| UniProt ID | UBP15_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y4E8 | |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 15 | |
| Gene Name | USP15 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 981 | |
| Subcellular Localization | Cytoplasm . Nucleus . Mitochondrion . | |
| Protein Description | Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling, NF-kappa-B and RNF41/NRDP1-PRKN pathways. [PubMed: 21947082] | |
| Protein Sequence | MAEGGAADLDTQRSDIATLLKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQNVYPGPIDNSGLLKDGDAQSLKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKVVEQGMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKADTIDTIEKEIRKIFSIPDEKETRLWNKYMSNTFEPLNKPDSTIQDAGLYQGQVLVIEQKNEDGTWPRGPSTPKSPGASNFSTLPKISPSSLSNNYNNMNNRNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLEVYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYNHRFHRIFAMDENLSSIMERDDIYVFEININRTEDTEHVIIPVCLREKFRHSSYTHHTGSSLFGQPFLMAVPRNNTEDKLYNLLLLRMCRYVKISTETEETEGSLHCCKDQNINGNGPNGIHEEGSPSEMETDEPDDESSQDQELPSENENSQSEDSVGGDNDSENGLCTEDTCKGQLTGHKKRLFTFQFNNLGNTDINYIKDDTRHIRFDDRQLRLDERSFLALDWDPDLKKRYFDENAAEDFEKHESVEYKPPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGFFPLDRETKGASAATGIPLESDEDSNDNDNDIENENCMHTN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAEGGAADL ------CCCCCCCCC | 24.92 | 22223895 | |
| 11 | Phosphorylation | GGAADLDTQRSDIAT CCCCCCCCCHHHHHH | 32.93 | 28348404 | |
| 14 | Phosphorylation | ADLDTQRSDIATLLK CCCCCCHHHHHHHHH | 24.45 | 28348404 | |
| 14 | Ubiquitination | ADLDTQRSDIATLLK CCCCCCHHHHHHHHH | 24.45 | 23000965 | |
| 20 | Ubiquitination | RSDIATLLKTSLRKG HHHHHHHHHHHHCCC | 5.03 | 21890473 | |
| 21 | Ubiquitination | SDIATLLKTSLRKGD HHHHHHHHHHHCCCC | 38.90 | 29967540 | |
| 22 | Phosphorylation | DIATLLKTSLRKGDT HHHHHHHHHHCCCCE | 32.72 | 23312004 | |
| 23 | Phosphorylation | IATLLKTSLRKGDTW HHHHHHHHHCCCCEE | 25.29 | 23312004 | |
| 33 | Ubiquitination | KGDTWYLVDSRWFKQ CCCEEEEECHHHHHH | 3.54 | 21890473 | |
| 42 | Ubiquitination | SRWFKQWKKYVGFDS HHHHHHHHHHCCCCC | 31.56 | 24816145 | |
| 46 | Ubiquitination | KQWKKYVGFDSWDKY HHHHHHCCCCCCCCC | 19.97 | 24816145 | |
| 49 | Phosphorylation | KKYVGFDSWDKYQMG HHHCCCCCCCCCCCC | 34.61 | 28348404 | |
| 61 | Ubiquitination | QMGDQNVYPGPIDNS CCCCCCCCCCCCCCC | 15.26 | 22817900 | |
| 78 | Phosphorylation | LKDGDAQSLKEHLID CCCCCHHHHHHHHHH | 43.03 | 28060719 | |
| 89 | Phosphorylation | HLIDELDYILLPTEG HHHHHCCEEEECCCH | 13.19 | - | |
| 102 | Phosphorylation | EGWNKLVSWYTLMEG CHHHHHHHHHHHHCC | 25.46 | 20068231 | |
| 104 | Phosphorylation | WNKLVSWYTLMEGQE HHHHHHHHHHHCCCC | 5.19 | 20068231 | |
| 105 | Phosphorylation | NKLVSWYTLMEGQEP HHHHHHHHHHCCCCC | 17.23 | 20068231 | |
| 107 | Ubiquitination | LVSWYTLMEGQEPIA HHHHHHHHCCCCCHH | 4.13 | 21890473 | |
| 108 | Phosphorylation | VSWYTLMEGQEPIAR HHHHHHHCCCCCHHH | 61.92 | 32645325 | |
| 122 | Sulfoxidation | RKVVEQGMFVKHCKV HHHHHCCCEEEECEE | 3.31 | 21406390 | |
| 134 | Phosphorylation | CKVEVYLTELKLCEN CEEEEEEEEEEEECC | 22.91 | 25627689 | |
| 138 | Ubiquitination | VYLTELKLCENGNMN EEEEEEEEECCCCCC | 7.47 | 23000965 | |
| 149 | Phosphorylation | GNMNNVVTRRFSKAD CCCCCCEEECCCCCC | 16.31 | - | |
| 151 | Ubiquitination | MNNVVTRRFSKADTI CCCCEEECCCCCCCH | 30.72 | 21963094 | |
| 154 | Ubiquitination | VVTRRFSKADTIDTI CEEECCCCCCCHHHH | 47.79 | 21890473 | |
| 154 | Ubiquitination | VVTRRFSKADTIDTI CEEECCCCCCCHHHH | 47.79 | 21890473 | |
| 154 | Acetylation | VVTRRFSKADTIDTI CEEECCCCCCCHHHH | 47.79 | 26051181 | |
| 154 | Ubiquitination | VVTRRFSKADTIDTI CEEECCCCCCCHHHH | 47.79 | 22817900 | |
| 154 (in isoform 1) | Ubiquitination | - | 47.79 | 21890473 | |
| 154 (in isoform 2) | Ubiquitination | - | 47.79 | 21890473 | |
| 154 (in isoform 3) | Ubiquitination | - | 47.79 | 21890473 | |
| 160 | Phosphorylation | SKADTIDTIEKEIRK CCCCCHHHHHHHHHH | 27.47 | 28674419 | |
| 163 | Ubiquitination | DTIDTIEKEIRKIFS CCHHHHHHHHHHHHC | 55.37 | 24816145 | |
| 167 | Ubiquitination | TIEKEIRKIFSIPDE HHHHHHHHHHCCCCH | 54.48 | 24816145 | |
| 170 | Phosphorylation | KEIRKIFSIPDEKET HHHHHHHCCCCHHHH | 36.36 | 21815630 | |
| 175 | Ubiquitination | IFSIPDEKETRLWNK HHCCCCHHHHHHHHH | 72.30 | 29967540 | |
| 182 | Ubiquitination | KETRLWNKYMSNTFE HHHHHHHHHHCCCCC | 30.65 | 22817900 | |
| 183 | Phosphorylation | ETRLWNKYMSNTFEP HHHHHHHHHCCCCCC | 11.54 | 22468782 | |
| 185 | Phosphorylation | RLWNKYMSNTFEPLN HHHHHHHCCCCCCCC | 29.63 | 22468782 | |
| 187 | Phosphorylation | WNKYMSNTFEPLNKP HHHHHCCCCCCCCCC | 23.28 | 27251275 | |
| 193 | Ubiquitination | NTFEPLNKPDSTIQD CCCCCCCCCCCCCCC | 58.86 | 29967540 | |
| 219 | Phosphorylation | EQKNEDGTWPRGPST EEECCCCCCCCCCCC | 44.62 | 30576142 | |
| 219 (in isoform 2) | Phosphorylation | - | 44.62 | 22199227 | |
| 223 (in isoform 3) | Phosphorylation | - | 19.21 | 22199227 | |
| 225 | Phosphorylation | GTWPRGPSTPKSPGA CCCCCCCCCCCCCCC | 61.23 | 23927012 | |
| 225 (in isoform 2) | Phosphorylation | - | 61.23 | 22199227 | |
| 225 (in isoform 4) | Phosphorylation | - | 61.23 | 25849741 | |
| 226 | Phosphorylation | TWPRGPSTPKSPGAS CCCCCCCCCCCCCCC | 37.56 | 25159151 | |
| 226 | Ubiquitination | TWPRGPSTPKSPGAS CCCCCCCCCCCCCCC | 37.56 | 23000965 | |
| 226 (in isoform 2) | Phosphorylation | - | 37.56 | 22199227 | |
| 226 (in isoform 4) | Phosphorylation | - | 37.56 | 22617229 | |
| 228 | Ubiquitination | PRGPSTPKSPGASNF CCCCCCCCCCCCCCC | 70.17 | 21890473 | |
| 228 | Ubiquitination | PRGPSTPKSPGASNF CCCCCCCCCCCCCCC | 70.17 | 22817900 | |
| 228 (in isoform 1) | Ubiquitination | - | 70.17 | 21890473 | |
| 229 | Phosphorylation | RGPSTPKSPGASNFS CCCCCCCCCCCCCCC | 29.75 | 19664994 | |
| 229 (in isoform 3) | Phosphorylation | - | 29.75 | 22199227 | |
| 230 | Ubiquitination | GPSTPKSPGASNFST CCCCCCCCCCCCCCC | 48.79 | 23000965 | |
| 230 (in isoform 3) | Phosphorylation | - | 48.79 | 22199227 | |
| 232 | Ubiquitination | STPKSPGASNFSTLP CCCCCCCCCCCCCCC | 12.51 | 21890473 | |
| 233 | Phosphorylation | TPKSPGASNFSTLPK CCCCCCCCCCCCCCC | 44.30 | 30266825 | |
| 234 (in isoform 2) | Phosphorylation | - | 34.06 | 25159151 | |
| 234 (in isoform 4) | Phosphorylation | - | 34.06 | 27251275 | |
| 236 | Phosphorylation | SPGASNFSTLPKISP CCCCCCCCCCCCCCH | 33.03 | 26846344 | |
| 237 | Phosphorylation | PGASNFSTLPKISPS CCCCCCCCCCCCCHH | 42.83 | 26846344 | |
| 238 (in isoform 3) | Phosphorylation | - | 3.84 | 25159151 | |
| 242 | Phosphorylation | FSTLPKISPSSLSNN CCCCCCCCHHHCCCC | 25.51 | 21945579 | |
| 243 | Ubiquitination | STLPKISPSSLSNNY CCCCCCCHHHCCCCC | 31.26 | 21963094 | |
| 244 | Phosphorylation | TLPKISPSSLSNNYN CCCCCCHHHCCCCCC | 36.80 | 23401153 | |
| 245 | Phosphorylation | LPKISPSSLSNNYNN CCCCCHHHCCCCCCC | 38.92 | 21945579 | |
| 247 | Phosphorylation | KISPSSLSNNYNNMN CCCHHHCCCCCCCCC | 25.61 | 21945579 | |
| 250 | Phosphorylation | PSSLSNNYNNMNNRN HHHCCCCCCCCCCCC | 16.50 | 21945579 | |
| 259 | Methylation | NMNNRNVKNSNYCLP CCCCCCCCCCCCCCC | 59.20 | 54429133 | |
| 259 | Ubiquitination | NMNNRNVKNSNYCLP CCCCCCCCCCCCCCC | 59.20 | 23000965 | |
| 261 | Phosphorylation | NNRNVKNSNYCLPSY CCCCCCCCCCCCCCC | 24.37 | 21945579 | |
| 263 | Phosphorylation | RNVKNSNYCLPSYTA CCCCCCCCCCCCCCE | 8.66 | 21945579 | |
| 267 | Phosphorylation | NSNYCLPSYTAYKNY CCCCCCCCCCEECCC | 23.36 | 28555341 | |
| 268 | Phosphorylation | SNYCLPSYTAYKNYD CCCCCCCCCEECCCC | 8.08 | 21945579 | |
| 269 | Phosphorylation | NYCLPSYTAYKNYDY CCCCCCCCEECCCCC | 28.05 | 28442448 | |
| 271 | Phosphorylation | CLPSYTAYKNYDYSE CCCCCCEECCCCCCC | 7.62 | 28442448 | |
| 272 | Ubiquitination | LPSYTAYKNYDYSEP CCCCCEECCCCCCCC | 46.71 | 23000965 | |
| 274 | Phosphorylation | SYTAYKNYDYSEPGR CCCEECCCCCCCCCC | 16.47 | 28796482 | |
| 276 | Phosphorylation | TAYKNYDYSEPGRNN CEECCCCCCCCCCCC | 12.46 | 28796482 | |
| 277 | Phosphorylation | AYKNYDYSEPGRNNE EECCCCCCCCCCCCC | 34.12 | 28442448 | |
| 311 | Ubiquitination | IQCLSNTPPLTEYFL HHHHHCCCCCHHHHH | 26.59 | 29967540 | |
| 318 | Ubiquitination | PPLTEYFLNDKYQEE CCCHHHHHCHHHHHH | 8.74 | 23000965 | |
| 324 | Ubiquitination | FLNDKYQEELNFDNP HHCHHHHHHHCCCCC | 62.45 | 21890473 | |
| 324 (in isoform 2) | Ubiquitination | - | 62.45 | 21890473 | |
| 329 (in isoform 3) | Ubiquitination | - | 55.56 | 21890473 | |
| 340 | Ubiquitination | GMRGEIAKSYAELIK CHHHHHHHHHHHHHH | 50.05 | 29967540 | |
| 347 | Ubiquitination | KSYAELIKQMWSGKF HHHHHHHHHHHCCCC | 46.88 | 23000965 | |
| 353 | Ubiquitination | IKQMWSGKFSYVTPR HHHHHCCCCCEECCH | 26.14 | 21890473 | |
| 353 | Ubiquitination | IKQMWSGKFSYVTPR HHHHHCCCCCEECCH | 26.14 | 23000965 | |
| 353 (in isoform 1) | Ubiquitination | - | 26.14 | 21890473 | |
| 355 | Phosphorylation | QMWSGKFSYVTPRAF HHHCCCCCEECCHHH | 23.37 | 25348954 | |
| 356 | Phosphorylation | MWSGKFSYVTPRAFK HHCCCCCEECCHHHH | 16.10 | 25348954 | |
| 358 | Phosphorylation | SGKFSYVTPRAFKTQ CCCCCEECCHHHHHC | 9.99 | 25348954 | |
| 363 | Methylation | YVTPRAFKTQVGRFA EECCHHHHHCCCCCC | 36.74 | 54429125 | |
| 363 | Ubiquitination | YVTPRAFKTQVGRFA EECCHHHHHCCCCCC | 36.74 | - | |
| 373 | Ubiquitination | VGRFAPQFSGYQQQD CCCCCCCCCCCCHHH | 6.27 | 29967540 | |
| 379 | Ubiquitination | QFSGYQQQDCQELLA CCCCCCHHHHHHHHH | 37.61 | 29967540 | |
| 387 | Ubiquitination | DCQELLAFLLDGLHE HHHHHHHHHHHHHHH | 7.60 | 29967540 | |
| 402 | Ubiquitination | DLNRIRKKPYIQLKD HHHHHHCCCCEECCC | 32.95 | 29967540 | |
| 408 | Ubiquitination | KKPYIQLKDADGRPD CCCCEECCCCCCCCC | 34.20 | 29967540 | |
| 416 | Ubiquitination | DADGRPDKVVAEEAW CCCCCCCCCHHHHHH | 41.09 | 29967540 | |
| 445 | Phosphorylation | FHGLFKSTLVCPECA CCCHHHCCCCCCCHH | 24.65 | - | |
| 446 | Ubiquitination | HGLFKSTLVCPECAK CCHHHCCCCCCCHHE | 4.88 | 33845483 | |
| 475 | Phosphorylation | LPMKKERTLEVYLVR CCCCCCCEEEEEEEE | 28.50 | 30622161 | |
| 479 | Phosphorylation | KERTLEVYLVRMDPL CCCEEEEEEEECCCC | 7.07 | 30622161 | |
| 480 | Ubiquitination | ERTLEVYLVRMDPLT CCEEEEEEEECCCCC | 2.08 | 23000965 | |
| 484 | Ubiquitination | EVYLVRMDPLTKPMQ EEEEEECCCCCCCCE | 25.21 | 21890473 | |
| 487 | Phosphorylation | LVRMDPLTKPMQYKV EEECCCCCCCCEEEE | 38.19 | 24850871 | |
| 492 | Phosphorylation | PLTKPMQYKVVVPKI CCCCCCEEEEEECCC | 10.25 | 30622161 | |
| 530 | Ubiquitination | TDIYNHRFHRIFAMD EECHHCCCHHEEEEC | 3.36 | 33845483 | |
| 564 | Ubiquitination | NRTEDTEHVIIPVCL ECCCCCCEEEEEHHH | 20.40 | 33845483 | |
| 576 | Ubiquitination | VCLREKFRHSSYTHH HHHHHHHCCCCCCCC | 39.59 | 21890473 | |
| 576 (in isoform 2) | Ubiquitination | - | 39.59 | 21890473 | |
| 578 | Phosphorylation | LREKFRHSSYTHHTG HHHHHCCCCCCCCCC | 22.30 | 21406692 | |
| 579 | Phosphorylation | REKFRHSSYTHHTGS HHHHCCCCCCCCCCC | 28.11 | 21406692 | |
| 580 | Phosphorylation | EKFRHSSYTHHTGSS HHHCCCCCCCCCCCC | 17.07 | 21406692 | |
| 581 | Phosphorylation | KFRHSSYTHHTGSSL HHCCCCCCCCCCCCC | 14.77 | 21406692 | |
| 581 (in isoform 3) | Ubiquitination | - | 14.77 | 21890473 | |
| 584 | Phosphorylation | HSSYTHHTGSSLFGQ CCCCCCCCCCCCCCC | 31.02 | 21406692 | |
| 586 | Phosphorylation | SYTHHTGSSLFGQPF CCCCCCCCCCCCCCE | 25.64 | 21406692 | |
| 587 | Phosphorylation | YTHHTGSSLFGQPFL CCCCCCCCCCCCCEE | 29.12 | 21406692 | |
| 602 | Phosphorylation | MAVPRNNTEDKLYNL EEECCCCCHHHHHHH | 49.46 | 20068231 | |
| 605 | Ubiquitination | PRNNTEDKLYNLLLL CCCCCHHHHHHHHHH | 46.79 | 21890473 | |
| 605 | Ubiquitination | PRNNTEDKLYNLLLL CCCCCHHHHHHHHHH | 46.79 | 23000965 | |
| 605 (in isoform 1) | Ubiquitination | - | 46.79 | 21890473 | |
| 607 | Phosphorylation | NNTEDKLYNLLLLRM CCCHHHHHHHHHHHH | 14.98 | 20068231 | |
| 621 | Phosphorylation | MCRYVKISTETEETE HHCEEECCCCCCCCC | 17.93 | 23312004 | |
| 622 | Phosphorylation | CRYVKISTETEETEG HCEEECCCCCCCCCC | 50.85 | 23312004 | |
| 624 | Phosphorylation | YVKISTETEETEGSL EEECCCCCCCCCCCE | 38.93 | 23312004 | |
| 627 | Phosphorylation | ISTETEETEGSLHCC CCCCCCCCCCCEEEE | 39.14 | 24719451 | |
| 630 | Phosphorylation | ETEETEGSLHCCKDQ CCCCCCCCEEEECCC | 14.54 | 25849741 | |
| 632 | Phosphorylation | EETEGSLHCCKDQNI CCCCCCEEEECCCCC | 19.34 | 33259812 | |
| 658 | Ubiquitination | GSPSEMETDEPDDES CCCCCCCCCCCCCCC | 44.33 | 33845483 | |
| 678 | Phosphorylation | LPSENENSQSEDSVG CCCCCCCCCCCCCCC | 28.98 | 17478428 | |
| 692 | Ubiquitination | GGDNDSENGLCTEDT CCCCCCCCCEECCCC | 53.33 | 23000965 | |
| 716 | Phosphorylation | KRLFTFQFNNLGNTD CEEEEEEECCCCCCC | 5.98 | 33259812 | |
| 726 | Phosphorylation | LGNTDINYIKDDTRH CCCCCCEEECCCCCE | 15.07 | - | |
| 728 | Ubiquitination | NTDINYIKDDTRHIR CCCCEEECCCCCEEE | 38.91 | - | |
| 729 | Ubiquitination | TDINYIKDDTRHIRF CCCEEECCCCCEEEE | 53.61 | 29967540 | |
| 750 | Ubiquitination | LDERSFLALDWDPDL CCCCCEECCCCCHHH | 11.06 | 33845483 | |
| 753 | Ubiquitination | RSFLALDWDPDLKKR CCEECCCCCHHHHHH | 21.64 | 29967540 | |
| 754 | Ubiquitination | SFLALDWDPDLKKRY CEECCCCCHHHHHHH | 26.88 | 29967540 | |
| 758 | Acetylation | LDWDPDLKKRYFDEN CCCCHHHHHHHCCCC | 42.45 | 24471339 | |
| 758 | Ubiquitination | LDWDPDLKKRYFDEN CCCCHHHHHHHCCCC | 42.45 | 29967540 | |
| 759 | Acetylation | DWDPDLKKRYFDENA CCCHHHHHHHCCCCC | 60.68 | 24469783 | |
| 760 | Ubiquitination | WDPDLKKRYFDENAA CCHHHHHHHCCCCCH | 35.45 | 29967540 | |
| 769 | Ubiquitination | FDENAAEDFEKHESV CCCCCHHHHHHCCCC | 52.88 | 29967540 | |
| 779 | Ubiquitination | KHESVEYKPPKKPFV HCCCCCCCCCCCCCE | 41.14 | 33845483 | |
| 782 | Ubiquitination | SVEYKPPKKPFVKLK CCCCCCCCCCCEEHH | 79.98 | 29967540 | |
| 783 | Ubiquitination | VEYKPPKKPFVKLKD CCCCCCCCCCEEHHH | 49.84 | 29967540 | |
| 784 | Ubiquitination | EYKPPKKPFVKLKDC CCCCCCCCCEEHHHH | 45.44 | 23000965 | |
| 789 | Ubiquitination | KKPFVKLKDCIELFT CCCCEEHHHHHHHHH | 44.85 | 29967540 | |
| 798 | Ubiquitination | CIELFTTKEKLGAED HHHHHHCHHHHCCCC | 50.20 | 29967540 | |
| 813 | Ubiquitination | PWYCPNCKEHQQATK CCCCCCHHHHHHHHH | 65.94 | 23000965 | |
| 826 | Phosphorylation | TKKLDLWSLPPVLVV HHHCCHHHCCCEEEE | 37.99 | - | |
| 844 | Phosphorylation | RFSYSRYMRDKLDTL CCCHHHHHHHHHCCC | 4.31 | 33259812 | |
| 881 | Phosphorylation | RYNLIAVSNHYGGMG EEEEEEEECCCCCCC | 14.63 | - | |
| 926 | Phosphorylation | QIVSKAAYVLFYQRQ HHHCHHEEEEEEEEC | 11.53 | 28152594 | |
| 935 | Phosphorylation | LFYQRQDTFSGTGFF EEEEECCCCCCCCCE | 16.03 | 21406692 | |
| 936 | Phosphorylation | FYQRQDTFSGTGFFP EEEECCCCCCCCCEE | 9.49 | 33259812 | |
| 937 | Phosphorylation | YQRQDTFSGTGFFPL EEECCCCCCCCCEEC | 37.22 | 21406692 | |
| 939 | Phosphorylation | RQDTFSGTGFFPLDR ECCCCCCCCCEECCC | 29.62 | 21406692 | |
| 952 | Phosphorylation | DRETKGASAATGIPL CCCCCCCCCCCCCCC | 27.40 | 23927012 | |
| 955 | Phosphorylation | TKGASAATGIPLESD CCCCCCCCCCCCCCC | 35.05 | 30278072 | |
| 961 | Phosphorylation | ATGIPLESDEDSNDN CCCCCCCCCCCCCCC | 54.72 | 23927012 | |
| 965 | Phosphorylation | PLESDEDSNDNDNDI CCCCCCCCCCCCCCC | 43.99 | 23927012 | |
| 980 | Phosphorylation | ENENCMHTN------ CCCCCCCCC------ | 0.00 | 28450419 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UBP15_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UBP15_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Acetylation | |
| Reference | PubMed |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-229; SER-961 AND SER-965, AND MASSSPECTROMETRY. | |
| Phosphorylation | |
| Reference | PubMed |
| "Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-229, AND MASSSPECTROMETRY. | |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-229; SER-961 AND SER-965, AND MASSSPECTROMETRY. | |
| "A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-229; SER-961 ANDSER-965, AND MASS SPECTROMETRY. | |
| "A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-229, AND MASSSPECTROMETRY. | |
