KRT85_HUMAN - dbPTM
KRT85_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KRT85_HUMAN
UniProt AC P78386
Protein Name Keratin, type II cuticular Hb5
Gene Name KRT85
Organism Homo sapiens (Human).
Sequence Length 507
Subcellular Localization
Protein Description
Protein Sequence MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSSRSVRFA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSCRSYRIS
------CCCCCEEEC		20.45-
79PhosphorylationRAGSCGRSFGYRSGG
ECCCCCCCCCCCCCC		14.3324719451
149UbiquitinationRFLEQQNKLLETKWQ
HHHHHHHHHHHHHHH		50.54-
229UbiquitinationENEFVVLKKDVDCAY
CCCEEEEECCCCCEE		35.00-
229SumoylationENEFVVLKKDVDCAY
CCCEEEEECCCCCEE		35.0025114211
230UbiquitinationNEFVVLKKDVDCAYL
CCEEEEECCCCCEEE		59.84-
254PhosphorylationEALVEESSFLRRLYE
HHHHHHCHHHHHHHH		31.4224719451
260PhosphorylationSSFLRRLYEEEIRVL
CHHHHHHHHHHHHHH		21.3420071362
306PhosphorylationYDDVASRSRAEAESW
HHHHHHHHHHHHHHH		33.0928348404
312PhosphorylationRSRAEAESWYRSKCE
HHHHHHHHHHHHHHH		36.1328348404
314PhosphorylationRAEAESWYRSKCEEM
HHHHHHHHHHHHHHH		17.81-
317UbiquitinationAESWYRSKCEEMKAT
HHHHHHHHHHHHHHH		36.35-
322UbiquitinationRSKCEEMKATVIRHG
HHHHHHHHHHHHHCC		44.15-
324PhosphorylationKCEEMKATVIRHGET
HHHHHHHHHHHCCHH		15.7924719451
331PhosphorylationTVIRHGETLRRTKEE
HHHHCCHHHHHHHHH		30.1124719451
335PhosphorylationHGETLRRTKEEINEL
CCHHHHHHHHHHHHH		36.0524719451
336UbiquitinationGETLRRTKEEINELN
CHHHHHHHHHHHHHH		52.09-
384UbiquitinationALSDARCKLAELEGA
HHHHHHHHHHHHHHH		45.22-
394UbiquitinationELEGALQKAKQDMAC
HHHHHHHHHHHHHHH		59.40-
396UbiquitinationEGALQKAKQDMACLL
HHHHHHHHHHHHHHH		54.59-
410SulfoxidationLKEYQEVMNSKLGLD
HHHHHHHHHHCCCCC		4.6328183972
412PhosphorylationEYQEVMNSKLGLDIE
HHHHHHHHCCCCCEE		15.9127251275
493PhosphorylationCAPCQPRSSSFSCGS
CCCCCCCCCCCCCCC		36.70-
494PhosphorylationAPCQPRSSSFSCGSS
CCCCCCCCCCCCCCC		36.36-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KRT85_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KRT85_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KRT85_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of KRT85_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KRT85_HUMAN

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Related Literatures of Post-Translational Modification

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