dbPTM

UBF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UBF1_HUMAN
UniProt AC	P17480
Protein Name	Nucleolar transcription factor 1
Gene Name	UBTF
Organism	Homo sapiens (Human).
Sequence Length	764
Subcellular Localization	Nucleus, nucleolus .
Protein Description	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element..
Protein Sequence	MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MNGEADCP -------CCCCCCCC	15.23	19413330
9	Phosphorylation	NGEADCPTDLEMAAP CCCCCCCCCHHHHCC	60.59	23401153
17	Ubiquitination	DLEMAAPKGQDRWSQ CHHHHCCCCCCCCCH	65.56	29967540
23	Phosphorylation	PKGQDRWSQEDMLTL CCCCCCCCHHHHHHH	25.28	23401153
29	Phosphorylation	WSQEDMLTLLECMKN CCHHHHHHHHHHHHH	23.74	23532336
33	Glutathionylation	DMLTLLECMKNNLPS HHHHHHHHHHHCCCC	4.79	22555962
35	Ubiquitination	LTLLECMKNNLPSND HHHHHHHHHCCCCCC	55.10	29967540
44	Phosphorylation	NLPSNDSSKFKTTES CCCCCCCHHCCCCCC	45.00	-
45	Acetylation	LPSNDSSKFKTTESH CCCCCCHHCCCCCCC	55.63	25953088
45	Ubiquitination	LPSNDSSKFKTTESH CCCCCCHHCCCCCCC	55.63	29967540
47	Ubiquitination	SNDSSKFKTTESHMD CCCCHHCCCCCCCCC	59.27	29967540
48	Phosphorylation	NDSSKFKTTESHMDW CCCHHCCCCCCCCCH	38.64	29116813
57	Ubiquitination	ESHMDWEKVAFKDFS CCCCCHHHHHCCCCC	34.31	29967540
61	Acetylation	DWEKVAFKDFSGDMC CHHHHHCCCCCCCCC	48.39	25953088
61	Ubiquitination	DWEKVAFKDFSGDMC CHHHHHCCCCCCCCC	48.39	29967540
64	Phosphorylation	KVAFKDFSGDMCKLK HHHCCCCCCCCCEEE	43.97	29496963
69	Ubiquitination	DFSGDMCKLKWVEIS CCCCCCCEEEEEEEC	46.60	29967540
71	Acetylation	SGDMCKLKWVEISNE CCCCCEEEEEEECHH	34.39	26051181
71	Ubiquitination	SGDMCKLKWVEISNE CCCCCEEEEEEECHH	34.39	33845483
71 (in isoform 1)	Ubiquitination	-	34.39	21890473
71 (in isoform 2)	Ubiquitination	-	34.39	21890473
97	Ubiquitination	LDAQEHVKNPYKGKK HHHHHHCCCCCCCCC	54.86	29967540
107	Ubiquitination	YKGKKLKKHPDFPKK CCCCCCCCCCCCCCC	71.46	29967540
114	Sumoylation	KHPDFPKKPLTPYFR CCCCCCCCCCCHHHH	45.56	-
114	Acetylation	KHPDFPKKPLTPYFR CCCCCCCCCCCHHHH	45.56	23749302
114	Sumoylation	KHPDFPKKPLTPYFR CCCCCCCCCCCHHHH	45.56	-
114	Ubiquitination	KHPDFPKKPLTPYFR CCCCCCCCCCCHHHH	45.56	-
117	Phosphorylation	DFPKKPLTPYFRFFM CCCCCCCCHHHHHHH	25.19	11741541
119	Phosphorylation	PKKPLTPYFRFFMEK CCCCCCHHHHHHHHH	11.36	23312004
126	Ubiquitination	YFRFFMEKRAKYAKL HHHHHHHHHHHHHHH	45.96	23000965
129	Ubiquitination	FFMEKRAKYAKLHPE HHHHHHHHHHHHCHH	50.18	23000965
132	Acetylation	EKRAKYAKLHPEMSN HHHHHHHHHCHHHCC	44.21	25953088
132	Ubiquitination	EKRAKYAKLHPEMSN HHHHHHHHHCHHHCC	44.21	23000965
132 (in isoform 1)	Ubiquitination	-	44.21	21890473
132 (in isoform 2)	Ubiquitination	-	44.21	21890473
144	Ubiquitination	MSNLDLTKILSKKYK HCCCCHHHHHHHHHH	49.28	29967540
147	Phosphorylation	LDLTKILSKKYKELP CCHHHHHHHHHHHCC	30.49	20068231
150	Phosphorylation	TKILSKKYKELPEKK HHHHHHHHHHCCHHH	17.27	-
151	Ubiquitination	KILSKKYKELPEKKK HHHHHHHHHCCHHHH	62.75	-
156	Ubiquitination	KYKELPEKKKMKYIQ HHHHCCHHHHCHHHH	56.61	22817900
157	Ubiquitination	YKELPEKKKMKYIQD HHHCCHHHHCHHHHH	57.34	22817900
158	Ubiquitination	KELPEKKKMKYIQDF HHCCHHHHCHHHHHH	52.25	22817900
160	Sumoylation	LPEKKKMKYIQDFQR CCHHHHCHHHHHHHH	48.35	-
160	Sumoylation	LPEKKKMKYIQDFQR CCHHHHCHHHHHHHH	48.35	-
160	Ubiquitination	LPEKKKMKYIQDFQR CCHHHHCHHHHHHHH	48.35	21890473
160 (in isoform 1)	Ubiquitination	-	48.35	21890473
160 (in isoform 2)	Ubiquitination	-	48.35	21890473
169	Ubiquitination	IQDFQREKQEFERNL HHHHHHHHHHHHHHH	58.26	29967540
191	Ubiquitination	PDLIQNAKKSDIPEK HHHHHHHHHCCCCCC	61.43	29967540
193	Phosphorylation	LIQNAKKSDIPEKPK HHHHHHHCCCCCCCC	39.81	27251275
198	Ubiquitination	KKSDIPEKPKTPQQL HHCCCCCCCCCHHHH	46.59	29967540
200	Ubiquitination	SDIPEKPKTPQQLWY CCCCCCCCCHHHHEE	81.53	29967540
201	O-linked_Glycosylation	DIPEKPKTPQQLWYT CCCCCCCCHHHHEEE	34.55	23301498
201	Phosphorylation	DIPEKPKTPQQLWYT CCCCCCCCHHHHEEE	34.55	25159151
207	Phosphorylation	KTPQQLWYTHEKKVY CCHHHHEEEECCEEE	13.55	23312004
208	Phosphorylation	TPQQLWYTHEKKVYL CHHHHEEEECCEEEE	16.39	25159151
208 (in isoform 2)	Phosphorylation	-	16.39	25159151
211	Ubiquitination	QLWYTHEKKVYLKVR HHEEEECCEEEEEEC	39.68	32015554
212	Ubiquitination	LWYTHEKKVYLKVRP HEEEECCEEEEEECC	32.88	29967540
216	Ubiquitination	HEKKVYLKVRPDATT ECCEEEEEECCCCCH	20.64	21890473
216 (in isoform 2)	Ubiquitination	-	20.64	21890473
224	Ubiquitination	VRPDATTKEVKDSLG ECCCCCHHHHHHHHH	57.04	29967540
229	Ubiquitination	TTKEVKDSLGKQWSQ CHHHHHHHHHHHHHH	33.05	21890473
229 (in isoform 2)	Ubiquitination	-	33.05	21890473
232	Trimethylation	EVKDSLGKQWSQLSD HHHHHHHHHHHHHCH	54.62	-
232	Methylation	EVKDSLGKQWSQLSD HHHHHHHHHHHHHCH	54.62	-
232	Ubiquitination	EVKDSLGKQWSQLSD HHHHHHHHHHHHHCH	54.62	29967540
238	Phosphorylation	GKQWSQLSDKKRLKW HHHHHHHCHHHHHHH	39.48	25159151
240	Ubiquitination	QWSQLSDKKRLKWIH HHHHHCHHHHHHHHH	36.10	29967540
242	Ubiquitination	SQLSDKKRLKWIHKA HHHCHHHHHHHHHHH	47.44	21963094
242 (in isoform 2)	Ubiquitination	-	47.44	21890473
244	Ubiquitination	LSDKKRLKWIHKALE HCHHHHHHHHHHHHH	48.40	-
247	Ubiquitination	KKRLKWIHKALEQRK HHHHHHHHHHHHHHH	14.28	22817900
248	Ubiquitination	KRLKWIHKALEQRKE HHHHHHHHHHHHHHH	45.60	29967540
254	Trimethylation	HKALEQRKEYEEIMR HHHHHHHHHHHHHHH	65.43	-
254	Methylation	HKALEQRKEYEEIMR HHHHHHHHHHHHHHH	65.43	-
254	Ubiquitination	HKALEQRKEYEEIMR HHHHHHHHHHHHHHH	65.43	29967540
262	Ubiquitination	EYEEIMRDYIQKHPE HHHHHHHHHHHHCCC	27.75	29967540
263	Phosphorylation	YEEIMRDYIQKHPEL HHHHHHHHHHHCCCC	8.55	28152594
266	Acetylation	IMRDYIQKHPELNIS HHHHHHHHCCCCCCC	52.12	26051181
266	Ubiquitination	IMRDYIQKHPELNIS HHHHHHHHCCCCCCC	52.12	23000965
266 (in isoform 1)	Ubiquitination	-	52.12	21890473
273	Phosphorylation	KHPELNISEEGITKS HCCCCCCCCCCCCHH	28.64	25159151
278	Phosphorylation	NISEEGITKSTLTKA CCCCCCCCHHHHHHH	29.78	30576142
279	Acetylation	ISEEGITKSTLTKAE CCCCCCCHHHHHHHH	39.25	25953088
279	Sumoylation	ISEEGITKSTLTKAE CCCCCCCHHHHHHHH	39.25	-
279	Ubiquitination	ISEEGITKSTLTKAE CCCCCCCHHHHHHHH	39.25	21906983
279 (in isoform 1)	Ubiquitination	-	39.25	21890473
284	Sumoylation	ITKSTLTKAERQLKD CCHHHHHHHHHHHHH	51.90	-
284	Acetylation	ITKSTLTKAERQLKD CCHHHHHHHHHHHHH	51.90	23749302
284	Sumoylation	ITKSTLTKAERQLKD CCHHHHHHHHHHHHH	51.90	-
284	Ubiquitination	ITKSTLTKAERQLKD CCHHHHHHHHHHHHH	51.90	22817900
296	Ubiquitination	LKDKFDGRPTKPPPN HHHCCCCCCCCCCCC	37.24	32015554
299	Acetylation	KFDGRPTKPPPNSYS CCCCCCCCCCCCCHH	59.20	25953088
299	Ubiquitination	KFDGRPTKPPPNSYS CCCCCCCCCCCCCHH	59.20	29967540
301	Ubiquitination	DGRPTKPPPNSYSLY CCCCCCCCCCCHHHH	42.11	29967540
306	Phosphorylation	KPPPNSYSLYCAELM CCCCCCHHHHHHHHH	16.81	-
308	Phosphorylation	PPNSYSLYCAELMAN CCCCHHHHHHHHHHC	5.44	-
314	Ubiquitination	LYCAELMANMKDVPS HHHHHHHHCCCCCCC	26.11	29967540
315	Ubiquitination	YCAELMANMKDVPST HHHHHHHCCCCCCCC	24.87	29967540
321	Phosphorylation	ANMKDVPSTERMVLC HCCCCCCCCHHHHHH	42.63	29978859
322	Phosphorylation	NMKDVPSTERMVLCS CCCCCCCCHHHHHHH	22.88	29978859
329	Phosphorylation	TERMVLCSQQWKLLS CHHHHHHHHHHHHHH	22.65	29978859
333	Acetylation	VLCSQQWKLLSQKEK HHHHHHHHHHHHHHH	34.90	25953088
333	Ubiquitination	VLCSQQWKLLSQKEK HHHHHHHHHHHHHHH	34.90	32015554
336	Phosphorylation	SQQWKLLSQKEKDAY HHHHHHHHHHHHHHH	50.03	-
338	Ubiquitination	QWKLLSQKEKDAYHK HHHHHHHHHHHHHHH	64.45	29967540
341	Ubiquitination	LLSQKEKDAYHKKCD HHHHHHHHHHHHHHH	54.15	29967540
347	Ubiquitination	KDAYHKKCDQKKKDY HHHHHHHHHHHCCHH	8.81	29967540
351	Ubiquitination	HKKCDQKKKDYEVEL HHHHHHHCCHHHHHH	45.29	29967540
352	2-Hydroxyisobutyrylation	KKCDQKKKDYEVELL HHHHHHCCHHHHHHH	73.00	-
352	Acetylation	KKCDQKKKDYEVELL HHHHHHCCHHHHHHH	73.00	21546905
352	Phosphorylation	KKCDQKKKDYEVELL HHHHHHCCHHHHHHH	73.00	33259812
352	Ubiquitination	KKCDQKKKDYEVELL HHHHHHCCHHHHHHH	73.00	29967540
364	Phosphorylation	ELLRFLESLPEEEQQ HHHHHHHHCCHHHHH	51.91	25849741
378	Ubiquitination	QRVLGEEKMLNINKK HHHHCHHHHHCCCHH	44.37	29967540
384	2-Hydroxyisobutyrylation	EKMLNINKKQATSPA HHHHCCCHHHCCCCC	42.33	-
384	Acetylation	EKMLNINKKQATSPA HHHHCCCHHHCCCCC	42.33	25953088
384	Ubiquitination	EKMLNINKKQATSPA HHHHCCCHHHCCCCC	42.33	29967540
385	Acetylation	KMLNINKKQATSPAS HHHCCCHHHCCCCCC	40.45	19813169
385	Ubiquitination	KMLNINKKQATSPAS HHHCCCHHHCCCCCC	40.45	-
388	Phosphorylation	NINKKQATSPASKKP CCCHHHCCCCCCCCC	32.52	28176443
389	Phosphorylation	INKKQATSPASKKPA CCHHHCCCCCCCCCC	22.83	23401153
392	Phosphorylation	KQATSPASKKPAQEG HHCCCCCCCCCCCCC	44.59	23403867
393	Acetylation	QATSPASKKPAQEGG HCCCCCCCCCCCCCC	65.95	25953088
394	Acetylation	ATSPASKKPAQEGGK CCCCCCCCCCCCCCC	42.99	12435135
401	Acetylation	KPAQEGGKGGSEKPK CCCCCCCCCCCCCCC	71.59	26051181
406	Acetylation	GGKGGSEKPKRPVSA CCCCCCCCCCCCCEE	58.50	12435143
412	Phosphorylation	EKPKRPVSAMFIFSE CCCCCCCEEEEECCH	19.39	25159151
418	Phosphorylation	VSAMFIFSEEKRRQL CEEEEECCHHHHHHH	39.78	24732914
421	Ubiquitination	MFIFSEEKRRQLQEE EEECCHHHHHHHHHH	49.15	29967540
427	Ubiquitination	EKRRQLQEERPELSE HHHHHHHHHCCCCCH	65.65	24816145
429	Methylation	RRQLQEERPELSESE HHHHHHHCCCCCHHH	29.28	12018527
433	Phosphorylation	QEERPELSESELTRL HHHCCCCCHHHHHHH	37.10	23401153
435	Phosphorylation	ERPELSESELTRLLA HCCCCCHHHHHHHHH	34.23	30266825
438	Phosphorylation	ELSESELTRLLARMW CCCHHHHHHHHHHHH	18.41	29255136
443	Methylation	ELTRLLARMWNDLSE HHHHHHHHHHHHHCH	30.53	12018535
443	Ubiquitination	ELTRLLARMWNDLSE HHHHHHHHHHHHHCH	30.53	32142685
449	O-linked_Glycosylation	ARMWNDLSEKKKAKY HHHHHHHCHHHHHHH	50.67	23301498
449	Phosphorylation	ARMWNDLSEKKKAKY HHHHHHHCHHHHHHH	50.67	25159151
451	2-Hydroxyisobutyrylation	MWNDLSEKKKAKYKA HHHHHCHHHHHHHHH	57.08	-
452	Ubiquitination	WNDLSEKKKAKYKAR HHHHCHHHHHHHHHH	54.64	-
456	Phosphorylation	SEKKKAKYKAREAAL CHHHHHHHHHHHHHH	18.10	25884760
464	Sumoylation	KAREAALKAQSERKP HHHHHHHHHHHHCCC	39.39	-
464	Acetylation	KAREAALKAQSERKP HHHHHHHHHHHHCCC	39.39	25953088
464	Sumoylation	KAREAALKAQSERKP HHHHHHHHHHHHCCC	39.39	-
464	Ubiquitination	KAREAALKAQSERKP HHHHHHHHHHHHCCC	39.39	24816145
480	Ubiquitination	GEREERGKLPESPKR CCHHHCCCCCCCHHH	68.07	32142685
484	Phosphorylation	ERGKLPESPKRAEEI HCCCCCCCHHHHHHH	33.51	29255136
486	2-Hydroxyisobutyrylation	GKLPESPKRAEEIWQ CCCCCCHHHHHHHHH	73.79	-
495	Phosphorylation	AEEIWQQSVIGDYLA HHHHHHHHHHHHHHH	10.70	23312004
500	Phosphorylation	QQSVIGDYLARFKND HHHHHHHHHHHHCHH	9.31	24732914
524	Acetylation	MTWNNMEKKEKLMWI HHHCCHHHHHHHHHH	56.30	25953088
527	2-Hydroxyisobutyrylation	NNMEKKEKLMWIKKA CCHHHHHHHHHHHHH	53.15	-
546	Phosphorylation	KRYERELSEMRAPPA HHHHHHHHHCCCCCC	25.29	21815630
555	Phosphorylation	MRAPPAATNSSKKMK CCCCCCCCCCCCCCC	37.43	27251275
557	Phosphorylation	APPAATNSSKKMKFQ CCCCCCCCCCCCCCC	38.90	25849741
557	Ubiquitination	APPAATNSSKKMKFQ CCCCCCCCCCCCCCC	38.90	32015554
558	Phosphorylation	PPAATNSSKKMKFQG CCCCCCCCCCCCCCC	38.06	27251275
559	2-Hydroxyisobutyrylation	PAATNSSKKMKFQGE CCCCCCCCCCCCCCC	57.62	-
559	Acetylation	PAATNSSKKMKFQGE CCCCCCCCCCCCCCC	57.62	25953088
575	Phosphorylation	KKPPMNGYQKFSQEL CCCCCCHHHHHHHHH	11.97	29759185
584	Phosphorylation	KFSQELLSNGELNHL HHHHHHHHCCCCCCC	56.25	25159151
587	Ubiquitination	QELLSNGELNHLPLK HHHHHCCCCCCCCHH	51.12	29967540
594	2-Hydroxyisobutyrylation	ELNHLPLKERMVEIG CCCCCCHHHHHHHHH	41.14	-
594	Acetylation	ELNHLPLKERMVEIG CCCCCCHHHHHHHHH	41.14	26051181
594	Ubiquitination	ELNHLPLKERMVEIG CCCCCCHHHHHHHHH	41.14	32015554
601	Phosphorylation	KERMVEIGSRWQRIS HHHHHHHHHHHHHHH	9.54	32645325
602	Phosphorylation	ERMVEIGSRWQRISQ HHHHHHHHHHHHHHH	35.69	19664994
608	Phosphorylation	GSRWQRISQSQKEHY HHHHHHHHHHHHHHH	26.43	23312004
609	Ubiquitination	SRWQRISQSQKEHYK HHHHHHHHHHHHHHH	47.73	29967540
610	Phosphorylation	RWQRISQSQKEHYKK HHHHHHHHHHHHHHH	36.11	23312004
615	Ubiquitination	SQSQKEHYKKLAEEQ HHHHHHHHHHHHHHH	15.77	24816145
621	Ubiquitination	HYKKLAEEQQKQYKV HHHHHHHHHHHHHHH	53.34	24816145
624	Acetylation	KLAEEQQKQYKVHLD HHHHHHHHHHHHHHH	56.12	26051181
624	Ubiquitination	KLAEEQQKQYKVHLD HHHHHHHHHHHHHHH	56.12	29967540
627	Ubiquitination	EEQQKQYKVHLDLWV HHHHHHHHHHHHHHH	22.23	-
632	Ubiquitination	QYKVHLDLWVKSLSP HHHHHHHHHHHCCCH	7.73	24816145
635	Acetylation	VHLDLWVKSLSPQDR HHHHHHHHCCCHHHH	33.81	26051181
636	Phosphorylation	HLDLWVKSLSPQDRA HHHHHHHCCCHHHHH	25.18	24732914
638	Phosphorylation	DLWVKSLSPQDRAAY HHHHHCCCHHHHHHH	27.83	25159151
638	Ubiquitination	DLWVKSLSPQDRAAY HHHHHCCCHHHHHHH	27.83	24816145
642	Methylation	KSLSPQDRAAYKEYI HCCCHHHHHHHHHHH	18.83	115919405
646	Acetylation	PQDRAAYKEYISNKR HHHHHHHHHHHHHHH	39.04	26051181
646	Ubiquitination	PQDRAAYKEYISNKR HHHHHHHHHHHHHHH	39.04	29967540
648	Phosphorylation	DRAAYKEYISNKRKS HHHHHHHHHHHHHHH	12.90	-
652	2-Hydroxyisobutyrylation	YKEYISNKRKSMTKL HHHHHHHHHHHCHHC	55.18	-
652	Acetylation	YKEYISNKRKSMTKL HHHHHHHHHHHCHHC	55.18	25953088
652	Ubiquitination	YKEYISNKRKSMTKL HHHHHHHHHHHCHHC	55.18	24816145
655	Phosphorylation	YISNKRKSMTKLRGP HHHHHHHHCHHCCCC	35.40	29449344
657	Phosphorylation	SNKRKSMTKLRGPNP HHHHHHCHHCCCCCC	33.74	29449344
658	Ubiquitination	NKRKSMTKLRGPNPK HHHHHCHHCCCCCCC	27.78	24816145
666	Phosphorylation	LRGPNPKSSRTTLQS CCCCCCCCCCCCCCC	26.72	19651622
669	Ubiquitination	PNPKSSRTTLQSKSE CCCCCCCCCCCCCCC	33.53	24816145
675	Ubiquitination	RTTLQSKSESEEDDE CCCCCCCCCCCCCCC	52.15	24816145

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
117	T	Phosphorylation	Kinase	MAPK1	P28482	GPS
117	T	Phosphorylation	Kinase	MAPK3	P27361	GPS
201	T	Phosphorylation	Kinase	MAPK1	P28482	GPS
201	T	Phosphorylation	Kinase	MAPK3	P27361	GPS
389	S	Phosphorylation	Kinase	CDK2	P24941	PhosphoELM
412	S	Phosphorylation	Kinase	PKCI	P41743	PSP
484	S	Phosphorylation	Kinase	CDK4	P11802	PhosphoELM

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UBF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UBF1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TBP_HUMAN	TBP	physical	8552083
TAF1C_HUMAN	TAF1C	physical	11698641
RPA34_HUMAN	CD3EAP	physical	9426281
RB_HUMAN	RB1	physical	11042686
ACTN4_HUMAN	ACTN4	physical	20197409
TLE1_HUMAN	TLE1	physical	20160071
IRS1_HUMAN	IRS1	physical	17332342
PK3CA_HUMAN	PIK3CA	physical	17332342
SIR7_HUMAN	SIRT7	physical	22147730
RPA1_HUMAN	POLR1A	physical	22147730
MBB1A_HUMAN	MYBBP1A	physical	22147730
SMCA5_HUMAN	SMARCA5	physical	22147730
SIR7_HUMAN	SIRT7	physical	22586326
HDAC1_HUMAN	HDAC1	physical	22393235
RUNX2_HUMAN	RUNX2	physical	22393235
RB_HUMAN	RB1	physical	7877691
WDR70_HUMAN	WDR70	physical	22939629
YETS4_HUMAN	YEATS4	physical	22939629
KAT2B_HUMAN	KAT2B	physical	23667505
AP3M1_HUMAN	AP3M1	physical	26344197
RTF1_HUMAN	RTF1	physical	26344197

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UBF1_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-484, AND MASS SPECTROMETRY.	19413330 [Abstract]
Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-484, AND MASS SPECTROMETRY.	19413330 [Abstract]
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