dbPTM

ANR12_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ANR12_HUMAN
UniProt AC	Q6UB98
Protein Name	Ankyrin repeat domain-containing protein 12
Gene Name	ANKRD12
Organism	Homo sapiens (Human).
Sequence Length	2062
Subcellular Localization	Nucleus .
Protein Description	May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation..
Protein Sequence	MPKSGFTKPIQSENSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENEKPGLSSRSVSMISVASSEDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPERIKPPYANRLSTSHLRSSSVEDVKLIISEGRPTIEVRRCSMPSVICEHTKQFQTISEESNQGSLLTVPGDTSPSPKPEVFSNVPERDLSNVSNIHSSFATSPTGASNSKYVSADRNLIKNTAPVNTVMDSPVHLEPSSQVGVIQNKSWEMPVDRLETLSTRDFICPNSNIPDQESSLQSFCNSENKVLKENADFLSLRQTELPGNSCAQDPASFMPPQQPCSFPSQSLSDAESISKHMSLSYVANQEPGILQQKNAVQIISSALDTDNESTKDTENTFVLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLNTHYAFSKLTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHLSRCDSDLCEMNAGMPKGNLNEQDPKHCPESEKCLLSIEDEESQQSILSSLENHSQQSTQPEMHKYGQLVKVELEENAEDDKTENQIPQRMTRNKANTMANQSKQILASCTLLSEKDSESSSPRGRIRLTEDDDPQIHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MPKSGFTKPIQ ----CCCCCCCCCCC	50.28	23663014
7	Phosphorylation	-MPKSGFTKPIQSEN -CCCCCCCCCCCCCC	39.16	23663014
12	Phosphorylation	GFTKPIQSENSDSDS CCCCCCCCCCCCCCC	39.19	23663014
15	Phosphorylation	KPIQSENSDSDSNMV CCCCCCCCCCCCCCC	34.15	23401153
17	Phosphorylation	IQSENSDSDSNMVEK CCCCCCCCCCCCCCC	42.64	23663014
19	Phosphorylation	SENSDSDSNMVEKPY CCCCCCCCCCCCCCC	30.67	28450419
26	Phosphorylation	SNMVEKPYGRKSKDK CCCCCCCCCCCCHHH	40.40	28111955
36	O-linked_Glycosylation	KSKDKIASYSKTPKI CCHHHHHHCCCCCCC	33.15	30379171
39	Acetylation	DKIASYSKTPKIERS HHHHHCCCCCCCCHH	61.69	19608861
56	Phosphorylation	SKEMKEKSSMKRKLP CHHHHHHHHCCCCCC	36.43	26074081
57	Phosphorylation	KEMKEKSSMKRKLPF HHHHHHHHCCCCCCC	39.12	26074081
65	Phosphorylation	MKRKLPFTISPSRNE CCCCCCCCCCCCCCC	20.71	30266825
67	Phosphorylation	RKLPFTISPSRNEER CCCCCCCCCCCCCCC	17.48	30266825
67 (in isoform 2)	Phosphorylation	-	17.48	25159151
69	Phosphorylation	LPFTISPSRNEERDS CCCCCCCCCCCCCCC	40.73	30266825
76	Phosphorylation	SRNEERDSDTDSDPG CCCCCCCCCCCCCCC	48.94	26074081
76 (in isoform 2)	Phosphorylation	-	48.94	25849741
78 (in isoform 2)	Phosphorylation	-	41.16	20873877
120	Phosphorylation	KEAGNKKSTPVSILF HHHCCCCCCCHHHEE	39.28	21712546
121	Phosphorylation	EAGNKKSTPVSILFG HHCCCCCCCHHHEEC	36.27	25159151
124	Phosphorylation	NKKSTPVSILFGYPL CCCCCCHHHEECCCC	18.12	21712546
132	Phosphorylation	ILFGYPLSERKQMAL HEECCCCCHHHHHHH	30.74	25159151
149	Phosphorylation	QMTARDNSPDSTPNH HHHCCCCCCCCCCCC	34.08	23401153
152	Phosphorylation	ARDNSPDSTPNHPSQ CCCCCCCCCCCCCCC	49.50	30266825
153	Phosphorylation	RDNSPDSTPNHPSQT CCCCCCCCCCCCCCC	35.17	30266825
158	Phosphorylation	DSTPNHPSQTTPAQK CCCCCCCCCCCCCCC	32.38	30266825
160	Phosphorylation	TPNHPSQTTPAQKKT CCCCCCCCCCCCCCC	38.80	23403867
161	Phosphorylation	PNHPSQTTPAQKKTP CCCCCCCCCCCCCCC	14.69	23403867
167	Phosphorylation	TTPAQKKTPSSSSRQ CCCCCCCCCCCCHHH	35.12	25690035
170	Phosphorylation	AQKKTPSSSSRQKDK CCCCCCCCCHHHHHH	33.27	25690035
300	Ubiquitination	TEELELLLKREVPLS HHHHHHHHHCCCCCC	8.42	22817900
302	Ubiquitination	ELELLLKREVPLSDD HHHHHHHCCCCCCCC	50.55	21963094
304	Ubiquitination	ELLLKREVPLSDDDE HHHHHCCCCCCCCCC	7.21	22817900
306	Ubiquitination	LLKREVPLSDDDESY HHHCCCCCCCCCCCC	12.08	22817900
350	Phosphorylation	ESKQILPSKTPLPSA CCCCCCCCCCCCCCC	45.79	24719451
352	Phosphorylation	KQILPSKTPLPSALD CCCCCCCCCCCCCCC	34.10	26074081
356	Phosphorylation	PSKTPLPSALDEYEF CCCCCCCCCCCCCCC	49.50	26074081
361	Phosphorylation	LPSALDEYEFKDDDD CCCCCCCCCCCCCCH	26.74	26074081
380	Ubiquitination	KMIDDRHILRKEQRK HHHHHHHHHHHHHHH	4.08	22817900
382	Ubiquitination	IDDRHILRKEQRKEN HHHHHHHHHHHHHHC	39.60	21963094
384	Ubiquitination	DRHILRKEQRKENEP HHHHHHHHHHHHCCC	49.54	22817900
386	Ubiquitination	HILRKEQRKENEPEA HHHHHHHHHHCCCHH	49.71	22817900
406	Phosphorylation	FAKQEKAFYPKSFKS HHHHHHHHCCCCCCC	18.59	33259812
419	Phosphorylation	KSKKQKPSRVLYSST CCCCCCCCCEEECCC	41.90	22468782
423	Phosphorylation	QKPSRVLYSSTESSD CCCCCEEECCCCCCH	9.56	20873877
424	Phosphorylation	KPSRVLYSSTESSDE CCCCEEECCCCCCHH	26.99	20873877
425	Phosphorylation	PSRVLYSSTESSDEE CCCEEECCCCCCHHH	23.72	20873877
426	Phosphorylation	SRVLYSSTESSDEEA CCEEECCCCCCHHHH	33.67	20873877
428	Phosphorylation	VLYSSTESSDEEALQ EEECCCCCCHHHHHH	43.08	20873877
429	Phosphorylation	LYSSTESSDEEALQN EECCCCCCHHHHHHC	42.69	72245481
441	Phosphorylation	LQNKKISTSCSVIPE HHCCCCCCCCEECCC	36.91	46163807
442	Phosphorylation	QNKKISTSCSVIPET HCCCCCCCCEECCCC	9.52	46163795
449	Phosphorylation	SCSVIPETSNSDMQT CCEECCCCCCCCCCC	28.05	46163813
498	Phosphorylation	EKEGKENTRITNLTV HHHCCCCCEEEEEEE	25.25	30576142
504	Phosphorylation	NTRITNLTVNTGLDC CCEEEEEEECCCCCC	17.49	30576142
507	Phosphorylation	ITNLTVNTGLDCSEK EEEEEECCCCCCCHH	34.48	30576142
524	Phosphorylation	EEGNFRKSFSPKDDT CCCCCCCCCCCCCCC	27.05	30108239
526	Phosphorylation	GNFRKSFSPKDDTSL CCCCCCCCCCCCCEE	37.82	28450419
531	Phosphorylation	SFSPKDDTSLHLFHI CCCCCCCCEEEEEEE	43.23	23403867
532	Phosphorylation	FSPKDDTSLHLFHIS CCCCCCCEEEEEEEC	22.30	23403867
539	Phosphorylation	SLHLFHISTGKSPKH EEEEEEECCCCCCCC	23.65	23403867
540	Phosphorylation	LHLFHISTGKSPKHS EEEEEECCCCCCCCC	48.29	23401153
543	Phosphorylation	FHISTGKSPKHSCGL EEECCCCCCCCCCCC	40.29	23401153
555	Phosphorylation	CGLSEKQSTPLKQEH CCCCCCCCCCCCCHH	42.96	28122231
556	Phosphorylation	GLSEKQSTPLKQEHT CCCCCCCCCCCCHHC	30.10	28348404
565	Phosphorylation	LKQEHTKTCLSPGSS CCCHHCCCCCCCCCC	21.60	30266825
568	Phosphorylation	EHTKTCLSPGSSEMS HHCCCCCCCCCCCCC	29.39	30266825
571	Phosphorylation	KTCLSPGSSEMSLQP CCCCCCCCCCCCCCC	26.89	30266825
572	Phosphorylation	TCLSPGSSEMSLQPD CCCCCCCCCCCCCCC	43.14	30266825
575	Phosphorylation	SPGSSEMSLQPDLVR CCCCCCCCCCCCEEE	21.57	30266825
630	Phosphorylation	KIKDEDHSPTFENSD CCCCCCCCCCCCCCC	37.65	23401153
632	Phosphorylation	KDEDHSPTFENSDCT CCCCCCCCCCCCCCC	46.74	25849741
636	Phosphorylation	HSPTFENSDCTLKKM CCCCCCCCCCCCEEC	27.19	27251275
639	Phosphorylation	TFENSDCTLKKMDKE CCCCCCCCCEECCCC	46.75	27251275
648	Ubiquitination	KKMDKEGKTLKKHKL EECCCCCCHHHHHHC	52.34	22817900
650	Ubiquitination	MDKEGKTLKKHKLKH CCCCCCHHHHHHCHH	8.73	21963094
652	Ubiquitination	KEGKTLKKHKLKHKE CCCCHHHHHHCHHHH	49.43	21963094
654	Ubiquitination	GKTLKKHKLKHKERE CCHHHHHHCHHHHHH	69.02	22817900
656	Ubiquitination	TLKKHKLKHKEREKE HHHHHHCHHHHHHHH	58.39	22817900
671	Ubiquitination	KHKKEIEGEKEKYKT HHHHHHHHHHHHHCC	57.87	22817900
673	Acetylation	KKEIEGEKEKYKTKD HHHHHHHHHHHCCHH	71.06	7664477
673	Ubiquitination	KKEIEGEKEKYKTKD HHHHHHHHHHHCCHH	71.06	21963094
675	Ubiquitination	EIEGEKEKYKTKDSA HHHHHHHHHCCHHHH	64.21	21963094
677	Ubiquitination	EGEKEKYKTKDSAKE HHHHHHHCCHHHHHH	61.23	22817900
679	Ubiquitination	EKEKYKTKDSAKELQ HHHHHCCHHHHHHHH	45.60	22817900
688	Phosphorylation	SAKELQRSVEFDREF HHHHHHHHHHHCHHH	17.03	101546159
760	Acetylation	KIKKESEKSFREEKI HHHHHHHHHHHHHHH	65.26	7708357
861	Phosphorylation	EKDKLDLSECVDKIK HHHCCCHHHHHHHHH	28.72	22817900
891	Phosphorylation	EGEKSKNTAAIKKTD CCCCCCCCCCHHCCC	22.62	18678407
897	Phosphorylation	NTAAIKKTDDREKSR CCCCHHCCCHHHHHH	37.82	18678417
900	Methylation	AIKKTDDREKSREKM CHHCCCHHHHHHHHH	56.93	-
903	Phosphorylation	KTDDREKSREKMDRK CCCHHHHHHHHHHHH	40.70	18678427
925	Phosphorylation	KERHLAESKEKHLME HHHHHHHHHHHHHHH	40.27	26074081
926	Ubiquitination	ERHLAESKEKHLMEK HHHHHHHHHHHHHHH	63.39	-
928	"N6,N6-dimethyllysine"	HLAESKEKHLMEKKN HHHHHHHHHHHHHHC	45.86	-
928	Methylation	HLAESKEKHLMEKKN HHHHHHHHHHHHHHC	45.86	23644510
938	Phosphorylation	MEKKNKQSDNSEYSK HHHHCCCCCCCCCCH	40.13	26074081
941	Phosphorylation	KNKQSDNSEYSKSEK HCCCCCCCCCCHHHH	42.79	26074081
943	Phosphorylation	KQSDNSEYSKSEKGK CCCCCCCCCHHHHCC	22.63	26074081
944	Phosphorylation	QSDNSEYSKSEKGKN CCCCCCCCHHHHCCC	26.17	26074081
946	Phosphorylation	DNSEYSKSEKGKNKE CCCCCCHHHHCCCHH	38.30	11663501
964	Phosphorylation	ELDKKEKSRDKESIN HHHHHHHHCCHHHCC	46.96	11663509
976	Acetylation	SINITNSKHIQEEKK HCCCCCCHHHHHHHH	46.96	7305715
987	Ubiquitination	EEKKSSIVDGNKAQH HHHHHCCCCCCHHHC	9.24	29967540
1010	Ubiquitination	KTKDEPLKTPDGKEK HCCCCCCCCCCCCCC	69.59	29967540
1011	Phosphorylation	TKDEPLKTPDGKEKD CCCCCCCCCCCCCCC	34.00	54887051
1034	Trimethylation	YKERDKHKDKIQINS HHHHHHHHCHHHHHH	67.47	-
1034	Acetylation	YKERDKHKDKIQINS HHHHHHHHCHHHHHH	67.47	7851251
1034	Methylation	YKERDKHKDKIQINS HHHHHHHHCHHHHHH	67.47	-
1036	Trimethylation	ERDKHKDKIQINSLL HHHHHHCHHHHHHHH	41.11	-
1036	Acetylation	ERDKHKDKIQINSLL HHHHHHCHHHHHHHH	41.11	7851261
1036	Methylation	ERDKHKDKIQINSLL HHHHHHCHHHHHHHH	41.11	-
1041	Phosphorylation	KDKIQINSLLKLKSE HCHHHHHHHHHHHHC	36.39	24719451
1047	Phosphorylation	NSLLKLKSEADKPKP HHHHHHHHCCCCCCC	48.75	24719451
1056	Phosphorylation	ADKPKPKSSPASKDT CCCCCCCCCCCCCCC	50.51	24719451
1057	Phosphorylation	DKPKPKSSPASKDTR CCCCCCCCCCCCCCC	30.52	24719451
1078	Phosphorylation	VNDDLMQTSFERMLS CCCHHHHHHHHHHHC	22.78	24719451
1079	Phosphorylation	NDDLMQTSFERMLSL CCHHHHHHHHHHHCC	14.28	50565329
1085	Phosphorylation	TSFERMLSLKDLEIE HHHHHHHCCHHHHHH	24.83	46163753
1129	Phosphorylation	DKEKTKHTPTESKNK CHHHCCCCCCCHHCH	33.20	23312004
1131	Phosphorylation	EKTKHTPTESKNKEL HHCCCCCCCHHCHHH	54.79	23312004
1133	Phosphorylation	TKHTPTESKNKELTR CCCCCCCHHCHHHHC	43.96	23312004
1141	Phosphorylation	KNKELTRSKSSEVTD HCHHHHCCCCHHCHH	31.49	25690035
1143	Phosphorylation	KELTRSKSSEVTDAY HHHHCCCCHHCHHHH	32.74	25159151
1144	Phosphorylation	ELTRSKSSEVTDAYT HHHCCCCHHCHHHHH	39.56	25262027
1147	Phosphorylation	RSKSSEVTDAYTKEK CCCCHHCHHHHHCCC	15.74	28450419
1150	Phosphorylation	SSEVTDAYTKEKQPK CHHCHHHHHCCCCCC	22.58	23312004
1151	Phosphorylation	SEVTDAYTKEKQPKD HHCHHHHHCCCCCCC	34.15	68741329
1166	Phosphorylation	AVSNRSQSVDTKNVM CCCCCCCCCCCCCCE	24.17	25159151
1174	Phosphorylation	VDTKNVMTLGKSSFV CCCCCCEECCCHHCC	28.24	29449344
1178	Phosphorylation	NVMTLGKSSFVSDNS CCEECCCHHCCCCCC	27.49	26074081
1179	Phosphorylation	VMTLGKSSFVSDNSL CEECCCHHCCCCCCC	32.90	26074081
1182	Phosphorylation	LGKSSFVSDNSLNRS CCCHHCCCCCCCCCC	29.12	23401153
1185	Phosphorylation	SSFVSDNSLNRSPRS HHCCCCCCCCCCCCC	31.82	23401153
1189	Phosphorylation	SDNSLNRSPRSENEK CCCCCCCCCCCCCCC	24.48	23401153
1192	Phosphorylation	SLNRSPRSENEKPGL CCCCCCCCCCCCCCC	48.43	23312004
1196	Ubiquitination	SPRSENEKPGLSSRS CCCCCCCCCCCCCCC	56.84	-
1200	Phosphorylation	ENEKPGLSSRSVSMI CCCCCCCCCCCEEEE	29.62	28857561
1201	Phosphorylation	NEKPGLSSRSVSMIS CCCCCCCCCCEEEEE	33.35	28857561
1255	Phosphorylation	PFLSIAKSPALHERE CCCHHHCCHHHCHHH	13.34	26657352
1288	Phosphorylation	LSTSHLRSSSVEDVK CCCCCCCCCCHHHHE	33.07	28102081
1289	Phosphorylation	STSHLRSSSVEDVKL CCCCCCCCCHHHHEE	31.78	24719451
1290	Phosphorylation	TSHLRSSSVEDVKLI CCCCCCCCHHHHEEE	30.67	28348404
1311	Phosphorylation	TIEVRRCSMPSVICE EEEEEECCCCHHHCC	31.73	23401153
1314	Phosphorylation	VRRCSMPSVICEHTK EEECCCCHHHCCCCC	18.57	29978859
1320	Phosphorylation	PSVICEHTKQFQTIS CHHHCCCCCCEEEEC	12.30	50565321
1334	Phosphorylation	SEESNQGSLLTVPGD CCHHCCCCCEEECCC	15.50	113322175
1337	Phosphorylation	SNQGSLLTVPGDTSP HCCCCCEEECCCCCC	29.92	26074081
1342	Phosphorylation	LLTVPGDTSPSPKPE CEEECCCCCCCCCCC	48.75	26657352
1343	Phosphorylation	LTVPGDTSPSPKPEV EEECCCCCCCCCCCH	28.28	27050516
1345	Phosphorylation	VPGDTSPSPKPEVFS ECCCCCCCCCCCHHC	45.37	27050516
1349	Phosphorylation	TSPSPKPEVFSNVPE CCCCCCCCHHCCCCH	63.42	32142685
1363	Phosphorylation	ERDLSNVSNIHSSFA HHHHCCCCCCCHHCC	34.03	30108239
1367	Phosphorylation	SNVSNIHSSFATSPT CCCCCCCHHCCCCCC	24.29	23401153
1368	Phosphorylation	NVSNIHSSFATSPTG CCCCCCHHCCCCCCC	12.53	29255136
1371	Phosphorylation	NIHSSFATSPTGASN CCCHHCCCCCCCCCC	32.98	29255136
1372	Phosphorylation	IHSSFATSPTGASNS CCHHCCCCCCCCCCC	19.62	29255136
1374	Phosphorylation	SSFATSPTGASNSKY HHCCCCCCCCCCCCC	45.18	23663014
1377	Phosphorylation	ATSPTGASNSKYVSA CCCCCCCCCCCCCCC	42.87	23663014
1379	Phosphorylation	SPTGASNSKYVSADR CCCCCCCCCCCCCCC	23.91	23663014
1381	Phosphorylation	TGASNSKYVSADRNL CCCCCCCCCCCCCCC	10.23	26074081
1392	Phosphorylation	DRNLIKNTAPVNTVM CCCCCCCCCCCCCCC	27.60	29978859
1397	Phosphorylation	KNTAPVNTVMDSPVH CCCCCCCCCCCCCCC	19.90	30108239
1401	Phosphorylation	PVNTVMDSPVHLEPS CCCCCCCCCCCCCCC	15.66	25159151
1408	Phosphorylation	SPVHLEPSSQVGVIQ CCCCCCCCCCEEEEE	24.83	28450419
1409	Phosphorylation	PVHLEPSSQVGVIQN CCCCCCCCCEEEEEC	39.33	28450419
1430	Phosphorylation	VDRLETLSTRDFICP CCHHHHCCCCCCCCC	28.90	24719451
1537	Phosphorylation	IISSALDTDNESTKD HHHHHHCCCCCCCCC	41.39	25159151
1564	Phosphorylation	TDAFVPVYSDSTIQE CCCEEEEECCCCCCC	10.74	29978859
1565	Phosphorylation	DAFVPVYSDSTIQEA CCEEEEECCCCCCCC	25.89	29978859
1567	Phosphorylation	FVPVYSDSTIQEASP EEEEECCCCCCCCCC	22.82	28348404
1568	Phosphorylation	VPVYSDSTIQEASPN EEEECCCCCCCCCCC	31.50	28348404
1573	Phosphorylation	DSTIQEASPNFEKAY CCCCCCCCCCCHHHE	21.44	25159151
1580	Phosphorylation	SPNFEKAYTLPVLPS CCCCHHHEECCCCCC	21.63	27642862
1639	Phosphorylation	EKENKLESLVLTHLS HHHHHHHHHHHHHHH	33.93	28555341
1646	Phosphorylation	SLVLTHLSRCDSDLC HHHHHHHHHCCHHHH	24.21	46163765
1650	Phosphorylation	THLSRCDSDLCEMNA HHHHHCCHHHHHHCC	35.79	27251275
1687	Phosphorylation	LSIEDEESQQSILSS EECCCHHHHHHHHHH	31.32	46163771
1690	Phosphorylation	EDEESQQSILSSLEN CCHHHHHHHHHHHHH	20.19	46163777
1747	Phosphorylation	ANTMANQSKQILASC HHHHHHHHHHHHHHH	26.74	27251275
1758	Phosphorylation	LASCTLLSEKDSESS HHHHHCCCCCCCCCC	45.79	24719451
1762	Phosphorylation	TLLSEKDSESSSPRG HCCCCCCCCCCCCCC	50.90	24719451
1783	Ubiquitination	DDDPQIHHPRKRKVS CCCCCCCCCCCCCCC	26.03	29967540
1790	Phosphorylation	HPRKRKVSRVPQPVQ CCCCCCCCCCCCCCC	30.51	24719451
1799	Phosphorylation	VPQPVQVSPSLLQAK CCCCCCCCHHHHHHH	7.53	30266825
1801	Phosphorylation	QPVQVSPSLLQAKEK CCCCCCHHHHHHHHH	33.92	30266825
1806	Ubiquitination	SPSLLQAKEKTQQSL CHHHHHHHHHHHHHH	46.94	29967540
1809	Phosphorylation	LLQAKEKTQQSLAAI HHHHHHHHHHHHHHH	32.69	24114839
1812	Phosphorylation	AKEKTQQSLAAIVDS HHHHHHHHHHHHHHH	15.34	24114839
1839	Phosphorylation	RANPYFEYLHIRKKI CCCHHHHHHHHHHHH	8.15	22817900
1855	Phosphorylation	EKRKLLCSVIPQAPQ HHHHHHHHHCCCCCC	24.05	46163783
1863	Phosphorylation	VIPQAPQYYDEYVTF HCCCCCCCCCEEEEE	16.30	24043423
1864	Phosphorylation	IPQAPQYYDEYVTFN CCCCCCCCCEEEEEC	9.32	22817900
1867	Phosphorylation	APQYYDEYVTFNGSY CCCCCCEEEEECCEE	11.24	24043423
1869	Phosphorylation	QYYDEYVTFNGSYLL CCCCEEEEECCEEEE	15.52	24043423
1873	Phosphorylation	EYVTFNGSYLLDGNP EEEEECCEEEECCCC	17.45	24043423
1874	Phosphorylation	YVTFNGSYLLDGNPL EEEECCEEEECCCCC	16.81	24043423
1882	Phosphorylation	LLDGNPLSKICIPTI EECCCCCCCCCCCCC	22.64	24043423
1927	Phosphorylation	EREKLIVSNEQEVLR HHHEEEECCHHHHHH	27.88	46163789
1951	Phosphorylation	ANQTLPFSACTVLLD HCCCCCCCCEEEEEE	22.09	26434552
1954	Phosphorylation	TLPFSACTVLLDAEV CCCCCCEEEEEEEEE	17.57	26434552

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
76	S	Phosphorylation	Kinase	CHEK1	O14757	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ANR12_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ANR12_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TADA3_HUMAN	TADA3	physical	18377363
HDAC3_HUMAN	HDAC3	physical	18377363
SGPL1_HUMAN	SGPL1	physical	26186194
GAPR1_HUMAN	GLIPR2	physical	26186194
PHYIP_HUMAN	PHYHIP	physical	26186194
FYN_HUMAN	FYN	physical	26186194
YES_HUMAN	YES1	physical	26186194
ULBP2_HUMAN	ULBP2	physical	26186194
SLIT2_HUMAN	SLIT2	physical	26186194
HIF1N_HUMAN	HIF1AN	physical	26186194
GBB4_HUMAN	GNB4	physical	26186194
SGPL1_HUMAN	SGPL1	physical	28514442
PHYIP_HUMAN	PHYHIP	physical	28514442
ULBP2_HUMAN	ULBP2	physical	28514442
SLIT2_HUMAN	SLIT2	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ANR12_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-39, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149, AND MASSSPECTROMETRY.	18669648 [Abstract]
"Phosphoproteome of resting human platelets."; Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J.,Schuetz C., Walter U., Gambaryan S., Sickmann A.; J. Proteome Res. 7:526-534(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-861, AND MASSSPECTROMETRY.	18088087 [Abstract]