CAF17_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CAF17_HUMAN
• UniProt AC: Q5T440
• Protein Name: Putative transferase CAF17, mitochondrial
• Gene Name: IBA57
• Organism: Homo sapiens (Human).
• Sequence Length: 356
• Subcellular Localization: Mitochondrion .
• Protein Description: Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway..
• Protein Sequence: MATAALLRGATPGRGGPVWRWRLRAAPRCRLAHSSCSPGGDPTAGAAWACFRLDGRTLLRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEHSEVSGFLLECDSSVQGALQKHLALYRIRRKVTVEPHPELRVWAVLPSSPEACGAASLQERAGAAAILIRDPRTARMGWRLLTQDEGPALVPGGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLESNLAFMNGVSFTKGCYIGQELTARTHHMGVIRKRLFPVRFLDPLPTSGITPGATVLTASGQTVGKFRAGQGNVGLALLWSEKIKGPLHIRASEGAQVALAASVPDWWPTVSK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Methylation	LRGATPGRGGPVWRW HCCCCCCCCCCHHHH	48.36	115480097
82	Phosphorylation	TNELPLPSPAAAGAP HCCCCCCCHHHCCCC	34.55	-
200	Phosphorylation	RMGWRLLTQDEGPAL HCCEEEEECCCCCCC	38.27	-
245	Phosphorylation	GVALPLESNLAFMNG CCEEECCCCEEEECC	44.84	26126808
254	Phosphorylation	LAFMNGVSFTKGCYI EEEECCCEECCCCCC	28.70	24719451
256	Phosphorylation	FMNGVSFTKGCYIGQ EECCCEECCCCCCCC	21.01	26126808
306	Phosphorylation	VLTASGQTVGKFRAG EEEECCCEEEEEECC	34.45	-
309	Acetylation	ASGQTVGKFRAGQGN ECCCEEEEEECCCCC	27.60	23954790
309	Malonylation	ASGQTVGKFRAGQGN ECCCEEEEEECCCCC	27.60	26320211
309	Succinylation	ASGQTVGKFRAGQGN ECCCEEEEEECCCCC	27.60	-
309	Succinylation	ASGQTVGKFRAGQGN ECCCEEEEEECCCCC	27.60	-
324	Phosphorylation	VGLALLWSEKIKGPL CEEEEEECCCCCCCE	29.05	20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CAF17_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CAF17_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CAF17_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CA123_HUMAN	C1orf123	physical	26344197

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.