| UniProt ID | MINY3_HUMAN | |
|---|---|---|
| UniProt AC | Q9H8M7 | |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase MINDY-3 | |
| Gene Name | MINDY3 {ECO:0000312|HGNC:HGNC:23578} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 445 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.. | |
| Protein Sequence | MSELTKELMELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCSEEEQKELLCHTLCDILESACCDHSGSYCLVSWLRGKTTEETASISGSPAESSCQVEHSSALAVEELGFERFHALIQKRSFRSLPELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNEIEDASEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMKLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIPDSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 16 | Ubiquitination | MELVWGTKSSPGLSD HHHHHCCCCCCCCCC | 21963094 | ||
| 17 | Phosphorylation | ELVWGTKSSPGLSDT HHHHCCCCCCCCCCC | 25159151 | ||
| 18 | Phosphorylation | LVWGTKSSPGLSDTI HHHCCCCCCCCCCCE | 25159151 | ||
| 63 | Ubiquitination | PVQAFLLKKLLFSSE HHHHHHHHHHHHCCC | 22817900 | ||
| 64 | Ubiquitination | VQAFLLKKLLFSSEK HHHHHHHHHHHCCCC | 21906983 | ||
| 64 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 64 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 71 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 71 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 71 | Ubiquitination | KLLFSSEKSSWRDCS HHHHCCCCCCCCCCC | 23000965 | ||
| 94 | Ubiquitination | CHTLCDILESACCDH HHHHHHHHHHHHCCC | 21890473 | ||
| 114 (in isoform 2) | Ubiquitination | - | - | ||
| 114 | Ubiquitination | LVSWLRGKTTEETAS EEEECCCCCCCCEEC | 29967540 | ||
| 119 | Phosphorylation | RGKTTEETASISGSP CCCCCCCEECCCCCC | 27080861 | ||
| 120 | Ubiquitination | GKTTEETASISGSPA CCCCCCEECCCCCCC | 21890473 | ||
| 123 | Phosphorylation | TEETASISGSPAESS CCCEECCCCCCCCCC | 27080861 | ||
| 125 | Phosphorylation | ETASISGSPAESSCQ CEECCCCCCCCCCCE | 25159151 | ||
| 155 | Ubiquitination | RFHALIQKRSFRSLP HHHHHHHHCCCCCCH | 29967540 | ||
| 175 | Ubiquitination | VLDQYSMWGNKFGVL HHHHHHCCCHHHHHH | 29967540 | ||
| 222 | Ubiquitination | HGSQSLINLLLTGHA CCHHHHHHHHHHCCC | 22817900 | ||
| 241 | Phosphorylation | WDGDRECSGMKLLGI CCCCCCCCCCEEEEE | - | ||
| 249 | Ubiquitination | GMKLLGIHEQAAVGF CCEEEEEHHHHHHHH | 22817900 | ||
| 267 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 267 | Ubiquitination | MEALRYCKVGSYLKS HHHHHHCCHHHHCCC | 21890473 | ||
| 270 | Phosphorylation | LRYCKVGSYLKSPKF HHHCCHHHHCCCCCC | - | ||
| 274 | Phosphorylation | KVGSYLKSPKFPIWI CHHHHCCCCCCCEEE | 24719451 | ||
| 275 | Ubiquitination | VGSYLKSPKFPIWIV HHHHCCCCCCCEEEE | 22817900 | ||
| 296 | Sulfoxidation | TVFFAKDMALVAPEA EEEEECCCCHHCCCC | 21406390 | ||
| 348 | Ubiquitination | PEYINLMKNKLDPEG HHHHHHHCCCCCHHC | 29967540 | ||
| 395 | Ubiquitination | LKQSNYNEKVMYVEG CCCCCCCCCEEEEEC | 22817900 | ||
| 399 | Phosphorylation | NYNEKVMYVEGTAVV CCCCCEEEEECCEEE | 24719451 | ||
| 422 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 422 | Ubiquitination | QTDDTPIKRCLQTKW CCCCCCHHHHHHCCC | 21906983 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MINY3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MINY3_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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