| UniProt ID | HXD9_HUMAN | |
|---|---|---|
| UniProt AC | P28356 | |
| Protein Name | Homeobox protein Hox-D9 | |
| Gene Name | HOXD9 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 352 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.. | |
| Protein Sequence | MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MLGGSAGRLKMS ---CCCCCCCEEEEC | 26.25 | 26270265 | |
| 136 | Phosphorylation | GAGGGGGGGGGGPGR CCCCCCCCCCCCCCC | 34.54 | 18669648 | |
| 146 | Phosphorylation | GGPGRGPSPGPSGPA CCCCCCCCCCCCCCC | 45.36 | 30266825 | |
| 150 | Phosphorylation | RGPSPGPSGPANGRH CCCCCCCCCCCCCCC | 64.42 | 30266825 | |
| 161 | Acetylation | NGRHYGIKPETRAAP CCCCCCCCCCCCCCC | 32.22 | 26051181 | |
| 172 | O-linked_Glycosylation | RAAPAPATAASTTSS CCCCCCCCCCCCCCC | 23.00 | 30379171 | |
| 187 | Phosphorylation | SSTSLSSSSKRTECS CCCCCCCCCCCCEEE | 36.18 | 28555341 | |
| 189 | Acetylation | TSLSSSSKRTECSVA CCCCCCCCCCEEEHH | 66.35 | 26051181 | |
| 194 | Phosphorylation | SSKRTECSVARESQG CCCCCEEEHHHHCCC | 16.75 | - | |
| 199 | Phosphorylation | ECSVARESQGSSGPE EEEHHHHCCCCCCCC | 34.00 | 25159151 | |
| 202 | Phosphorylation | VARESQGSSGPEFSC HHHHCCCCCCCCCCH | 25.20 | 25159151 | |
| 203 | Phosphorylation | ARESQGSSGPEFSCN HHHCCCCCCCCCCHH | 66.25 | 25159151 | |
| 292 | Phosphorylation | TRKKRCPYTKYQTLE CCCCCCCCCCCEEEH | 21.35 | 28634298 | |
| 293 | Phosphorylation | RKKRCPYTKYQTLEL CCCCCCCCCCEEEHH | 14.39 | 28634298 | |
| 295 | Phosphorylation | KRCPYTKYQTLELEK CCCCCCCCEEEHHHH | 10.03 | 28634298 | |
| 297 | Phosphorylation | CPYTKYQTLELEKEF CCCCCCEEEHHHHHH | 21.07 | 28634298 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HXD9_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HXD9_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HXD9_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| FAIM3_HUMAN | FAIM3 | physical | 20211142 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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