TAF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAF1_HUMAN
• UniProt AC: P21675
• Protein Name: Transcription initiation factor TFIID subunit 1
• Gene Name: TAF1
• Organism: Homo sapiens (Human).
• Sequence Length: 1872
• Subcellular Localization: Nucleus .
• Protein Description: Largest component and core scaffold of the TFIID basal transcription factor complex. [PubMed: 25412659]
• Protein Sequence: MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDDECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDESRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGEKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSEDFHSIAGDSDLDSDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
127	Phosphorylation	ESRRYQQTMGSLQPL HHHHHHHHHHCCCCC	14.15	23663014
130	Phosphorylation	RYQQTMGSLQPLCHS HHHHHHHCCCCCCCC	17.01	23663014
137	Phosphorylation	SLQPLCHSDYDEDDY CCCCCCCCCCCCCCC	36.55	23663014
139	Phosphorylation	QPLCHSDYDEDDYDA CCCCCCCCCCCCCCC	25.01	30576142
143	Ubiquitination	HSDYDEDDYDADCED CCCCCCCCCCCCCCC	40.96	23000965
144	Phosphorylation	SDYDEDDYDADCEDI CCCCCCCCCCCCCCC	25.92	30576142
167	Acetylation	PPPPGPMKKDKDQDS CCCCCCCCCCCCCCC	62.04	25953088
170	Acetylation	PGPMKKDKDQDSITG CCCCCCCCCCCCCCC	67.19	23954790
183	Phosphorylation	TGEKVDFSSSSDSES CCCCCCCCCCCCCCC	25.50	27732954
184	Phosphorylation	GEKVDFSSSSDSESE CCCCCCCCCCCCCCC	33.58	27732954
185	Phosphorylation	EKVDFSSSSDSESEM CCCCCCCCCCCCCCC	36.65	27732954
186	Phosphorylation	KVDFSSSSDSESEMG CCCCCCCCCCCCCCC	47.29	27732954
188	Phosphorylation	DFSSSSDSESEMGPQ CCCCCCCCCCCCCCC	44.99	22210691
189 (in isoform 12)	Phosphorylation	-	56.56	22210691
189 (in isoform 2)	Phosphorylation	-	56.56	22210691
190	Phosphorylation	SSSSDSESEMGPQEA CCCCCCCCCCCCCCC	36.51	27732954
198	Phosphorylation	EMGPQEATQAESEDG CCCCCCCHHCCCCCC	27.79	27732954
198 (in isoform 12)	Phosphorylation	-	27.79	22210691
198 (in isoform 2)	Phosphorylation	-	27.79	22210691
202	Phosphorylation	QEATQAESEDGKLTL CCCHHCCCCCCCEEE	43.96	27732954
237	Ubiquitination	FPEFRPGKVLRFLRL CCCCCCCCHHHHHHH	40.56	-
237 (in isoform 4)	Ubiquitination	-	40.56	-
249	Ubiquitination	LRLFGPGKNVPSVWR HHHHCCCCCHHHHHH	58.88	23000965
249 (in isoform 4)	Ubiquitination	-	58.88	-
253	Phosphorylation	GPGKNVPSVWRSARR CCCCCHHHHHHHHHH	29.99	23403867
258	Ubiquitination	VPSVWRSARRKRKKK HHHHHHHHHHHHHHH	13.51	-
258	Ubiquitination	VPSVWRSARRKRKKK HHHHHHHHHHHHHHH	13.51	-
270	Ubiquitination	KKKHRELIQEEQIQE HHHHHHHHCHHHHHE	4.08	-
270	Ubiquitination	KKKHRELIQEEQIQE HHHHHHHHCHHHHHE	4.08	23000965
287	Phosphorylation	CSVESEVSQKSLWNY CCCCCCCCCHHHCCC	28.04	-
294	Phosphorylation	SQKSLWNYDYAPPPP CCHHHCCCCCCCCCC	9.96	28176443
296	Phosphorylation	KSLWNYDYAPPPPPE HHHCCCCCCCCCCHH	15.62	28176443
307	Phosphorylation	PPPEQCLSDDEITMM CCHHHCCCCCEEEEE	51.12	28176443
312	Phosphorylation	CLSDDEITMMAPVES CCCCCEEEEECCCCH	9.99	28176443
319	Phosphorylation	TMMAPVESKFSQSTG EEECCCCHHHCCCCC	38.95	28176443
322	Phosphorylation	APVESKFSQSTGDID CCCCHHHCCCCCCHH	27.27	23312004
324	Phosphorylation	VESKFSQSTGDIDKV CCHHHCCCCCCHHHC	32.91	29214152
325	Phosphorylation	ESKFSQSTGDIDKVT CHHHCCCCCCHHHCC	31.10	23312004
328	Phosphorylation	FSQSTGDIDKVTDTK HCCCCCCHHHCCCCC	6.13	8625415
330 (in isoform 4)	Ubiquitination	-	47.57	-
335	Ubiquitination	IDKVTDTKPRVAEWR HHHCCCCCCCCEECC	33.37	-
335 (in isoform 4)	Ubiquitination	-	33.37	-
343	Phosphorylation	PRVAEWRYGPARLWY CCCEECCCCCCCHHH	28.65	-
345	Phosphorylation	VAEWRYGPARLWYDM CEECCCCCCCHHHHH	12.79	-
350	Phosphorylation	YGPARLWYDMLGVPE CCCCCHHHHHHCCCC	8.96	-
351	Ubiquitination	GPARLWYDMLGVPED CCCCHHHHHHCCCCC	17.78	-
351	Ubiquitination	GPARLWYDMLGVPED CCCCHHHHHHCCCCC	17.78	-
356	Ubiquitination	WYDMLGVPEDGSGFD HHHHHCCCCCCCCCC	31.96	-
356	Ubiquitination	WYDMLGVPEDGSGFD HHHHHCCCCCCCCCC	31.96	-
364	Phosphorylation	EDGSGFDYGFKLRKT CCCCCCCCCCEECCC	23.38	-
378	Ubiquitination	TEHEPVIKSRMIEEF CCCCCCHHHHHHHHH	32.04	29967540
399	Ubiquitination	NGTDLLADENFLMVT CCCCCCCCCCEEEEE	51.87	29967540
432	Phosphorylation	GTKPQRASLAGWLPS CCCCCHHHHCCCCCC	22.42	28509920
442	Phosphorylation	GWLPSSMTRNAMAYN CCCCCHHHHHHHHHC	23.79	-
501	Phosphorylation	LLEPPVLTLDPNDEN HHCCCEEEECCCCCC	29.37	27251275
521	Phosphorylation	PDEKEEATSNSPSKE CCHHHHHCCCCCCHH	31.55	30278072
522	Phosphorylation	DEKEEATSNSPSKES CHHHHHCCCCCCHHH	42.21	30278072
524	Phosphorylation	KEEATSNSPSKESKK HHHHCCCCCCHHHHH	30.25	30278072
526	Phosphorylation	EATSNSPSKESKKES HHCCCCCCHHHHHHH	49.21	30278072
529	Phosphorylation	SNSPSKESKKESSLK CCCCCHHHHHHHHHH	53.41	22210691
542	Phosphorylation	LKKSRILLGKTGVIK HHHHHHHHCCCCCCC	6.51	18452278
543	Phosphorylation	KKSRILLGKTGVIKE HHHHHHHCCCCCCCC	23.25	18452278
544	Acetylation	KSRILLGKTGVIKEE HHHHHHCCCCCCCCC	41.92	25953088
545	Phosphorylation	SRILLGKTGVIKEEP HHHHHCCCCCCCCCC	34.58	15302935
547	Phosphorylation	ILLGKTGVIKEEPQQ HHHCCCCCCCCCCCC	7.37	18452278
549	Sumoylation	LGKTGVIKEEPQQNM HCCCCCCCCCCCCCC	54.33	-
549	Sumoylation	LGKTGVIKEEPQQNM HCCCCCCCCCCCCCC	54.33	28112733
562	Sumoylation	NMSQPEVKDPWNLSN CCCCCCCCCCCCCCC	57.31	28112733
570	Sumoylation	DPWNLSNDEYYYPKQ CCCCCCCCCCCCCHH	41.73	-
592	Phosphorylation	GGNIIQHSIPAVELR CCCCHHCCCCEEEEC	17.56	-
595	Ubiquitination	IIQHSIPAVELRQPF CHHCCCCEEEECCCC	13.02	21890473
611	Acetylation	PTHMGPIKLRQFHRP CCCCCCCCCEECCCC	40.53	25953088
613	Phosphorylation	HMGPIKLRQFHRPPL CCCCCCCEECCCCCC	31.92	-
701	Ubiquitination	VGMATKIKNYYKRKP ECCHHHHHHHHHCCC	40.22	21890473
701	Ubiquitination	VGMATKIKNYYKRKP ECCHHHHHHHHHCCC	40.22	21890473
701	Ubiquitination	VGMATKIKNYYKRKP ECCHHHHHHHHHCCC	40.22	21890473
701 (in isoform 1)	Ubiquitination	-	40.22	21890473
701 (in isoform 3)	Ubiquitination	-	40.22	21890473
701 (in isoform 4)	Ubiquitination	-	40.22	21890473
705	Acetylation	TKIKNYYKRKPGKDP HHHHHHHHCCCCCCC	43.52	71391
705	Ubiquitination	TKIKNYYKRKPGKDP HHHHHHHHCCCCCCC	43.52	-
722	Ubiquitination	PDCKYGETVYCHTSP CCCCCCCEEEEECCC	16.65	21890473
722	Ubiquitination	PDCKYGETVYCHTSP CCCCCCCEEEEECCC	16.65	21890473
722 (in isoform 2)	Ubiquitination	-	16.65	21890473
832	Ubiquitination	IRMEDIKKAFPSHSE CCHHHHHHHCCCCCH	56.44	29967540
853	Ubiquitination	LKLCADFKRTGMDSN HHHHHHHHHHCCCCC	49.99	29967540
855	Phosphorylation	LCADFKRTGMDSNWW HHHHHHHHCCCCCEE	37.13	21712546
859	Phosphorylation	FKRTGMDSNWWVLKS HHHHCCCCCEEEEEC	26.00	24260401
876	Phosphorylation	RLPTEEEIRAMVSPE CCCCHHHHHHHCCHH	3.73	-
888	Phosphorylation	SPEQCCAYYSMIAAE CHHHHHHHHHHHHHH	5.12	20736484
889	Phosphorylation	PEQCCAYYSMIAAEQ HHHHHHHHHHHHHHH	3.53	20736484
907	Phosphorylation	DAGYGEKSFFAPEEE HCCCCCCCCCCCCCC	22.69	27134283
909	Phosphorylation	GYGEKSFFAPEEENE CCCCCCCCCCCCCCH	16.69	-
910	Phosphorylation	YGEKSFFAPEEENEE CCCCCCCCCCCCCHH	14.48	-
986	Ubiquitination	KEPQPVKKTVTGTDA CCCCCCCEEECCCHH	48.76	29967540
987	Phosphorylation	EPQPVKKTVTGTDAD CCCCCCEEECCCHHH	19.99	21406692
989	Phosphorylation	QPVKKTVTGTDADLR CCCCEEECCCHHHHH	39.33	21406692
991	Phosphorylation	VKKTVTGTDADLRRL CCEEECCCHHHHHHH	20.74	21406692
1007	Ubiquitination	LKNAKQLLRKFGVPE HHHHHHHHHHHCCCH	5.32	29967540
1009	Ubiquitination	NAKQLLRKFGVPEEE HHHHHHHHHCCCHHH	46.57	29967540
1030	Ubiquitination	WEVIDVVRTMSTEQA CHHCCHHECCCHHHH	25.26	29967540
1054	Phosphorylation	FARGSRFSVAEHQER HHCCCCCCHHHHHHH	21.21	28555341
1075	Phosphorylation	RIFDLQNKVLSSTEV HHHHHHHHHHCCCEE	31.43	-
1111	Ubiquitination	IENMLQNKKTSSQLS HHHHHHHHHHHHHHH	44.46	29967540
1132	Ubiquitination	ERKELQRMLLAAGSA HHHHHHHHHHHHHHC	2.01	29967540
1138	Phosphorylation	RMLLAAGSAASGNNH HHHHHHHHCCCCCCC	18.88	30108239
1141	Phosphorylation	LAAGSAASGNNHRDD HHHHHCCCCCCCCCC	41.59	30108239
1150	Phosphorylation	NNHRDDDTASVTSLN CCCCCCCCCCCEECC	28.03	30266825
1152	Phosphorylation	HRDDDTASVTSLNSS CCCCCCCCCEECCCC	28.20	30266825
1154	Phosphorylation	DDDTASVTSLNSSAT CCCCCCCEECCCCHH	25.63	23401153
1155	Phosphorylation	DDTASVTSLNSSATG CCCCCCEECCCCHHC	24.33	30266825
1158	Phosphorylation	ASVTSLNSSATGRCL CCCEECCCCHHCCEE	27.00	30266825
1159	Phosphorylation	SVTSLNSSATGRCLK CCEECCCCHHCCEEE	28.86	23663014
1161	Phosphorylation	TSLNSSATGRCLKIY EECCCCHHCCEEEEE	27.40	30266825
1168	Phosphorylation	TGRCLKIYRTFRDEE HCCEEEEEEEEECCC	11.30	29978859
1171	Phosphorylation	CLKIYRTFRDEEGKE EEEEEEEEECCCCCE	7.39	18452278
1173	Phosphorylation	KIYRTFRDEEGKEYV EEEEEEECCCCCEEE	54.85	-
1175	Phosphorylation	YRTFRDEEGKEYVRC EEEEECCCCCEEEEE	78.74	20068231
1176	Phosphorylation	RTFRDEEGKEYVRCE EEEECCCCCEEEEEE	26.50	18452278
1179	Phosphorylation	RDEEGKEYVRCETVR ECCCCCEEEEEEECC	9.18	-
1208	Ubiquitination	KDEEFIRKFALFDEQ CCHHHHHHHHHCCHH	30.12	29967540
1229	Ubiquitination	KERRRIQEQLRRLKR HHHHHHHHHHHHHHH	49.57	29967540
1244	Acetylation	NQEKEKLKGPPEKKP HHHHHHHCCCCCCCC	79.16	30583719
1282	Phosphorylation	TNKFCPLYYQTNAPP CCCCCCEEECCCCCC	4.43	25850435
1283	Phosphorylation	NKFCPLYYQTNAPPS CCCCCEEECCCCCCC	19.28	25850435
1285	Phosphorylation	FCPLYYQTNAPPSNP CCCEEECCCCCCCCC	19.75	25850435
1290	Phosphorylation	YQTNAPPSNPVAMTE ECCCCCCCCCCCCCH	53.35	25850435
1306	Phosphorylation	QEEELEKTVIHNDNE HHHHHHHHEECCCCC	18.47	25159151
1327	Acetylation	GTKIVLGKQLIESAD CEEEEECHHHHHCHH	37.46	25953088
1327	Phosphorylation	GTKIVLGKQLIESAD CEEEEECHHHHHCHH	37.46	-
1327	Ubiquitination	GTKIVLGKQLIESAD CEEEEECHHHHHCHH	37.46	29967540
1332	Phosphorylation	LGKQLIESADEVRRK ECHHHHHCHHHHHHH	33.74	21815630
1340	Phosphorylation	ADEVRRKSLVLKFPK HHHHHHHHHHHHCCH	23.15	28450419
1347	Acetylation	SLVLKFPKQQLPPKK HHHHHCCHHHCCCCC	54.53	30583707
1348	Ubiquitination	LVLKFPKQQLPPKKK HHHHCCHHHCCCCCC	50.73	29967540
1354	Acetylation	KQQLPPKKKRRVGTT HHHCCCCCCCCCCCE	58.23	30583713
1360	Phosphorylation	KKKRRVGTTVHCDYL CCCCCCCCEEECCCC	23.84	20044836
1361	Phosphorylation	KKRRVGTTVHCDYLN CCCCCCCEEECCCCC	11.43	-
1366	Phosphorylation	GTTVHCDYLNRPHKS CCEEECCCCCCCCCC	15.98	20044836
1379	Phosphorylation	KSIHRRRTDPMVTLS CCHHHCCCCCCCCHH	42.52	-
1381	Phosphorylation	IHRRRTDPMVTLSSI HHHCCCCCCCCHHHH	20.66	-
1384	Phosphorylation	RRTDPMVTLSSILES CCCCCCCCHHHHHHH	18.05	-
1387	Phosphorylation	DPMVTLSSILESIIN CCCCCHHHHHHHHHH	34.01	-
1391	Phosphorylation	TLSSILESIINDMRD CHHHHHHHHHHHHHC	25.89	20044836
1402	Phosphorylation	DMRDLPNTYPFHTPV HHHCCCCCCCCCCCC	30.54	28348404
1407	Phosphorylation	PNTYPFHTPVNAKVV CCCCCCCCCCCCHHH	29.34	24719451
1412	Acetylation	FHTPVNAKVVKDYYK CCCCCCCHHHHHHHH	42.21	25953088
1412	Phosphorylation	FHTPVNAKVVKDYYK CCCCCCCHHHHHHHH	42.21	-
1422	Phosphorylation	KDYYKIITRPMDLQT HHHHHHHCCCCCHHH	31.99	23403867
1429	Phosphorylation	TRPMDLQTLRENVRK CCCCCHHHHHHHHHH	34.77	23403867
1541	Phosphorylation	KKFVPDYYKVIVNPM CCCCCCCEEEECCCC	13.22	-
1562	Phosphorylation	KNISKHKYQSRESFL HHHHHHHHHCHHHHH	16.08	-
1564	Phosphorylation	ISKHKYQSRESFLDD HHHHHHHCHHHHHHH	34.62	-
1633	Phosphorylation	LEEAELESLDPMTPG HHHHHHHCCCCCCCC	51.18	21406692
1638	Phosphorylation	LESLDPMTPGPYTPQ HHCCCCCCCCCCCCC	30.40	28348404
1642	Phosphorylation	DPMTPGPYTPQPPDL CCCCCCCCCCCCCCC	36.65	28348404
1643	Phosphorylation	PMTPGPYTPQPPDLY CCCCCCCCCCCCCCC	20.69	28348404
1654	O-linked_Glycosylation	PDLYDTNTSLSMSRD CCCCCCCCCCCCCCC	32.89	OGP
1654	Phosphorylation	PDLYDTNTSLSMSRD CCCCCCCCCCCCCCC	32.89	-
1663	Phosphorylation	LSMSRDASVFQDESN CCCCCCCCCCCCCCC	27.96	20068231
1669	Phosphorylation	ASVFQDESNMSVLDI CCCCCCCCCCEEEEC	46.23	20068231
1672	Phosphorylation	FQDESNMSVLDIPSA CCCCCCCEEEECCCC	24.63	30266825
1678	Phosphorylation	MSVLDIPSATPEKQV CEEEECCCCCCCCCC	45.14	30266825
1680	Phosphorylation	VLDIPSATPEKQVTQ EEECCCCCCCCCCCC	36.00	30266825
1692	Phosphorylation	VTQEGEDGDGDLADE CCCCCCCCCCCCCCC	36.18	-
1695	Phosphorylation	EGEDGDGDLADEEEG CCCCCCCCCCCCCCC	43.34	-
1697 (in isoform 3)	Phosphorylation	-	27.23	25849741
1700 (in isoform 4)	Phosphorylation	-	63.37	25849741
1700 (in isoform 5)	Phosphorylation	-	63.37	25849741
1702 (in isoform 9)	Phosphorylation	-	34.17	25849741
1703	Phosphorylation	LADEEEGTVQQPQAS CCCCCCCCCCCCHHH	20.58	18452278
1750	Phosphorylation	LSESGSDSDVGSGGI EECCCCCCCCCCCCC	35.57	24275569
1769	Phosphorylation	PRMLQENTRMDMENE CCCCCCCCCCCCCCH	26.98	29759185
1778	Phosphorylation	MDMENEESMMSYEGD CCCCCHHHCCCCCCC	17.38	-
1778 (in isoform 6)	Phosphorylation	-	17.38	27732954
1780 (in isoform 7)	Phosphorylation	-	5.55	27732954
1781	Phosphorylation	ENEESMMSYEGDGGE CCHHHCCCCCCCCCC	16.05	-
1781 (in isoform 6)	Phosphorylation	-	16.05	27732954
1782	Phosphorylation	NEESMMSYEGDGGEA CHHHCCCCCCCCCCC	13.16	28985074
1782 (in isoform 6)	Phosphorylation	-	13.16	27732954
1783 (in isoform 7)	Phosphorylation	-	43.43	27732954
1784 (in isoform 7)	Phosphorylation	-	30.54	27732954
1790 (in isoform 6)	Phosphorylation	-	17.49	27732954
1792 (in isoform 7)	Phosphorylation	-	28.41	27732954
1799	Phosphorylation	GLEDSNISYGSYEEP CCCCCCCCCCCCCCC	27.91	-
1802	Phosphorylation	DSNISYGSYEEPDPK CCCCCCCCCCCCCCC	22.57	-
1809 (in isoform 3)	Phosphorylation	-	64.81	27732954
1812 (in isoform 3)	Phosphorylation	-	34.61	27732954
1812 (in isoform 5)	Phosphorylation	-	34.61	27732954
1813 (in isoform 3)	Phosphorylation	-	57.12	27732954
1814 (in isoform 9)	Phosphorylation	-	42.13	27732954
1815 (in isoform 5)	Phosphorylation	-	23.12	27732954
1816 (in isoform 5)	Phosphorylation	-	31.27	27732954
1817 (in isoform 9)	Phosphorylation	-	7.83	27732954
1818 (in isoform 9)	Phosphorylation	-	22.32	27732954
1821 (in isoform 3)	Phosphorylation	-	34.28	27732954
1823	Phosphorylation	SFSSIGGYEVSEEEE CCHHCCCEECCCHHC	14.14	28985074
1824 (in isoform 5)	Phosphorylation	-	42.73	27732954
1826	Phosphorylation	SIGGYEVSEEEEDEE HCCCEECCCHHCCHH	27.61	28112733
1826 (in isoform 9)	Phosphorylation	-	27.61	27732954
1849	Phosphorylation	SVLSQVHLSEDEEDS CHHHEEECCCCCCCC	6.70	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TAF1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAF1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBF1_HUMAN	UBTF	physical	12498690
CCND1_HUMAN	CCND1	physical	9926939
RB_HUMAN	RB1	genetic	11126356
TAF7_HUMAN	TAF7	physical	11592977
TAF4_HUMAN	TAF4	physical	11564872
T2FA_HUMAN	GTF2F1	physical	8625415
T2FA_HUMAN	GTF2F1	physical	7590250
TAF2_HUMAN	TAF2	physical	10469661
T2FA_HUMAN	GTF2F1	physical	9858607
RB_HUMAN	RB1	physical	9858607
TBP_HUMAN	TBP	physical	9858607
FOS_HUMAN	FOS	physical	8065335
T2FA_HUMAN	GTF2F1	physical	9482861
TF2AA_HUMAN	GTF2A1	physical	11278496
PAX6_HUMAN	PAX6	physical	10359315
P53_HUMAN	TP53	physical	10359315
RB_HUMAN	RB1	physical	9242374
RBL1_HUMAN	RBL1	physical	9242374
RBL2_HUMAN	RBL2	physical	9242374
TBP_HUMAN	TBP	physical	9660973
CSK21_HUMAN	CSNK2A1	physical	18548200
TAF2_HUMAN	TAF2	physical	15870300
TBP_HUMAN	TBP	physical	15870300
H31_HUMAN	HIST1H3A	physical	20393127
TBP_HUMAN	TBP	physical	7597030
PAX3_HUMAN	PAX3	physical	21145483
P53_HUMAN	TP53	physical	15053879
T2FA_HUMAN	GTF2F1	physical	15053879
TAF5_HUMAN	TAF5	physical	22939629
TAF6_HUMAN	TAF6	physical	22939629
TAF4_HUMAN	TAF4	physical	22939629
TAF2_HUMAN	TAF2	physical	22939629
TAF7_HUMAN	TAF7	physical	22939629
TAF9B_HUMAN	TAF9B	physical	22939629
TAF3_HUMAN	TAF3	physical	22939629
H11_HUMAN	HIST1H1A	physical	21145483
TAF3_HUMAN	TAF3	physical	26344197
TAF5_HUMAN	TAF5	physical	26344197
TAF13_HUMAN	TAF13	physical	29111974
TAF11_HUMAN	TAF11	physical	29111974
TAF1_HUMAN	TAF1	physical	29111974
TAF2_HUMAN	TAF2	physical	29111974
TAF3_HUMAN	TAF3	physical	29111974
TAF4_HUMAN	TAF4	physical	29111974
TAF4B_HUMAN	TAF4B	physical	29111974
TAF5_HUMAN	TAF5	physical	29111974
TAF6_HUMAN	TAF6	physical	29111974
TAF8_HUMAN	TAF8	physical	29111974
TAF9_HUMAN	TAF9	physical	29111974
TAF9B_HUMAN	TAF9B	physical	29111974
TAF10_HUMAN	TAF10	physical	29111974
TBP_HUMAN	TBP	physical	29111974

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 314250: Dystonia 3, torsion, X-linked (DYT3)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1826, AND MASSSPECTROMETRY.
PubMed: 19690332

"TAFII250 is a bipartite protein kinase that phosphorylates the basetranscription factor RAP74.";
Dikstein R., Ruppert S., Tjian R.;
Cell 84:781-790(1996).
Cited for: FUNCTION, PHOSPHORYLATION AT SER-137 AND SER-307, AND ATP-BINDING.
PubMed: 8625415