RHG21_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RHG21_HUMAN
• UniProt AC: Q5T5U3
• Protein Name: Rho GTPase-activating protein 21
• Gene Name: ARHGAP21
• Organism: Homo sapiens (Human).
• Sequence Length: 1957
• Subcellular Localization: Golgi apparatus membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
• Protein Description: Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions..
• Protein Sequence: MATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGFGFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MATRRTGLSEGDG --CCCCCCCCCCCCC	38.90	28102081
9	Phosphorylation	ATRRTGLSEGDGDKL CCCCCCCCCCCCCCC	40.66	25106551
10	Phosphorylation	TRRTGLSEGDGDKLK CCCCCCCCCCCCCCE	67.36	-
25	Acetylation	ACEVSKNKDGKEQSE EEEEECCCCCCCCCC	72.15	20167786
26	Acetylation	CEVSKNKDGKEQSET EEEECCCCCCCCCCE	80.79	-
28	Acetylation	VSKNKDGKEQSETVS EECCCCCCCCCCEEE	63.81	20167786
29	Acetylation	SKNKDGKEQSETVSL ECCCCCCCCCCEEEC	65.94	-
31	Phosphorylation	NKDGKEQSETVSLSE CCCCCCCCCEEECCC	36.00	27251275
33	Phosphorylation	DGKEQSETVSLSEDE CCCCCCCEEECCCCC	22.20	30576142
35	Phosphorylation	KEQSETVSLSEDETF CCCCCEEECCCCCCC	33.33	30624053
36	Phosphorylation	EQSETVSLSEDETFS CCCCEEECCCCCCCC	5.89	-
37	Phosphorylation	QSETVSLSEDETFSW CCCEEECCCCCCCCC	35.18	27251275
38	Phosphorylation	SETVSLSEDETFSWP CCEEECCCCCCCCCC	66.22	27251275
41	Phosphorylation	VSLSEDETFSWPGPK EECCCCCCCCCCCCE	34.98	32142685
48	Acetylation	TFSWPGPKTVTLKRT CCCCCCCEEEEEEEE	62.64	20167786
49	Acetylation	FSWPGPKTVTLKRTS CCCCCCEEEEEEEEC	23.12	-
55	Phosphorylation	KTVTLKRTSQGFGFT EEEEEEEECCCCCEE	24.66	20068231
56	Phosphorylation	TVTLKRTSQGFGFTL EEEEEEECCCCCEEE	32.13	22617229
57	Phosphorylation	VTLKRTSQGFGFTLR EEEEEECCCCCEEEE	51.09	24719451
62	Phosphorylation	TSQGFGFTLRHFIVY ECCCCCEEEEEEEEE	24.22	24719451
97	Phosphorylation	KQRNRLEPMDTIFVK CCCCCCCCCCEEEEE	30.46	32142685
104	Phosphorylation	PMDTIFVKQVKEGGP CCCEEEEEEHHCCCC	38.33	32142685
130	Phosphorylation	IIKVNGESVIGKTYS EEEECCEECCCCCHH	22.04	24719451
131	Phosphorylation	IKVNGESVIGKTYSQ EEECCEECCCCCHHH	6.10	24719451
156	Phosphorylation	TLELSVMPKDEDILQ EEEEEECCCCHHHHH	38.50	32142685
160	Phosphorylation	SVMPKDEDILQVLQF EECCCCHHHHHHHHH	57.96	32142685
188	Phosphorylation	YLKGNEAYSGNARNI HHCCCCCCCCCCCCC	15.78	20860994
219	Phosphorylation	AMAQPVEISPPDSSL CCCCCCEECCCCCCC	8.35	32142685
220	Phosphorylation	MAQPVEISPPDSSLS CCCCCEECCCCCCCC	19.51	28348404
231	Phosphorylation	SSLSKQQTSTPVLTQ CCCCCCCCCCCCCCC	31.88	22167270
232	Phosphorylation	SLSKQQTSTPVLTQP CCCCCCCCCCCCCCC	26.78	22167270
233	Phosphorylation	LSKQQTSTPVLTQPG CCCCCCCCCCCCCCC	22.32	22167270
234	Phosphorylation	SKQQTSTPVLTQPGR CCCCCCCCCCCCCCC	20.91	24719451
237	Phosphorylation	QTSTPVLTQPGRAYR CCCCCCCCCCCCEEE	32.71	28985074
243	Phosphorylation	LTQPGRAYRMEIQVP CCCCCCEEEEEEECC	14.77	21712546
244	Phosphorylation	TQPGRAYRMEIQVPP CCCCCEEEEEEECCC	18.44	32142685
252	Phosphorylation	MEIQVPPSPTDVAKS EEEECCCCCCCCCCC	34.07	30266825
253	Phosphorylation	EIQVPPSPTDVAKSN EEECCCCCCCCCCCC	38.09	24719451
254	Phosphorylation	IQVPPSPTDVAKSNT EECCCCCCCCCCCCC	47.66	30266825
255	Phosphorylation	QVPPSPTDVAKSNTA ECCCCCCCCCCCCCE	41.58	-
263	Phosphorylation	VAKSNTAVCVCNESV CCCCCCEEEECCCCC	2.06	32142685
269	Phosphorylation	AVCVCNESVRTVIVP EEEECCCCCCEEEEC	11.69	28555341
272	Phosphorylation	VCNESVRTVIVPSEK ECCCCCCEEEECCHH	16.66	28985074
285	Phosphorylation	EKVVDLLSNRNNHTG HHHHHHHHCCCCCCC	40.83	20068231
286	Phosphorylation	KVVDLLSNRNNHTGP HHHHHHHCCCCCCCC	51.15	20068231
297	Phosphorylation	HTGPSHRTEEVRYGV CCCCCCCCCCHHCCC	30.95	29083192
302	Phosphorylation	HRTEEVRYGVSEQTS CCCCCHHCCCCCCCC	27.36	27251275
305	Phosphorylation	EEVRYGVSEQTSLKT CCHHCCCCCCCCCEE	21.44	29083192
307	Phosphorylation	VRYGVSEQTSLKTVS HHCCCCCCCCCEEEC	28.96	32142685
308	Phosphorylation	RYGVSEQTSLKTVSR HCCCCCCCCCEEECC	31.79	27251275
309	Phosphorylation	YGVSEQTSLKTVSRT CCCCCCCCCEEECCC	27.80	28555341
310	Phosphorylation	GVSEQTSLKTVSRTT CCCCCCCCEEECCCC	6.47	27251275
316	Phosphorylation	SLKTVSRTTSPPLSI CCEEECCCCCCCCCC	24.91	22167270
317	Phosphorylation	LKTVSRTTSPPLSIP CEEECCCCCCCCCCC	37.82	22167270
318	Phosphorylation	KTVSRTTSPPLSIPT EEECCCCCCCCCCCC	24.73	22167270
319	Phosphorylation	TVSRTTSPPLSIPTT EECCCCCCCCCCCCC	31.59	24719451
322	Phosphorylation	RTTSPPLSIPTTHLI CCCCCCCCCCCCCEE	32.09	22167270
325	Phosphorylation	SPPLSIPTTHLIHQP CCCCCCCCCCEECCC	25.77	23403867
326	Phosphorylation	PPLSIPTTHLIHQPA CCCCCCCCCEECCCC	14.88	23403867
335	Phosphorylation	LIHQPAGSRSLEPSG EECCCCCCCCCCCCE	22.32	23403867
337	Phosphorylation	HQPAGSRSLEPSGIL CCCCCCCCCCCCEEE	38.49	25850435
338	Phosphorylation	QPAGSRSLEPSGILL CCCCCCCCCCCEEEE	12.48	-
346	Methylation	EPSGILLKSGNYSGH CCCEEEEECCCCCCC	53.52	-
347	Methylation	PSGILLKSGNYSGHS CCEEEEECCCCCCCC	32.04	-
347	Ubiquitination	PSGILLKSGNYSGHS CCEEEEECCCCCCCC	32.04	29967540
350	Phosphorylation	ILLKSGNYSGHSDGI EEEECCCCCCCCCCC	21.39	22817900
351	Phosphorylation	LLKSGNYSGHSDGIS EEECCCCCCCCCCCC	33.75	-
358	Phosphorylation	SGHSDGISSSRSQAV CCCCCCCCCCHHHCE	27.99	24905233
359	Phosphorylation	GHSDGISSSRSQAVE CCCCCCCCCHHHCEE	28.05	24905233
360	Phosphorylation	HSDGISSSRSQAVEA CCCCCCCCHHHCEEC	29.21	24905233
369	Phosphorylation	SQAVEAPSVSVNHYS HHCEECCCEEECCCC	33.79	20068231
371	Phosphorylation	AVEAPSVSVNHYSPN CEECCCEEECCCCCC	22.87	25159151
375	Phosphorylation	PSVSVNHYSPNSHQH CCEEECCCCCCCCCC	22.18	27174698
376	Phosphorylation	SVSVNHYSPNSHQHI CEEECCCCCCCCCCC	15.28	25159151
377	Phosphorylation	VSVNHYSPNSHQHID EEECCCCCCCCCCCC	38.89	24719451
378	Phosphorylation	SVNHYSPNSHQHIDW EECCCCCCCCCCCCC	46.30	32142685
379	Phosphorylation	VNHYSPNSHQHIDWK ECCCCCCCCCCCCCC	28.10	20068231
380	Phosphorylation	NHYSPNSHQHIDWKN CCCCCCCCCCCCCCC	29.85	20068231
391	Phosphorylation	DWKNYKTYKEYIDNR CCCCCCCHHHHHHHC	9.55	-
394	Phosphorylation	NYKTYKEYIDNRRLH CCCCHHHHHHHCCEE	14.93	25394399
402	Phosphorylation	IDNRRLHIGCRTIQE HHHCCEECCCCHHHH	7.06	32142685
413	Phosphorylation	TIQERLDSLRAASQS HHHHHHHHHHHHHCC	25.09	28555341
418	Phosphorylation	LDSLRAASQSTTDYN HHHHHHHHCCCCCHH	24.55	28555341
420	Phosphorylation	SLRAASQSTTDYNQV HHHHHHCCCCCHHHC	30.68	28555341
421	Phosphorylation	LRAASQSTTDYNQVV HHHHHCCCCCHHHCC	18.95	28555341
422	Phosphorylation	RAASQSTTDYNQVVP HHHHCCCCCHHHCCC	41.56	-
424	Phosphorylation	ASQSTTDYNQVVPNR HHCCCCCHHHCCCCC	12.85	27259358
425	Phosphorylation	SQSTTDYNQVVPNRT HCCCCCHHHCCCCCC	30.86	-
440	Phosphorylation	TLQGRRRSTSHDRVP CCCCCCCCCCCCCCC	32.24	27273156
441	Phosphorylation	LQGRRRSTSHDRVPQ CCCCCCCCCCCCCCC	28.41	23927012
442	Phosphorylation	QGRRRSTSHDRVPQS CCCCCCCCCCCCCCH	25.33	23401153
443	Phosphorylation	GRRRSTSHDRVPQSV CCCCCCCCCCCCCHH	27.30	24719451
449	Phosphorylation	SHDRVPQSVQIRQRS CCCCCCCHHHHHHCC	15.21	23403867
456	Phosphorylation	SVQIRQRSVSQERLE HHHHHHCCCCHHHHC	20.13	23927012
457	Phosphorylation	VQIRQRSVSQERLED HHHHHCCCCHHHHCH	8.14	27251275
458	Phosphorylation	QIRQRSVSQERLEDS HHHHCCCCHHHHCHH	27.80	27273156
459	Phosphorylation	IRQRSVSQERLEDSV HHHCCCCHHHHCHHH	37.36	24719451
465	Phosphorylation	SQERLEDSVLMKYCP CHHHHCHHHHHHHCC	14.05	23403867
466	Phosphorylation	QERLEDSVLMKYCPR HHHHCHHHHHHHCCC	10.54	32142685
470	Phosphorylation	EDSVLMKYCPRSASQ CHHHHHHHCCCCCCC	8.17	32142685
474	Phosphorylation	LMKYCPRSASQGALT HHHHCCCCCCCCCCC	19.88	23927012
475	O-linked_Glycosylation	MKYCPRSASQGALTS HHHCCCCCCCCCCCC	13.73	30379171
475	Phosphorylation	MKYCPRSASQGALTS HHHCCCCCCCCCCCC	13.73	18220336
476	Phosphorylation	KYCPRSASQGALTSP HHCCCCCCCCCCCCC	30.32	23927012
477	Phosphorylation	YCPRSASQGALTSPS HCCCCCCCCCCCCCC	40.68	24719451
481	Phosphorylation	SASQGALTSPSVSFS CCCCCCCCCCCEECC	37.75	23927012
482	Phosphorylation	ASQGALTSPSVSFSN CCCCCCCCCCEECCC	18.94	23927012
483	Phosphorylation	SQGALTSPSVSFSNH CCCCCCCCCEECCCC	33.25	18669648
484	Phosphorylation	QGALTSPSVSFSNHR CCCCCCCCEECCCCC	30.11	23927012
486	Phosphorylation	ALTSPSVSFSNHRTR CCCCCCEECCCCCCC	27.56	23403867
487	Phosphorylation	LTSPSVSFSNHRTRS CCCCCEECCCCCCCC	8.75	-
488	Phosphorylation	TSPSVSFSNHRTRSW CCCCEECCCCCCCCC	24.99	23403867
492	Phosphorylation	VSFSNHRTRSWDYIE EECCCCCCCCCEEEC	22.85	22199227
493	Phosphorylation	SFSNHRTRSWDYIEG ECCCCCCCCCEEECC	35.39	24719451
494	Phosphorylation	FSNHRTRSWDYIEGQ CCCCCCCCCEEECCC	24.56	22199227
495	Phosphorylation	SNHRTRSWDYIEGQD CCCCCCCCEEECCCC	10.11	27251275
497	Phosphorylation	HRTRSWDYIEGQDET CCCCCCEEECCCCCC	8.46	22199227
504	Phosphorylation	YIEGQDETLENVNSG EECCCCCCCCCCCCC	47.89	27251275
510	Phosphorylation	ETLENVNSGTPIPDS CCCCCCCCCCCCCCC	39.50	25332170
512	Phosphorylation	LENVNSGTPIPDSNG CCCCCCCCCCCCCCC	20.19	25332170
517	Phosphorylation	SGTPIPDSNGEKKQT CCCCCCCCCCCCCEE	41.18	32142685
526	Phosphorylation	GEKKQTYKWSGFTEQ CCCCEEEECCCCCCC	37.97	32142685
551	Phosphorylation	RQQEIHKSFRGSNFT HHHHHHHHHCCCCCE	13.15	24719451
552	Phosphorylation	QQEIHKSFRGSNFTV HHHHHHHHCCCCCEE	14.13	24719451
553	Methylation	QEIHKSFRGSNFTVA HHHHHHHCCCCCEEC	55.51	24129315
554	Methylation	EIHKSFRGSNFTVAP HHHHHHCCCCCEECC	25.57	24129315
555	Phosphorylation	IHKSFRGSNFTVAPS HHHHHCCCCCEECCE	25.23	28555341
562	Phosphorylation	SNFTVAPSVVNSDNR CCCEECCEEECCCCC	29.03	-
566	Phosphorylation	VAPSVVNSDNRRMSG ECCEEECCCCCCCCC	25.34	23882029
572	Phosphorylation	NSDNRRMSGRGVGSV CCCCCCCCCCCCCCH	24.43	23882029
574	Methylation	DNRRMSGRGVGSVSQ CCCCCCCCCCCCHHH	29.35	24129315
575	Methylation	NRRMSGRGVGSVSQF CCCCCCCCCCCHHHH	31.50	24129315
578	Phosphorylation	MSGRGVGSVSQFKKI CCCCCCCCHHHHCCC	19.05	23882029
580	Phosphorylation	GRGVGSVSQFKKIPP CCCCCCHHHHCCCCC	31.43	23882029
585	Phosphorylation	SVSQFKKIPPDLKTL CHHHHCCCCCCHHHH	6.54	32142685
600	Phosphorylation	QSNRNFQTTCGMSLP HCCCCCCCCCCCCCC	21.66	27251275
601	Phosphorylation	SNRNFQTTCGMSLPR CCCCCCCCCCCCCCC	9.04	24719451
602	Phosphorylation	NRNFQTTCGMSLPRG CCCCCCCCCCCCCCC	4.97	24719451
605	Phosphorylation	FQTTCGMSLPRGISQ CCCCCCCCCCCCCCC	22.09	25106551
606	Phosphorylation	QTTCGMSLPRGISQD CCCCCCCCCCCCCCC	2.20	-
608	Methylation	TCGMSLPRGISQDRS CCCCCCCCCCCCCCC	61.44	-
609	Methylation	CGMSLPRGISQDRSP CCCCCCCCCCCCCCC	23.20	-
611	Phosphorylation	MSLPRGISQDRSPLV CCCCCCCCCCCCCCE	28.93	30266825
612	Phosphorylation	SLPRGISQDRSPLVK CCCCCCCCCCCCCEE	48.49	24719451
615	Phosphorylation	RGISQDRSPLVKVRS CCCCCCCCCCEEECC	30.76	23401153
616	Phosphorylation	GISQDRSPLVKVRSN CCCCCCCCCEEECCC	41.91	19691289
622	Phosphorylation	SPLVKVRSNSLKAPS CCCEEECCCCCCCCC	33.48	30266825
623	Phosphorylation	PLVKVRSNSLKAPST CCEEECCCCCCCCCC	40.57	24719451
624	Phosphorylation	LVKVRSNSLKAPSTH CEEECCCCCCCCCCC	32.28	30266825
625	Phosphorylation	VKVRSNSLKAPSTHV EEECCCCCCCCCCCC	6.84	23186163
626	Acetylation	KVRSNSLKAPSTHVT EECCCCCCCCCCCCC	59.06	7408205
629	Phosphorylation	SNSLKAPSTHVTKPS CCCCCCCCCCCCCCC	35.68	30266825
630	Phosphorylation	NSLKAPSTHVTKPSF CCCCCCCCCCCCCCC	21.21	30266825
633	Phosphorylation	KAPSTHVTKPSFSQK CCCCCCCCCCCCCCC	29.63	23927012
636	Phosphorylation	STHVTKPSFSQKSFV CCCCCCCCCCCCCCE	38.80	23927012
638	Phosphorylation	HVTKPSFSQKSFVSI CCCCCCCCCCCCEEC	40.82	23927012
658	Phosphorylation	VNHLHQNSLLNQQTW CCCHHHCCCCCCCCE	27.88	27251275
659	Phosphorylation	NHLHQNSLLNQQTWV CCHHHCCCCCCCCEE	7.35	27251275
667	Phosphorylation	LNQQTWVRTDSAPDQ CCCCCEEECCCCCHH	25.11	32142685
668	Phosphorylation	NQQTWVRTDSAPDQQ CCCCEEECCCCCHHH	25.37	23186163
670	Phosphorylation	QTWVRTDSAPDQQVE CCEEECCCCCHHHCC	40.88	23312004
671	Phosphorylation	TWVRTDSAPDQQVET CEEECCCCCHHHCCC	17.94	27251275
673	Phosphorylation	VRTDSAPDQQVETGK EECCCCCHHHCCCCC	51.79	32142685
678	Phosphorylation	APDQQVETGKSPSLS CCHHHCCCCCCCCCC	51.56	22199227
681	Phosphorylation	QQVETGKSPSLSGAS HHCCCCCCCCCCCCC	22.52	30576142
681	Ubiquitination	QQVETGKSPSLSGAS HHCCCCCCCCCCCCC	22.52	29967540
682	Phosphorylation	QVETGKSPSLSGASA HCCCCCCCCCCCCCC	42.66	27251275
683	Phosphorylation	VETGKSPSLSGASAK CCCCCCCCCCCCCCC	42.11	26657352
684	Phosphorylation	ETGKSPSLSGASAKP CCCCCCCCCCCCCCC	6.59	27251275
685	Phosphorylation	TGKSPSLSGASAKPA CCCCCCCCCCCCCCC	36.33	22199227
688	Phosphorylation	SPSLSGASAKPAPQS CCCCCCCCCCCCCCC	40.11	22199227
695	Phosphorylation	SAKPAPQSSENAGTS CCCCCCCCCCCCCCC	38.26	23186163
696	Phosphorylation	AKPAPQSSENAGTSD CCCCCCCCCCCCCCC	29.62	23186163
701	Phosphorylation	QSSENAGTSDLELPV CCCCCCCCCCCCCCH	19.36	23186163
702	Phosphorylation	SSENAGTSDLELPVS CCCCCCCCCCCCCHH	39.00	23186163
710	Phosphorylation	DLELPVSQRNQDLSL CCCCCHHHHHHCCCH	48.88	32142685
716	Phosphorylation	SQRNQDLSLQEAETE HHHHHCCCHHHHHHH	35.97	20068231
717	Phosphorylation	QRNQDLSLQEAETEQ HHHHCCCHHHHHHHC	7.49	20068231
723	Phosphorylation	SLQEAETEQSDTLDN CHHHHHHHCCCCCCC	39.32	32142685
725	Phosphorylation	QEAETEQSDTLDNKE HHHHHHCCCCCCCCE	26.74	29083192
727	Phosphorylation	AETEQSDTLDNKEAV HHHHCCCCCCCCEEE	41.06	29083192
741	Phosphorylation	VILREKPPSGRQTPQ EEEECCCCCCCCCCC	61.56	32645325
742	Phosphorylation	ILREKPPSGRQTPQP EEECCCCCCCCCCCC	55.95	30266825
743	Phosphorylation	LREKPPSGRQTPQPL EECCCCCCCCCCCCC	31.33	24719451
746	Phosphorylation	KPPSGRQTPQPLRHQ CCCCCCCCCCCCCCC	23.64	30266825
747	Phosphorylation	PPSGRQTPQPLRHQS CCCCCCCCCCCCCCC	26.00	24719451
754	Phosphorylation	PQPLRHQSYILAVND CCCCCCCCEEEEEEC	14.17	28857561
755	Phosphorylation	QPLRHQSYILAVNDQ CCCCCCCEEEEEECC	8.06	24719451
766	Phosphorylation	VNDQETGSDTTCWLP EECCCCCCCCEEECC	38.92	32142685
782	Phosphorylation	DARREVHIKRMEERK HHHCHHHHHHHHHHH	3.51	32142685
797	Phosphorylation	ASSTSPPGDSLASIP CCCCCCCCCCCCCCC	40.29	32645325
825	Phosphorylation	IAHIPASAVISASTS CCCCCHHHHHCCCCC	12.55	32142685
856	Phosphorylation	PLIRRQLSHDHESVG HHHHHHHCCCCCCCC	20.66	23927012
857	Phosphorylation	LIRRQLSHDHESVGP HHHHHHCCCCCCCCC	49.38	17081983
861	Phosphorylation	QLSHDHESVGPPSLD HHCCCCCCCCCCCCC	29.02	30266825
862	Phosphorylation	LSHDHESVGPPSLDA HCCCCCCCCCCCCCC	14.03	17081983
866	Phosphorylation	HESVGPPSLDAQPNS CCCCCCCCCCCCCCC	41.85	23927012
867	Phosphorylation	ESVGPPSLDAQPNSK CCCCCCCCCCCCCCC	8.57	20068231
870	Phosphorylation	GPPSLDAQPNSKTER CCCCCCCCCCCCCHH	37.06	32142685
873	Phosphorylation	SLDAQPNSKTERSKS CCCCCCCCCCHHHHC	47.87	23927012
874	Phosphorylation	LDAQPNSKTERSKSY CCCCCCCCCHHHHCH	62.13	17081983
878	Phosphorylation	PNSKTERSKSYDEGL CCCCCHHHHCHHCCC	21.52	23927012
879	Phosphorylation	NSKTERSKSYDEGLD CCCCHHHHCHHCCCH	60.29	-
880	Phosphorylation	SKTERSKSYDEGLDD CCCHHHHCHHCCCHH	38.78	23401153
881	Phosphorylation	KTERSKSYDEGLDDY CCHHHHCHHCCCHHH	23.04	25463755
882	Phosphorylation	TERSKSYDEGLDDYR CHHHHCHHCCCHHHH	51.05	24275569
888	Phosphorylation	YDEGLDDYREDAKLS HHCCCHHHHHHHHHC	18.64	23403867
889	Phosphorylation	DEGLDDYREDAKLSF HCCCHHHHHHHHHCC	42.17	-
890 (in isoform 3)	Phosphorylation	-	56.97	21406692
895	Phosphorylation	YREDAKLSFKHVSSL HHHHHHHCCEEHHHC	31.38	23312004
896	Phosphorylation	REDAKLSFKHVSSLK HHHHHHCCEEHHHCC	10.32	24719451
897	Methylation	EDAKLSFKHVSSLKG HHHHHCCEEHHHCCC	39.46	-
898	Methylation	DAKLSFKHVSSLKGI HHHHCCEEHHHCCCC	23.76	-
900	Phosphorylation	KLSFKHVSSLKGIKI HHCCEEHHHCCCCEE	29.67	21406692
901	Phosphorylation	LSFKHVSSLKGIKIA HCCEEHHHCCCCEEC	32.77	24719451
902	Phosphorylation	SFKHVSSLKGIKIAD CCEEHHHCCCCEECC	4.60	24719451
904	Ubiquitination	KHVSSLKGIKIADSQ EEHHHCCCCEECCCC	31.54	29967540
910	Phosphorylation	KGIKIADSQKSSEDS CCCEECCCCCCCCCC	30.41	20860994
911	Phosphorylation	GIKIADSQKSSEDSG CCEECCCCCCCCCCC	50.64	-
913	Phosphorylation	KIADSQKSSEDSGSR EECCCCCCCCCCCCC	31.18	23403867
914	Phosphorylation	IADSQKSSEDSGSRK ECCCCCCCCCCCCCC	53.08	23403867
917	Phosphorylation	SQKSSEDSGSRKDSS CCCCCCCCCCCCCCC	34.32	23403867
918	Phosphorylation	QKSSEDSGSRKDSSS CCCCCCCCCCCCCCH	43.73	27251275
919	Phosphorylation	KSSEDSGSRKDSSSE CCCCCCCCCCCCCHH	39.86	23403867
923	Phosphorylation	DSGSRKDSSSEVFSD CCCCCCCCCHHHCHH	38.51	29255136
924	Phosphorylation	SGSRKDSSSEVFSDA CCCCCCCCHHHCHHH	40.42	23401153
925	Phosphorylation	GSRKDSSSEVFSDAA CCCCCCCHHHCHHHH	41.55	30266825
926	Phosphorylation	SRKDSSSEVFSDAAK CCCCCCHHHCHHHHH	49.91	27251275
929	Phosphorylation	DSSSEVFSDAAKEGW CCCHHHCHHHHHHCC	31.36	23403867
944	Phosphorylation	LHFRPLVTDKGKRVG EEEEEEECCCCCCCC	39.41	32645325
953	Phosphorylation	KGKRVGGSIRPWKQM CCCCCCCCCCCCCEE	14.97	30266825
954	Phosphorylation	GKRVGGSIRPWKQMY CCCCCCCCCCCCEEE	7.49	18212344
961	Phosphorylation	IRPWKQMYVVLRGHS CCCCCEEEEEECCCE	5.73	24043423
968	Phosphorylation	YVVLRGHSLYLYKDK EEEECCCEEEEEECC	22.87	24043423
970	Phosphorylation	VLRGHSLYLYKDKRE EECCCEEEEEECCCC	15.82	24043423
972	Phosphorylation	RGHSLYLYKDKREQT CCCEEEEEECCCCCC	12.00	24043423
979	Phosphorylation	YKDKREQTTPSEEEQ EECCCCCCCCCHHCC	35.60	22817900
980	Phosphorylation	KDKREQTTPSEEEQP ECCCCCCCCCHHCCC	25.22	-
982	Phosphorylation	KREQTTPSEEEQPIS CCCCCCCCHHCCCCE	56.39	22817900
983	Phosphorylation	REQTTPSEEEQPISV CCCCCCCHHCCCCEE	67.75	-
1058	Methylation	DLISRRIKEYNNLMS HHHHHHHHHHHHHHH	52.95	-
1059	Methylation	LISRRIKEYNNLMSK HHHHHHHHHHHHHHH	51.64	-
1060	Phosphorylation	ISRRIKEYNNLMSKA HHHHHHHHHHHHHHH	12.35	30576142
1073	Acetylation	KAEQLPKTPRQSLSI HHHHCCCCHHHHHHH	23.05	19413330
1073	Phosphorylation	KAEQLPKTPRQSLSI HHHHCCCCHHHHHHH	23.05	19413330
1074	Phosphorylation	AEQLPKTPRQSLSIR HHHCCCCHHHHHHHH	38.14	24719451
1077	Phosphorylation	LPKTPRQSLSIRQTL CCCCHHHHHHHHHHH	25.93	22210691
1078	Phosphorylation	PKTPRQSLSIRQTLL CCCHHHHHHHHHHHH	3.60	24719451
1079	Phosphorylation	KTPRQSLSIRQTLLG CCHHHHHHHHHHHHC	22.44	22210691
1080	Phosphorylation	TPRQSLSIRQTLLGA CHHHHHHHHHHHHCC	4.61	27251275
1083	Phosphorylation	QSLSIRQTLLGAKSE HHHHHHHHHHCCCCC	17.69	29396449
1089	Phosphorylation	QTLLGAKSEPKTQSP HHHHCCCCCCCCCCC	59.61	29396449
1090	Phosphorylation	TLLGAKSEPKTQSPH HHHCCCCCCCCCCCC	50.54	17081983
1093	Phosphorylation	GAKSEPKTQSPHSPK CCCCCCCCCCCCCCH	45.02	21406692
1095	Phosphorylation	KSEPKTQSPHSPKEE CCCCCCCCCCCCHHH	29.79	30576142
1096	Phosphorylation	SEPKTQSPHSPKEES CCCCCCCCCCCHHHH	23.35	-
1098	Phosphorylation	PKTQSPHSPKEESER CCCCCCCCCHHHHHH	40.84	26055452
1099	Phosphorylation	KTQSPHSPKEESERK CCCCCCCCHHHHHHH	45.07	24719451
1103	Phosphorylation	PHSPKEESERKLLSK CCCCHHHHHHHHCCC	43.74	30576142
1109	Phosphorylation	ESERKLLSKDDTSPP HHHHHHCCCCCCCCC	44.46	23403867
1113	Phosphorylation	KLLSKDDTSPPKDKG HHCCCCCCCCCCCCC	53.95	21712546
1114	Phosphorylation	LLSKDDTSPPKDKGT HCCCCCCCCCCCCCC	46.31	22617229
1115	Phosphorylation	LSKDDTSPPKDKGTW CCCCCCCCCCCCCCH	41.89	23186163
1128	Phosphorylation	TWRKGIPSIMRKTFE CHHCCCCHHHHHHHC	27.39	21712546
1129	Phosphorylation	WRKGIPSIMRKTFEK HHCCCCHHHHHHHCC	2.31	27251275
1133	Phosphorylation	IPSIMRKTFEKKPTA CCHHHHHHHCCCCCC	27.02	-
1139	Phosphorylation	KTFEKKPTATGTFGV HHHCCCCCCCCCCCE	45.81	-
1141	Phosphorylation	FEKKPTATGTFGVRL HCCCCCCCCCCCEEH	38.95	-
1143	Phosphorylation	KKPTATGTFGVRLDD CCCCCCCCCCEEHHC	16.92	-
1178	Phosphorylation	VEERGLEYTGIYRVP HHHHCCEEEEEEECC	18.47	27642862
1219	Phosphorylation	WRDLNVISSLLKSFF HHHHHHHHHHHHHHH	15.62	21406692
1220	Phosphorylation	RDLNVISSLLKSFFR HHHHHHHHHHHHHHH	26.96	33259812
1221	Phosphorylation	DLNVISSLLKSFFRK HHHHHHHHHHHHHHC	5.80	17081983
1224	Phosphorylation	VISSLLKSFFRKLPE HHHHHHHHHHHCCCC	29.59	24719451
1225	Phosphorylation	ISSLLKSFFRKLPEP HHHHHHHHHHCCCCC	7.02	24719451
1239	Phosphorylation	PLFTNDKYADFIEAN CCCCCHHHHHHHHHC	17.80	18669648
1239	Ubiquitination	PLFTNDKYADFIEAN CCCCCHHHHHHHHHC	17.80	29967540
1240	Phosphorylation	LFTNDKYADFIEANR CCCCHHHHHHHHHCC	15.81	18669648
1276	Phosphorylation	HYETLKFLSAHLKTV HHHHHHHHHHHHHHH	4.17	33259812
1282	Phosphorylation	FLSAHLKTVAENSEK HHHHHHHHHHHHHHH	31.17	17081983
1283	Phosphorylation	LSAHLKTVAENSEKN HHHHHHHHHHHHHHC	6.34	17081983
1335	Phosphorylation	ETLIQHHDWFFTEEG HHHHHHCCCCCCCCC	41.58	33259812
1374	Phosphorylation	LLTNIGRTGVSPGDV HHHHCCCCCCCCCCC	36.40	21815630
1375	Phosphorylation	LTNIGRTGVSPGDVS HHHCCCCCCCCCCCC	19.28	-
1377	Phosphorylation	NIGRTGVSPGDVSDS HCCCCCCCCCCCCCC	25.22	25159151
1378	Phosphorylation	IGRTGVSPGDVSDSA CCCCCCCCCCCCCCC	40.37	18669648
1382	Phosphorylation	GVSPGDVSDSATSDS CCCCCCCCCCCCCCC	30.50	25159151
1383	Phosphorylation	VSPGDVSDSATSDST CCCCCCCCCCCCCCC	41.98	19413330
1384	Phosphorylation	SPGDVSDSATSDSTK CCCCCCCCCCCCCCC	26.41	23403867
1386	Phosphorylation	GDVSDSATSDSTKSK CCCCCCCCCCCCCCC	36.70	23403867
1387	Phosphorylation	DVSDSATSDSTKSKG CCCCCCCCCCCCCCC	29.31	23403867
1389	Phosphorylation	SDSATSDSTKSKGSW CCCCCCCCCCCCCCC	37.19	24732914
1390	Phosphorylation	DSATSDSTKSKGSWG CCCCCCCCCCCCCCC	44.31	24732914
1392	Phosphorylation	ATSDSTKSKGSWGSG CCCCCCCCCCCCCCC	42.19	23312004
1392	Ubiquitination	ATSDSTKSKGSWGSG CCCCCCCCCCCCCCC	42.19	29967540
1395	Phosphorylation	DSTKSKGSWGSGKDQ CCCCCCCCCCCCCCH	31.81	21406692
1396	Phosphorylation	STKSKGSWGSGKDQY CCCCCCCCCCCCCHH	17.40	24719451
1398	Phosphorylation	KSKGSWGSGKDQYSR CCCCCCCCCCCHHHH	36.09	21406692
1403	Phosphorylation	WGSGKDQYSRELLVS CCCCCCHHHHHHHHH	21.59	30257219
1410	Phosphorylation	YSRELLVSSIFAAAS HHHHHHHHHHHHHHH	20.07	28857561
1411	Phosphorylation	SRELLVSSIFAAASR HHHHHHHHHHHHHHH	17.78	26434776
1412	Phosphorylation	RELLVSSIFAAASRK HHHHHHHHHHHHHHC	1.81	-
1417	Phosphorylation	SSIFAAASRKRKKPK HHHHHHHHHCCCCCC	33.34	27422710
1418	Phosphorylation	SIFAAASRKRKKPKE HHHHHHHHCCCCCCH	37.76	24719451
1423	Phosphorylation	ASRKRKKPKEKAQPS HHHCCCCCCHHCCCC	53.74	33259812
1430	Phosphorylation	PKEKAQPSSSEDELD CCHHCCCCCCHHHHH	34.12	26503892
1431	Phosphorylation	KEKAQPSSSEDELDN CHHCCCCCCHHHHHH	44.42	25159151
1432	Phosphorylation	EKAQPSSSEDELDNV HHCCCCCCHHHHHHH	54.10	19664994
1433	Phosphorylation	KAQPSSSEDELDNVF HCCCCCCHHHHHHHE	58.41	19664994
1442	Sumoylation	ELDNVFFKKENVEQC HHHHHEECHHCHHHH	47.95	-
1443	Sumoylation	LDNVFFKKENVEQCH HHHHEECHHCHHHHC	49.73	22922005
1457	Phosphorylation	HNDTKEESKKESETL CCCCHHHHHHHHHHH	50.55	30631047
1484	Phosphorylation	STRKDPSTTKDEKIS CCCCCCCCCHHHCCC	43.16	20860994
1485	Phosphorylation	TRKDPSTTKDEKISL CCCCCCCCHHHCCCC	40.61	20860994
1491	Phosphorylation	TTKDEKISLGKESTP CCHHHCCCCCCCCCC	41.98	21712546
1492	Phosphorylation	TKDEKISLGKESTPS CHHHCCCCCCCCCCC	15.01	-
1496	Phosphorylation	KISLGKESTPSEEPS CCCCCCCCCCCCCCC	49.45	30266825
1497	Phosphorylation	ISLGKESTPSEEPSP CCCCCCCCCCCCCCC	31.74	30266825
1499	Phosphorylation	LGKESTPSEEPSPPH CCCCCCCCCCCCCCC	55.47	30266825
1503	Phosphorylation	STPSEEPSPPHNSKH CCCCCCCCCCCCCCC	55.11	30266825
1504	Phosphorylation	TPSEEPSPPHNSKHN CCCCCCCCCCCCCCC	44.90	23186163
1508	Phosphorylation	EPSPPHNSKHNKSPT CCCCCCCCCCCCCCC	32.05	30266825
1509	Phosphorylation	PSPPHNSKHNKSPTL CCCCCCCCCCCCCCC	57.42	-
1512	Ubiquitination	PHNSKHNKSPTLSCR CCCCCCCCCCCCEEE	58.49	33845483
1513	Phosphorylation	HNSKHNKSPTLSCRF CCCCCCCCCCCEEEE	28.56	30266825
1514	Phosphorylation	NSKHNKSPTLSCRFA CCCCCCCCCCEEEEE	38.68	24719451
1515	Phosphorylation	SKHNKSPTLSCRFAI CCCCCCCCCEEEEEH	38.09	30266825
1516	Phosphorylation	KHNKSPTLSCRFAIL CCCCCCCCEEEEEHH	5.30	24275569
1517	Phosphorylation	HNKSPTLSCRFAILK CCCCCCCEEEEEHHH	13.01	30266825
1518	Phosphorylation	NKSPTLSCRFAILKE CCCCCCEEEEEHHHH	4.70	-
1526	Phosphorylation	RFAILKESPRSLLAQ EEEHHHHCHHHHHHH	24.83	22167270
1527	Phosphorylation	FAILKESPRSLLAQK EEHHHHCHHHHHHHH	30.85	20068231
1528	Phosphorylation	AILKESPRSLLAQKS EHHHHCHHHHHHHHH	49.57	32142685
1529	Phosphorylation	ILKESPRSLLAQKSS HHHHCHHHHHHHHHH	30.99	21712546
1530	Phosphorylation	LKESPRSLLAQKSSH HHHCHHHHHHHHHHC	4.92	-
1535	Phosphorylation	RSLLAQKSSHLEETG HHHHHHHHHCHHHCC	15.77	28348404
1536	Phosphorylation	SLLAQKSSHLEETGS HHHHHHHHCHHHCCC	38.84	28348404
1550	Phosphorylation	SDSGTLLSTSSQASL CCCCCEEECCCHHHH	29.38	27251275
1551	Phosphorylation	DSGTLLSTSSQASLA CCCCEEECCCHHHHH	32.16	27251275
1552	Phosphorylation	SGTLLSTSSQASLAR CCCEEECCCHHHHHH	19.65	27251275
1553	Phosphorylation	GTLLSTSSQASLARF CCEEECCCHHHHHHH	29.83	27251275
1554	Phosphorylation	TLLSTSSQASLARFS CEEECCCHHHHHHHH	34.44	27251275
1561	Phosphorylation	QASLARFSMKKSTSP HHHHHHHHCCCCCCC	24.92	24719451
1562	Phosphorylation	ASLARFSMKKSTSPE HHHHHHHCCCCCCCC	6.11	24719451
1565	Phosphorylation	ARFSMKKSTSPETKH HHHHCCCCCCCCCHH	28.71	26699800
1566	Phosphorylation	RFSMKKSTSPETKHS HHHCCCCCCCCCHHH	58.12	26699800
1567	Phosphorylation	FSMKKSTSPETKHSE HHCCCCCCCCCHHHH	28.03	26699800
1568	Ubiquitination	SMKKSTSPETKHSEF HCCCCCCCCCHHHHH	54.05	33845483
1584	Phosphorylation	ANVSTITSDYSTTSS HCCHHHCCCCCCCCC	30.60	32142685
1594	Phosphorylation	STTSSATYLTSLDSS CCCCCCEEEEECCHH	14.01	27642862
1604	Phosphorylation	SLDSSRLSPEVQSVA ECCHHCCCHHHHHHH	20.22	19664994
1605	Phosphorylation	LDSSRLSPEVQSVAE CCHHCCCHHHHHHHH	50.82	19664994
1609	Phosphorylation	RLSPEVQSVAESKGD CCCHHHHHHHHHCCC	28.59	28060719
1613	Phosphorylation	EVQSVAESKGDEADD HHHHHHHHCCCCCCH	32.00	29116813
1623	Phosphorylation	DEADDERSELISEGR CCCCHHHHHHHHCCC	34.41	23663014
1627	Phosphorylation	DERSELISEGRPVET HHHHHHHHCCCCCCC	46.77	23663014
1627	Ubiquitination	DERSELISEGRPVET HHHHHHHHCCCCCCC	46.77	33845483
1634	Phosphorylation	SEGRPVETDSESEFP HCCCCCCCCCCCCCC	45.09	21712546
1635	Phosphorylation	EGRPVETDSESEFPV CCCCCCCCCCCCCCC	36.58	24719451
1636	Phosphorylation	GRPVETDSESEFPVF CCCCCCCCCCCCCCC	50.90	21712546
1637	Phosphorylation	RPVETDSESEFPVFP CCCCCCCCCCCCCCC	58.03	24719451
1638	Phosphorylation	PVETDSESEFPVFPT CCCCCCCCCCCCCCC	48.79	28102081
1639	Phosphorylation	VETDSESEFPVFPTA CCCCCCCCCCCCCCC	50.33	17081983
1643	Phosphorylation	SESEFPVFPTALTSE CCCCCCCCCCCCCCH	4.53	32142685
1645	Phosphorylation	SEFPVFPTALTSERL CCCCCCCCCCCCHHH	23.88	28102081
1661	Phosphorylation	RGKLQEVTKSSRRNS HHHHHHHHHHCCCCC	25.18	28348404
1663	Phosphorylation	KLQEVTKSSRRNSEG HHHHHHHHCCCCCCC	21.51	28348404
1664	Phosphorylation	LQEVTKSSRRNSEGS HHHHHHHCCCCCCCC	36.49	28348404
1668	Phosphorylation	TKSSRRNSEGSELSC HHHCCCCCCCCCCCC	41.33	29255136
1669	Phosphorylation	KSSRRNSEGSELSCT HHCCCCCCCCCCCCC	71.00	24719451
1671	Phosphorylation	SRRNSEGSELSCTEG CCCCCCCCCCCCCCC	31.17	30266825
1672	Phosphorylation	RRNSEGSELSCTEGS CCCCCCCCCCCCCCC	56.40	18669648
1674	Phosphorylation	NSEGSELSCTEGSLT CCCCCCCCCCCCCCC	18.23	30278072
1675	Phosphorylation	SEGSELSCTEGSLTS CCCCCCCCCCCCCCC	6.67	-
1676	Phosphorylation	EGSELSCTEGSLTSS CCCCCCCCCCCCCCC	39.75	23927012
1679	Phosphorylation	ELSCTEGSLTSSLDS CCCCCCCCCCCCHHH	23.42	23403867
1680	Phosphorylation	LSCTEGSLTSSLDSR CCCCCCCCCCCHHHH	8.72	-
1681	Phosphorylation	SCTEGSLTSSLDSRR CCCCCCCCCCHHHHH	20.26	23403867
1682	Phosphorylation	CTEGSLTSSLDSRRQ CCCCCCCCCHHHHHH	33.91	23403867
1683	Phosphorylation	TEGSLTSSLDSRRQL CCCCCCCCHHHHHHH	30.84	23403867
1684	Phosphorylation	EGSLTSSLDSRRQLF CCCCCCCHHHHHHHH	7.50	-
1686	Phosphorylation	SLTSSLDSRRQLFSS CCCCCHHHHHHHHHH	34.36	23403867
1692	Phosphorylation	DSRRQLFSSHKLIEC HHHHHHHHHCCEEEC	39.87	24719451
1693	Phosphorylation	SRRQLFSSHKLIECD HHHHHHHHCCEEECC	19.80	24719451
1694	Phosphorylation	RRQLFSSHKLIECDT HHHHHHHCCEEECCC	27.95	27251275
1701	Phosphorylation	HKLIECDTLSRKKSA CCEEECCCCCCCCCC	37.99	29255136
1702	Phosphorylation	KLIECDTLSRKKSAR CEEECCCCCCCCCCC	2.73	-
1703	Phosphorylation	LIECDTLSRKKSARF EEECCCCCCCCCCCC	44.11	30001349
1707	Phosphorylation	DTLSRKKSARFKSDS CCCCCCCCCCCCCCC	27.93	-
1712	Phosphorylation	KKSARFKSDSGSLGD CCCCCCCCCCCCCCC	34.01	29255136
1713	Phosphorylation	KSARFKSDSGSLGDA CCCCCCCCCCCCCCC	58.57	24719451
1714	Phosphorylation	SARFKSDSGSLGDAK CCCCCCCCCCCCCCC	37.05	29255136
1715	Ubiquitination	ARFKSDSGSLGDAKN CCCCCCCCCCCCCCC	31.70	33845483
1716	Phosphorylation	RFKSDSGSLGDAKNE CCCCCCCCCCCCCCC	32.88	23403867
1717	Phosphorylation	FKSDSGSLGDAKNEK CCCCCCCCCCCCCCC	9.09	27251275
1725	Ubiquitination	GDAKNEKEAPSLTKV CCCCCCCCCCCHHHH	60.68	33845483
1731	Phosphorylation	KEAPSLTKVFDVMKK CCCCCHHHHHHHHHC	46.31	32142685
1741	Phosphorylation	DVMKKGKSTGSLLTP HHHHCCCCCCCCCCC	46.82	29255136
1742	Phosphorylation	VMKKGKSTGSLLTPT HHHCCCCCCCCCCCC	33.99	29255136
1743	Phosphorylation	MKKGKSTGSLLTPTR HHCCCCCCCCCCCCC	24.32	20068231
1744	Phosphorylation	KKGKSTGSLLTPTRG HCCCCCCCCCCCCCC	21.94	23927012
1745	Phosphorylation	KGKSTGSLLTPTRGE CCCCCCCCCCCCCCC	6.98	-
1747	Phosphorylation	KSTGSLLTPTRGESE CCCCCCCCCCCCCCC	28.10	25159151
1748	Phosphorylation	STGSLLTPTRGESEK CCCCCCCCCCCCCCC	21.77	-
1749	Phosphorylation	TGSLLTPTRGESEKQ CCCCCCCCCCCCCCC	46.18	22199227
1750	Phosphorylation	GSLLTPTRGESEKQE CCCCCCCCCCCCCCC	48.35	20068231
1753	Phosphorylation	LTPTRGESEKQEPTW CCCCCCCCCCCCCCC	53.57	22199227
1761	Methylation	EKQEPTWKTKIADRL CCCCCCCCCHHHHHH	42.28	-
1762	Methylation	KQEPTWKTKIADRLK CCCCCCCCHHHHHHC	21.17	-
1763	Methylation	QEPTWKTKIADRLKL CCCCCCCHHHHHHCC	31.97	-
1764	Methylation	EPTWKTKIADRLKLR CCCCCCHHHHHHCCC	6.12	-
1796	Phosphorylation	AETAKRKSIRRRHTL HHHHHHHHHHHHHCC	25.92	22817900
1797	Phosphorylation	ETAKRKSIRRRHTLG HHHHHHHHHHHHCCC	4.44	-
1802	Phosphorylation	KSIRRRHTLGGHRDA HHHHHHHCCCCCCCC	25.86	22817900
1803	Phosphorylation	SIRRRHTLGGHRDAT HHHHHHCCCCCCCCC	6.72	24719451
1810	Phosphorylation	LGGHRDATEISVLNF CCCCCCCCEEEEEEE	37.83	20068231
1813	Phosphorylation	HRDATEISVLNFWKV CCCCCEEEEEEEEEE	17.83	21406692
1824	Phosphorylation	FWKVHEQSGERESEL EEEECCCCCCCHHHH	39.37	21406692
1829	Phosphorylation	EQSGERESELSAVNR CCCCCCHHHHHHHHH	50.49	28555341
1842	Phosphorylation	NRLKPKCSAQDLSIS HHHCCCCCHHHCCHH	34.78	22617229
1843	Phosphorylation	RLKPKCSAQDLSISD HHCCCCCHHHCCHHH	19.17	24719451
1859	Phosphorylation	LARERLRTSTSDLSR HHHHHHHCCCCCCCC	40.73	30266825
1860	Phosphorylation	ARERLRTSTSDLSRG HHHHHHCCCCCCCCC	21.34	30266825
1861	Phosphorylation	RERLRTSTSDLSRGE HHHHHCCCCCCCCCC	26.16	30266825
1862	Phosphorylation	ERLRTSTSDLSRGEI HHHHCCCCCCCCCCC	36.00	30266825
1865	Phosphorylation	RTSTSDLSRGEIGDP HCCCCCCCCCCCCCC	43.14	30266825
1916	Phosphorylation	LLSIPPQSPDQINGE CCCCCCCCCCCCCCC	35.90	-
1917	Phosphorylation	LSIPPQSPDQINGES CCCCCCCCCCCCCCH	32.07	-
1944	Phosphorylation	NAQPHKLSETPGSKA HCCCCCCCCCCCCCC	44.20	29083192
1946	Phosphorylation	QPHKLSETPGSKAEF CCCCCCCCCCCCCCC	29.58	29083192
1949	Phosphorylation	KLSETPGSKAEFHPC CCCCCCCCCCCCCCC	29.87	29083192

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
131	S	Phosphorylation	Kinase	AURKB	Q96GD4	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RHG21_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RHG21_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RHG21_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1382, AND MASSSPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-458; SER-923; TYR-1239;SER-1377; SER-1382; SER-1430; SER-1431; SER-1432; SER-1526 ANDSER-1668, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-474 AND SER-476, ANDMASS SPECTROMETRY.
PubMed: 18220336

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1089; SER-1219; SER-1220AND THR-1282, AND MASS SPECTROMETRY.
PubMed: 17081983