ESR1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ESR1_HUMAN
• UniProt AC: P03372
• Protein Name: Estrogen receptor
• Gene Name: ESR1
• Organism: Homo sapiens (Human).
• Sequence Length: 595
• Subcellular Localization: Isoform 1: Nucleus . Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . A minor fraction is associated with the inner membrane.; Isoform 3: Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Ce
• Protein Description: Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences. Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP. Can activate the transcriptional activity of TFF1. Also mediates membrane-initiated estrogen signaling involving various kinase cascades. Isoform 3 is involved in activation of NOS3 and endothelial nitric oxide production. Isoforms lacking one or several functional domains are thought to modulate transcriptional activity by competitive ligand or DNA binding and/or heterodimerization with the full-length receptor. Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3. Isoform 3 can bind to ERE and inhibit isoform 1..
• Protein Sequence: MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTMTLHTKA ------CCCEEECHH	20.90	18187866
4	Phosphorylation	----MTMTLHTKASG ----CCCEEECHHHH	13.25	18187866
7	Phosphorylation	-MTMTLHTKASGMAL -CCCEEECHHHHHHH	31.27	18187866
8	Acetylation	MTMTLHTKASGMALL CCCEEECHHHHHHHH	29.79	18984578
10	O-linked_Glycosylation	MTLHTKASGMALLHQ CEEECHHHHHHHHHH	30.56	UniProtKB CARBOHYD
10	Phosphorylation	MTLHTKASGMALLHQ CEEECHHHHHHHHHH	30.56	11226831
10	O-linked_Glycosylation	MTLHTKASGMALLHQ CEEECHHHHHHHHHH	30.56	11226831
32	Acetylation	PLNRPQLKIPLERPL CCCCCCCCCCCCCCC	36.71	62188851
46	Phosphorylation	LGEVYLDSSKPAVYN CCEEECCCCCCCEEC	37.35	20043841
47	Phosphorylation	GEVYLDSSKPAVYNY CEEECCCCCCCEECC	42.18	20043841
52	Phosphorylation	DSSKPAVYNYPEGAA CCCCCCEECCCCCCC	15.87	20101225
102	Phosphorylation	GGFPPLNSVSPSPLM CCCCCCCCCCCCCEE	31.49	10949034
104	Phosphorylation	FPPLNSVSPSPLMLL CCCCCCCCCCCEEEC	21.34	17068199
106	Phosphorylation	PLNSVSPSPLMLLHP CCCCCCCCCEEECCC	24.14	17068199
118	Phosphorylation	LHPPPQLSPFLQPHG CCCCCCCCCCCCCCC	14.36	16113102
154	Phosphorylation	PAFYRPNSDNRRQGG CCCCCCCCCCCCCCH	38.66	18367407
167	Phosphorylation	GGRERLASTNDKGSM CHHHCHHHCCCCCCH	32.13	17068199
171	"N6,N6-dimethyllysine"	RLASTNDKGSMAMES CHHHCCCCCCHHHHH	55.76	-
171	Acetylation	RLASTNDKGSMAMES CHHHCCCCCCHHHHH	55.76	62188855
171	Methylation	RLASTNDKGSMAMES CHHHCCCCCCHHHHH	55.76	-
171	Sumoylation	RLASTNDKGSMAMES CHHHCCCCCCHHHHH	55.76	-
180	"N6,N6-dimethyllysine"	SMAMESAKETRYCAV CHHHHHHHHHCEEEE	69.74	-
180	Methylation	SMAMESAKETRYCAV CHHHHHHHHHCEEEE	69.74	-
180	Sumoylation	SMAMESAKETRYCAV CHHHHHHHHHCEEEE	69.74	-
201	Phosphorylation	GYHYGVWSCEGCKAF CCCCEEEECCHHHHH	10.41	9528769
212	Phosphorylation	CKAFFKRSIQGHNDY HHHHHHHHHCCCCCC	21.61	22266331
219	Phosphorylation	SIQGHNDYMCPATNQ HHCCCCCCCCCCCCC	13.11	20101225
236	Phosphorylation	IDKNRRKSCQACRLR ECCCHHHCCHHHHHH	15.06	17068199
244	Acetylation	CQACRLRKCYEVGMM CHHHHHHHHHHHHCC	45.84	30051005
252	Acetylation	CYEVGMMKGGIRKDR HHHHHCCCCCCCCCC	45.13	30050999
260	Methylation	GGIRKDRRGGRMLKH CCCCCCCCCCCCCEE	63.15	24498420
260	Asymmetric dimethylarginine	GGIRKDRRGGRMLKH CCCCCCCCCCCCCEE	63.15	-
266	Sumoylation	RRGGRMLKHKRQRDD CCCCCCCEECCCCCC	37.42	-
266	Sumoylation	RRGGRMLKHKRQRDD CCCCCCCEECCCCCC	37.42	-
266	Acetylation	RRGGRMLKHKRQRDD CCCCCCCEECCCCCC	37.42	20167786
266	Methylation	RRGGRMLKHKRQRDD CCCCCCCEECCCCCC	37.42	-
268	Sumoylation	GGRMLKHKRQRDDGE CCCCCEECCCCCCCC	48.95	-
268	Acetylation	GGRMLKHKRQRDDGE CCCCCEECCCCCCCC	48.95	16497729
268	Sumoylation	GGRMLKHKRQRDDGE CCCCCEECCCCCCCC	48.95	-
277	Dimethylation	QRDDGEGRGEVGSAG CCCCCCCCCCCCCHH	33.52	-
277	Methylation	QRDDGEGRGEVGSAG CCCCCCCCCCCCCHH	33.52	-
282	Phosphorylation	EGRGEVGSAGDMRAA CCCCCCCCHHHHCHH	33.96	20418363
294	Phosphorylation	RAANLWPSPLMIKRS CHHHCCCCCEEEECC	21.05	20418363
299	Acetylation	WPSPLMIKRSKKNSL CCCCEEEECCCCCCE	36.33	11279135
299	Sumoylation	WPSPLMIKRSKKNSL CCCCEEEECCCCCCE	36.33	-
299	Sumoylation	WPSPLMIKRSKKNSL CCCCEEEECCCCCCE	36.33	-
302	Acetylation	PLMIKRSKKNSLALS CEEEECCCCCCEEEE	61.07	11279135
302	Sumoylation	PLMIKRSKKNSLALS CEEEECCCCCCEEEE	61.07	-
302	Methylation	PLMIKRSKKNSLALS CEEEECCCCCCEEEE	61.07	18471979
302	Ubiquitination	PLMIKRSKKNSLALS CEEEECCCCCCEEEE	61.07	17392432
303	Sumoylation	LMIKRSKKNSLALSL EEEECCCCCCEEEEC	53.68	-
303	Acetylation	LMIKRSKKNSLALSL EEEECCCCCCEEEEC	53.68	11279135
305	Phosphorylation	IKRSKKNSLALSLTA EECCCCCCEEEECCH	24.73	17068199
311	Phosphorylation	NSLALSLTADQMVSA CCEEEECCHHHHHHH	25.47	20418363
328	Phosphorylation	DAEPPILYSEYDPTR CCCCCEEEECCCCCC	10.52	26074081
329	Phosphorylation	AEPPILYSEYDPTRP CCCCEEEECCCCCCC	26.66	26074081
341	Phosphorylation	TRPFSEASMMGLLTN CCCCCHHHHHHHHHH	12.78	-
401	Methylation	RSMEHPGKLLFAPNL HHCCCCCCEEECCCE	46.60	-
401	"N6,N6-dimethyllysine"	RSMEHPGKLLFAPNL HHCCCCCCEEECCCE	46.60	-
447	S-palmitoylation	LQGEEFVCLKSIILL CCCCCEEEEEEEHHH	4.87	15033483
472	Sumoylation	TLKSLEEKDHIHRVL HHHHHHHHHHHHHHH	45.27	-
472	Acetylation	TLKSLEEKDHIHRVL HHHHHHHHHHHHHHH	45.27	18984578
472	Sumoylation	TLKSLEEKDHIHRVL HHHHHHHHHHHHHHH	45.27	-
485	Phosphorylation	VLDKITDTLIHLMAK HHHHHHHHHHHHHHH	20.97	-
537	Phosphorylation	CKNVVPLYDLLLEML CCCCCHHHHHHHHHH	9.85	12554772
537	Dephosphorylation	CKNVVPLYDLLLEML CCCCCHHHHHHHHHH	9.85	7539106
554	Phosphorylation	HRLHAPTSRGGASVE HCCCCCCCCCCCCCC	28.06	18984578
559	Phosphorylation	PTSRGGASVEETDQS CCCCCCCCCCCCCHH	33.08	20418363
570	Phosphorylation	TDQSHLATAGSTSSH CCHHCCCCCCCCCCC	37.60	27251275
573	Phosphorylation	SHLATAGSTSSHSLQ HCCCCCCCCCCCCEE	23.74	27251275
574	Phosphorylation	HLATAGSTSSHSLQK CCCCCCCCCCCCEEE	33.07	27251275
575	Phosphorylation	LATAGSTSSHSLQKY CCCCCCCCCCCEEEE	27.96	27251275
576	Phosphorylation	ATAGSTSSHSLQKYY CCCCCCCCCCEEEEE	19.72	27251275
578	Phosphorylation	AGSTSSHSLQKYYIT CCCCCCCCEEEEEEE	34.15	-
594	Phosphorylation	EAEGFPATV------ CCCCCCCCC------	27.30	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
52	Y	Phosphorylation	Kinase	ABL1	P00519	GPS
52	Y	Phosphorylation	Kinase	ABL-FAMILY	-	GPS
102	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
104	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
104	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
104	S	Phosphorylation	Kinase	CDK3	Q00526	PSP
104	S	Phosphorylation	Kinase	MAPK3	P27361	GPS
104	S	Phosphorylation	Kinase	MTOR	P42345	PSP
104	S	Phosphorylation	Kinase	CDK2	P24941	Uniprot
104	S	Phosphorylation	Kinase	CDK-FAMILY	-	GPS
104	S	Phosphorylation	Kinase	CDK_GROUP	-	PhosphoELM
106	S	Phosphorylation	Kinase	MTOR	P42345	PSP
106	S	Phosphorylation	Kinase	MAPK3	P27361	GPS
106	S	Phosphorylation	Kinase	CDK-FAMILY	-	GPS
106	S	Phosphorylation	Kinase	CDK_GROUP	-	PhosphoELM
106	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
106	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
106	S	Phosphorylation	Kinase	CDK3	Q00526	PSP
106	S	Phosphorylation	Kinase	CDK2	P24941	Uniprot
118	S	Phosphorylation	Kinase	MAPK-FAMILY	-	GPS
118	S	Phosphorylation	Kinase	MAPK_GROUP	-	PhosphoELM
118	S	Phosphorylation	Kinase	CDK3	Q00526	PSP
118	S	Phosphorylation	Kinase	MAPK14	Q16539	GPS
118	S	Phosphorylation	Kinase	RSK-SUBFAMILY	-	GPS
118	S	Phosphorylation	Kinase	RSK_GROUP	-	PhosphoELM
118	S	Phosphorylation	Kinase	CDK2	P24941	PSP
118	S	Phosphorylation	Kinase	CHUK	O15111	GPS
118	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
118	S	Phosphorylation	Kinase	CDK7	P50613	PSP
118	S	Phosphorylation	Kinase	MAPK3	P27361	GPS
118	S	Phosphorylation	Kinase	DDR1	Q08345	GPS
118	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
167	S	Phosphorylation	Kinase	CK2	-	Uniprot
167	S	Phosphorylation	Kinase	AKT-FAMILY	-	GPS
167	S	Phosphorylation	Kinase	RSK-SUBFAMILY	-	GPS
167	S	Phosphorylation	Kinase	CK2-FAMILY	-	GPS
167	S	Phosphorylation	Kinase	AKT2	P31751	PSP
167	S	Phosphorylation	Kinase	AURKA	O14965	GPS
167	S	Phosphorylation	Kinase	RSK_GROUP	-	PhosphoELM
167	S	Phosphorylation	Kinase	RPS6KB1	P23443	GPS
167	S	Phosphorylation	Kinase	RPS6KA3	P51812	GPS
167	S	Phosphorylation	Kinase	RPS6KA1	Q15418	GPS
167	S	Phosphorylation	Kinase	IKBKE	Q14164	GPS
167	S	Phosphorylation	Kinase	AKT1	P31749	PSP
167	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS
219	Y	Phosphorylation	Kinase	ABL1	P00519	GPS
219	Y	Phosphorylation	Kinase	IGF1R	P08069	PSP
219	Y	Phosphorylation	Kinase	ABL-FAMILY	-	GPS
236	S	Phosphorylation	Kinase	PRKACA	P17612	GPS
236	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
236	S	Phosphorylation	Kinase	PKA_GROUP	-	PhosphoELM
282	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS
294	S	Phosphorylation	Kinase	MAPK14	Q16539	GPS
294	S	Phosphorylation	Kinase	CDK2	P24941	PSP
305	S	Phosphorylation	Kinase	TBK1	Q9UHD2	PSP
305	S	Phosphorylation	Kinase	AURKA	O14965	GPS
305	S	Phosphorylation	Kinase	PAK4	O96013	PSP
305	S	Phosphorylation	Kinase	PAK1	Q13153	PSP
305	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
305	S	Phosphorylation	Kinase	AKT1	P31749	PSP
305	S	Phosphorylation	Kinase	PRKACA	P17612	GPS
311	T	Phosphorylation	Kinase	MAPK-FAMILY	-	GPS
311	T	Phosphorylation	Kinase	MAPK14	Q16539	GPS
311	T	Phosphorylation	Kinase	MAPK_GROUP	-	PhosphoELM
341	S	Phosphorylation	Kinase	CDK2	P24941	PSP
537	Y	Phosphorylation	Kinase	SRC64	-	PhosphoELM
537	Y	Phosphorylation	Kinase	CDKL2	Q92772	GPS
537	Y	Phosphorylation	Kinase	LCK	P06239	PSP
537	Y	Phosphorylation	Kinase	TYR-KINASES	-	Uniprot
537	Y	Phosphorylation	Kinase	SRC	P12931	PSP
559	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS
-	K	Ubiquitination	E3 ubiquitin ligase	SKP2	Q13309	PMID:23770852
-	K	Ubiquitination	E3 ubiquitin ligase	TRIM25	Q14258	PMID:16144914
-	K	Ubiquitination	E3 ubiquitin ligase	SPOP	O43791	PMID:25766326
-	K	Ubiquitination	E3 ubiquitin ligase	BARD1	Q99728	PMID:22199232
-	K	Ubiquitination	E3 ubiquitin ligase	STUB1	Q9UNE7	PMID:12239347
-	K	Ubiquitination	E3 ubiquitin ligase	BRCA1	P38398	PMID:17392432
-	K	Ubiquitination	E3 ubiquitin ligase	RBX1	P62877	PMID:20130088
-	K	Ubiquitination	E3 ubiquitin ligase	AHR	P35869	PMID:21397018
-	K	Ubiquitination	E3 ubiquitin ligase	UBE3A	Q05086	PMID:23542176

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
118	S	Phosphorylation	Dephosphorylation at Ser-118 by PPP5C inhibits its transactivation activity.	14764652
260	R	Methylation	Demethylated by JMJD6 at Arg-260.	18657504
260	R	Methylation	Dimethylated by PRMT1 at Arg-260.	18657504

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ESR1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TDIF2_HUMAN	DNTTIP2	physical	15047147
NELFB_HUMAN	NELFB	physical	15342491
XBP1_HUMAN	XBP1	physical	12954762
PHB2_HUMAN	PHB2	physical	12943695
TDG_HUMAN	TDG	physical	12874288
SAFB2_HUMAN	SAFB2	physical	12660241
MTA1_HUMAN	MTA1	physical	12167865
MAT1_HUMAN	MNAT1	physical	12527756
FKBP5_HUMAN	FKBP5	physical	9222609
FKBP4_HUMAN	FKBP4	physical	9222609
HS90A_HUMAN	HSP90AA1	physical	9222609
HSP74_HUMAN	HSPA4	physical	9222609
PPID_HUMAN	PPID	physical	9222609
TEBP_HUMAN	PTGES3	physical	9222609
MTA1_HUMAN	MTA1	physical	11146623
MPIP2_HUMAN	CDC25B	physical	11689696
MGMT_HUMAN	MGMT	physical	11564893
PELP1_HUMAN	PELP1	physical	11481323
TRIP4_HUMAN	TRIP4	physical	10454579
NCOA1_HUMAN	NCOA1	physical	11003650
SMCA4_HUMAN	SMARCA4	physical	11003650
NCOA1_HUMAN	NCOA1	physical	11113179
CBP_HUMAN	CREBBP	physical	11113179
PRDM2_HUMAN	PRDM2	physical	10706618
KDM5A_HUMAN	KDM5A	physical	11358960
CBP_HUMAN	CREBBP	physical	11782371
EP300_HUMAN	EP300	physical	11782371
BRCA1_HUMAN	BRCA1	physical	11782371
ESR1_HUMAN	ESR1	physical	12198596
NR2C2_HUMAN	NR2C2	physical	11844790
COT1_HUMAN	NR2F1	physical	12093745
MK01_HUMAN	MAPK1	physical	12093745
MDM2_HUMAN	MDM2	physical	10766163
NCOA2_HUMAN	NCOA2	physical	11937504
MVP_HUMAN	MVP	physical	9628887
HS90A_HUMAN	HSP90AA1	physical	11911945
ESR2_HUMAN	ESR2	physical	9473491
NRIP1_HUMAN	NRIP1	physical	7641693
CCND1_HUMAN	CCND1	physical	9039267
STAT3_HUMAN	STAT3	physical	11429412
NCOA1_HUMAN	NCOA1	physical	9427757
CEBPB_HUMAN	CEBPB	physical	7651415
SHC1_HUMAN	SHC1	physical	11773443
NGG1_YEAST	NGG1	physical	12034840
NCOA6_HUMAN	NCOA6	physical	11773444
CAV1_HUMAN	CAV1	physical	11563984
NRIP1_HUMAN	NRIP1	physical	8887632
NCOA3_HUMAN	NCOA3	physical	11050174
FOXO1_HUMAN	FOXO1	physical	11435445
FOXO4_HUMAN	FOXO4	physical	11435445
P85A_HUMAN	PIK3R1	physical	11689445
BAG1_HUMAN	BAG1	physical	8524784
NR0B2_HUMAN	NR0B2	physical	11861507
ANM2_HUMAN	PRMT2	physical	12039952
SMAD2_HUMAN	SMAD2	physical	11555647
NR0B2_RAT	Nr0b2	physical	10648597
MED12_HUMAN	MED12	physical	11867769
MED1_HUMAN	MED1	physical	11867769
MED14_HUMAN	MED14	physical	11867769
MED23_HUMAN	MED23	physical	11867769
MED24_HUMAN	MED24	physical	11867769
MED16_HUMAN	MED16	physical	11867769
MED6_HUMAN	MED6	physical	11867769
MED20_HUMAN	MED20	physical	11867769
MED10_HUMAN	MED10	physical	11867769
MED17_HUMAN	MED17	physical	11867769
MED7_HUMAN	MED7	physical	11867769
MED21_HUMAN	MED21	physical	11867769
EP300_HUMAN	EP300	physical	11867769
MED13_HUMAN	MED13	physical	11867769
NCOA1_HUMAN	NCOA1	physical	11867769
CCNC_HUMAN	CCNC	physical	11867769
CDK8_HUMAN	CDK8	physical	11867769
RNF12_HUMAN	RLIM	physical	19117995
PDLI1_HUMAN	PDLIM1	physical	19117995
ESR1_HUMAN	ESR1	physical	19117995
SRC_HUMAN	SRC	physical	11013076
ESR2_HUMAN	ESR2	physical	10706629
NCOA2_HUMAN	NCOA2	physical	12612084
TRAM1_HUMAN	TRAM1	physical	12612084
NCOA2_HUMAN	NCOA2	physical	18499756
MUC1_HUMAN	MUC1	physical	16427018
UBE3A_HUMAN	UBE3A	physical	16314411
CHIP_HUMAN	STUB1	physical	16037132
HSP7C_HUMAN	HSPA8	physical	16037132
HS90A_HUMAN	HSP90AA1	physical	16037132
HDAC7_HUMAN	HDAC7	physical	19917725
HDAC4_HUMAN	HDAC4	physical	19893013
HDAC5_HUMAN	HDAC5	physical	19893013
HDAC9_HUMAN	HDAC9	physical	19893013
FLII_HUMAN	FLII	physical	19720835
KLF5_HUMAN	KLF5	physical	19569049
SMYD3_HUMAN	SMYD3	physical	19509295
HSP7C_HUMAN	HSPA8	physical	15538384
CHIP_HUMAN	STUB1	physical	15538384
BAG1_HUMAN	BAG1	physical	15538384
HS90A_HUMAN	HSP90AA1	physical	15538384
HSP74_HUMAN	HSPA4	physical	15538384
MYOD1_HUMAN	MYOD1	physical	18765668
SP1_HUMAN	SP1	physical	18765668
CBP_HUMAN	CREBBP	physical	18765668
EP300_HUMAN	EP300	physical	18765668
BRCA1_HUMAN	BRCA1	physical	16860316
NCOA6_HUMAN	NCOA6	physical	16794079
TOP2B_HUMAN	TOP2B	physical	16794079
PRKDC_HUMAN	PRKDC	physical	16794079
PARP1_HUMAN	PARP1	physical	16794079
XRCC5_HUMAN	XRCC5	physical	16794079
XRCC6_HUMAN	XRCC6	physical	16794079
MEN1_HUMAN	MEN1	physical	16651450
SP1_HUMAN	SP1	physical	16651265
SP3_HUMAN	SP3	physical	16651265
CEBPB_HUMAN	CEBPB	physical	16651265
MTA2_HUMAN	MTA2	physical	16645043
NCOA2_HUMAN	NCOA2	physical	16645043
NCOA3_HUMAN	NCOA3	physical	18645020
TF65_HUMAN	RELA	physical	16497877
MYC_HUMAN	MYC	physical	16455494
NRIP1_HUMAN	NRIP1	physical	16439465
RBBP7_HUMAN	RBBP7	physical	18577416
RBBP4_HUMAN	RBBP4	physical	18577416
LMO4_HUMAN	LMO4	physical	16288053
EP300_HUMAN	EP300	physical	12714702
NCOA3_HUMAN	NCOA3	physical	12714702
NCOA2_HUMAN	NCOA2	physical	12714702
NCOA1_HUMAN	NCOA1	physical	12714702
TAF1A_HUMAN	TAF1A	physical	12511607
TAF1B_HUMAN	TAF1B	physical	12511607
BRCA1_HUMAN	BRCA1	physical	16061635
CCND1_HUMAN	CCND1	physical	16061635
HDAC4_HUMAN	HDAC4	physical	16051668
SP1_HUMAN	SP1	physical	15987735
SP2_HUMAN	SP2	physical	15987735
MSH2_HUMAN	MSH2	physical	15886699
MED1_HUMAN	MED1	physical	15886699
CDN1A_HUMAN	CDKN1A	physical	15743834
IRS1_HUMAN	IRS1	physical	12821935
IRS2_HUMAN	IRS2	physical	12821935
NCOA2_HUMAN	NCOA2	physical	15657427
CITE1_HUMAN	CITED1	physical	11581164
HDAC1_HUMAN	HDAC1	physical	15557281
SP1_HUMAN	SP1	physical	15557281
PRDM2_HUMAN	PRDM2	physical	15282304
MED14_HUMAN	MED14	physical	10770935
MED1_HUMAN	MED1	physical	10770935
NCOA1_HUMAN	NCOA1	physical	10760302
MED1_HUMAN	MED1	physical	10760302
PHB2_HUMAN	PHB2	physical	15140878
HDAC1_HUMAN	HDAC1	physical	15140878
NCOA1_HUMAN	NCOA1	physical	9773983
GRIP1_HUMAN	GRIP1	physical	9773983
NCOA7_HUMAN	NCOA7	physical	9259327
TIF1A_HUMAN	TRIM24	physical	9259327
NCOA1_HUMAN	NCOA1	physical	9259327
TBP_HUMAN	TBP	physical	9259327
TF2B_HUMAN	GTF2B	physical	9259327
NCOA1_HUMAN	NCOA1	physical	9192902
NCOA3_HUMAN	NCOA3	physical	9192892
NCOA1_HUMAN	NCOA1	physical	9192892
NCOA2_HUMAN	NCOA2	physical	9192892
NCOR2_HUMAN	NCOR2	physical	9171229
TF65_HUMAN	RELA	physical	17932106
NCOR1_HUMAN	NCOR1	physical	17400812
SRC_HUMAN	SRC	physical	17400812
CBP_HUMAN	CREBBP	physical	17400812
PRGC2_HUMAN	PPARGC1B	physical	17631495
KDM1A_HUMAN	KDM1A	physical	17289570
NCOA3_HUMAN	NCOA3	physical	20392877
NCOR2_HUMAN	NCOR2	physical	20392877
ESR1_HUMAN	ESR1	physical	20353944
HS90A_HUMAN	HSP90AA1	physical	20353944
GELS_HUMAN	GSN	physical	20308691
ACTB_HUMAN	ACTB	physical	20308691
NPM_HUMAN	NPM1	physical	20308691
ACTC_HUMAN	ACTC1	physical	20308691
HSP7C_HUMAN	HSPA8	physical	20308691
RL18_HUMAN	RPL18	physical	20308691
DDX5_HUMAN	DDX5	physical	20308691
RLA0_HUMAN	RPLP0	physical	20308691
RL7A_HUMAN	RPL7A	physical	20308691
MYL6_HUMAN	MYL6	physical	20308691
RL7_HUMAN	RPL7	physical	20308691
RS4X_HUMAN	RPS4X	physical	20308691
MYO1C_HUMAN	MYO1C	physical	20308691
DDX3X_HUMAN	DDX3X	physical	20308691
RS9_HUMAN	RPS9	physical	20308691
RS8_HUMAN	RPS8	physical	20308691
ARP3_HUMAN	ACTR3	physical	20308691
ARP2_HUMAN	ACTR2	physical	20308691
RPB1_HUMAN	POLR2A	physical	20308691
MBD2_HUMAN	MBD2	physical	20300195
RBBP6_HUMAN	RBBP6	physical	20184719
PRDM2_HUMAN	PRDM2	physical	19746436
ESR2_HUMAN	ESR2	physical	19746436
SMAD2_HUMAN	SMAD2	physical	20207742
SMUF1_HUMAN	SMURF1	physical	20207742
HSP74_HUMAN	HSPA4	physical	21503962
HS90A_HUMAN	HSP90AA1	physical	21503962
SGK3_HUMAN	SGK3	physical	21084382
BRCA1_HUMAN	BRCA1	physical	20060929
BARD1_HUMAN	BARD1	physical	20060929
OTUB1_HUMAN	OTUB1	physical	19383985
DUT_HUMAN	DUT	physical	15604093
ANF_HUMAN	NPPA	physical	15604093
MTCH2_HUMAN	MTCH2	physical	15604093
PNRC2_HUMAN	PNRC2	physical	15604093
KIF1A_HUMAN	KIF1A	physical	15604093
KMT2D_HUMAN	KMT2D	physical	16603732
RBBP5_HUMAN	RBBP5	physical	16603732
ASH2L_HUMAN	ASH2L	physical	16603732
WDR5_HUMAN	WDR5	physical	16603732
TBB1_HUMAN	TUBB1	physical	15556606
HSP74_HUMAN	HSPA4	physical	15556606
TBA1A_HUMAN	TUBA1A	physical	15556606
BRCA1_HUMAN	BRCA1	physical	19887647
EP300_HUMAN	EP300	physical	19887647
CDN1A_HUMAN	CDKN1A	physical	17911387
PRS8_HUMAN	PSMC5	physical	8598193
TIF1A_HUMAN	TRIM24	physical	8598193
NCOA3_HUMAN	NCOA3	physical	9346901
AKT2_HUMAN	AKT2	physical	11507039
FOXO1_HUMAN	FOXO1	physical	11353774
NCOA3_HUMAN	NCOA3	physical	11353774
DDX17_HUMAN	DDX17	physical	12738788
EP300_HUMAN	EP300	physical	12738788
DDX5_HUMAN	DDX5	physical	12738788
NCOA1_HUMAN	NCOA1	physical	12738788
MED1_HUMAN	MED1	physical	12738788
TRRAP_HUMAN	TRRAP	physical	12738788
NCOR1_HUMAN	NCOR1	physical	12738788
NCOR2_HUMAN	NCOR2	physical	12738788
3MG_HUMAN	MPG	physical	14761960
BCAR1_HUMAN	BCAR1	physical	15020686
SRC_HUMAN	SRC	physical	15020686
P85B_HUMAN	PIK3R2	physical	15020686
ERBB2_HUMAN	ERBB2	physical	15173068
SOS2_HUMAN	SOS2	physical	15173068
NCOA3_HUMAN	NCOA3	physical	15383283
FHL2_HUMAN	FHL2	physical	15666801
UBC9_HUMAN	UBE2I	physical	15666801
PIAS1_HUMAN	PIAS1	physical	15666801
CUED2_HUMAN	CUEDC2	physical	21572428
KMT2D_HUMAN	KMT2D	physical	21502505
WDR5_HUMAN	WDR5	physical	21502505
RBBP5_HUMAN	RBBP5	physical	21502505
ASH2L_HUMAN	ASH2L	physical	21502505
KDM4B_HUMAN	KDM4B	physical	21502505
GDIR1_HUMAN	ARHGDIA	physical	21447808
NCOA3_HUMAN	NCOA3	physical	19491275
NCOA3_HUMAN	NCOA3	physical	18484708
KPCZ_HUMAN	PRKCZ	physical	18313384
TFF1_HUMAN	TFF1	genetic	18313384
NCOA3_HUMAN	NCOA3	physical	17646391
NCOA3_HUMAN	NCOA3	physical	15145444
MTA1_HUMAN	MTA1	physical	12639951
BL1S1_HUMAN	BLOC1S1	physical	12639951
ESR2_HUMAN	ESR2	physical	12630920
SRC_HUMAN	SRC	physical	12630920
NCOA2_HUMAN	NCOA2	physical	12630920
NCOA1_HUMAN	NCOA1	physical	12630920
NCOA3_HUMAN	NCOA3	physical	12630920
ESR1_HUMAN	ESR1	physical	12554772
NCOA1_HUMAN	NCOA1	physical	12554772
NCOA2_HUMAN	NCOA2	physical	12554772
NCOA3_HUMAN	NCOA3	physical	12554772
NCOA1_HUMAN	NCOA1	physical	11376110
NCOA2_HUMAN	NCOA2	physical	11376110
NCOA3_HUMAN	NCOA3	physical	11376110
NCOA1_HUMAN	NCOA1	physical	11014206
NCOA2_HUMAN	NCOA2	physical	11014206
TRAM1_HUMAN	TRAM1	physical	11014206
EHMT2_HUMAN	EHMT2	physical	21984853
NCOA3_HUMAN	NCOA3	physical	9765300
TAF2_HUMAN	TAF2	physical	9765300
PRGR_HUMAN	PGR	physical	22396492
FOXO1_HUMAN	FOXO1	physical	22266855
E2F1_HUMAN	E2F1	physical	22216287
KAT5_HUMAN	KAT5	physical	22081016
TAB2_HUMAN	TAB2	physical	22249258
MDM2_HUMAN	MDM2	physical	12897156
CDN1A_HUMAN	CDKN1A	physical	12897156
UIMC1_HUMAN	UIMC1	physical	17311814
HAKAI_HUMAN	CBLL1	physical	20608937
NCOA1_HUMAN	NCOA1	physical	20608937
HS90A_HUMAN	HSP90AA1	physical	18388150
CHIP_HUMAN	STUB1	physical	18388150
BAG1_HUMAN	BAG1	physical	18388150
TEBP_HUMAN	PTGES3	physical	18388150
MDM2_HUMAN	MDM2	physical	17545634
P53_HUMAN	TP53	physical	17545634
CD11B_HUMAN	CDK11B	physical	19122208
SPOP_HUMAN	SPOP	physical	18414007
CUL3_HUMAN	CUL3	physical	18414007
BRCA1_HUMAN	BRCA1	physical	11244506
NCOA1_HUMAN	NCOA1	physical	9774463
NCOA2_HUMAN	NCOA2	physical	9774463
TIF1A_HUMAN	TRIM24	physical	9774463
BRCA1_HUMAN	BRCA1	physical	15674350
ARI5A_HUMAN	ARID5A	physical	15941852
BRCA1_HUMAN	BRCA1	physical	17505062
MDM2_HUMAN	MDM2	physical	11178989
BCAR1_HUMAN	BCAR1	physical	19331827
TRAF6_HUMAN	TRAF6	physical	19331827
BRCA1_HUMAN	BRCA1	physical	12400015
HOIL1_HUMAN	RBCK1	physical	23042805
TAB2_HUMAN	TAB2	physical	16469706
NCOR1_HUMAN	NCOR1	physical	16469706
HDAC3_HUMAN	HDAC3	physical	16469706
TBL1R_HUMAN	TBL1XR1	physical	16469706
SIN3A_HUMAN	SIN3A	physical	16469706
SIN3B_HUMAN	SIN3B	physical	16469706
PELP1_HUMAN	PELP1	physical	14963108
AN32A_HUMAN	ANP32A	physical	15308690
TF65_HUMAN	RELA	physical	16331275
BCL3_HUMAN	BCL3	physical	16331275
TSC2_HUMAN	TSC2	physical	15039427
EGFR_HUMAN	EGFR	physical	17284441
ACTB_HUMAN	ACTB	physical	21182205
MYLK2_HUMAN	MYLK2	physical	21182205
ARGI1_HUMAN	ARG1	physical	21182205
DSG1_HUMAN	DSG1	physical	21182205
HIF1A_HUMAN	HIF1A	physical	21182205
DDX5_HUMAN	DDX5	physical	21182205
NPM_HUMAN	NPM1	physical	21182205
CLH2_HUMAN	CLTCL1	physical	21182205
HPCL1_HUMAN	HPCAL1	physical	21182205
APOD_HUMAN	APOD	physical	21182205
SERPH_HUMAN	SERPINH1	physical	21182205
BUD13_HUMAN	BUD13	physical	21182205
ESR1_HUMAN	ESR1	physical	21182205
ACTC_HUMAN	ACTC1	physical	21182205
AKAP8_HUMAN	AKAP8	physical	21182205
ATD3A_HUMAN	ATAD3A	physical	21182205
BCLF1_HUMAN	BCLAF1	physical	21182205
EMSA1_HUMAN	ELMSAN1	physical	21182205
CAPR1_HUMAN	CAPRIN1	physical	21182205
CLH1_HUMAN	CLTC	physical	21182205
DDX17_HUMAN	DDX17	physical	21182205
DDX18_HUMAN	DDX18	physical	21182205
DDX21_HUMAN	DDX21	physical	21182205
DDX27_HUMAN	DDX27	physical	21182205
DDX3X_HUMAN	DDX3X	physical	21182205
DDX54_HUMAN	DDX54	physical	21182205
DHX15_HUMAN	DHX15	physical	21182205
DHX9_HUMAN	DHX9	physical	21182205
DKC1_HUMAN	DKC1	physical	21182205
EWS_HUMAN	EWSR1	physical	21182205
FLNA_HUMAN	FLNA	physical	21182205
SPB1_HUMAN	FTSJ3	physical	21182205
FUS_HUMAN	FUS	physical	21182205
GNL3_HUMAN	GNL3	physical	21182205
GELS_HUMAN	GSN	physical	21182205
NOG1_HUMAN	GTPBP4	physical	21182205
HDAC1_HUMAN	HDAC1	physical	21182205
HDAC2_HUMAN	HDAC2	physical	21182205
ROA3_HUMAN	HNRNPA3	physical	21182205
HNRPF_HUMAN	HNRNPF	physical	21182205
HNRPK_HUMAN	HNRNPK	physical	21182205
HNRPM_HUMAN	HNRNPM	physical	21182205
HNRPR_HUMAN	HNRNPR	physical	21182205
ROA1_HUMAN	HNRNPA1	physical	21182205
RA1L2_HUMAN	HNRNPA1L2	physical	21182205
HSP7C_HUMAN	HSPA8	physical	21182205
ILF2_HUMAN	ILF2	physical	21182205
PLAK_HUMAN	JUP	physical	21182205
KI67_HUMAN	MKI67	physical	21182205
MBB1A_HUMAN	MYBBP1A	physical	21182205
MYH9_HUMAN	MYH9	physical	21182205
MYL6_HUMAN	MYL6	physical	21182205
MYO1B_HUMAN	MYO1B	physical	21182205
MYO1C_HUMAN	MYO1C	physical	21182205
NAT10_HUMAN	NAT10	physical	21182205
NUCL_HUMAN	NCL	physical	21182205
NOP56_HUMAN	NOP56	physical	21182205
NUMA1_HUMAN	NUMA1	physical	21182205
PABP1_HUMAN	PABPC1	physical	21182205
PELP1_HUMAN	PELP1	physical	21182205
PGAM5_HUMAN	PGAM5	physical	21182205
HACD3_HUMAN	PTPLAD1	physical	21182205
RBM14_HUMAN	RBM14	physical	21182205
RBM39_HUMAN	RBM39	physical	21182205
RBMX_HUMAN	RBMX	physical	21182205
RL10_HUMAN	RPL10	physical	21182205
RL13_HUMAN	RPL13	physical	21182205
RL13A_HUMAN	RPL13A	physical	21182205
RL14_HUMAN	RPL14	physical	21182205
RL17_HUMAN	RPL17	physical	21182205
RL18_HUMAN	RPL18	physical	21182205
RL18A_HUMAN	RPL18A	physical	21182205
RL19_HUMAN	RPL19	physical	21182205
RL22_HUMAN	RPL22	physical	21182205
RL24_HUMAN	RPL24	physical	21182205
RL27A_HUMAN	RPL27A	physical	21182205
RL3_HUMAN	RPL3	physical	21182205
RL36L_HUMAN	RPL36AL	physical	21182205
RL36A_HUMAN	RPL36A	physical	21182205
RL37A_HUMAN	RPL37A	physical	21182205
RL4_HUMAN	RPL4	physical	21182205
RL6_HUMAN	RPL6	physical	21182205
RL7_HUMAN	RPL7	physical	21182205
RL7A_HUMAN	RPL7A	physical	21182205
RL8_HUMAN	RPL8	physical	21182205
RLA0_HUMAN	RPLP0	physical	21182205
RPN1_HUMAN	RPN1	physical	21182205
RPN2_HUMAN	RPN2	physical	21182205
RS14_HUMAN	RPS14	physical	21182205
RS16_HUMAN	RPS16	physical	21182205
RS2_HUMAN	RPS2	physical	21182205
RS23_HUMAN	RPS23	physical	21182205
RS26_HUMAN	RPS26	physical	21182205
RS3A_HUMAN	RPS3A	physical	21182205
RS4X_HUMAN	RPS4X	physical	21182205
RS6_HUMAN	RPS6	physical	21182205
RS8_HUMAN	RPS8	physical	21182205
RS9_HUMAN	RPS9	physical	21182205
RRP12_HUMAN	RRP12	physical	21182205
RL1D1_HUMAN	RSL1D1	physical	21182205
SRSF1_HUMAN	SRSF1	physical	21182205
SRSF2_HUMAN	SRSF2	physical	21182205
SRSF7_HUMAN	SRSF7	physical	21182205
ADT2_HUMAN	SLC25A5	physical	21182205
SRRM1_HUMAN	SRRM1	physical	21182205
TRFE_HUMAN	TF	physical	21182205
TFR1_HUMAN	TFRC	physical	21182205
TR150_HUMAN	THRAP3	physical	21182205
TOP1_HUMAN	TOP1	physical	21182205
TOP2A_HUMAN	TOP2A	physical	21182205
TOP2B_HUMAN	TOP2B	physical	21182205
TRIPC_HUMAN	TRIP12	physical	21182205
UBF1_HUMAN	UBTF	physical	21182205
U2AF2_HUMAN	U2AF2	physical	21182205
ACTN1_HUMAN	ACTN1	physical	21182205
ARP2_HUMAN	ACTR2	physical	21182205
ARP3_HUMAN	ACTR3	physical	21182205
AHNK_HUMAN	AHNAK	physical	21182205
AIFM1_HUMAN	AIFM1	physical	21182205
ALKB7_HUMAN	ALKBH7	physical	21182205
AP2M1_HUMAN	AP2M1	physical	21182205
ARFG2_HUMAN	ARFGAP2	physical	21182205
ARSB_HUMAN	ARSB	physical	21182205
ATPB_HUMAN	ATP5B	physical	21182205
ATP9A_HUMAN	ATP9A	physical	21182205
BRI3B_HUMAN	BRI3BP	physical	21182205
CAPZB_HUMAN	CAPZB	physical	21182205
CHD4_HUMAN	CHD4	physical	21182205
LC7L3_HUMAN	LUC7L3	physical	21182205
YBOX3_HUMAN	YBX3	physical	21182205
DREB_HUMAN	DBN1	physical	21182205
DDX50_HUMAN	DDX50	physical	21182205
DECR_HUMAN	DECR1	physical	21182205
DEK_HUMAN	DEK	physical	21182205
DHX30_HUMAN	DHX30	physical	21182205
DYH2_HUMAN	DNAH2	physical	21182205
DJB11_HUMAN	DNAJB11	physical	21182205
U5S1_HUMAN	EFTUD2	physical	21182205
IF4A1_HUMAN	EIF4A1	physical	21182205
IF4G1_HUMAN	EIF4G1	physical	21182205
IF4G3_HUMAN	EIF4G3	physical	21182205
EP400_HUMAN	EP400	physical	21182205
E41L5_HUMAN	EPB41L5	physical	21182205
FLNB_HUMAN	FLNB	physical	21182205
FMR1_HUMAN	FMR1	physical	21182205
G3BP1_HUMAN	G3BP1	physical	21182205
G3BP2_HUMAN	G3BP2	physical	21182205
GBB1_HUMAN	GNB1	physical	21182205
GBB2_HUMAN	GNB2	physical	21182205
GBB4_HUMAN	GNB4	physical	21182205
NOG2_HUMAN	GNL2	physical	21182205
GOGA2_HUMAN	GOLGA2	physical	21182205
ROA0_HUMAN	HNRNPA0	physical	21182205
ROA2_HUMAN	HNRNPA2B1	physical	21182205
ROAA_HUMAN	HNRNPAB	physical	21182205
LYAR_HUMAN	LYAR	physical	21182205
RT09_HUMAN	MRPS9	physical	21182205
LYRIC_HUMAN	MTDH	physical	21182205
MYH14_HUMAN	MYH14	physical	21182205
MYO6_HUMAN	MYO6	physical	21182205
NOP2_HUMAN	NOP2	physical	21182205
NOP58_HUMAN	NOP58	physical	21182205
GLYR1_HUMAN	GLYR1	physical	21182205
NU153_HUMAN	NUP153	physical	21182205
PARP1_HUMAN	PARP1	physical	21182205
POP1_HUMAN	POP1	physical	21182205
PP1A_HUMAN	PPP1CA	physical	21182205
PRKDC_HUMAN	PRKDC	physical	21182205
PRP4B_HUMAN	PRPF4B	physical	21182205
PSIP1_HUMAN	PSIP1	physical	21182205
RBBP4_HUMAN	RBBP4	physical	21182205
RBBP7_HUMAN	RBBP7	physical	21182205
RBM28_HUMAN	RBM28	physical	21182205
RL10A_HUMAN	RPL10A	physical	21182205
RL11_HUMAN	RPL11	physical	21182205
RL23A_HUMAN	RPL23A	physical	21182205
RL36_HUMAN	RPL36	physical	21182205
RL5_HUMAN	RPL5	physical	21182205
RL9_HUMAN	RPL9	physical	21182205
RS12_HUMAN	RPS12	physical	21182205
RS13_HUMAN	RPS13	physical	21182205
RS15A_HUMAN	RPS15A	physical	21182205
RS20_HUMAN	RPS20	physical	21182205
RS24_HUMAN	RPS24	physical	21182205
RS3_HUMAN	RPS3	physical	21182205
RSSA_HUMAN	RPSA	physical	21182205
RUVB1_HUMAN	RUVBL1	physical	21182205
RUVB2_HUMAN	RUVBL2	physical	21182205
SCYL2_HUMAN	SCYL2	physical	21182205
SRSF6_HUMAN	SRSF6	physical	21182205
SHOC2_HUMAN	SHOC2	physical	21182205
SMD1_HUMAN	SNRPD1	physical	21182205
SPTN1_HUMAN	SPTAN1	physical	21182205
SPTB2_HUMAN	SPTBN1	physical	21182205
SRPK1_HUMAN	SRPK1	physical	21182205
SRPK2_HUMAN	SRPK2	physical	21182205
SRRM2_HUMAN	SRRM2	physical	21182205
STAU1_HUMAN	STAU1	physical	21182205
SP16H_HUMAN	SUPT16H	physical	21182205
TBL2_HUMAN	TBL2	physical	21182205
TCOF_HUMAN	TCOF1	physical	21182205
UBP2L_HUMAN	UBAP2L	physical	21182205
UN45A_HUMAN	UNC45A	physical	21182205
RENT1_HUMAN	UPF1	physical	21182205
SAS10_HUMAN	UTP3	physical	21182205
WDR36_HUMAN	WDR36	physical	21182205
YBOX1_HUMAN	YBX1	physical	21182205
YTHD2_HUMAN	YTHDF2	physical	21182205
ANXA2_HUMAN	ANXA2	physical	21182205
DDX3Y_HUMAN	DDX3Y	physical	21182205
THEM6_HUMAN	THEM6	physical	21182205
EMD_HUMAN	EMD	physical	21182205
EPIPL_HUMAN	EPPK1	physical	21182205
EXOSX_HUMAN	EXOSC10	physical	21182205
H2AX_HUMAN	H2AFX	physical	21182205
HS71L_HUMAN	HSPA1L	physical	21182205
HNRPQ_HUMAN	SYNCRIP	physical	21182205
G3P_HUMAN	GAPDH	physical	21182205
TECR_HUMAN	TECR	physical	21182205
KHDR1_HUMAN	KHDRBS1	physical	21182205
LEG7_HUMAN	LGALS7	physical	21182205
MAPK2_HUMAN	MAPKAPK2	physical	21182205
MYL6B_HUMAN	MYL6B	physical	21182205
FBX50_HUMAN	NCCRP1	physical	21182205
POF1B_HUMAN	POF1B	physical	21182205
PLEC_HUMAN	PLEC	physical	21182205
RL29_HUMAN	RPL29	physical	21182205
RRP1B_HUMAN	RRP1B	physical	21182205
RL12_HUMAN	RPL12	physical	21182205
RL28_HUMAN	RPL28	physical	21182205
RL21_HUMAN	RPL21	physical	21182205
RS18_HUMAN	RPS18	physical	21182205
RADI_HUMAN	RDX	physical	21182205
SRSF5_HUMAN	SRSF5	physical	21182205
S10A7_HUMAN	S100A7	physical	21182205
SPB4_HUMAN	SERPINB4	physical	21182205
1433S_HUMAN	SFN	physical	21182205
SC61B_HUMAN	SEC61B	physical	21182205
SF3B1_HUMAN	SF3B1	physical	21182205
SRSF3_HUMAN	SRSF3	physical	21182205
S10A8_HUMAN	S100A8	physical	21182205
SR140_HUMAN	U2SURP	physical	21182205
WDR18_HUMAN	WDR18	physical	21182205
VP13D_HUMAN	VPS13D	physical	21182205
Z512B_HUMAN	ZNF512B	physical	21182205
NCOA2_HUMAN	NCOA2	physical	9430642
SRA1_HUMAN	SRA1	physical	20398657
BTF3_HUMAN	BTF3	physical	18025262
SRC_HUMAN	SRC	physical	17627277
PPP5_HUMAN	PPP5C	physical	14764652
CCNT1_HUMAN	CCNT1	physical	15940264
HEXI1_HUMAN	HEXIM1	physical	15940264
MCAT_HUMAN	SLC25A20	physical	23178685
EZH2_HUMAN	EZH2	physical	17502350
STA5A_HUMAN	STAT5A	physical	15304355
TSC1_HUMAN	TSC1	physical	15851513
TSC2_HUMAN	TSC2	physical	15851513
PAGR1_HUMAN	PAGR1	physical	19039327
PAK1_HUMAN	PAK1	physical	12374744
CHD9_HUMAN	CHD9	physical	16554032
SPF27_HUMAN	BCAS2	physical	15694360
P85A_HUMAN	PIK3R1	physical	11029009
PK3CA_HUMAN	PIK3CA	physical	11029009
HS90A_HUMAN	HSP90AA1	physical	23912458
HOIL1_HUMAN	RBCK1	physical	23912458
FKBPL_HUMAN	FKBPL	physical	23912458
ZDH21_HUMAN	ZDHHC21	physical	22031296
ZDHC7_HUMAN	ZDHHC7	physical	22031296
K2C1_HUMAN	KRT1	physical	23576398
CE290_HUMAN	CEP290	physical	23576398
ESR1_HUMAN	ESR1	physical	23576398
HSPB1_HUMAN	HSPB1	physical	23576398
PRDX2_HUMAN	PRDX2	physical	23576398
NDKB_HUMAN	NME2	physical	23576398
PPIA_HUMAN	PPIA	physical	23576398
PROF1_HUMAN	PFN1	physical	23576398
CBR1_HUMAN	CBR1	physical	23576398
GSTM3_HUMAN	GSTM3	physical	23576398
RNF31_HUMAN	RNF31	physical	24441041
NCOA1_HUMAN	NCOA1	physical	23975195
ESR1_HUMAN	ESR1	physical	23159625
ZN131_HUMAN	ZNF131	physical	23159625
SRC_HUMAN	SRC	physical	24051437
HDAC1_HUMAN	HDAC1	physical	24051437
PHB2_HUMAN	PHB2	physical	24051437
NCOR1_HUMAN	NCOR1	physical	24051437
PK3CA_HUMAN	PIK3CA	physical	24051437
SRC_HUMAN	SRC	physical	16957778
PSB9_HUMAN	PSMB9	physical	16957778
RPB1_HUMAN	POLR2A	physical	16957778
RPB2_HUMAN	POLR2B	physical	16957778
RPB3_HUMAN	POLR2C	physical	16957778
RPB4_HUMAN	POLR2D	physical	16957778
RPAB1_HUMAN	POLR2E	physical	16957778
RPAB2_HUMAN	POLR2F	physical	16957778
RPB7_HUMAN	POLR2G	physical	16957778
RPAB3_HUMAN	POLR2H	physical	16957778
RPB9_HUMAN	POLR2I	physical	16957778
RPAB5_HUMAN	POLR2L	physical	16957778
RPB11_HUMAN	POLR2J	physical	16957778
RPAB4_HUMAN	POLR2K	physical	16957778
ASCC1_HUMAN	ASCC1	physical	25219498
SKP2_HUMAN	SKP2	physical	23770852
EP300_HUMAN	EP300	physical	20348541
NCOA2_HUMAN	NCOA2	physical	20348541
RPB1_HUMAN	POLR2A	physical	20348541
HDAC3_HUMAN	HDAC3	physical	20348541
AN32B_HUMAN	ANP32B	physical	20348541
SND1_HUMAN	SND1	physical	20348541
SFPQ_HUMAN	SFPQ	physical	20348541
HSP74_HUMAN	HSPA4	physical	20348541
PQBP1_HUMAN	PQBP1	physical	20348541
THOC4_HUMAN	ALYREF	physical	20348541
RACK1_HUMAN	GNB2L1	physical	20348541
HNRPQ_HUMAN	SYNCRIP	physical	20348541
MBB1A_HUMAN	MYBBP1A	physical	20348541
DDX17_HUMAN	DDX17	physical	20348541
TCPB_HUMAN	CCT2	physical	20348541
TCRG1_HUMAN	TCERG1	physical	20348541
CPSF5_HUMAN	NUDT21	physical	20348541
TOPB1_HUMAN	TOPBP1	physical	20348541
CIRBP_HUMAN	CIRBP	physical	20348541
SYDC_HUMAN	DARS	physical	20348541
DREB_HUMAN	DBN1	physical	20348541
DDX1_HUMAN	DDX1	physical	20348541
DDX3X_HUMAN	DDX3X	physical	20348541
DHX9_HUMAN	DHX9	physical	20348541
EF2_HUMAN	EEF2	physical	20348541
IF4A1_HUMAN	EIF4A1	physical	20348541
IF5A1_HUMAN	EIF5A	physical	20348541
TBB5_HUMAN	TUBB	physical	20348541
SYEP_HUMAN	EPRS	physical	20348541
ESR1_HUMAN	ESR1	physical	20348541
SYFA_HUMAN	FARSA	physical	20348541
SEPT8_HUMAN	SEPT8	physical	20348541
PAIRB_HUMAN	SERBP1	physical	20348541
PRP19_HUMAN	PRPF19	physical	20348541
PDIA3_HUMAN	PDIA3	physical	20348541
H2B1D_HUMAN	HIST1H2BD	physical	20348541
H2B1C_HUMAN	HIST1H2BD	physical	20348541
H33_HUMAN	H3F3A	physical	20348541
VIGLN_HUMAN	HDLBP	physical	20348541
ROA1_HUMAN	HNRNPA1	physical	20348541
ROA2_HUMAN	HNRNPA2B1	physical	20348541
HNRPC_HUMAN	HNRNPC	physical	20348541
HNRPD_HUMAN	HNRNPD	physical	20348541
HSPB1_HUMAN	HSPB1	physical	20348541
ILF3_HUMAN	ILF3	physical	20348541
SYK_HUMAN	KARS	physical	20348541
K2C8_HUMAN	KRT8	physical	20348541
K1C10_HUMAN	KRT10	physical	20348541
K1C18_HUMAN	KRT18	physical	20348541
K1C19_HUMAN	KRT19	physical	20348541
SYMC_HUMAN	MARS	physical	20348541
C1TC_HUMAN	MTHFD1	physical	20348541
NP1L4_HUMAN	NAP1L4	physical	20348541
NUCL_HUMAN	NCL	physical	20348541
SEPT2_HUMAN	SEPT2	physical	20348541
NONO_HUMAN	NONO	physical	20348541
NPM_HUMAN	NPM1	physical	20348541
NSF_HUMAN	NSF	physical	20348541
PDIA1_HUMAN	P4HB	physical	20348541
PA2G4_HUMAN	PA2G4	physical	20348541
RTCB_HUMAN	RTCB	physical	20348541
SYLC_HUMAN	LARS	physical	20348541
PPIB_HUMAN	PPIB	physical	20348541
SYSM_HUMAN	SARS2	physical	20348541
PP1A_HUMAN	PPP1CA	physical	20348541
2AAA_HUMAN	PPP2R1A	physical	20348541
PSPC1_HUMAN	PSPC1	physical	20348541
GLU2B_HUMAN	PRKCSH	physical	20348541
PSMD1_HUMAN	PSMD1	physical	20348541
SNX6_HUMAN	SNX6	physical	20348541
ACTB_HUMAN	ACTB	physical	20348541
RL9_HUMAN	RPL9	physical	20348541
SET_HUMAN	SET	physical	20348541
GLYM_HUMAN	SHMT2	physical	20348541
ENPL_HUMAN	HSP90B1	physical	20348541
TERA_HUMAN	VCP	physical	20348541
SMC1A_HUMAN	SMC1A	physical	20348541
H2A2C_HUMAN	HIST2H2AC	physical	20348541
GRWD1_HUMAN	GRWD1	physical	20348541
SARNP_HUMAN	SARNP	physical	20348541
TBA1C_HUMAN	TUBA1C	physical	20348541
FBH1_HUMAN	FBXO18	physical	20348541
SYYC_HUMAN	YARS	physical	20348541
FUBP1_HUMAN	FUBP1	physical	20348541
IF2B_HUMAN	EIF2S2	physical	20348541
SMC3_HUMAN	SMC3	physical	20348541
MED27_HUMAN	MED27	physical	20348541
IF4A3_HUMAN	EIF4A3	physical	20348541
BCAS3_HUMAN	BCAS3	physical	17505058
DAAF4_HUMAN	DYX1C1	physical	19423554
CAV1_HUMAN	CAV1	physical	22230296
GNAI1_HUMAN	GNAI1	physical	22230296
GNAI2_HUMAN	GNAI2	physical	22230296
GNAI3_HUMAN	GNAI3	physical	22230296
NCOA1_HUMAN	NCOA1	physical	10454579
NCOA1_HUMAN	NCOA1	physical	15604093
SPT6H_HUMAN	SUPT6H	physical	24441044
BRE1B_HUMAN	RNF40	physical	24441044
FOXK2_HUMAN	FOXK2	physical	25740706
BARD1_HUMAN	BARD1	physical	25740706
NCOA1_HUMAN	NCOA1	physical	9121466
NCOA3_HUMAN	NCOA3	physical	16331275
ANGL4_HUMAN	ANGPTL4	physical	25640309
ATAD2_HUMAN	ATAD2	physical	25640309
BAP1_HUMAN	BAP1	physical	25640309
GROA_HUMAN	CXCL1	physical	25640309
ESIP1_HUMAN	EPSTI1	physical	25640309
GLCE_HUMAN	GLCE	physical	25640309
KLK5_HUMAN	KLK5	physical	25640309
KLK9_HUMAN	KLK9	physical	25640309
HOP2_HUMAN	PSMC3IP	physical	25640309
SPB5_HUMAN	SERPINB5	physical	25640309
NSD3_HUMAN	WHSC1L1	physical	25640309
COF1_HUMAN	CFL1	physical	25640309
CSRP1_HUMAN	CSRP1	physical	25640309
HBP1_HUMAN	HBP1	physical	25640309
UBE4B_HUMAN	UBE4B	physical	25640309
TBG1_HUMAN	TUBG1	physical	25499220
BRCA1_HUMAN	BRCA1	physical	25499220
RAD51_HUMAN	RAD51	physical	25499220
HECD1_HUMAN	HECTD1	physical	26389696
P2R3A_HUMAN	PPP2R3A	physical	26389696
SASH1_HUMAN	SASH1	physical	26389696
UBE3C_HUMAN	UBE3C	physical	26389696
UBP16_HUMAN	USP16	physical	26389696
SUZ12_HUMAN	SUZ12	physical	26389696
NDC80_HUMAN	NDC80	physical	26389696
ZN182_HUMAN	ZNF182	physical	26389696
TAB3_HUMAN	TAB3	physical	26389696
2AAA_HUMAN	PPP2R1A	physical	26389696
CH60_HUMAN	HSPD1	physical	26389696
TRXR1_HUMAN	TXNRD1	physical	26389696
PATZ1_HUMAN	PATZ1	physical	26389696
PP2AA_HUMAN	PPP2CA	physical	26389696
PP2AB_HUMAN	PPP2CB	physical	26389696
TRAF3_HUMAN	TRAF3	physical	26186972
TBK1_HUMAN	TBK1	physical	26186972
IKKE_HUMAN	IKBKE	physical	26186972
FBSP1_HUMAN	FBXO45	physical	26487511
NCOA1_HUMAN	NCOA1	physical	26487511
NCOA2_HUMAN	NCOA2	physical	26487511
NCOA3_HUMAN	NCOA3	physical	26487511
NCOA6_HUMAN	NCOA6	physical	26487511
TTK_HUMAN	TTK	physical	26487511
CHD6_HUMAN	CHD6	physical	26487511
MED12_HUMAN	MED12	physical	26487511
MPRIP_HUMAN	MPRIP	physical	26487511
RSMN_HUMAN	SNRPN	physical	26487511
TMOD3_HUMAN	TMOD3	physical	26487511
AGFG1_HUMAN	AGFG1	physical	26487511
IF6_HUMAN	EIF6	physical	26487511
GCN1_HUMAN	GCN1L1	physical	26487511
COR1C_HUMAN	CORO1C	physical	26487511
RAD50_HUMAN	RAD50	physical	26487511
PRP8_HUMAN	PRPF8	physical	26487511
TCPB_HUMAN	CCT2	physical	26487511
CATA_HUMAN	CAT	physical	26487511
AP2A2_HUMAN	AP2A2	physical	26487511
STOM_HUMAN	STOM	physical	26487511
GBB1_HUMAN	GNB1	physical	26487511
GBB2_HUMAN	GNB2	physical	26487511
GBB4_HUMAN	GNB4	physical	26487511
HNRPQ_HUMAN	SYNCRIP	physical	26487511
NAT10_HUMAN	NAT10	physical	26487511
MED9_HUMAN	MED9	physical	26487511
PRR12_HUMAN	PRR12	physical	26487511
BCOR_HUMAN	BCOR	physical	26487511
YTHD1_HUMAN	YTHDF1	physical	26487511
HXD9_HUMAN	HOXD9	physical	26487511
HXC10_HUMAN	HOXC10	physical	26487511
NFYA_HUMAN	NFYA	physical	26487511
E2F6_HUMAN	E2F6	physical	26487511
RL8_HUMAN	RPL8	physical	26487511
HNRH2_HUMAN	HNRNPH2	physical	26487511
THOC4_HUMAN	ALYREF	physical	26487511
HDAC3_HUMAN	HDAC3	physical	26487511
CBR1_HUMAN	CBR1	physical	26487511
FIP1_HUMAN	FIP1L1	physical	26487511
TIA1_HUMAN	TIA1	physical	26487511
SMC2_HUMAN	SMC2	physical	26166704
CND3_HUMAN	NCAPG	physical	26166704
CNDH2_HUMAN	NCAPH2	physical	26166704
NCOA3_HUMAN	NCOA3	physical	26166704
NRIP1_HUMAN	NRIP1	physical	26166704
SMC4_HUMAN	SMC4	physical	26166704
CND1_HUMAN	NCAPD2	physical	26166704
CND2_HUMAN	NCAPH	physical	26166704
CNDD3_HUMAN	NCAPD3	physical	26166704
CNDG2_HUMAN	NCAPG2	physical	26166704
HECD1_HUMAN	HECTD1	physical	26166704
EP300_HUMAN	EP300	physical	25728767
NCOA3_HUMAN	NCOA3	physical	25728767
PHB2_HUMAN	PHB2	physical	26052702
AHR_HUMAN	AHR	physical	19460354
NCOA2_HUMAN	NCOA2	physical	19460354
SPOP_HUMAN	SPOP	physical	25766326
DCAF1_HUMAN	VPRBP	physical	28068668
LATS1_HUMAN	LATS1	physical	28068668
DCA13_HUMAN	DCAF13	physical	28068668
JUN_HUMAN	JUN	physical	23747343
PP14C_HUMAN	PPP1R14C	physical	28514442
GBP1_HUMAN	GBP1	physical	28514442
PGK2_HUMAN	PGK2	physical	28514442
SIG10_HUMAN	SIGLEC10	physical	28514442
PNMT_HUMAN	PNMT	physical	28514442
CNDP1_HUMAN	CNDP1	physical	28514442
TAB2_HUMAN	TAB2	physical	27992601
RPTOR_HUMAN	RPTOR	physical	26522726
MTOR_HUMAN	MTOR	physical	26522726
UBE3A_HUMAN	UBE3A	physical	16772533
WBP2_HUMAN	WBP2	physical	16772533
HSP72_HUMAN	HSPA2	physical	27483141
GRP78_HUMAN	HSPA5	physical	27483141
HSP76_HUMAN	HSPA6	physical	27483141
HSP7C_HUMAN	HSPA8	physical	27483141
GRP75_HUMAN	HSPA9	physical	27483141
HS90A_HUMAN	HSP90AA1	physical	27483141
HS90B_HUMAN	HSP90AB1	physical	27483141
HS105_HUMAN	HSPH1	physical	27483141
HSP74_HUMAN	HSPA4	physical	27483141
HS74L_HUMAN	HSPA4L	physical	27483141
DNJA2_HUMAN	DNAJA2	physical	27483141
DNJA3_HUMAN	DNAJA3	physical	27483141
DNJB1_HUMAN	DNAJB1	physical	27483141
DNJB4_HUMAN	DNAJB4	physical	27483141
DNJB6_HUMAN	DNAJB6	physical	27483141
DNJC7_HUMAN	DNAJC7	physical	27483141
DNJC9_HUMAN	DNAJC9	physical	27483141
DJC10_HUMAN	DNAJC10	physical	27483141
HSPB8_HUMAN	HSPB8	physical	27483141
CH10_HUMAN	HSPE1	physical	27483141
CHIP_HUMAN	STUB1	physical	27483141
FKBP5_HUMAN	FKBP5	physical	27483141
TEBP_HUMAN	PTGES3	physical	27483141
FOXA1_HUMAN	FOXA1	physical	28336670
PBX1_HUMAN	PBX1	physical	28336670
KMT2D_HUMAN	KMT2D	physical	28336670
NCOA3_HUMAN	NCOA3	physical	28844863

Drug and Disease Associations

• Kegg Disease
• H00026: Endometrial Cancer
• OMIM Disease
• 615363: Estrogen resistance (ESTRR)
• Kegg Drug
• D00067: Estrone (JAN/USP/INN); Estrone (TN)
• D00105: Estradiol (JAN/USP/INN); Climara (TN); Divigel (TN); Estrace (TN); Estraderm (TN); Estrasorb (TN); E
• D00185: Estriol (JP16/USP); Estriel (TN)
• D00312: Estrone sodium sulfate; Sodium estrone sulfate
• D00554: Ethinylestradiol (JP16/INN); Ethinyl estradiol (USP); Estinyl (TN)
• D00575: Mestranol (JP16/USP/INN)
• D00577: Diethylstilbestrol (USP/INN); Stilbestrol (TN)
• D00898: Dienestrol (USP/INN); DV (TN)
• D00946: Fosfestrol (JAN/INN); Diethylstilbestrol diphosphate (USP); Stilphostrol (TN)
• D00948: Estropipate (USP); Piperazine estrone sulfate; Ogen (TN)
• D00962: Clomifene citrate (JP16); Clomiphene citrate (USP); Clomid (TN); Serophene (TN)
• D00963: Exemestane (JAN/USP/INN); Aromasin (TN)
• D00964: Letrozole (JAN/USP/INN); Femara (TN)
• D00966: Tamoxifen citrate (JP16/USP); Nolvadex (TN)
• D00967: Toremifene citrate (JAN/USAN); Fareston (TN)
• D01161: Fulvestrant (JAN/USAN/INN); Faslodex (TN)
• D01265: Epitiostanol (JAN/INN)
• D01413: Estradiol valerate (JAN/USP/INN); Deladumone (TN)
• D01602: Mepitiostane (JP16/INN); Thioderon (TN)
• D01617: Estradiol dipropionate (JAN); Ovahormon (TN)
• D01639: Tibolone (JAN/USAN/INN)
• D01953: Estradiol benzoate (JP16); Ovahormon (TN)
• D01986: Estriol tripropionate (JAN); Estriol (TN)
• D01989: Estriol diacetate benzoate (JAN); Estriol benzoate diacetate; Holin (TN)
• D02217: Raloxifene hydrochloride (JAN/USP); LY 156758; Evista (TN)
• D02758: Acolbifene hydrochloride (USAN)
• D02993: Arzoxifene hydrochloride (USAN)
• D03062: Bazedoxifene acetate (JAN/USAN); Viviant (TN)
• D03911: Droloxifene (USAN/INN)
• D03912: Droloxifene citrate (USAN)
• D04041: Equilin (USP)
• D04061: Estradiol acetate (USAN); Femring (TN)
• D04063: Estradiol cypionate (USP); Depo-estradiol (TN)
• D04064: Estradiol enanthate (USAN)
• D04065: Estradiol undecylate (USAN/INN); Delestrec (TN)
• D04070: Conjugated estrogens (JAN); Estrogens, conjugated (USP); Premarin (TN)
• D04071: Estrogens, esterified (USP); Amnestrogen (TN)
• D04496: Idoxifene (USAN/INN)
• D04672: Lasofoxifene tartrate (JAN/USAN)
• D05106: Nafoxidine hydrochloride (USAN)
• D05192: Nitromifene citrate (USAN)
• D05987: Synthetic conjugated estrogens, B (USAN); Enjuvia (TN)
• D06245: Trioxifene mesylate (USAN)
• D06551: Afimoxifene (USAN/INN); Tamogel (TN)
• D07221: Promestriene (INN); Colpotrophine (TN)
• D07434: Polyestradiol phosphate (INN); Estradurin (TN)
• D07726: Clomifene (INN); Clomiphene; Clomifene (TN)
• D07826: Hexestrol diphosphate sodium; Diethylstilbestrol diphosphate tetrasodium salt; Stilphostrol (TN)
• D07918: Estradiol hemihydrate; Estrasorb (TN); Vagifem (TN)
• D07919: Estradiol 17 beta-hemisuccinate; 17beta-Estradiol hemisuccinate; Eutocol (TN)
• D07920: Estriol succinate; Estriol 16alfa, 17beta-di (hydrogen succinate); Sinapause (TN)
• D07921: Estriol sodium succinate (BAN); Estriol 16alpha, 17beta-di (sodium succinate); Styptanon (TN)
• D07928: Ethinylestradiol propanesulfonate; Turisteron (TN)
• D08301: Ormeloxifene (INN); Centron (TN)
• D08465: Raloxifene (INN); Eviden (TN); Raxeto (TN)
• D08559: Tamoxifen (INN); Tamoxifen (TN); Tamoplex (TN)
• D08620: Toremifene (INN); Fareston (TN)
• D08910: Enclomiphene (USAN)
• D08958: Ospemifene (INN/USAN/BAN); Osphena (TN)
• D09834: Levormeloxifene fumarate (JAN)
• D10008: Fispemifene (USAN/INN)
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Methylation

"Regulation of estrogen rapid signaling through arginine methylationby PRMT1.";
Le Romancer M., Treilleux I., Leconte N., Robin-Lespinasse Y.,Sentis S., Bouchekioua-Bouzaghou K., Goddard S., Gobert-Gosse S.,Corbo L.;
Mol. Cell 31:212-221(2008).
Cited for: METHYLATION AT ARG-260 BY PRMT1, MUTAGENESIS OF ARG-260, SUBCELLULARLOCATION, AND INTERACTION WITH PI3KR1/2; SRC AND PTK2/FAK1.
PubMed: 18657504

Phosphorylation

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-7 AND SER-10, AND MASSSPECTROMETRY.
PubMed: 18187866

"Potentiation of human estrogen receptor alpha transcriptionalactivation through phosphorylation of serines 104 and 106 by thecyclin A-CDK2 complex.";
Rogatsky I., Trowbridge J.M., Garabedian M.J.;
J. Biol. Chem. 274:22296-22302(1999).
Cited for: PHOSPHORYLATION AT SER-104 AND SER-106, AND MUTAGENESIS.
PubMed: 10428798