSEFILDPPK CCCCCCCCCCCCCCC	40.21	21890473
2362	Ubiquitination	HRARFLKEIKDLAIK HHHHHHHHHHHHHHH	58.37	21890473
2364	Ubiquitination	ARFLKEIKDLAIKRR HHHHHHHHHHHHHHH	48.02	33845483
2366	Ubiquitination	FLKEIKDLAIKRRQI HHHHHHHHHHHHHHH	4.51	21890473
2375	Phosphorylation	IKRRQILSNKGLSED HHHHHHHHCCCCCHH	37.82	-
2377	Ubiquitination	RRQILSNKGLSEDEK HHHHHHCCCCCHHHH	58.83	32015554
2380	Phosphorylation	ILSNKGLSEDEKNTK HHHCCCCCHHHHHHH	52.23	30622161
2386	Phosphorylation	LSEDEKNTKLQELVL CCHHHHHHHHHHHHH	44.17	30622161
2387	Ubiquitination	SEDEKNTKLQELVLK CHHHHHHHHHHHHHH	58.53	29967540
2410	Ubiquitination	LSIEDLGLNFQFCPS CCHHHHCCCEEECCC	8.25	21890473
2416	Ubiquitination	GLNFQFCPSSRIYGF CCCEEECCCCCEECE	36.31	23000965
2422	Ubiquitination	CPSSRIYGFTAVDLK CCCCCEECEEEEECC	15.85	21890473
2424	Ubiquitination	SSRIYGFTAVDLKPS CCCEECEEEEECCCC	22.78	21890473
2428	Ubiquitination	YGFTAVDLKPSGEDE ECEEEEECCCCCCCC	7.65	23000965
2430	Ubiquitination	FTAVDLKPSGEDEMI EEEEECCCCCCCCCE	55.66	23000965
2460	Ubiquitination	CMHTGIQKQMEAFRD HHHHCHHHHHHHHHH	50.09	-
2469	Ubiquitination	MEAFRDGFNKVFPME HHHHHHCCCCCCCHH	10.55	21890473
2471	Ubiquitination	AFRDGFNKVFPMEKL HHHHCCCCCCCHHHH	42.88	23000965
2473	Ubiquitination	RDGFNKVFPMEKLSS HHCCCCCCCHHHHCC	5.21	21890473
2475	Ubiquitination	GFNKVFPMEKLSSFS CCCCCCCHHHHCCCC	4.88	23000965
2477	Ubiquitination	NKVFPMEKLSSFSHE CCCCCHHHHCCCCHH	47.63	23000965
2513	Phosphorylation	YTEPKLGYTRDSPGF CCCCCCCCCCCCCCH	14.72	26270265
2514	Phosphorylation	TEPKLGYTRDSPGFL CCCCCCCCCCCCCHH	26.63	26270265
2517	Phosphorylation	KLGYTRDSPGFLRFV CCCCCCCCCCHHHHH	24.51	26270265
2523	Ubiquitination	DSPGFLRFVRVLCGM CCCCHHHHHHHHHCC	4.47	21963094
2535	Ubiquitination	CGMSSDERKAFLQFT HCCCHHHHHHHHHHH	40.36	21963094
2537	Ubiquitination	MSSDERKAFLQFTTG CCHHHHHHHHHHHCC	19.32	21963094
2544	Ubiquitination	AFLQFTTGCSTLPPG HHHHHHCCCCCCCCC	10.58	21890473
2556	Ubiquitination	PPGGLANLHPRLTVV CCCCCCCCCCCEEEE	4.97	21890473
2558	Ubiquitination	GGLANLHPRLTVVRK CCCCCCCCCEEEEEE	35.82	21890473
2582	Ubiquitination	SVNTCVHYLKLPEYS CCCCCEEECCCCCCC	5.78	21963094
2584	Acetylation	NTCVHYLKLPEYSSE CCCEEECCCCCCCCH	55.63	26051181
2584	Ubiquitination	NTCVHYLKLPEYSSE CCCEEECCCCCCCCH	55.63	21963094
2603	Ubiquitination	ERLLAATMEKGFHLN HHHHHHHHHHCCCCC	4.26	21890473
2605	Ubiquitination	LLAATMEKGFHLN-- HHHHHHHHCCCCC--	56.93	23000965
2607	Ubiquitination	AATMEKGFHLN---- HHHHHHCCCCC----	9.80	21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HECD1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HECD1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HECD1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BT3L4_HUMAN	BTF3L4	physical	22863883
2A5D_HUMAN	PPP2R5D	physical	22863883
PRDX1_HUMAN	PRDX1	physical	22863883
ZRAN1_HUMAN	ZRANB1	physical	23277359
HECD1_HUMAN	HECTD1	physical	26949039
UB2D3_HUMAN	UBE2D3	physical	26949039
HECD1_HUMAN	HECTD1	physical	28425671

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-632, AND MASSSPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1488 AND SER-1772, ANDMASS SPECTROMETRY.
PubMed: 18669648