dbPTM

ZMYM2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZMYM2_HUMAN
UniProt AC	Q9UBW7
Protein Name	Zinc finger MYM-type protein 2
Gene Name	ZMYM2
Organism	Homo sapiens (Human).
Sequence Length	1377
Subcellular Localization	Nucleus .
Protein Description	May function as a transcription factor..
Protein Sequence	MDTSSVGGLELTDQTPVLLGSTAMATSLTNVGNSFSGPANPLVSRSNKFQNSSVEDDDDVVFIEPVQPPPPSVPVVADQRTITFTSSKNEELQGNDSKITPSSKELASQKGSVSETIVIDDEEDMETNQGQEKNSSNFIERRPPETKNRTNDVDFSTSSFSRSKVNAGMGNSGITTEPDSEIQIANVTTLETGVSSVNDGQLENTDGRDMNLMITHVTSLQNTNLGDVSNGLQSSNFGVNIQTYTPSLTSQTKTGVGPFNPGRMNVAGDVFQNGESATHHNPDSWISQSASFPRNQKQPGVDSLSPVASLPKQIFQPSVQQQPTKPVKVTCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHKPAPKKLCVMCKKDITTMKGTIVAQVDSSESFQEFCSTSCLSLYEDKQNPTKGALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRMANGLIMNCCEQCGEYLPSKGAGNNVLVIDGQQKRFCCQSCVSEYKQVGSHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRFFDMTQCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFCNSSCVAKFQALSMQSSPNGQFVAPSDIQLKCNYCKNSFCSKPEILEWENKVHQFCSKTCSDDYKKLHCIVTYCEYCQEEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLGLRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQDWYYKAARCDCCKSQGTLKERVQWRGEMKHFCDQHCLLRFYCQQNEPNMTTQKGPENLHYDQGCQTSRTKMTGSAPPPSPTPNKEMKNKAVLCKPLTMTKATYCKPHMQTKSCQTDDTWRTEYVPVPIPVPVYIPVPMHMYSQNIPVPTTVPVPVPVPVFLPAPLDSSEKIPAAIEELKSKVSSDALDTELLTMTDMMSEDEGKTETTNINSVIIETDIIGSDLLKNSDPETQSSMPDVPYEPDLDIEIDFPRAAEELDMENEFLLPPVFGEEYEEQPRPRSKKKGAKRKAVSGYQSHDDSSDNSECSFPFKYTYGVNAWKHWVKTRQLDEDLLVLDELKSSKSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQTFEQELNKILRSWQPSILPDGSIFSRVEEDYLWRIKQLGSHSPVALLNTLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVSSLCGTDNEDKITTGKRKHEDDEPVFEQIENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSTSLDRNTLENMLVRVLLVKDIYDKDNYELDEDTD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Phosphorylation	ANPLVSRSNKFQNSS CCHHCCCCCCCCCCC	36.54	21712546
48	Sumoylation	PLVSRSNKFQNSSVE HHCCCCCCCCCCCCC	49.96	28112733
52	Phosphorylation	RSNKFQNSSVEDDDD CCCCCCCCCCCCCCC	25.61	21712546
53	Phosphorylation	SNKFQNSSVEDDDDV CCCCCCCCCCCCCCE	36.76	21712546
83	Phosphorylation	VADQRTITFTSSKNE EECCCEEEEECCCCH	21.90	26714015
85	Phosphorylation	DQRTITFTSSKNEEL CCCEEEEECCCCHHH	24.36	26714015
86	Phosphorylation	QRTITFTSSKNEELQ CCEEEEECCCCHHHC	34.81	26714015
87	Phosphorylation	RTITFTSSKNEELQG CEEEEECCCCHHHCC	36.12	26714015
88	Sumoylation	TITFTSSKNEELQGN EEEEECCCCHHHCCC	69.05	-
88	Sumoylation	TITFTSSKNEELQGN EEEEECCCCHHHCCC	69.05	28112733
88	Ubiquitination	TITFTSSKNEELQGN EEEEECCCCHHHCCC	69.05	-
98	Sumoylation	ELQGNDSKITPSSKE HHCCCCCCCCCCHHH	54.16	-
98	Sumoylation	ELQGNDSKITPSSKE HHCCCCCCCCCCHHH	54.16	28112733
98	Ubiquitination	ELQGNDSKITPSSKE HHCCCCCCCCCCHHH	54.16	-
104	Sumoylation	SKITPSSKELASQKG CCCCCCHHHHHHCCC	62.17	-
104	Acetylation	SKITPSSKELASQKG CCCCCCHHHHHHCCC	62.17	11921573
104	Sumoylation	SKITPSSKELASQKG CCCCCCHHHHHHCCC	62.17	28112733
104	Ubiquitination	SKITPSSKELASQKG CCCCCCHHHHHHCCC	62.17	-
108	Phosphorylation	PSSKELASQKGSVSE CCHHHHHHCCCCCCE	45.08	26074081
112	Phosphorylation	ELASQKGSVSETIVI HHHHCCCCCCEEEEE	29.52	26074081
114	Phosphorylation	ASQKGSVSETIVIDD HHCCCCCCEEEEECC	30.62	26074081
116	Phosphorylation	QKGSVSETIVIDDEE CCCCCCEEEEECCHH	17.03	26074081
127	Phosphorylation	DDEEDMETNQGQEKN CCHHHHCCCCCCCCC	26.63	26074081
136	Phosphorylation	QGQEKNSSNFIERRP CCCCCCCCCCCCCCC	45.19	28555341
147	Sumoylation	ERRPPETKNRTNDVD CCCCCCCCCCCCCCC	42.65	28112733
150	Phosphorylation	PPETKNRTNDVDFST CCCCCCCCCCCCCCC	45.20	25954137
156	Phosphorylation	RTNDVDFSTSSFSRS CCCCCCCCCHHCCHH	23.94	21406692
157	Phosphorylation	TNDVDFSTSSFSRSK CCCCCCCCHHCCHHH	28.52	21406692
158	Phosphorylation	NDVDFSTSSFSRSKV CCCCCCCHHCCHHHC	28.34	23401153
159	Phosphorylation	DVDFSTSSFSRSKVN CCCCCCHHCCHHHCC	27.59	23401153
161	Phosphorylation	DFSTSSFSRSKVNAG CCCCHHCCHHHCCCC	37.28	25954137
253	Sumoylation	PSLTSQTKTGVGPFN CCCCCCCCCCCCCCC	35.33	-
253	Sumoylation	PSLTSQTKTGVGPFN CCCCCCCCCCCCCCC	35.33	28112733
276	Phosphorylation	DVFQNGESATHHNPD CHHCCCCCCCCCCCC	39.61	28961369
289	Phosphorylation	PDSWISQSASFPRNQ CCCHHHCCCCCCCCC	21.06	28961369
291	Phosphorylation	SWISQSASFPRNQKQ CHHHCCCCCCCCCCC	40.82	28961369
297	Sumoylation	ASFPRNQKQPGVDSL CCCCCCCCCCCCCCC	63.11	-
297	Sumoylation	ASFPRNQKQPGVDSL CCCCCCCCCCCCCCC	63.11	28112733
297	Ubiquitination	ASFPRNQKQPGVDSL CCCCCCCCCCCCCCC	63.11	-
303	Phosphorylation	QKQPGVDSLSPVASL CCCCCCCCCCCCCCC	28.48	30266825
305	Phosphorylation	QPGVDSLSPVASLPK CCCCCCCCCCCCCCH	22.68	19664994
309	Phosphorylation	DSLSPVASLPKQIFQ CCCCCCCCCCHHHCC	45.50	30266825
312	Sumoylation	SPVASLPKQIFQPSV CCCCCCCHHHCCCCC	62.41	28112733
312	Ubiquitination	SPVASLPKQIFQPSV CCCCCCCHHHCCCCC	62.41	-
325	Sumoylation	SVQQQPTKPVKVTCA CCCCCCCCCEEEEEC	55.27	-
325	Sumoylation	SVQQQPTKPVKVTCA CCCCCCCCCEEEEEC	55.27	28112733
325	Ubiquitination	SVQQQPTKPVKVTCA CCCCCCCCCEEEEEC	55.27	-
340	Ubiquitination	NCKKPLQKGQTAYQR CCCCCCCCCCCHHHC	61.75	-
343	Phosphorylation	KPLQKGQTAYQRKGS CCCCCCCCHHHCCCC	35.68	-
348	Sumoylation	GQTAYQRKGSAHLFC CCCHHHCCCCCEEEE	41.51	28112733
362	Phosphorylation	CSTTCLSSFSHKPAP EECHHHHHCCCCCCC	20.16	22817900
366	Sumoylation	CLSSFSHKPAPKKLC HHHHCCCCCCCCCEE	41.50	-
366	Sumoylation	CLSSFSHKPAPKKLC HHHHCCCCCCCCCEE	41.50	28112733
417	Sumoylation	EDKQNPTKGALNKSR HCCCCCCCCCCCHHH	43.36	-
417	Sumoylation	EDKQNPTKGALNKSR HCCCCCCCCCCCHHH	43.36	28112733
417	Ubiquitination	EDKQNPTKGALNKSR HCCCCCCCCCCCHHH	43.36	-
439	Phosphorylation	TEIRHEVSFKNMTHK HHEEEEECCCCCHHH	27.76	27251275
441	Sumoylation	IRHEVSFKNMTHKLC EEEEECCCCCHHHHH	38.00	-
441	Sumoylation	IRHEVSFKNMTHKLC EEEEECCCCCHHHHH	38.00	28112733
441	Ubiquitination	IRHEVSFKNMTHKLC EEEEECCCCCHHHHH	38.00	-
446	Ubiquitination	SFKNMTHKLCSDHCF CCCCCHHHHHHHHHC	41.86	-
476	Phosphorylation	QCGEYLPSKGAGNNV HHHCCCCCCCCCCCE	40.92	24719451
491	Sumoylation	LVIDGQQKRFCCQSC EEECCCCCEEECHHH	39.28	-
491	Sumoylation	LVIDGQQKRFCCQSC EEECCCCCEEECHHH	39.28	28112733
491	Ubiquitination	LVIDGQQKRFCCQSC EEECCCCCEEECHHH	39.28	-
502	Phosphorylation	CQSCVSEYKQVGSHP CHHHHHHHHHHCCCH	10.14	19658100
503	Sumoylation	QSCVSEYKQVGSHPS HHHHHHHHHHCCCHH	34.16	28112733
503	Ubiquitination	QSCVSEYKQVGSHPS HHHHHHHHHHCCCHH	34.16	-
510	Phosphorylation	KQVGSHPSFLKEVRD HHHCCCHHHHHHHHH	37.47	24719451
513	Sumoylation	GSHPSFLKEVRDHMQ CCCHHHHHHHHHHHH	52.75	28112733
513	Ubiquitination	GSHPSFLKEVRDHMQ CCCHHHHHHHHHHHH	52.75	-
522	Phosphorylation	VRDHMQDSFLMQPEK HHHHHHHCCCCCHHH	11.91	23663014
529	Sumoylation	SFLMQPEKYGKLTTC CCCCCHHHHCCCEEC	67.02	-
529	Sumoylation	SFLMQPEKYGKLTTC CCCCCHHHHCCCEEC	67.02	28112733
529	Ubiquitination	SFLMQPEKYGKLTTC CCCCCHHHHCCCEEC	67.02	-
532	Sumoylation	MQPEKYGKLTTCTGC CCHHHHCCCEECCCC	39.30	-
532	Sumoylation	MQPEKYGKLTTCTGC CCHHHHCCCEECCCC	39.30	28112733
532	Ubiquitination	MQPEKYGKLTTCTGC CCHHHHCCCEECCCC	39.30	-
557	Phosphorylation	QCIGPNGYMEPYCST CCCCCCCCCCCCCCH	12.63	19658100
561	Phosphorylation	PNGYMEPYCSTACMN CCCCCCCCCCHHHHH	5.92	22210691
563	Phosphorylation	GYMEPYCSTACMNSH CCCCCCCCHHHHHCC	17.13	22210691
564	Phosphorylation	YMEPYCSTACMNSHK CCCCCCCHHHHHCCC	21.95	22210691
569	Phosphorylation	CSTACMNSHKTKYAK CCHHHHHCCCCHHHH	10.24	22210691
576	Sumoylation	SHKTKYAKSQSLGII CCCCHHHHHCCHHHH	46.03	-
576	Sumoylation	SHKTKYAKSQSLGII CCCCHHHHHCCHHHH	46.03	28112733
579	Phosphorylation	TKYAKSQSLGIICHF CHHHHHCCHHHHHHH	35.34	24173317
591	Phosphorylation	CHFCKRNSLPQYQAT HHHHHHCCCCCEEEE	45.52	28555341
595	Phosphorylation	KRNSLPQYQATMPDG HHCCCCCEEEECCCC	9.74	19658100
603	Sumoylation	QATMPDGKLYNFCNS EEECCCCCEEECCCH	56.00	-
603	Sumoylation	QATMPDGKLYNFCNS EEECCCCCEEECCCH	56.00	28112733
603	Ubiquitination	QATMPDGKLYNFCNS EEECCCCCEEECCCH	56.00	-
605	Phosphorylation	TMPDGKLYNFCNSSC ECCCCCEEECCCHHH	15.07	19658100
610	Phosphorylation	KLYNFCNSSCVAKFQ CEEECCCHHHHHHHH	26.71	-
620	Phosphorylation	VAKFQALSMQSSPNG HHHHHHHHCCCCCCC	20.14	28464451
623	Phosphorylation	FQALSMQSSPNGQFV HHHHHCCCCCCCCEE	38.84	25159151
624	Phosphorylation	QALSMQSSPNGQFVA HHHHCCCCCCCCEEC	12.90	25159151
633	Phosphorylation	NGQFVAPSDIQLKCN CCCEECCHHEEEECC	37.29	26074081
638	Ubiquitination	APSDIQLKCNYCKNS CCHHEEEECCCCCCC	12.21	-
649	Sumoylation	CKNSFCSKPEILEWE CCCCCCCCHHHHHHH	48.10	-
649	Sumoylation	CKNSFCSKPEILEWE CCCCCCCCHHHHHHH	48.10	28112733
649	Ubiquitination	CKNSFCSKPEILEWE CCCCCCCCHHHHHHH	48.10	-
658	Sumoylation	EILEWENKVHQFCSK HHHHHHHHHHHHHHH	29.58	28112733
658	Ubiquitination	EILEWENKVHQFCSK HHHHHHHHHHHHHHH	29.58	-
665	Ubiquitination	KVHQFCSKTCSDDYK HHHHHHHHHCCCHHH	55.52	-
680	Phosphorylation	KLHCIVTYCEYCQEE HHHEEEHHHHHHHHH	3.41	19658100
683	Phosphorylation	CIVTYCEYCQEEKTL EEEHHHHHHHHHCCH	8.89	19658100
688	Sumoylation	CEYCQEEKTLHETVN HHHHHHHCCHHCEEC	56.48	28112733
697	Phosphorylation	LHETVNFSGVKRPFC HHCEECCCCCCCCCC	37.16	28555341
700	Sumoylation	TVNFSGVKRPFCSEG EECCCCCCCCCCCCC	58.86	28112733
700	Ubiquitination	TVNFSGVKRPFCSEG EECCCCCCCCCCCCC	58.86	-
709	Sumoylation	PFCSEGCKLLYKQDF CCCCCCCCEEHHHHH	53.00	28112733
709	Ubiquitination	PFCSEGCKLLYKQDF CCCCCCCCEEHHHHH	53.00	-
712	Phosphorylation	SEGCKLLYKQDFARR CCCCCEEHHHHHHHH	19.62	-
713	Ubiquitination	EGCKLLYKQDFARRL CCCCEEHHHHHHHHH	43.28	-
729	Phosphorylation	LRCVTCNYCSQLCKK CEEEECHHHHHHHHC	8.81	19658100
735	Ubiquitination	NYCSQLCKKGATKEL HHHHHHHHCCCCCCC	63.93	-
736	Ubiquitination	YCSQLCKKGATKELD HHHHHHHCCCCCCCC	53.43	-
740	Ubiquitination	LCKKGATKELDGVVR HHHCCCCCCCCHHHH	56.60	-
757	Sumoylation	CSEDCCKKFQDWYYK CCHHHHHHHHHHHHH	34.05	-
757	Sumoylation	CSEDCCKKFQDWYYK CCHHHHHHHHHHHHH	34.05	-
757	Ubiquitination	CSEDCCKKFQDWYYK CCHHHHHHHHHHHHH	34.05	-
764	Sumoylation	KFQDWYYKAARCDCC HHHHHHHHHHCCCHH	21.63	28112733
772	Ubiquitination	AARCDCCKSQGTLKE HHCCCHHCCCCCHHH	52.74	-
788	Sumoylation	VQWRGEMKHFCDQHC EECCHHHHHHHHHHH	29.27	28112733
800	Phosphorylation	QHCLLRFYCQQNEPN HHHHHHHHHCCCCCC	5.28	-
812	Sumoylation	EPNMTTQKGPENLHY CCCCCCCCCCCCCCC	74.47	28112733
812	Ubiquitination	EPNMTTQKGPENLHY CCCCCCCCCCCCCCC	74.47	-
819	Phosphorylation	KGPENLHYDQGCQTS CCCCCCCCCCCCCCC	17.09	27642862
829	Sumoylation	GCQTSRTKMTGSAPP CCCCCCCCCCCCCCC	33.10	28112733
831	Phosphorylation	QTSRTKMTGSAPPPS CCCCCCCCCCCCCCC	29.55	29255136
833	Phosphorylation	SRTKMTGSAPPPSPT CCCCCCCCCCCCCCC	28.56	29255136
838	Phosphorylation	TGSAPPPSPTPNKEM CCCCCCCCCCCCHHH	47.37	19664994
840	Phosphorylation	SAPPPSPTPNKEMKN CCCCCCCCCCHHHCC	43.78	30266825
856	Phosphorylation	AVLCKPLTMTKATYC EEEEECCCCCCCCCC	31.18	29083192
858	Phosphorylation	LCKPLTMTKATYCKP EEECCCCCCCCCCCC	16.58	29083192
862	Phosphorylation	LTMTKATYCKPHMQT CCCCCCCCCCCCCCC	11.88	-
938	Sumoylation	PAAIEELKSKVSSDA HHHHHHHHHHHCCHH	52.06	-
938	Sumoylation	PAAIEELKSKVSSDA HHHHHHHHHHHCCHH	52.06	-
938	Ubiquitination	PAAIEELKSKVSSDA HHHHHHHHHHHCCHH	52.06	-
939	Phosphorylation	AAIEELKSKVSSDAL HHHHHHHHHHCCHHH	51.41	27251275
942	Phosphorylation	EELKSKVSSDALDTE HHHHHHHCCHHHCHH	26.66	27251275
943	Phosphorylation	ELKSKVSSDALDTEL HHHHHHCCHHHCHHH	29.86	27251275
952	Phosphorylation	ALDTELLTMTDMMSE HHCHHHHHHHHCCCC	30.56	26074081
954	Phosphorylation	DTELLTMTDMMSEDE CHHHHHHHHCCCCCC	18.60	26074081
958	Phosphorylation	LTMTDMMSEDEGKTE HHHHHCCCCCCCCCC	34.95	27362937
963	Sumoylation	MMSEDEGKTETTNIN CCCCCCCCCCCCCCC	40.93	-
963	Sumoylation	MMSEDEGKTETTNIN CCCCCCCCCCCCCCC	40.93	-
985	Sumoylation	IIGSDLLKNSDPETQ CCCHHHHCCCCCCCC	62.80	-
1033	Phosphorylation	PPVFGEEYEEQPRPR CCCCCCCCCCCCCCC	22.06	27642862
1049	Ubiquitination	KKKGAKRKAVSGYQS CCCCCCCCCCCCCCC	53.05	-
1052	Phosphorylation	GAKRKAVSGYQSHDD CCCCCCCCCCCCCCC	36.32	30266825
1054	Phosphorylation	KRKAVSGYQSHDDSS CCCCCCCCCCCCCCC	10.19	22617229
1056	Phosphorylation	KAVSGYQSHDDSSDN CCCCCCCCCCCCCCC	22.02	23401153
1060	Phosphorylation	GYQSHDDSSDNSECS CCCCCCCCCCCCCCC	45.72	30266825
1061	Phosphorylation	YQSHDDSSDNSECSF CCCCCCCCCCCCCCC	48.05	30266825
1064	Phosphorylation	HDDSSDNSECSFPFK CCCCCCCCCCCCCCE	44.99	22617229
1067	Phosphorylation	SSDNSECSFPFKYTY CCCCCCCCCCCEEEE	31.72	23663014
1080	Sumoylation	TYGVNAWKHWVKTRQ EECCCCHHHHHHHHC	25.77	-
1080	Sumoylation	TYGVNAWKHWVKTRQ EECCCCHHHHHHHHC	25.77	-
1080	Ubiquitination	TYGVNAWKHWVKTRQ EECCCCHHHHHHHHC	25.77	-
1099	Sumoylation	LLVLDELKSSKSVKL EEHHHHHHCCCCCCC	51.11	-
1099	Sumoylation	LLVLDELKSSKSVKL EEHHHHHHCCCCCCC	51.11	-
1099	Ubiquitination	LLVLDELKSSKSVKL EEHHHHHHCCCCCCC	51.11	-
1100	Phosphorylation	LVLDELKSSKSVKLK EHHHHHHCCCCCCCH	56.47	27135362
1101	Phosphorylation	VLDELKSSKSVKLKE HHHHHHCCCCCCCHH	27.62	27135362
1102	Acetylation	LDELKSSKSVKLKED HHHHHCCCCCCCHHH	67.37	30593621
1102	Ubiquitination	LDELKSSKSVKLKED HHHHHCCCCCCCHHH	67.37	-
1103	Phosphorylation	DELKSSKSVKLKEDL HHHHCCCCCCCHHHH	26.82	27135362
1105	Ubiquitination	LKSSKSVKLKEDLLS HHCCCCCCCHHHHHH	62.02	-
1114	Phosphorylation	KEDLLSHTTAELNYG HHHHHHHHHHHHHHH	25.07	-
1159	Ubiquitination	YLCGSNRKDNIFIDP HHCCCCCCCCEEECC	60.42	-
1177	Ubiquitination	TFEQELNKILRSWQP HHHHHHHHHHHHCCC	56.60	-
1181	Phosphorylation	ELNKILRSWQPSILP HHHHHHHHCCCCCCC	26.98	30631047
1185	Phosphorylation	ILRSWQPSILPDGSI HHHHCCCCCCCCCCH	22.96	30631047
1191	Phosphorylation	PSILPDGSIFSRVEE CCCCCCCCHHHHHCH	28.04	30631047
1218	Phosphorylation	SPVALLNTLFYFNTK CHHHHHHHHHHCCCC	20.43	-
1221	Phosphorylation	ALLNTLFYFNTKYFG HHHHHHHHCCCCCCC	10.07	-
1224	Phosphorylation	NTLFYFNTKYFGLKT HHHHHCCCCCCCCCH	19.75	-
1230	Ubiquitination	NTKYFGLKTVEQHLR CCCCCCCCHHHHHHH	51.40	-
1239	Phosphorylation	VEQHLRLSFGTVFRH HHHHHHHHHHHHHHH	18.39	21406692
1242	Phosphorylation	HLRLSFGTVFRHWKK HHHHHHHHHHHHHCC	17.92	21406692
1249	Ubiquitination	TVFRHWKKNPLTMEN HHHHHHCCCCCCCCC	59.62	-
1253	O-linked_Glycosylation	HWKKNPLTMENKACL HHCCCCCCCCCHHHH	24.56	30379171
1253	Phosphorylation	HWKKNPLTMENKACL HHCCCCCCCCCHHHH	24.56	-
1257	Sumoylation	NPLTMENKACLRYQV CCCCCCCHHHHHHHH	27.46	-
1257	Acetylation	NPLTMENKACLRYQV CCCCCCCHHHHHHHH	27.46	26822725
1257	Sumoylation	NPLTMENKACLRYQV CCCCCCCHHHHHHHH	27.46	-
1257	Ubiquitination	NPLTMENKACLRYQV CCCCCCCHHHHHHHH	27.46	-
1275	Acetylation	CGTDNEDKITTGKRK CCCCCCCCCCCCCCC	35.46	25953088
1275	Ubiquitination	CGTDNEDKITTGKRK CCCCCCCCCCCCCCC	35.46	-
1280	Acetylation	EDKITTGKRKHEDDE CCCCCCCCCCCCCCC	57.06	23749302
1280	Ubiquitination	EDKITTGKRKHEDDE CCCCCCCCCCCCCCC	57.06	-
1282	Sumoylation	KITTGKRKHEDDEPV CCCCCCCCCCCCCCH	55.63	-
1282	Sumoylation	KITTGKRKHEDDEPV CCCCCCCCCCCCCCH	55.63	-
1282	Ubiquitination	KITTGKRKHEDDEPV CCCCCCCCCCCCCCH	55.63	-
1305	Ubiquitination	NPSRCPVKMFECYLS CCCCCCCEEEEEECC	24.02	-
1313	Acetylation	MFECYLSKSPQNLNQ EEEEECCCCCCCHHH	64.66	26051181
1313	Ubiquitination	MFECYLSKSPQNLNQ EEEEECCCCCCCHHH	64.66	-
1362	Ubiquitination	LVRVLLVKDIYDKDN HHHHHHHHHHHCCCC	38.08	-
1367	Ubiquitination	LVKDIYDKDNYELDE HHHHHHCCCCCCCCC	30.79	-
1376	Phosphorylation	NYELDEDTD------ CCCCCCCCC------	41.37	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
303	S	Phosphorylation	Kinase	PLK1	P53350	PSP
305	S	Phosphorylation	Kinase	PLK1	P53350	PSP
309	S	Phosphorylation	Kinase	PLK1	P53350	PSP
502	Y	Phosphorylation	Kinase	FGFR1	P11362	PSP
557	Y	Phosphorylation	Kinase	FGFR1	P11362	PSP
595	Y	Phosphorylation	Kinase	FGFR1	P11362	PSP
605	Y	Phosphorylation	Kinase	FGFR1	P11362	PSP
680	Y	Phosphorylation	Kinase	FGFR1	P11362	PSP
683	Y	Phosphorylation	Kinase	FGFR1	P11362	PSP
729	Y	Phosphorylation	Kinase	FGFR1	P11362	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZMYM2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZMYM2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FUS_HUMAN	FUS	physical	15975576
SFPQ_HUMAN	SFPQ	physical	15975576
HNRH3_HUMAN	HNRNPH3	physical	15975576
ROA2_HUMAN	HNRNPA2B1	physical	15975576
UBF1_HUMAN	UBTF	physical	15975576
ZMYM4_HUMAN	ZMYM4	physical	18806873
KDM1A_HUMAN	KDM1A	physical	18806873
HSP74_HUMAN	HSPA4	physical	18806873
RCOR1_HUMAN	RCOR1	physical	18806873
HDAC1_HUMAN	HDAC1	physical	18806873
HDAC2_HUMAN	HDAC2	physical	18806873
TBA1B_HUMAN	TUBA1B	physical	18806873
TBB1_HUMAN	TUBB1	physical	18806873
ZBTB3_HUMAN	ZBTB3	physical	20211142
PML_HUMAN	PML	physical	17027752
UBE2A_HUMAN	UBE2A	physical	12776193
UBE2B_HUMAN	UBE2B	physical	12776193
RAD18_HUMAN	RAD18	physical	12776193
PML_HUMAN	PML	physical	25133527
SUMO2_HUMAN	SUMO2	physical	25133527

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZMYM2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305 AND THR-1376, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305; SER-624; SER-833;SER-838 AND THR-840, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-838 AND THR-1376, ANDMASS SPECTROMETRY.	18669648 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305, AND MASSSPECTROMETRY.	16964243 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-362 AND SER-838, ANDMASS SPECTROMETRY.	15302935 [Abstract]