NCOR2_HUMAN - dbPTM
NCOR2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NCOR2_HUMAN
UniProt AC Q9Y618
Protein Name Nuclear receptor corepressor 2
Gene Name NCOR2
Organism Homo sapiens (Human).
Sequence Length 2525
Subcellular Localization Nucleus.
Protein Description Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival..
Protein Sequence MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREELRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHTLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSGSTQPVA
------CCCCCCCCC
53.4022199227
4Phosphorylation----MSGSTQPVAQT
----CCCCCCCCCCC
32.9122199227
5Phosphorylation---MSGSTQPVAQTW
---CCCCCCCCCCCC
40.1822199227
11PhosphorylationSTQPVAQTWRATEPR
CCCCCCCCCCCCCCC
13.7429759185
18Asymmetric dimethylarginineTWRATEPRYPPHSLS
CCCCCCCCCCCCCCC
50.81-
18MethylationTWRATEPRYPPHSLS
CCCCCCCCCCCCCCC
50.81-
19PhosphorylationWRATEPRYPPHSLSY
CCCCCCCCCCCCCCC
31.6522985185
23O-linked_GlycosylationEPRYPPHSLSYPVQI
CCCCCCCCCCCCEEE
25.4530059200
25O-linked_GlycosylationRYPPHSLSYPVQIAR
CCCCCCCCCCEEEEE
30.3330059200
35PhosphorylationVQIARTHTDVGLLEY
EEEEECCCCCCCEEE
31.5928555341
42PhosphorylationTDVGLLEYQHHSRDY
CCCCCEEECCCCCCC
17.0827642862
49PhosphorylationYQHHSRDYASHLSPG
ECCCCCCCHHHCCCC
14.6423403867
51PhosphorylationHHSRDYASHLSPGSI
CCCCCCHHHCCCCCC
20.8023401153
54PhosphorylationRDYASHLSPGSIIQP
CCCHHHCCCCCCCCC
23.0723401153
54 (in isoform 5)Phosphorylation-23.07-
57PhosphorylationASHLSPGSIIQPQRR
HHHCCCCCCCCCCCC
21.6523401153
67PhosphorylationQPQRRRPSLLSEFQP
CCCCCCHHHHCCCCC
39.8823401153
67 (in isoform 5)Phosphorylation-39.88-
70PhosphorylationRRRPSLLSEFQPGNE
CCCHHHHCCCCCCCC
41.4823898821
79PhosphorylationFQPGNERSQELHLRP
CCCCCCCCCCEECCC
23.10-
88PhosphorylationELHLRPESHSYLPEL
CEECCCCCCCCCCCC
22.0328555341
98PhosphorylationYLPELGKSEMEFIES
CCCCCCHHHHHHHHC
40.1428270605
105PhosphorylationSEMEFIESKRPRLEL
HHHHHHHCCCCCHHH
29.2028270605
106UbiquitinationEMEFIESKRPRLELL
HHHHHHCCCCCHHHC
54.34-
121PhosphorylationPDPLLRPSPLLATGQ
CCCCCCCCCCCCCCC
23.0329255136
126PhosphorylationRPSPLLATGQPAGSE
CCCCCCCCCCCCCCC
36.0029255136
132PhosphorylationATGQPAGSEDLTKDR
CCCCCCCCCCCCCCC
30.0028122231
136PhosphorylationPAGSEDLTKDRSLTG
CCCCCCCCCCCCCCC
43.1328122231
137UbiquitinationAGSEDLTKDRSLTGK
CCCCCCCCCCCCCCC
59.44-
140PhosphorylationEDLTKDRSLTGKLEP
CCCCCCCCCCCCCEE
40.1823927012
142PhosphorylationLTKDRSLTGKLEPVS
CCCCCCCCCCCEECC
33.2528464451
149PhosphorylationTGKLEPVSPPSPPHT
CCCCEECCCCCCCCC
41.6329255136
149 (in isoform 5)Phosphorylation-41.63-
152PhosphorylationLEPVSPPSPPHTDPE
CEECCCCCCCCCCCC
55.2229255136
152 (in isoform 5)Phosphorylation-55.22-
156PhosphorylationSPPSPPHTDPELELV
CCCCCCCCCCCCCCC
60.0529255136
156 (in isoform 5)Phosphorylation-60.05-
185SulfoxidationRVDREITMVEQQISK
HHHHHHHHHHHHHHH
3.7121406390
215PhosphorylationPEPEKPVSPPPIESK
CCCCCCCCCCCCCCH
39.9729255136
215 (in isoform 5)Phosphorylation-39.97-
221PhosphorylationVSPPPIESKHRSLVQ
CCCCCCCCHHHHHHH
34.1922167270
221 (in isoform 5)Phosphorylation-34.19-
225PhosphorylationPIESKHRSLVQIIYD
CCCCHHHHHHHHHEE
32.3926074081
231PhosphorylationRSLVQIIYDENRKKA
HHHHHHHEECCHHHH
20.8726074081
271UbiquitinationRQYHENIKINQAMRK
HHHHHHCCCCHHHHH
47.38-
332PhosphorylationKESKVREYYEKQFPE
HHHHHHHHHHHHCHH
13.32-
333PhosphorylationESKVREYYEKQFPEI
HHHHHHHHHHHCHHH
16.34-
335UbiquitinationKVREYYEKQFPEIRK
HHHHHHHHHCHHHHH
40.91-
359PhosphorylationSRVGQRGSGLSMSAA
HHHHHCCCCCCHHHH
38.4628555341
373PhosphorylationARSEHEVSEIIDGLS
HHCHHHHHHHHHCCH
21.79-
380PhosphorylationSEIIDGLSEQENLEK
HHHHHCCHHHHHHHH
42.64-
433PhosphorylationRQVMNMWSEQEKETF
HHHHHCCCHHHHHHH
20.7330619164
479PhosphorylationLTKKNENYKSLVRRS
HHCCCCCHHHHHHHH
8.8623403867
481PhosphorylationKKNENYKSLVRRSYR
CCCCCHHHHHHHHHH
23.0323403867
493PhosphorylationSYRRRGKSQQQQQQQ
HHHHHCHHHHHHHHH
35.7328985074
515PhosphorylationQQQPMPRSSQEEKDE
HHCCCCCCHHHHHHH
30.4222199227
516PhosphorylationQQPMPRSSQEEKDEK
HCCCCCCHHHHHHHH
42.7822199227
550PhosphorylationEDLLKEKTDDTSGED
HHHHHHHCCCCCCCC
39.9522167270
550 (in isoform 5)Phosphorylation-39.95-
552PhosphorylationLLKEKTDDTSGEDND
HHHHHCCCCCCCCCH
48.2624719451
553PhosphorylationLKEKTDDTSGEDNDE
HHHHCCCCCCCCCHH
41.2522167270
553 (in isoform 5)Phosphorylation-41.25-
554PhosphorylationKEKTDDTSGEDNDEK
HHHCCCCCCCCCHHH
47.3722167270
554 (in isoform 5)Phosphorylation-47.37-
566PhosphorylationDEKEAVASKGRKTAN
HHHHHHHHHCCCCCC
29.1020873877
585PhosphorylationRKGRITRSMANEANS
HHCHHHHHHHHHCCC
17.3825599653
592PhosphorylationSMANEANSEEAITPQ
HHHHHCCCCCCCCHH
43.8125599653
597PhosphorylationANSEEAITPQQSAEL
CCCCCCCCHHHHHHH
23.3025599653
601PhosphorylationEAITPQQSAELASME
CCCCHHHHHHHHHCC
20.6125599653
612PhosphorylationASMELNESSRWTEEE
HHCCCCHHHCCCHHH
24.9125599653
616PhosphorylationLNESSRWTEEEMETA
CCHHHCCCHHHHHHH
32.2023322592
672SumoylationILQQHKLKMEKERNA
HHHHHHHHHHHHHHH
50.22-
672SumoylationILQQHKLKMEKERNA
HHHHHHHHHHHHHHH
50.2217000644
672 (in isoform 5)Sumoylation-50.22-
708PhosphorylationEDEEMEASGVSGNEE
CCHHHHHCCCCCCHH
26.8225921289
711PhosphorylationEMEASGVSGNEEEMV
HHHHCCCCCCHHHHH
39.1525921289
737PhosphorylationEVPRGECSGPATVNN
CCCCCCCCCCCCCCC
43.4323663014
741PhosphorylationGECSGPATVNNSSDT
CCCCCCCCCCCCCCC
27.2230278072
745PhosphorylationGPATVNNSSDTESIP
CCCCCCCCCCCCCCC
25.1221712546
746PhosphorylationPATVNNSSDTESIPS
CCCCCCCCCCCCCCC
51.1530278072
748PhosphorylationTVNNSSDTESIPSPH
CCCCCCCCCCCCCCC
33.3127362937
750PhosphorylationNNSSDTESIPSPHTE
CCCCCCCCCCCCCCH
41.7230278072
753PhosphorylationSDTESIPSPHTEAAK
CCCCCCCCCCCHHHH
27.8730278072
756PhosphorylationESIPSPHTEAAKDTG
CCCCCCCCHHHHHCC
30.6122617229
784PhosphorylationGPPPGPPTPPPEDIP
CCCCCCCCCCCCCCC
52.1125921289
803PhosphorylationPTPASEATGAPTPPP
CCCHHHCCCCCCCCC
29.8026074081
807PhosphorylationSEATGAPTPPPAPPS
HHCCCCCCCCCCCCC
48.1426074081
814PhosphorylationTPPPAPPSPSAPPPV
CCCCCCCCCCCCCCC
30.3526074081
816PhosphorylationPPAPPSPSAPPPVVP
CCCCCCCCCCCCCCC
58.7226074081
844SumoylationVEEGEEQKPPAAEEL
CCCCCCCCCCHHHHH
57.14-
846 (in isoform 5)Sumoylation-51.65-
857AcetylationELAVDTGKAEEPVKS
HHCCCCCCCCCCCCC
55.5126051181
861 (in isoform 5)Acetylation-30.27-
863SumoylationGKAEEPVKSECTEEA
CCCCCCCCCCCCHHH
51.78-
863SumoylationGKAEEPVKSECTEEA
CCCCCCCCCCCCHHH
51.7817000644
864PhosphorylationKAEEPVKSECTEEAE
CCCCCCCCCCCHHHH
37.8321082442
867PhosphorylationEPVKSECTEEAEEGP
CCCCCCCCHHHHCCC
32.5828985074
875 (in isoform 5)Sumoylation-44.05-
878AcetylationEEGPAKGKDAEAAEA
HCCCCCCCCHHHHHH
53.7319608861
892SumoylationATAEGALKAEKKEGG
HHHHHHHHHHHCCCC
54.70-
892SumoylationATAEGALKAEKKEGG
HHHHHHHHHHHCCCC
54.7017000644
897PhosphorylationALKAEKKEGGSGRAT
HHHHHHCCCCCCCCC
78.7424719451
899PhosphorylationKAEKKEGGSGRATTA
HHHHCCCCCCCCCCC
28.1924719451
900PhosphorylationAEKKEGGSGRATTAK
HHHCCCCCCCCCCCC
35.6424719451
904PhosphorylationEGGSGRATTAKSSGA
CCCCCCCCCCCCCCC
26.4024719451
905 (in isoform 5)Phosphorylation-30.97-
908PhosphorylationGRATTAKSSGAPQDS
CCCCCCCCCCCCCCC
31.3829632367
909PhosphorylationRATTAKSSGAPQDSD
CCCCCCCCCCCCCCC
37.9629632367
915PhosphorylationSSGAPQDSDSSATCS
CCCCCCCCCCCCCCC
33.8629632367
917PhosphorylationGAPQDSDSSATCSAD
CCCCCCCCCCCCCHH
26.3123663014
918PhosphorylationAPQDSDSSATCSADE
CCCCCCCCCCCCHHH
32.3730278072
920PhosphorylationQDSDSSATCSADEVD
CCCCCCCCCCHHHHH
14.6730278072
921PhosphorylationDSDSSATCSADEVDE
CCCCCCCCCHHHHHH
2.9324719451
922PhosphorylationSDSSATCSADEVDEA
CCCCCCCCHHHHHHC
34.1130278072
922 (in isoform 5)Phosphorylation-34.11-
926 (in isoform 5)Phosphorylation-9.19-
928PhosphorylationCSADEVDEAEGGDKN
CCHHHHHHCCCCCCC
54.5224719451
929 (in isoform 5)Phosphorylation-19.10-
938PhosphorylationGGDKNRLLSPRPSLL
CCCCCCCCCCCCCCC
6.3024719451
939PhosphorylationGDKNRLLSPRPSLLT
CCCCCCCCCCCCCCC
24.3729255136
939 (in isoform 5)Phosphorylation-24.37-
942 (in isoform 5)Acetylation-32.48-
943PhosphorylationRLLSPRPSLLTPTGD
CCCCCCCCCCCCCCC
36.9729255136
946PhosphorylationSPRPSLLTPTGDPRA
CCCCCCCCCCCCCCC
24.8929255136
948PhosphorylationRPSLLTPTGDPRANA
CCCCCCCCCCCCCCC
49.3230266825
956PhosphorylationGDPRANASPQKPLDL
CCCCCCCCCCCCCCH
27.8929255136
959AcetylationRANASPQKPLDLKQL
CCCCCCCCCCCHHHH
51.4319608861
964AcetylationPQKPLDLKQLKQRAA
CCCCCCHHHHHHHHH
53.9326051181
979PhosphorylationAIPPIQVTKVHEPPR
CCCCCEEEECCCCCC
15.80-
992PhosphorylationPREDAAPTKPAPPAP
CCCCCCCCCCCCCCC
44.9523927012
992 (in isoform 5)Phosphorylation-44.95-
993AcetylationREDAAPTKPAPPAPP
CCCCCCCCCCCCCCC
37.8226051181
1000 (in isoform 5)Phosphorylation-56.14-
1001 (in isoform 5)Phosphorylation-41.89-
1005PhosphorylationAPPPPQNLQPESDAP
CCCCCCCCCCCCCCC
8.2824719451
1006 (in isoform 5)Phosphorylation-47.46-
1007PhosphorylationPPPQNLQPESDAPQQ
CCCCCCCCCCCCCCC
46.3424719451
1008 (in isoform 5)Phosphorylation-48.57-
1009PhosphorylationPQNLQPESDAPQQPG
CCCCCCCCCCCCCCC
45.8422167270
1017PhosphorylationDAPQQPGSSPRGKSR
CCCCCCCCCCCCCCC
43.8023401153
1018PhosphorylationAPQQPGSSPRGKSRS
CCCCCCCCCCCCCCC
25.2429255136
1023PhosphorylationGSSPRGKSRSPAPPA
CCCCCCCCCCCCCCC
40.5923401153
1023 (in isoform 3)Phosphorylation-40.5926657352
1025PhosphorylationSPRGKSRSPAPPADK
CCCCCCCCCCCCCCH
32.2925159151
1025 (in isoform 3)Phosphorylation-32.2926657352
1118PhosphorylationSNPPPLISSAKHPSV
CCCCCCCCCCCCHHH
31.7428060719
1126O-linked_GlycosylationSAKHPSVLERQIGAI
CCCCHHHHHHHHCHH
5.4330059200
1126PhosphorylationSAKHPSVLERQIGAI
CCCCHHHHHHHHCHH
5.43-
1134PhosphorylationERQIGAISQGMSVQL
HHHHCHHHCCCEEEE
21.83-
1138O-linked_GlycosylationGAISQGMSVQLHVPY
CHHHCCCEEEEECCH
17.3430059200
1157PhosphorylationKAPVGPVTMGLPLPM
CCCCCCEECCCCCCC
14.5120068231
1160UbiquitinationVGPVTMGLPLPMDPK
CCCEECCCCCCCCHH
2.46-
1163PhosphorylationVTMGLPLPMDPKKLA
EECCCCCCCCHHHCC
24.1624719451
1168SumoylationPLPMDPKKLAPFSGV
CCCCCHHHCCCCCCC
56.09-
1173PhosphorylationPKKLAPFSGVKQEQL
HHHCCCCCCCCHHHC
41.4326074081
1176SumoylationLAPFSGVKQEQLSPR
CCCCCCCCHHHCCCC
52.20-
1176AcetylationLAPFSGVKQEQLSPR
CCCCCCCCHHHCCCC
52.2026051181
1176SumoylationLAPFSGVKQEQLSPR
CCCCCCCCHHHCCCC
52.2028112733
1181PhosphorylationGVKQEQLSPRGQAGP
CCCHHHCCCCCCCCC
16.5523401153
1189 (in isoform 5)Phosphorylation-42.78-
1191PhosphorylationGQAGPPESLGVPTAQ
CCCCCHHHHCCCCHH
35.8822199227
1193 (in isoform 5)Phosphorylation-32.41-
1196PhosphorylationPESLGVPTAQEASVL
HHHHCCCCHHHHHCC
38.2729514088
1197PhosphorylationESLGVPTAQEASVLR
HHHCCCCHHHHHCCC
10.1124719451
1198PhosphorylationSLGVPTAQEASVLRG
HHCCCCHHHHHCCCC
49.6320068231
1198 (in isoform 5)Phosphorylation-49.63-
1201PhosphorylationVPTAQEASVLRGTAL
CCCHHHHHCCCCCCC
22.4129514088
1201 (in isoform 5)Acetylation-22.41-
1202PhosphorylationPTAQEASVLRGTALG
CCHHHHHCCCCCCCC
5.6420068231
1206PhosphorylationEASVLRGTALGSVPG
HHHCCCCCCCCCCCC
16.5720068231
1207PhosphorylationASVLRGTALGSVPGG
HHCCCCCCCCCCCCC
16.8520068231
1210AcetylationLRGTALGSVPGGSIT
CCCCCCCCCCCCCCC
26.4519608861
1210PhosphorylationLRGTALGSVPGGSIT
CCCCCCCCCCCCCCC
26.4520068231
1210UbiquitinationLRGTALGSVPGGSIT
CCCCCCCCCCCCCCC
26.4519608861
1215O-linked_GlycosylationLGSVPGGSITKGIPS
CCCCCCCCCCCCCCC
32.7630059200
1215PhosphorylationLGSVPGGSITKGIPS
CCCCCCCCCCCCCCC
32.7620068231
1217PhosphorylationSVPGGSITKGIPSTR
CCCCCCCCCCCCCCC
25.5625159151
1218AcetylationVPGGSITKGIPSTRV
CCCCCCCCCCCCCCC
53.8519608861
1218UbiquitinationVPGGSITKGIPSTRV
CCCCCCCCCCCCCCC
53.85-
1219PhosphorylationPGGSITKGIPSTRVP
CCCCCCCCCCCCCCC
28.5227251275
1226MethylationGIPSTRVPSDSAITY
CCCCCCCCCCCCEEE
29.18-
1227PhosphorylationIPSTRVPSDSAITYR
CCCCCCCCCCCEEEC
41.1428857561
1231 (in isoform 5)Acetylation-3.94-
1233PhosphorylationPSDSAITYRGSITHG
CCCCCEEECCEECCC
13.58-
1234MethylationSDSAITYRGSITHGT
CCCCEEECCEECCCC
24.59115389607
1236PhosphorylationSAITYRGSITHGTPA
CCEEECCEECCCCCC
18.4723401153
1238PhosphorylationITYRGSITHGTPADV
EEECCEECCCCCCCE
18.8928555341
1240AcetylationYRGSITHGTPADVLY
ECCEECCCCCCCEEE
25.4119608861
1240SumoylationYRGSITHGTPADVLY
ECCEECCCCCCCEEE
25.4119608861
1241PhosphorylationRGSITHGTPADVLYK
CCEECCCCCCCEEEE
14.0129214152
1242 (in isoform 5)Phosphorylation-30.93-
1244 (in isoform 5)Phosphorylation-31.96-
1247PhosphorylationGTPADVLYKGTITRI
CCCCCEEEECEEEEE
13.7627642862
1248SumoylationTPADVLYKGTITRII
CCCCEEEECEEEEEE
45.47-
1248AcetylationTPADVLYKGTITRII
CCCCEEEECEEEEEE
45.4719608861
1251PhosphorylationDVLYKGTITRIIGED
CEEEECEEEEEECCC
3.1220068231
1252PhosphorylationVLYKGTITRIIGEDS
EEEECEEEEEECCCC
18.6924719451
1253PhosphorylationLYKGTITRIIGEDSP
EEECEEEEEECCCCH
18.0617081983
1259PhosphorylationTRIIGEDSPSRLDRG
EEEECCCCHHHCCCC
22.0723401153
1261PhosphorylationIIGEDSPSRLDRGRE
EECCCCHHHCCCCCC
49.8030266825
1262PhosphorylationIGEDSPSRLDRGRED
ECCCCHHHCCCCCCC
43.9527251275
1270PhosphorylationLDRGREDSLPKGHVI
CCCCCCCCCCCCEEE
41.6422210691
1273UbiquitinationGREDSLPKGHVIYEG
CCCCCCCCCEEEEEC
67.93-
1278PhosphorylationLPKGHVIYEGKKGHV
CCCCEEEEECCCCCE
19.9627642862
1281AcetylationGHVIYEGKKGHVLSY
CEEEEECCCCCEEEE
43.5825953088
1287PhosphorylationGKKGHVLSYEGGMSV
CCCCCEEEEECCEEE
21.7624114839
1288PhosphorylationKKGHVLSYEGGMSVT
CCCCEEEEECCEEEE
17.9024114839
1295PhosphorylationYEGGMSVTQCSKEDG
EECCEEEEEEECCCC
19.2924114839
1296PhosphorylationEGGMSVTQCSKEDGR
ECCEEEEEEECCCCC
27.6027251275
1298PhosphorylationGMSVTQCSKEDGRSS
CEEEEEEECCCCCCC
29.3024114839
1304PhosphorylationCSKEDGRSSSGPPHE
EECCCCCCCCCCCCC
34.0925849741
1305PhosphorylationSKEDGRSSSGPPHET
ECCCCCCCCCCCCCC
37.6429255136
1306PhosphorylationKEDGRSSSGPPHETA
CCCCCCCCCCCCCCC
57.4729255136
1308UbiquitinationDGRSSSGPPHETAAP
CCCCCCCCCCCCCCC
29.08-
1312PhosphorylationSSGPPHETAAPKRTY
CCCCCCCCCCCCCHH
25.7023312004
1313PhosphorylationSGPPHETAAPKRTYD
CCCCCCCCCCCCHHH
20.8424719451
1319PhosphorylationTAAPKRTYDMMEGRV
CCCCCCHHHHCCCCC
13.0829759185
1323O-linked_GlycosylationKRTYDMMEGRVGRAI
CCHHHHCCCCCHHHH
36.8930059200
1323PhosphorylationKRTYDMMEGRVGRAI
CCHHHHCCCCCHHHH
36.8919690332
1326PhosphorylationYDMMEGRVGRAISSA
HHHCCCCCHHHHHHH
10.0227251275
1331PhosphorylationGRVGRAISSASIEGL
CCCHHHHHHHCHHHH
20.9030266825
1332PhosphorylationRVGRAISSASIEGLM
CCHHHHHHHCHHHHH
21.6630266825
1332 (in isoform 5)Phosphorylation-21.66-
1334PhosphorylationGRAISSASIEGLMGR
HHHHHHHCHHHHHCC
24.1130266825
1341PhosphorylationSIEGLMGRAIPPERH
CHHHHHCCCCCCCCC
18.5120068231
1349PhosphorylationAIPPERHSPHHLKEQ
CCCCCCCCCHHHHHH
31.9530266825
1352MethylationPERHSPHHLKEQHHI
CCCCCCHHHHHHHCC
41.82-
1354PhosphorylationRHSPHHLKEQHHIRG
CCCCHHHHHHHCCCC
51.4727251275
1360MethylationLKEQHHIRGSITQGI
HHHHHCCCCCCCCCC
28.5783108337
1362PhosphorylationEQHHIRGSITQGIPR
HHHCCCCCCCCCCCH
16.7728555341
1364PhosphorylationHHIRGSITQGIPRSY
HCCCCCCCCCCCHHH
23.5728555341
1370PhosphorylationITQGIPRSYVEAQED
CCCCCCHHHHHHHHH
28.33-
1370 (in isoform 5)Sumoylation-28.33-
1373PhosphorylationGIPRSYVEAQEDYLR
CCCHHHHHHHHHHHH
36.0824719451
1374 (in isoform 5)Phosphorylation-14.18-
1378PhosphorylationYVEAQEDYLRREAKL
HHHHHHHHHHHHHHH
11.0120562096
1383PhosphorylationEDYLRREAKLLKREG
HHHHHHHHHHHHCCC
13.1419664994
1387SumoylationRREAKLLKREGTPPP
HHHHHHHHCCCCCCC
59.8617000644
1391PhosphorylationKLLKREGTPPPPPPS
HHHHCCCCCCCCCCC
28.0619664994
1398PhosphorylationTPPPPPPSRDLTEAY
CCCCCCCCCCCHHHH
44.1723927012
1402PhosphorylationPPPSRDLTEAYKTQA
CCCCCCCHHHHHHHC
23.9026074081
1408SumoylationLTEAYKTQALGPLKL
CHHHHHHHCCCCCCC
30.36-
1408UbiquitinationLTEAYKTQALGPLKL
CHHHHHHHCCCCCCC
30.36-
1414PhosphorylationTQALGPLKLKPAHEG
HHCCCCCCCCCCCCC
58.5624719451
1416SumoylationALGPLKLKPAHEGLV
CCCCCCCCCCCCCCC
38.27-
1416AcetylationALGPLKLKPAHEGLV
CCCCCCCCCCCCCCC
38.2726051181
1424PhosphorylationPAHEGLVATVKEAGR
CCCCCCCHHHHHHCC
16.24-
1426PhosphorylationHEGLVATVKEAGRSI
CCCCCHHHHHHCCCH
3.6824719451
1432PhosphorylationTVKEAGRSIHEIPRE
HHHHHCCCHHCCCHH
27.6429214152
1436PhosphorylationAGRSIHEIPREELRH
HCCCHHCCCHHHHCC
2.1127251275
1444PhosphorylationPREELRHTPELPLAP
CHHHHCCCCCCCCCC
16.4230266825
1449 (in isoform 5)Sumoylation-18.74-
1450PhosphorylationHTPELPLAPRPLKEG
CCCCCCCCCCCCCCC
8.9827251275
1452PhosphorylationPELPLAPRPLKEGSI
CCCCCCCCCCCCCCC
43.50-
1455PhosphorylationPLAPRPLKEGSITQG
CCCCCCCCCCCCCCC
63.8127251275
1458PhosphorylationPRPLKEGSITQGTPL
CCCCCCCCCCCCCCC
24.4522199227
1458SumoylationPRPLKEGSITQGTPL
CCCCCCCCCCCCCCC
24.45-
1458UbiquitinationPRPLKEGSITQGTPL
CCCCCCCCCCCCCCC
24.45-
1460PhosphorylationPLKEGSITQGTPLKY
CCCCCCCCCCCCCEE
23.7322199227
1463PhosphorylationEGSITQGTPLKYDTG
CCCCCCCCCCEECCC
18.6829255136
1464PhosphorylationGSITQGTPLKYDTGA
CCCCCCCCCEECCCC
33.41-
1466SumoylationITQGTPLKYDTGAST
CCCCCCCEECCCCCC
42.14-
1466SumoylationITQGTPLKYDTGAST
CCCCCCCEECCCCCC
42.1417000644
14692-HydroxyisobutyrylationGTPLKYDTGASTTGS
CCCCEECCCCCCCCC
31.40-
1469PhosphorylationGTPLKYDTGASTTGS
CCCCEECCCCCCCCC
31.4024719451
1470 (in isoform 5)Phosphorylation-18.03-
1472PhosphorylationLKYDTGASTTGSKKH
CEECCCCCCCCCCHH
28.0424275569
1475PhosphorylationDTGASTTGSKKHDVR
CCCCCCCCCCHHCHH
37.24-
1479PhosphorylationSTTGSKKHDVRSLIG
CCCCCCHHCHHHHCC
42.4018669648
1483PhosphorylationSKKHDVRSLIGSPGR
CCHHCHHHHCCCCCC
24.9623927012
1487PhosphorylationDVRSLIGSPGRTFPP
CHHHHCCCCCCCCCC
19.7223401153
1491PhosphorylationLIGSPGRTFPPVHPL
HCCCCCCCCCCCCCH
46.5427422710
1504PhosphorylationPLDVMADARALERAC
CHHHHHHHHHHHHHH
6.79-
1509UbiquitinationADARALERACYEESL
HHHHHHHHHHHHHHH
30.70-
1510O-linked_GlycosylationDARALERACYEESLK
HHHHHHHHHHHHHHH
7.2930059200
1512PhosphorylationRALERACYEESLKSR
HHHHHHHHHHHHHCC
23.0317384208
1514O-linked_GlycosylationLERACYEESLKSRPG
HHHHHHHHHHHCCCC
34.5930059200
1516O-linked_GlycosylationRACYEESLKSRPGTA
HHHHHHHHHCCCCCC
7.0830059200
1517AcetylationACYEESLKSRPGTAS
HHHHHHHHCCCCCCC
54.4126051181
1517O-linked_GlycosylationACYEESLKSRPGTAS
HHHHHHHHCCCCCCC
54.4130059200
1517UbiquitinationACYEESLKSRPGTAS
HHHHHHHHCCCCCCC
54.41-
1518PhosphorylationCYEESLKSRPGTASS
HHHHHHHCCCCCCCC
49.34-
1521O-linked_GlycosylationESLKSRPGTASSSGG
HHHHCCCCCCCCCCC
32.5730059200
1522PhosphorylationSLKSRPGTASSSGGS
HHHCCCCCCCCCCCC
26.5030278072
1525 (in isoform 4)O-linked_Glycosylation-30.4530059200
1526PhosphorylationRPGTASSSGGSIARG
CCCCCCCCCCCHHCC
44.6825159151
1529PhosphorylationTASSSGGSIARGAPV
CCCCCCCCHHCCCCE
19.3224719451
1530 (in isoform 5)Phosphorylation-3.24-
1533 (in isoform 5)Phosphorylation-25.80-
1535AcetylationGSIARGAPVIVPELG
CCHHCCCCEEECCCC
21.13-
1535SumoylationGSIARGAPVIVPELG
CCHHCCCCEEECCCC
21.13-
1539PhosphorylationRGAPVIVPELGKPRQ
CCCCEEECCCCCCCC
21.7017081983
1542PhosphorylationPVIVPELGKPRQSPL
CEEECCCCCCCCCCC
35.9417081983
1543SumoylationVIVPELGKPRQSPLT
EEECCCCCCCCCCCC
50.04-
1543AcetylationVIVPELGKPRQSPLT
EEECCCCCCCCCCCC
50.0423749302
1543PhosphorylationVIVPELGKPRQSPLT
EEECCCCCCCCCCCC
50.0427251275
1547PhosphorylationELGKPRQSPLTYEDH
CCCCCCCCCCCCCCC
24.1330266825
1548PhosphorylationLGKPRQSPLTYEDHG
CCCCCCCCCCCCCCC
22.0024719451
1550PhosphorylationKPRQSPLTYEDHGAP
CCCCCCCCCCCCCCC
28.4030266825
1551PhosphorylationPRQSPLTYEDHGAPF
CCCCCCCCCCCCCCC
27.3523663014
1552PhosphorylationRQSPLTYEDHGAPFA
CCCCCCCCCCCCCCC
37.9924719451
1556MethylationLTYEDHGAPFAGHLP
CCCCCCCCCCCCCCC
7.82-
1556PhosphorylationLTYEDHGAPFAGHLP
CCCCCCCCCCCCCCC
7.8224719451
1558PhosphorylationYEDHGAPFAGHLPRG
CCCCCCCCCCCCCCC
14.6027251275
1561O-linked_GlycosylationHGAPFAGHLPRGSPV
CCCCCCCCCCCCCCC
29.2730059200
1562O-linked_GlycosylationGAPFAGHLPRGSPVT
CCCCCCCCCCCCCCC
2.7930059200
1563MethylationAPFAGHLPRGSPVTT
CCCCCCCCCCCCCCC
32.67-
1564MethylationPFAGHLPRGSPVTTR
CCCCCCCCCCCCCCC
65.66115917305
1564 (in isoform 5)Phosphorylation-65.66-
1566O-linked_GlycosylationAGHLPRGSPVTTREP
CCCCCCCCCCCCCCC
19.9230059200
1566PhosphorylationAGHLPRGSPVTTREP
CCCCCCCCCCCCCCC
19.9225159151
1567 (in isoform 5)Phosphorylation-30.23-
1568MethylationHLPRGSPVTTREPTP
CCCCCCCCCCCCCCC
10.26-
1569O-linked_GlycosylationLPRGSPVTTREPTPR
CCCCCCCCCCCCCCC
24.4229654417
1569PhosphorylationLPRGSPVTTREPTPR
CCCCCCCCCCCCCCC
24.4230108239
1570O-linked_GlycosylationPRGSPVTTREPTPRL
CCCCCCCCCCCCCCC
33.0129654419
1570PhosphorylationPRGSPVTTREPTPRL
CCCCCCCCCCCCCCC
33.0130108239
1570 (in isoform 4)O-linked_Glycosylation-33.0130059200
1571MethylationRGSPVTTREPTPRLQ
CCCCCCCCCCCCCCC
38.2354559465
1573PhosphorylationSPVTTREPTPRLQEG
CCCCCCCCCCCCCCC
44.4020068231
1574PhosphorylationPVTTREPTPRLQEGS
CCCCCCCCCCCCCCC
19.1126074081
1576MethylationTTREPTPRLQEGSLS
CCCCCCCCCCCCCCC
52.02115917309
1576PhosphorylationTTREPTPRLQEGSLS
CCCCCCCCCCCCCCC
52.0217081983
1577O-linked_GlycosylationTREPTPRLQEGSLSS
CCCCCCCCCCCCCCC
5.9830059200
1577PhosphorylationTREPTPRLQEGSLSS
CCCCCCCCCCCCCCC
5.9824719451
1578UbiquitinationREPTPRLQEGSLSSS
CCCCCCCCCCCCCCC
55.04-
1581PhosphorylationTPRLQEGSLSSSKAS
CCCCCCCCCCCCCHH
25.0720068231
1583PhosphorylationRLQEGSLSSSKASQD
CCCCCCCCCCCHHHC
33.9721815630
1584PhosphorylationLQEGSLSSSKASQDR
CCCCCCCCCCHHHCC
40.9430576142
1584SumoylationLQEGSLSSSKASQDR
CCCCCCCCCCHHHCC
40.94-
1585PhosphorylationQEGSLSSSKASQDRK
CCCCCCCCCHHHCCC
28.9430576142
1586UbiquitinationEGSLSSSKASQDRKL
CCCCCCCCHHHCCCC
54.74-
1586 (in isoform 5)Phosphorylation-54.74-
1587PhosphorylationGSLSSSKASQDRKLT
CCCCCCCHHHCCCCC
17.8627251275
1588PhosphorylationSLSSSKASQDRKLTS
CCCCCCHHHCCCCCC
36.0324719451
1592SumoylationSKASQDRKLTSTPRE
CCHHHCCCCCCCHHH
65.49-
1594PhosphorylationASQDRKLTSTPREIA
HHHCCCCCCCHHHHH
33.3226074081
1595PhosphorylationSQDRKLTSTPREIAK
HHCCCCCCCHHHHHC
47.0220068231
1596PhosphorylationQDRKLTSTPREIAKS
HCCCCCCCHHHHHCC
22.5626074081
1599PhosphorylationKLTSTPREIAKSPHS
CCCCCHHHHHCCCCC
48.8024719451
1603PhosphorylationTPREIAKSPHSTVPE
CHHHHHCCCCCCCCC
20.8729255136
1606PhosphorylationEIAKSPHSTVPEHHP
HHHCCCCCCCCCCCC
34.1929255136
1607PhosphorylationIAKSPHSTVPEHHPH
HHCCCCCCCCCCCCC
36.7329255136
1609PhosphorylationKSPHSTVPEHHPHPI
CCCCCCCCCCCCCCC
34.9824719451
1610 (in isoform 5)Phosphorylation-50.95-
1616MethylationPEHHPHPISPYEHLL
CCCCCCCCCHHHHHH
6.19-
1617PhosphorylationEHHPHPISPYEHLLR
CCCCCCCCHHHHHHC
26.3621955146
1619PhosphorylationHPHPISPYEHLLRGV
CCCCCCHHHHHHCCC
14.8018212344
1624MethylationSPYEHLLRGVSGVDL
CHHHHHHCCCCCHHH
50.23115917313
1627PhosphorylationEHLLRGVSGVDLYRS
HHHHCCCCCHHHHHC
35.6018212344
1632PhosphorylationGVSGVDLYRSHIPLA
CCCCHHHHHCCCCCC
12.9523186163
1635O-linked_GlycosylationGVDLYRSHIPLAFDP
CHHHHHCCCCCCCCC
19.3830059200
1636O-linked_GlycosylationVDLYRSHIPLAFDPT
HHHHHCCCCCCCCCC
2.9330059200
1639MethylationYRSHIPLAFDPTSIP
HHCCCCCCCCCCCCC
11.05-
1647MethylationFDPTSIPRGIPLDAA
CCCCCCCCCCCHHHH
54.7458859591
1653MethylationPRGIPLDAAAAYYLP
CCCCCHHHHHHHHCH
13.4924129315
1661Asymmetric dimethylarginineAAAYYLPRHLAPNPT
HHHHHCHHHCCCCCC
34.55-
1661MethylationAAAYYLPRHLAPNPT
HHHHHCHHHCCCCCC
34.5524129315
1661PhosphorylationAAAYYLPRHLAPNPT
HHHHHCHHHCCCCCC
34.55-
1669PhosphorylationHLAPNPTYPHLYPPY
HCCCCCCCCCCCCCC
7.0122461510
1671MethylationAPNPTYPHLYPPYLI
CCCCCCCCCCCCCCC
27.81-
1679MethylationLYPPYLIRGYPDTAA
CCCCCCCCCCCCHHH
35.6897799341
1682MethylationPYLIRGYPDTAALEN
CCCCCCCCCHHHHHH
34.99-
1690MethylationDTAALENRQTIINDY
CHHHHHHHHHHHHHH
26.1697799347
1692PhosphorylationAALENRQTIINDYIT
HHHHHHHHHHHHHHH
22.1628270605
1697PhosphorylationRQTIINDYITSQQMH
HHHHHHHHHHHHHHH
11.1228270605
1699PhosphorylationTIINDYITSQQMHHN
HHHHHHHHHHHHHHH
17.7928270605
1700PhosphorylationIINDYITSQQMHHNA
HHHHHHHHHHHHHHH
14.6228270605
1709PhosphorylationQMHHNAATAMAQRAD
HHHHHHHHHHHHHHH
17.9828270605
1711MethylationHHNAATAMAQRADML
HHHHHHHHHHHHHHH
2.57-
1716MethylationTAMAQRADMLRGLSP
HHHHHHHHHHCCCCH
38.55-
1719MethylationAQRADMLRGLSPRES
HHHHHHHCCCCHHHH
37.0512018121
1722PhosphorylationADMLRGLSPRESSLA
HHHHCCCCHHHHHHH
25.4123532336
1724MethylationMLRGLSPRESSLALN
HHCCCCHHHHHHHHH
53.72115917317
1726PhosphorylationRGLSPRESSLALNYA
CCCCHHHHHHHHHCC
31.7523532336
1727PhosphorylationGLSPRESSLALNYAA
CCCHHHHHHHHHCCC
16.9528555341
1729MethylationSPRESSLALNYAAGP
CHHHHHHHHHCCCCC
8.84-
1737MethylationLNYAAGPRGIIDLSQ
HHCCCCCCCEEEHHH
48.2854559473
1740PhosphorylationAAGPRGIIDLSQVPH
CCCCCCEEEHHHCCC
4.9224719451
1750PhosphorylationSQVPHLPVLVPPTPG
HHCCCCCEECCCCCC
12.08-
1758PhosphorylationLVPPTPGTPATAMDR
ECCCCCCCCCCHHHH
15.7924719451
1763PhosphorylationPGTPATAMDRLAYLP
CCCCCCHHHHHHCCC
2.4024719451
1764PhosphorylationGTPATAMDRLAYLPT
CCCCCHHHHHHCCCC
39.7224719451
1764 (in isoform 5)Phosphorylation-39.72-
1765 (in isoform 5)Phosphorylation-14.24-
1766 (in isoform 5)Phosphorylation-2.98-
1768PhosphorylationTAMDRLAYLPTAPQP
CHHHHHHCCCCCCCC
20.1524719451
1769 (in isoform 5)Phosphorylation-2.24-
1773PhosphorylationLAYLPTAPQPFSSRH
HHCCCCCCCCCCCCC
44.8717081983
1774PhosphorylationAYLPTAPQPFSSRHS
HCCCCCCCCCCCCCC
49.5617081983
1774 (in isoform 5)Phosphorylation-49.56-
1775PhosphorylationYLPTAPQPFSSRHSS
CCCCCCCCCCCCCCC
29.9917081983
1777 (in isoform 5)Phosphorylation-32.90-
1778O-linked_GlycosylationTAPQPFSSRHSSSPL
CCCCCCCCCCCCCCC
34.1030059200
1778PhosphorylationTAPQPFSSRHSSSPL
CCCCCCCCCCCCCCC
34.1020068231
1778 (in isoform 5)Acetylation-34.10-
1781PhosphorylationQPFSSRHSSSPLSPG
CCCCCCCCCCCCCCC
31.2523927012
1782PhosphorylationPFSSRHSSSPLSPGG
CCCCCCCCCCCCCCC
29.8325159151
1783PhosphorylationFSSRHSSSPLSPGGP
CCCCCCCCCCCCCCC
32.6429255136
1786PhosphorylationRHSSSPLSPGGPTHL
CCCCCCCCCCCCCCC
25.5329255136
1787AcetylationHSSSPLSPGGPTHLT
CCCCCCCCCCCCCCC
60.4919608861
1791PhosphorylationPLSPGGPTHLTKPTT
CCCCCCCCCCCCCCC
32.5629255136
1794PhosphorylationPGGPTHLTKPTTTSS
CCCCCCCCCCCCCCC
27.6329255136
1795AcetylationGGPTHLTKPTTTSSS
CCCCCCCCCCCCCCC
46.8819608861
1797PhosphorylationPTHLTKPTTTSSSER
CCCCCCCCCCCCCHH
44.2423403867
1798PhosphorylationTHLTKPTTTSSSERE
CCCCCCCCCCCCHHH
32.9623403867
1799PhosphorylationHLTKPTTTSSSERER
CCCCCCCCCCCHHHH
29.1423403867
1799 (in isoform 4)O-linked_Glycosylation-29.1430059200
1800PhosphorylationLTKPTTTSSSERERD
CCCCCCCCCCHHHHH
29.7623403867
1801PhosphorylationTKPTTTSSSERERDR
CCCCCCCCCHHHHHH
33.8423403867
1802PhosphorylationKPTTTSSSERERDRD
CCCCCCCCHHHHHHH
40.2023403867
1817O-linked_GlycosylationRERDRDREREKSILT
HHHHHHHHHHHHHHC
70.2730059200
1821PhosphorylationRDREREKSILTSTTT
HHHHHHHHHHCCCCE
20.3426074081
1824PhosphorylationEREKSILTSTTTVEH
HHHHHHHCCCCEEEC
23.5126074081
1825PhosphorylationREKSILTSTTTVEHA
HHHHHHCCCCEEECC
21.9526074081
1826PhosphorylationEKSILTSTTTVEHAP
HHHHHCCCCEEECCC
22.6626074081
1827PhosphorylationKSILTSTTTVEHAPI
HHHHCCCCEEECCCC
28.7226074081
1828PhosphorylationSILTSTTTVEHAPIW
HHHCCCCEEECCCCC
24.8026074081
1831O-linked_GlycosylationTSTTTVEHAPIWRPG
CCCCEEECCCCCCCC
32.2530059200
1844 (in isoform 5)Phosphorylation-30.95-
1846PhosphorylationTEQSSGSSGSSGGGG
CCCCCCCCCCCCCCC
46.3419651622
1846 (in isoform 5)Phosphorylation-46.34-
1850PhosphorylationSGSSGSSGGGGGSSS
CCCCCCCCCCCCCCC
40.2320068231
1852PhosphorylationSSGSSGGGGGSSSRP
CCCCCCCCCCCCCCC
40.5919651622
1852 (in isoform 5)Phosphorylation-40.59-
1855PhosphorylationSSGGGGGSSSRPASH
CCCCCCCCCCCCCCC
28.5420068231
1855 (in isoform 5)Phosphorylation-28.54-
1858PhosphorylationGGGGSSSRPASHSHA
CCCCCCCCCCCCCCC
32.5220068231
1861PhosphorylationGSSSRPASHSHAHQH
CCCCCCCCCCCCCCC
28.3628796482
1863PhosphorylationSSRPASHSHAHQHSP
CCCCCCCCCCCCCCC
21.6328796482
1869PhosphorylationHSHAHQHSPISPRTQ
CCCCCCCCCCCHHHH
19.8429255136
1872PhosphorylationAHQHSPISPRTQDAL
CCCCCCCCHHHHHHH
16.2429255136
1875PhosphorylationHSPISPRTQDALQQR
CCCCCHHHHHHHHHC
33.9023312004
1881PhosphorylationRTQDALQQRPSVLHN
HHHHHHHHCCCHHHH
61.1624719451
1884PhosphorylationDALQQRPSVLHNTGM
HHHHHCCCHHHHCCC
39.2323312004
1889PhosphorylationRPSVLHNTGMKGIIT
CCCHHHHCCCCCEEE
28.0923312004
1890PhosphorylationPSVLHNTGMKGIITA
CCHHHHCCCCCEEEE
22.56-
1891PhosphorylationSVLHNTGMKGIITAV
CHHHHCCCCCEEEEE
3.1927251275
1892AcetylationVLHNTGMKGIITAVE
HHHHCCCCCEEEEEC
48.5825953088
1897PhosphorylationGMKGIITAVEPSTPT
CCCCEEEEECCCCCC
8.0227251275
1900PhosphorylationGIITAVEPSTPTVLR
CEEEEECCCCCCEEE
36.5827251275
1901PhosphorylationIITAVEPSTPTVLRS
EEEEECCCCCCEEEC
33.2522199227
1902PhosphorylationITAVEPSTPTVLRST
EEEECCCCCCEEECC
33.4225159151
1904PhosphorylationAVEPSTPTVLRSTST
EECCCCCCEEECCCC
32.0622199227
1908PhosphorylationSTPTVLRSTSTSSPV
CCCCEEECCCCCCCC
23.6625159151
1909O-linked_GlycosylationTPTVLRSTSTSSPVR
CCCEEECCCCCCCCC
29.5930059200
1909PhosphorylationTPTVLRSTSTSSPVR
CCCEEECCCCCCCCC
29.5929978859
1910PhosphorylationPTVLRSTSTSSPVRP
CCEEECCCCCCCCCC
27.7829978859
1911PhosphorylationTVLRSTSTSSPVRPA
CEEECCCCCCCCCCC
33.0630206219
1912PhosphorylationVLRSTSTSSPVRPAA
EEECCCCCCCCCCCC
32.2025159151
1913PhosphorylationLRSTSTSSPVRPAAT
EECCCCCCCCCCCCC
27.7425159151
1920PhosphorylationSPVRPAATFPPATHC
CCCCCCCCCCCCCCC
38.4928464451
1925PhosphorylationAATFPPATHCPLGGT
CCCCCCCCCCCCCCC
29.7730206219
1932PhosphorylationTHCPLGGTLDGVYPT
CCCCCCCCCCCCCCC
21.6330206219
1937PhosphorylationGGTLDGVYPTLMEPV
CCCCCCCCCCCCCCC
8.9530206219
1939PhosphorylationTLDGVYPTLMEPVLL
CCCCCCCCCCCCCCC
22.5021406692
1942PhosphorylationGVYPTLMEPVLLPKE
CCCCCCCCCCCCCCC
35.0624719451
1952PhosphorylationLLPKEAPRVARPERP
CCCCCCCCCCCCCCC
41.6027251275
1953 (in isoform 5)Acetylation-5.29-
1954PhosphorylationPKEAPRVARPERPRA
CCCCCCCCCCCCCCC
23.6924719451
1958 (in isoform 5)Phosphorylation-28.78-
1959AcetylationRVARPERPRADTGHA
CCCCCCCCCCCCCCC
33.8619608861
1963PhosphorylationPERPRADTGHAFLAK
CCCCCCCCCCCEECC
29.8625159151
1964PhosphorylationERPRADTGHAFLAKP
CCCCCCCCCCEECCC
15.6320068231
1964 (in isoform 5)Phosphorylation-15.63-
1965 (in isoform 5)Phosphorylation-18.52-
1967 (in isoform 5)Phosphorylation-5.90-
1970AcetylationTGHAFLAKPPARSGL
CCCCEECCCCCCCCC
54.3919608861
1970PhosphorylationTGHAFLAKPPARSGL
CCCCEECCCCCCCCC
54.3919651622
1971PhosphorylationGHAFLAKPPARSGLE
CCCEECCCCCCCCCC
23.3620068231
1973PhosphorylationAFLAKPPARSGLEPA
CEECCCCCCCCCCCC
27.1419651622
1974PhosphorylationFLAKPPARSGLEPAS
EECCCCCCCCCCCCC
36.7115302935
1975PhosphorylationLAKPPARSGLEPASS
ECCCCCCCCCCCCCC
50.2423927012
1976PhosphorylationAKPPARSGLEPASSP
CCCCCCCCCCCCCCC
28.62-
1981PhosphorylationRSGLEPASSPSKGSE
CCCCCCCCCCCCCCC
54.2029255136
1982PhosphorylationSGLEPASSPSKGSEP
CCCCCCCCCCCCCCC
34.9929255136
1984PhosphorylationLEPASSPSKGSEPRP
CCCCCCCCCCCCCCC
52.1530266825
1986O-linked_GlycosylationPASSPSKGSEPRPLV
CCCCCCCCCCCCCCC
41.3930059200
1986PhosphorylationPASSPSKGSEPRPLV
CCCCCCCCCCCCCCC
41.39-
1987PhosphorylationASSPSKGSEPRPLVP
CCCCCCCCCCCCCCC
48.4330266825
1990O-linked_GlycosylationPSKGSEPRPLVPPVS
CCCCCCCCCCCCCCC
32.8830059200
1995PhosphorylationEPRPLVPPVSGHATI
CCCCCCCCCCCCCEE
25.9824719451
1997PhosphorylationRPLVPPVSGHATIAR
CCCCCCCCCCCEEEC
30.5424732914
1997 (in isoform 4)O-linked_Glycosylation-30.5430059200
1999 (in isoform 5)Phosphorylation-16.52-
2001PhosphorylationPPVSGHATIARTPAK
CCCCCCCEEECCCCC
14.9724732914
2005PhosphorylationGHATIARTPAKNLAP
CCCEEECCCCCCCCC
20.6920068231
2008PhosphorylationTIARTPAKNLAPHHA
EEECCCCCCCCCCCC
54.4117081983
2008 (in isoform 5)Phosphorylation-54.41-
2014PhosphorylationAKNLAPHHASPDPPA
CCCCCCCCCCCCCCC
27.1817081983
2016PhosphorylationNLAPHHASPDPPAPP
CCCCCCCCCCCCCCC
26.0229255136
2016 (in isoform 5)Acetylation-26.02-
2020 (in isoform 5)Acetylation-65.85-
2022AcetylationASPDPPAPPASASDP
CCCCCCCCCCCCCCC
30.6619608861
2025O-linked_GlycosylationDPPAPPASASDPHRE
CCCCCCCCCCCCCCC
33.7930059200
2025PhosphorylationDPPAPPASASDPHRE
CCCCCCCCCCCCCCC
33.7927794612
2026AcetylationPPAPPASASDPHREK
CCCCCCCCCCCCCCC
21.7619608861
2026SumoylationPPAPPASASDPHREK
CCCCCCCCCCCCCCC
21.7619608861
2026UbiquitinationPPAPPASASDPHREK
CCCCCCCCCCCCCCC
21.7619608861
2027PhosphorylationPAPPASASDPHREKT
CCCCCCCCCCCCCCC
49.5326307563
2033AcetylationASDPHREKTQSKPFS
CCCCCCCCCCCCCCC
52.3926051181
2034PhosphorylationSDPHREKTQSKPFSI
CCCCCCCCCCCCCCH
33.0724719451
2034 (in isoform 5)Phosphorylation-33.07-
2037SumoylationHREKTQSKPFSIQEL
CCCCCCCCCCCHHHE
40.02-
2037AcetylationHREKTQSKPFSIQEL
CCCCCCCCCCCHHHE
40.0219608861
2037PhosphorylationHREKTQSKPFSIQEL
CCCCCCCCCCCHHHE
40.02-
2037 (in isoform 5)Phosphorylation-40.02-
2038 (in isoform 5)Phosphorylation-33.20-
2039 (in isoform 5)Phosphorylation-13.28-
2040PhosphorylationKTQSKPFSIQELELR
CCCCCCCCHHHEEHH
31.7118669648
2040 (in isoform 5)Phosphorylation-31.71-
2043PhosphorylationSKPFSIQELELRSLG
CCCCCHHHEEHHHCC
42.4118669648
2044PhosphorylationKPFSIQELELRSLGY
CCCCHHHEEHHHCCC
4.2724719451
2045PhosphorylationPFSIQELELRSLGYH
CCCHHHEEHHHCCCC
41.1918669648
2046PhosphorylationFSIQELELRSLGYHG
CCHHHEEHHHCCCCC
7.6218669648
2048PhosphorylationIQELELRSLGYHGSS
HHHEEHHHCCCCCCC
38.4823927012
2048 (in isoform 5)Phosphorylation-38.48-
2049PhosphorylationQELELRSLGYHGSSY
HHEEHHHCCCCCCCC
6.8018669648
2051PhosphorylationLELRSLGYHGSSYSP
EEHHHCCCCCCCCCC
14.3223927012
2051 (in isoform 5)Phosphorylation-14.32-
2052 (in isoform 5)Phosphorylation-28.06-
2054PhosphorylationRSLGYHGSSYSPEGV
HHCCCCCCCCCCCCC
16.8823927012
2054 (in isoform 5)Phosphorylation-16.88-
2055PhosphorylationSLGYHGSSYSPEGVE
HCCCCCCCCCCCCCC
33.9323401153
2056PhosphorylationLGYHGSSYSPEGVEP
CCCCCCCCCCCCCCC
29.9123927012
2056 (in isoform 5)Phosphorylation-29.91-
2057PhosphorylationGYHGSSYSPEGVEPV
CCCCCCCCCCCCCCC
20.5823927012
2058PhosphorylationYHGSSYSPEGVEPVS
CCCCCCCCCCCCCCC
33.8417081983
2060PhosphorylationGSSYSPEGVEPVSPV
CCCCCCCCCCCCCCC
32.2618669648
2061PhosphorylationSSYSPEGVEPVSPVS
CCCCCCCCCCCCCCC
7.7717081983
2062PhosphorylationSYSPEGVEPVSPVSS
CCCCCCCCCCCCCCC
51.3324275569
2065PhosphorylationPEGVEPVSPVSSPSL
CCCCCCCCCCCCCCC
30.2423927012
2067PhosphorylationGVEPVSPVSSPSLTH
CCCCCCCCCCCCCCC
7.4324719451
2068PhosphorylationVEPVSPVSSPSLTHD
CCCCCCCCCCCCCCC
39.6623927012
2069PhosphorylationEPVSPVSSPSLTHDK
CCCCCCCCCCCCCCC
20.8123927012
2069SumoylationEPVSPVSSPSLTHDK
CCCCCCCCCCCCCCC
20.81-
2069UbiquitinationEPVSPVSSPSLTHDK
CCCCCCCCCCCCCCC
20.81-
2071PhosphorylationVSPVSSPSLTHDKGL
CCCCCCCCCCCCCCC
48.0923927012
2073PhosphorylationPVSSPSLTHDKGLPK
CCCCCCCCCCCCCHH
32.1623927012
2076AcetylationSPSLTHDKGLPKHLE
CCCCCCCCCCHHHHH
55.5326051181
2076UbiquitinationSPSLTHDKGLPKHLE
CCCCCCCCCCHHHHH
55.53-
2077PhosphorylationPSLTHDKGLPKHLEE
CCCCCCCCCHHHHHH
53.9523186163
2080SumoylationTHDKGLPKHLEELDK
CCCCCCHHHHHHHHH
66.90-
2086UbiquitinationPKHLEELDKSHLEGE
HHHHHHHHHHHHCCC
54.41-
2087AcetylationKHLEELDKSHLEGEL
HHHHHHHHHHHCCCC
53.0226051181
2088PhosphorylationHLEELDKSHLEGELR
HHHHHHHHHHCCCCC
32.7330576142
2102PhosphorylationRPKQPGPVKLGGEAA
CCCCCCCCCCCCCCC
11.2224719451
2112PhosphorylationGGEAAHLPHLRPLPE
CCCCCCCCCCCCCCC
18.01-
2114PhosphorylationEAAHLPHLRPLPESQ
CCCCCCCCCCCCCCC
5.95-
2119PhosphorylationPHLRPLPESQPSSSP
CCCCCCCCCCCCCCC
70.4627251275
2120PhosphorylationHLRPLPESQPSSSPL
CCCCCCCCCCCCCCC
45.5125850435
2123PhosphorylationPLPESQPSSSPLLQT
CCCCCCCCCCCCCCC
35.4925850435
2124PhosphorylationLPESQPSSSPLLQTA
CCCCCCCCCCCCCCC
42.5325850435
2125PhosphorylationPESQPSSSPLLQTAP
CCCCCCCCCCCCCCC
24.7329496963
2130PhosphorylationSSSPLLQTAPGVKGH
CCCCCCCCCCCCCCH
34.4925850435
2131O-linked_GlycosylationSSPLLQTAPGVKGHQ
CCCCCCCCCCCCCHH
5.9630059200
2155PhosphorylationSEVITQDYTRHHPQQ
HHHHHCCCHHCCCCC
8.8927642862
2161PhosphorylationDYTRHHPQQLSAPLP
CCHHCCCCCCCCCCC
53.11-
2168PhosphorylationQQLSAPLPAPLYSFP
CCCCCCCCCCCCCCC
30.6724719451
2172PhosphorylationAPLPAPLYSFPGASC
CCCCCCCCCCCCCCC
13.7527642862
2173PhosphorylationPLPAPLYSFPGASCP
CCCCCCCCCCCCCCC
32.42-
2178PhosphorylationLYSFPGASCPVLDLR
CCCCCCCCCCEECCC
25.5227251275
2188 (in isoform 5)Phosphorylation-38.37-
2189PhosphorylationLDLRRPPSDLYLPPP
ECCCCCCHHCCCCCC
42.8228985074
2191 (in isoform 5)Phosphorylation-5.77-
2192PhosphorylationRRPPSDLYLPPPDHG
CCCCHHCCCCCCCCC
23.3527080861
2193PhosphorylationRPPSDLYLPPPDHGA
CCCHHCCCCCCCCCC
7.1624719451
2194PhosphorylationPPSDLYLPPPDHGAP
CCHHCCCCCCCCCCC
25.4817081983
2197PhosphorylationDLYLPPPDHGAPARG
HCCCCCCCCCCCCCC
59.6417081983
2197 (in isoform 5)Phosphorylation-59.64-
2200PhosphorylationLPPPDHGAPARGSPH
CCCCCCCCCCCCCCC
7.3717081983
2203PhosphorylationPDHGAPARGSPHSEG
CCCCCCCCCCCCCCC
45.0917081983
2205PhosphorylationHGAPARGSPHSEGGK
CCCCCCCCCCCCCCC
17.5626055452
2208PhosphorylationPARGSPHSEGGKRSP
CCCCCCCCCCCCCCC
41.1227362937
2213PhosphorylationPHSEGGKRSPEPNKT
CCCCCCCCCCCCCCC
61.8024719451
2214PhosphorylationHSEGGKRSPEPNKTS
CCCCCCCCCCCCCCC
36.7821955146
2217 (in isoform 5)Phosphorylation-51.51-
2220PhosphorylationRSPEPNKTSVLGGGE
CCCCCCCCCCCCCCC
30.6123403867
2221PhosphorylationSPEPNKTSVLGGGED
CCCCCCCCCCCCCCC
19.5628464451
2223PhosphorylationEPNKTSVLGGGEDGI
CCCCCCCCCCCCCCC
5.4520068231
2223 (in isoform 5)Phosphorylation-5.45-
2229PhosphorylationVLGGGEDGIEPVSPP
CCCCCCCCCCCCCCC
23.1217081983
2234PhosphorylationEDGIEPVSPPEGMTE
CCCCCCCCCCCCCCC
45.5129255136
2236PhosphorylationGIEPVSPPEGMTEPG
CCCCCCCCCCCCCCC
43.1827251275
2239PhosphorylationPVSPPEGMTEPGHSR
CCCCCCCCCCCCCCH
3.51-
2240PhosphorylationVSPPEGMTEPGHSRS
CCCCCCCCCCCCCHH
50.3022167270
2245PhosphorylationGMTEPGHSRSAVYPL
CCCCCCCCHHHHHEE
33.5722167270
2247PhosphorylationTEPGHSRSAVYPLLY
CCCCCCHHHHHEEEE
25.7126074081
2248PhosphorylationEPGHSRSAVYPLLYR
CCCCCHHHHHEEEEC
12.0724719451
2250PhosphorylationGHSRSAVYPLLYRDG
CCCHHHHHEEEECCC
6.4617360941
2250 (in isoform 5)Phosphorylation-6.46-
2252 (in isoform 5)Phosphorylation-3.43-
2254PhosphorylationSAVYPLLYRDGEQTE
HHHHEEEECCCCCCC
17.8426074081
2256PhosphorylationVYPLLYRDGEQTEPS
HHEEEECCCCCCCCC
51.9620068231
2256 (in isoform 5)Phosphorylation-51.96-
2257 (in isoform 5)Phosphorylation-21.66-
2258PhosphorylationPLLYRDGEQTEPSRM
EEEECCCCCCCCCCC
59.6319664995
2261PhosphorylationYRDGEQTEPSRMGSK
ECCCCCCCCCCCCCC
40.7617081983
2262PhosphorylationRDGEQTEPSRMGSKS
CCCCCCCCCCCCCCC
30.5318767875
2263PhosphorylationDGEQTEPSRMGSKSP
CCCCCCCCCCCCCCC
28.7720068231
2265PhosphorylationEQTEPSRMGSKSPGN
CCCCCCCCCCCCCCC
9.2524719451
2267PhosphorylationTEPSRMGSKSPGNTS
CCCCCCCCCCCCCCC
22.1823401153
2269PhosphorylationPSRMGSKSPGNTSQP
CCCCCCCCCCCCCCC
39.4729255136
2273PhosphorylationGSKSPGNTSQPPAFF
CCCCCCCCCCCCHHH
34.3522167270
2274PhosphorylationSKSPGNTSQPPAFFS
CCCCCCCCCCCHHHH
44.6930266825
2275PhosphorylationKSPGNTSQPPAFFSK
CCCCCCCCCCHHHHH
46.05-
2281PhosphorylationSQPPAFFSKLTESNS
CCCCHHHHHHHHCCC
21.9423927012
2281SumoylationSQPPAFFSKLTESNS
CCCCHHHHHHHHCCC
21.94-
2284PhosphorylationPAFFSKLTESNSAMV
CHHHHHHHHCCCHHH
40.9029038488
2286PhosphorylationFFSKLTESNSAMVKS
HHHHHHHCCCHHHHH
30.7425159151
2292SumoylationESNSAMVKSKKQEIN
HCCCHHHHHHHHHHH
43.40-
2312PhosphorylationHNRNEPEYNISQPGT
CCCCCCCCCCCCCCC
28.6324043423
2315PhosphorylationNEPEYNISQPGTEIF
CCCCCCCCCCCCEEC
27.0424043423
2319PhosphorylationYNISQPGTEIFNMPA
CCCCCCCCEECCCCC
32.3724043423
2328PhosphorylationIFNMPAITGTGLMTY
ECCCCCCCCCCHHHH
30.6924043423
2330PhosphorylationNMPAITGTGLMTYRS
CCCCCCCCCHHHHHH
20.6324043423
2334PhosphorylationITGTGLMTYRSQAVQ
CCCCCHHHHHHHHHH
22.3324043423
2335PhosphorylationTGTGLMTYRSQAVQE
CCCCHHHHHHHHHHH
8.3624043423
2368PhosphorylationKYDQWEESPPLSANA
CCCCCCCCCCCCCCC
21.9417081983
2368 (in isoform 5)Phosphorylation-21.94-
2372PhosphorylationWEESPPLSANAFNPL
CCCCCCCCCCCCCCC
25.8328348404
2374 (in isoform 5)Phosphorylation-41.51-
2376 (in isoform 5)Phosphorylation-10.97-
2377 (in isoform 5)Phosphorylation-37.43-
2380 (in isoform 5)Phosphorylation-32.86-
2382PhosphorylationAFNPLNASASLPAAM
CCCCCCCCCCCCCCC
19.8128348404
2383PhosphorylationFNPLNASASLPAAMP
CCCCCCCCCCCCCCC
16.8124719451
2392PhosphorylationLPAAMPITAADGRSD
CCCCCCEECCCCCCC
15.2118669648
2393PhosphorylationPAAMPITAADGRSDH
CCCCCEECCCCCCCC
12.3220068231
2398PhosphorylationITAADGRSDHTLTSP
EECCCCCCCCCCCCC
38.9927251275
2400 (in isoform 5)Phosphorylation-24.83-
2401PhosphorylationADGRSDHTLTSPGGG
CCCCCCCCCCCCCCC
36.4023663014
2401 (in isoform 5)Phosphorylation-36.40-
2403PhosphorylationGRSDHTLTSPGGGGK
CCCCCCCCCCCCCCC
33.7530266825
2404PhosphorylationRSDHTLTSPGGGGKA
CCCCCCCCCCCCCCC
25.3530266825
2404 (in isoform 5)Phosphorylation-25.35-
2405 (in isoform 5)Phosphorylation-39.97-
2407PhosphorylationHTLTSPGGGGKAKVS
CCCCCCCCCCCCEEC
45.0915494311
2410PhosphorylationTSPGGGGKAKVSGRP
CCCCCCCCCEECCCC
48.5924719451
2413PhosphorylationGGGGKAKVSGRPSSR
CCCCCCEECCCCCCC
9.7817081983
2416PhosphorylationGKAKVSGRPSSRKAK
CCCEECCCCCCCCCC
22.0317081983
2418PhosphorylationAKVSGRPSSRKAKSP
CEECCCCCCCCCCCC
41.2215494311
2420PhosphorylationVSGRPSSRKAKSPAP
ECCCCCCCCCCCCCC
47.4917081983
2422PhosphorylationGRPSSRKAKSPAPGL
CCCCCCCCCCCCCCC
19.2224719451
2424PhosphorylationPSSRKAKSPAPGLAS
CCCCCCCCCCCCCCC
31.0223401153
2426PhosphorylationSRKAKSPAPGLASGD
CCCCCCCCCCCCCCC
20.2017081983
2428PhosphorylationKAKSPAPGLASGDRP
CCCCCCCCCCCCCCC
35.6617081983
2429PhosphorylationAKSPAPGLASGDRPP
CCCCCCCCCCCCCCC
3.1417081983
2431PhosphorylationSPAPGLASGDRPPSV
CCCCCCCCCCCCCCC
46.3921955146
2432PhosphorylationPAPGLASGDRPPSVS
CCCCCCCCCCCCCCC
29.3717081983
2437PhosphorylationASGDRPPSVSSVHSE
CCCCCCCCCCCCCCC
37.0021955146
2439PhosphorylationGDRPPSVSSVHSEGD
CCCCCCCCCCCCCCC
30.8621955146
2440PhosphorylationDRPPSVSSVHSEGDC
CCCCCCCCCCCCCCC
22.9921955146
2443PhosphorylationPSVSSVHSEGDCNRR
CCCCCCCCCCCCCCC
40.9121955146
2446PhosphorylationSSVHSEGDCNRRTPL
CCCCCCCCCCCCCCC
23.5924719451
2451PhosphorylationEGDCNRRTPLTNRVW
CCCCCCCCCCCCCCC
21.2928348404
2452PhosphorylationGDCNRRTPLTNRVWE
CCCCCCCCCCCCCCC
35.0620068231
2453PhosphorylationDCNRRTPLTNRVWED
CCCCCCCCCCCCCCC
7.0117081983
2456PhosphorylationRRTPLTNRVWEDRPS
CCCCCCCCCCCCCCC
29.6820068231
2457PhosphorylationRTPLTNRVWEDRPSS
CCCCCCCCCCCCCCC
7.7220068231
2457 (in isoform 5)Phosphorylation-7.72-
2459 (in isoform 5)Phosphorylation-41.09-
2461 (in isoform 5)Phosphorylation-22.83-
2463PhosphorylationRVWEDRPSSAGSTPF
CCCCCCCCCCCCCCC
33.4423927012
2464PhosphorylationVWEDRPSSAGSTPFP
CCCCCCCCCCCCCCC
39.0523927012
2467PhosphorylationDRPSSAGSTPFPYNP
CCCCCCCCCCCCCCC
32.4023927012
2468PhosphorylationRPSSAGSTPFPYNPL
CCCCCCCCCCCCCCH
28.2023927012
2472PhosphorylationAGSTPFPYNPLIMRL
CCCCCCCCCCHHHHH
29.7723927012
2475PhosphorylationTPFPYNPLIMRLQAG
CCCCCCCHHHHHCCC
4.23-
2486PhosphorylationLQAGVMASPPPPGLP
HCCCCCCCCCCCCCC
21.6125159151
2496PhosphorylationPPGLPAGSGPLAGPH
CCCCCCCCCCCCCCC
39.0728348404
2509PhosphorylationPHHAWDEEPKPLLCS
CCCCCCCCCCCCCCC
57.0318669648
2511PhosphorylationHAWDEEPKPLLCSQY
CCCCCCCCCCCCCCE
52.1317081983
2513PhosphorylationWDEEPKPLLCSQYET
CCCCCCCCCCCCEEE
10.5917081983
2514PhosphorylationDEEPKPLLCSQYETL
CCCCCCCCCCCEEEC
3.4217081983
2516PhosphorylationEPKPLLCSQYETLSD
CCCCCCCCCEEECCC
35.4517081983
2518PhosphorylationKPLLCSQYETLSDSE
CCCCCCCEEECCCCC
8.4522210691
2520PhosphorylationLLCSQYETLSDSE--
CCCCCEEECCCCC--
26.9918669648
2522PhosphorylationCSQYETLSDSE----
CCCEEECCCCC----
46.6525159151
2524PhosphorylationQYETLSDSE------
CEEECCCCC------
41.6625159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
1383TPhosphorylationKinaseSIKP57059
PSP
2407SPhosphorylationKinaseCHUKO15111
GPS
2410SPhosphorylationKinaseIKKAO15111
PhosphoELM
2418SPhosphorylationKinaseIKK-FAMILY-GPS
2426SPhosphorylationKinaseCAMK2AQ9UQM7
PSP
2453SPhosphorylationKinaseCAMK2AQ9UQM7
PSP
2511SPhosphorylationKinaseCSNK2A1P68400
GPS

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NCOR2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NCOR2_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MINT_HUMANSPENphysical
11331609
ZBT16_HUMANZBTB16physical
14982881
ANDR_HUMANARphysical
11923464
MTG8_HUMANRUNX1T1physical
14982881
HDAC3_HUMANHDAC3physical
14527417
TF65_HUMANRELAphysical
12589049
IKBA_HUMANNFKBIAphysical
12589049
HDAC3_HUMANHDAC3physical
10809664
HDAC3_HUMANHDAC3physical
11804585
HDAC3_HUMANHDAC3physical
12502735
HDAC1_HUMANHDAC1physical
11739383
HDA10_HUMANHDAC10physical
11739383
PPARD_HUMANPPARDphysical
11867749
NCOR1_HUMANNCOR1physical
10944117
HDAC3_HUMANHDAC3physical
10944117
SMCA4_HUMANSMARCA4physical
10944117
SIN3A_HUMANSIN3Aphysical
10944117
TBL1X_HUMANTBL1Xphysical
10944117
HDAC1_HUMANHDAC1physical
11013263
HDAC2_HUMANHDAC2physical
11013263
SAP30_HUMANSAP30physical
11013263
HDAC3_HUMANHDAC3physical
11013263
TBL1X_HUMANTBL1Xphysical
10809664
HDAC7_MOUSEHdac7physical
10640276
SIN3A_HUMANSIN3Aphysical
10640275
HDAC5_HUMANHDAC5physical
10640275
HDAC4_HUMANHDAC4physical
10640275
RARA_HUMANRARAphysical
11929748
FOS_HUMANFOSphysical
10777532
JUN_HUMANJUNphysical
10777532
TF65_HUMANRELAphysical
10777532
SRF_HUMANSRFphysical
10777532
PML_HUMANPMLphysical
11585900
RARA_HUMANRARAphysical
9256429
ZBT16_HUMANZBTB16physical
9256429
VDR_HUMANVDRphysical
12460926
NR4A1_HUMANNR4A1physical
11559707
PRGR_HUMANPGRphysical
10757795
THB_HUMANTHRBphysical
9878542
RXRA_HUMANRXRAphysical
9878542
VDR_HUMANVDRphysical
9878542
THB_HUMANTHRBphysical
19211732
EP300_HUMANEP300physical
17073437
CBP_HUMANCREBBPphysical
17073437
PO2F1_HUMANPOU2F1physical
19617623
AKT1_HUMANAKT1physical
16613989
HDAC3_HUMANHDAC3physical
16481466
HDAC1_HUMANHDAC1physical
16481466
HDAC2_HUMANHDAC2physical
16481466
BCL6_HUMANBCL6physical
14690607
TF65_HUMANRELAphysical
16382138
PRGR_HUMANPGRphysical
12771131
NR1I2_HUMANNR1I2physical
16144941
HNF4A_HUMANHNF4Aphysical
12205093
HDAC3_HUMANHDAC3physical
12205093
HDAC4_HUMANHDAC4physical
12205093
ATX1_HUMANATXN1physical
16121196
ATX1L_HUMANATXN1Lphysical
16121196
ZBT16_HUMANZBTB16physical
11865059
ZBT16_HUMANZBTB16physical
16024608
SF01_HUMANSF1physical
16002533
NR4A1_HUMANNR4A1physical
16002533
GCR_HUMANNR3C1physical
15870285
CEBPB_HUMANCEBPBphysical
15870285
NF2L2_HUMANNFE2L2physical
15870285
HDAC3_HUMANHDAC3physical
15837933
PPARG_HUMANPPARGphysical
15681609
IKBA_HUMANNFKBIAphysical
15536134
RARA_HUMANRARAphysical
10082574
RXRA_HUMANRXRAphysical
10082574
SKIL_HUMANSKILphysical
10049357
MTG8_HUMANRUNX1T1physical
9819405
GCR_RATNr3c1physical
15016838
RXRA_HUMANRXRAphysical
9415406
RARA_HUMANRARAphysical
9415406
RARA_HUMANRARAphysical
17475621
ESR1_HUMANESR1physical
14715875
ESR2_HUMANESR2physical
14715875
BACH2_HUMANBACH2physical
17383980
NCOA3_HUMANNCOA3physical
20392877
ESR1_HUMANESR1physical
20392877
GPS2_HUMANGPS2physical
21240272
TBL1X_HUMANTBL1Xphysical
21240272
SUMO1_HUMANSUMO1physical
20555024
IRF5_HUMANIRF5physical
20935208
CDN1A_HUMANCDKN1Aphysical
21088000
RXRA_HUMANRXRAphysical
15604093
RARA_HUMANRARAphysical
15604093
RARB_HUMANRARBphysical
15604093
RARG_HUMANRARGphysical
15604093
AP2M1_HUMANAP2M1physical
15604093
RANB9_HUMANRANBP9physical
15604093
RXRG_HUMANRXRGphysical
15604093
NR1H2_HUMANNR1H2physical
15604093
MINT_HUMANSPENphysical
15604093
TNIP2_HUMANTNIP2physical
15604093
PPARG_HUMANPPARGphysical
15604093
PPARG_HUMANPPARGphysical
20364085
ZBT7A_HUMANZBTB7Aphysical
20812024
ANDR_HUMANARphysical
20812024
E2F4_HUMANE2F4physical
22508987
ANDR_HUMANARphysical
22508987
FBW1A_HUMANBTRCphysical
23861398
BCOR_HUMANBCORphysical
23911289
HMGA1_HUMANHMGA1physical
22207709
PPARG_HUMANPPARGphysical
17704298
PPARG_HUMANPPARGphysical
17312272
KLF5_HUMANKLF5physical
18500350
AHR_HUMANAHRphysical
15325265
BCL6_HUMANBCL6physical
26728228

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NCOR2_HUMAN

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Related Literatures of Post-Translational Modification
Acetylation
ReferencePubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-878; LYS-959; LYS-1218;LYS-1248; LYS-1795; LYS-1970 AND LYS-2037, AND MASS SPECTROMETRY.
Phosphorylation
ReferencePubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-67; SER-149; SER-152;THR-553; SER-554; SER-939; SER-1331; SER-2057; SER-2065; SER-2068;SER-2069; SER-2234 AND SER-2269, AND MASS SPECTROMETRY.
"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149; SER-152; THR-156;SER-745; SER-746; SER-750; SER-753; SER-956; SER-1259; THR-1391;SER-1487; TYR-2051; SER-2057; SER-2065; SER-2071; THR-2073; SER-2234AND SER-2269, AND MASS SPECTROMETRY.
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-54, AND MASSSPECTROMETRY.
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-956, AND MASSSPECTROMETRY.
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149; SER-152; SER-215;SER-1261; THR-1391; SER-1584; SER-2016; SER-2057; SER-2054; SER-2069;SER-2205; SER-2208; SER-2269; SER-2522 AND SER-2524, AND MASSSPECTROMETRY.
"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1982 AND SER-2269, ANDMASS SPECTROMETRY.
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1391, AND MASSSPECTROMETRY.

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