dbPTM

EZRI_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	EZRI_HUMAN
UniProt AC	P15311
Protein Name	Ezrin
Gene Name	EZR
Organism	Homo sapiens (Human).
Sequence Length	586
Subcellular Localization	Apical cell membrane Peripheral membrane protein Cytoplasmic side . Cell projection . Cell projection, microvillus membrane Peripheral membrane protein Cytoplasmic side . Cell projection, ruffle membrane Peripheral membrane protein Cytoplasmic
Protein Description	Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis..
Protein Sequence	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Ubiquitination	-----MPKPINVRVT -----CCCCEEEEEE	58.17	33845483
12	Sulfoxidation	INVRVTTMDAELEFA EEEEEEECCEEEEEE	3.16	21406390
26	Ubiquitination	AIQPNTTGKQLFDQV EECCCCCHHHHHHHH	17.42	23000965
27	Ubiquitination	IQPNTTGKQLFDQVV ECCCCCHHHHHHHHH	41.56	23503661
35	Acetylation	QLFDQVVKTIGLREV HHHHHHHHHHCCHHH	35.25	23954790
35	Ubiquitination	QLFDQVVKTIGLREV HHHHHHHHHHCCHHH	35.25	23000965
48	Ubiquitination	EVWYFGLHYVDNKGF HHEEEEEEEECCCCC	22.43	23503661
49	Phosphorylation	VWYFGLHYVDNKGFP HEEEEEEEECCCCCC	17.97	28152594
57	Phosphorylation	VDNKGFPTWLKLDKK ECCCCCCCCCCCCCC	40.96	29514088
60	Acetylation	KGFPTWLKLDKKVSA CCCCCCCCCCCCCCH	46.32	19608861
60	Malonylation	KGFPTWLKLDKKVSA CCCCCCCCCCCCCCH	46.32	26320211
60	Succinylation	KGFPTWLKLDKKVSA CCCCCCCCCCCCCCH	46.32	23954790
60	Ubiquitination	KGFPTWLKLDKKVSA CCCCCCCCCCCCCCH	46.32	-
64	Ubiquitination	TWLKLDKKVSAQEVR CCCCCCCCCCHHHHH	40.88	27667366
66	Phosphorylation	LKLDKKVSAQEVRKE CCCCCCCCHHHHHHH	32.87	23403867
72	Acetylation	VSAQEVRKENPLQFK CCHHHHHHHCCCCEE	68.00	23236377
72	Malonylation	VSAQEVRKENPLQFK CCHHHHHHHCCCCEE	68.00	26320211
72	Ubiquitination	VSAQEVRKENPLQFK CCHHHHHHHCCCCEE	68.00	33845483
73	Ubiquitination	SAQEVRKENPLQFKF CHHHHHHHCCCCEEE	54.22	21963094
75	Ubiquitination	QEVRKENPLQFKFRA HHHHHHCCCCEEEEE	28.73	22817900
76	Ubiquitination	EVRKENPLQFKFRAK HHHHHCCCCEEEEEC	16.42	22817900
79	Acetylation	KENPLQFKFRAKFYP HHCCCCEEEEECCCC	22.45	23954790
79	Malonylation	KENPLQFKFRAKFYP HHCCCCEEEEECCCC	22.45	26320211
79	Neddylation	KENPLQFKFRAKFYP HHCCCCEEEEECCCC	22.45	32015554
79	Ubiquitination	KENPLQFKFRAKFYP HHCCCCEEEEECCCC	22.45	32142685
83	Acetylation	LQFKFRAKFYPEDVA CCEEEEECCCCHHHH	40.97	25953088
83	Succinylation	LQFKFRAKFYPEDVA CCEEEEECCCCHHHH	40.97	21890473
83	Ubiquitination	LQFKFRAKFYPEDVA CCEEEEECCCCHHHH	40.97	22817900
94	Ubiquitination	EDVAEELIQDITQKL HHHHHHHHHHHHHHH	3.80	23503661
97	Ubiquitination	AEELIQDITQKLFFL HHHHHHHHHHHHHHH	2.23	23503661
101	Ubiquitination	IQDITQKLFFLQVKE HHHHHHHHHHHHHCC	2.36	21890473
107	Ubiquitination	KLFFLQVKEGILSDE HHHHHHHCCCCCCCC	36.94	-
112	Phosphorylation	QVKEGILSDEIYCPP HHCCCCCCCCCCCCH	31.14	27259358
116	Phosphorylation	GILSDEIYCPPETAV CCCCCCCCCCHHHHH	9.24	28064214
117	Glutathionylation	ILSDEIYCPPETAVL CCCCCCCCCHHHHHH	5.79	22555962
117	Ubiquitination	ILSDEIYCPPETAVL CCCCCCCCCHHHHHH	5.79	21890473
118	Ubiquitination	LSDEIYCPPETAVLL CCCCCCCCHHHHHHH	16.88	23000965
121	Phosphorylation	EIYCPPETAVLLGSY CCCCCHHHHHHHCCH	28.04	28442448
122	Ubiquitination	IYCPPETAVLLGSYA CCCCHHHHHHHCCHH	6.57	23000965
126	Ubiquitination	PETAVLLGSYAVQAK HHHHHHHCCHHHHHH	17.91	23000965
127	Ubiquitination	ETAVLLGSYAVQAKF HHHHHHCCHHHHHHH	15.19	23000965
133	Ubiquitination	GSYAVQAKFGDYNKE CCHHHHHHHCCCCCC	32.56	23000965
137	Phosphorylation	VQAKFGDYNKEVHKS HHHHHCCCCCCHHHC	28.63	28152594
139	Acetylation	AKFGDYNKEVHKSGY HHHCCCCCCHHHCCC	55.68	23236377
139	Ubiquitination	AKFGDYNKEVHKSGY HHHCCCCCCHHHCCC	55.68	23000965
143	Ubiquitination	DYNKEVHKSGYLSSE CCCCCHHHCCCCCCC	51.24	23000965
144	Phosphorylation	YNKEVHKSGYLSSER CCCCHHHCCCCCCCC	20.14	26657352
146	Dephosphorylation	KEVHKSGYLSSERLI CCHHHCCCCCCCCCC	15.53	12560083
146	Phosphorylation	KEVHKSGYLSSERLI CCHHHCCCCCCCCCC	15.53	21765462
148	Phosphorylation	VHKSGYLSSERLIPQ HHHCCCCCCCCCCCH	22.97	28152594
149	Phosphorylation	HKSGYLSSERLIPQR HHCCCCCCCCCCCHH	24.92	28152594
160	Ubiquitination	IPQRVMDQHKLTRDQ CCHHHHHHCCCCHHH	19.95	24816145
162	Acetylation	QRVMDQHKLTRDQWE HHHHHHCCCCHHHHH	46.01	25953088
162	Ubiquitination	QRVMDQHKLTRDQWE HHHHHHCCCCHHHHH	46.01	23000965
170	Ubiquitination	LTRDQWEDRIQVWHA CCHHHHHHHHHHHHH	50.45	23503661
171	Methylation	TRDQWEDRIQVWHAE CHHHHHHHHHHHHHH	15.10	-
180	Ubiquitination	QVWHAEHRGMLKDNA HHHHHHHCCCCCCCH	24.58	24816145
184	Acetylation	AEHRGMLKDNAMLEY HHHCCCCCCCHHHHH	39.79	25953088
184	Ubiquitination	AEHRGMLKDNAMLEY HHHCCCCCCCHHHHH	39.79	21906983
188	Sulfoxidation	GMLKDNAMLEYLKIA CCCCCCHHHHHHHHH	3.51	30846556
191	Phosphorylation	KDNAMLEYLKIAQDL CCCHHHHHHHHHHHH	14.88	15647376
191	Ubiquitination	KDNAMLEYLKIAQDL CCCHHHHHHHHHHHH	14.88	24816145
201	Phosphorylation	IAQDLEMYGINYFEI HHHHHHHHCCCEEEE	12.89	-
201	Ubiquitination	IAQDLEMYGINYFEI HHHHHHHHCCCEEEE	12.89	27667366
205	Phosphorylation	LEMYGINYFEIKNKK HHHHCCCEEEEECCC	10.73	-
208	Ubiquitination	YGINYFEIKNKKGTD HCCCEEEEECCCCCC	4.23	21890473
209	Acetylation	GINYFEIKNKKGTDL CCCEEEEECCCCCCE	56.36	25953088
209	Neddylation	GINYFEIKNKKGTDL CCCEEEEECCCCCCE	56.36	32015554
209	Ubiquitination	GINYFEIKNKKGTDL CCCEEEEECCCCCCE	56.36	21906983
211	Ubiquitination	NYFEIKNKKGTDLWL CEEEEECCCCCCEEE	47.80	22817900
212	Ubiquitination	YFEIKNKKGTDLWLG EEEEECCCCCCEEEE	76.16	22817900
221	Ubiquitination	TDLWLGVDALGLNIY CCEEEEECCCCCCCE	33.99	24816145
223	Ubiquitination	LWLGVDALGLNIYEK EEEEECCCCCCCEEC	7.49	23503661
224	Ubiquitination	WLGVDALGLNIYEKD EEEECCCCCCCEECC	20.56	23503661
230	Sumoylation	LGLNIYEKDDKLTPK CCCCCEECCCCCCCC	55.01	-
230	Ubiquitination	LGLNIYEKDDKLTPK CCCCCEECCCCCCCC	55.01	23503661
233	Sumoylation	NIYEKDDKLTPKIGF CCEECCCCCCCCCCC	65.48	-
233	Ubiquitination	NIYEKDDKLTPKIGF CCEECCCCCCCCCCC	65.48	21906983
235	Phosphorylation	YEKDDKLTPKIGFPW EECCCCCCCCCCCCH	28.42	12769842
237	Acetylation	KDDKLTPKIGFPWSE CCCCCCCCCCCCHHH	50.67	25953088
237	Ubiquitination	KDDKLTPKIGFPWSE CCCCCCCCCCCCHHH	50.67	33845483
243	Phosphorylation	PKIGFPWSEIRNISF CCCCCCHHHHCCCCC	24.31	27050516
249	Phosphorylation	WSEIRNISFNDKKFV HHHHCCCCCCCCEEE	22.88	30108239
253	Acetylation	RNISFNDKKFVIKPI CCCCCCCCEEEEEEC	49.57	23749302
253	Malonylation	RNISFNDKKFVIKPI CCCCCCCCEEEEEEC	49.57	26320211
253	Ubiquitination	RNISFNDKKFVIKPI CCCCCCCCEEEEEEC	49.57	23000965
254	Acetylation	NISFNDKKFVIKPID CCCCCCCEEEEEECC	47.96	25953088
254	Malonylation	NISFNDKKFVIKPID CCCCCCCEEEEEECC	47.96	26320211
254	Ubiquitination	NISFNDKKFVIKPID CCCCCCCEEEEEECC	47.96	23000965
258	Acetylation	NDKKFVIKPIDKKAP CCCEEEEEECCCCCC	30.53	23749302
258	Ubiquitination	NDKKFVIKPIDKKAP CCCEEEEEECCCCCC	30.53	23000965
262	Acetylation	FVIKPIDKKAPDFVF EEEEECCCCCCCCEE	52.10	23749302
262	Malonylation	FVIKPIDKKAPDFVF EEEEECCCCCCCCEE	52.10	26320211
262	Sumoylation	FVIKPIDKKAPDFVF EEEEECCCCCCCCEE	52.10	-
262	Ubiquitination	FVIKPIDKKAPDFVF EEEEECCCCCCCCEE	52.10	23000965
263	Acetylation	VIKPIDKKAPDFVFY EEEECCCCCCCCEEE	62.49	19608861
263	Malonylation	VIKPIDKKAPDFVFY EEEECCCCCCCCEEE	62.49	26320211
263	Ubiquitination	VIKPIDKKAPDFVFY EEEECCCCCCCCEEE	62.49	23000965
264	Ubiquitination	IKPIDKKAPDFVFYA EEECCCCCCCCEEEE	18.03	27667366
270	Phosphorylation	KAPDFVFYAPRLRIN CCCCCEEEECCHHCC	15.47	27273156
273	Methylation	DFVFYAPRLRINKRI CCEEEECCHHCCHHH	28.55	-
276	Ubiquitination	FYAPRLRINKRILQL EEECCHHCCHHHHHH	9.37	23503661
291	Phosphorylation	CMGNHELYMRRRKPD HCCCHHHHHCCCCCC	5.89	28442448
291	Ubiquitination	CMGNHELYMRRRKPD HCCCHHHHHCCCCCC	5.89	23503661
296	Acetylation	ELYMRRRKPDTIEVQ HHHHCCCCCCCHHHH	45.49	26051181
296	Malonylation	ELYMRRRKPDTIEVQ HHHHCCCCCCCHHHH	45.49	26320211
296	Ubiquitination	ELYMRRRKPDTIEVQ HHHHCCCCCCCHHHH	45.49	27667366
299	Phosphorylation	MRRRKPDTIEVQQMK HCCCCCCCHHHHHHH	27.80	28985074
302	Ubiquitination	RKPDTIEVQQMKAQA CCCCCHHHHHHHHHH	4.18	23503661
305	Sulfoxidation	DTIEVQQMKAQAREE CCHHHHHHHHHHHHH	1.86	21406390
306	Methylation	TIEVQQMKAQAREEK CHHHHHHHHHHHHHH	32.77	-
306	Ubiquitination	TIEVQQMKAQAREEK CHHHHHHHHHHHHHH	32.77	21906983
314	Ubiquitination	AQAREEKHQKQLERQ HHHHHHHHHHHHHHH	43.26	27667366
316	Ubiquitination	AREEKHQKQLERQQL HHHHHHHHHHHHHHH	57.48	24816145
322	Ubiquitination	QKQLERQQLETEKKR HHHHHHHHHHHHHHH	47.70	27667366
324	Ubiquitination	QLERQQLETEKKRRE HHHHHHHHHHHHHHH	51.05	23503661
325	Phosphorylation	LERQQLETEKKRRET HHHHHHHHHHHHHHH	62.79	27470641
327	Ubiquitination	RQQLETEKKRRETVE HHHHHHHHHHHHHHH	60.03	33845483
332	Phosphorylation	TEKKRRETVEREKEQ HHHHHHHHHHHHHHH	26.34	-
337	Ubiquitination	RETVEREKEQMMREK HHHHHHHHHHHHHHH	60.51	21906983
344	Acetylation	KEQMMREKEELMLRL HHHHHHHHHHHHHHH	46.23	21339330
344	Ubiquitination	KEQMMREKEELMLRL HHHHHHHHHHHHHHH	46.23	21906983
354	Phosphorylation	LMLRLQDYEEKTKKA HHHHHHHHHHHHHHH	17.02	10377409
357	Sumoylation	RLQDYEEKTKKAERE HHHHHHHHHHHHHHH	54.42	-
357	Ubiquitination	RLQDYEEKTKKAERE HHHHHHHHHHHHHHH	54.42	21906983
358	O-linked_Glycosylation	LQDYEEKTKKAEREL HHHHHHHHHHHHHHH	40.85	28510447
358	Phosphorylation	LQDYEEKTKKAEREL HHHHHHHHHHHHHHH	40.85	28152594
359	Ubiquitination	QDYEEKTKKAERELS HHHHHHHHHHHHHHH	62.14	23503661
360	Ubiquitination	DYEEKTKKAERELSE HHHHHHHHHHHHHHH	61.79	23503661
366	Phosphorylation	KKAERELSEQIQRAL HHHHHHHHHHHHHHH	23.78	25159151
387	Ubiquitination	KRAQEEAERLEADRM HHHHHHHHHHHHHHH	62.16	23503661
393	Methylation	AERLEADRMAALRAK HHHHHHHHHHHHHHH	24.56	-
400	Ubiquitination	RMAALRAKEELERQA HHHHHHHHHHHHHHH	45.33	27667366
410	Ubiquitination	LERQAVDQIKSQEQL HHHHHHHHHHCHHHH	38.11	23503661
412	Acetylation	RQAVDQIKSQEQLAA HHHHHHHHCHHHHHH	40.22	21743961
412	Ubiquitination	RQAVDQIKSQEQLAA HHHHHHHHCHHHHHH	40.22	21906983
413	Phosphorylation	QAVDQIKSQEQLAAE HHHHHHHCHHHHHHH	40.35	21945579
424	Nitration	LAAELAEYTAKIALL HHHHHHHHHHHHHHH	13.34	-
424	Phosphorylation	LAAELAEYTAKIALL HHHHHHHHHHHHHHH	13.34	21945579
425	Phosphorylation	AAELAEYTAKIALLE HHHHHHHHHHHHHHH	16.99	21945579
427	Ubiquitination	ELAEYTAKIALLEEA HHHHHHHHHHHHHHH	22.25	21906983
428	Ubiquitination	LAEYTAKIALLEEAR HHHHHHHHHHHHHHH	2.79	24816145
435	Methylation	IALLEEARRRKEDEV HHHHHHHHHCCHHHH	42.06	-
438	Ubiquitination	LEEARRRKEDEVEEW HHHHHHCCHHHHHHH	68.64	21906983
450	Ubiquitination	EEWQHRAKEAQDDLV HHHHHHHHHHHHHHH	54.24	21906983
458	Ubiquitination	EAQDDLVKTKEELHL HHHHHHHCCHHHHEE	62.26	21906983
460	Ubiquitination	QDDLVKTKEELHLVM HHHHHCCHHHHEEEE	43.40	23503661
468	Phosphorylation	EELHLVMTAPPPPPP HHHEEEECCCCCCCC	28.65	-
478	Phosphorylation	PPPPPPVYEPVSYHV CCCCCCCCCCCCHHH	21.93	25884760
482	Phosphorylation	PPVYEPVSYHVQESL CCCCCCCCHHHHHHH	21.89	25884760
483	Phosphorylation	PVYEPVSYHVQESLQ CCCCCCCHHHHHHHH	13.27	25884760
488	Phosphorylation	VSYHVQESLQDEGAE CCHHHHHHHHCCCCC	17.78	26356563
497	Phosphorylation	QDEGAEPTGYSAELS HCCCCCCCCCCEEEC	40.01	26356563
499	Phosphorylation	EGAEPTGYSAELSSE CCCCCCCCCEEECCC	13.74	25884760
523	Acetylation	KRITEAEKNERVQRQ HHHCHHHHHHHHHHH	71.77	25953088
523	Ubiquitination	KRITEAEKNERVQRQ HHHCHHHHHHHHHHH	71.77	21906983
533	Phosphorylation	RVQRQLLTLSSELSQ HHHHHHHHHHHHHHH	32.94	30266825
535	Phosphorylation	QRQLLTLSSELSQAR HHHHHHHHHHHHHHH	19.28	30266825
536	Phosphorylation	RQLLTLSSELSQARD HHHHHHHHHHHHHHH	45.74	30266825
539	Phosphorylation	LTLSSELSQARDENK HHHHHHHHHHHHHCC	20.10	19664994
546	Ubiquitination	SQARDENKRTHNDII HHHHHHCCCCHHHHC	57.54	23503661
548	Phosphorylation	ARDENKRTHNDIIHN HHHHCCCCHHHHCCC	27.00	17855441
558	Sulfoxidation	DIIHNENMRQGRDKY HHCCCHHHHCCHHHH	2.49	21406390
564	Ubiquitination	NMRQGRDKYKTLRQI HHHCCHHHHHHHHHH	47.49	24816145
565	Phosphorylation	MRQGRDKYKTLRQIR HHCCHHHHHHHHHHH	17.31	28796482
567	Phosphorylation	QGRDKYKTLRQIRQG CCHHHHHHHHHHHCC	24.88	22167270
576	Phosphorylation	RQIRQGNTKQRIDEF HHHHCCCHHHCHHHH	35.06	9456324

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
66	S	Phosphorylation	Kinase	PRKACA	P17612	GPS
146	Y	Phosphorylation	Kinase	SRC	P12931	PSP
146	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
146	Y	Phosphorylation	Kinase	FER	P16591	PSP
146	Y	Phosphorylation	Kinase	PDGFR	-	Uniprot
146	Y	Phosphorylation	Kinase	LCK	P06239	PSP
146	Y	Phosphorylation	Kinase	PDGFR-FAMILY	-	GPS
354	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
354	Y	Phosphorylation	Kinase	FER	P16591	PSP
354	Y	Phosphorylation	Kinase	PDGFR	-	Uniprot
354	Y	Phosphorylation	Kinase	PDGFR-FAMILY	-	GPS
478	Y	Phosphorylation	Kinase	SRC	P12931	PSP
478	Y	Phosphorylation	Kinase	SRC	P05480	PSP
478	Y	Phosphorylation	Kinase	FER	P16591	PSP
478	Y	Phosphorylation	Kinase	SRC64	-	PhosphoELM
567	T	Phosphorylation	Kinase	MST4	Q9P289	PSP
567	T	Phosphorylation	Kinase	STK10	O94804	GPS
567	T	Phosphorylation	Kinase	MAP3K8	P41279	GPS
567	T	Phosphorylation	Kinase	ROCK2	O75116	Uniprot
567	T	Phosphorylation	Kinase	ROCK1	Q13464	PSP
567	T	Phosphorylation	Kinase	HGK	O95819	PSP
567	T	Phosphorylation	Kinase	AKT2	P31751	PSP
567	T	Phosphorylation	Kinase	LRRK2	Q5S007	PSP
567	T	Phosphorylation	Kinase	PRKCQ	Q04759	GPS
567	T	Phosphorylation	Kinase	PKCI	P41743	PSP
567	T	Phosphorylation	Kinase	PRKCA	P17252	GPS
567	T	Phosphorylation	Kinase	ARBK1	P25098	PhosphoELM

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of EZRI_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of EZRI_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BID_HUMAN	BID	physical	15659383
TR10B_HUMAN	TNFRSF10B	physical	15659383
FADD_HUMAN	FADD	physical	15659383
TNFL6_HUMAN	FASLG	physical	15659383
MK08_HUMAN	MAPK8	physical	15659383
CASPA_HUMAN	CASP10	physical	15659383
CASP8_HUMAN	CASP8	physical	15659383
TNR1A_HUMAN	TNFRSF1A	physical	15659383
AHNK_HUMAN	AHNAK	physical	14625392
PEPL_HUMAN	PPL	physical	14625392
SPTA1_HUMAN	SPTA1	physical	14625392
PRAX_HUMAN	PRX	physical	14625392
PACE1_HUMAN	SCYL3	physical	12651155
NHRF2_HUMAN	SLC9A3R2	physical	9748260
MERL_HUMAN	NF2	physical	10036239
EZRI_HUMAN	EZR	physical	9501018
FAK1_HUMAN	PTK2	physical	11468295
P85A_HUMAN	PIK3R1	physical	10377409
ICAM1_HUMAN	ICAM1	physical	9705328
ICAM2_HUMAN	ICAM2	physical	9705328
ICAM3_HUMAN	ICAM3	physical	9705328
AA2BR_HUMAN	ADORA2B	physical	12080047
NHRF2_HUMAN	SLC9A3R2	physical	12080047
IQGA1_HUMAN	IQGAP1	physical	10793131
CLIC5_HUMAN	CLIC5	physical	10793131
PALLD_HUMAN	PALLD	physical	11598191
NHRF1_HUMAN	SLC9A3R1	physical	11684085
KPCA_HUMAN	PRKCA	physical	11387207
LYAM3_HUMAN	SELP	physical	10733515
DLG1_HUMAN	DLG1	physical	11726633
TNFL6_HUMAN	FASLG	physical	11013215
SDC2_HUMAN	SDC2	physical	10704377
MOES_HUMAN	MSN	physical	7579708
MERL_HUMAN	NF2	physical	17891137
WWP1_HUMAN	WWP1	physical	22629406
BRCA1_HUMAN	BRCA1	physical	21282464
RADI_HUMAN	RDX	physical	22939629
MPP3_HUMAN	MPP3	physical	21988832
EZRI_HUMAN	EZR	physical	21988832
WFDC1_HUMAN	WFDC1	physical	21988832
ASB6_HUMAN	ASB6	physical	22863883
CROCC_HUMAN	CROCC	physical	22863883
IPO5_HUMAN	IPO5	physical	22863883
MSHR_HUMAN	MC1R	physical	22863883
OGFD1_HUMAN	OGFOD1	physical	22863883
PYGL_HUMAN	PYGL	physical	22863883
RIC8A_HUMAN	RIC8A	physical	22863883
TRNT1_HUMAN	TRNT1	physical	22863883
UB2R2_HUMAN	UBE2R2	physical	22863883
XPP1_HUMAN	XPNPEP1	physical	22863883
VPS11_HUMAN	VPS11	physical	21148287
THIM_HUMAN	ACAA2	physical	26344197
ALDR_HUMAN	AKR1B1	physical	26344197
GDIR1_HUMAN	ARHGDIA	physical	26344197
CALR_HUMAN	CALR	physical	26344197
CLIC4_HUMAN	CLIC4	physical	26344197
IF5A2_HUMAN	EIF5A2	physical	26344197
IF5AL_HUMAN	EIF5AL1	physical	26344197
ENOA_HUMAN	ENO1	physical	26344197
ENOG_HUMAN	ENO2	physical	26344197
FABP5_HUMAN	FABP5	physical	26344197
GPX4_HUMAN	GPX4	physical	26344197
HCD2_HUMAN	HSD17B10	physical	26344197
HSP74_HUMAN	HSPA4	physical	26344197
HS74L_HUMAN	HSPA4L	physical	26344197
CH10_HUMAN	HSPE1	physical	26344197
HS105_HUMAN	HSPH1	physical	26344197
INO1_HUMAN	ISYNA1	physical	26344197
PLSL_HUMAN	LCP1	physical	26344197
OAT_HUMAN	OAT	physical	26344197
PDIA1_HUMAN	P4HB	physical	26344197
PDXK_HUMAN	PDXK	physical	26344197
6PGD_HUMAN	PGD	physical	26344197
PLSI_HUMAN	PLS1	physical	26344197
PLST_HUMAN	PLS3	physical	26344197
IPYR2_HUMAN	PPA2	physical	26344197
RCN1_HUMAN	RCN1	physical	26344197
GLYM_HUMAN	SHMT2	physical	26344197
NHRF1_HUMAN	SLC9A3R1	physical	26344197
STIP1_HUMAN	STIP1	physical	26344197
TAGL2_HUMAN	TAGLN2	physical	26344197
TKT_HUMAN	TKT	physical	26344197
TPD54_HUMAN	TPD52L2	physical	26344197
TRXR2_HUMAN	TXNRD2	physical	26344197
UCHL3_HUMAN	UCHL3	physical	26344197
WDR1_HUMAN	WDR1	physical	26344197
MOES_HUMAN	MSN	physical	26496610
RADI_HUMAN	RDX	physical	26496610
NOLC1_HUMAN	NOLC1	physical	26496610
B4GT7_HUMAN	B4GALT7	physical	26496610
TIM13_HUMAN	TIMM13	physical	26496610
ERBB2_HUMAN	ERBB2	physical	27029001

Drug and Disease Associations

Kegg Disease
H00036	Osteosarcoma
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of EZRI_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-60 AND LYS-139, AND MASSSPECTROMETRY.	19608861 [Abstract]