DIRA3_HUMAN - dbPTM
DIRA3_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DIRA3_HUMAN
UniProt AC O95661
Protein Name GTP-binding protein Di-Ras3
Gene Name DIRAS3
Organism Homo sapiens (Human).
Sequence Length 229
Subcellular Localization Cell membrane
Lipid-anchor
Cytoplasmic side .
Protein Description
Protein Sequence MGNASFGSKEQKLLKRLRLLPALLILRAFKPHRKIRDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSDDTHREVALNDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKKSQMPNTTEKLLDKCIIM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
45PhosphorylationYRVVVVGTAGVGKST
EEEEEEECCCCCHHH		14.50-
198PhosphorylationLFHMLLNYKKKPTTG
HHHHHHHCCCCCCCC		24.93-
201AcetylationMLLNYKKKPTTGLQE
HHHHCCCCCCCCCCC		43.377665083
203PhosphorylationLNYKKKPTTGLQEPE
HHCCCCCCCCCCCCH		42.2330177828
204PhosphorylationNYKKKPTTGLQEPEK
HCCCCCCCCCCCCHH		44.4130177828
213PhosphorylationLQEPEKKSQMPNTTE
CCCCHHHCCCCCHHH		42.6630177828
218PhosphorylationKKSQMPNTTEKLLDK
HHCCCCCHHHHHHHH		30.3830177828
219PhosphorylationKSQMPNTTEKLLDKC
HCCCCCHHHHHHHHH		37.4530177828
226MethylationTEKLLDKCIIM----
HHHHHHHHHCC----		2.26-
226GeranylgeranylationTEKLLDKCIIM----
HHHHHHHHHCC----		2.26-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DIRA3_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DIRA3_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DIRA3_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
IF2M_HUMANMTIF2physical
26186194
ZNT1_HUMANSLC30A1physical
26186194
GDS1_HUMANRAP1GDS1physical
26186194
RN19B_HUMANRNF19Bphysical
26186194
HECD1_HUMANHECTD1physical
26186194
MDM2_HUMANMDM2physical
26186194
RHOA_HUMANRHOAphysical
26186194
DCA10_HUMANDCAF10physical
26186194
FEZ2_HUMANFEZ2physical
26186194
ZNT1_HUMANSLC30A1physical
28514442
IF2M_HUMANMTIF2physical
28514442
FEZ2_HUMANFEZ2physical
28514442
RN19B_HUMANRNF19Bphysical
28514442
DCA10_HUMANDCAF10physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DIRA3_HUMAN

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Related Literatures of Post-Translational Modification

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