MACF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MACF1_HUMAN
• UniProt AC: Q9UPN3
• Protein Name: Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5
• Gene Name: MACF1
• Organism: Homo sapiens (Human).
• Sequence Length: 7388
• Subcellular Localization: Isoform 2: Cytoplasm, cytoskeleton . Cytoplasm . Golgi apparatus . Cell membrane . Cell projection, ruffle membrane . The phosphorylated form is found in the cytoplasm while the non-phosphorylated form associates with the microtubules (By similarity)
• Protein Description: Isoform 2: F-actin-binding protein which plays a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. [PubMed: 15265687]
• Protein Sequence: MSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLPWNLPLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIKQHTILMSDKTFPQNPVELKALYNQYIHFKETEILAKEREKGRIEELYKLLEVWIEFGRIKLPQGYHPNDVEEEWGKLIIEMLEREKSLRPAVERLELLLQIANKIQNGALNCEEKLTLAKNTLQADAAHLESGQPVQCESDVIMYIQECEGLIRQLQVDLQILRDENYYQLEELAFRVMRLQDELVTLRLECTNLYRKGHFTSLELVPPSTLTTTHLKAEPLTKATHSSSTSWFRKPMTRAELVAISSSEDEGNLRFVYELLSWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLYEGKMSQNFHTSYAETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNEKEEEELAYDWSDNNSNISAKRNYFSELTMELEEKQDVFRSLQDTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENTAYFQFFSDARELESFLRNLQDSIKRKYSCDHNTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRSPDHVLKNTISVKAVCDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKDAIEMASRVEQSYQKVMALWHQLHVNTKSLISWNYLRKDLDLVQTWNLEKLRSSAPGECHQIMKNLQAHYEDFLQDSRDSVLFSVADRLRLEEEVEACKARFQHLMKSMENEDKEETVAKMYISELKNIRLRLEEYEQRVVKRIQSLASSRTDRDAWQDNALRIAEQEHTQEDLQQLRSDLDAVSMKCDSFLHQSPSSSSVPTLRSELNLLVEKMDHVYGLSTVYLNKLKTVDVIVRSIQDAELLVKGYEIKLSQEEVVLADLSALEAHWSTLRHWLSDVKDKNSVFSVLDEEIAKAKVVAEQMSRLTPERNLDLERYQEKGSQLQERWHRVIAQLEIRQSELESIQEVLGDYRACHGTLIKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQQKSPGKRRRMLSSSDAITQEFMDLRTRYTALVTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKELLGWVSTLARNTQGKATSSETKESTDIEKAILEQQVLSEELTTKKEQVSEAIKTSQIFLAKHGHKLSEKEKKQISEQLNALNKAYHDLCDGSANQLQQLQSQLAHQTEQKECRAVAGVIDLGTVEIFPIFKAMQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALISRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEILSWKKAIESGILDRDLANNLKSICIPDVMPHMQLADSAEQNINPGAAVLPCSKSHPKATASQSENLLFQLMTHSYINVQNGQRLLLLDKELMETLTSRDEYQTSPPKVVEIGHQRQKTPEGLQESANVKISGTFSSGWTVRLPEFQFSSQNKEYPDREDCTTEKGKKTTVETEDSSVENPEQDLFVEQKERNPNIDALKVINKVKLEVQRQLIGTQREDQTAVSVRENASRGHLLTIPPAEAEGVPLVVDKDVFSVETPKKEHQPLRNTSFTCQNEQAHTLETEYIHDETGGSHIKPQSKKLQVQVKKTLGIKLELKSETDGNVHPLDKKEMLKKTFLAKDDHKESQEAQNIAGGSMMMSEKTDEEDSGREIFLSCSHPLELLEEATLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVLTLSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPELANMIQIDSSEFSDHRAQIEKQEGIEVCALQNEFLGKDMLIACNQTAEMSCNKVEESERLFQVENQSAQEKVKVRVSDGEQAKKSREISLKEFGCKDQRKPRMSSDAKEFISIINPHNLKGKSLGQVSLTHPYSECDFKLKEVARNNMGNDTNEEQEKAVTKIEIISHMKQSTSCLDSEEIRENQGEVILEVQETYCETSGKLPSEQVLQQPMNARVKSKREKREVIVEESIRTCKPAFLSEEKLYQETAIRDEHDSHIKSQPREMTSSEKGKEADTEMGFSITFKIEESSSQVVPQGISVKHLDALTLFSSKQANEGKVNNLSLCLTLKPEENLSREIACGAQSEPFPCMTPRPEGLHYQESDGKAQVTGPSQISKTDKSFQGTTRQETNYQDSWVTSKTKETKHQISSSNECKEKSYQEVSFDPARGLKLEEITVSRPDSKEVRYLEFSDRKDLHHQGSKSDDKLCGTLKSEIATQELTGEKFLEMANPNVAGLEAGSIEDIVTQRGSRVLGSFLPEKLFKGVSQKENTGQQNAIISPTVLETSEEKTVSLTVCSAVKTEKTPQEKLRESPGSEQTPFMTAPEGKGNGGVNPEPFRATQNVFTRQLCLEHDEKLVSYLSLLRNIEMRTKQIQPLELNLAELQDLLCQAKVLERELKDLTTLVSQELECVNQIIISQPQEVPAQLLKALEKDAKNLQKSLSSVSDTWNSRLLHFQNAVEIEKTKVLNQHTQLEGRLQDLRAWVGNKNLILNSKGSNSEIDVDSLNLCLQQYEDLKQPMAERKAQLDALAFDIQFFISEHAQDLSPQQNRQMLRLLNELQRSFQDILEQTAAQVDALQGHLQQMEQEALVKTLQKQQNTCHQQLEDLCSWVGQAERALAGHQGRTTQQDLSALQKNQSDLKDLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRELTALREKLHQAKEQYEALQEETRVAQKELEEAVTSALQQETEKSKAAKELAENKKKIDALLDWVTSVGSSGGQLLTNLPGMEQLSGASLEKGALDTTDGYMGVNQAPEKLDKQCEMMKARHQELLSQQQNFILATQSAQAFLDQHGHNLTPEEQQMLQQKLGELKEQYSTSLAQSEAELKQVQTLQDELQKFLQDHKEFESWLERSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHKGDLRFVTISGQKVLDMENSFKEGKEPSEIGNLVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLSDTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDHRHVQETTDSILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLLQSIGEVEQNLEGKQVSSLSSGVIQEALATNMKLKQDIARQKSSLEATREMVTRFMETADSTTAAVLQGKLAEVSQRFEQLCLQQQEKESSLKKLLPQAEMFEHLSGKLQQFMENKSRMLASGNQPDQDITHFFQQIQELNLEMEDQQENLDTLEHLVTELSSCGFALDLCQHQDRVQNLRKDFTELQKTVKEREKDASSCQEQLDEFRKLVRTFQKWLKETEGSIPPTETSMSAKELEKQIEHLKSLLDDWASKGTLVEEINCKGTSLENLIMEITAPDSQGKTGSILPSVGSSVGSVNGYHTCKDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLKSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDVSLSTSQVQKELQSINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEAVKQQLEETSEIRSDLEQLDHEVKEAQTLCDELSVLIGEQYLKDELKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQQAKNCPISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELRVTLDPVQLESSLLRSKAMLNEVEKRRSLLEILNSAADILINSSEADEDGIRDEKAGINQNMDAVTEELQAKTGSLEEMTQRLREFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLRAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASQLLHQAEVAQQEFLEVKQRVNSGCVMMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIHVLKLDIEASEAECRHMLEEEGTLDLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEAEALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTAKIQQQIIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELATSGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTASPRTPGPKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSSDEETL ------CCCCHHHHH	50.26	81017785
3	Phosphorylation	-----MSSSDEETLS -----CCCCHHHHHC	54.38	81017793
4	Phosphorylation	----MSSSDEETLSE ----CCCCHHHHHCH	59.33	74103003
10	Phosphorylation	SSDEETLSERSCRSE CCHHHHHCHHHHHCC	38.08	68716007
13	Phosphorylation	EETLSERSCRSERSC HHHHCHHHHHCCHHH	15.16	28152594
16	Phosphorylation	LSERSCRSERSCRSE HCHHHHHCCHHHHCC	41.51	28152594
19	Phosphorylation	RSCRSERSCRSERSY HHHHCCHHHHCCCCC	15.16	28152594
25	Phosphorylation	RSCRSERSYRSERSG HHHHCCCCCCCCCCC	22.35	101544959
26	Phosphorylation	SCRSERSYRSERSGS HHHCCCCCCCCCCCC	25.12	24043423
28	Phosphorylation	RSERSYRSERSGSLS HCCCCCCCCCCCCCC	29.18	24043423
31	Phosphorylation	RSYRSERSGSLSPCP CCCCCCCCCCCCCCC	28.78	22617229
33	Phosphorylation	YRSERSGSLSPCPPG CCCCCCCCCCCCCCC	27.24	27732954
35	Phosphorylation	SERSGSLSPCPPGDT CCCCCCCCCCCCCCC	26.59	22617229
42	Phosphorylation	SPCPPGDTLPWNLPL CCCCCCCCCCCCCCH	40.41	27732954
51 (in isoform 3)	Ubiquitination	-	72.31	-
57	Phosphorylation	HEQKKRKSQDSVLDP HHHHCCCCCCCCCCH	43.16	25307156
60	Phosphorylation	KKRKSQDSVLDPAER HCCCCCCCCCCHHHH	19.55	26552605
86	Acetylation	VQKKTFTKWVNKHLM HHHHHHHHHHHHHHH	44.98	22424773
90	Acetylation	TFTKWVNKHLMKVRK HHHHHHHHHHHHHHH	28.61	19608861
97	Malonylation	KHLMKVRKHINDLYE HHHHHHHHHHHHHHH	52.39	26320211
211	Phosphorylation	TQKVTAGYTGIKCTN HCCCCCCCCCCEECC	10.18	20068231
212	Phosphorylation	QKVTAGYTGIKCTNF CCCCCCCCCCEECCC	31.36	20068231
236	Phosphorylation	FNALIHRYRPDLVDM HHHHHHHHCCCCCCH	16.60	74103105
280	Phosphorylation	AEDVDVPSPDEKSVI HHHCCCCCCCHHHHH	44.85	29255136
291	Phosphorylation	KSVITYVSSIYDAFP HHHHHHHHHHHHHCC	10.70	28857561
292	Phosphorylation	SVITYVSSIYDAFPK HHHHHHHHHHHHCCC	18.34	28857561
294	Phosphorylation	ITYVSSIYDAFPKVP HHHHHHHHHHCCCCC	11.81	12449617
325	Phosphorylation	EYQSRVDSLIPWIKQ HHHHHHHHHHHHHHH	25.91	28857561
334	Phosphorylation	IPWIKQHTILMSDKT HHHHHHHHHCCCCCC	17.20	29396449
353	Phosphorylation	PVELKALYNQYIHFK HHHHHHHHHHHCCHH	12.70	21406692
356	Phosphorylation	LKALYNQYIHFKETE HHHHHHHHCCHHHHH	7.85	21406692
378	Phosphorylation	KGRIEELYKLLEVWI HCHHHHHHHHHHHHH	11.67	21406692
518	Phosphorylation	RLQDELVTLRLECTN HHHHHHHHHEHHEEC	20.84	20068231
533	Phosphorylation	LYRKGHFTSLELVPP CEECCCCEEEEECCC	27.08	23403867
534	Phosphorylation	YRKGHFTSLELVPPS EECCCCEEEEECCCC	20.92	23403867
559	Phosphorylation	PLTKATHSSSTSWFR CCCCCCCCCCCCCCC	22.94	50563143
560	Phosphorylation	LTKATHSSSTSWFRK CCCCCCCCCCCCCCC	29.99	50563163
561	Phosphorylation	TKATHSSSTSWFRKP CCCCCCCCCCCCCCC	29.49	28857561
563	Phosphorylation	ATHSSSTSWFRKPMT CCCCCCCCCCCCCCC	26.60	50563183
642	Phosphorylation	SVKEARLYEGKMSQN CHHHHHHHCCCCCCC	19.65	26657352
647	Phosphorylation	RLYEGKMSQNFHTSY HHHCCCCCCCCCHHH	26.00	21406692
652	Phosphorylation	KMSQNFHTSYAETLG CCCCCCCHHHHHHHH	21.21	26657352
653	Phosphorylation	MSQNFHTSYAETLGK CCCCCCHHHHHHHHH	17.49	21406692
654	Phosphorylation	SQNFHTSYAETLGKL CCCCCHHHHHHHHHH	15.04	26657352
657	Phosphorylation	FHTSYAETLGKLETQ CCHHHHHHHHHHHHH	32.41	21406692
681	Phosphorylation	FRMRHLQSLHKFVSR HHHHHHHHHHHHHHH	38.51	28509920
706	Phosphorylation	KEEEELAYDWSDNNS CHHHHHCCCCCCCCC	30.48	50563107
721	Phosphorylation	NISAKRNYFSELTME CHHHCHHHHHHHHHH	16.71	23322592
747	Phosphorylation	QDTAELLSLENHPAK HHHHHHHCCCCCCHH	46.38	82900275
810	Malonylation	RNLQDSIKRKYSCDH HHHHHHHHHHHCCCC	46.95	26320211
813	Phosphorylation	QDSIKRKYSCDHNTS HHHHHHHHCCCCCCC	20.68	20873877
814	Phosphorylation	DSIKRKYSCDHNTSL HHHHHHHCCCCCCCH	18.99	20873877
819	Phosphorylation	KYSCDHNTSLSRLED HHCCCCCCCHHHHHH	27.85	23927012
820	Phosphorylation	YSCDHNTSLSRLEDL HCCCCCCCHHHHHHH	29.66	72251707
822	Phosphorylation	CDHNTSLSRLEDLLQ CCCCCCHHHHHHHHH	34.29	23927012
831	Phosphorylation	LEDLLQDSMDEKEQL HHHHHHCCCCHHHHH	18.38	110760513
835	Acetylation	LQDSMDEKEQLIQSK HHCCCCHHHHHHHCH	46.63	26051181
847	Phosphorylation	QSKSSVASLVGRSKT HCHHHHHHHHCCCCE	22.79	101544999
862	Phosphorylation	IVQLKPRSPDHVLKN EEECCCCCCCCCCCC	43.11	23312004
885	Phosphorylation	DYRQIEITICKNDEC CCEEEEEEEECCCEE	13.92	-
898	Phosphorylation	ECVLEDNSQRTKWKV EEEEECCCCCCEEEE	33.10	-
901	Phosphorylation	LEDNSQRTKWKVISP EECCCCCCEEEEECC	33.35	-
907	Phosphorylation	RTKWKVISPTGNEAM CCEEEEECCCCCCCC	21.28	28348404
909	Phosphorylation	KWKVISPTGNEAMVP EEEEECCCCCCCCCC	45.94	28348404
962	Phosphorylation	KSLISWNYLRKDLDL HHHHCHHHHHCCCCH	11.13	-
972	Phosphorylation	KDLDLVQTWNLEKLR CCCCHHHHCCHHHHH	14.61	29083192
1035	Phosphorylation	RFQHLMKSMENEDKE HHHHHHHHCCCCCHH	19.84	28509920
1063	Phosphorylation	IRLRLEEYEQRVVKR HHHHHHHHHHHHHHH	14.16	18083107
1073	Phosphorylation	RVVKRIQSLASSRTD HHHHHHHHHHHCCCC	24.43	21712546
1076	Phosphorylation	KRIQSLASSRTDRDA HHHHHHHHCCCCHHH	26.16	63745747
1077	Phosphorylation	RIQSLASSRTDRDAW HHHHHHHCCCCHHHH	33.32	63745753
1102	Ubiquitination	EHTQEDLQQLRSDLD HCCHHHHHHHHHHHH	53.21	21890473
1102	Ubiquitination	EHTQEDLQQLRSDLD HCCHHHHHHHHHHHH	53.21	21890473
1117	Phosphorylation	AVSMKCDSFLHQSPS HHHHHCHHHHHCCCC	38.90	23186163
1122	Phosphorylation	CDSFLHQSPSSSSVP CHHHHHCCCCCCCCC	18.92	25159151
1124	Phosphorylation	SFLHQSPSSSSVPTL HHHHCCCCCCCCCCH	48.36	23186163
1125	Phosphorylation	FLHQSPSSSSVPTLR HHHCCCCCCCCCCHH	29.98	23186163
1126	Phosphorylation	LHQSPSSSSVPTLRS HHCCCCCCCCCCHHH	39.43	23186163
1127	Phosphorylation	HQSPSSSSVPTLRSE HCCCCCCCCCCHHHH	33.78	23186163
1146	Phosphorylation	VEKMDHVYGLSTVYL HHHCCCCCCCCHHHH	14.66	23917254
1152	Phosphorylation	VYGLSTVYLNKLKTV CCCCCHHHHCCCCCC	12.49	-
1158	Phosphorylation	VYLNKLKTVDVIVRS HHHCCCCCCEEEEEC	32.16	20068231
1191	Phosphorylation	EVVLADLSALEAHWS HHHHHHHHHHHHHHH	31.21	50563115
1212	Phosphorylation	SDVKDKNSVFSVLDE HCCCCCCCHHHHCCH	30.22	30242111
1215	Phosphorylation	KDKNSVFSVLDEEIA CCCCCHHHHCCHHHH	21.44	30242111
1294	Phosphorylation	LIKWIEETTAQQEMM HHHHHHHHHHHHHHC	18.03	27794612
1295	Phosphorylation	IKWIEETTAQQEMMK HHHHHHHHHHHHHCC	26.25	27794612
1343	Phosphorylation	CQKFSQQYSTIVKDY HHHHHHHHHHHHHHH	10.51	-
1344	Phosphorylation	QKFSQQYSTIVKDYE HHHHHHHHHHHHHHH	13.81	24275569
1350	Phosphorylation	YSTIVKDYELQLMTY HHHHHHHHHHHHHHH	16.90	26074081
1356	Phosphorylation	DYELQLMTYKAFVES HHHHHHHHHHHHHHH	30.38	26074081
1357	Phosphorylation	YELQLMTYKAFVESQ HHHHHHHHHHHHHHH	6.07	26074081
1363	Phosphorylation	TYKAFVESQQKSPGK HHHHHHHHHCCCCCH	32.39	23927012
1367	Phosphorylation	FVESQQKSPGKRRRM HHHHHCCCCCHHHHC	34.25	23401153
1376	Phosphorylation	GKRRRMLSSSDAITQ CHHHHCCCCHHHHHH	20.60	23927012
1377	Phosphorylation	KRRRMLSSSDAITQE HHHHCCCCHHHHHHH	28.42	27273156
1378	Phosphorylation	RRRMLSSSDAITQEF HHHCCCCHHHHHHHH	27.90	23927012
1382	Phosphorylation	LSSSDAITQEFMDLR CCCHHHHHHHHHHHH	24.62	23403867
1477	2-Hydroxyisobutyrylation	LSEELTTKKEQVSEA HCHHHCCCHHHHHHH	49.42	-
1482	Phosphorylation	TTKKEQVSEAIKTSQ CCCHHHHHHHHHHHH	22.47	26074081
1487	Phosphorylation	QVSEAIKTSQIFLAK HHHHHHHHHHHHHHH	21.54	26074081
1488	Phosphorylation	VSEAIKTSQIFLAKH HHHHHHHHHHHHHHC	19.10	26074081
1500	Phosphorylation	AKHGHKLSEKEKKQI HHCCCCCCHHHHHHH	51.96	26074081
1505	Malonylation	KLSEKEKKQISEQLN CCCHHHHHHHHHHHH	54.69	26320211
1614	Phosphorylation	NLINPQMYQQLRELQ HCCCHHHHHHHHHHH	6.45	27067055
1628	Phosphorylation	QDALALISRLTESRG HHHHHHHHHHHHCCC	23.30	50559009
1638	Phosphorylation	TESRGPLSVVEAIEK HHCCCCCHHHHHHHH	27.53	1998385
1702	Ubiquitination	ESYLRTSKNLIDPNT HHHHHCCCCCCCCCH	55.98	-
1712	Ubiquitination	IDPNTAEKIGLLDLM CCCCHHHHCCHHHHH	39.34	-
1714	Ubiquitination	PNTAEKIGLLDLMQR CCHHHHCCHHHHHHH	31.12	21890473
1714	Ubiquitination	PNTAEKIGLLDLMQR CCHHHHCCHHHHHHH	31.12	21890473
1736	Acetylation	GFKLLPVKQLAGGMV CCEEEEHHHHCCCEE	37.34	7977285
1736	Ubiquitination	GFKLLPVKQLAGGMV CCEEEEHHHHCCCEE	37.34	-
1744	Phosphorylation	QLAGGMVSLKSGRKV HHCCCEEECCCCCCE	22.61	55146009
1746	Acetylation	AGGMVSLKSGRKVSI CCCEEECCCCCCEEE	43.27	7977293
1749	Methylation	MVSLKSGRKVSIFRA EEECCCCCCEEEEHH	43.20	-
1750	Acetylation	VSLKSGRKVSIFRAV EECCCCCCEEEEHHH	43.81	7977301
1752	Phosphorylation	LKSGRKVSIFRAVQE CCCCCCEEEEHHHHC	21.03	24702127
1767	Phosphorylation	GLIDRQVTVRLLEAQ CCCCCHHHHHHHHHH	7.50	24719451
1892	Acetylation	LSNRQHIKALFLPAT HCCCHHHHHHHCCCH	36.59	24848993
1893	Ubiquitination	SNRQHIKALFLPATT CCCHHHHHHHCCCHH	11.71	21890473
1893	Ubiquitination	SNRQHIKALFLPATT CCCHHHHHHHCCCHH	11.71	21890473
1941	Ubiquitination	MQLADSAEQNINPGA CHHHHCHHCCCCCCC	48.38	21890473
1941	Ubiquitination	MQLADSAEQNINPGA CHHHHCHHCCCCCCC	48.38	21890473
1998	Phosphorylation	KELMETLTSRDEYQT HHHHHHHCCCCCCCC	29.18	25627689
2003	Phosphorylation	TLTSRDEYQTSPPKV HHCCCCCCCCCCCCE	22.75	28796482
2005	Phosphorylation	TSRDEYQTSPPKVVE CCCCCCCCCCCCEEE	42.15	23186163
2006	Phosphorylation	SRDEYQTSPPKVVEI CCCCCCCCCCCEEEE	24.55	23401153
2019	Ubiquitination	EIGHQRQKTPEGLQE EECCCCCCCCCHHHH	69.13	-
2020	Phosphorylation	IGHQRQKTPEGLQES ECCCCCCCCCHHHHC	20.45	25159151
2035	Phosphorylation	ANVKISGTFSSGWTV CCEEEEEEECCCEEE	17.35	25307156
2038	Phosphorylation	KISGTFSSGWTVRLP EEEEEECCCEEEECC	33.87	25307156
2041	Phosphorylation	GTFSSGWTVRLPEFQ EEECCCEEEECCCEE	10.16	25307156
2050	Phosphorylation	RLPEFQFSSQNKEYP ECCCEECCCCCCCCC	21.89	23186163
2051	Phosphorylation	LPEFQFSSQNKEYPD CCCEECCCCCCCCCC	38.78	23917254
2063	Phosphorylation	YPDREDCTTEKGKKT CCCHHHCCCCCCCEE	50.76	29507054
2064	Phosphorylation	PDREDCTTEKGKKTT CCHHHCCCCCCCEEE	41.87	29507054
2070	Phosphorylation	TTEKGKKTTVETEDS CCCCCCEEEEECCCC	39.29	23403867
2077	Phosphorylation	TTVETEDSSVENPEQ EEEECCCCCCCCHHH	30.01	20068231
2078	Phosphorylation	TVETEDSSVENPEQD EEECCCCCCCCHHHC	45.85	23403867
2157	Phosphorylation	VVDKDVFSVETPKKE EEECCCEECCCCCCC	20.92	29396449
2160	Phosphorylation	KDVFSVETPKKEHQP CCCEECCCCCCCCCC	37.95	22199227
2172	Phosphorylation	HQPLRNTSFTCQNEQ CCCCCCCCEEECCCC	23.31	118537
2204 (in isoform 1)	Ubiquitination	-	7.48	21890473
2220	Phosphorylation	GIKLELKSETDGNVH CCEEEEEECCCCCCC	59.35	22190199
2238	Phosphorylation	KKEMLKKTFLAKDDH HHHHHHHHHHCCCCC	23.46	46157677
2239 (in isoform 2)	Ubiquitination	-	9.55	21890473
2239 (in isoform 4)	Ubiquitination	-	9.55	21890473
2248	Phosphorylation	AKDDHKESQEAQNIA CCCCCHHHHHHHHHC	37.82	50563151
2258	Phosphorylation	AQNIAGGSMMMSEKT HHHHCCCCCHHCCCC	11.55	68713859
2262	Phosphorylation	AGGSMMMSEKTDEED CCCCCHHCCCCCCCC	20.32	50563179
2343	Phosphorylation	MFQGFFDSQTCESLT CCCCCCCCHHHCCCC	23.41	30576142
2351	Phosphorylation	QTCESLTTEEVINEG HHHCCCCHHHHHHCC	35.13	30576142
2362	Phosphorylation	INEGLMDEKLLHNVL HHCCCCCHHHHHHHH	31.47	17081983
2426	Phosphorylation	LKRGKKVSVTLASTL CCCCCEEEEEEHHHC	20.47	22254441
2431	Phosphorylation	KVSVTLASTLGLVDV EEEEEEHHHCCCCCC	27.55	22254447
2466	Phosphorylation	TVRERLISLQMETTG HHHHHHHHHHCCCCC	19.69	24719451
2479	Phosphorylation	TGLIDPDSKAPLTVV CCCCCCCCCCCEEEE	35.78	46157645
2517	Phosphorylation	GGIIHHISGMRLSVD CCCHHHCCCCCCCCC	23.37	68740099
2561	Phosphorylation	PETKENISLPKAIKL CCCCCCCCCCCHHCH	50.64	24719451
2586	Phosphorylation	IQEVQAFTGNFVDLI HHHHHHHHCCHHHHH	33.94	25003641
2594	Phosphorylation	GNFVDLISGQRLTLA CCHHHHHCCCEEEHH	35.85	25003641
2642	Ubiquitination	SELVKKCKIDIESGQ HHHHHHCCCCCCCCC	52.90	-
2647	Phosphorylation	KCKIDIESGQRYLEV HCCCCCCCCCEEEEE	40.33	68712299
2667	Ubiquitination	IKDGVSDKVLTLSQA CCCCCCHHHCCHHHH	31.47	21890473
2741	Ubiquitination	GGIVDIFSDQRVTLV CCEEEECCCCCCHHH	32.92	21890473
2741	Ubiquitination	GGIVDIFSDQRVTLV CCEEEECCCCCCHHH	32.92	21890473
2836	Phosphorylation	EKVKVRVSDGEQAKK CCCEEECCCHHHHHH	29.36	29514088
2892	Phosphorylation	QVSLTHPYSECDFKL CEECCCCCCCCCHHH	14.97	22353049
2893	Phosphorylation	VSLTHPYSECDFKLK EECCCCCCCCCHHHH	35.88	30823959
2911	Phosphorylation	RNNMGNDTNEEQEKA HHCCCCCCCHHHHHH	48.83	28851738
2920	Phosphorylation	EEQEKAVTKIEIISH HHHHHHHHHHHHHHH	31.03	7208907
2926	Phosphorylation	VTKIEIISHMKQSTS HHHHHHHHHCCCCCC	24.16	23403867
2931	Phosphorylation	IISHMKQSTSCLDSE HHHHCCCCCCCCCHH	19.44	19664994
2933	Phosphorylation	SHMKQSTSCLDSEEI HHCCCCCCCCCHHHH	20.23	10952871
2956	Phosphorylation	LEVQETYCETSGKLP EEEEEHHHCCCCCCC	6.33	17081983
2958	Phosphorylation	VQETYCETSGKLPSE EEEHHHCCCCCCCHH	38.94	26074081
2959	Phosphorylation	QETYCETSGKLPSEQ EEHHHCCCCCCCHHH	16.19	26074081
2964	Phosphorylation	ETSGKLPSEQVLQQP CCCCCCCHHHHHHCC	51.61	26074081
2990	Phosphorylation	REVIVEESIRTCKPA CCHHHHHHHHHCCCC	12.13	25599653
3000	Phosphorylation	TCKPAFLSEEKLYQE HCCCCCCCHHHHHHH	36.94	23403867
3005	Phosphorylation	FLSEEKLYQETAIRD CCCHHHHHHHHHCCC	18.51	30460933
3016	Phosphorylation	AIRDEHDSHIKSQPR HCCCCCHHHHHCCCC	29.08	68698067
3020	Phosphorylation	EHDSHIKSQPREMTS CCHHHHHCCCCCCCC	44.83	68698073
3083	Phosphorylation	EGKVNNLSLCLTLKP CCCCCCEEEEEEECC	21.11	21406692
3087	Phosphorylation	NNLSLCLTLKPEENL CCEEEEEEECCCCCC	31.57	21406692
3111	Phosphorylation	SEPFPCMTPRPEGLH CCCCCCCCCCCCCCC	23.90	46157651
3119	Phosphorylation	PRPEGLHYQESDGKA CCCCCCCEECCCCCE	21.01	17053785
3122	Phosphorylation	EGLHYQESDGKAQVT CCCCEECCCCCEEEC	35.82	-
3151	Phosphorylation	TTRQETNYQDSWVTS CCCCCCCCCCCCCCC	22.55	30854061
3163	Phosphorylation	VTSKTKETKHQISSS CCCCCCCCCHHCCCC	35.07	50563131
3168	Phosphorylation	KETKHQISSSNECKE CCCCHHCCCCHHHHH	22.57	24702127
3169	Phosphorylation	ETKHQISSSNECKEK CCCHHCCCCHHHHHH	38.52	24702127
3170	Phosphorylation	TKHQISSSNECKEKS CCHHCCCCHHHHHHH	29.83	24702127
3177	Phosphorylation	SNECKEKSYQEVSFD CHHHHHHHCCCCCCC	32.89	28796482
3178	Phosphorylation	NECKEKSYQEVSFDP HHHHHHHCCCCCCCC	21.54	28796482
3206	Phosphorylation	PDSKEVRYLEFSDRK CCCCCEEEEECCCCC	18.76	30823943
3220	Phosphorylation	KDLHHQGSKSDDKLC CCCCCCCCCCCCCHH	23.55	28857561
3222	Phosphorylation	LHHQGSKSDDKLCGT CCCCCCCCCCCHHHH	53.38	82900271
3229	Phosphorylation	SDDKLCGTLKSEIAT CCCCHHHHHHHHHHH	29.98	46157655
3265	Phosphorylation	GSIEDIVTQRGSRVL CCHHHHHHHCCCHHH	16.94	24719451
3269	Phosphorylation	DIVTQRGSRVLGSFL HHHHHCCCHHHHHHC	22.77	37816965
3274	Phosphorylation	RGSRVLGSFLPEKLF CCCHHHHHHCCHHHH	21.32	29396449
3279	Ubiquitination	LGSFLPEKLFKGVSQ HHHHCCHHHHCCCCC	58.23	21890473
3285	Phosphorylation	EKLFKGVSQKENTGQ HHHHCCCCCCCCCCC	44.17	26434776
3290	Phosphorylation	GVSQKENTGQQNAII CCCCCCCCCCCCCEE	37.14	23403867
3298	Phosphorylation	GQQNAIISPTVLETS CCCCCEECCCEECCC	14.38	26657352
3300	Phosphorylation	QNAIISPTVLETSEE CCCEECCCEECCCCC	30.82	23403867
3304	Phosphorylation	ISPTVLETSEEKTVS ECCCEECCCCCCEEE	36.96	23403867
3305	Phosphorylation	SPTVLETSEEKTVSL CCCEECCCCCCEEEE	34.09	23403867
3311	Phosphorylation	TSEEKTVSLTVCSAV CCCCCEEEEEEECCC	24.45	20068231
3313	Phosphorylation	EEKTVSLTVCSAVKT CCCEEEEEEECCCCC	16.38	20068231
3320	Phosphorylation	TVCSAVKTEKTPQEK EEECCCCCCCCCHHH	35.79	29759185
3323	Phosphorylation	SAVKTEKTPQEKLRE CCCCCCCCCHHHHHC	24.79	29759185
3331	Phosphorylation	PQEKLRESPGSEQTP CHHHHHCCCCCCCCC	28.29	23401153
3334	Phosphorylation	KLRESPGSEQTPFMT HHHCCCCCCCCCCCC	29.89	30266825
3337	Phosphorylation	ESPGSEQTPFMTAPE CCCCCCCCCCCCCCC	17.91	30266825
3380	Phosphorylation	EKLVSYLSLLRNIEM HHHHHHHHHHHCHHH	19.68	23403867
3396 (in isoform 3)	Phosphorylation	-	42.15	27251275
3398 (in isoform 3)	Phosphorylation	-	28.03	27251275
3399 (in isoform 3)	Phosphorylation	-	6.48	27251275
3439 (in isoform 3)	Phosphorylation	-	57.60	25159151
3452 (in isoform 2)	Phosphorylation	-	54.09	27251275
3454 (in isoform 2)	Phosphorylation	-	69.22	27251275
3455 (in isoform 2)	Phosphorylation	-	49.80	27251275
3458	Ubiquitination	KDAKNLQKSLSSVSD HHHHHHHHHHHHCHH	57.43	21890473
3459	Phosphorylation	DAKNLQKSLSSVSDT HHHHHHHHHHHCHHH	22.11	29978859
3461	Phosphorylation	KNLQKSLSSVSDTWN HHHHHHHHHCHHHHH	35.47	29978859
3462	Phosphorylation	NLQKSLSSVSDTWNS HHHHHHHHCHHHHHH	30.82	29978859
3490	Phosphorylation	TKVLNQHTQLEGRLQ HHHHCCHHHHHHHHH	25.70	28787133
3495 (in isoform 2)	Phosphorylation	-	21.57	25159151
3506	Ubiquitination	LRAWVGNKNLILNSK HHHHHCCCCEEECCC	47.40	21890473
3644	Phosphorylation	LAGHQGRTTQQDLSA HCCCCCCCHHHHHHH	35.46	20068231
3650	Phosphorylation	RTTQQDLSALQKNQS CCHHHHHHHHHHCHH	34.91	36023839
3657	Phosphorylation	SALQKNQSDLKDLQD HHHHHCHHHHHHHHH	55.06	68998397
3671	Phosphorylation	DDIQNRATSFATVVK HHHHHHHHHHHHHHH	22.57	28851738
3675	Phosphorylation	NRATSFATVVKDIEG HHHHHHHHHHHHHHH	24.66	28851738
3689	Phosphorylation	GFMEENQTKLSPREL HHHHHCCCCCCHHHH	45.60	113334105
3692	Phosphorylation	EENQTKLSPRELTAL HHCCCCCCHHHHHHH	24.38	30108239
3697	Phosphorylation	KLSPRELTALREKLH CCCHHHHHHHHHHHH	20.92	113334113
3702	2-Hydroxyisobutyrylation	ELTALREKLHQAKEQ HHHHHHHHHHHHHHH	44.85	-
3710	Phosphorylation	LHQAKEQYEALQEET HHHHHHHHHHHHHHH	12.31	22468782
3729	Phosphorylation	KELEEAVTSALQQET HHHHHHHHHHHHHHH	18.48	20068231
3730	Phosphorylation	ELEEAVTSALQQETE HHHHHHHHHHHHHHH	22.00	20068231
3736	Phosphorylation	TSALQQETEKSKAAK HHHHHHHHHHHHHHH	44.36	20068231
3739	Phosphorylation	LQQETEKSKAAKELA HHHHHHHHHHHHHHH	22.69	20068231
3760	Phosphorylation	DALLDWVTSVGSSGG HHHHHHHHHCCCHHH	17.28	21406692
3761	Phosphorylation	ALLDWVTSVGSSGGQ HHHHHHHHCCCHHHC	18.18	21406692
3764	Phosphorylation	DWVTSVGSSGGQLLT HHHHHCCCHHHCHHH	24.53	21406692
3765	Phosphorylation	WVTSVGSSGGQLLTN HHHHCCCHHHCHHHC	40.80	21406692
3771	Phosphorylation	SSGGQLLTNLPGMEQ CHHHCHHHCCCCHHH	43.21	21406692
3780	Phosphorylation	LPGMEQLSGASLEKG CCCHHHHCCCCCCCC	31.82	21406692
3783	Phosphorylation	MEQLSGASLEKGALD HHHHCCCCCCCCCCC	40.35	21406692
3791	Phosphorylation	LEKGALDTTDGYMGV CCCCCCCCCCCCCCC	27.86	21945579
3792	Phosphorylation	EKGALDTTDGYMGVN CCCCCCCCCCCCCCC	27.39	21945579
3795	Phosphorylation	ALDTTDGYMGVNQAP CCCCCCCCCCCCCCC	8.10	21945579
3870	Phosphorylation	YSTSLAQSEAELKQV HHHCHHHCHHHHHHH	32.92	34866429
3913	Phosphorylation	ENMHKGGSSPETLPS HHHHCCCCCCHHHHH	51.92	25307156
3914	Phosphorylation	NMHKGGSSPETLPSL HHHCCCCCCHHHHHH	29.99	25159151
3917	Phosphorylation	KGGSSPETLPSLLKR CCCCCCHHHHHHHHH	47.56	23186163
3920	Phosphorylation	SSPETLPSLLKRQGS CCCHHHHHHHHHCCC	49.82	24719451
3927	Phosphorylation	SLLKRQGSFSEDVIS HHHHHCCCCCCCCCC	19.77	29255136
3929	Phosphorylation	LKRQGSFSEDVISHK HHHCCCCCCCCCCCC	34.29	29255136
3934	Phosphorylation	SFSEDVISHKGDLRF CCCCCCCCCCCCEEE	20.99	23927012
3954 (in isoform 5)	Phosphorylation	-	46.22	27251275
3956 (in isoform 5)	Phosphorylation	-	14.58	27251275
3957 (in isoform 5)	Phosphorylation	-	66.43	27251275
3977	Phosphorylation	KDKLKDATERYTALH HHHHHHHHHHHHHHH	31.00	22210691
3980	Phosphorylation	LKDATERYTALHSKC HHHHHHHHHHHHHHH	10.31	46157683
3981	Phosphorylation	KDATERYTALHSKCT HHHHHHHHHHHHHHH	29.03	22210691
3985	Phosphorylation	ERYTALHSKCTRLGS HHHHHHHHHHHHHHH	30.21	22210691
3997 (in isoform 5)	Phosphorylation	-	4.77	25159151
4105	Phosphorylation	YSLAERSSLLQKAIA HHHHHHHHHHHHHHH	39.04	24719451
4141	Phosphorylation	NLEGKQVSSLSSGVI HHCCCCHHHCCHHHH	24.06	20068231
4142	Phosphorylation	LEGKQVSSLSSGVIQ HCCCCHHHCCHHHHH	33.15	20068231
4144	Phosphorylation	GKQVSSLSSGVIQEA CCCHHHCCHHHHHHH	27.30	20068231
4145	Phosphorylation	KQVSSLSSGVIQEAL CCHHHCCHHHHHHHH	42.23	20068231
4154	Phosphorylation	VIQEALATNMKLKQD HHHHHHHHCCHHHHH	36.37	20068231
4167	Phosphorylation	QDIARQKSSLEATRE HHHHHHHHHHHHHHH	31.64	187111
4168	Phosphorylation	DIARQKSSLEATREM HHHHHHHHHHHHHHH	36.95	24245541
4187	Phosphorylation	METADSTTAAVLQGK HHHCCHHHHHHHHHH	19.30	30576142
4306	Ubiquitination	DRVQNLRKDFTELQK HHHHHHHHHHHHHHH	61.43	2189047
4309	Phosphorylation	QNLRKDFTELQKTVK HHHHHHHHHHHHHHH	46.01	21406692
4323	Phosphorylation	KEREKDASSCQEQLD HHHHHCHHHHHHHHH	41.60	22817900
4324	O-linked_Glycosylation	EREKDASSCQEQLDE HHHHCHHHHHHHHHH	22.88	30379171
4355	Phosphorylation	GSIPPTETSMSAKEL CCCCCCCCCCCHHHH	32.01	27251789
4371	Phosphorylation	KQIEHLKSLLDDWAS HHHHHHHHHHHHHHH	40.29	46157603
4391	Phosphorylation	EEINCKGTSLENLIM EEEECCCCCHHHHEE	18.68	24719451
4392	Phosphorylation	EINCKGTSLENLIME EEECCCCCHHHHEEE	42.21	26657352
4415	Phosphorylation	KTGSILPSVGSSVGS CCCCCCCCCCCCCCC	35.35	46157609
4459	Phosphorylation	VLHERQESLQAILNR HHHHHHHHHHHHHHH	19.90	50563123
4476	Phosphorylation	EVHKEANSVLQWLES HHHHHHHHHHHHHHC	31.11	50563155
4483	Phosphorylation	SVLQWLESKEEVLKS HHHHHHHCHHHHHHH	43.10	29151543
4490	Phosphorylation	SKEEVLKSMDAMSSP CHHHHHHHHHCCCCC	20.10	23927012
4495	Phosphorylation	LKSMDAMSSPTKTET HHHHHCCCCCCCCHH	34.58	23401153
4496	Phosphorylation	KSMDAMSSPTKTETV HHHHCCCCCCCCHHH	24.41	19664994
4498	Phosphorylation	MDAMSSPTKTETVKA HHCCCCCCCCHHHHH	53.17	30266825
4500	Phosphorylation	AMSSPTKTETVKAQA CCCCCCCCHHHHHHH	39.09	30266825
4502	Phosphorylation	SSPTKTETVKAQAES CCCCCCHHHHHHHHH	32.32	23927012
4509	Phosphorylation	TVKAQAESNKAFLAE HHHHHHHHCHHHHHH	46.80	26074081
4521	Phosphorylation	LAELEQNSPKIQKVK HHHHHHCCHHHHHHH	27.54	19664994
4556	Phosphorylation	KIQEELNSRWERATE HHHHHHHHHHHHHHH	51.93	29255136
4562	Phosphorylation	NSRWERATEVTVARQ HHHHHHHHHHHHHHH	36.89	21406692
4565	Phosphorylation	WERATEVTVARQRQL HHHHHHHHHHHHHHH	11.38	21406692
4625	Sumoylation	QQVQFMLKEFEARRQ HHHHHHHHHHHHHHH	48.87	-
4646	Phosphorylation	EAAQGILTGPGDVSL HHHHHHHCCCCCCCC	39.13	68708793
4673	Phosphorylation	NQKWVELTDKLNSRS HHHHHHHHHHHHCCC	19.99	37816983
4678	Phosphorylation	ELTDKLNSRSSQIDQ HHHHHHHCCCHHHHH	43.93	21406692
4680	Phosphorylation	TDKLNSRSSQIDQAI HHHHHCCCHHHHHHH	26.81	29083192
4681	Phosphorylation	DKLNSRSSQIDQAIV HHHHCCCHHHHHHHH	30.00	29083192
4690	Phosphorylation	IDQAIVKSTQYQELL HHHHHHHHHHHHHHH	15.17	29083192
4691	Phosphorylation	DQAIVKSTQYQELLQ HHHHHHHHHHHHHHH	26.10	29083192
4693	Phosphorylation	AIVKSTQYQELLQDL HHHHHHHHHHHHHHH	12.21	29083192
4701	Phosphorylation	QELLQDLSEKVRAVG HHHHHHHHHHHHHHH	43.60	29083192
4789	Methylation	LEDLAADRINRLQAA HHHHHHHHHHHHHHH	24.29	-
4799	Phosphorylation	RLQAALASTQQFQQM HHHHHHHHHHHHHHH	27.83	20873877
4800	Phosphorylation	LQAALASTQQFQQMF HHHHHHHHHHHHHHH	22.30	20873877
4812	Phosphorylation	QMFDELRTWLDDKQS HHHHHHHHHHCHHHH	42.90	20873877
4836	Phosphorylation	AKLERLQSQLQENEE HHHHHHHHHHHCCHH	37.13	23911959
4946	Phosphorylation	DPVQLESSLLRSKAM CHHHHHHHHHHHHHH	23.27	24719451
4950	Phosphorylation	LESSLLRSKAMLNEV HHHHHHHHHHHHHHH	25.41	29743597
4959	2-Hydroxyisobutyrylation	AMLNEVEKRRSLLEI HHHHHHHHHHHHHHH	59.28	-
4962	Phosphorylation	NEVEKRRSLLEILNS HHHHHHHHHHHHHHH	41.14	26657352
4969	Phosphorylation	SLLEILNSAADILIN HHHHHHHHHHHHHHC	22.76	21406692
5007	Phosphorylation	TEELQAKTGSLEEMT HHHHHHHCCCHHHHH	34.71	28857561
5009	Phosphorylation	ELQAKTGSLEEMTQR HHHHHCCCHHHHHHH	37.53	20068231
5014	Phosphorylation	TGSLEEMTQRLREFQ CCCHHHHHHHHHHHH	17.51	20068231
5114	Phosphorylation	EVKQRVNSGCVMMEN HHHHHHHCCCEEECC	30.61	113334097
5327	Phosphorylation	EINARWNTLNKKVAQ HHHHHHHHHHHHHHH	25.42	27422710
5331	Ubiquitination	RWNTLNKKVAQRIAQ HHHHHHHHHHHHHHH	41.55	-
5400	Phosphorylation	LLDDRKATVDMLQAE HHHHHHCHHHHHHHC	21.77	37816977
5403	Sulfoxidation	DRKATVDMLQAEGGR HHHCHHHHHHHCCCH	2.31	21406390
5422	2-Hydroxyisobutyrylation	AELADREKITGQLES HHHHCHHHHHHHHHH	46.60	-
5429	Phosphorylation	KITGQLESLESRWTE HHHHHHHHHHHHHHH	46.13	30576142
5435	Phosphorylation	ESLESRWTELLSKAA HHHHHHHHHHHHHHH	18.69	-
5486	Phosphorylation	SEPVGTQTAKIQQQI CCCCCHHHHHHHHHH	29.74	50563135
5543	Phosphorylation	LDGIKTRYADITVTS HCCCCCCCCCEEECC	17.54	51927
5587	Phosphorylation	EVEEELATSGGQSPT HHHHHHHHCCCCCCC	40.29	30266825
5588	Phosphorylation	VEEELATSGGQSPTG HHHHHHHCCCCCCCC	35.01	30266825
5592	Phosphorylation	LATSGGQSPTGEQIP HHHCCCCCCCCCCCC	27.92	30266825
5594	Phosphorylation	TSGGQSPTGEQIPQF HCCCCCCCCCCCCHH	59.61	30266825
5621	O-linked_Glycosylation	EHRLVLDTVNEVSRA HHHHHHHHHHHHHHH	22.52	30379171
5621	Phosphorylation	EHRLVLDTVNEVSRA HHHHHHHHHHHHHHH	22.52	21406692
5626	Phosphorylation	LDTVNEVSRALLELV HHHHHHHHHHHHHHC	12.98	21406692
5627	Phosphorylation	DTVNEVSRALLELVP HHHHHHHHHHHHHCC	34.14	16097034
5718	Phosphorylation	LQVQKAFSIDIIRHK HHHHHHHCCEEEECC	24.98	22199227
5727	Phosphorylation	DIIRHKDSMDELFSH EEEECCCCHHHHHCC	32.70	101544975
5736	Phosphorylation	DELFSHRSEIFGTCG HHHHCCCHHHHCCCC	29.62	68695653
5741	Phosphorylation	HRSEIFGTCGEEQKT CCHHHHCCCCHHHHH	13.44	68695655
5808	Phosphorylation	ALIAQLPSPAIDHEQ HHHHCCCCCCCCHHH	35.24	30266825
5823	Phosphorylation	LRQQQEEMRQLRESI HHHHHHHHHHHHHHH	3.05	17081983
5857	Sulfoxidation	LNPEEGEMVEEKYQK CCHHCCHHHHHHHHH	7.27	21406390
5888	Phosphorylation	LALDEAVSQSTQITE HHHHHHHHHCCHHHH	26.01	24144214
5890	Phosphorylation	LDEAVSQSTQITEFH HHHHHHHCCHHHHHH	18.12	24144214
5891	Phosphorylation	DEAVSQSTQITEFHD HHHHHHCCHHHHHHH	19.16	24144214
5894	Phosphorylation	VSQSTQITEFHDKIE HHHCCHHHHHHHHHH	23.84	24144214
5906	Phosphorylation	KIEPMLETLENLSSR HHHHHHHHHHHHHHH	35.10	20068231
5911	Phosphorylation	LETLENLSSRLRMPP HHHHHHHHHHCCCCC	25.62	101544983
5912	Phosphorylation	ETLENLSSRLRMPPL HHHHHHHHHCCCCCC	38.20	20068231
6032	Phosphorylation	DIVHDLESPGIDPSI HHHHHCCCCCCCHHH	35.41	26657352
6038	Phosphorylation	ESPGIDPSIIKQQVE CCCCCCHHHHHHHHH	32.95	24719451
6080	Acetylation	FACGETEKPEVRKSI EECCCCCCHHHHHHH	54.63	26822725
6139	Sulfoxidation	TVIKLCTMPPVGTDL CCHHHHCCCCCCCCH	3.26	21406390
6160	Methylation	LNEMKEFKVEVYQQQ HHHHHHHHHHHHHHH	38.28	23644510
6180	Sulfoxidation	LNHQGELMLKKATDE CCCCCCCCCEECCCC	4.48	21406390
6210	2-Hydroxyisobutyrylation	LWENLGEKIAHRQHK HHHHHHHHHHHCHHH	43.31	-
6210	Acetylation	LWENLGEKIAHRQHK HHHHHHHHHHHCHHH	43.31	19608861
6210	Malonylation	LWENLGEKIAHRQHK HHHHHHHHHHHCHHH	43.31	26320211
6279	Phosphorylation	DVLAHQATVETVNKA CHHHHHCHHHHHHHH	16.59	28857561
6282	Phosphorylation	AHQATVETVNKAGNE HHHCHHHHHHHHHHH	25.66	68735289
6293	Phosphorylation	AGNELLESSAGDDAS HHHHHHHCCCCCCHH	26.00	68735295
6300	Phosphorylation	SSAGDDASSLRSRLE CCCCCCHHHHHHHHH	36.58	68735301
6353	Phosphorylation	LELTRMESQLSASKP HHHHHHHHHHHCCCC	27.38	76976243
6367	Phosphorylation	PTGGLPETAREQLDT CCCCCCHHHHHHHHH	29.13	28655764
6402	Phosphorylation	KGRLMLLSRDDSGSG HCCEEEEECCCCCCC	29.69	20068231
6406	Phosphorylation	MLLSRDDSGSGSKTE EEEECCCCCCCCCCH	38.86	20068231
6408	Phosphorylation	LSRDDSGSGSKTEQS EECCCCCCCCCCHHH	43.79	20068231
6410	Phosphorylation	RDDSGSGSKTEQSVA CCCCCCCCCCHHHHH	37.79	20068231
6412	Phosphorylation	DSGSGSKTEQSVALL CCCCCCCCHHHHHHH	40.74	46157659
6505	Phosphorylation	QIIELDQTGNQLKFL HHEEECCCCCHHHHC	37.45	46157665
6510	Acetylation	DQTGNQLKFLSQKQD CCCCCHHHHCCCCCC	34.20	26051181
6554	Acetylation	DDARKRAKQFHEAWK HHHHHHHHHHHHHHH	58.49	7962789
6600	Phosphorylation	KHKEFQKTLGGKQPV HCHHHHHHHCCCCCC	21.61	28857561
6604	Methylation	FQKTLGGKQPVYDTT HHHHHCCCCCCCCCC	50.02	-
6608	Phosphorylation	LGGKQPVYDTTIRTG HCCCCCCCCCCHHCC	17.79	20560465
6709	Acetylation	DAHKVFQKELGKRTG HHHHHHHHHHHCCCC	43.36	27452117
6715	O-linked_Glycosylation	QKELGKRTGTVQVLK HHHHHCCCCHHHHHC	40.46	30379171
6715	Phosphorylation	QKELGKRTGTVQVLK HHHHHCCCCHHHHHC	40.46	22331935
6717	O-linked_Glycosylation	ELGKRTGTVQVLKRS HHHCCCCHHHHHCCC	13.73	30379171
6717	Phosphorylation	ELGKRTGTVQVLKRS HHHCCCCHHHHHCCC	13.73	22210691
6724	Phosphorylation	TVQVLKRSGRELIEN HHHHHCCCCCHHHHC	40.38	22331941
6732	Phosphorylation	GRELIENSRDDTTWV CCHHHHCCCCCCHHH	25.05	50563171
6747	Phosphorylation	KGQLQELSTRWDTVC HHHHHHHHHHHHHHH	18.38	23403867
6757	Phosphorylation	WDTVCKLSVSKQSRL HHHHHHHCCCHHHHH	15.16	24719451
6777	O-linked_Glycosylation	QAEVFRDTVHMLLEW HHHHHHHHHHHHHHH	14.19	30379171
6786	O-linked_Glycosylation	HMLLEWLSEAEQTLR HHHHHHHHHHHHHHH	35.51	30379171
6791	O-linked_Glycosylation	WLSEAEQTLRFRGAL HHHHHHHHHHHCCCC	16.06	30379171
6944	Phosphorylation	VDRVTKTYKRKNIEP HHHHHHHCCCCCCCC	15.45	7319155
6952	Phosphorylation	KRKNIEPTHAPFIEK CCCCCCCCCCCCCCC	20.20	46157671
6960	Phosphorylation	HAPFIEKSRSGGRKS CCCCCCCCCCCCCCC	20.91	46157633
6962	Phosphorylation	PFIEKSRSGGRKSLS CCCCCCCCCCCCCCC	53.33	22817900
6967	Phosphorylation	SRSGGRKSLSQPTPP CCCCCCCCCCCCCCC	31.71	30266825
6969	Phosphorylation	SGGRKSLSQPTPPPM CCCCCCCCCCCCCCC	41.00	30266825
6972	Phosphorylation	RKSLSQPTPPPMPIL CCCCCCCCCCCCCCC	40.57	23927012
7016	Methylation	KLNDALDRLEELKEF HHHHHHHHHHHHHHH	44.86	-
7035	Phosphorylation	FDVWRKKYMRWMNHK HHHHHHHHHHHHHHH	8.57	27762562
7083	Phosphorylation	PTTKLEMTAVADIFD CCCCCEEEEEECCCC	14.49	16097034
7117	Phosphorylation	KDAYRPTTDADKIED CCCCCCCCCHHHHHH	31.69	28857561
7148	Malonylation	VEQIGENKYRFGDSQ EEEECCCCCCCCCHH	33.24	26320211
7209	Phosphorylation	FILPEGASQGMTPFR CCCCCCCCCCCCCCC	37.82	22199227
7212	Sulfoxidation	PEGASQGMTPFRSRG CCCCCCCCCCCCCCC	3.14	21406390
7213	Phosphorylation	EGASQGMTPFRSRGR CCCCCCCCCCCCCCC	26.54	25159151
7217	Phosphorylation	QGMTPFRSRGRRSKP CCCCCCCCCCCCCCC	39.19	22199227
7222	O-linked_Glycosylation	FRSRGRRSKPSSRAA CCCCCCCCCCCCCCC	47.78	30379171
7222	Phosphorylation	FRSRGRRSKPSSRAA CCCCCCCCCCCCCCC	47.78	30576142
7225	O-linked_Glycosylation	RGRRSKPSSRAASPT CCCCCCCCCCCCCCC	35.87	30379171
7225	Phosphorylation	RGRRSKPSSRAASPT CCCCCCCCCCCCCCC	35.87	30576142
7226	Phosphorylation	GRRSKPSSRAASPTR CCCCCCCCCCCCCCC	34.17	23312004
7230	Phosphorylation	KPSSRAASPTRSSSS CCCCCCCCCCCCCCC	26.31	30576142
7232	Phosphorylation	SSRAASPTRSSSSAS CCCCCCCCCCCCCCC	40.46	26329039
7234	Phosphorylation	RAASPTRSSSSASQS CCCCCCCCCCCCCCC	36.73	23927012
7235	Phosphorylation	AASPTRSSSSASQSN CCCCCCCCCCCCCCC	25.64	23403867
7236	Phosphorylation	ASPTRSSSSASQSNH CCCCCCCCCCCCCCC	31.04	23403867
7237	Phosphorylation	SPTRSSSSASQSNHS CCCCCCCCCCCCCCC	33.61	23401153
7239	Phosphorylation	TRSSSSASQSNHSCT CCCCCCCCCCCCCCC	35.77	23927012
7241	Phosphorylation	SSSSASQSNHSCTSM CCCCCCCCCCCCCCC	33.73	23403867
7244	Phosphorylation	SASQSNHSCTSMPSS CCCCCCCCCCCCCCC	24.28	23403867
7246	Phosphorylation	SQSNHSCTSMPSSPA CCCCCCCCCCCCCCC	30.95	23403867
7247	Phosphorylation	QSNHSCTSMPSSPAT CCCCCCCCCCCCCCC	32.78	23927012
7250	Phosphorylation	HSCTSMPSSPATPAS CCCCCCCCCCCCCCC	40.07	23403867
7251	Phosphorylation	SCTSMPSSPATPASG CCCCCCCCCCCCCCC	16.81	23927012
7254	Phosphorylation	SMPSSPATPASGTKV CCCCCCCCCCCCCEE	23.83	23927012
7257	Phosphorylation	SSPATPASGTKVIPS CCCCCCCCCCEEECC	48.47	23403867
7259	Phosphorylation	PATPASGTKVIPSSG CCCCCCCCEEECCCC	21.46	23403867
7264	Phosphorylation	SGTKVIPSSGSKLKR CCCEEECCCCCCCCC	35.89	24719451
7265	Phosphorylation	GTKVIPSSGSKLKRP CCEEECCCCCCCCCC	41.55	28348404
7267	Phosphorylation	KVIPSSGSKLKRPTP EEECCCCCCCCCCCC	36.44	28857561
7273	Phosphorylation	GSKLKRPTPTFHSSR CCCCCCCCCCCCCCC	38.71	23927012
7275	Phosphorylation	KLKRPTPTFHSSRTS CCCCCCCCCCCCCCC	36.14	23403867
7278	Phosphorylation	RPTPTFHSSRTSLAG CCCCCCCCCCCCCCC	19.82	23401153
7279	Phosphorylation	PTPTFHSSRTSLAGD CCCCCCCCCCCCCCC	30.89	29255136
7281	Phosphorylation	PTFHSSRTSLAGDTS CCCCCCCCCCCCCCC	30.00	23927012
7282	Phosphorylation	TFHSSRTSLAGDTSN CCCCCCCCCCCCCCC	18.34	23927012
7287	Phosphorylation	RTSLAGDTSNSSSPA CCCCCCCCCCCCCCC	28.96	23927012
7288	Phosphorylation	TSLAGDTSNSSSPAS CCCCCCCCCCCCCCC	39.18	6145855
7290	Phosphorylation	LAGDTSNSSSPASTG CCCCCCCCCCCCCCC	31.77	23927012
7291	Phosphorylation	AGDTSNSSSPASTGA CCCCCCCCCCCCCCC	44.59	23927012
7292	Phosphorylation	GDTSNSSSPASTGAK CCCCCCCCCCCCCCC	25.06	25159151
7295	Phosphorylation	SNSSSPASTGAKTNR CCCCCCCCCCCCCCC	30.66	25159151
7296	Phosphorylation	NSSSPASTGAKTNRA CCCCCCCCCCCCCCC	43.17	6144615
7308	Phosphorylation	NRADPKKSASRPGSR CCCCCCCCCCCCCCC	37.29	24719451
7310	Phosphorylation	ADPKKSASRPGSRAG CCCCCCCCCCCCCCC	46.21	37013849
7314	Phosphorylation	KSASRPGSRAGSRAG CCCCCCCCCCCCCCC	22.95	30854055
7318	Phosphorylation	RPGSRAGSRAGSRAS CCCCCCCCCCCCCCC	20.26	37013851
7322	Phosphorylation	RAGSRAGSRASSRRG CCCCCCCCCCCCCCC	24.56	37013847
7325	Phosphorylation	SRAGSRASSRRGSDA CCCCCCCCCCCCCCC	24.22	23927012
7326	Phosphorylation	RAGSRASSRRGSDAS CCCCCCCCCCCCCCH	25.63	37013853
7330	Phosphorylation	RASSRRGSDASDFDL CCCCCCCCCCHHCHH	28.35	22167270
7333	Phosphorylation	SRRGSDASDFDLLET CCCCCCCHHCHHCHH	43.74	30266825
7340	Phosphorylation	SDFDLLETQSACSDT HHCHHCHHCCCCCCC	28.00	30266825
7342	Phosphorylation	FDLLETQSACSDTSE CHHCHHCCCCCCCCH	38.37	30266825
7345	Phosphorylation	LETQSACSDTSESSA CHHCCCCCCCCHHHC	43.57	30266825
7347	Phosphorylation	TQSACSDTSESSAAG HCCCCCCCCHHHCCC	20.35	30266825
7348	Phosphorylation	QSACSDTSESSAAGG CCCCCCCCHHHCCCC	40.24	30266825
7350	Phosphorylation	ACSDTSESSAAGGQG CCCCCCHHHCCCCCC	25.66	30266825
7351	Phosphorylation	CSDTSESSAAGGQGN CCCCCHHHCCCCCCC	20.34	30266825
7359	Phosphorylation	AAGGQGNSRRGLNKP CCCCCCCCCCCCCCC	30.13	23927012
7361	Methylation	GGQGNSRRGLNKPSK CCCCCCCCCCCCCCC	54.49	-
7373	Phosphorylation	PSKIPTMSKKTTTAS CCCCCCCCCCCCCCC	33.22	28857561
7375	Methylation	KIPTMSKKTTTASPR CCCCCCCCCCCCCCC	43.74	-
7376	Phosphorylation	IPTMSKKTTTASPRT CCCCCCCCCCCCCCC	32.87	22199227
7377	Phosphorylation	PTMSKKTTTASPRTP CCCCCCCCCCCCCCC	29.28	22199227
7378	Phosphorylation	TMSKKTTTASPRTPG CCCCCCCCCCCCCCC	30.30	22199227
7380	Phosphorylation	SKKTTTASPRTPGPK CCCCCCCCCCCCCCC	16.90	30576142
7383	Phosphorylation	TTTASPRTPGPKR-- CCCCCCCCCCCCC--	35.66	23403867

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
7213	T	Phosphorylation	Kinase	CDK2	P24941	PSP
7222	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7226	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7230	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7234	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7310	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7314	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7318	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7322	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7326	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
7330	S	Phosphorylation	Kinase	GSK3B	P49841	PSP

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MACF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MACF1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PSMD5_HUMAN	PSMD5	physical	22939629
PDIA6_HUMAN	PDIA6	physical	22939629
YBOX3_HUMAN	YBX3	physical	22863883

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-6210, AND MASS SPECTROMETRY.
PubMed: 19608861

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1376; SER-4521 ANDSER-7330, AND MASS SPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4521; SER-7288; SER-7290AND SER-7292, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-280; SER-1376; SER-3927;SER-4495; SER-4496; SER-4521; SER-6967; SER-7247; SER-7251; THR-7254;SER-7292 AND SER-7330, AND MASS SPECTROMETRY.
PubMed: 18669648

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4521, AND MASSSPECTROMETRY.
PubMed: 18187866

"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry.";
Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4141; SER-4142 ANDSER-4144, AND MASS SPECTROMETRY.
PubMed: 17287340

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-3927; SER-4521 ANDTHR-7273, AND MASS SPECTROMETRY.
PubMed: 17081983

"Global phosphoproteome analysis on human HepG2 hepatocytes usingreversed-phase diagonal LC.";
Gevaert K., Staes A., Van Damme J., De Groot S., Hugelier K.,Demol H., Martens L., Goethals M., Vandekerckhove J.;
Proteomics 5:3589-3599(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-7083, AND MASSSPECTROMETRY.
PubMed: 16097034

"Tyrosine phosphorylated Par3 regulates epithelial tight junctionassembly promoted by EGFR signaling.";
Wang Y., Du D., Fang L., Yang G., Zhang C., Zeng R., Ullrich A.,Lottspeich F., Chen Z.;
EMBO J. 25:5058-5070(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-3119, AND MASSSPECTROMETRY.
PubMed: 17053785