MYH4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYH4_HUMAN
• UniProt AC: Q9Y623
• Protein Name: Myosin-4
• Gene Name: MYH4
• Organism: Homo sapiens (Human).
• Sequence Length: 1939
• Subcellular Localization: Cytoplasm, myofibril. Thick filaments of the myofibrils.
• Protein Description: Muscle contraction..
• Protein Sequence: MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVISEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	Phosphorylation	SREGGKVTAKTEAGA CCCCCEEEEEECCCC	26.39	-
64	Phosphorylation	GGKVTAKTEAGATVT CCEEEEEECCCCEEE	28.71	26437602
69	Phosphorylation	AKTEAGATVTVKEDQ EEECCCCEEEECCCH	18.78	26074081
79	Phosphorylation	VKEDQVFSMNPPKYD ECCCHHEECCCCCCC	20.85	-
95	Phosphorylation	IEDMAMMTHLHEPAV HHHHHHHHCCCCHHH	14.27	26437602
104	Phosphorylation	LHEPAVLYNLKERYA CCCHHHHCCHHHHHH	16.32	26437602
130	"N6,N6,N6-trimethyllysine"	CVTVNPYKWLPVYNP EEEECCCCCCCCCCH	43.44	-
130	Methylation	CVTVNPYKWLPVYNP EEEECCCCCCCCCCH	43.44	-
157	Phosphorylation	EAPPHIFSISDNAYQ CCCCCEEECCCCEEE	22.15	25850435
159	Phosphorylation	PPHIFSISDNAYQFM CCCEEECCCCEEEEE	24.50	25850435
163	Phosphorylation	FSISDNAYQFMLTDR EECCCCEEEEEECCC	14.45	25850435
168	Phosphorylation	NAYQFMLTDRENQSI CEEEEEECCCCCCEE	22.63	-
174	Phosphorylation	LTDRENQSILITGES ECCCCCCEEEEECCC	30.83	26437602
181	Phosphorylation	SILITGESGAGKTVN EEEEECCCCCCCCCC	34.98	26437602
195	Phosphorylation	NTKRVIQYFATIAVT CHHHHHHHEEEEECC	5.53	25850435
198	Phosphorylation	RVIQYFATIAVTGEK HHHHHEEEEECCCCC	10.28	25850435
202	Phosphorylation	YFATIAVTGEKKKEE HEEEEECCCCCCCCC	30.51	21406692
237	Ubiquitination	LEAFGNAKTVRNDNS HHHHCCCEEECCCCC	52.10	22817900
244	Phosphorylation	KTVRNDNSSRFGKFI EEECCCCCCCCCEEE	26.25	29514088
245	Phosphorylation	TVRNDNSSRFGKFIR EECCCCCCCCCEEEE	37.57	29514088
249	Ubiquitination	DNSSRFGKFIRIHFG CCCCCCCEEEEEEEC	34.60	-
258	Phosphorylation	IRIHFGATGKLASAD EEEEECCCCCCCCCC	34.92	26437602
263	Phosphorylation	GATGKLASADIETYL CCCCCCCCCCHHHHH	36.59	22673903
268	Phosphorylation	LASADIETYLLEKSR CCCCCHHHHHHHCCE	21.58	22673903
269	Phosphorylation	ASADIETYLLEKSRV CCCCHHHHHHHCCEE	9.12	22817900
273	Ubiquitination	IETYLLEKSRVTFQL HHHHHHHCCEEEEEE	43.46	29901268
274	Phosphorylation	ETYLLEKSRVTFQLK HHHHHHCCEEEEEEE	23.70	26437602
277	Phosphorylation	LLEKSRVTFQLKAER HHHCCEEEEEEEEEC	12.45	26437602
356	Phosphorylation	KVAIYKLTGAVMHYG CHHHHHHHHHHHHHC	20.95	21712546
362	Phosphorylation	LTGAVMHYGNMKFKQ HHHHHHHHCCCCHHH	7.66	21712546
381	Phosphorylation	EQAEPDGTEVADKAA HHCCCCCCCHHHHHH	34.37	26437602
389	Phosphorylation	EVADKAAYLTSLNSA CHHHHHHHHHCCCHH	18.51	22817900
391	Phosphorylation	ADKAAYLTSLNSADL HHHHHHHHCCCHHHH	20.63	28348404
392	Phosphorylation	DKAAYLTSLNSADLL HHHHHHHCCCHHHHH	23.98	28348404
419	Phosphorylation	EFVTKGQTVQQVYNA EEECCCCHHHHHHHH	29.02	26437602
424	Phosphorylation	GQTVQQVYNAVGALA CCHHHHHHHHHHHHH	7.96	26437602
452	Phosphorylation	RINQQLDTKQPRQYF HHHHHCCCCCCCHHE	39.92	26437602
505	Acetylation	VLEQEEYKKEGIEWE EECHHHHHHCCCCEE	47.86	30585061
556	Phosphorylation	TSFKNKLYEQHLGKS CHHHHHHHHHHCCCC	18.36	20049867
607	Phosphorylation	NKDPLNETVVGLYQK CCCCCCHHHHHHHHH	21.30	-
612	Phosphorylation	NETVVGLYQKSAMKT CHHHHHHHHHHHHHH	14.15	26437602
625	Phosphorylation	KTLAFLFSGAQTAEA HHHHHHHHCCCCCCC	35.05	-
646	Phosphorylation	KGGKKKGSSFQTVSA CCCCCCCCCHHHHHH	36.54	26437602
647	Phosphorylation	GGKKKGSSFQTVSAL CCCCCCCCHHHHHHH	30.00	26437602
650	Phosphorylation	KKGSSFQTVSALFRE CCCCCHHHHHHHHHH	17.89	26437602
664	Phosphorylation	ENLNKLMTNLRSTHP HHHHHHHHHHHHHCC	41.35	19764811
668	Phosphorylation	KLMTNLRSTHPHFVR HHHHHHHHHCCCEEE	33.94	26437602
669	Phosphorylation	LMTNLRSTHPHFVRC HHHHHHHHCCCEEEE	32.75	26437602
682	Phosphorylation	RCIIPNETKTPGAME EEECCCCCCCCCCCH	47.02	26437602
684	Phosphorylation	IIPNETKTPGAMEHE ECCCCCCCCCCCHHH	34.08	26437602
719	Phosphorylation	GFPSRILYADFKQRY CCCCEEEECCHHHHH	11.18	22817900
732	Phosphorylation	RYKVLNASAIPEGQF HHHHHCHHHCCCCCC	26.17	19764811
742	Phosphorylation	PEGQFIDSKKASEKL CCCCCCCCHHHHHHH	31.10	19764811
744	Acetylation	GQFIDSKKASEKLLG CCCCCCHHHHHHHHC	62.18	30585097
746	Phosphorylation	FIDSKKASEKLLGSI CCCCHHHHHHHHCCE	44.11	19764811
757	Methylation	LGSIEIDHTQYKFGH HCCEEEECCEEECCC	22.11	-
758	Phosphorylation	GSIEIDHTQYKFGHT CCEEEECCEEECCCC	29.82	26437602
776	Phosphorylation	FKAGLLGTLEEMRDE HHHCHHHHHHHHCHH	30.85	-
790	Phosphorylation	EKLAQLITRTQAICR HHHHHHHHHHHHHHH	35.93	26437602
820	Phosphorylation	ESIFCIQYNIRAFMN HHHEEEEEHHHHHHC	7.82	-
857	"N6,N6-dimethyllysine"	EKEMANMKEEFEKTK HHHHHHHHHHHHHHH	54.63	-
857	Methylation	EKEMANMKEEFEKTK HHHHHHHHHHHHHHH	54.63	-
862	"N6,N6-dimethyllysine"	NMKEEFEKTKEELAK HHHHHHHHHHHHHHH	70.93	-
862	Methylation	NMKEEFEKTKEELAK HHHHHHHHHHHHHHH	70.93	-
915	Phosphorylation	RCDQLIKTKIQLEAK HHHHHHHHHHHHHHH	26.79	26437602
922	Acetylation	TKIQLEAKIKEVTER HHHHHHHHHHHHHHH	44.96	19820379
927	Phosphorylation	EAKIKEVTERAEDEE HHHHHHHHHHCCCHH	22.35	28787133
941	Phosphorylation	EEINAELTAKKRKLE HHHHHHHHHHHHHHH	28.12	26437602
952	Phosphorylation	RKLEDECSELKKDID HHHHHHHHHHHHCHH	43.87	26437602
955	Acetylation	EDECSELKKDIDDLE HHHHHHHHHCHHHHH	44.33	160903
956	Acetylation	DECSELKKDIDDLEL HHHHHHHHCHHHHHH	72.96	30585079
964	Phosphorylation	DIDDLELTLAKVEKE CHHHHHHHHHHHHHH	18.46	22673903
983	Phosphorylation	ENKVKNLTEEMAGLD HHHHHHHHHHHHCHH	39.01	20068231
992	Phosphorylation	EMAGLDETIAKLTKE HHHCHHHHHHHHHHH	26.38	20068231
997	Phosphorylation	DETIAKLTKEKKALQ HHHHHHHHHHHHHHH	36.13	26437602
1023	Phosphorylation	MEEDKVNTLTKAKTK HHHHHHHHHHHHHHH	38.50	26437602
1029	Phosphorylation	NTLTKAKTKLEQQVD HHHHHHHHHHHHHHH	45.80	28258704
1030	Methylation	TLTKAKTKLEQQVDD HHHHHHHHHHHHHHH	49.69	-
1041	Phosphorylation	QVDDLEGSLEQEKKL HHHHCCCCHHHHHHH	21.25	28258704
1046	Acetylation	EGSLEQEKKLCMDLE CCCHHHHHHHHHHHH	51.22	30585055
1087	Methylation	LNEKLKKKEFEMSNL HHHHHHHHHHHHHHC	67.08	-
1092	Phosphorylation	KKKEFEMSNLQGKIE HHHHHHHHHCCCCCC	27.47	-
1097	Methylation	EMSNLQGKIEDEQAL HHHHCCCCCCHHHHH	29.93	-
1111	Acetylation	LAIQLQKKIKELQAR HHHHHHHHHHHHHHH	46.15	7693271
1113	Acetylation	IQLQKKIKELQARIE HHHHHHHHHHHHHHH	62.34	7693283
1130	Methylation	EEEIEAERASRAKAE HHHHHHHHHHHHHHH	44.93	16188145
1132	Phosphorylation	EIEAERASRAKAEKQ HHHHHHHHHHHHHHH	38.70	19764811
1141	Phosphorylation	AKAEKQRSDLSRELE HHHHHHHHHHHHHHH	40.17	19764811
1144	Phosphorylation	EKQRSDLSRELEEIS HHHHHHHHHHHHHHH	28.79	19764811
1151	Phosphorylation	SRELEEISERLEEAG HHHHHHHHHHHHHCC	21.68	22673903
1161	Phosphorylation	LEEAGGATSAQIEMN HHHCCCCCHHHHHHH	28.06	22673903
1162	Phosphorylation	EEAGGATSAQIEMNK HHCCCCCHHHHHHHH	20.03	19764811
1185	Phosphorylation	MRRDLEESTLQHEAT HHHHHHHHHHHHHHH	25.66	-
1186	Phosphorylation	RRDLEESTLQHEATA HHHHHHHHHHHHHHH	33.44	-
1192	Phosphorylation	STLQHEATAAALRKK HHHHHHHHHHHHHHH	17.53	-
1203	Phosphorylation	LRKKHADSVAELGEQ HHHHHHHHHHHHHHH	24.82	-
1223	Ubiquitination	RVKQKLEKEKSELKM HHHHHHHHHHHHHHH	79.48	-
1237	Phosphorylation	MEINDLASNMETVSK HHHHHHHHCHHHHHH	43.96	24719451
1241	Phosphorylation	DLASNMETVSKAKAN HHHHCHHHHHHHHHH	21.22	-
1243	Phosphorylation	ASNMETVSKAKANFE HHCHHHHHHHHHHHH	34.02	-
1251	Ubiquitination	KAKANFEKMCRTLED HHHHHHHHHHHHHHH	38.88	-
1255	Phosphorylation	NFEKMCRTLEDQLSE HHHHHHHHHHHHHHH	29.58	26437602
1261	Phosphorylation	RTLEDQLSEIKTKEE HHHHHHHHHCCCHHH	31.48	20068231
1264	Ubiquitination	EDQLSEIKTKEEEQQ HHHHHHCCCHHHHHH	49.87	-
1265	Phosphorylation	DQLSEIKTKEEEQQR HHHHHCCCHHHHHHH	49.72	20068231
1278	Phosphorylation	QRLINELSAQKARLH HHHHHHHHHHHHHHH	23.60	-
1286	Phosphorylation	AQKARLHTESGEFSR HHHHHHHCCCCCHHH	36.12	24719451
1288	Phosphorylation	KARLHTESGEFSRQL HHHHHCCCCCHHHHC	44.79	24719451
1292	Phosphorylation	HTESGEFSRQLDEKD HCCCCCHHHHCCHHH	18.15	-
1303	Phosphorylation	DEKDAMVSQLSRGKQ CHHHHHHHHHHHHHH	16.60	24719451
1306	Phosphorylation	DAMVSQLSRGKQAFT HHHHHHHHHHHHHHH	31.20	-
1313	Phosphorylation	SRGKQAFTQQIEELK HHHHHHHHHHHHHHH	23.68	19764811
1351	Phosphorylation	CDLLREQYEEEQEAK HHHHHHHHHHHHHHH	22.13	-
1366	Phosphorylation	AELQRGMSKANSEVA HHHHHHHHHHHHHHH	31.29	-
1370	Phosphorylation	RGMSKANSEVAQWRT HHHHHHHHHHHHHHH	38.00	19764811
1377	Phosphorylation	SEVAQWRTKYETDAI HHHHHHHHHHHHHHH	34.71	26437602
1379	Phosphorylation	VAQWRTKYETDAIQR HHHHHHHHHHHHHHH	24.37	19764811
1381	Phosphorylation	QWRTKYETDAIQRTE HHHHHHHHHHHHHHH	27.86	19764811
1387	Phosphorylation	ETDAIQRTEELEEAK HHHHHHHHHHHHHHH	19.89	20068231
1394	Acetylation	TEELEEAKKKLAQRL HHHHHHHHHHHHHHH	54.44	19863339
1395	Acetylation	EELEEAKKKLAQRLQ HHHHHHHHHHHHHHH	61.13	30585067
1396	Acetylation	ELEEAKKKLAQRLQD HHHHHHHHHHHHHHH	48.63	30585085
1413	Phosphorylation	EHVEAVNSKCASLEK HHHHHHHHHHHCHHH	23.63	24719451
1417	Phosphorylation	AVNSKCASLEKTKQR HHHHHHHCHHHHHHH	46.67	24719451
1421	Phosphorylation	KCASLEKTKQRLQNE HHHCHHHHHHHHHHH	24.04	24719451
1464	Phosphorylation	LAEWKQKYEETQAEL HHHHHHHHHHHHHHH	19.26	18669648
1467	Phosphorylation	WKQKYEETQAELEAS HHHHHHHHHHHHHHH	22.57	26074081
1474	Phosphorylation	TQAELEASQKESRSL HHHHHHHHHHHHHHH	32.20	-
1478	Phosphorylation	LEASQKESRSLSTEL HHHHHHHHHHHHHHH	33.92	18669648
1480	Phosphorylation	ASQKESRSLSTELFK HHHHHHHHHHHHHHH	35.63	18669648
1482	Phosphorylation	QKESRSLSTELFKVK HHHHHHHHHHHHHHH	22.53	18669648
1483	Phosphorylation	KESRSLSTELFKVKN HHHHHHHHHHHHHHH	41.84	18669648
1492	Phosphorylation	LFKVKNAYEESLDHL HHHHHHHHHHHHHHH	29.62	-
1495	Phosphorylation	VKNAYEESLDHLETL HHHHHHHHHHHHHHH	27.45	-
1501	Phosphorylation	ESLDHLETLKRENKN HHHHHHHHHHHHCHH	43.89	-
1514	Phosphorylation	KNLQQEISDLTEQIA HHHHHHHHHHHHHHH	26.30	22777824
1517	Phosphorylation	QQEISDLTEQIAEGG HHHHHHHHHHHHHCC	30.73	26437602
1542	Phosphorylation	KQLDHEKSELQTSLE HHHHHHHHHHHHHHH	40.32	-
1547	Phosphorylation	EKSELQTSLEEAEAS HHHHHHHHHHHHHHH	22.33	-
1554	Phosphorylation	SLEEAEASLEHEEGK HHHHHHHHHHHCCCC	26.29	-
1574	Phosphorylation	LELNQVKSEIDRKIA HHHHHHHHHHHHHHH	40.71	24719451
1600	Phosphorylation	NHLRVVESMQSTLDA HHHHHHHHHHHHHHH	15.54	28348404
1603	Phosphorylation	RVVESMQSTLDAEIR HHHHHHHHHHHHHHH	23.46	24719451
1604	Phosphorylation	VVESMQSTLDAEIRS HHHHHHHHHHHHHHC	16.27	-
1611	Phosphorylation	TLDAEIRSRNDALRI HHHHHHHCHHHHHHH	40.89	26437602
1650	Phosphorylation	ALRNLRNTQGILKDT HHHHHHHHCCHHHHH	23.03	26437602
1657	Phosphorylation	TQGILKDTQLHLDDA HCCHHHHHHHCHHHH	31.29	26437602
1714	Phosphorylation	EQELLDASERVQLLH HHHHHCHHHHHHHHH	26.13	20068231
1722	Phosphorylation	ERVQLLHTQNTSLIN HHHHHHHHCCCCCCC	24.39	19764811
1725	Phosphorylation	QLLHTQNTSLINTKK HHHHHCCCCCCCCHH	18.32	19764811
1726	Phosphorylation	LLHTQNTSLINTKKK HHHHCCCCCCCCHHH	34.50	22777824
1730	Phosphorylation	QNTSLINTKKKLETD CCCCCCCCHHHHHHC	36.93	19764811
1731	Acetylation	NTSLINTKKKLETDI CCCCCCCHHHHHHCH	43.34	19863363
1736	Phosphorylation	NTKKKLETDISQIQG CCHHHHHHCHHHHHH	49.41	-
1739	Phosphorylation	KKLETDISQIQGEME HHHHHCHHHHHHHHH	24.84	24719451
1764	Phosphorylation	EKAKKAITDAAMMAE HHHHHHHHHHHHHHH	25.17	30576142
1774	Acetylation	AMMAEELKKEQDTSA HHHHHHHHHHHCCHH	58.50	30585091
1775	Ubiquitination	MMAEELKKEQDTSAH HHHHHHHHHHCCHHH	73.55	30230243
1779	Phosphorylation	ELKKEQDTSAHLERM HHHHHHCCHHHHHHH	27.75	26437602
1780	Phosphorylation	LKKEQDTSAHLERMK HHHHHCCHHHHHHHH	23.21	26437602
1788	Acetylation	AHLERMKKNMEQTVK HHHHHHHHHHHHHHH	52.78	7704599
1793	Phosphorylation	MKKNMEQTVKDLQLR HHHHHHHHHHHHHHH	19.06	26437602
1795	Acetylation	KNMEQTVKDLQLRLD HHHHHHHHHHHHHHH	56.99	7704611
1810	Ubiquitination	EAEQLALKGGKKQIQ HHHHHHHHCCHHHHH	61.07	22817900
1813	Ubiquitination	QLALKGGKKQIQKLE HHHHHCCHHHHHHHH	50.61	22817900
1814	Ubiquitination	LALKGGKKQIQKLEA HHHHCCHHHHHHHHH	56.77	22817900
1818	Ubiquitination	GGKKQIQKLEARVRE CCHHHHHHHHHHHHH	50.34	22817900
1855	Phosphorylation	ERRVKELTYQTEEDR HHHHHHHHCCCHHHH	18.06	19764811
1856	Phosphorylation	RRVKELTYQTEEDRK HHHHHHHCCCHHHHH	26.51	26437602
1858	Phosphorylation	VKELTYQTEEDRKNI HHHHHCCCHHHHHHH	30.81	26437602
1863	Acetylation	YQTEEDRKNILRLQD CCCHHHHHHHHHHHH	61.74	30585073
1882	Phosphorylation	LQTKVKAYKRQAEEA HHHHHHHHHHHHHHH	10.86	24719451
1919	Phosphorylation	ERADIAESQVNKLRV HHHHHHHHHHHHHHH	30.33	19764811
1928	Phosphorylation	VNKLRVKSREVHTKV HHHHHHCCCCHHHHH	30.71	26437602

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYH4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYH4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYH4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ACTN2_HUMAN	ACTN2	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1464; SER-1478;SER-1480; SER-1482 AND THR-1483, AND MASS SPECTROMETRY.
PubMed: 18669648

Ubiquitylation

"Tryptic digestion of ubiquitin standards reveals an improved strategyfor identifying ubiquitinated proteins by mass spectrometry.";
Denis N.J., Vasilescu J., Lambert J.-P., Smith J.C., Figeys D.;
Proteomics 7:868-874(2007).
Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-1813, AND MASSSPECTROMETRY.
PubMed: 17370265