dbPTM

KLK9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KLK9_HUMAN
UniProt AC	Q9UKQ9
Protein Name	Kallikrein-9
Gene Name	KLK9
Organism	Homo sapiens (Human).
Sequence Length	250
Subcellular Localization	Secreted .
Protein Description
Protein Sequence	MKLGLLCALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIMEN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	TRLFCGATLISDRWL HHHHHCCEEECHHHH	15.20	24732914
54	Phosphorylation	FCGATLISDRWLLTA HHCCEEECHHHHHHH	25.00	24732914
104	Phosphorylation	PGFNKDLSANDHNDD CCCCCCCCCCCCCCC	34.85	20068231
124	Phosphorylation	LPRQARLSPAVQPLN CCCCCCCCCCCCCCC	12.78	-
131	N-linked_Glycosylation	SPAVQPLNLSQTCVS CCCCCCCCHHHCCCC	44.31	UniProtKB CARBOHYD
146	Phosphorylation	PGMQCLISGWGAVSS CCCEEEECCCCCCCC	18.62	-
152	Phosphorylation	ISGWGAVSSPKALFP ECCCCCCCCCHHHCE	40.15	-
153	Phosphorylation	SGWGAVSSPKALFPV CCCCCCCCCHHHCEE	24.66	-
166	N-linked_Glycosylation	PVTLQCANISILENK EEEEEECCEEHHHCC	35.85	UniProtKB CARBOHYD
184	Phosphorylation	WAYPGHISDSMLCAG CCCCCCCCHHHCCCC	20.25	21601212
211	N-linked_Glycosylation	SGGPLVCNGTLAGVV CCCCEEECCEEEEEE	38.72	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KLK9_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KLK9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KLK9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KLK9_HUMAN

Related Literatures of Post-Translational Modification