MYH2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYH2_HUMAN
• UniProt AC: Q9UKX2
• Protein Name: Myosin-2
• Gene Name: MYH2
• Organism: Homo sapiens (Human).
• Sequence Length: 1941
• Subcellular Localization: Cytoplasm, myofibril. Thick filaments of the myofibrils.
• Protein Description: Muscle contraction. Required for cytoskeleton organization (By similarity)..
• Protein Sequence: MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSDSELAV ------CCCHHHHHH	54.91	28634298
3	Phosphorylation	-----MSSDSELAVF -----CCCHHHHHHH	57.95	22673903
5	Phosphorylation	---MSSDSELAVFGE ---CCCHHHHHHHHH	36.14	28634298
20	Phosphorylation	AAPFLRKSERERIEA HHHHCCHHHHHHHHH	35.14	26437602
36	Phosphorylation	NRPFDAKTSVFVAEP CCCCCCCCCEEEECC	31.66	27135362
37	Phosphorylation	RPFDAKTSVFVAEPK CCCCCCCCEEEECCC	16.92	27135362
51	Phosphorylation	KESFVKGTIQSREGG CCHHCCCEEEECCCC	15.32	19764811
54	Phosphorylation	FVKGTIQSREGGKVT HCCCEEEECCCCEEE	28.57	19764811
61	Phosphorylation	SREGGKVTVKTEGGA ECCCCEEEEEECCCC	21.55	26437602
64	Phosphorylation	GGKVTVKTEGGATLT CCEEEEEECCCCEEE	35.21	26437602
69	Phosphorylation	VKTEGGATLTVKDDQ EEECCCCEEEECCCE	26.66	26437602
71	Phosphorylation	TEGGATLTVKDDQVF ECCCCEEEECCCEEE	22.58	26437602
95	Phosphorylation	IEDMAMMTHLHEPAV HHHHHHHHCCCCHHH	14.27	26437602
104	Phosphorylation	LHEPAVLYNLKERYA CCCHHHHCCHHHHHH	16.32	26437602
130	"N6,N6,N6-trimethyllysine"	CVTVNPYKWLPVYKP EEEECCCCCCCCCCH	43.44	-
130	Methylation	CVTVNPYKWLPVYKP EEEECCCCCCCCCCH	43.44	-
157	Phosphorylation	EAPPHIFSISDNAYQ CCCCCEEECCCCEEE	22.15	25850435
159	Phosphorylation	PPHIFSISDNAYQFM CCCEEECCCCEEEEE	24.50	25850435
163	Phosphorylation	FSISDNAYQFMLTDR EECCCCEEEEEECCC	14.45	25850435
168	Phosphorylation	NAYQFMLTDRENQSI CEEEEEECCCCCCEE	22.63	-
174	Phosphorylation	LTDRENQSILITGES ECCCCCCEEEEECCC	30.83	26437602
181	Phosphorylation	SILITGESGAGKTVN EEEEECCCCCCCCCC	34.98	26437602
195	Phosphorylation	NTKRVIQYFATIAVT CHHHHHHHEEEEEEC	5.53	25850435
198	Phosphorylation	RVIQYFATIAVTGEK HHHHHEEEEEECCCC	10.28	25850435
202	Phosphorylation	YFATIAVTGEKKKEE HEEEEEECCCCCHHH	30.51	21406692
212	Phosphorylation	KKKEEITSGKIQGTL CCHHHHCCCCCCCCH	43.69	26437602
218	Phosphorylation	TSGKIQGTLEDQIIS CCCCCCCCHHHCHHC	15.59	22673903
237	Ubiquitination	LEAFGNAKTVRNDNS HHHHCCCEEECCCCC	52.10	22817900
244	Phosphorylation	KTVRNDNSSRFGKFI EEECCCCCCCCCEEE	26.25	29514088
245	Phosphorylation	TVRNDNSSRFGKFIR EECCCCCCCCCEEEE	37.57	29514088
249	Ubiquitination	DNSSRFGKFIRIHFG CCCCCCCEEEEEEEC	34.60	-
257	Phosphorylation	FIRIHFGTTGKLASA EEEEEECCCCCCCCC	31.28	26437602
258	Phosphorylation	IRIHFGTTGKLASAD EEEEECCCCCCCCCC	32.47	26437602
263	Phosphorylation	GTTGKLASADIETYL CCCCCCCCCCHHHHH	36.59	22673903
268	Phosphorylation	LASADIETYLLEKSR CCCCCHHHHHHHHCE	21.58	22673903
269	Phosphorylation	ASADIETYLLEKSRV CCCCHHHHHHHHCEE	9.12	22673903
273	Ubiquitination	IETYLLEKSRVVFQL HHHHHHHHCEEEEEE	43.46	29901268
356	Phosphorylation	KVSIYKLTGAVMHYG CEEEEEHHHCHHHHC	20.95	-
362	Phosphorylation	LTGAVMHYGNLKFKQ HHHCHHHHCCCCHHH	6.93	26437602
381	Phosphorylation	EQAEPDGTEVADKAA HHCCCCCCHHHHHHH	34.37	26437602
389	Phosphorylation	EVADKAAYLQSLNSA HHHHHHHHHHHCCHH	15.33	19764811
392	Phosphorylation	DKAAYLQSLNSADLL HHHHHHHHCCHHHHH	27.24	26437602
404	Phosphorylation	DLLKALCYPRVKVGN HHHHHHCCCCEEECC	8.57	26437602
413	Phosphorylation	RVKVGNEYVTKGQTV CEEECCEEECCCCCH	19.88	19764811
415	Phosphorylation	KVGNEYVTKGQTVEQ EECCEEECCCCCHHH	28.67	26437602
416	Acetylation	VGNEYVTKGQTVEQV ECCEEECCCCCHHHH	38.69	30584629
419	Phosphorylation	EYVTKGQTVEQVSNA EEECCCCCHHHHHHH	34.38	26437602
424	Phosphorylation	GQTVEQVSNAVGALA CCCHHHHHHHHHHHH	20.83	26437602
452	Phosphorylation	RINQQLDTKQPRQYF HHHHHCCCCCCCHHH	39.92	26437602
505	Acetylation	VLEQEEYKKEGIEWT EECHHHHHHCCCCEE	47.86	30584611
549	Phosphorylation	MFPKATDTSFKNKLY CCCCCCCCCHHHHHH	31.54	24769528
550	Phosphorylation	FPKATDTSFKNKLYD CCCCCCCCHHHHHHH	36.71	24769528
556	Phosphorylation	TSFKNKLYDQHLGKS CCHHHHHHHHCCCCC	18.37	26437602
563	Phosphorylation	YDQHLGKSANFQKPK HHHCCCCCCCCCCCC	27.01	26437602
594	Phosphorylation	GVVDYNITGWLEKNK CCCCHHCCCHHHHCC	20.76	26437602
607	Phosphorylation	NKDPLNETVVGLYQK CCCCCCHHHHHHHHH	21.30	-
612	Phosphorylation	NETVVGLYQKSAMKT CHHHHHHHHHHHHHH	14.15	26437602
619	Phosphorylation	YQKSAMKTLAQLFSG HHHHHHHHHHHHHCC	17.78	26437602
625	Phosphorylation	KTLAQLFSGAQTAEG HHHHHHHCCCCCCCC	41.64	19764811
629	Phosphorylation	QLFSGAQTAEGEGAG HHHCCCCCCCCCCCC	26.58	26437602
648	Phosphorylation	KGGKKKGSSFQTVSA CCCCCCCCCHHHHHH	36.54	26437602
649	Phosphorylation	GGKKKGSSFQTVSAL CCCCCCCCHHHHHHH	30.00	26437602
652	Phosphorylation	KKGSSFQTVSALFRE CCCCCHHHHHHHHHH	17.89	26437602
666	Phosphorylation	ENLNKLMTNLRSTHP HHHHHHHHHHHHHCC	41.35	19764811
670	Phosphorylation	KLMTNLRSTHPHFVR HHHHHHHHHCCCEEE	33.94	26437602
671	Phosphorylation	LMTNLRSTHPHFVRC HHHHHHHHCCCEEEE	32.75	26437602
684	Phosphorylation	RCIIPNETKTPGAME EEECCCCCCCCCCCH	47.02	26437602
686	Phosphorylation	IIPNETKTPGAMEHE ECCCCCCCCCCCHHH	34.08	26437602
721	Phosphorylation	GFPSRILYADFKQRY CCCCEEEECCHHHHH	11.18	22817900
734	Phosphorylation	RYKVLNASAIPEGQF HHHHHCHHHCCCCCC	26.17	19764811
744	Phosphorylation	PEGQFIDSKKASEKL CCCCCCCCHHHHHHH	31.10	19764811
746	Acetylation	GQFIDSKKASEKLLA CCCCCCHHHHHHHHH	62.18	30584665
748	Phosphorylation	FIDSKKASEKLLASI CCCCHHHHHHHHHHE	44.11	19764811
759	Methylation	LASIDIDHTQYKFGH HHHEECCCCCCCCCC	18.40	-
792	Phosphorylation	DKLAQLITRTQARCR HHHHHHHHHHHHHHH	35.93	26437602
822	Phosphorylation	EAIFCIQYNIRSFMN HHHEEEEEHHHHHCC	7.82	26437602
837	Acetylation	VKHWPWMKLFFKIKP CCCCHHHHHHHHHHH	37.97	19810415
847	Acetylation	FKIKPLLKSAETEKE HHHHHHHHCCHHHHH	56.13	19810425
857	Phosphorylation	ETEKEMATMKEEFQK HHHHHHHHHHHHHHH	27.71	-
877	Acetylation	AKSEAKRKELEEKMV HHHHHHHHHHHHHHH	66.98	11921593
917	Phosphorylation	RCDQLIKTKIQLEAK HHHHHHHHHHHHHHH	26.79	26437602
924	Acetylation	TKIQLEAKIKEVTER HHHHHHHHHHHHHHH	44.96	19820369
929	Phosphorylation	EAKIKEVTERAEDEE HHHHHHHHHHCCCHH	22.35	28787133
943	Phosphorylation	EEINAELTAKKRKLE HHHHHHHHHHHHHHH	28.12	26437602
954	Phosphorylation	RKLEDECSELKKDID HHHHHHHHHHHHCHH	43.87	26437602
957	Acetylation	EDECSELKKDIDDLE HHHHHHHHHCHHHHH	44.33	160689
958	Acetylation	DECSELKKDIDDLEL HHHHHHHHCHHHHHH	72.96	30584641
966	Phosphorylation	DIDDLELTLAKVEKE CHHHHHHHHHHHHHH	18.46	22673903
985	Phosphorylation	ENKVKNLTEEMAGLD HHHHHHHHHHHHCHH	39.01	20068231
994	Phosphorylation	EMAGLDETIAKLTKE HHHCHHHHHHHHHHH	26.38	20068231
999	Phosphorylation	DETIAKLTKEKKALQ HHHHHHHHHHHHHHH	36.13	26437602
1012	Phosphorylation	LQEAHQQTLDDLQAE HHHHHHHHHHHHHHH	26.11	26437602
1025	Phosphorylation	AEEDKVNTLTKAKIK HHHHHHHHHHHHHHH	38.50	19764811
1043	Phosphorylation	QVDDLEGSLEQEKKL HHHHCCCCHHHHHHH	21.25	19764811
1048	Acetylation	EGSLEQEKKLRMDLE CCCHHHHHHHHHHHH	57.72	30584605
1071	Phosphorylation	DLKLAQESIMDIENE HHHHHHHHHHHHHHH	15.90	26437602
1094	Phosphorylation	KKKEFEISNLQSKIE HHHHHHHHHHHHHCC	25.04	26437602
1098	Phosphorylation	FEISNLQSKIEDEQA HHHHHHHHHCCHHHH	38.47	26437602
1112	Acetylation	ALGIQLQKKIKELQA HHHHHHHHHHHHHHH	66.12	30584623
1132	Methylation	EEEIEAERASRAKAE HHHHHHHHHHHHHHH	44.93	16187961
1134	Phosphorylation	EIEAERASRAKAEKQ HHHHHHHHHHHHHHH	38.70	19764811
1143	Phosphorylation	AKAEKQRSDLSRELE HHHHHHHHHHHHHHH	40.17	19764811
1146	Phosphorylation	EKQRSDLSRELEEIS HHHHHHHHHHHHHHH	28.79	19764811
1153	Phosphorylation	SRELEEISERLEEAG HHHHHHHHHHHHHCC	21.68	22673903
1163	Phosphorylation	LEEAGGATSAQIEMN HHHCCCCCHHHHHHH	28.06	22673903
1164	Phosphorylation	EEAGGATSAQIEMNK HHCCCCCHHHHHHHH	20.03	19764811
1188	Phosphorylation	RRDLEEATLQHEATA HHHHHHHHHHHHHHH	30.17	19764811
1194	Phosphorylation	ATLQHEATAATLRKK HHHHHHHHHHHHHHH	17.53	19764811
1197	Phosphorylation	QHEATAATLRKKHAD HHHHHHHHHHHHHHH	25.32	19764811
1205	Phosphorylation	LRKKHADSVAELGEQ HHHHHHHHHHHHHHH	24.82	19764811
1228	Phosphorylation	QKLEKEKSEMKMEID HHHHHHHHHHHHHHH	43.97	28387310
1239	Phosphorylation	MEIDDLASNVETVSK HHHHHHHHCHHHHHH	49.02	19764811
1243	Phosphorylation	DLASNVETVSKAKGN HHHHCHHHHHHHHCC	26.29	28387310
1245	Phosphorylation	ASNVETVSKAKGNLE HHCHHHHHHHHCCHH	34.02	28387310
1257	Phosphorylation	NLEKMCRTLEDQLSE CHHHHHHHHHHHHHH	29.58	26437602
1263	Phosphorylation	RTLEDQLSELKSKEE HHHHHHHHHHHCHHH	34.94	19764811
1267	Phosphorylation	DQLSELKSKEEEQQR HHHHHHHCHHHHHHH	58.90	19764811
1280	Phosphorylation	QRLINDLTAQRGRLQ HHHHHHHHHHHCCCC	24.49	26437602
1288	Phosphorylation	AQRGRLQTESGEFSR HHHCCCCCCCCCHHH	36.39	19764811
1290	Phosphorylation	RGRLQTESGEFSRQL HCCCCCCCCCHHHHC	47.19	26437602
1294	Phosphorylation	QTESGEFSRQLDEKE CCCCCCHHHHCCHHH	18.15	19764811
1305	Phosphorylation	DEKEALVSQLSRGKQ CHHHHHHHHHHHHHH	26.67	19764811
1308	Phosphorylation	EALVSQLSRGKQAFT HHHHHHHHHHHHHHH	31.20	19764811
1315	Phosphorylation	SRGKQAFTQQIEELK HHHHHHHHHHHHHHH	23.68	19764811
1341	Phosphorylation	ALAHALQSSRHDCDL HHHHHHHHCHHHHHH	30.14	26437602
1342	Phosphorylation	LAHALQSSRHDCDLL HHHHHHHCHHHHHHH	22.22	22673903
1353	Phosphorylation	CDLLREQYEEEQESK HHHHHHHHHHHHHHH	22.13	26437602
1359	Phosphorylation	QYEEEQESKAELQRA HHHHHHHHHHHHHHH	36.54	26437602
1368	Phosphorylation	AELQRALSKANTEVA HHHHHHHHHHHHHHH	28.83	19764811
1372	Phosphorylation	RALSKANTEVAQWRT HHHHHHHHHHHHHHH	36.37	26437602
1379	Phosphorylation	TEVAQWRTKYETDAI HHHHHHHHHHHHHHH	34.71	26437602
1381	Phosphorylation	VAQWRTKYETDAIQR HHHHHHHHHHHHHHH	24.37	19764811
1383	Phosphorylation	QWRTKYETDAIQRTE HHHHHHHHHHHHHHH	27.86	19764811
1389	Phosphorylation	ETDAIQRTEELEEAK HHHHHHHHHHHHHHH	19.89	20068231
1396	Acetylation	TEELEEAKKKLAQRL HHHHHHHHHHHHHHH	54.44	19862823
1397	Acetylation	EELEEAKKKLAQRLQ HHHHHHHHHHHHHHH	61.13	30584617
1398	Acetylation	ELEEAKKKLAQRLQA HHHHHHHHHHHHHHH	48.63	30584653
1419	Phosphorylation	AVNAKCASLEKTKQR HHHHHHHCHHHHHHH	46.67	24719451
1423	Phosphorylation	KCASLEKTKQRLQNE HHHCHHHHHHHHHHH	24.04	24719451
1441	Phosphorylation	LMLDVERTNAACAAL HHHHHHHHHHHHHHH	18.72	26437602
1450	Acetylation	AACAALDKKQRNFDK HHHHHHHHHHHCHHH	52.21	30584647
1469	Phosphorylation	WKQKCEETHAELEAS HHHHHHHHHHHHHHH	12.23	24769528
1476	Phosphorylation	THAELEASQKEARSL HHHHHHHHHHHHHHH	32.20	-
1482	Phosphorylation	ASQKEARSLGTELFK HHHHHHHHHCHHHHH	37.89	19764811
1485	Phosphorylation	KEARSLGTELFKIKN HHHHHHCHHHHHHHH	34.50	19764811
1494	Phosphorylation	LFKIKNAYEESLDQL HHHHHHHHHHHHHHH	29.62	19764811
1497	Phosphorylation	IKNAYEESLDQLETL HHHHHHHHHHHHHHH	25.88	-
1503	Phosphorylation	ESLDQLETLKRENKN HHHHHHHHHHHHCHH	46.28	26437602
1516	Phosphorylation	KNLQQEISDLTEQIA HHHHHHHHHHHHHHH	26.30	22777824
1519	Phosphorylation	QQEISDLTEQIAEGG HHHHHHHHHHHHHHH	30.73	26437602
1556	Phosphorylation	ALEEAEASLEHEEGK HHHHHHHHHCCCCCC	26.29	26437602
1576	Phosphorylation	LELNQVKSEVDRKIA HHHHHHHHHHHHHHH	43.95	19764811
1602	Phosphorylation	NHIRIVESMQSTLDA HCHHHHHHHHHHHHH	15.95	26437602
1605	Phosphorylation	RIVESMQSTLDAEIR HHHHHHHHHHHHHHH	23.46	19764811
1606	Phosphorylation	IVESMQSTLDAEIRS HHHHHHHHHHHHHHC	16.27	19764811
1613	Phosphorylation	TLDAEIRSRNDAIRL HHHHHHHCHHHHHHH	40.89	24719451
1649	Phosphorylation	AAEALRNYRNTQGIL HHHHHHHHHHCCCHH	9.98	26437602
1652	Phosphorylation	ALRNYRNTQGILKDT HHHHHHHCCCHHHHC	21.12	26437602
1659	Phosphorylation	TQGILKDTQIHLDDA CCCHHHHCEECHHHH	28.03	26437602
1669	Phosphorylation	HLDDALRSQEDLKEQ CHHHHHHCHHHHHHH	38.48	26437602
1697	Phosphorylation	EIEELRATLEQTERS HHHHHHHHHHHHHHH	25.13	26437602
1701	Phosphorylation	LRATLEQTERSRKIA HHHHHHHHHHHHHHH	24.80	26437602
1704	Phosphorylation	TLEQTERSRKIAEQE HHHHHHHHHHHHHHH	31.52	26437602
1716	Phosphorylation	EQELLDASERVQLLH HHHHHCHHHHHHHHH	26.13	20068231
1724	Phosphorylation	ERVQLLHTQNTSLIN HHHHHHHHCCCCCCC	24.39	19764811
1727	Phosphorylation	QLLHTQNTSLINTKK HHHHHCCCCCCCCHH	18.32	19764811
1728	Phosphorylation	LLHTQNTSLINTKKK HHHHCCCCCCCCHHH	34.50	22777824
1732	Phosphorylation	QNTSLINTKKKLETD CCCCCCCCHHHHHHH	36.93	19764811
1733	Acetylation	NTSLINTKKKLETDI CCCCCCCHHHHHHHH	43.34	19862843
1738	Phosphorylation	NTKKKLETDISQMQG CCHHHHHHHHHHHHH	49.41	20068231
1741	Phosphorylation	KKLETDISQMQGEME HHHHHHHHHHHHHHH	23.55	20068231
1766	Phosphorylation	EKAKKAITDAAMMAE HHHHHHHHHHHHHHH	25.17	30576142
1776	Acetylation	AMMAEELKKEQDTSA HHHHHHHHHHHCCHH	58.50	30584659
1777	Ubiquitination	MMAEELKKEQDTSAH HHHHHHHHHHCCHHH	73.55	30230243
1781	Phosphorylation	ELKKEQDTSAHLERM HHHHHHCCHHHHHHH	27.75	26437602
1782	Phosphorylation	LKKEQDTSAHLERMK HHHHHCCHHHHHHHH	23.21	26437602
1790	Acetylation	AHLERMKKNMEQTVK HHHHHHHHHHHHHHH	52.78	7704583
1795	Phosphorylation	MKKNMEQTVKDLQLR HHHHHHHHHHHHHHH	19.06	26437602
1797	Acetylation	KNMEQTVKDLQLRLD HHHHHHHHHHHHHHH	56.99	7704591
1812	Ubiquitination	EAEQLALKGGKKQIQ HHHHHHHHCCHHHHH	61.07	22817900
1815	Ubiquitination	QLALKGGKKQIQKLE HHHHHCCHHHHHHHH	50.61	22817900
1816	Ubiquitination	LALKGGKKQIQKLEA HHHHCCHHHHHHHHH	56.77	22817900
1820	Ubiquitination	GGKKQIQKLEARVRE CCHHHHHHHHHHHHH	50.34	22817900
1834	Phosphorylation	ELEGEVESEQKRNAE HHHCCCCHHHHHCHH	50.97	19764811
1837	Acetylation	GEVESEQKRNAEAVK CCCCHHHHHCHHHHH	43.50	19832403
1857	Phosphorylation	ERRVKELTYQTEEDR HHHHHHHHCCCHHHH	18.06	19764811
1858	Phosphorylation	RRVKELTYQTEEDRK HHHHHHHCCCHHHHH	26.51	26437602
1860	Phosphorylation	VKELTYQTEEDRKNI HHHHHCCCHHHHHHH	30.81	26437602
1865	Acetylation	YQTEEDRKNILRLQD CCCHHHHHHHHHHHH	61.74	30584635
1895	Phosphorylation	AEEAEEQSNTNLAKF HHHHHHHHCCCHHHH	49.23	19764811
1897	Phosphorylation	EAEEQSNTNLAKFRK HHHHHHCCCHHHHHH	36.54	19764811
1921	Phosphorylation	ERADIAESQVNKLRV HHHHHHHHHHHHHHH	30.33	19764811
1930	Phosphorylation	VNKLRVKSREVHTKV HHHHHHCCCCHHHHH	30.71	26437602

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1921	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYH2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYH2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ACTN1_HUMAN	ACTN1	physical	26344197
ACTN2_HUMAN	ACTN2	physical	26344197
ACTN4_HUMAN	ACTN4	physical	26344197
TPM1_HUMAN	TPM1	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 605637: Myopathy, proximal, and ophthalmoplegia (MYPOP)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.