KT33B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KT33B_HUMAN
• UniProt AC: Q14525
• Protein Name: Keratin, type I cuticular Ha3-II
• Gene Name: KRT33B
• Organism: Homo sapiens (Human).
• Sequence Length: 404
• Protein Sequence: MPYNFCLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACEKPIGSCVTNPCGPRSRCGPCNTFGY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	Phosphorylation	LNDRLASYLEKVRQL HHHHHHHHHHHHHHH	17.17	-
92	Phosphorylation	ENLIRERSQQQEPLL HHHHHHHHHCCCCCC	27.82	-
109	Phosphorylation	SYQSYFKTIEELQQK HHHHHHHHHHHHHHH	24.58	-
157	Phosphorylation	SLRQLVESDINSLRR HHHHHHHHHHHHHHH	35.99	20068231
161	Phosphorylation	LVESDINSLRRILDE HHHHHHHHHHHHHHH	24.48	20068231
189	Phosphorylation	SLKEELLSLKQNHEQ HHHHHHHHHHHHHHH	46.26	24719451
261	Phosphorylation	LNKQVVSSSEQLQSY HHHHHCCCHHHHHHH	26.70	24719451
268	Phosphorylation	SSEQLQSYQAEIIEL CHHHHHHHHHHHHHH	9.97	24719451
278	Phosphorylation	EIIELRRTVNALEIE HHHHHHHHHCHHHHH	16.21	20068231
307	Phosphorylation	LTESEARYSSQLSQV CCHHHHHHHHHHHHH	21.52	24043423
308	Phosphorylation	TESEARYSSQLSQVQ CHHHHHHHHHHHHHH	13.17	24043423
309	Phosphorylation	ESEARYSSQLSQVQS HHHHHHHHHHHHHHH	26.63	24043423
312	Phosphorylation	ARYSSQLSQVQSLIT HHHHHHHHHHHHHHH	22.22	24043423
316	Phosphorylation	SQLSQVQSLITNVES HHHHHHHHHHHHHHH	23.92	24043423
319	Phosphorylation	SQVQSLITNVESQLA HHHHHHHHHHHHHHH	38.21	24043423
323	Phosphorylation	SLITNVESQLAEIRS HHHHHHHHHHHHHHH	26.64	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KT33B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KT33B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KT33B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KDM1A_HUMAN	KDM1A	physical	23455924
ABI2_HUMAN	ABI2	physical	25416956
K2C79_HUMAN	KRT79	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.