ANK3_HUMAN - dbPTM
ANK3_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ANK3_HUMAN
UniProt AC Q12955
Protein Name Ankyrin-3 {ECO:0000303|PubMed:7836469}
Gene Name ANK3 {ECO:0000312|HGNC:HGNC:494}
Organism Homo sapiens (Human).
Sequence Length 4377
Subcellular Localization Cytoplasm, cytoskeleton . Cell projection, axon. Cell membrane, sarcolemma . Cell junction, synapse, postsynaptic cell membrane. Lysosome. In skeletal muscle, localized at costameres and neuromuscular junctions. In macrophages, associated with lysoso
Protein Description In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption. [PubMed: 23903368; Isoform 5: May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin.]
Protein Sequence MAHAASQLKKNRDLEINAEEEPEKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLDMSDDEVRKANAPEMLSDGEYISDVEEGEDAMTGDTDKYLGPQDLKELGDDSLPAEGYMGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKETESDQDDEIEKTDRRQSFASLALRKRYSYLTEPGMIERSTGATRSLPTTYSYKPFFSTRPYQSWTTAPITVPGPAKSGFTSLSSSSSNTPSASPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAVTEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIITSAAPLISSPLKSVVSPVKSAVDVISSAKITMASSLSSPVKQMPGHAEVALVNGSISPLKYPSSSTLINGCKATATLQEKISSATNSVSSVVSAATDTVEKVFSTTTAMPFSPLRSYVSAAPSAFQSLRTPSASALYTSLGSSISATTSSVTSSIITVPVYSVVNVLPEPALKKLPDSNSFTKSAAALLSPIKTLTTETHPQPHFSRTSSPVKSSLFLAPSALKLSTPSSLSSSQEILKDVAEMKEDLMRMTAILQTDVPEEKPFQPELPKEGRIDDEEPFKIVEKVKEDLVKVSEILKKDVCVDNKGSPKSPKSDKGHSPEDDWIEFSSEEIREARQQAAASQSPSLPERVQVKAKAASEKDYNLTKVIDYLTNDIGSSSLTNLKYKFEDAKKDGEERQKRVLKPAIALQEHKLKMPPASMRTSTSEKELCKMADSFFGTDTILESPDDFSQHDQDKSPLSDSGFETRSEKTPSAPQSAESTGPKPLFHEVPIPPVITETRTEVVHVIRSYDPSAGDVPQTQPEEPVSPKPSPTFMELEPKPTTSSIKEKVKAFQMKASSEEDDHNRVLSKGMRVKEETHITTTTRMVYHSPPGGEGASERIEETMSVHDIMKAFQSGRDPSKELAGLFEHKSAVSPDVHKSAAETSAQHAEKDNQMKPKLERIIEVHIEKGNQAEPTEVIIRETKKHPEKEMYVYQKDLSRGDINLKDFLPEKHDAFPCSEEQGQQEEEELTAEESLPSYLESSRVNTPVSQEEDSRPSSAQLISDDSYKTLKLLSQHSIEYHDDELSELRGESYRFAEKMLLSEKLDVSHSDTEESVTDHAGPPSSELQGSDKRSREKIATAPKKEILSKIYKDVSENGVGKVSKDEHFDKVTVLHYSGNVSSPKHAMWMRFTEDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFRDKTEKLNDELQSPEKKARPKNGKEYSSQSPTSSSPEKVLLTELLASNDEWVKARQHGPDGQGFPKAEEKAPSLPSSPEKMVLSQQTEDSKSTVEAKGSISQSKAPDGPQSGFQLKQSKLSSIRLKFEQGTHAKSKDMSQEDRKSDGQSRIPVKKIQESKLPVYQVFAREKQQKAIDLPDESVSVQKDFMVLKTKDEHAQSNEIVVNDSGSDNVKKQRTEMSSKAMPDSFSEQQAKDLACHITSDLATRGPWDKKVFRTWESSGATNNKSQKEKLSHVLVHDVRENHIGHPESKSVDQKNEFMSVTERERKLLTNGSLSEIKEMTVKSPSKKVLYREYVVKEGDHPGGLLDQPSRRSESSAVSHIPVRVADERRMLSSNIPDGFCEQSAFPKHELSQKLSQSSMSKETVETQHFNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETETSPTKSPDSLEFSPGKESPSSDVFDHSPIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGKQYEKEIQQGGVKKIISQECKTVQETRGTFYTTRQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEEVSYEFTSKTPDSLIAYIPGKPSPIPEVSEESEEEEQAKSTSLKQTTVEETAVEREMPNDVSKDSNQRPKNNRVAYIEFPPPPPLDADQIESDKKHHYLPEKEVDMIEVNLQDEHDKYQLAEPVIRVQPPSPVPPGADVSDSSDDESIYQPVPVKKYTFKLKEVDDEQKEKPKASAEKASNQKELESNGSGKDNEFGLGLDSPQNEIAQNGNNDQSITECSIATTAEFSHDTDATEIDSLDGYDLQDEDDGLTESDSKLPIQAMEIKKDIWNTEGILKPADRSFSQSKLEVIEEEGKVGPDEDKPPSKSSSSEKTPDKTDQKSGAQFFTLEGRHPDRSVFPDTYFSYKVDEEFATPFKTVATKGLDFDPWSNNRGDDEVFDSKSREDETKPFGLAVEDRSPATTPDTTPARTPTDESTPTSEPNPFPFHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHTSEGKSGDQGEGDKSMVTATPQPQSGDTTVETNLERNVETPTVEPNPSIPTSGECQEGTSSSGSLEKSAAATNTSKVDPKLRTPIKMGISASTMTMKKEGPGEITDKIEAVMTSCQGLENETITMISNTANSQMGVRPHEKHDFQKDNFNNNNNLDSSTIQTDNIMSNIVLTEHSAPTCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKDTFPPNHMSNTKASKMKQVSQSEKTKALTTSSCVDVKSRIPVKNTHRDNIIAVRKACATQKQGQPEKGKAKQLPSKLPVKVRSTCVTTTTTTATTTTTTTTTTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKMQSELSDEEESTSRNTSLSETSRGGQPSVTTKSARDKKTEAAPLKSKSEKAGSEKRSSRRTGPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETSSGNLESCAQARRVTGGLLDRLDDSPDQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYFPESQNDVGKQSTKETLKPKIHGSGHVEEPASPLAAYQKSLEETSKLIIEETKPCVPVSMKKMSRTSPADGKPRLSLHEEEGSSGSEQKQGEGFKVKTKKEIRHVEKKSHS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
3 (in isoform 5)Phosphorylation-33.4223090842
4 (in isoform 5)Phosphorylation-18.8323090842
6 (in isoform 5)Phosphorylation-36.5123090842
7 (in isoform 5)Phosphorylation-53.2023090842
8 (in isoform 5)Phosphorylation-8.7023090842
9AcetylationAHAASQLKKNRDLEI
CHHHHHHHHCCCCCC
40.1230585979
12 (in isoform 5)Phosphorylation-59.7923090842
14 (in isoform 6)Phosphorylation-6.8526356563
15 (in isoform 5)Phosphorylation-38.1924719451
17 (in isoform 6)Phosphorylation-31.7426356563
22 (in isoform 4)Phosphorylation-63.0825849741
24 (in isoform 5)Phosphorylation-69.4623090842
26 (in isoform 5)Phosphorylation-51.5923090842
27 (in isoform 4)Phosphorylation-57.55-
27 (in isoform 5)Phosphorylation-57.5523090842
28 (in isoform 4)Phosphorylation-44.52-
29 (in isoform 5)Phosphorylation-38.8323090842
30 (in isoform 5)Phosphorylation-55.2123090842
33 (in isoform 5)Phosphorylation-52.3525849741
39PhosphorylationSRDRKKKSDANASYL
HHHHHHHHHHCHHHH
51.3327794612
44PhosphorylationKKSDANASYLRAARA
HHHHHCHHHHHHHHH
25.2228857561
45PhosphorylationKSDANASYLRAARAG
HHHHCHHHHHHHHHH
9.5927732954
60PhosphorylationHLEKALDYIKNGVDI
CHHHHHHHHHCCCCE
18.0446163537
115PhosphorylationNTALHIASLAGQAEV
CHHHHHHHHCCCCEE
20.3946163295
245PhosphorylationPLHIAAHYGNINVAT
HHHHHHHHCCCCHHH
13.7230835397
276PhosphorylationITPLHVASKRGNANM
CCCCHHHCCCCCCCH
23.0728857561
311PhosphorylationPLHCGARSGHEQVVE
CCCCCCCCCHHHHHH
43.9228857561
409AcetylationTPLHIACKKNRIKVM
CHHHHHHHCCHHHHH
44.0230585965
460 (in isoform 7)Phosphorylation-57.9726471730
468PhosphorylationTTNVRGETALHMAAR
CCCCCCHHHHHHHHH
37.0328857561
468 (in isoform 7)Phosphorylation-37.0328355574
477 (in isoform 7)Phosphorylation-25.7626471730
480 (in isoform 7)Phosphorylation-33.3926471730
484PhosphorylationGQAEVVRYLVQDGAQ
CCHHHHHHHHHCCCE
10.3018083107
501PhosphorylationAKAKDDQTPLHISAR
EECCCCCCCHHHHHC
34.5128857561
506PhosphorylationDQTPLHISARLGKAD
CCCCHHHHHCCCHHH
9.1528857561
524PhosphorylationQLLQQGASPNAATTS
HHHHCCCCCCCCCCC
26.0530458941
529PhosphorylationGASPNAATTSGYTPL
CCCCCCCCCCCCCCC
21.0528152594
530PhosphorylationASPNAATTSGYTPLH
CCCCCCCCCCCCCCE
18.5428152594
531PhosphorylationSPNAATTSGYTPLHL
CCCCCCCCCCCCCEE
26.0024853685
533PhosphorylationNAATTSGYTPLHLSA
CCCCCCCCCCCEEEC
12.6421082442
534PhosphorylationAATTSGYTPLHLSAR
CCCCCCCCCCEEECC
23.9325884760
539PhosphorylationGYTPLHLSAREGHED
CCCCCEEECCCCCHH
17.9628152594
575PhosphorylationPLHVAAKYGKLEVAN
HHHHHHHHCCHHHHH
18.1169102643
584 (in isoform 6)Phosphorylation-4.8325849741
594 (in isoform 6)Phosphorylation-33.0729978859
595 (in isoform 6)Phosphorylation-26.7825849741
596 (in isoform 6)Phosphorylation-36.3029978859
598 (in isoform 6)Phosphorylation-36.7429978859
603 (in isoform 6)Phosphorylation-14.3622617229
606 (in isoform 6)Phosphorylation-10.7322617229
611 (in isoform 6)Phosphorylation-38.4123090842
623PhosphorylationLLLDQGASPHAAAKN
EEECCCCCHHHHHHC
24.8422617229
632PhosphorylationHAAAKNGYTPLHIAA
HHHHHCCCCHHHHHH
17.9925884760
648PhosphorylationKNQMDIATTLLEYGA
HCCCCHHHHHHHHCC
20.5020363803
653PhosphorylationIATTLLEYGADANAV
HHHHHHHHCCCCCCC
19.9920363803
731PhosphorylationDAQTKMGYTPLHVGC
CCCCCCCCCCCEEEE
11.167117539
732PhosphorylationAQTKMGYTPLHVGCH
CCCCCCCCCCEEEEC
17.4046163525
740PhosphorylationPLHVGCHYGNIKIVN
CCEEEECCCCHHHHH
18.8846163543
747 (in isoform 6)Phosphorylation-25.89-
753PhosphorylationVNFLLQHSAKVNAKT
HHHHHHHCCCCCCCC
19.4728857561
756 (in isoform 6)Phosphorylation-9.3526657352
760 (in isoform 6)Phosphorylation-27.6028348404
762 (in isoform 6)Phosphorylation-54.6726657352
765 (in isoform 6)Phosphorylation-22.2925849741
771 (in isoform 6)Phosphorylation-8.8225850435
778 (in isoform 6)Phosphorylation-2.2927732954
786 (in isoform 6)Phosphorylation-28.9128102081
791 (in isoform 6)Phosphorylation-49.5625849741
795 (in isoform 6)Phosphorylation-32.5328102081
808PhosphorylationGIARRLGYISVVDTL
HHHHHHCCEEEEEEE
8.4627251275
810PhosphorylationARRLGYISVVDTLKI
HHHHCCEEEEEEEEE
13.9628857561
814PhosphorylationGYISVVDTLKIVTEE
CCEEEEEEEEEECCC
20.5222673903
819PhosphorylationVDTLKIVTEETMTTT
EEEEEEECCCCCCCC
31.4168712505
822PhosphorylationLKIVTEETMTTTTVT
EEEECCCCCCCCCCC
17.3768712507
824PhosphorylationIVTEETMTTTTVTEK
EECCCCCCCCCCCHH
28.5425262027
825PhosphorylationVTEETMTTTTVTEKH
ECCCCCCCCCCCHHH
15.0625262027
826PhosphorylationTEETMTTTTVTEKHK
CCCCCCCCCCCHHHC
15.3125262027
827PhosphorylationEETMTTTTVTEKHKM
CCCCCCCCCCHHHCC
24.2825262027
829PhosphorylationTMTTTTVTEKHKMNV
CCCCCCCCHHHCCCC
36.9125262027
839PhosphorylationHKMNVPETMNEVLDM
HCCCCCHHHHHHHCC
21.1623927012
844 (in isoform 4)Phosphorylation-3.5923927012
847PhosphorylationMNEVLDMSDDEVRKA
HHHHHCCCHHHHHHC
41.3923927012
848 (in isoform 4)Phosphorylation-49.8326657352
850 (in isoform 4)Phosphorylation-49.5725849741
861PhosphorylationANAPEMLSDGEYISD
CCCCHHCCCCCCCCC
42.119459507
861 (in isoform 4)Phosphorylation-42.11-
865PhosphorylationEMLSDGEYISDVEEG
HHCCCCCCCCCCCCC
15.9722199227
867PhosphorylationLSDGEYISDVEEGED
CCCCCCCCCCCCCCC
34.405022405
873 (in isoform 4)Phosphorylation-45.9728348404
877PhosphorylationEEGEDAMTGDTDKYL
CCCCCCCCCCCCCCC
33.3627251275
880PhosphorylationEDAMTGDTDKYLGPQ
CCCCCCCCCCCCCHH
35.4223909892
881 (in isoform 4)Phosphorylation-42.2026356563
883PhosphorylationMTGDTDKYLGPQDLK
CCCCCCCCCCHHHHH
21.5017117922
884 (in isoform 4)Phosphorylation-11.2626356563
896PhosphorylationLKELGDDSLPAEGYM
HHHHCCCCCCCCCCC
40.7841301665
902PhosphorylationDSLPAEGYMGFSLGA
CCCCCCCCCCCCCCC
5.8868702885
906PhosphorylationAEGYMGFSLGARSAS
CCCCCCCCCCCCCCC
21.8430576142
911PhosphorylationGFSLGARSASLRSFS
CCCCCCCCCCCCCCC
22.9829743597
913PhosphorylationSLGARSASLRSFSSD
CCCCCCCCCCCCCCC
26.0928355574
916PhosphorylationARSASLRSFSSDRSY
CCCCCCCCCCCCCCE
34.4728355574
918PhosphorylationSASLRSFSSDRSYTL
CCCCCCCCCCCCEEC
32.3522617229
919PhosphorylationASLRSFSSDRSYTLN
CCCCCCCCCCCEECC
34.7223898821
921MethylationLRSFSSDRSYTLNRS
CCCCCCCCCEECCCC
33.25-
922PhosphorylationRSFSSDRSYTLNRSS
CCCCCCCCEECCCCH
27.7122617229
923PhosphorylationSFSSDRSYTLNRSSY
CCCCCCCEECCCCHH
19.0125219547
924PhosphorylationFSSDRSYTLNRSSYA
CCCCCCEECCCCHHC
20.8525219547
928PhosphorylationRSYTLNRSSYARDSM
CCEECCCCHHCCHHC
26.9923898821
929PhosphorylationSYTLNRSSYARDSMM
CEECCCCHHCCHHCC
21.4123898821
930PhosphorylationYTLNRSSYARDSMMI
EECCCCHHCCHHCCE
13.6024245541
934PhosphorylationRSSYARDSMMIEELL
CCHHCCHHCCEEEHH
12.5127732954
950PhosphorylationPSKEQHLTFTREFDS
CCHHHCCEEEEECCC
22.3426437602
957PhosphorylationTFTREFDSDSLRHYS
EEEEECCCCCCHHCC
34.1325850435
959PhosphorylationTREFDSDSLRHYSWA
EEECCCCCCHHCCEE
31.1229255136
964PhosphorylationSDSLRHYSWAADTLD
CCCCHHCCEEHHHCC
12.2430835391
1044 (in isoform 7)Phosphorylation-31.0525849741
1113PhosphorylationGMDEELDSPEELGKK
CCCCCCCCHHHHCCH
47.004112825
1127PhosphorylationKRICRIITKDFPQYF
HHHHHHHCCCCHHHH
23.3827282143
1128AcetylationRICRIITKDFPQYFA
HHHHHHCCCCHHHHH
47.14129917
1133PhosphorylationITKDFPQYFAVVSRI
HCCCCHHHHHHHHHH
8.1727282143
1326PhosphorylationKMNDPVESSLRCFCM
CCCCCCHHCEEEEEE
34.6021406692
1327PhosphorylationMNDPVESSLRCFCMT
CCCCCHHCEEEEEEC
13.3121406692
1366PhosphorylationVLEGKPIYVDCYGNL
EECCCCEEEECCCCE
9.9630458947
1404PhosphorylationFSIKIRDTSQEPCGR
EEEEEECCCCCCCCC
23.5925159151
1405PhosphorylationSIKIRDTSQEPCGRL
EEEEECCCCCCCCCE
36.5125159151
1413PhosphorylationQEPCGRLSFLKEPKT
CCCCCCEEECCCCCC
27.4624719451
1443PhosphorylationLPAHKKETESDQDDE
ECCCCCCCCCCCCCH
50.0621406692
1444 (in isoform 5)Phosphorylation-54.1025849741
1444PhosphorylationPAHKKETESDQDDEI
CCCCCCCCCCCCCHH
54.1018220336
1445PhosphorylationAHKKETESDQDDEIE
CCCCCCCCCCCCHHH
48.2520068231
1451 (in isoform 4)Phosphorylation-9.4125849741
1454PhosphorylationQDDEIEKTDRRQSFA
CCCHHHHHHHHHHHH
23.1936013255
1454 (in isoform 5)Phosphorylation-23.1929978859
1455 (in isoform 5)Phosphorylation-55.6325849741
1456 (in isoform 5)Phosphorylation-43.7129978859
1458 (in isoform 5)Phosphorylation-43.7429978859
1459PhosphorylationEKTDRRQSFASLALR
HHHHHHHHHHHHHHH
22.4429255136
1461 (in isoform 4)Phosphorylation-14.6429978859
1462PhosphorylationDRRQSFASLALRKRY
HHHHHHHHHHHHHHH
16.5030266825
1462 (in isoform 4)Phosphorylation-16.5025849741
1463 (in isoform 4)Phosphorylation-4.7029978859
1463 (in isoform 5)Phosphorylation-4.7022617229
1465 (in isoform 4)Phosphorylation-8.8829978859
1466 (in isoform 5)Phosphorylation-18.7922617229
1469PhosphorylationSLALRKRYSYLTEPG
HHHHHHHHHHHCCCC
12.52-
1470PhosphorylationLALRKRYSYLTEPGM
HHHHHHHHHHCCCCC
20.079299899
1470 (in isoform 4)Phosphorylation-20.0722617229
1471PhosphorylationALRKRYSYLTEPGMI
HHHHHHHHHCCCCCE
14.54-
1471 (in isoform 5)Phosphorylation-14.5423090842
1473PhosphorylationRKRYSYLTEPGMIER
HHHHHHHCCCCCEEC
31.72-
1473 (in isoform 4)Phosphorylation-31.7222617229
1478 (in isoform 4)Phosphorylation-5.0223090842
1481PhosphorylationEPGMIERSTGATRSL
CCCCEECCCCCCCCC
20.5730576142
1490PhosphorylationGATRSLPTTYSYKPF
CCCCCCCCCCCCCCC
43.5930576142
1491O-linked_GlycosylationATRSLPTTYSYKPFF
CCCCCCCCCCCCCCC
14.4528411811
1491PhosphorylationATRSLPTTYSYKPFF
CCCCCCCCCCCCCCC
14.4527251275
1492PhosphorylationTRSLPTTYSYKPFFS
CCCCCCCCCCCCCCC
16.6930576142
1493PhosphorylationRSLPTTYSYKPFFST
CCCCCCCCCCCCCCC
25.2927251275
1494PhosphorylationSLPTTYSYKPFFSTR
CCCCCCCCCCCCCCC
16.5630576142
1499PhosphorylationYSYKPFFSTRPYQSW
CCCCCCCCCCCCCCC
24.7227251275
1500PhosphorylationSYKPFFSTRPYQSWT
CCCCCCCCCCCCCCE
30.4327251275
1503PhosphorylationPFFSTRPYQSWTTAP
CCCCCCCCCCCEECC
16.3430576142
1508PhosphorylationRPYQSWTTAPITVPG
CCCCCCEECCEECCC
24.9530576142
1512O-linked_GlycosylationSWTTAPITVPGPAKS
CCEECCEECCCCCCC
21.4228411811
1522O-linked_GlycosylationGPAKSGFTSLSSSSS
CCCCCCCCCCCCCCC
32.0828411811
1526O-linked_GlycosylationSGFTSLSSSSSNTPS
CCCCCCCCCCCCCCC
39.2628411811
1527O-linked_GlycosylationGFTSLSSSSSNTPSA
CCCCCCCCCCCCCCC
34.1228411811
1542PhosphorylationSPLKSIWSVSTPSPI
CCCCCCEECCCCCCC
12.4327732954
1544O-linked_GlycosylationLKSIWSVSTPSPIKS
CCCCEECCCCCCCCC
29.1428411811
1544PhosphorylationLKSIWSVSTPSPIKS
CCCCEECCCCCCCCC
29.1427732954
1545PhosphorylationKSIWSVSTPSPIKST
CCCEECCCCCCCCCC
26.1527732954
1547PhosphorylationIWSVSTPSPIKSTLG
CEECCCCCCCCCCCC
39.0727732954
1551O-linked_GlycosylationSTPSPIKSTLGASTT
CCCCCCCCCCCCCCC
29.5928411811
1551PhosphorylationSTPSPIKSTLGASTT
CCCCCCCCCCCCCCC
29.5946163409
1552O-linked_GlycosylationTPSPIKSTLGASTTS
CCCCCCCCCCCCCCC
24.9828411811
1552PhosphorylationTPSPIKSTLGASTTS
CCCCCCCCCCCCCCC
24.9846163477
1556O-linked_GlycosylationIKSTLGASTTSSVKS
CCCCCCCCCCCCCCC
30.3528411811
1556PhosphorylationIKSTLGASTTSSVKS
CCCCCCCCCCCCCCC
30.3530815251
1557O-linked_GlycosylationKSTLGASTTSSVKSI
CCCCCCCCCCCCCCH
30.1128411811
1558O-linked_GlycosylationSTLGASTTSSVKSIS
CCCCCCCCCCCCCHH
19.2628411811
1558PhosphorylationSTLGASTTSSVKSIS
CCCCCCCCCCCCCHH
19.2625690035
1559O-linked_GlycosylationTLGASTTSSVKSISD
CCCCCCCCCCCCHHH
32.9728411811
1559PhosphorylationTLGASTTSSVKSISD
CCCCCCCCCCCCHHH
32.9730815255
1560PhosphorylationLGASTTSSVKSISDV
CCCCCCCCCCCHHHC
31.3230815259
1563O-linked_GlycosylationSTTSSVKSISDVASP
CCCCCCCCHHHCCCC
25.7628411811
1563PhosphorylationSTTSSVKSISDVASP
CCCCCCCCHHHCCCC
25.7622210691
1565O-linked_GlycosylationTSSVKSISDVASPIR
CCCCCCHHHCCCCHH
32.8828411811
1565PhosphorylationTSSVKSISDVASPIR
CCCCCCHHHCCCCHH
32.8827732954
1569PhosphorylationKSISDVASPIRSFRT
CCHHHCCCCHHHHCC
22.2527732954
1573PhosphorylationDVASPIRSFRTMSSP
HCCCCHHHHCCCCCC
21.5730815263
1578PhosphorylationIRSFRTMSSPIKTVV
HHHHCCCCCCCEEEE
32.1422210691
1586O-linked_GlycosylationSPIKTVVSQSPYNIQ
CCCEEEEECCCCEEE
22.1728411811
1586PhosphorylationSPIKTVVSQSPYNIQ
CCCEEEEECCCCEEE
22.1723612710
1588PhosphorylationIKTVVSQSPYNIQVS
CEEEEECCCCEEEEC
23.1123612710
1590PhosphorylationTVVSQSPYNIQVSSG
EEEECCCCEEEECCC
30.0923612710
1595O-linked_GlycosylationSPYNIQVSSGTLARA
CCCEEEECCCCCCCC
13.4828411811
1595PhosphorylationSPYNIQVSSGTLARA
CCCEEEECCCCCCCC
13.4823612710
1596PhosphorylationPYNIQVSSGTLARAP
CCEEEECCCCCCCCC
36.6223612710
1598O-linked_GlycosylationNIQVSSGTLARAPAV
EEEECCCCCCCCCCC
21.1328411811
1598PhosphorylationNIQVSSGTLARAPAV
EEEECCCCCCCCCCC
21.1323612710
1606O-linked_GlycosylationLARAPAVTEATPLKG
CCCCCCCCCCCCCCC
23.2428411811
1607 (in isoform 5)Phosphorylation-43.90-
1614 (in isoform 4)Phosphorylation-4.52-
1616 (in isoform 5)Phosphorylation-36.0326657352
1620 (in isoform 5)Phosphorylation-6.6528348404
1622PhosphorylationASNSTFSSRTSPVTT
CCCCCCCCCCCCCCC
35.07-
1622 (in isoform 5)Phosphorylation-35.0726657352
1623 (in isoform 4)Phosphorylation-37.7226657352
1624O-linked_GlycosylationNSTFSSRTSPVTTAG
CCCCCCCCCCCCCCC
39.058516879
1624PhosphorylationNSTFSSRTSPVTTAG
CCCCCCCCCCCCCCC
39.0527732954
1625O-linked_GlycosylationSTFSSRTSPVTTAGS
CCCCCCCCCCCCCCH
19.1028411811
1625PhosphorylationSTFSSRTSPVTTAGS
CCCCCCCCCCCCCCH
19.1027732954
1625 (in isoform 5)Phosphorylation-19.1025849741
1627 (in isoform 4)Phosphorylation-8.1228348404
1628O-linked_GlycosylationSSRTSPVTTAGSLLE
CCCCCCCCCCCHHHH
17.828516887
1629O-linked_GlycosylationSRTSPVTTAGSLLER
CCCCCCCCCCHHHHH
29.298516871
1629 (in isoform 4)Phosphorylation-29.2926657352
1631 (in isoform 5)Phosphorylation-19.4125850435
1632O-linked_GlycosylationSPVTTAGSLLERSSI
CCCCCCCHHHHHCCC
27.588516855
1632 (in isoform 4)Phosphorylation-27.5825849741
1637PhosphorylationAGSLLERSSITMTPP
CCHHHHHCCCCCCCC
19.4029978859
1638PhosphorylationGSLLERSSITMTPPA
CHHHHHCCCCCCCCC
28.4429978859
1638 (in isoform 4)Phosphorylation-28.4425850435
1638 (in isoform 5)Phosphorylation-28.4427732954
1640O-linked_GlycosylationLLERSSITMTPPASP
HHHHCCCCCCCCCCC
19.5528411811
1640PhosphorylationLLERSSITMTPPASP
HHHHCCCCCCCCCCC
19.5529978859
1642PhosphorylationERSSITMTPPASPKS
HHCCCCCCCCCCCCC
19.9236752061
1645 (in isoform 4)Phosphorylation-39.4027732954
1646PhosphorylationITMTPPASPKSNINM
CCCCCCCCCCCCCCC
38.3429978859
1646 (in isoform 5)Phosphorylation-38.3428102081
1649PhosphorylationTPPASPKSNINMYSS
CCCCCCCCCCCCCCC
46.4529978859
1651 (in isoform 5)Phosphorylation-3.9625849741
1653 (in isoform 4)Phosphorylation-2.8028102081
1654PhosphorylationPKSNINMYSSSLPFK
CCCCCCCCCCCCCHH
10.8325884760
1655O-linked_GlycosylationKSNINMYSSSLPFKS
CCCCCCCCCCCCHHH
11.5928411811
1655PhosphorylationKSNINMYSSSLPFKS
CCCCCCCCCCCCHHH
11.5929978859
1655 (in isoform 5)Phosphorylation-11.5928102081
1656PhosphorylationSNINMYSSSLPFKSI
CCCCCCCCCCCHHHH
20.5729978859
1657O-linked_GlycosylationNINMYSSSLPFKSII
CCCCCCCCCCHHHHH
33.8428411811
1657PhosphorylationNINMYSSSLPFKSII
CCCCCCCCCCHHHHH
33.8429978859
1658 (in isoform 4)Phosphorylation-6.6325849741
1661AcetylationYSSSLPFKSIITSAA
CCCCCCHHHHHHHCH
38.5119413330
1662 (in isoform 4)Phosphorylation-21.4328102081
1665O-linked_GlycosylationLPFKSIITSAAPLIS
CCHHHHHHHCHHHHC
15.6128411811
1665PhosphorylationLPFKSIITSAAPLIS
CCHHHHHHHCHHHHC
15.6127732954
1666O-linked_GlycosylationPFKSIITSAAPLISS
CHHHHHHHCHHHHCC
16.4228411811
1666PhosphorylationPFKSIITSAAPLISS
CHHHHHHHCHHHHCC
16.4230576142
1672PhosphorylationTSAAPLISSPLKSVV
HHCHHHHCCCHHHCC
33.3227732954
1673PhosphorylationSAAPLISSPLKSVVS
HCHHHHCCCHHHCCC
27.5327732954
1680PhosphorylationSPLKSVVSPVKSAVD
CCHHHCCCCCHHHHH
23.0930576142
1684O-linked_GlycosylationSVVSPVKSAVDVISS
HCCCCCHHHHHHHHH
33.4928411811
1684PhosphorylationSVVSPVKSAVDVISS
HCCCCCHHHHHHHHH
33.4946163413
1690O-linked_GlycosylationKSAVDVISSAKITMA
HHHHHHHHHCCEEHH
24.8828411811
1690PhosphorylationKSAVDVISSAKITMA
HHHHHHHHHCCEEHH
24.8823403867
1691PhosphorylationSAVDVISSAKITMAS
HHHHHHHHCCEEHHH
23.5846163421
1695O-linked_GlycosylationVISSAKITMASSLSS
HHHHCCEEHHHCCCC
13.1328411811
1695PhosphorylationVISSAKITMASSLSS
HHHHCCEEHHHCCCC
13.1346163481
1698O-linked_GlycosylationSAKITMASSLSSPVK
HCCEEHHHCCCCCCC
22.4628411811
1698PhosphorylationSAKITMASSLSSPVK
HCCEEHHHCCCCCCC
22.4646163425
1699O-linked_GlycosylationAKITMASSLSSPVKQ
CCEEHHHCCCCCCCC
23.8028411811
1701PhosphorylationITMASSLSSPVKQMP
EEHHHCCCCCCCCCC
34.2527732954
1702PhosphorylationTMASSLSSPVKQMPG
EHHHCCCCCCCCCCC
38.7223403867
1719PhosphorylationEVALVNGSISPLKYP
EEEEECCCCCCCCCC
18.0622210691
1721PhosphorylationALVNGSISPLKYPSS
EEECCCCCCCCCCCC
26.3622210691
1740O-linked_GlycosylationNGCKATATLQEKISS
CCCCCHHHHHHHHHH
25.3128411811
1746O-linked_GlycosylationATLQEKISSATNSVS
HHHHHHHHHCCCCHH
25.6228411811
1749O-linked_GlycosylationQEKISSATNSVSSVV
HHHHHHCCCCHHHHH
29.9428411811
1751O-linked_GlycosylationKISSATNSVSSVVSA
HHHHCCCCHHHHHHH
21.0128411811
1753O-linked_GlycosylationSSATNSVSSVVSAAT
HHCCCCHHHHHHHHH
19.7528411811
1757O-linked_GlycosylationNSVSSVVSAATDTVE
CCHHHHHHHHHHCHH
15.2728411811
1768O-linked_GlycosylationDTVEKVFSTTTAMPF
HCHHHHHCCCCCCCC
28.0328411811
1769O-linked_GlycosylationTVEKVFSTTTAMPFS
CHHHHHCCCCCCCCC
19.3928411811
1770O-linked_GlycosylationVEKVFSTTTAMPFSP
HHHHHCCCCCCCCCC
16.0328411811
1771O-linked_GlycosylationEKVFSTTTAMPFSPL
HHHHCCCCCCCCCCH
22.5028411811
1783O-linked_GlycosylationSPLRSYVSAAPSAFQ
CCHHHHHHHCCHHHH
15.5228411811
1791PhosphorylationAAPSAFQSLRTPSAS
HCCHHHHHCCCCCHH
17.2324719451
1794PhosphorylationSAFQSLRTPSASALY
HHHHHCCCCCHHHHH
27.2124043423
1796PhosphorylationFQSLRTPSASALYTS
HHHCCCCCHHHHHHH
33.9524043423
1798PhosphorylationSLRTPSASALYTSLG
HCCCCCHHHHHHHCC
24.1224043423
1801PhosphorylationTPSASALYTSLGSSI
CCCHHHHHHHCCCCC
8.2624043423
1802PhosphorylationPSASALYTSLGSSIS
CCHHHHHHHCCCCCC
20.5125332170
1803PhosphorylationSASALYTSLGSSISA
CHHHHHHHCCCCCCC
19.7124043423
1806PhosphorylationALYTSLGSSISATTS
HHHHHCCCCCCCCCC
29.7724043423
1807PhosphorylationLYTSLGSSISATTSS
HHHHCCCCCCCCCCC
20.8224043423
1809PhosphorylationTSLGSSISATTSSVT
HHCCCCCCCCCCCCC
22.8524043423
1811PhosphorylationLGSSISATTSSVTSS
CCCCCCCCCCCCCCC
22.0324043423
1812PhosphorylationGSSISATTSSVTSSI
CCCCCCCCCCCCCCE
20.7924043423
1813PhosphorylationSSISATTSSVTSSII
CCCCCCCCCCCCCEE
20.6124043423
1814PhosphorylationSISATTSSVTSSIIT
CCCCCCCCCCCCEEE
27.5924043423
1816PhosphorylationSATTSSVTSSIITVP
CCCCCCCCCCEEEEE
20.7824043423
1817PhosphorylationATTSSVTSSIITVPV
CCCCCCCCCEEEEEE
19.8624043423
1818PhosphorylationTTSSVTSSIITVPVY
CCCCCCCCEEEEEEE
14.5124043423
1821PhosphorylationSVTSSIITVPVYSVV
CCCCCEEEEEEEEEE
19.6524043423
1825PhosphorylationSIITVPVYSVVNVLP
CEEEEEEEEEEECCC
6.9524043423
1826PhosphorylationIITVPVYSVVNVLPE
EEEEEEEEEEECCCH
21.5924043423
1838AcetylationLPEPALKKLPDSNSF
CCHHHHHCCCCCCCC
67.1319816181
1844PhosphorylationKKLPDSNSFTKSAAA
HCCCCCCCCCHHHHH
37.9424719451
1847AcetylationPDSNSFTKSAAALLS
CCCCCCCHHHHHHHH
35.7719816187
1854PhosphorylationKSAAALLSPIKTLTT
HHHHHHHHCCEECCC
25.9824245541
1857AcetylationAALLSPIKTLTTETH
HHHHHCCEECCCCCC
40.6519816193
1860PhosphorylationLSPIKTLTTETHPQP
HHCCEECCCCCCCCC
28.0250565181
1872PhosphorylationPQPHFSRTSSPVKSS
CCCCCCCCCCCCCHH
32.1523312004
1873PhosphorylationQPHFSRTSSPVKSSL
CCCCCCCCCCCCHHH
31.3823312004
1874PhosphorylationPHFSRTSSPVKSSLF
CCCCCCCCCCCHHHE
32.8524719451
1878PhosphorylationRTSSPVKSSLFLAPS
CCCCCCCHHHEECCC
32.2923312004
1879PhosphorylationTSSPVKSSLFLAPSA
CCCCCCHHHEECCCH
19.8823312004
1890O-linked_GlycosylationAPSALKLSTPSSLSS
CCCHHHCCCCCCCCC
36.3628411811
1890PhosphorylationAPSALKLSTPSSLSS
CCCHHHCCCCCCCCC
36.3627732954
1891PhosphorylationPSALKLSTPSSLSSS
CCHHHCCCCCCCCCC
37.3127732954
1893PhosphorylationALKLSTPSSLSSSQE
HHHCCCCCCCCCCHH
43.9627732954
1894O-linked_GlycosylationLKLSTPSSLSSSQEI
HHCCCCCCCCCCHHH
33.2128411811
1894PhosphorylationLKLSTPSSLSSSQEI
HHCCCCCCCCCCHHH
33.2127732954
1896PhosphorylationLSTPSSLSSSQEILK
CCCCCCCCCCHHHHH
29.8627732954
1897PhosphorylationSTPSSLSSSQEILKD
CCCCCCCCCHHHHHH
41.1427732954
1898PhosphorylationTPSSLSSSQEILKDV
CCCCCCCCHHHHHHH
28.5827732954
1971UbiquitinationKDVCVDNKGSPKSPK
CCCCCCCCCCCCCCC
57.19-
1973PhosphorylationVCVDNKGSPKSPKSD
CCCCCCCCCCCCCCC
30.6627732954
1975UbiquitinationVDNKGSPKSPKSDKG
CCCCCCCCCCCCCCC
79.62-
1976PhosphorylationDNKGSPKSPKSDKGH
CCCCCCCCCCCCCCC
40.7327732954
1979PhosphorylationGSPKSPKSDKGHSPE
CCCCCCCCCCCCCCC
48.1918510355
1984PhosphorylationPKSDKGHSPEDDWIE
CCCCCCCCCCCCCCC
38.3627732954
2007PhosphorylationARQQAAASQSPSLPE
HHHHHHHHCCCCCCH
26.8524719451
2009PhosphorylationQQAAASQSPSLPERV
HHHHHHCCCCCCHHH
17.6027732954
2011PhosphorylationAAASQSPSLPERVQV
HHHHCCCCCCHHHHH
62.9027732954
2058AcetylationYKFEDAKKDGEERQK
EEHHHHHHCHHHHHH
73.0930585971
2065AcetylationKDGEERQKRVLKPAI
HCHHHHHHHHHHHHH
51.1730585975
2085PhosphorylationKLKMPPASMRTSTSE
CCCCCCHHHCCCCCH
17.9946163429
2089PhosphorylationPPASMRTSTSEKELC
CCHHHCCCCCHHHHH
21.4129759185
2091PhosphorylationASMRTSTSEKELCKM
HHHCCCCCHHHHHHH
46.5729759185
2107PhosphorylationDSFFGTDTILESPDD
HHHCCCCCCCCCCCC
27.5727732954
2111PhosphorylationGTDTILESPDDFSQH
CCCCCCCCCCCHHHC
30.1327732954
2116PhosphorylationLESPDDFSQHDQDKS
CCCCCCHHHCCCCCC
33.3327732954
2123PhosphorylationSQHDQDKSPLSDSGF
HHCCCCCCCCCCCCC
39.09-
2126PhosphorylationDQDKSPLSDSGFETR
CCCCCCCCCCCCCCC
32.8727732954
2128PhosphorylationDKSPLSDSGFETRSE
CCCCCCCCCCCCCCC
41.8427732954
2146PhosphorylationSAPQSAESTGPKPLF
CCCCCHHHCCCCCCC
38.0821892823
2147PhosphorylationAPQSAESTGPKPLFH
CCCCHHHCCCCCCCC
49.3521892821
2167O-linked_GlycosylationPVITETRTEVVHVIR
CEECCCCCEEEEEHH
40.3228411811
2193PhosphorylationTQPEEPVSPKPSPTF
CCCCCCCCCCCCCCC
37.6126091039
2235PhosphorylationDDHNRVLSKGMRVKE
CHHHHHHHCCCCCCC
25.0628387310
2244PhosphorylationGMRVKEETHITTTTR
CCCCCCEEEEEEEEE
21.4825367160
2248PhosphorylationKEETHITTTTRMVYH
CCEEEEEEEEEEEEE
26.1050565189
2250PhosphorylationETHITTTTRMVYHSP
EEEEEEEEEEEEECC
18.0650565209
2254PhosphorylationTTTTRMVYHSPPGGE
EEEEEEEEECCCCCC
6.2925367160
2256PhosphorylationTTRMVYHSPPGGEGA
EEEEEEECCCCCCCH
18.3327732954
2272PhosphorylationERIEETMSVHDIMKA
HHHHHHHCHHHHHHH
24.5846163437
2298PhosphorylationAGLFEHKSAVSPDVH
HHHHCCHHCCCHHHH
35.4928985074
2301PhosphorylationFEHKSAVSPDVHKSA
HCCHHCCCHHHHHHH
18.3328985074
2312PhosphorylationHKSAAETSAQHAEKD
HHHHHHHHHHHHHHC
19.8928985074
2414PhosphorylationLESSRVNTPVSQEED
HHHCCCCCCCCCCCC
23.3927732954
2417PhosphorylationSRVNTPVSQEEDSRP
CCCCCCCCCCCCCCC
32.8327732954
2422PhosphorylationPVSQEEDSRPSSAQL
CCCCCCCCCCCCCCC
49.7427732954
2425PhosphorylationQEEDSRPSSAQLISD
CCCCCCCCCCCCCCC
36.8821406692
2426PhosphorylationEEDSRPSSAQLISDD
CCCCCCCCCCCCCCC
23.7921406692
2431PhosphorylationPSSAQLISDDSYKTL
CCCCCCCCCCHHHHH
43.9121406692
2434PhosphorylationAQLISDDSYKTLKLL
CCCCCCCHHHHHHHH
33.2521406692
2435PhosphorylationQLISDDSYKTLKLLS
CCCCCCHHHHHHHHH
18.2621406692
2442PhosphorylationYKTLKLLSQHSIEYH
HHHHHHHHHHCCEEC
35.9627732954
2445PhosphorylationLKLLSQHSIEYHDDE
HHHHHHHCCEECHHH
14.9627732954
2470PhosphorylationFAEKMLLSEKLDVSH
HHHHHHHHCCCCCCC
28.8224719451
2476PhosphorylationLSEKLDVSHSDTEES
HHCCCCCCCCCCCCH
19.5524719451
2478PhosphorylationEKLDVSHSDTEESVT
CCCCCCCCCCCCHHC
38.4325849741
2480PhosphorylationLDVSHSDTEESVTDH
CCCCCCCCCCHHCCC
44.6727732954
2483PhosphorylationSHSDTEESVTDHAGP
CCCCCCCHHCCCCCC
24.8827732954
2485PhosphorylationSDTEESVTDHAGPPS
CCCCCHHCCCCCCCH
31.2027732954
2492PhosphorylationTDHAGPPSSELQGSD
CCCCCCCHHHHCCCC
39.3127732954
2493PhosphorylationDHAGPPSSELQGSDK
CCCCCCHHHHCCCCH
48.3727732954
2508O-linked_GlycosylationRSREKIATAPKKEIL
HHHHHHCCCCHHHHH
47.1428411811
2508PhosphorylationRSREKIATAPKKEIL
HHHHHHCCCCHHHHH
47.1424706070
2523PhosphorylationSKIYKDVSENGVGKV
HHHHHCHHHCCCCCC
35.1650565185
2540PhosphorylationDEHFDKVTVLHYSGN
CCCCCEEEEEEEECC
24.0824719451
2544PhosphorylationDKVTVLHYSGNVSSP
CEEEEEEEECCCCCC
17.7011398009
2549PhosphorylationLHYSGNVSSPKHAMW
EEEECCCCCCCCEEE
44.9428348404
2550PhosphorylationHYSGNVSSPKHAMWM
EEECCCCCCCCEEEE
33.4128348404
2592PhosphorylationEEKLTEVSQFFRDKT
HHHHHHHHHHHHHHH
18.2982900641
2599PhosphorylationSQFFRDKTEKLNDEL
HHHHHHHHHHHHHHH
42.5121406692
2608PhosphorylationKLNDELQSPEKKARP
HHHHHHCCCCCCCCC
47.8833651767
2621PhosphorylationRPKNGKEYSSQSPTS
CCCCCCCCCCCCCCC
19.6724043423
2622PhosphorylationPKNGKEYSSQSPTSS
CCCCCCCCCCCCCCC
24.0027732954
2623PhosphorylationKNGKEYSSQSPTSSS
CCCCCCCCCCCCCCC
33.5027732954
2625PhosphorylationGKEYSSQSPTSSSPE
CCCCCCCCCCCCCHH
31.9027732954
2627PhosphorylationEYSSQSPTSSSPEKV
CCCCCCCCCCCHHHH
46.6325307156
2628PhosphorylationYSSQSPTSSSPEKVL
CCCCCCCCCCHHHHH
32.0027732954
2629PhosphorylationSSQSPTSSSPEKVLL
CCCCCCCCCHHHHHH
53.0130177828
2630PhosphorylationSQSPTSSSPEKVLLT
CCCCCCCCHHHHHHH
36.5224043423
2668PhosphorylationKAEEKAPSLPSSPEK
HHHHCCCCCCCCHHH
58.7427732954
2671PhosphorylationEKAPSLPSSPEKMVL
HCCCCCCCCHHHEEE
64.9127732954
2672PhosphorylationKAPSLPSSPEKMVLS
CCCCCCCCHHHEEEC
34.837248853
2679PhosphorylationSPEKMVLSQQTEDSK
CHHHEEECEECCCCC
14.6130631047
2687PhosphorylationQQTEDSKSTVEAKGS
EECCCCCCCCEEECC
41.4530631047
2694PhosphorylationSTVEAKGSISQSKAP
CCCEEECCCCCCCCC
20.5446163441
2696PhosphorylationVEAKGSISQSKAPDG
CEEECCCCCCCCCCC
30.0546163445
2698PhosphorylationAKGSISQSKAPDGPQ
EECCCCCCCCCCCCC
24.8046163449
2716PhosphorylationQLKQSKLSSIRLKFE
CCCHHHHHHCEEEEC
27.7030301811
2717PhosphorylationLKQSKLSSIRLKFEQ
CCHHHHHHCEEEECC
23.3625954137
2739UbiquitinationDMSQEDRKSDGQSRI
CCCHHHHHCCCCCCC
66.28-
2749UbiquitinationGQSRIPVKKIQESKL
CCCCCCHHHHHHCCC
38.51-
2779O-linked_GlycosylationDLPDESVSVQKDFMV
CCCCCCCCCCCCEEE
28.2728411811
2858PhosphorylationVFRTWESSGATNNKS
HHHHHHCCCCCCCHH
22.4150565177
2871PhosphorylationKSQKEKLSHVLVHDV
HHHHHHHHHHHHHHH
23.7124732914
2909PhosphorylationERERKLLTNGSLSEI
HHHHHHHHCCCHHHH
48.2220068231
2912PhosphorylationRKLLTNGSLSEIKEM
HHHHHCCCHHHHHHC
30.6920068231
2914PhosphorylationLLTNGSLSEIKEMTV
HHHCCCHHHHHHCCC
38.6820068231
2923PhosphorylationIKEMTVKSPSKKVLY
HHHCCCCCCCCCEEE
30.0328060719
2925PhosphorylationEMTVKSPSKKVLYRE
HCCCCCCCCCEEEEE
52.8028060719
2991PhosphorylationAFPKHELSQKLSQSS
CCCHHHHHHHHHHHC
23.4522257651
2997PhosphorylationLSQKLSQSSMSKETV
HHHHHHHHCCCHHHH
25.3222257657
3000PhosphorylationKLSQSSMSKETVETQ
HHHHHCCCHHHHHHH
29.3222257663
3048PhosphorylationTETSPTKSPDSLEFS
CCCCCCCCCCCCCCC
36.1027732954
3051PhosphorylationSPTKSPDSLEFSPGK
CCCCCCCCCCCCCCC
32.9327732954
3055PhosphorylationSPDSLEFSPGKESPS
CCCCCCCCCCCCCCC
24.3027732954
3060PhosphorylationEFSPGKESPSSDVFD
CCCCCCCCCCCCCCC
33.3027732954
3062PhosphorylationSPGKESPSSDVFDHS
CCCCCCCCCCCCCCC
48.7427732954
3063PhosphorylationPGKESPSSDVFDHSP
CCCCCCCCCCCCCCC
40.9727732954
3069PhosphorylationSSDVFDHSPIDGLEK
CCCCCCCCCCCHHHH
25.9527732954
3083PhosphorylationKLAPLAQTEGGKEIK
HHHCHHHCCCCCEEC
30.8722199227
3091PhosphorylationEGGKEIKTLPVYVSF
CCCCEECCEEEEEEE
41.7950565205
3095PhosphorylationEIKTLPVYVSFVQVG
EECCEEEEEEEEECC
6.6169211725
3133PhosphorylationQETRGTFYTTRQQKQ
HHHCCCCEECCCCCC
13.677601361
3134PhosphorylationETRGTFYTTRQQKQP
HHCCCCEECCCCCCC
16.0023403867
3143PhosphorylationRQQKQPPSPQGSPED
CCCCCCCCCCCCCCC
36.2224076635
3147PhosphorylationQPPSPQGSPEDDTLE
CCCCCCCCCCCCCCH
21.6224043423
3152PhosphorylationQGSPEDDTLEQVSFL
CCCCCCCCCHHHCCC
44.5124076635
3157PhosphorylationDDTLEQVSFLDSSGK
CCCCHHHCCCCCCCC
21.5624043423
3161PhosphorylationEQVSFLDSSGKSPLT
HHHCCCCCCCCCCCC
43.0424043423
3162PhosphorylationQVSFLDSSGKSPLTP
HHCCCCCCCCCCCCC
50.3222250607
3168PhosphorylationSSGKSPLTPETPSSE
CCCCCCCCCCCCCCC
23.5922250613
3174PhosphorylationLTPETPSSEEVSYEF
CCCCCCCCCCEEEEE
38.6925954137
3179PhosphorylationPSSEEVSYEFTSKTP
CCCCCEEEEEECCCC
21.9025954137
3185PhosphorylationSYEFTSKTPDSLIAY
EEEEECCCCCCEEEE
31.9068707615
3188PhosphorylationFTSKTPDSLIAYIPG
EECCCCCCEEEECCC
23.9168707619
3198PhosphorylationAYIPGKPSPIPEVSE
EECCCCCCCCCCCCC
38.6627732954
3204PhosphorylationPSPIPEVSEESEEEE
CCCCCCCCCCCHHHH
33.7027732954
3207PhosphorylationIPEVSEESEEEEQAK
CCCCCCCCHHHHHHH
46.3827732954
3215PhosphorylationEEEEQAKSTSLKQTT
HHHHHHHCCCCCCCC
26.6768707623
3221PhosphorylationKSTSLKQTTVEETAV
HCCCCCCCCHHHHHH
31.0846163489
3222PhosphorylationSTSLKQTTVEETAVE
CCCCCCCCHHHHHHH
24.3521712546
3226PhosphorylationKQTTVEETAVEREMP
CCCCHHHHHHHHCCC
23.6163772351
3293PhosphorylationLQDEHDKYQLAEPVI
CCCCCCHHCCCCCEE
18.1518083107
3306PhosphorylationVIRVQPPSPVPPGAD
EEEECCCCCCCCCCC
45.2527732954
3315PhosphorylationVPPGADVSDSSDDES
CCCCCCCCCCCCCCC
32.1127732954
3317PhosphorylationPGADVSDSSDDESIY
CCCCCCCCCCCCCCC
28.3227732954
3318PhosphorylationGADVSDSSDDESIYQ
CCCCCCCCCCCCCCC
54.8127732954
3322PhosphorylationSDSSDDESIYQPVPV
CCCCCCCCCCCCCCC
33.3227732954
3324PhosphorylationSSDDESIYQPVPVKK
CCCCCCCCCCCCCCE
18.9536751557
3458PhosphorylationILKPADRSFSQSKLE
CCCCCCCCCCHHHEE
29.7823403867
3460PhosphorylationKPADRSFSQSKLEVI
CCCCCCCCHHHEEEH
34.4923403867
3462PhosphorylationADRSFSQSKLEVIEE
CCCCCCHHHEEEHHH
37.7027251275
3472AcetylationEVIEEEGKVGPDEDK
EEHHHCCCCCCCCCC
47.5020167786
3513PhosphorylationEGRHPDRSVFPDTYF
CCCCCCCCCCCCCCC
35.1750565197
3575PhosphorylationGLAVEDRSPATTPDT
CEEECCCCCCCCCCC
31.0727732954
3578PhosphorylationVEDRSPATTPDTTPA
ECCCCCCCCCCCCCC
42.0927732954
3620PhosphorylationRSGAIDMSKRDFVEE
CCCCCCCCHHHHHHH
22.3150565173
3666PhosphorylationQPQSGDTTVETNLER
CCCCCCCCCCCCEEC
22.5330624053
3709PhosphorylationLEKSAAATNTSKVDP
HHHHHCCCCCCCCCH
34.0130559295
3711PhosphorylationKSAAATNTSKVDPKL
HHHCCCCCCCCCHHH
26.1030559297
3712PhosphorylationSAAATNTSKVDPKLR
HHCCCCCCCCCHHHC
32.5230559291
3727PhosphorylationTPIKMGISASTMTMK
CCEECEECCCCCCCC
15.5022210691
3742PhosphorylationKEGPGEITDKIEAVM
CCCCCCCHHHHHHHH
27.2622985185
3764PhosphorylationNETITMISNTANSQM
CCEEEEEECCCCCCC
19.8022210691
3862AcetylationELIGIRQKSKLPIKA
HHHCCCCCCCCCCCC
39.4430585961
3864AcetylationIGIRQKSKLPIKATS
HCCCCCCCCCCCCCC
66.3819828969
3868AcetylationQKSKLPIKATSPKDT
CCCCCCCCCCCCCCC
43.6119828975
3870PhosphorylationSKLPIKATSPKDTFP
CCCCCCCCCCCCCCC
40.3330576142
3873AcetylationPIKATSPKDTFPPNH
CCCCCCCCCCCCCCC
69.997293789
3875PhosphorylationKATSPKDTFPPNHMS
CCCCCCCCCCCCCCC
44.1430631047
3884PhosphorylationPPNHMSNTKASKMKQ
CCCCCCCCCHHHHHH
22.2330576142
3887PhosphorylationHMSNTKASKMKQVSQ
CCCCCCHHHHHHCCH
34.5346163461
3888AcetylationMSNTKASKMKQVSQS
CCCCCHHHHHHCCHH
55.7819828981
3948PhosphorylationGKAKQLPSKLPVKVR
CCCCCCCCCCCCEEE
56.2524719451
3956PhosphorylationKLPVKVRSTCVTTTT
CCCCEEECEEEEEEE
29.1922468782
3957PhosphorylationLPVKVRSTCVTTTTT
CCCEEECEEEEEEEC
10.6324043423
3960PhosphorylationKVRSTCVTTTTTTAT
EEECEEEEEEECEEE
22.1424043423
3961PhosphorylationVRSTCVTTTTTTATT
EECEEEEEEECEEEE
11.1824043423
3962PhosphorylationRSTCVTTTTTTATTT
ECEEEEEEECEEEEE
16.8722468782
3963PhosphorylationSTCVTTTTTTATTTT
CEEEEEEECEEEEEE
21.7624043423
3964PhosphorylationTCVTTTTTTATTTTT
EEEEEEECEEEEEEE
16.6124043423
3965PhosphorylationCVTTTTTTATTTTTT
EEEEEECEEEEEEEE
21.6624043423
3967PhosphorylationTTTTTTATTTTTTTT
EEEECEEEEEEEEEE
23.6824043423
3968PhosphorylationTTTTTATTTTTTTTT
EEECEEEEEEEEEEE
21.4924043423
3969PhosphorylationTTTTATTTTTTTTTT
EECEEEEEEEEEEEE
20.1450565193
3970PhosphorylationTTTATTTTTTTTTTT
ECEEEEEEEEEEEEE
21.7650565213
3971PhosphorylationTTATTTTTTTTTTTT
CEEEEEEEEEEEEEE
21.7622468782
3972PhosphorylationTATTTTTTTTTTTTS
EEEEEEEEEEEEEEE
21.7624043423
3973PhosphorylationATTTTTTTTTTTTSC
EEEEEEEEEEEEEEE
21.7624043423
3974PhosphorylationTTTTTTTTTTTTSCT
EEEEEEEEEEEEEEE
21.7624043423
3975PhosphorylationTTTTTTTTTTTSCTV
EEEEEEEEEEEEEEE
21.7624043423
3976PhosphorylationTTTTTTTTTTSCTVK
EEEEEEEEEEEEEEE
26.4524043423
3977PhosphorylationTTTTTTTTTSCTVKV
EEEEEEEEEEEEEEE
18.0224043423
3978PhosphorylationTTTTTTTTSCTVKVR
EEEEEEEEEEEEEEC
21.5124043423
3979PhosphorylationTTTTTTTSCTVKVRK
EEEEEEEEEEEEECH
13.0022468782
3981PhosphorylationTTTTTSCTVKVRKSQ
EEEEEEEEEEECHHH
24.1150565225
4004PhosphorylationIEYFKGISGETLKLV
HHHHCCCCHHHHHHH
38.9646163465
4007PhosphorylationFKGISGETLKLVDRL
HCCCCHHHHHHHHHC
32.4946163497
4023PhosphorylationEEEKKMQSELSDEEE
HHHHHHHHHCCHHHH
36.6930576142
4026PhosphorylationKKMQSELSDEEESTS
HHHHHHCCHHHHHHC
38.6430576142
4031PhosphorylationELSDEEESTSRNTSL
HCCHHHHHHCCCCCC
34.6629978859
4032PhosphorylationLSDEEESTSRNTSLS
CCHHHHHHCCCCCCC
34.6829978859
4033PhosphorylationSDEEESTSRNTSLSE
CHHHHHHCCCCCCCC
32.5829978859
4041PhosphorylationRNTSLSETSRGGQPS
CCCCCCCCCCCCCCC
21.9830576142
4048PhosphorylationTSRGGQPSVTTKSAR
CCCCCCCCCCCCCCC
24.9820068231
4050PhosphorylationRGGQPSVTTKSARDK
CCCCCCCCCCCCCCC
32.6120068231
4051PhosphorylationGGQPSVTTKSARDKK
CCCCCCCCCCCCCCC
22.3520068231
4053PhosphorylationQPSVTTKSARDKKTE
CCCCCCCCCCCCCCC
26.8320068231
4078PhosphorylationAGSEKRSSRRTGPQS
CCCCCCCCCCCCCCC
29.7946163469
4081PhosphorylationEKRSSRRTGPQSPCE
CCCCCCCCCCCCCCC
52.7046163505
4115PhosphorylationLARELNFSVDEINQI
HHHHCCCCHHHHHHE
27.8223312004
4129PhosphorylationIRVENPNSLISQSFM
EECCCCCCHHHHHHH
28.4723403867
4134PhosphorylationPNSLISQSFMLLKKW
CCCHHHHHHHHHHHH
13.0623403867
4143PhosphorylationMLLKKWVTRDGKNAT
HHHHHHHHCCCCCCC
23.1746163509
4177PhosphorylationLEGPIFDYGNISGTR
EECCCCCCCCCCCCC
11.00119625
4181PhosphorylationIFDYGNISGTRSFAD
CCCCCCCCCCCCCCC
37.8029496963
4183PhosphorylationDYGNISGTRSFADEN
CCCCCCCCCCCCCCC
19.1527732954
4211PhosphorylationTSSGNLESCAQARRV
CCCCCHHHHHHHHHH
20.23-
4219PhosphorylationCAQARRVTGGLLDRL
HHHHHHHHHCHHHHC
24.5823312004
4229PhosphorylationLLDRLDDSPDQCRDS
HHHHCCCCHHHHHHH
30.0025159151
4236PhosphorylationSPDQCRDSITSYLKG
CHHHHHHHHHHHHCC
14.3928857561
4238PhosphorylationDQCRDSITSYLKGEA
HHHHHHHHHHHCCCC
18.4428102081
4239PhosphorylationQCRDSITSYLKGEAG
HHHHHHHHHHCCCCC
27.1428102081
4240PhosphorylationCRDSITSYLKGEAGK
HHHHHHHHHCCCCCC
12.0929978859
4253PhosphorylationGKFEANGSHTEITPE
CCCEECCCCCEECCC
27.3525159151
4255PhosphorylationFEANGSHTEITPEAK
CEECCCCCEECCCCC
30.6826657352
4258PhosphorylationNGSHTEITPEAKTKS
CCCCCEECCCCCCCC
14.6225849741
4266PhosphorylationPEAKTKSYFPESQND
CCCCCCCCCCCCCCC
25.397947913
4270PhosphorylationTKSYFPESQNDVGKQ
CCCCCCCCCCCCCCC
34.2228348404
4278PhosphorylationQNDVGKQSTKETLKP
CCCCCCCCCHHHHCC
44.9528857561
4279PhosphorylationNDVGKQSTKETLKPK
CCCCCCCCHHHHCCC
30.3328348404
4290PhosphorylationLKPKIHGSGHVEEPA
HCCCCCCCCCCCCCC
16.1525159151
4298PhosphorylationGHVEEPASPLAAYQK
CCCCCCCCHHHHHHH
31.0325159151
4303PhosphorylationPASPLAAYQKSLEET
CCCHHHHHHHHHHHH
15.7424972180
4306PhosphorylationPLAAYQKSLEETSKL
HHHHHHHHHHHHHHH
26.0328857561
4318PhosphorylationSKLIIEETKPCVPVS
HHHHHHCCCCCEECC
27.7429759185
4325PhosphorylationTKPCVPVSMKKMSRT
CCCCEECCHHCCCCC
20.8625159151
4327AcetylationPCVPVSMKKMSRTSP
CCEECCHHCCCCCCC
37.5112429917
4328AcetylationCVPVSMKKMSRTSPA
CEECCHHCCCCCCCC
33.2012431437
4330PhosphorylationPVSMKKMSRTSPADG
ECCHHCCCCCCCCCC
41.09113315053
4332PhosphorylationSMKKMSRTSPADGKP
CHHCCCCCCCCCCCC
31.5828985074
4333PhosphorylationMKKMSRTSPADGKPR
HHCCCCCCCCCCCCC
19.5823927012
4338UbiquitinationRTSPADGKPRLSLHE
CCCCCCCCCCCEEEC
27.7517370265
4342PhosphorylationADGKPRLSLHEEEGS
CCCCCCCEEECCCCC
29.0329255136
4349PhosphorylationSLHEEEGSSGSEQKQ
EEECCCCCCCCCCCC
34.5023927012
4350PhosphorylationLHEEEGSSGSEQKQG
EECCCCCCCCCCCCC
58.1430278072
4352PhosphorylationEEEGSSGSEQKQGEG
CCCCCCCCCCCCCCC
38.5125850435

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ANK3_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ANK3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ANK3_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KCNC1_HUMANKCNC1physical
12805291
SPTN4_HUMANSPTBN4physical
11807096
TIAM1_HUMANTIAM1physical
10893266

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
Note=Genetic variations in ANK3 may be associated with autism spectrum disorders susceptibility.
615493
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ANK3_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1459, AND MASSSPECTROMETRY.
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry.";
Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4298, AND MASSSPECTROMETRY.
"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer.";
Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.;
Cell 131:1190-1203(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-533, AND MASSSPECTROMETRY.
Ubiquitylation
ReferencePubMed
"Tryptic digestion of ubiquitin standards reveals an improved strategyfor identifying ubiquitinated proteins by mass spectrometry.";
Denis N.J., Vasilescu J., Lambert J.-P., Smith J.C., Figeys D.;
Proteomics 7:868-874(2007).
Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-4338, AND MASSSPECTROMETRY.

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