BT3L4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BT3L4_HUMAN
• UniProt AC: Q96K17
• Protein Name: Transcription factor BTF3 homolog 4
• Gene Name: BTF3L4
• Organism: Homo sapiens (Human).
• Sequence Length: 158
• Protein Sequence: MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Ubiquitination	---MNQEKLAKLQAQ ---CCHHHHHHHHHH	43.94	23000965
5	Methylation	---MNQEKLAKLQAQ ---CCHHHHHHHHHH	43.94	-
8	Ubiquitination	MNQEKLAKLQAQVRI CCHHHHHHHHHHHCC	52.12	23000965
18	Methylation	AQVRIGGKGTARRKK HHHCCCCCCCHHHCC	48.12	-
18	Ubiquitination	AQVRIGGKGTARRKK HHHCCCCCCCHHHCC	48.12	22053931
18	Acetylation	AQVRIGGKGTARRKK HHHCCCCCCCHHHCC	48.12	7708529
20	Phosphorylation	VRIGGKGTARRKKKV HCCCCCCCHHHCCCE	22.07	22496350
26	Ubiquitination	GTARRKKKVVHRTAT CCHHHCCCEEEECCC	53.15	24816145
31	Phosphorylation	KKKVVHRTATADDKK CCCEEEECCCCCHHH	17.30	22496350
33	Phosphorylation	KVVHRTATADDKKLQ CEEEECCCCCHHHHH	29.97	26657352
37	Ubiquitination	RTATADDKKLQSSLK ECCCCCHHHHHHHHH	56.80	-
38	Ubiquitination	TATADDKKLQSSLKK CCCCCHHHHHHHHHH	59.77	29967540
57	Ubiquitination	NIAGIEEVNMIKDDG HCCCCEEEEEECCCC	3.70	22817900
70	Ubiquitination	DGTVIHFNNPKVQAS CCEEEEECCHHHEEE	50.13	32015554
73	Ubiquitination	VIHFNNPKVQASLSA EEEECCHHHEEEEEC	49.45	32015554
79	Phosphorylation	PKVQASLSANTFAIT HHHEEEEECCEEEEE	19.58	21601212
95	Phosphorylation	HAEAKPITEMLPGIL CCCCCCHHHHHHHHH	24.70	21601212
103	Phosphorylation	EMLPGILSQLGADSL HHHHHHHHHHCCHHH	22.80	21601212
109	Phosphorylation	LSQLGADSLTSLRKL HHHHCCHHHHHHHHH	32.77	27251275
111	Phosphorylation	QLGADSLTSLRKLAE HHCCHHHHHHHHHHH	29.66	27251275
112	Phosphorylation	LGADSLTSLRKLAEQ HCCHHHHHHHHHHHH	31.32	27251275
115	Ubiquitination	DSLTSLRKLAEQFPR HHHHHHHHHHHHCCH	58.29	22817900
115	Methylation	DSLTSLRKLAEQFPR HHHHHHHHHHHHCCH	58.29	-
128	Ubiquitination	PRQVLDSKAPKPEDI CHHHHCCCCCCCCCC	69.26	32015554
128	Acetylation	PRQVLDSKAPKPEDI CHHHHCCCCCCCCCC	69.26	19816289
131	Ubiquitination	VLDSKAPKPEDIDEE HHCCCCCCCCCCCCC	66.93	32015554
153	Phosphorylation	VENFDEASKNEAN-- HHHHHHHHHHCCC--	33.69	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BT3L4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BT3L4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BT3L4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NACA2_HUMAN	NACA2	physical	22939629
ARI1_HUMAN	ARIH1	physical	22863883
ARC1B_HUMAN	ARPC1B	physical	22863883
ARPC5_HUMAN	ARPC5	physical	22863883
NC2B_HUMAN	DR1	physical	22863883
GOPC_HUMAN	GOPC	physical	22863883
HSF1_HUMAN	HSF1	physical	22863883
IST1_HUMAN	IST1	physical	22863883
5NTC_HUMAN	NT5C2	physical	22863883
OXSR1_HUMAN	OXSR1	physical	22863883
PLIN3_HUMAN	PLIN3	physical	22863883
TPD54_HUMAN	TPD52L2	physical	22863883
UBE3A_HUMAN	UBE3A	physical	22863883
TXLNB_HUMAN	TXLNB	physical	25416956
TXLNA_HUMAN	TXLNA	physical	25416956
BTF3_HUMAN	BTF3	physical	26344197
HNRPU_HUMAN	HNRNPU	physical	26344197
NACAM_HUMAN	NACA	physical	26344197
NACA_HUMAN	NACA	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-153, AND MASSSPECTROMETRY.
PubMed: 18669648