dbPTM

ZN644_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZN644_HUMAN
UniProt AC	Q9H582
Protein Name	Zinc finger protein 644
Gene Name	ZNF644
Organism	Homo sapiens (Human).
Sequence Length	1327
Subcellular Localization	Nucleus.
Protein Description	May be involved in transcriptional regulation..
Protein Sequence	MRSFLQQDVNKTKSRLNVLNGLANNMDDLKINTDITGAKEELLDDNNFISDKESGVHKPKDCQTSFQKNNTLTLPEELSKDKSENALSGGQSSLFIHAGAPTVSSENFILPKGAAVNGPVSHSSLTKTSNMNKGSVSLTTGQPVDQPTTESCSTLKVAADLQLSTPQKASQHQVLFLLSDVAHAKNPTHSNKKLPTSASVGCDIQNSVGSNIKSDGTLINQVEVGEDGEDLLVKDDCVNTVTGISSGTDGFRSENDTNWDPQKEFIQFLMTNEETVDKAPPHSKIGLEKKRKRKMDVSKITRYTEDCFSDSNCVPNKSKMQEVDFLEQNEELQAVDSQKYALSKVKPESTDEDLESVDAFQHLIYNPDKCGEESSPVHTSTFLSNTLKKKCEESDSESPATFSTEEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAVVKCPMVTSDIAQRKTQKKTFMKDSVVGSSKKSATYICKMCPFTTSAKSVLKKHTEYLHSSSCVDSFGSPLGLDKRKNDILEEPVDSDSTKTLTKQQSTTFPKNSALKQDVKRTFGSTSQSSSFSKIHKRPHRIQKARKSIAQSGVNMCNQNSSPHKNVTIKSSVDQKPKYFHQAAKEKSNAKANSHYLYRHKYENYRMIKKSGESYPVHFKKEEASSLNSLHLFSSSSNSHNNFISDPHKPDAKRPESFKDHRRVAVKRVIKESKKESSVGGEDLDSYPDFLHKMTVVVLQKLNSAEKKDSYETEDESSWDNVELGDYTTQAIEDETYSDINQEHVNLFPLFKSKVEGQEPGENATLSYDQNDGFYFEYYEDTGSNNFLHEIHDPQHLETADASLSKHSSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKAIEKSETTSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRIIPRPFVAQKLASSDDFISQNVIPLEAYRNGLKTEALSVSASEEEGLNFLNEYDETKPELPSGKKNQSLTLIELLKNKRMGEERNSAISPQKIHNQTARKRFVQKCVLPLNEDSPLMYQPQKMDLTMHSALDCKQKKSRSRSGSKKKMLTLPHGADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
39	Sumoylation	NTDITGAKEELLDDN CCCCCCCHHHHCCCC	53.73	-
39	Sumoylation	NTDITGAKEELLDDN CCCCCCCHHHHCCCC	53.73	28112733
50	Phosphorylation	LDDNNFISDKESGVH CCCCCCCCCCCCCCC	38.19	22777824
54	Phosphorylation	NFISDKESGVHKPKD CCCCCCCCCCCCCCC	52.43	20873877
71	Phosphorylation	TSFQKNNTLTLPEEL CCCHHCCCCCCCHHH	30.43	28555341
73	Phosphorylation	FQKNNTLTLPEELSK CHHCCCCCCCHHHCC	37.92	19664994
74 (in isoform 1)	Phosphorylation	-	5.90	-
82	Sumoylation	PEELSKDKSENALSG CHHHCCCCCCCCCCC	64.50	28112733
83	Phosphorylation	EELSKDKSENALSGG HHHCCCCCCCCCCCC	46.33	-
104	Phosphorylation	HAGAPTVSSENFILP ECCCCCCCCCCEEEC	34.12	-
105	Phosphorylation	AGAPTVSSENFILPK CCCCCCCCCCEEECC	32.02	-
112	Sumoylation	SENFILPKGAAVNGP CCCEEECCCCCCCCC	58.71	28112733
121	Phosphorylation	AAVNGPVSHSSLTKT CCCCCCCCCCCCCCC	22.30	28555341
123	Phosphorylation	VNGPVSHSSLTKTSN CCCCCCCCCCCCCCC	21.38	25627689
124	Phosphorylation	NGPVSHSSLTKTSNM CCCCCCCCCCCCCCC	34.33	25159151
139	Phosphorylation	NKGSVSLTTGQPVDQ CCCCEEEECCCCCCC	22.75	28555341
164	Phosphorylation	VAADLQLSTPQKASQ HEEEEECCCCCCCHH	25.69	30266825
165	Phosphorylation	AADLQLSTPQKASQH EEEEECCCCCCCHHH	38.03	30266825
168	Sumoylation	LQLSTPQKASQHQVL EECCCCCCCHHHHHH	51.73	28112733
170	Phosphorylation	LSTPQKASQHQVLFL CCCCCCCHHHHHHHH	34.92	24732914
185	Sumoylation	LSDVAHAKNPTHSNK HHHHHHHCCCCCCCC	54.30	28112733
193	Sumoylation	NPTHSNKKLPTSASV CCCCCCCCCCCCCCC	65.04	28112733
196	Phosphorylation	HSNKKLPTSASVGCD CCCCCCCCCCCCCCC	47.57	28450419
197	Phosphorylation	SNKKLPTSASVGCDI CCCCCCCCCCCCCCC	19.33	28450419
199	Phosphorylation	KKLPTSASVGCDIQN CCCCCCCCCCCCCCC	20.86	28450419
213	Sumoylation	NSVGSNIKSDGTLIN CCCCCCCCCCCCEEE	46.90	28112733
253	Phosphorylation	SGTDGFRSENDTNWD CCCCCCCCCCCCCCC	38.19	25627689
263	Sumoylation	DTNWDPQKEFIQFLM CCCCCHHHHHHHHHH	61.04	28112733
284	Sumoylation	DKAPPHSKIGLEKKR CCCCCCCCCCCCHHH	37.45	28112733
294	Sumoylation	LEKKRKRKMDVSKIT CCHHHHCCCCHHHHH	42.35	28112733
298	Phosphorylation	RKRKMDVSKITRYTE HHCCCCHHHHHHHCH	17.68	-
299	Acetylation	KRKMDVSKITRYTED HCCCCHHHHHHHCHH	48.20	7681953
299	Sumoylation	KRKMDVSKITRYTED HCCCCHHHHHHHCHH	48.20	28112733
303	Phosphorylation	DVSKITRYTEDCFSD CHHHHHHHCHHHCCC	13.06	28985074
309	Phosphorylation	RYTEDCFSDSNCVPN HHCHHHCCCCCCCCC	46.60	25159151
311	Phosphorylation	TEDCFSDSNCVPNKS CHHHCCCCCCCCCHH	30.82	30576142
319	Sumoylation	NCVPNKSKMQEVDFL CCCCCHHHHCCCCHH	46.33	-
319	Sumoylation	NCVPNKSKMQEVDFL CCCCCHHHHCCCCHH	46.33	28112733
319	Ubiquitination	NCVPNKSKMQEVDFL CCCCCHHHHCCCCHH	46.33	-
339	Sumoylation	LQAVDSQKYALSKVK HHHHHHHHHHHHCCC	36.12	-
339	Sumoylation	LQAVDSQKYALSKVK HHHHHHHHHHHHCCC	36.12	28112733
344	Sumoylation	SQKYALSKVKPESTD HHHHHHHCCCCCCCC	55.94	28112733
346	Sumoylation	KYALSKVKPESTDED HHHHHCCCCCCCCCH	46.97	-
346	Sumoylation	KYALSKVKPESTDED HHHHHCCCCCCCCCH	46.97	25114211
346	Ubiquitination	KYALSKVKPESTDED HHHHHCCCCCCCCCH	46.97	-
349	Phosphorylation	LSKVKPESTDEDLES HHCCCCCCCCCHHHC	50.08	30266825
350	Phosphorylation	SKVKPESTDEDLESV HCCCCCCCCCHHHCC	41.57	30266825
356	Phosphorylation	STDEDLESVDAFQHL CCCCHHHCCHHHHHH	32.37	30266825
369	Ubiquitination	HLIYNPDKCGEESSP HHHCCCCCCCCCCCC	45.45	-
374	Phosphorylation	PDKCGEESSPVHTST CCCCCCCCCCCCHHH	35.32	23401153
375	Phosphorylation	DKCGEESSPVHTSTF CCCCCCCCCCCHHHH	33.93	25159151
379	Phosphorylation	EESSPVHTSTFLSNT CCCCCCCHHHHHHHH	29.69	27251275
380	Phosphorylation	ESSPVHTSTFLSNTL CCCCCCHHHHHHHHH	11.41	27251275
381	Phosphorylation	SSPVHTSTFLSNTLK CCCCCHHHHHHHHHH	29.74	29083192
384	Phosphorylation	VHTSTFLSNTLKKKC CCHHHHHHHHHHHHH	24.47	29083192
386	Phosphorylation	TSTFLSNTLKKKCEE HHHHHHHHHHHHHHC	36.26	29083192
388	Sumoylation	TFLSNTLKKKCEESD HHHHHHHHHHHHCCC	48.42	28112733
390	Sumoylation	LSNTLKKKCEESDSE HHHHHHHHHHCCCCC	45.34	28112733
394	Phosphorylation	LKKKCEESDSESPAT HHHHHHCCCCCCCCC	24.92	25159151
396	Phosphorylation	KKCEESDSESPATFS HHHHCCCCCCCCCCC	49.61	30576142
398	Phosphorylation	CEESDSESPATFSTE HHCCCCCCCCCCCCC	24.64	30576142
401	Phosphorylation	SDSESPATFSTEEPS CCCCCCCCCCCCCCC	22.85	30576142
403	Phosphorylation	SESPATFSTEEPSFY CCCCCCCCCCCCCCC	30.47	23090842
404	Phosphorylation	ESPATFSTEEPSFYP CCCCCCCCCCCCCCC	39.93	23090842
446	Dimethylation	FRHLNVPRPYACREC CCCCCCCCCCHHHHH	32.36	-
446	Methylation	FRHLNVPRPYACREC CCCCCCCCCCHHHHH	32.36	30763593
462	Phosphorylation	RTFRDRNSLLKHMII CCHHCHHHHHHHHHH	35.65	24719451
485	Ubiquitination	MEEIRELKELQDEGR HHHHHHHHHHHHCHH	52.18	-
485	Sumoylation	MEEIRELKELQDEGR HHHHHHHHHHHHCHH	52.18	28112733
509	Ubiquitination	VFGTNCPKTFVQHAK CCCCCCCHHHHHHHH	57.71	-
509	Sumoylation	VFGTNCPKTFVQHAK CCCCCCCHHHHHHHH	57.71	28112733
553	Ubiquitination	IAHGAVVKCPMVTSD CCCCCEEECCCCCHH	26.48	-
553	Sumoylation	IAHGAVVKCPMVTSD CCCCCEEECCCCCHH	26.48	28112733
570	Phosphorylation	QRKTQKKTFMKDSVV HHHHHCCCCCCCCCC	35.68	-
573	Acetylation	TQKKTFMKDSVVGSS HHCCCCCCCCCCCCC	42.53	7675617
573	Sumoylation	TQKKTFMKDSVVGSS HHCCCCCCCCCCCCC	42.53	28112733
579	Phosphorylation	MKDSVVGSSKKSATY CCCCCCCCCCCCCCH	27.63	20068231
580	Phosphorylation	KDSVVGSSKKSATYI CCCCCCCCCCCCCHH	37.87	20068231
589	Acetylation	KSATYICKMCPFTTS CCCCHHHHHCCCCCC	33.70	7675627
589	Sumoylation	KSATYICKMCPFTTS CCCCHHHHHCCCCCC	33.70	-
589	Sumoylation	KSATYICKMCPFTTS CCCCHHHHHCCCCCC	33.70	28112733
589	Ubiquitination	KSATYICKMCPFTTS CCCCHHHHHCCCCCC	33.70	-
598	Sumoylation	CPFTTSAKSVLKKHT CCCCCCHHHHHHHHH	40.64	28112733
599	Phosphorylation	PFTTSAKSVLKKHTE CCCCCHHHHHHHHHH	32.19	24117733
603	Ubiquitination	SAKSVLKKHTEYLHS CHHHHHHHHHHHHHC	52.15	-
603	Sumoylation	SAKSVLKKHTEYLHS CHHHHHHHHHHHHHC	52.15	28112733
616	Phosphorylation	HSSSCVDSFGSPLGL HCCCCCCCCCCCCCC	15.88	29214152
619	Phosphorylation	SCVDSFGSPLGLDKR CCCCCCCCCCCCCCC	18.23	18669648
625	Ubiquitination	GSPLGLDKRKNDILE CCCCCCCCCCCCCCC	71.02	-
627	Sumoylation	PLGLDKRKNDILEEP CCCCCCCCCCCCCCC	65.79	-
627	Sumoylation	PLGLDKRKNDILEEP CCCCCCCCCCCCCCC	65.79	28112733
627	Ubiquitination	PLGLDKRKNDILEEP CCCCCCCCCCCCCCC	65.79	-
637	Phosphorylation	ILEEPVDSDSTKTLT CCCCCCCCCCCCCCC	33.42	30266825
639	Phosphorylation	EEPVDSDSTKTLTKQ CCCCCCCCCCCCCHH	35.44	30266825
640	Phosphorylation	EPVDSDSTKTLTKQQ CCCCCCCCCCCCHHH	32.79	30266825
641	Sumoylation	PVDSDSTKTLTKQQS CCCCCCCCCCCHHHC	45.55	-
641	Sumoylation	PVDSDSTKTLTKQQS CCCCCCCCCCCHHHC	45.55	28112733
641	Ubiquitination	PVDSDSTKTLTKQQS CCCCCCCCCCCHHHC	45.55	-
645	Sumoylation	DSTKTLTKQQSTTFP CCCCCCCHHHCCCCC	49.83	-
645	Sumoylation	DSTKTLTKQQSTTFP CCCCCCCHHHCCCCC	49.83	28112733
645	Ubiquitination	DSTKTLTKQQSTTFP CCCCCCCHHHCCCCC	49.83	-
648	Phosphorylation	KTLTKQQSTTFPKNS CCCCHHHCCCCCCCH	27.24	28348404
649	Phosphorylation	TLTKQQSTTFPKNSA CCCHHHCCCCCCCHH	28.28	28348404
650	Phosphorylation	LTKQQSTTFPKNSAL CCHHHCCCCCCCHHH	43.09	27251275
655	Phosphorylation	STTFPKNSALKQDVK CCCCCCCHHHHHHHH	40.90	25599653
658	Sumoylation	FPKNSALKQDVKRTF CCCCHHHHHHHHHHH	44.14	-
658	Sumoylation	FPKNSALKQDVKRTF CCCCHHHHHHHHHHH	44.14	28112733
664	Phosphorylation	LKQDVKRTFGSTSQS HHHHHHHHHCCCCCC	26.99	25627689
667	Phosphorylation	DVKRTFGSTSQSSSF HHHHHHCCCCCCCCC	22.24	26434776
668	Phosphorylation	VKRTFGSTSQSSSFS HHHHHCCCCCCCCCH	31.03	26434776
669	Phosphorylation	KRTFGSTSQSSSFSK HHHHCCCCCCCCCHH	29.75	25159151
671	Phosphorylation	TFGSTSQSSSFSKIH HHCCCCCCCCCHHHH	27.93	26434776
672	Phosphorylation	FGSTSQSSSFSKIHK HCCCCCCCCCHHHHC	27.97	26434776
673	Phosphorylation	GSTSQSSSFSKIHKR CCCCCCCCCHHHHCC	38.49	23401153
675	Phosphorylation	TSQSSSFSKIHKRPH CCCCCCCHHHHCCHH	32.42	26434776
676	Sumoylation	SQSSSFSKIHKRPHR CCCCCCHHHHCCHHH	46.98	-
676	Sumoylation	SQSSSFSKIHKRPHR CCCCCCHHHHCCHHH	46.98	28112733
688	Methylation	PHRIQKARKSIAQSG HHHHHHHHHHHHHHC	40.05	115920585
689	Methylation	HRIQKARKSIAQSGV HHHHHHHHHHHHHCC	51.58	115920581
694	Phosphorylation	ARKSIAQSGVNMCNQ HHHHHHHHCCCCCCC	35.37	27067055
703	Phosphorylation	VNMCNQNSSPHKNVT CCCCCCCCCCCCCCE	35.17	27174698
704	Phosphorylation	NMCNQNSSPHKNVTI CCCCCCCCCCCCCEE	38.28	27174698
712	Sumoylation	PHKNVTIKSSVDQKP CCCCCEECCCCCCCC	27.58	-
712	Sumoylation	PHKNVTIKSSVDQKP CCCCCEECCCCCCCC	27.58	28112733
712	Ubiquitination	PHKNVTIKSSVDQKP CCCCCEECCCCCCCC	27.58	-
718	Sumoylation	IKSSVDQKPKYFHQA ECCCCCCCCCHHHHH	38.73	-
718	Sumoylation	IKSSVDQKPKYFHQA ECCCCCCCCCHHHHH	38.73	28112733
720	Ubiquitination	SSVDQKPKYFHQAAK CCCCCCCCHHHHHHH	68.53	-
720	Sumoylation	SSVDQKPKYFHQAAK CCCCCCCCHHHHHHH	68.53	28112733
727	Ubiquitination	KYFHQAAKEKSNAKA CHHHHHHHHHHCCCC	69.55	-
727	Sumoylation	KYFHQAAKEKSNAKA CHHHHHHHHHHCCCC	69.55	28112733
733	Sumoylation	AKEKSNAKANSHYLY HHHHHCCCCCHHHHH	52.96	-
733	Sumoylation	AKEKSNAKANSHYLY HHHHHCCCCCHHHHH	52.96	28112733
733	Ubiquitination	AKEKSNAKANSHYLY HHHHHCCCCCHHHHH	52.96	-
753	Phosphorylation	NYRMIKKSGESYPVH CEEEEECCCCCCCCC	42.67	25159151
757	Phosphorylation	IKKSGESYPVHFKKE EECCCCCCCCCCCHH	12.65	22461510
762	Sumoylation	ESYPVHFKKEEASSL CCCCCCCCHHHHCCC	44.38	-
762	Sumoylation	ESYPVHFKKEEASSL CCCCCCCCHHHHCCC	44.38	28112733
762	Ubiquitination	ESYPVHFKKEEASSL CCCCCCCCHHHHCCC	44.38	-
763	Sumoylation	SYPVHFKKEEASSLN CCCCCCCHHHHCCCC	60.90	28112733
791	Sumoylation	NFISDPHKPDAKRPE CCCCCCCCCCCCCCC	50.40	28112733
795	Sumoylation	DPHKPDAKRPESFKD CCCCCCCCCCCCHHH	75.71	28112733
817	Ubiquitination	RVIKESKKESSVGGE HHHHHHHHCCCCCCC	72.59	-
817	Sumoylation	RVIKESKKESSVGGE HHHHHHHHCCCCCCC	72.59	28112733
819	Phosphorylation	IKESKKESSVGGEDL HHHHHHCCCCCCCCH	38.92	25159151
820	Phosphorylation	KESKKESSVGGEDLD HHHHHCCCCCCCCHH	26.35	25159151
828	Phosphorylation	VGGEDLDSYPDFLHK CCCCCHHHCHHHHHH	45.95	25159151
835	Sumoylation	SYPDFLHKMTVVVLQ HCHHHHHHHHHHHHH	38.11	28112733
843	Ubiquitination	MTVVVLQKLNSAEKK HHHHHHHHCCCCCCC	45.54	21890473
843	Ubiquitination	MTVVVLQKLNSAEKK HHHHHHHHCCCCCCC	45.54	21890473
843	Sumoylation	MTVVVLQKLNSAEKK HHHHHHHHCCCCCCC	45.54	28112733
843 (in isoform 1)	Ubiquitination	-	45.54	21890473
843 (in isoform 2)	Ubiquitination	-	45.54	21890473
962	Sumoylation	WTDLSLEKKSCPYCP EECCCCCCCCCCCCC	56.11	28112733
963	Ubiquitination	TDLSLEKKSCPYCPA ECCCCCCCCCCCCCC	48.17	-
1000	Phosphorylation	YEARHVVSPEQIATS CHHEECCCHHHHHCC	22.94	23401153
1006	Phosphorylation	VSPEQIATSDKMQHF CCHHHHHCCCHHHHH	38.80	30266825
1007	Phosphorylation	SPEQIATSDKMQHFK CHHHHHCCCHHHHHH	26.64	30266825
1009	Ubiquitination	EQIATSDKMQHFKRT HHHHCCCHHHHHHHC	39.98	-
1009	Sumoylation	EQIATSDKMQHFKRT HHHHCCCHHHHHHHC	39.98	28112733
1016	Phosphorylation	KMQHFKRTGTGTPVK HHHHHHHCCCCCCHH	39.42	28176443
1018	O-linked_Glycosylation	QHFKRTGTGTPVKRV HHHHHCCCCCCHHHH	36.95	30379171
1018	Phosphorylation	QHFKRTGTGTPVKRV HHHHHCCCCCCHHHH	36.95	28176443
1020	Phosphorylation	FKRTGTGTPVKRVRK HHHCCCCCCHHHHHH	25.42	30576142
1023	"N6,N6-dimethyllysine"	TGTGTPVKRVRKAIE CCCCCCHHHHHHHHH	46.51	-
1023	Acetylation	TGTGTPVKRVRKAIE CCCCCCHHHHHHHHH	46.51	25953088
1023	Methylation	TGTGTPVKRVRKAIE CCCCCCHHHHHHHHH	46.51	-
1031	Ubiquitination	RVRKAIEKSETTSEH HHHHHHHHCCCCCHH	47.69	-
1031	Sumoylation	RVRKAIEKSETTSEH HHHHHHHHCCCCCHH	47.69	28112733
1068	Ubiquitination	LKRLGKTKWDAHKSP HHHHCCCCCHHHCCC	46.71	-
1074	Phosphorylation	TKWDAHKSPICVLNE CCCHHHCCCCHHHHH	15.05	22199227
1088	Sumoylation	EMMQNEEKYEKILKA HHHCCHHHHHHHHHH	53.16	28112733
1091	Sumoylation	QNEEKYEKILKALNS CCHHHHHHHHHHHHC	50.69	-
1091	Sumoylation	QNEEKYEKILKALNS CCHHHHHHHHHHHHC	50.69	-
1094	Sumoylation	EKYEKILKALNSRRI HHHHHHHHHHHCCCC	55.06	-
1094	Ubiquitination	EKYEKILKALNSRRI HHHHHHHHHHHCCCC	55.06	-
1094	Sumoylation	EKYEKILKALNSRRI HHHHHHHHHHHCCCC	55.06	28112733
1110	Ubiquitination	PRPFVAQKLASSDDF CCHHHHHHHHCCCCH	35.96	-
1110	Sumoylation	PRPFVAQKLASSDDF CCHHHHHHHHCCCCH	35.96	28112733
1113	Phosphorylation	FVAQKLASSDDFISQ HHHHHHHCCCCHHHC	44.74	20068231
1114	Phosphorylation	VAQKLASSDDFISQN HHHHHHCCCCHHHCC	35.28	20068231
1119	Phosphorylation	ASSDDFISQNVIPLE HCCCCHHHCCCCCHH	18.72	20068231
1128	Phosphorylation	NVIPLEAYRNGLKTE CCCCHHHHHCCCCCE	8.67	20068231
1133	Ubiquitination	EAYRNGLKTEALSVS HHHHCCCCCEEEECC	45.80	-
1133	Sumoylation	EAYRNGLKTEALSVS HHHHCCCCCEEEECC	45.80	28112733
1138	Phosphorylation	GLKTEALSVSASEEE CCCCEEEECCCCHHH	22.52	25627689
1157	Sumoylation	LNEYDETKPELPSGK HHHCCCCCCCCCCCC	34.15	28112733
1162	Phosphorylation	ETKPELPSGKKNQSL CCCCCCCCCCCCCCC	75.71	24719451
1165	Sumoylation	PELPSGKKNQSLTLI CCCCCCCCCCCCHHH	64.84	-
1165	Ubiquitination	PELPSGKKNQSLTLI CCCCCCCCCCCCHHH	64.84	-
1165	Sumoylation	PELPSGKKNQSLTLI CCCCCCCCCCCCHHH	64.84	28112733
1168	Phosphorylation	PSGKKNQSLTLIELL CCCCCCCCCHHHHHH	32.49	28555341
1176	Ubiquitination	LTLIELLKNKRMGEE CHHHHHHHCCCCCCC	73.39	21890473
1176	Ubiquitination	LTLIELLKNKRMGEE CHHHHHHHCCCCCCC	73.39	21890473
1176	Sumoylation	LTLIELLKNKRMGEE CHHHHHHHCCCCCCC	73.39	28112733
1176 (in isoform 1)	Ubiquitination	-	73.39	21890473
1176 (in isoform 2)	Ubiquitination	-	73.39	21890473
1178	Ubiquitination	LIELLKNKRMGEERN HHHHHHCCCCCCCCC	42.02	-
1186	Phosphorylation	RMGEERNSAISPQKI CCCCCCCCCCCHHHH	32.95	24732914
1189	Phosphorylation	EERNSAISPQKIHNQ CCCCCCCCHHHHCCH	22.46	23401153
1192	Ubiquitination	NSAISPQKIHNQTAR CCCCCHHHHCCHHHH	49.68	-
1192	Sumoylation	NSAISPQKIHNQTAR CCCCCHHHHCCHHHH	49.68	28112733
1197	Phosphorylation	PQKIHNQTARKRFVQ HHHHCCHHHHHHHHH	33.47	24732914
1205	Ubiquitination	ARKRFVQKCVLPLNE HHHHHHHHHCCCCCC	22.47	-
1205	Sumoylation	ARKRFVQKCVLPLNE HHHHHHHHHCCCCCC	22.47	28112733
1214	Phosphorylation	VLPLNEDSPLMYQPQ CCCCCCCCCCCCCCC	17.47	22199227
1234	Ubiquitination	MHSALDCKQKKSRSR HHHHHHHHCHHCCCC	65.89	-
1234	Sumoylation	MHSALDCKQKKSRSR HHHHHHHHCHHCCCC	65.89	28112733
1237	Ubiquitination	ALDCKQKKSRSRSGS HHHHHCHHCCCCCCC	48.91	-
1242	O-linked_Glycosylation	QKKSRSRSGSKKKML CHHCCCCCCCCCCEE	48.98	30379171
1259	Phosphorylation	PHGADEVYILRCRFC CCCCCEEEEEEECCC	7.68	25884760
1282	Ubiquitination	SVQEDWIKHLQRHIV CCCHHHHHHHHHHHH	33.73	-
1296	Phosphorylation	VNANLPRTGAGMVEV HHCCCCCCCCCHHHH	29.46	20068231
1304	Phosphorylation	GAGMVEVTSLLKKPA CCCHHHHHHHHCCCC	10.51	21406692
1305	Phosphorylation	AGMVEVTSLLKKPAS CCHHHHHHHHCCCCC	36.56	24719451
1308	Sumoylation	VEVTSLLKKPASITE HHHHHHHCCCCCCCH	63.10	28112733
1312	Phosphorylation	SLLKKPASITETSFS HHHCCCCCCCHHHHH	38.27	28450419
1314	Phosphorylation	LKKPASITETSFSLL HCCCCCCCHHHHHHH	30.62	28450419
1316	Phosphorylation	KPASITETSFSLLMA CCCCCCHHHHHHHHH	26.82	28450419
1317	Phosphorylation	PASITETSFSLLMAE CCCCCHHHHHHHHHH	13.45	28450419
1319	Phosphorylation	SITETSFSLLMAEAA CCCHHHHHHHHHHHH	21.99	28450419
1327	Phosphorylation	LLMAEAAS------- HHHHHHHC-------	48.04	28111955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZN644_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZN644_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZN644_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZRAB2_HUMAN	ZRANB2	physical	22939629
ACV1B_HUMAN	ACVR1B	physical	26496610
CSPG4_HUMAN	CSPG4	physical	26496610
ZMYM2_HUMAN	ZMYM2	physical	26496610
CDYL_HUMAN	CDYL	physical	26496610
ATP9A_HUMAN	ATP9A	physical	26496610
EHMT2_HUMAN	EHMT2	physical	26496610
ADNP_HUMAN	ADNP	physical	26496610
TECT3_HUMAN	TCTN3	physical	26496610
URFB1_HUMAN	UHRF1BP1	physical	26496610
PAR16_HUMAN	PARP16	physical	26496610
WIZ_HUMAN	WIZ	physical	26496610
EHMT1_HUMAN	EHMT1	physical	26496610
CHAP1_HUMAN	CHAMP1	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
614167	Myopia 21, autosomal dominant (MYP21)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZN644_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-309 AND SER-1000, ANDMASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1000, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1189, AND MASSSPECTROMETRY.	15302935 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-640, AND MASSSPECTROMETRY.	19413330 [Abstract]