dbPTM

CHD9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CHD9_HUMAN
UniProt AC	Q3L8U1
Protein Name	Chromodomain-helicase-DNA-binding protein 9
Gene Name	CHD9
Organism	Homo sapiens (Human).
Sequence Length	2897
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity)..
Protein Sequence	MTDPMMDFFDDANLFGETLEGLSDDAFVQPGPVSLVDELNLGAEFEPLHIDSLNHVQGTPTHQKMTDFEQLNQFDSIKFHHVNQSFGSPAEHVLSPHSQFNCSPIHPQNQPNGLFPDVSDGSPMWGHQTATTISNQNGSPFHQQGHSHSMHQNKSFVAHHDFALFQANEQQTQCTSLRSQQNRNNLNPGQNSLSQSKNFMNVSGPHRVNVNHPPQMTNASNSQQSISMQQFSQTSNPSAHFHKCSSHQEGNFNGPSPNMTSCSVSNSQQFSSHYSFSSNHISPNSLLQSSAVLASNHTNQTLSDFTGSNSFSPHRGIKQESTQHILNPNTSLNSNNFQILHSSHPQGNYSNSKLSPVHMNFPDPVDSGTQMGHFNDHVETNGFSSLEENLLHQVESQTEPFTGLDPEDLLQEGLLPHFDESTFGQDNSSHILDHDLDRQFTSHLVTRPSDMAQTQLQSQARSWHSSFSNHQHLHDRNHLCLQRQPPSSKKSDGSGTYTKLQNTQVRVMSEKKQRKKVESESKQEKANRIISEAIAKAKERGERNIPRVMSPENFPTASVEGKEEKKGRRMKSKPKDKDSKKTKTCSKLKEKTKIGKLIITLGKKQKRKNESSDEISDAEQMPQHTLKDQDSQKRRSNRQIKRKKYAEDIEGKQSEEEVKGSMKIKKNSAPLPGEQPLQLFVENPSEEDAAIVDKILSSRTVKKEISPGVMIDTEEFFVKYKNYSYLHCEWATEEQLLKDKRIQQKIKRFKLRQAQRAHFFADMEEEPFNPDYVEVDRVLEVSFCEDKDTGEPVIYYLVKWCSLPYEDSTWELKEDVDLAKIEEFEQLQASRPDTRRLDRPPSNIWKKIDQSRDYKNGNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAPLSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTFEMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEELFSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEETIIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEKILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSGRESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEGRGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRPFSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSHGRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSAPVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYYLKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYNTIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPGDLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQPIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLHKKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVREQALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMAAQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLSTTQDETQDSFQMNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASFYTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGLKLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTLGANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYTQPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEGRPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGVAPEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSGNPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLLSGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPSTSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLGSSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSNED

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTDPMMDFF ------CCCCCHHHC	61.18	-
68	Ubiquitination	THQKMTDFEQLNQFD CCCCCCCHHHHCCCC	4.79	30230243
76	Phosphorylation	EQLNQFDSIKFHHVN HHHCCCCCCEEEECC	29.03	28555341
101	Ubiquitination	LSPHSQFNCSPIHPQ CCCCCCCCCCCCCCC	20.09	30230243
147	Phosphorylation	PFHQQGHSHSMHQNK CCCCCCCCCCCCCCC	24.87	32645325
180	Phosphorylation	QCTSLRSQQNRNNLN HHHHHHHHHHHCCCC	37.83	32645325
192	Phosphorylation	NLNPGQNSLSQSKNF CCCCCCCCCHHCCCC	22.85	28302921
194	Phosphorylation	NPGQNSLSQSKNFMN CCCCCCCHHCCCCCC	32.03	25159151
196	Phosphorylation	GQNSLSQSKNFMNVS CCCCCHHCCCCCCCC	26.62	25627689
197	Sumoylation	QNSLSQSKNFMNVSG CCCCHHCCCCCCCCC	46.71	28112733
197	Ubiquitination	QNSLSQSKNFMNVSG CCCCHHCCCCCCCCC	46.71	29967540
203	Phosphorylation	SKNFMNVSGPHRVNV CCCCCCCCCCCCCCC	41.42	25159151
318	Sumoylation	FSPHRGIKQESTQHI CCCCCCCCHHHCCCC	51.33	-
355	Phosphorylation	NYSNSKLSPVHMNFP CCCCCCCCCCCCCCC	28.72	26074081
421	Phosphorylation	LLPHFDESTFGQDNS CCCCCCCCCCCCCCC	30.77	24275569
490	Acetylation	RQPPSSKKSDGSGTY CCCCCCCCCCCCCCC	56.58	19608861
490 (in isoform 2)	Acetylation	-	56.58	-
491	Phosphorylation	QPPSSKKSDGSGTYT CCCCCCCCCCCCCCE	51.44	20860994
494	Phosphorylation	SSKKSDGSGTYTKLQ CCCCCCCCCCCEEHH	32.71	20860994
496	Phosphorylation	KKSDGSGTYTKLQNT CCCCCCCCCEEHHCC	29.70	30576142
497	Phosphorylation	KSDGSGTYTKLQNTQ CCCCCCCCEEHHCCE	12.85	20049867
499	Acetylation	DGSGTYTKLQNTQVR CCCCCCEEHHCCEEE	37.35	19608861
499	Ubiquitination	DGSGTYTKLQNTQVR CCCCCCEEHHCCEEE	37.35	19608861
499 (in isoform 2)	Acetylation	-	37.35	-
509	Phosphorylation	NTQVRVMSEKKQRKK CCEEEECCHHHHHHH	43.33	24719451
509 (in isoform 2)	Phosphorylation	-	43.33	24719451
521	Phosphorylation	RKKVESESKQEKANR HHHHCCHHHHHHHHH	49.25	-
550	Phosphorylation	RNIPRVMSPENFPTA CCCCCCCCCCCCCCC	26.63	29255136
550 (in isoform 2)	Phosphorylation	-	26.63	27251275
556	Phosphorylation	MSPENFPTASVEGKE CCCCCCCCCCCCCCH	27.68	26657352
558	Phosphorylation	PENFPTASVEGKEEK CCCCCCCCCCCCHHH	24.15	26657352
562	Acetylation	PTASVEGKEEKKGRR CCCCCCCCHHHCCCC	49.55	26051181
575	Ubiquitination	RRMKSKPKDKDSKKT CCCCCCCCCCCCCCC	79.66	30230243
596	Acetylation	KEKTKIGKLIITLGK HHHHHHHHHHHHCCH	39.73	25953088
596	Sumoylation	KEKTKIGKLIITLGK HHHHHHHHHHHHCCH	39.73	28112733
603	Acetylation	KLIITLGKKQKRKNE HHHHHCCHHHCCCCC	55.96	25953088
611	Phosphorylation	KQKRKNESSDEISDA HHCCCCCCCCCCCCH	53.11	29255136
611 (in isoform 2)	Phosphorylation	-	53.11	-
612	Phosphorylation	QKRKNESSDEISDAE HCCCCCCCCCCCCHH	32.84	29255136
612 (in isoform 2)	Phosphorylation	-	32.84	-
616	Phosphorylation	NESSDEISDAEQMPQ CCCCCCCCCHHHCCH	28.81	29255136
616 (in isoform 2)	Phosphorylation	-	28.81	-
625	Phosphorylation	AEQMPQHTLKDQDSQ HHHCCHHHCCCHHHH	30.20	18669648
625 (in isoform 2)	Phosphorylation	-	30.20	-
654	Phosphorylation	EDIEGKQSEEEVKGS HHCCCCCCHHHHHHC	50.92	29255136
654 (in isoform 2)	Phosphorylation	-	50.92	24719451
661	Phosphorylation	SEEEVKGSMKIKKNS CHHHHHHCCCCCCCC	15.93	28857561
694	Ubiquitination	EDAAIVDKILSSRTV HHHHHHHHHHCCCCC	34.35	29967540
697	Phosphorylation	AIVDKILSSRTVKKE HHHHHHHCCCCCCCE	22.65	24719451
698	Phosphorylation	IVDKILSSRTVKKEI HHHHHHCCCCCCCEE	28.64	24719451
698 (in isoform 2)	Phosphorylation	-	28.64	24719451
703	Ubiquitination	LSSRTVKKEISPGVM HCCCCCCCEECCCCE	56.81	29967540
720	Phosphorylation	TEEFFVKYKNYSYLH CHHEEEEECCCEEEE	10.12	-
725	Phosphorylation	VKYKNYSYLHCEWAT EEECCCEEEECEECC	7.07	-
738	"N6,N6-dimethyllysine"	ATEEQLLKDKRIQQK CCHHHHHHCHHHHHH	70.56	-
738	Methylation	ATEEQLLKDKRIQQK CCHHHHHHCHHHHHH	70.56	23644510
772	Phosphorylation	EEPFNPDYVEVDRVL CCCCCCCCEEEEEEE	10.36	-
782	Phosphorylation	VDRVLEVSFCEDKDT EEEEEEEEEEECCCC	18.14	21815630
820	Ubiquitination	KEDVDLAKIEEFEQL CCCCCHHHHHHHHHH	58.93	29967540
846	Ubiquitination	RPPSNIWKKIDQSRD CCCCHHHHHHHCCCC	35.73	29967540
892	Phosphorylation	DEMGLGKTIQSITFL CCCCCCHHHHHHHHH	23.58	24275569
896	Ubiquitination	LGKTIQSITFLYEIL CCHHHHHHHHHHHHH	1.48	32142685
929	Ubiquitination	NWEREFRTWTDINVV CHHHHHCCCCCCEEE	37.73	32142685
938	Phosphorylation	TDINVVVYHGSLISR CCCEEEEEECHHHHH	6.72	26307563
941	Phosphorylation	NVVVYHGSLISRQMI EEEEEECHHHHHHHH	14.82	24719451
944	Phosphorylation	VYHGSLISRQMIQQY EEECHHHHHHHHHHH	23.04	24719451
951	Phosphorylation	SRQMIQQYEMYFRDS HHHHHHHHHHHEECC	6.06	-
1008	Ubiquitination	RLKNKNCKLLEGLKL HHCCCCCCHHHHHHH	66.55	-
1014	Ubiquitination	CKLLEGLKLMNLEHK CCHHHHHHHCCCCCE	57.45	29967540
1069	Ubiquitination	KTEEQVQKLQAILKP CCHHHHHHHHHHHHH	43.65	29967540
1075	Ubiquitination	QKLQAILKPMMLRRL HHHHHHHHHHHHHHH	25.42	-
1109	Phosphorylation	LTNIQKKYYRAILEK EHHHHHHHHHHHHHH	12.76	-
1110	Phosphorylation	TNIQKKYYRAILEKN HHHHHHHHHHHHHHC	11.49	-
1116	Acetylation	YYRAILEKNFSFLSK HHHHHHHHCCCHHHC	60.90	26051181
1116	Ubiquitination	YYRAILEKNFSFLSK HHHHHHHHCCCHHHC	60.90	-
1119	Phosphorylation	AILEKNFSFLSKGAG HHHHHCCCHHHCCCC	34.37	23312004
1128	Phosphorylation	LSKGAGQTNVPNLVN HHCCCCCCCCCHHHH	36.95	23898821
1136	Phosphorylation	NVPNLVNTMMELRKC CCCHHHHHHHHHHHH	15.49	23898821
1151	Ubiquitination	CNHPYLIKGAEEKIL CCCCHHHCCHHHHHH	49.85	29967540
1156	Ubiquitination	LIKGAEEKILGEFRD HHCCHHHHHHHHHHH	34.43	29967540
1189	Ubiquitination	GKLVLIDKLLPKMKA CEEEEHHHHHHHHCC	44.95	-
1207	Sulfoxidation	KVLIFSQMVRCLDIL EEEEEHHHHHHHHHH	1.67	31801345
1251	Methylation	FSKPDSDRFVFLLCT HCCCCHHCEEEEEEC	33.31	-
1323	Ubiquitination	MFDRASLKLGLDKAV CHHHHHHHHCCCHHH	37.70	29967540
1328	Ubiquitination	SLKLGLDKAVLQSMS HHHHCCCHHHHHHHC	45.50	-
1333	Phosphorylation	LDKAVLQSMSGRESN CCHHHHHHHCCCCCC	15.68	24719451
1333 (in isoform 2)	Phosphorylation	-	15.68	24719451
1335	Phosphorylation	KAVLQSMSGRESNVG HHHHHHHCCCCCCCC	39.69	28348404
1335 (in isoform 2)	Phosphorylation	-	39.69	27251275
1349	Ubiquitination	GGIQQLSKKEIEDLL CHHHHCCHHHHHHHH	64.12	29967540
1350	Ubiquitination	GIQQLSKKEIEDLLR HHHHCCHHHHHHHHH	61.62	29967540
1387	Phosphorylation	DQILLRRTKTITIES HHHHHHCCCEEEEEE	26.55	-
1389	Phosphorylation	ILLRRTKTITIESEG HHHHCCCEEEEEECC	23.80	-
1403	Ubiquitination	GRGSTFAKASFVASG CCCCCEEEEEEEECC	40.13	32142685
1405	Phosphorylation	GSTFAKASFVASGNR CCCEEEEEEEECCCC	21.39	-
1425	Ubiquitination	DDPNFWQKWAKKAEI CCCCHHHHHHHHCCC	39.45	-
1429	Sumoylation	FWQKWAKKAEIDIEA HHHHHHHHCCCEEEE	43.43	-
1429	Sumoylation	FWQKWAKKAEIDIEA HHHHHHHHCCCEEEE	43.43	-
1429	Ubiquitination	FWQKWAKKAEIDIEA HHHHHHHHCCCEEEE	43.43	29967540
1438	Phosphorylation	EIDIEAISGRNSLVI CCEEEECCCCCCEEE	38.45	20860994
1447	Phosphorylation	RNSLVIDTPRIRKQT CCCEEEECHHHHCCC	11.89	21815630
1454	Phosphorylation	TPRIRKQTRPFSATK CHHHHCCCCCCCCCH	43.26	23186163
1458	Phosphorylation	RKQTRPFSATKDELA HCCCCCCCCCHHHHH	37.40	25159151
1460	Phosphorylation	QTRPFSATKDELAEL CCCCCCCCHHHHHHH	37.52	23186163
1468	Phosphorylation	KDELAELSEAESEGD HHHHHHHHHHHHCCC	26.68	29255136
1468 (in isoform 2)	Phosphorylation	-	26.68	27251275
1472	Phosphorylation	AELSEAESEGDEKPK HHHHHHHHCCCCCCC	54.66	29255136
1472 (in isoform 2)	Phosphorylation	-	54.66	27251275
1493	O-linked_Glycosylation	RSNGYGRTECFRVEK CCCCCCCCCEEEEEC	32.51	30379171
1519	Phosphorylation	EILSHGRFKRQLNEH HHHHCCCHHHHCCHH	10.15	32142685
1552	Phosphorylation	GDEKIKGFIWDLITP CCCCCCEEEEECCCC	4.30	32142685
1585	Phosphorylation	VPRGRKGKKVKTQTS CCCCCCCCCCCCCCC	58.38	33259812
1588	Sumoylation	GRKGKKVKTQTSSFD CCCCCCCCCCCCCCC	43.74	28112733
1598	Ubiquitination	TSSFDIQKAEWLRKY CCCCCHHHHHHHHHH	48.91	29967540
1604	Ubiquitination	QKAEWLRKYNPEQLL HHHHHHHHHCHHHHH	47.40	29967540
1616	Phosphorylation	QLLQDEGYKKHIKHH HHHCCCHHHHHHHHH	18.15	27067055
1635	Phosphorylation	LLRVRMLYYLKQEVI HHHHHHHHHHHHHHH	9.45	21406692
1636	Phosphorylation	LRVRMLYYLKQEVIG HHHHHHHHHHHHHHC	11.94	21406692
1682	Phosphorylation	WDFDADKSLLIGVFK CCCCCCHHHEEEHHH	29.02	20068231
1692	Phosphorylation	IGVFKHGYEKYNTIR EEHHHCCHHHHCCCC	14.68	-
1694	Ubiquitination	VFKHGYEKYNTIRAD HHHCCHHHHCCCCCC	35.00	29967540
1695	Phosphorylation	FKHGYEKYNTIRADP HHCCHHHHCCCCCCH	12.95	-
1716	Ubiquitination	RVGKPDEKAVAAEQR ECCCCCHHHHHHHHH	56.38	29967540
1738	Sumoylation	DVEDPEYKPAPAIFK CCCCCCCCCCCCCCC	32.80	28112733
1753	Phosphorylation	DDIEDDVSSPGDLVI CCCCCCCCCCCCEEE	37.50	25850435
1754	Phosphorylation	DIEDDVSSPGDLVIA CCCCCCCCCCCEEEE	32.52	30576142
1774	Phosphorylation	LMEGDKVYWPTQSAL EECCCEEECCCHHHH	16.06	20068231
1777	Phosphorylation	GDKVYWPTQSALTTR CCEEECCCHHHHHHH	22.47	20068231
1777 (in isoform 2)	Phosphorylation	-	22.47	-
1779	Phosphorylation	KVYWPTQSALTTRLR EEECCCHHHHHHHHH	27.94	20068231
1782	Phosphorylation	WPTQSALTTRLRRLI CCCHHHHHHHHHHHH	15.02	20068231
1902	Phosphorylation	RRVCRLPSKEELVDP HHHHCCCCCHHHCCC	58.24	24719451
1902 (in isoform 2)	Phosphorylation	-	58.24	24719451
1903	Sumoylation	RVCRLPSKEELVDPN HHHCCCCCHHHCCCC	53.95	28112733
2009	Phosphorylation	SQSKMAHSRTSTPLL CHHHHCCCCCCCHHH	27.93	24719451
2011	Phosphorylation	SKMAHSRTSTPLLQQ HHHCCCCCCCHHHHH	39.71	22199227
2011 (in isoform 2)	Phosphorylation	-	39.71	27251275
2012	Phosphorylation	KMAHSRTSTPLLQQY HHCCCCCCCHHHHHH	27.24	22199227
2012 (in isoform 2)	Phosphorylation	-	27.24	24719451
2013	Phosphorylation	MAHSRTSTPLLQQYQ HCCCCCCCHHHHHHH	19.83	22199227
2013 (in isoform 2)	Phosphorylation	-	19.83	27251275
2019	Phosphorylation	STPLLQQYQVALSAS CCHHHHHHHHHHCCC	7.62	27732954
2024	Phosphorylation	QQYQVALSASPLTSL HHHHHHHCCCCCCCH	19.57	22199227
2024 (in isoform 2)	Phosphorylation	-	19.57	27251275
2026	Phosphorylation	YQVALSASPLTSLPR HHHHHCCCCCCCHHH	19.64	21712546
2026 (in isoform 2)	Phosphorylation	-	19.64	24719451
2029	Phosphorylation	ALSASPLTSLPRLLD HHCCCCCCCHHHHHC	31.44	22199227
2030	Phosphorylation	LSASPLTSLPRLLDA HCCCCCCCHHHHHCC	44.02	27732954
2038	Sumoylation	LPRLLDAKGIILEEM HHHHHCCCCCEEEEE	50.76	-
2038	Sumoylation	LPRLLDAKGIILEEM HHHHHCCCCCEEEEE	50.76	28112733
2038	Ubiquitination	LPRLLDAKGIILEEM HHHHHCCCCCEEEEE	50.76	-
2049	Phosphorylation	LEEMKVKSENLKEEP EEEECCCCCCCCCCC	34.40	25137130
2058	Phosphorylation	NLKEEPQSSEEESMS CCCCCCCCCHHHHHH	50.89	30278072
2058 (in isoform 2)	Phosphorylation	-	50.89	24719451
2059	Phosphorylation	LKEEPQSSEEESMSS CCCCCCCCHHHHHHC	43.72	30278072
2059 (in isoform 2)	Phosphorylation	-	43.72	24719451
2063	Phosphorylation	PQSSEEESMSSVETR CCCCHHHHHHCHHHH	27.52	23927012
2065	Phosphorylation	SSEEESMSSVETRTL CCHHHHHHCHHHHHH	40.28	29978859
2066	Phosphorylation	SEEESMSSVETRTLI CHHHHHHCHHHHHHH	18.48	29978859
2069	Phosphorylation	ESMSSVETRTLIKSE HHHHCHHHHHHHCCC	27.14	29978859
2071	Phosphorylation	MSSVETRTLIKSEPV HHCHHHHHHHCCCCC	40.01	23403867
2074	Sumoylation	VETRTLIKSEPVSPK HHHHHHHCCCCCCCC	52.45	-
2074	Sumoylation	VETRTLIKSEPVSPK HHHHHHHCCCCCCCC	52.45	28112733
2075	Phosphorylation	ETRTLIKSEPVSPKN HHHHHHCCCCCCCCC	39.89	23401153
2075 (in isoform 2)	Phosphorylation	-	39.89	27251275
2079	Phosphorylation	LIKSEPVSPKNGVLP HHCCCCCCCCCCCCC	40.65	23401153
2079 (in isoform 2)	Phosphorylation	-	40.65	24719451
2094	Phosphorylation	QATGDQKSGGKCETD CCCCCCCCCCCCCHH	47.33	18452278
2094 (in isoform 2)	Phosphorylation	-	47.33	-
2109	Phosphorylation	RRMVAARTEPLTPNP HCHHHCCCCCCCCCC	36.91	29255136
2113	Phosphorylation	AARTEPLTPNPASKK HCCCCCCCCCCCCCC	31.56	26657352
2113 (in isoform 2)	Phosphorylation	-	31.56	24719451
2118	Phosphorylation	PLTPNPASKKPRVHK CCCCCCCCCCCCCCC	42.33	29255136
2119	Acetylation	LTPNPASKKPRVHKR CCCCCCCCCCCCCCC	69.75	25953088
2138	Phosphorylation	SSDSDSDSERSSCSS CCCCCCCCCCCCCCC	38.57	-
2141	Phosphorylation	SDSDSERSSCSSRSS CCCCCCCCCCCCCCC	31.48	-
2142	Phosphorylation	DSDSERSSCSSRSSS CCCCCCCCCCCCCCC	25.00	-
2149	Phosphorylation	SCSSRSSSSSSSSSC CCCCCCCCCCCCCCC	35.17	-
2150	Phosphorylation	CSSRSSSSSSSSSCS CCCCCCCCCCCCCCC	35.87	-
2151	Phosphorylation	SSRSSSSSSSSSCSH CCCCCCCCCCCCCCC	35.87	-
2152	Phosphorylation	SRSSSSSSSSSCSHS CCCCCCCCCCCCCCC	35.87	-
2154	Phosphorylation	SSSSSSSSSCSHSRS CCCCCCCCCCCCCCC	36.99	-
2157	Phosphorylation	SSSSSSCSHSRSGSS CCCCCCCCCCCCCCC	26.84	-
2159	Phosphorylation	SSSSCSHSRSGSSSS CCCCCCCCCCCCCCC	16.31	-
2185	Phosphorylation	SSSSTSSSSSSSSSS CCCCCCCCCCCCCCC	33.72	-
2186	Phosphorylation	SSSTSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
2187	Phosphorylation	SSTSSSSSSSSSSSE CCCCCCCCCCCCCCC	35.87	-
2188	Phosphorylation	STSSSSSSSSSSSEE CCCCCCCCCCCCCCC	35.87	-
2189	Phosphorylation	TSSSSSSSSSSSEES CCCCCCCCCCCCCCC	35.87	-
2198	Phosphorylation	SSSEESDSDEEEAQK CCCCCCCCHHHHHHH	57.09	-
2279	Acetylation	CQTVLKGKWPSARRS HHHHHCCCCCCCCCC	55.11	26051181
2286	Phosphorylation	KWPSARRSYDANTVA CCCCCCCCCCCCHHH	23.08	25159151
2286 (in isoform 2)	Phosphorylation	-	23.08	27251275
2287	Phosphorylation	WPSARRSYDANTVAS CCCCCCCCCCCHHHH	19.77	29214152
2287 (in isoform 2)	Phosphorylation	-	19.77	27251275
2303	Phosphorylation	YTTKLLDSPGAATEY HHHCCCCCCCCCCCC	25.79	20873877
2303 (in isoform 2)	Phosphorylation	-	25.79	27251275
2308	Phosphorylation	LDSPGAATEYSDPSV CCCCCCCCCCCCCCC	34.62	27732954
2330	Phosphorylation	VKEEHDQSTQMSKVK CCCCCCCHHCHHHHH	27.02	29449344
2331	Phosphorylation	KEEHDQSTQMSKVKK CCCCCCHHCHHHHHH	23.74	29449344
2334	Phosphorylation	HDQSTQMSKVKKHVR CCCHHCHHHHHHHHH	25.20	29449344
2348	Sumoylation	REKEFTVKIKDEGGL HHCEEEEEEECCCCE	40.77	-
2350	Sumoylation	KEFTVKIKDEGGLKL CEEEEEEECCCCEEE	43.97	-
2350	Sumoylation	KEFTVKIKDEGGLKL CEEEEEEECCCCEEE	43.97	28112733
2351	Ubiquitination	EFTVKIKDEGGLKLT EEEEEEECCCCEEEE	64.35	29967540
2356	Sumoylation	IKDEGGLKLTFQKQG EECCCCEEEEEEECC	49.07	28112733
2361	Sumoylation	GLKLTFQKQGLAQKR CEEEEEEECCCCCCC	41.99	28112733
2361	Ubiquitination	GLKLTFQKQGLAQKR CEEEEEEECCCCCCC	41.99	-
2367	Ubiquitination	QKQGLAQKRPFDGED EECCCCCCCCCCCCC	57.33	-
2396	Phosphorylation	LQSASETSLVNFPKS HHCCCCCCCCCCCCC	26.69	28555341
2554	Phosphorylation	PNKLDVNSLTGEERV CCCCCHHHCCHHHHH	27.44	22496350
2572	Ubiquitination	NRRNARKVGGAFAPP HHCCCCCCCCCCCCC	7.72	29967540
2588	Ubiquitination	KDLCRFLKENSEYGV HHHHHHHHHCCCCCC	52.73	-
2606	Phosphorylation	WGDVVKQSGFLPESM HHHHHHHCCCCCHHH	26.29	28348404
2612	Phosphorylation	QSGFLPESMYERILT HCCCCCHHHHHHHHH	25.40	28348404
2737	Phosphorylation	LLTKPTESGTEDKKG CCCCCCCCCCCCCCC	54.19	-
2838	Acetylation	NSDLGSSKSVEVKEE CCCCCCCCCEEECHH	61.28	26051181
2843	Sumoylation	SSKSVEVKEEDSRIK CCCCEEECHHHHCCC	41.71	-
2843	Sumoylation	SSKSVEVKEEDSRIK CCCCEEECHHHHCCC	41.71	28112733
2858	Phosphorylation	DQEDKGGTEPSPLNE CCCCCCCCCCCCCCC	54.08	30177828
2861	Phosphorylation	DKGGTEPSPLNENST CCCCCCCCCCCCCCC	35.47	25159151
2867	Phosphorylation	PSPLNENSTDEGSEK CCCCCCCCCCCCCCC	30.93	29255136
2868	Phosphorylation	SPLNENSTDEGSEKA CCCCCCCCCCCCCCC	50.04	29255136
2872	Phosphorylation	ENSTDEGSEKADASS CCCCCCCCCCCCCCC	33.60	29255136
2879	Phosphorylation	SEKADASSGSDSTSS CCCCCCCCCCCCCCC	44.00	18220336
2883	Phosphorylation	DASSGSDSTSSSSED CCCCCCCCCCCCCCC	31.70	30576142
2887	Phosphorylation	GSDSTSSSSEDSDSS CCCCCCCCCCCCCCC	37.20	30576142
2891	Phosphorylation	TSSSSEDSDSSNED- CCCCCCCCCCCCCC-	35.03	18220336
2893	Phosphorylation	SSSEDSDSSNED--- CCCCCCCCCCCC---	38.73	30576142
2894	Phosphorylation	SSEDSDSSNED---- CCCCCCCCCCC----	49.59	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CHD9_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CHD9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CHD9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CHD9_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CHD9_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-499, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-550; SER-1468; SER-1472;SER-2058; SER-2059; SER-2075 AND SER-2079, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1468 AND SER-1472, ANDMASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-550; SER-611; SER-612;THR-625; THR-2013 AND SER-2026, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-550, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2879; SER-2883 ANDSER-2891, AND MASS SPECTROMETRY.	18220336 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-611; SER-612; SER-616;SER-1468 AND SER-1472, AND MASS SPECTROMETRY.	17081983 [Abstract]