dbPTM

TSC1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TSC1_HUMAN
UniProt AC	Q92574
Protein Name	Hamartin
Gene Name	TSC1
Organism	Homo sapiens (Human).
Sequence Length	1164
Subcellular Localization	Cytoplasm . Membrane Peripheral membrane protein . At steady state found in association with membranes.
Protein Description	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. [PubMed: 12271141]
Protein Sequence	MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
79	Phosphorylation	LLDRINEYVGKAATR HHHHHHHHHHHHHHH	15.26	-
91	Phosphorylation	ATRLSILSLLGHVIR HHHHHHHHHHHHHHH	21.63	-
102	Phosphorylation	HVIRLQPSWKHKLSQ HHHHHCCHHHCCCCC	35.48	24719451
108	Phosphorylation	PSWKHKLSQAPLLPS CHHHCCCCCCCCHHH	29.15	24719451
115	Phosphorylation	SQAPLLPSLLKCLKM CCCCCHHHHHHHHCC	46.43	24719451
205	Phosphorylation	NFVSFLRSHYSMKEN HHHHHHHHCCCHHHH	28.99	-
221	Ubiquitination	ETFEEVVKPMMEHVR HHHHHHHHHHHHHCC	32.16	-
238	Ubiquitination	PELVTGSKDHELDPR HHHHCCCCCCCCCHH	65.53	-
267	Phosphorylation	AKISLDPTEASYEDG EEEECCCCCCCCCCC	43.80	21712546
270	Phosphorylation	SLDPTEASYEDGYSV ECCCCCCCCCCCCCE	23.87	25159151
271	Phosphorylation	LDPTEASYEDGYSVS CCCCCCCCCCCCCEE	25.70	21712546
275	Phosphorylation	EASYEDGYSVSHQIS CCCCCCCCCEEEEHH	20.44	21712546
276	Phosphorylation	ASYEDGYSVSHQISA CCCCCCCCEEEEHHC	23.75	27080861
278	Phosphorylation	YEDGYSVSHQISARF CCCCCCEEEEHHCCC	12.06	22210691
282	Phosphorylation	YSVSHQISARFPHRS CCEEEEHHCCCCCCC	13.56	25159151
289	Phosphorylation	SARFPHRSADVTTSP HCCCCCCCCCCCCCC	26.28	28270605
293	Phosphorylation	PHRSADVTTSPYADT CCCCCCCCCCCCCCC	23.31	28270605
294	Phosphorylation	HRSADVTTSPYADTQ CCCCCCCCCCCCCCC	27.79	28450419
295	Phosphorylation	RSADVTTSPYADTQN CCCCCCCCCCCCCCC	13.42	28450419
297	Phosphorylation	ADVTTSPYADTQNSY CCCCCCCCCCCCCCC	19.51	28450419
300	Phosphorylation	TTSPYADTQNSYGCA CCCCCCCCCCCCCCC	22.83	28450419
303	Phosphorylation	PYADTQNSYGCATST CCCCCCCCCCCCCCC	17.06	28450419
304	Phosphorylation	YADTQNSYGCATSTP CCCCCCCCCCCCCCC	24.63	28450419
310	Phosphorylation	SYGCATSTPYSTSRL CCCCCCCCCCCCCEE	23.14	22817900
312	Phosphorylation	GCATSTPYSTSRLML CCCCCCCCCCCEEEH	25.35	22817900
329	Phosphorylation	MPGQLPQTLSSPSTR CCCCCCCCCCCCCCC	27.03	28450419
331	Phosphorylation	GQLPQTLSSPSTRLI CCCCCCCCCCCCCCC	43.52	28450419
332	Phosphorylation	QLPQTLSSPSTRLIT CCCCCCCCCCCCCCC	26.44	28450419
334	Phosphorylation	PQTLSSPSTRLITEP CCCCCCCCCCCCCCC	28.27	28450419
335	Phosphorylation	QTLSSPSTRLITEPP CCCCCCCCCCCCCCC	32.64	28450419
348	Phosphorylation	PPQATLWSPSMVCGM CCCCCCCCCCCCCCC	15.37	28634298
350	Phosphorylation	QATLWSPSMVCGMTT CCCCCCCCCCCCCCC	20.52	24850871
356	Phosphorylation	PSMVCGMTTPPTSPG CCCCCCCCCCCCCCC	22.79	22199227
357	Phosphorylation	SMVCGMTTPPTSPGN CCCCCCCCCCCCCCC	20.55	22199227
360	Phosphorylation	CGMTTPPTSPGNVPP CCCCCCCCCCCCCCC	49.08	22199227
361	Phosphorylation	GMTTPPTSPGNVPPD CCCCCCCCCCCCCCC	36.26	22199227
370	Phosphorylation	GNVPPDLSHPYSKVF CCCCCCCCCCCHHHC	29.78	26074081
373	Phosphorylation	PPDLSHPYSKVFGTT CCCCCCCCHHHCCCC	18.72	26074081
374	Phosphorylation	PDLSHPYSKVFGTTA CCCCCCCHHHCCCCC	27.13	26074081
379	Phosphorylation	PYSKVFGTTAGGKGT CCHHHCCCCCCCCCC	11.29	26074081
380	Phosphorylation	YSKVFGTTAGGKGTP CHHHCCCCCCCCCCC	24.55	26074081
386	Phosphorylation	TTAGGKGTPLGTPAT CCCCCCCCCCCCCCC	20.87	28450419
390	Phosphorylation	GKGTPLGTPATSPPP CCCCCCCCCCCCCCC	19.89	25159151
393	Phosphorylation	TPLGTPATSPPPAPL CCCCCCCCCCCCCCC	42.86	25159151
394	Phosphorylation	PLGTPATSPPPAPLC CCCCCCCCCCCCCCC	37.20	25159151
403	Phosphorylation	PPAPLCHSDDYVHIS CCCCCCCCCCEEEEE	31.05	28464451
406	Phosphorylation	PLCHSDDYVHISLPQ CCCCCCCEEEEECCC	10.02	28464451
410	Phosphorylation	SDDYVHISLPQATVT CCCEEEEECCCCCCC	21.08	28796482
415	Phosphorylation	HISLPQATVTPPRKE EEECCCCCCCCCCHH	21.47	20873877
417	Phosphorylation	SLPQATVTPPRKEER ECCCCCCCCCCHHHH	24.18	14551205
427	Phosphorylation	RKEERMDSARPCLHR CHHHHHHCCCHHHHH	19.48	25159151
444	Phosphorylation	HLLNDRGSEEPPGSK HHHCCCCCCCCCCCC	39.41	28674419
455	Phosphorylation	PGSKGSVTLSDLPGF CCCCCCEEHHHCCCH	23.42	28464451
468	Phosphorylation	GFLGDLASEEDSIEK CHHHHHCCCCCHHHH	49.14	28192239
472	Phosphorylation	DLASEEDSIEKDKEE HHCCCCCHHHHHHHH	35.61	28192239
477	Ubiquitination	EDSIEKDKEEAAISR CCHHHHHHHHHHHHH	69.40	21906983
483	Phosphorylation	DKEEAAISRELSEIT HHHHHHHHHHHHHHH	18.25	21815630
487	Phosphorylation	AAISRELSEITTAEA HHHHHHHHHHHCCCC	23.38	21815630
490	Phosphorylation	SRELSEITTAEAEPV HHHHHHHHCCCCCCC	18.85	27732954
491	Phosphorylation	RELSEITTAEAEPVV HHHHHHHCCCCCCCC	28.32	21815630
505	Phosphorylation	VPRGGFDSPFYRDSL CCCCCCCCCCCCCCC	18.04	19664994
508	Phosphorylation	GGFDSPFYRDSLPGS CCCCCCCCCCCCCCC	19.52	23927012
511	Phosphorylation	DSPFYRDSLPGSQRK CCCCCCCCCCCCCCC	27.71	25159151
515	Phosphorylation	YRDSLPGSQRKTHSA CCCCCCCCCCCCCCC	25.52	23403867
519	Phosphorylation	LPGSQRKTHSAASSS CCCCCCCCCCCCCCC	24.21	23403867
521	Phosphorylation	GSQRKTHSAASSSQG CCCCCCCCCCCCCCC	30.66	25159151
524	Phosphorylation	RKTHSAASSSQGASV CCCCCCCCCCCCCCC	30.18	23403867
525	Phosphorylation	KTHSAASSSQGASVN CCCCCCCCCCCCCCC	23.19	23403867
526	Phosphorylation	THSAASSSQGASVNP CCCCCCCCCCCCCCC	30.09	23403867
530	Phosphorylation	ASSSQGASVNPEPLH CCCCCCCCCCCHHCC	29.29	23401153
538	Phosphorylation	VNPEPLHSSLDKLGP CCCHHCCHHHHHHCC	40.03	25849741
539	Phosphorylation	NPEPLHSSLDKLGPD CCHHCCHHHHHHCCC	29.82	23403867
547	Phosphorylation	LDKLGPDTPKQAFTP HHHHCCCCCCCCCCC	35.20	29255136
561	Phosphorylation	PIDLPCGSADESPAG CCCCCCCCCCCCCCC	38.98	28348404
565	Phosphorylation	PCGSADESPAGDREC CCCCCCCCCCCCCCC	22.16	21815630
574	Phosphorylation	AGDRECQTSLETSIF CCCCCCCCCCCEECC	47.11	27080861
575	Phosphorylation	GDRECQTSLETSIFT CCCCCCCCCCEECCC	9.79	28348404
578	Phosphorylation	ECQTSLETSIFTPSP CCCCCCCEECCCCCC	32.20	27080861
579	Phosphorylation	CQTSLETSIFTPSPC CCCCCCEECCCCCCC	13.31	28348404
582	Phosphorylation	SLETSIFTPSPCKIP CCCEECCCCCCCCCC	22.61	27080861
584	Phosphorylation	ETSIFTPSPCKIPPP CEECCCCCCCCCCCC	39.61	14551205
598	Phosphorylation	PTRVGFGSGQPPPYD CCCCCCCCCCCCCCC	31.81	25159151
604	Phosphorylation	GSGQPPPYDHLFEVA CCCCCCCCCCCEEHH	23.05	22199227
624	Phosphorylation	HHFVIRKTEELLKKA CCHHHHCHHHHHHHH	25.50	24702127
643	Phosphorylation	EEDGVPSTSPMEVLD CCCCCCCCCHHHHHH	30.68	25627689
644	Phosphorylation	EDGVPSTSPMEVLDR CCCCCCCCHHHHHHH	26.96	25627689
662	Ubiquitination	QGADAHSKELNKLPL CCHHHCHHHHHCCCC	57.25	-
671	Phosphorylation	LNKLPLPSKSVDWTH HHCCCCCCCCCCCCC	45.29	24719451
672	Ubiquitination	NKLPLPSKSVDWTHF HCCCCCCCCCCCCCC	53.19	-
673	Phosphorylation	KLPLPSKSVDWTHFG CCCCCCCCCCCCCCC	29.64	29507054
677	Phosphorylation	PSKSVDWTHFGGSPP CCCCCCCCCCCCCCC	11.67	26270265
682	Phosphorylation	DWTHFGGSPPSDEIR CCCCCCCCCCHHHHH	33.73	22199227
725	Ubiquitination	RLLRKVIKAAALEEH HHHHHHHHHHHHHHH	34.65	21906983
737	Ubiquitination	EEHNAAMKDQLKLQE HHHHHHHHHHHHHHH	37.28	-
751	Acetylation	EKDIQMWKVSLQKEQ HHHHHHHHHHHHHHH	19.32	19822327
756	Ubiquitination	MWKVSLQKEQARYNQ HHHHHHHHHHHHHHH	58.02	-
774	Ubiquitination	QRDTMVTKLHSQIRQ HHHHHHHHHHHHHHH	32.56	-
871	Phosphorylation	EQLQNKHSDTTKEVE HHHHHCCCCCHHHHH	37.96	-
873	Phosphorylation	LQNKHSDTTKEVEMM HHHCCCCCHHHHHHH	42.66	-
874	Phosphorylation	QNKHSDTTKEVEMMK HHCCCCCHHHHHHHH	30.14	-
928	Ubiquitination	HLLLEQKKYLEDVKL HHHHHHHHHHHHHHH	55.55	-
934	Ubiquitination	KKYLEDVKLQARGQL HHHHHHHHHHHHHHH	47.40	-
1001	Phosphorylation	DCCNDGCSDSMVGHN HHCCCCCCHHHCCCC	37.94	21601212
1020	Phosphorylation	GHNGETKTPRPSSAR CCCCCCCCCCCCCCC	31.76	21712546
1024	Phosphorylation	ETKTPRPSSARGSSG CCCCCCCCCCCCCCC	37.60	-
1025	Phosphorylation	TKTPRPSSARGSSGS CCCCCCCCCCCCCCC	25.35	22985185
1029	Phosphorylation	RPSSARGSSGSRGGG CCCCCCCCCCCCCCC	26.44	21712546
1030	Phosphorylation	PSSARGSSGSRGGGG CCCCCCCCCCCCCCC	43.54	21712546
1033	Methylation	ARGSSGSRGGGGSSS CCCCCCCCCCCCCCC	51.83	115919049
1038	Phosphorylation	GSRGGGGSSSSSSEL CCCCCCCCCCCCCCC	30.26	23927012
1039	Phosphorylation	SRGGGGSSSSSSELS CCCCCCCCCCCCCCC	37.20	23927012
1040	Phosphorylation	RGGGGSSSSSSELST CCCCCCCCCCCCCCC	35.62	23927012
1041	Phosphorylation	GGGGSSSSSSELSTP CCCCCCCCCCCCCCC	39.57	26657352
1042	Phosphorylation	GGGSSSSSSELSTPE CCCCCCCCCCCCCCC	29.76	30576142
1043	Phosphorylation	GGSSSSSSELSTPEK CCCCCCCCCCCCCCC	44.50	23927012
1046	Phosphorylation	SSSSSELSTPEKPPH CCCCCCCCCCCCCCC	37.55	23927012
1047	Phosphorylation	SSSSELSTPEKPPHQ CCCCCCCCCCCCCCC	48.36	14551205
1071	Phosphorylation	ETTMGEASASIPTTV EECCCCHHHCCCCCC	20.46	26074081
1073	Phosphorylation	TMGEASASIPTTVGS CCCCHHHCCCCCCCC	26.97	29978859
1076	Phosphorylation	EASASIPTTVGSLPS CHHHCCCCCCCCCCC	32.23	25850435
1077	Phosphorylation	ASASIPTTVGSLPSS HHHCCCCCCCCCCCC	19.95	27050516
1080	Phosphorylation	SIPTTVGSLPSSKSF CCCCCCCCCCCCCHH	32.54	30576142
1083	Phosphorylation	TTVGSLPSSKSFLGM CCCCCCCCCCHHHCH	56.54	25850435
1084	Phosphorylation	TVGSLPSSKSFLGMK CCCCCCCCCHHHCHH	30.31	25850435
1086	Phosphorylation	GSLPSSKSFLGMKAR CCCCCCCHHHCHHHH	27.87	26074081
1100	Phosphorylation	RELFRNKSESQCDED HHHHHCCCHHHCCCC	46.13	23401153
1102	Phosphorylation	LFRNKSESQCDEDGM HHHCCCHHHCCCCCC	43.11	17525332
1110	Phosphorylation	QCDEDGMTSSLSESL HCCCCCCCHHHHHHH	22.24	23312004
1111	Phosphorylation	CDEDGMTSSLSESLK CCCCCCCHHHHHHHH	22.01	23312004
1112	Phosphorylation	DEDGMTSSLSESLKT CCCCCCHHHHHHHHH	27.09	23312004
1114	Phosphorylation	DGMTSSLSESLKTEL CCCCHHHHHHHHHHH	27.38	23312004
1116	Phosphorylation	MTSSLSESLKTELGK CCHHHHHHHHHHHCC	31.61	-
1141	Phosphorylation	NLDGPHPSPPTPDSV CCCCCCCCCCCCCCC	40.24	30576142
1144	Phosphorylation	GPHPSPPTPDSVGQL CCCCCCCCCCCCCEE	43.01	28555341
1147	Phosphorylation	PSPPTPDSVGQLHIM CCCCCCCCCCEEEEE	29.38	27080861
1156	Phosphorylation	GQLHIMDYNETHHEH CEEEEECCCCCCCCC	9.49	27080861
1159	Phosphorylation	HIMDYNETHHEHS-- EEECCCCCCCCCC--	25.54	27080861

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
417	T	Phosphorylation	Kinase	CDK1	P06493	PSP
468	S	Phosphorylation	Kinase	PLK1	P53350	PSP
487	S	Phosphorylation	Kinase	IKBKB	O14920	GPS
511	S	Phosphorylation	Kinase	IKBKB	O14920	GPS
579	S	Phosphorylation	Kinase	PLK1	P53350	PSP
584	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1047	T	Phosphorylation	Kinase	CDK1	P06493	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
505	S	Phosphorylation		15963462
Phosphorylation at Ser-505 does not affect interaction with TSC2.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TSC1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
1433Z_HUMAN	YWHAZ	physical	12176984
EZRI_HUMAN	EZR	physical	10806479
ACTS_HUMAN	ACTA1	physical	10806479
AKT1_HUMAN	AKT1	physical	15342917
NFL_HUMAN	NEFL	physical	12226091
PLK1_HUMAN	PLK1	physical	16339216
RHEB_HUMAN	RHEB	physical	12820960
KS6A1_HUMAN	RPS6KA1	physical	15342917
TSC1_HUMAN	TSC1	physical	10585443
TSC2_HUMAN	TSC2	physical	15851026
TSC2_HUMAN	TSC2	physical	14651849
TSC2_HUMAN	TSC2	physical	15963462
TSC2_HUMAN	TSC2	physical	16424383
TSC2_HUMAN	TSC2	physical	16339216
TSC2_HUMAN	TSC2	physical	17077083
TSC2_HUMAN	TSC2	physical	14551205
TSC2_HUMAN	TSC2	physical	11741833
TSC2_HUMAN	TSC2	physical	11741832
TSC2_HUMAN	TSC2	physical	11290735
TSC2_HUMAN	TSC2	physical	10807585
TSC2_HUMAN	TSC2	physical	9580671
TSC2_HUMAN	TSC2	physical	12167664
DOCK7_HUMAN	DOCK7	physical	15963462
TSC2_HUMAN	TSC2	physical	10915759
TSC2_HUMAN	TSC2	physical	17658474
TBCD7_HUMAN	TBC1D7	physical	17658474
TSC2_HUMAN	TSC2	physical	11175345
BEX3_HUMAN	NGFRAP1	physical	17355907
MK14_HUMAN	MAPK14	physical	20368287
KDM1A_HUMAN	KDM1A	physical	23455924
ANM6_HUMAN	PRMT6	physical	23455924
TSC2_HUMAN	TSC2	physical	20166753
TSC2_HUMAN	TSC2	physical	21134130
DAPK1_HUMAN	DAPK1	physical	21134130
VHL_HUMAN	VHL	genetic	28319113
CPVL_HUMAN	CPVL	physical	28561026
DYR1A_HUMAN	DYRK1A	physical	28561026
PCM1_HUMAN	PCM1	physical	28561026
PIHD1_HUMAN	PIH1D1	physical	28561026
RPAP3_HUMAN	RPAP3	physical	28561026
RUVB1_HUMAN	RUVBL1	physical	28561026
RUVB2_HUMAN	RUVBL2	physical	28561026
TBCD7_HUMAN	TBC1D7	physical	28561026
TSC1_HUMAN	TSC1	physical	28561026
TSC2_HUMAN	TSC2	physical	28561026
RMP_HUMAN	URI1	physical	28561026
WDR92_HUMAN	WDR92	physical	28561026

Drug and Disease Associations

Kegg Disease
H00896	Lymphangioleiomyomatosis (LAM)
H00915	Tuberous sclerosis complex (TSC); Bourneville-Pringle disease
H01251	Focal cortical dysplasia of Taylor; Focal cortical dysplasia type II
OMIM Disease
191100	Tuberous sclerosis 1 (TSC1)
607341	Focal cortical dysplasia of Taylor balloon cell type (FCDBC)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TSC1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-505, AND MASSSPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-505 AND SER-1102, ANDMASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-505; SER-511 ANDSER-598, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Phosphoproteome of resting human platelets."; Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J.,Schuetz C., Walter U., Gambaryan S., Sickmann A.; J. Proteome Res. 7:526-534(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-505, AND MASSSPECTROMETRY.	18088087 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1102, AND MASSSPECTROMETRY.	17525332 [Abstract]
"Phosphorylation and binding partner analysis of the TSC1-TSC2complex."; Nellist M., Burgers P.C., van den Ouweland A.M.W., Halley D.J.J.,Luider T.M.; Biochem. Biophys. Res. Commun. 333:818-826(2005). Cited for: PHOSPHORYLATION AT SER-505, MASS SPECTROMETRY, AND INTERACTION WITHDOCK7 AND TSC2.	15963462 [Abstract]

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