| UniProt ID | KMT2D_HUMAN | |
|---|---|---|
| UniProt AC | O14686 | |
| Protein Name | Histone-lysine N-methyltransferase 2D | |
| Gene Name | KMT2D | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 5537 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.. | |
| Protein Sequence | MDSQKLAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPRLQETPQDCSGGPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGSPGPNEAVLPSEDLSQIGFPEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGPCASLVTCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYVVKPVAPVAPPELVPMKVKEPEPQYFRFEGVWLTETGMALLRNLTMSPLHKRRQRRGRLGLPGEAGLEGSEPSDALGPDDKKDGDLDTDELLKGEGGVEHMECEIKLEGPVSPDVEPGKEETEESKKRKRKPYRPGIGGFMVRQRKSHTRTKKGPAAQAEVLSGDGQPDEVIPADLPAEGAVEQSLAEGDEKKKQQRRGRKKSKLEDMFPAYLQEAFFGKELLDLSRKALFAVGVGRPSFGLGTPKAKGDGGSERKELPTSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHKIKGPCEQELSSFAVFRRVYIERDEVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLRTNNRRCCYRCSIGENNGRPEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCARSEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 13 | Phosphorylation | LAGEDKDSEPAADGP CCCCCCCCCCCCCCC | 23927012 | ||
| 23 | Phosphorylation | AADGPAASEDPSATE CCCCCCCCCCCCCCC | 30108239 | ||
| 27 | Phosphorylation | PAASEDPSATESDLP CCCCCCCCCCCCCCC | 23927012 | ||
| 29 | Phosphorylation | ASEDPSATESDLPNP CCCCCCCCCCCCCCC | 23927012 | ||
| 31 | Phosphorylation | EDPSATESDLPNPHV CCCCCCCCCCCCCCC | 23927012 | ||
| 42 | Phosphorylation | NPHVGEVSVLSSGSP CCCCCEEEEECCCCC | 23927012 | ||
| 45 | Phosphorylation | VGEVSVLSSGSPRLQ CCEEEEECCCCCCCC | 30278072 | ||
| 46 | Phosphorylation | GEVSVLSSGSPRLQE CEEEEECCCCCCCCC | 30278072 | ||
| 48 | Phosphorylation | VSVLSSGSPRLQETP EEEECCCCCCCCCCC | 30278072 | ||
| 54 | Phosphorylation | GSPRLQETPQDCSGG CCCCCCCCCCCCCCC | 21815630 | ||
| 59 | Phosphorylation | QETPQDCSGGPVRRC CCCCCCCCCCCCCCE | 26074081 | ||
| 75 | Phosphorylation | LCNCGEPSLHGQREL ECCCCCCCCCCCCCH | 26074081 | ||
| 98 | Phosphorylation | WPRCPVVSPGGSPGP CCCCCEECCCCCCCC | 26074081 | ||
| 102 | Phosphorylation | PVVSPGGSPGPNEAV CEECCCCCCCCCCCC | 26074081 | ||
| 112 | Phosphorylation | PNEAVLPSEDLSQIG CCCCCCCCHHHHHCC | 26074081 | ||
| 223 | Phosphorylation | EHSEGAAYLEEARCA CCCHHHHHHHHHCHH | - | ||
| 298 | Phosphorylation | CETCDKGYHTFCLKP EECCCCCCEEEEECC | - | ||
| 314 | Phosphorylation | MEELPAHSWKCKACR HHHCCCCCCCCCHHH | - | ||
| 360 | Phosphorylation | QGGQTIRSVAEQHTP CCCCCHHHHHHHCCC | 30576142 | ||
| 366 | Phosphorylation | RSVAEQHTPVCSRFS HHHHHHCCCCCCCCC | 30576142 | ||
| 370 | Phosphorylation | EQHTPVCSRFSPPEP HHCCCCCCCCCCCCC | 30576142 | ||
| 373 | Phosphorylation | TPVCSRFSPPEPGDT CCCCCCCCCCCCCCC | 30266825 | ||
| 380 | Phosphorylation | SPPEPGDTPTDEPDA CCCCCCCCCCCCCCC | 30266825 | ||
| 382 | Phosphorylation | PEPGDTPTDEPDALY CCCCCCCCCCCCCEE | 30266825 | ||
| 389 | Phosphorylation | TDEPDALYVACQGQP CCCCCCEEEEECCCC | 28796482 | ||
| 389 (in isoform 3) | Phosphorylation | - | 27642862 | ||
| 417 | Acetylation | GPLQCEAKPLGKAGV CCCCEEEEECCCCCC | 26051181 | ||
| 465 | Phosphorylation | TSPPPEASRLSPPPE CCCCCCHHHCCCCCH | 26074081 | ||
| 468 | Phosphorylation | PPEASRLSPPPEELP CCCHHHCCCCCHHCC | 23663014 | ||
| 477 | Phosphorylation | PPEELPASPLPEALH CCHHCCCCCCCHHHH | 23663014 | ||
| 486 | Phosphorylation | LPEALHLSRPLEESP CCHHHHCCCCCCCCC | 23663014 | ||
| 579 | Phosphorylation | LSPPPEESPMSPPPE CCCCCCCCCCCCCCC | 28985074 | ||
| 582 | Phosphorylation | PPEESPMSPPPEESP CCCCCCCCCCCCCCC | 23322592 | ||
| 588 | Phosphorylation | MSPPPEESPMSPPPE CCCCCCCCCCCCCCH | 24275569 | ||
| 591 | Phosphorylation | PPEESPMSPPPEASR CCCCCCCCCCCHHHH | 28985074 | ||
| 597 | Phosphorylation | MSPPPEASRLFPPFE CCCCCHHHHCCCCCC | 23322592 | ||
| 606 | Phosphorylation | LFPPFEESPLSPPPE CCCCCCCCCCCCCCC | 27732954 | ||
| 609 | Phosphorylation | PFEESPLSPPPEESP CCCCCCCCCCCCCCC | 27732954 | ||
| 615 | Phosphorylation | LSPPPEESPLSPPPE CCCCCCCCCCCCCCC | 27732954 | ||
| 618 | Phosphorylation | PPEESPLSPPPEASR CCCCCCCCCCCCHHH | 27732954 | ||
| 624 | Phosphorylation | LSPPPEASRLSPPPE CCCCCCHHHCCCCCC | 27732954 | ||
| 627 | Phosphorylation | PPEASRLSPPPEDSP CCCHHHCCCCCCCCC | 27732954 | ||
| 633 | Phosphorylation | LSPPPEDSPMSPPPE CCCCCCCCCCCCCCC | 27732954 | ||
| 636 | Phosphorylation | PPEDSPMSPPPEESP CCCCCCCCCCCCCCC | 27732954 | ||
| 642 | Phosphorylation | MSPPPEESPMSPPPE CCCCCCCCCCCCCCC | 23403867 | ||
| 645 | Phosphorylation | PPEESPMSPPPEVSR CCCCCCCCCCCCHHH | 27732954 | ||
| 651 | Phosphorylation | MSPPPEVSRLSPLPV CCCCCCHHHCCCCCC | 27732954 | ||
| 654 | Phosphorylation | PPEVSRLSPLPVVSR CCCHHHCCCCCCCCC | 30266825 | ||
| 660 | Phosphorylation | LSPLPVVSRLSPPPE CCCCCCCCCCCCCCC | 23403867 | ||
| 663 | Phosphorylation | LPVVSRLSPPPEESP CCCCCCCCCCCCCCC | 27732954 | ||
| 669 | Phosphorylation | LSPPPEESPLSPPPE CCCCCCCCCCCCCCC | 27732954 | ||
| 672 | Phosphorylation | PPEESPLSPPPEESP CCCCCCCCCCCCCCC | 27732954 | ||
| 678 | Phosphorylation | LSPPPEESPTSPPPE CCCCCCCCCCCCCCC | 27732954 | ||
| 680 | Phosphorylation | PPPEESPTSPPPEAS CCCCCCCCCCCCCHH | 27732954 | ||
| 681 | Phosphorylation | PPEESPTSPPPEASR CCCCCCCCCCCCHHH | 27732954 | ||
| 687 | Phosphorylation | TSPPPEASRLSPPPE CCCCCCHHHCCCCCC | 27732954 | ||
| 738 | Phosphorylation | EPQLCPRSEGPHLSP CCCCCCCCCCCCCCC | 23663014 | ||
| 744 | Phosphorylation | RSEGPHLSPRPEEPH CCCCCCCCCCCCCCC | 23663014 | ||
| 753 | Phosphorylation | RPEEPHLSPRPEEPH CCCCCCCCCCCCCCC | 23663014 | ||
| 762 | Phosphorylation | RPEEPHLSPQAEEPH CCCCCCCCCCCCCCC | 18669648 | ||
| 952 | Phosphorylation | AAAPPALSPLGELEY CCCCCCCCCCCCEEC | - | ||
| 1037 | Phosphorylation | HSLVPQNSPPSQCSP CCCCCCCCCHHHCCC | 26074081 | ||
| 1040 | Phosphorylation | VPQNSPPSQCSPPAL CCCCCCHHHCCCCCC | 26074081 | ||
| 1043 | Phosphorylation | NSPPSQCSPPALPLS CCCHHHCCCCCCCCC | 26074081 | ||
| 1065 | Phosphorylation | IGKVVGVSDEAELHE CCCEECCCCHHHHHH | 28348404 | ||
| 1143 | Phosphorylation | EPGQTPGSLASELKG CCCCCCCHHHHHHCC | 26074081 | ||
| 1146 | Phosphorylation | QTPGSLASELKGSPV CCCCHHHHHHCCCCC | 26074081 | ||
| 1151 | Phosphorylation | LASELKGSPVLLDPE HHHHHCCCCCCCCHH | 25159151 | ||
| 1164 | Phosphorylation | PEELAPVTPMEVYPE HHHHCCCCCCCCCHH | 22199227 | ||
| 1169 | Phosphorylation | PVTPMEVYPECKQTA CCCCCCCCHHHHHCC | 22199227 | ||
| 1175 | Phosphorylation | VYPECKQTAGQGSPC CCHHHHHCCCCCCCC | 29255136 | ||
| 1180 | Phosphorylation | KQTAGQGSPCEEQEE HHCCCCCCCCCCCCC | 23401153 | ||
| 1195 | Phosphorylation | PRAPVAPTPPTLIKS CCCCCCCCCCCEECH | 25159151 | ||
| 1198 | Phosphorylation | PVAPTPPTLIKSDIV CCCCCCCCEECHHHH | 29978859 | ||
| 1202 | Phosphorylation | TPPTLIKSDIVNEIS CCCCEECHHHHHHHH | 26074081 | ||
| 1245 | Phosphorylation | LSMELGVSTDVSPAR CEEEECCCCCCCCCC | 24275569 | ||
| 1249 | Phosphorylation | LGVSTDVSPARDEGS ECCCCCCCCCCCCCC | 26074081 | ||
| 1261 | Phosphorylation | EGSLRLCTDSLPETD CCCEEECCCCCCCCC | 25159151 | ||
| 1263 | Phosphorylation | SLRLCTDSLPETDDS CEEECCCCCCCCCCC | 25159151 | ||
| 1267 | Phosphorylation | CTDSLPETDDSLLCD CCCCCCCCCCCCEEC | 21712546 | ||
| 1270 | Phosphorylation | SLPETDDSLLCDAGT CCCCCCCCCEECCCC | 21712546 | ||
| 1277 | Phosphorylation | SLLCDAGTAISGGKA CCEECCCCCCCCCCC | 27251275 | ||
| 1280 | Phosphorylation | CDAGTAISGGKAEGE ECCCCCCCCCCCCCC | 26714015 | ||
| 1283 | Acetylation | GTAISGGKAEGEKGR CCCCCCCCCCCCCCC | 26051181 | ||
| 1288 | Acetylation | GGKAEGEKGRRRSSP CCCCCCCCCCCCCCH | 26051181 | ||
| 1293 | Phosphorylation | GEKGRRRSSPARSRI CCCCCCCCCHHHHHH | 24732914 | ||
| 1294 | Phosphorylation | EKGRRRSSPARSRIK CCCCCCCCHHHHHHH | 24732914 | ||
| 1298 | Phosphorylation | RRSSPARSRIKQGRS CCCCHHHHHHHCCCC | 24732914 | ||
| 1305 | Phosphorylation | SRIKQGRSSSFPGRR HHHHCCCCCCCCCCC | 23312004 | ||
| 1306 | Phosphorylation | RIKQGRSSSFPGRRR HHHCCCCCCCCCCCC | 23312004 | ||
| 1307 | Phosphorylation | IKQGRSSSFPGRRRP HHCCCCCCCCCCCCC | 28857561 | ||
| 1331 | Phosphorylation | RGRARLKSTASSIET CCCHHHHHCHHCCEE | 30576142 | ||
| 1332 | Phosphorylation | GRARLKSTASSIETL CCHHHHHCHHCCEEE | 20736484 | ||
| 1334 | Phosphorylation | ARLKSTASSIETLVV HHHHHCHHCCEEEEE | 30576142 | ||
| 1335 | Phosphorylation | RLKSTASSIETLVVA HHHHCHHCCEEEEEE | 20736484 | ||
| 1346 | Phosphorylation | LVVADIDSSPSKEEE EEEEECCCCCCCCHH | 30576142 | ||
| 1463 | Phosphorylation | CLDPPLLTVPKGGWK ECCCCCEECCCCCCC | 24719451 | ||
| 1545 | Phosphorylation | FTEDDVEQAADEGFD CCHHHHHHHHHCCCC | 17525332 | ||
| 1604 | Phosphorylation | MALLRNLTMSPLHKR HHHHHHCCCCHHHHH | 30266825 | ||
| 1606 | Phosphorylation | LLRNLTMSPLHKRRQ HHHHCCCCHHHHHHH | 23401153 | ||
| 1610 | Ubiquitination | LTMSPLHKRRQRRGR CCCCHHHHHHHHCCC | - | ||
| 1629 | Phosphorylation | GEAGLEGSEPSDALG CCCCCCCCCCHHCCC | 30266825 | ||
| 1632 | Phosphorylation | GLEGSEPSDALGPDD CCCCCCCHHCCCCCC | 30266825 | ||
| 1647 | Phosphorylation | KKDGDLDTDELLKGE CCCCCCCHHHHHCCC | 20068231 | ||
| 1671 | Phosphorylation | IKLEGPVSPDVEPGK EEEECCCCCCCCCCC | 29255136 | ||
| 1681 | Phosphorylation | VEPGKEETEESKKRK CCCCCHHCHHHHHHC | 23403867 | ||
| 1684 | Phosphorylation | GKEETEESKKRKRKP CCHHCHHHHHHCCCC | 23403867 | ||
| 1690 | Acetylation | ESKKRKRKPYRPGIG HHHHHCCCCCCCCCC | 26051181 | ||
| 1692 | Phosphorylation | KKRKRKPYRPGIGGF HHHCCCCCCCCCCCC | - | ||
| 1722 | Phosphorylation | AAQAEVLSGDGQPDE HHHHEECCCCCCCCC | 26657352 | ||
| 1762 | Phosphorylation | QRRGRKKSKLEDMFP HHHHHHHHHHHHHHH | 25159151 | ||
| 1785 | Phosphorylation | GKELLDLSRKALFAV CHHHHHHHHHHHHHC | 28509920 | ||
| 1798 | Phosphorylation | AVGVGRPSFGLGTPK HCCCCCCCCCCCCCC | 25159151 | ||
| 1803 | Phosphorylation | RPSFGLGTPKAKGDG CCCCCCCCCCCCCCC | 25159151 | ||
| 1815 | Acetylation | GDGGSERKELPTSQK CCCCCCCCCCCCCCC | 26051181 | ||
| 1819 | Phosphorylation | SERKELPTSQKGDDG CCCCCCCCCCCCCCC | 17525332 | ||
| 1820 | Phosphorylation | ERKELPTSQKGDDGP CCCCCCCCCCCCCCC | 17525332 | ||
| 1822 | Acetylation | KELPTSQKGDDGPDI CCCCCCCCCCCCCCC | 23236377 | ||
| 1834 | Phosphorylation | PDIADEESRGLEGKA CCCCCHHHCCCCCCC | 23401153 | ||
| 1840 | Acetylation | ESRGLEGKADTPGPE HHCCCCCCCCCCCCC | 26051181 | ||
| 1843 | Phosphorylation | GLEGKADTPGPEDGG CCCCCCCCCCCCCCC | 30266825 | ||
| 1854 | Phosphorylation | EDGGVKASPVPSDPE CCCCCCCCCCCCCCC | 30266825 | ||
| 1858 | Phosphorylation | VKASPVPSDPEKPGT CCCCCCCCCCCCCCC | 30266825 | ||
| 1865 | Phosphorylation | SDPEKPGTPGEGMLS CCCCCCCCCCCCCCC | 30266825 | ||
| 1872 | Phosphorylation | TPGEGMLSSDLDRIS CCCCCCCCCCHHHCC | 30266825 | ||
| 1873 | Phosphorylation | PGEGMLSSDLDRIST CCCCCCCCCHHHCCC | 30266825 | ||
| 1879 | Phosphorylation | SSDLDRISTEELPKM CCCHHHCCCCCCCCC | 29978859 | ||
| 1880 | Phosphorylation | SDLDRISTEELPKME CCHHHCCCCCCCCCC | 29978859 | ||
| 1889 | Acetylation | ELPKMESKDLQQLFK CCCCCCCHHHHHHHH | 26051181 | ||
| 1896 | Ubiquitination | KDLQQLFKDVLGSER HHHHHHHHHHHCCHH | - | ||
| 1911 | Phosphorylation | EQHLGCGTPGLEGSR HHHCCCCCCCCCCCC | 23401153 | ||
| 1917 | Phosphorylation | GTPGLEGSRTPLQRP CCCCCCCCCCCCCCC | 29255136 | ||
| 1919 | Phosphorylation | PGLEGSRTPLQRPFL CCCCCCCCCCCCCCC | 29449344 | ||
| 1938 | Phosphorylation | PLGNLPSSSPMDSYP CCCCCCCCCCCCCCC | 27251275 | ||
| 1939 | Phosphorylation | LGNLPSSSPMDSYPG CCCCCCCCCCCCCCC | 27251275 | ||
| 1943 | Phosphorylation | PSSSPMDSYPGLCQS CCCCCCCCCCCCCCC | 27732954 | ||
| 1944 | Phosphorylation | SSSPMDSYPGLCQSP CCCCCCCCCCCCCCC | 27732954 | ||
| 1950 | Phosphorylation | SYPGLCQSPFLDSRE CCCCCCCCCCCCCCC | 27732954 | ||
| 1955 | Phosphorylation | CQSPFLDSRERGGFF CCCCCCCCCCCCCCC | 26074081 | ||
| 1963 | Phosphorylation | RERGGFFSPEPGEPD CCCCCCCCCCCCCCC | 26074081 | ||
| 1965 | Phosphorylation | RGGFFSPEPGEPDSP CCCCCCCCCCCCCCC | 18669648 | ||
| 1971 | Phosphorylation | PEPGEPDSPWTGSGG CCCCCCCCCCCCCCC | 26074081 | ||
| 1985 | Phosphorylation | GTTPSTPTTPTTEGE CCCCCCCCCCCCCCC | 28348404 | ||
| 1986 | Phosphorylation | TTPSTPTTPTTEGEG CCCCCCCCCCCCCCC | 28348404 | ||
| 1999 | Phosphorylation | EGDGLSYNQRSLQRW CCCCCCCCHHHHHHH | 18669648 | ||
| 2021 | Phosphorylation | QLSTISPVLYANINF HHCCCCHHHHCCCCC | 18669648 | ||
| 2023 | Phosphorylation | STISPVLYANINFPN CCCCHHHHCCCCCCC | 18669648 | ||
| 2024 | Phosphorylation | TISPVLYANINFPNL CCCHHHHCCCCCCCC | 18669648 | ||
| 2034 | Phosphorylation | NFPNLKQDYPDWSSR CCCCCCCCCCCHHHH | 18669648 | ||
| 2035 | Phosphorylation | FPNLKQDYPDWSSRC CCCCCCCCCCHHHHH | 30576142 | ||
| 2036 | Phosphorylation | PNLKQDYPDWSSRCK CCCCCCCCCHHHHHH | 18669648 | ||
| 2039 | Phosphorylation | KQDYPDWSSRCKQIM CCCCCCHHHHHHHHH | 30576142 | ||
| 2040 | Phosphorylation | QDYPDWSSRCKQIMK CCCCCHHHHHHHHHH | 30576142 | ||
| 2048 | Phosphorylation | RCKQIMKLWRKVPAA HHHHHHHHHHHCCHH | 18669648 | ||
| 2051 | Acetylation | QIMKLWRKVPAADKA HHHHHHHHCCHHHHC | 25953088 | ||
| 2057 | Acetylation | RKVPAADKAPYLQKA HHCCHHHHCHHHHHH | 26051181 | ||
| 2082 | Phosphorylation | KVQKQAESQINKQTK HHHHHHHHHHHHCCH | 21406692 | ||
| 2088 | Phosphorylation | ESQINKQTKVGDIAR HHHHHHCCHHHHHHH | 21406692 | ||
| 2089 | Acetylation | SQINKQTKVGDIARK HHHHHCCHHHHHHHH | 25953088 | ||
| 2097 | Phosphorylation | VGDIARKTDRPALHL HHHHHHHCCCCCEEE | 28555341 | ||
| 2115 | Phosphorylation | PQPGALGSPPPAAAP CCCCCCCCCCCCCCC | 25921289 | ||
| 2128 | Phosphorylation | APTIFIGSPTTPAGL CCEEEECCCCCCCCC | 25921289 | ||
| 2131 | Phosphorylation | IFIGSPTTPAGLSTS EEECCCCCCCCCCCC | - | ||
| 2136 | Phosphorylation | PTTPAGLSTSADGFL CCCCCCCCCCCCCCC | 25921289 | ||
| 2149 | Phosphorylation | FLKPPAGSVPGPDSP CCCCCCCCCCCCCCC | 28111955 | ||
| 2155 | Phosphorylation | GSVPGPDSPGELFLK CCCCCCCCCCCEECC | 20068231 | ||
| 2199 | Phosphorylation | APPTYPPYPSPTGAP CCCCCCCCCCCCCCC | 27251275 | ||
| 2201 | Phosphorylation | PTYPPYPSPTGAPAQ CCCCCCCCCCCCCCC | 25159151 | ||
| 2203 | Phosphorylation | YPPYPSPTGAPAQPP CCCCCCCCCCCCCCC | 27251275 | ||
| 2215 | Phosphorylation | QPPMLGASSRPGAGQ CCCCCCCCCCCCCCC | 22210691 | ||
| 2228 | Phosphorylation | GQPGEFHTTPPGTPR CCCCCCCCCCCCCCC | 29255136 | ||
| 2229 | Phosphorylation | QPGEFHTTPPGTPRH CCCCCCCCCCCCCCC | 29255136 | ||
| 2233 | Phosphorylation | FHTTPPGTPRHQPST CCCCCCCCCCCCCCC | 29255136 | ||
| 2239 | Phosphorylation | GTPRHQPSTPDPFLK CCCCCCCCCCCCCCC | 30266825 | ||
| 2240 | Phosphorylation | TPRHQPSTPDPFLKP CCCCCCCCCCCCCCC | 23401153 | ||
| 2246 | Acetylation | STPDPFLKPRCPSLD CCCCCCCCCCCCCCC | 19608861 | ||
| 2251 | Phosphorylation | FLKPRCPSLDNLAVP CCCCCCCCCCCCCCC | 30266825 | ||
| 2260 | Phosphorylation | DNLAVPESPGVGGGK CCCCCCCCCCCCCCC | 23401153 | ||
| 2269 | Phosphorylation | GVGGGKASEPLLSPP CCCCCCCCCCCCCCC | 23927012 | ||
| 2274 | Phosphorylation | KASEPLLSPPPFGES CCCCCCCCCCCCCCC | 19664994 | ||
| 2281 | Phosphorylation | SPPPFGESRKALEVK CCCCCCCCCHHHHHH | 23927012 | ||
| 2289 | Acetylation | RKALEVKKEELGASS CHHHHHHHHHHCCCC | 26051181 | ||
| 2295 | Phosphorylation | KKEELGASSPSYGPP HHHHHCCCCCCCCCC | 25159151 | ||
| 2296 | Phosphorylation | KEELGASSPSYGPPN HHHHCCCCCCCCCCC | 23401153 | ||
| 2298 | Phosphorylation | ELGASSPSYGPPNLG HHCCCCCCCCCCCCC | 23401153 | ||
| 2299 | Phosphorylation | LGASSPSYGPPNLGF HCCCCCCCCCCCCCC | 21712546 | ||
| 2309 | Phosphorylation | PNLGFVDSPSSGTHL CCCCCCCCCCCCCCC | 25159151 | ||
| 2311 | Phosphorylation | LGFVDSPSSGTHLGG CCCCCCCCCCCCCCC | 22115753 | ||
| 2312 | Phosphorylation | GFVDSPSSGTHLGGL CCCCCCCCCCCCCCE | 28450419 | ||
| 2314 | Phosphorylation | VDSPSSGTHLGGLEL CCCCCCCCCCCCEEE | 28450419 | ||
| 2323 | Phosphorylation | LGGLELKTPDVFKAP CCCEEECCCCCCCCC | 21815630 | ||
| 2332 | Phosphorylation | DVFKAPLTPRASQVE CCCCCCCCCCHHHCC | 27273156 | ||
| 2336 | Phosphorylation | APLTPRASQVEPQSP CCCCCCHHHCCCCCC | 26074081 | ||
| 2342 | Phosphorylation | ASQVEPQSPGLGLRP HHHCCCCCCCCCCCC | 29255136 | ||
| 2361 | Phosphorylation | PAQALAPSPPSHPDI CHHHCCCCCCCCCCC | 26074081 | ||
| 2364 | Phosphorylation | ALAPSPPSHPDIFRP HCCCCCCCCCCCCCC | 26074081 | ||
| 2402 | O-linked_Glycosylation | CCALPPRSLPSDPFS CCCCCCCCCCCCCCC | 30059200 | ||
| 2402 | Phosphorylation | CCALPPRSLPSDPFS CCCCCCCCCCCCCCC | 21815630 | ||
| 2405 | O-linked_Glycosylation | LPPRSLPSDPFSRVP CCCCCCCCCCCCCCC | 30059200 | ||
| 2414 | Phosphorylation | PFSRVPASPQSQSSS CCCCCCCCCCCCCCC | 27732954 | ||
| 2417 | Phosphorylation | RVPASPQSQSSSQSP CCCCCCCCCCCCCCC | 27732954 | ||
| 2419 | Phosphorylation | PASPQSQSSSQSPLT CCCCCCCCCCCCCCC | 27732954 | ||
| 2420 | Phosphorylation | ASPQSQSSSQSPLTP CCCCCCCCCCCCCCC | 27732954 | ||
| 2421 | Phosphorylation | SPQSQSSSQSPLTPR CCCCCCCCCCCCCCC | 27732954 | ||
| 2423 | Phosphorylation | QSQSSSQSPLTPRPL CCCCCCCCCCCCCCC | 27732954 | ||
| 2426 | Phosphorylation | SSSQSPLTPRPLSAE CCCCCCCCCCCCCHH | - | ||
| 2431 | Phosphorylation | PLTPRPLSAEAFCPS CCCCCCCCHHHCCCC | 27499020 | ||
| 2438 | Phosphorylation | SAEAFCPSPVTPRFQ CHHHCCCCCCCCCCC | 27499020 | ||
| 2446 | Phosphorylation | PVTPRFQSPDPYSRP CCCCCCCCCCCCCCC | 27080861 | ||
| 2450 | Phosphorylation | RFQSPDPYSRPPSRP CCCCCCCCCCCCCCC | 27080861 | ||
| 2451 | Phosphorylation | FQSPDPYSRPPSRPQ CCCCCCCCCCCCCCC | 18669648 | ||
| 2455 | Phosphorylation | DPYSRPPSRPQSRDP CCCCCCCCCCCCCCC | 27080861 | ||
| 2459 | Phosphorylation | RPPSRPQSRDPFAPL CCCCCCCCCCCCCCC | 24719451 | ||
| 2468 | Acetylation | DPFAPLHKPPRPQPP CCCCCCCCCCCCCCC | 23954790 | ||
| 2471 | Methylation | APLHKPPRPQPPEVA CCCCCCCCCCCCCCE | 115483461 | ||
| 2480 | Acetylation | QPPEVAFKAGSLAHT CCCCCEEECCCCCCC | 26051181 | ||
| 2483 | Phosphorylation | EVAFKAGSLAHTSLG CCEEECCCCCCCCCC | 28555341 | ||
| 2487 | Phosphorylation | KAGSLAHTSLGAGGF ECCCCCCCCCCCCCC | 28555341 | ||
| 2488 | Phosphorylation | AGSLAHTSLGAGGFP CCCCCCCCCCCCCCC | 28555341 | ||
| 2509 | Acetylation | PAGELHAKVPSGQPP CCCCCEEECCCCCCC | 26051181 | ||
| 2512 | Phosphorylation | ELHAKVPSGQPPNFV CCEEECCCCCCCCCC | - | ||
| 2535 | Asymmetric dimethylarginine | VGTPSPMRFTFPQAV CCCCCCCEECCCCCC | - | ||
| 2535 | Methylation | VGTPSPMRFTFPQAV CCCCCCCEECCCCCC | - | ||
| 2590 | Phosphorylation | ATGNFHPSGSPLGPS EECCCCCCCCCCCCC | 26074081 | ||
| 2592 | Phosphorylation | GNFHPSGSPLGPSSG CCCCCCCCCCCCCCC | 26074081 | ||
| 2608 | Phosphorylation | TGESYGLSPLRPPSV CCCCCCCCCCCCCCC | 26074081 | ||
| 2614 | Phosphorylation | LSPLRPPSVLPPPAP CCCCCCCCCCCCCCC | 26074081 | ||
| 2636 | Phosphorylation | SHGASQRSGITSPVE CCCCCCCCCCCCCCE | 23403867 | ||
| 2639 | Phosphorylation | ASQRSGITSPVEKRE CCCCCCCCCCCEECC | 30266825 | ||
| 2640 | Phosphorylation | SQRSGITSPVEKRED CCCCCCCCCCEECCC | 23401153 | ||
| 2644 | Acetylation | GITSPVEKREDPGTG CCCCCCEECCCCCCC | 25953088 | ||
| 2650 | Phosphorylation | EKREDPGTGMGSSLA EECCCCCCCCCCCCE | 30576142 | ||
| 2664 | Phosphorylation | ATAELPGTQDPGMSG EEECCCCCCCCCCCC | 30576142 | ||
| 2670 | Phosphorylation | GTQDPGMSGLSQTEL CCCCCCCCCCCHHHH | 30576142 | ||
| 2679 | Acetylation | LSQTELEKQRQRQRL CCHHHHHHHHHHHHH | 26051181 | ||
| 2699 | O-linked_Glycosylation | RQQIQRNTLRQEKET HHHHHHHHHHHHHHH | 30059200 | ||
| 2706 | Phosphorylation | TLRQEKETAAAAAGA HHHHHHHHHHHHCCC | 22199227 | ||
| 2719 | O-linked_Glycosylation | GAVGPPGSWGAEPSS CCCCCCCCCCCCCCC | 30059200 | ||
| 2719 | Phosphorylation | GAVGPPGSWGAEPSS CCCCCCCCCCCCCCC | 29978859 | ||
| 2725 | Phosphorylation | GSWGAEPSSPAFEQL CCCCCCCCCHHHHHH | 23401153 | ||
| 2726 | Phosphorylation | SWGAEPSSPAFEQLS CCCCCCCCHHHHHHH | 25159151 | ||
| 2733 | Phosphorylation | SPAFEQLSRGQTPFA CHHHHHHHCCCCCCC | 22199227 | ||
| 2737 | Phosphorylation | EQLSRGQTPFAGTQD HHHHCCCCCCCCCCC | 20068231 | ||
| 2742 | Phosphorylation | GQTPFAGTQDKSSLV CCCCCCCCCCCHHHC | 30576142 | ||
| 2745 | Acetylation | PFAGTQDKSSLVGLP CCCCCCCCHHHCCCC | 25953088 | ||
| 2746 | Phosphorylation | FAGTQDKSSLVGLPP CCCCCCCHHHCCCCH | 30576142 | ||
| 2747 | Phosphorylation | AGTQDKSSLVGLPPS CCCCCCHHHCCCCHH | 24719451 | ||
| 2754 | Phosphorylation | SLVGLPPSKLSGPIL HHCCCCHHHCCCCCC | 30576142 | ||
| 2755 | Acetylation | LVGLPPSKLSGPILG HCCCCHHHCCCCCCC | 23236377 | ||
| 2765 | Phosphorylation | GPILGPGSFPSDDRL CCCCCCCCCCCCCCC | 24719451 | ||
| 2768 | Phosphorylation | LGPGSFPSDDRLSRP CCCCCCCCCCCCCCC | 24719451 | ||
| 2774 | Methylation | PSDDRLSRPPPPATP CCCCCCCCCCCCCCC | 115483509 | ||
| 2780 | Phosphorylation | SRPPPPATPSSMDVN CCCCCCCCCCCCCCC | 28555341 | ||
| 2783 | Phosphorylation | PPPATPSSMDVNSRQ CCCCCCCCCCCCCCH | 22210691 | ||
| 2836 | Asymmetric dimethylarginine | MRFAMSARFPSTPGP HHHHHHCCCCCCCCH | - | ||
| 2836 | Methylation | MRFAMSARFPSTPGP HHHHHHCCCCCCCCH | - | ||
| 2852 | Phosphorylation | LGRQALGSPLAGIST HHHHHCCCCCCCCCC | 23312004 | ||
| 2855 | Phosphorylation | QALGSPLAGISTRLP HHCCCCCCCCCCCCC | 17081983 | ||
| 2858 | Phosphorylation | GSPLAGISTRLPGPG CCCCCCCCCCCCCCC | 23312004 | ||
| 2859 | Phosphorylation | SPLAGISTRLPGPGE CCCCCCCCCCCCCCC | 23312004 | ||
| 2860 | Methylation | PLAGISTRLPGPGEP CCCCCCCCCCCCCCC | 115483517 | ||
| 2881 | Methylation | PAQFIELRHNVQKGL HHHHHHHHHHHHCCC | 115483525 | ||
| 2886 | Acetylation | ELRHNVQKGLGPGGT HHHHHHHCCCCCCCC | 25953088 | ||
| 2886 | Methylation | ELRHNVQKGLGPGGT HHHHHHHCCCCCCCC | 115483533 | ||
| 2903 | Methylation | PGQGPPQRPRFYPVS CCCCCCCCCCEECCC | 115483469 | ||
| 2905 | Methylation | QGPPQRPRFYPVSED CCCCCCCCEECCCCC | 115483477 | ||
| 2907 | Phosphorylation | PPQRPRFYPVSEDPH CCCCCCEECCCCCHH | 18083107 | ||
| 2915 | Methylation | PVSEDPHRLAPEGLR CCCCCHHHCCCCCCC | 115483485 | ||
| 2922 | Methylation | RLAPEGLRGLAVSGL HCCCCCCCCCHHCCC | 115483493 | ||
| 2922 | Phosphorylation | RLAPEGLRGLAVSGL HCCCCCCCCCHHCCC | 18669648 | ||
| 2924 | Phosphorylation | APEGLRGLAVSGLPP CCCCCCCCHHCCCCC | 18669648 | ||
| 2933 | Acetylation | VSGLPPQKPSAPPAP HCCCCCCCCCCCCCC | 25953088 | ||
| 2949 | Phosphorylation | LNNSLHPTPHTKGPT CCCCCCCCCCCCCCC | 25159151 | ||
| 2956 | Phosphorylation | TPHTKGPTLPTGLEL CCCCCCCCCCCCCHH | 23312004 | ||
| 2959 | Phosphorylation | TKGPTLPTGLELVNR CCCCCCCCCCHHCCC | 26657352 | ||
| 2969 | Phosphorylation | ELVNRPPSSTELGRP HHCCCCCCCCCCCCC | 27732954 | ||
| 2970 | Phosphorylation | LVNRPPSSTELGRPN HCCCCCCCCCCCCCC | 29255136 | ||
| 2971 | Phosphorylation | VNRPPSSTELGRPNP CCCCCCCCCCCCCCC | 29255136 | ||
| 2985 | Acetylation | PLALEAGKLPCEDPE CCHHHCCCCCCCCCC | 26051181 | ||
| 3079 | Acetylation | LVESANEKAEREALL HHHHHCHHHHHHHHH | 19608861 | ||
| 3113 | Phosphorylation | ASEPRLASVLPEVKP CCCCCHHHHCCCCCC | 28555341 | ||
| 3119 | Acetylation | ASVLPEVKPKVEEGG HHHCCCCCCCCCCCC | 23954790 | ||
| 3121 | Acetylation | VLPEVKPKVEEGGRH HCCCCCCCCCCCCCC | 23236377 | ||
| 3130 | Phosphorylation | EEGGRHPSPCQFTIA CCCCCCCCCCCEEEE | 25159151 | ||
| 3135 | Phosphorylation | HPSPCQFTIATPKVE CCCCCCEEEECCCCC | 30266825 | ||
| 3138 | Phosphorylation | PCQFTIATPKVEPAP CCCEEEECCCCCCCC | 25159151 | ||
| 3140 | Acetylation | QFTIATPKVEPAPAA CEEEECCCCCCCCCC | 26051181 | ||
| 3155 | Acetylation | NSLGLGLKPGQSMMG CCCCCCCCCCCCCCC | 23954790 | ||
| 3159 | Phosphorylation | LGLKPGQSMMGSRDT CCCCCCCCCCCCCCC | 28851738 | ||
| 3166 | Phosphorylation | SMMGSRDTRMGTGPF CCCCCCCCCCCCCCC | 22210691 | ||
| 3170 | Phosphorylation | SRDTRMGTGPFSSSG CCCCCCCCCCCCCCC | 28555341 | ||
| 3179 | Phosphorylation | PFSSSGHTAEKASFG CCCCCCCCCCCCCCC | 25159151 | ||
| 3182 | Acetylation | SSGHTAEKASFGATG CCCCCCCCCCCCCCC | 25953088 | ||
| 3184 | Phosphorylation | GHTAEKASFGATGGP CCCCCCCCCCCCCCC | 23663014 | ||
| 3188 | Phosphorylation | EKASFGATGGPPAHL CCCCCCCCCCCCHHH | 23663014 | ||
| 3197 | Phosphorylation | GPPAHLLTPSPLSGP CCCHHHCCCCCCCCC | 25159151 | ||
| 3199 | Phosphorylation | PAHLLTPSPLSGPGG CHHHCCCCCCCCCCC | 30278072 | ||
| 3202 | Phosphorylation | LLTPSPLSGPGGSSL HCCCCCCCCCCCHHH | 30278072 | ||
| 3207 | Phosphorylation | PLSGPGGSSLLEKFE CCCCCCCHHHHHHCE | 23663014 | ||
| 3208 | Phosphorylation | LSGPGGSSLLEKFEL CCCCCCHHHHHHCEE | 23663014 | ||
| 3229 | Phosphorylation | LPGGPAASGDELDKM CCCCCCCCHHHHHHH | 22199227 | ||
| 3238 | Phosphorylation | DELDKMESSLVASEL HHHHHHHHHHHHHHH | 25627689 | ||
| 3239 | Phosphorylation | ELDKMESSLVASELP HHHHHHHHHHHHHHH | 25627689 | ||
| 3243 | Phosphorylation | MESSLVASELPLLIE HHHHHHHHHHHHHHH | 22199227 | ||
| 3433 | Acetylation | KAKMVALKGIKKVMA HHHHHHHHHHHHHHH | 19608861 | ||
| 3436 | Acetylation | MVALKGIKKVMAQGS HHHHHHHHHHHHCCC | 23236377 | ||
| 3443 | Phosphorylation | KKVMAQGSIGVAPGM HHHHHCCCCEECCCC | 23403867 | ||
| 3463 | Phosphorylation | SLLAQRLSGGPSSDL HHHHHHHHCCCCHHH | 30108239 | ||
| 3478 | Phosphorylation | QNHVAAGSGQERSAG HHHHHCCCCCCCCCC | 25332170 | ||
| 3483 | Phosphorylation | AGSGQERSAGDPSQP CCCCCCCCCCCCCCC | 25332170 | ||
| 3562 | Phosphorylation | EFPEADAEKLKLVTE CCCHHHHHHHHHHHH | 18669648 | ||
| 3563 | Acetylation | FPEADAEKLKLVTEQ CCHHHHHHHHHHHHH | 26051181 | ||
| 3573 | Acetylation | LVTEQQSKIQKQLDQ HHHHHHHHHHHHHHH | 25953088 | ||
| 3576 | Acetylation | EQQSKIQKQLDQVRK HHHHHHHHHHHHHHH | 26051181 | ||
| 3614 | Phosphorylation | QQQQQQHSAVLALSP HHHHHHHHHHHHCCC | 28450419 | ||
| 3620 | Phosphorylation | HSAVLALSPSQSPRL HHHHHHCCCCCCHHH | 23401153 | ||
| 3622 | Phosphorylation | AVLALSPSQSPRLLT HHHHCCCCCCHHHHH | 28450419 | ||
| 3624 | Phosphorylation | LALSPSQSPRLLTKL HHCCCCCCHHHHHHC | 21712546 | ||
| 3626 | Methylation | LSPSQSPRLLTKLPG CCCCCCHHHHHHCCC | 115483541 | ||
| 3708 | Phosphorylation | PGNLALRSLGPDSRL CCCHHHHHHCCCHHH | 24825855 | ||
| 3713 | Phosphorylation | LRSLGPDSRLLQERQ HHHHCCCHHHHHHHH | 24825855 | ||
| 3719 | Methylation | DSRLLQERQLQLQQQ CHHHHHHHHHHHHHH | 115483501 | ||
| 3727 | Asymmetric dimethylarginine | QLQLQQQRMQLAQKL HHHHHHHHHHHHHHH | - | ||
| 3727 | Methylation | QLQLQQQRMQLAQKL HHHHHHHHHHHHHHH | 24129315 | ||
| 3832 | Phosphorylation | RQVLMTQSRVLSSPQ HHHEECHHHHHCCHH | - | ||
| 3836 | Phosphorylation | MTQSRVLSSPQLAQQ ECHHHHHCCHHHHHC | 25849741 | ||
| 3837 | Phosphorylation | TQSRVLSSPQLAQQG CHHHHHCCHHHHHCC | 22617229 | ||
| 3851 | Methylation | GQGLMGHRLVTAQQQ CCCCHHHHHHHHHHH | 115483549 | ||
| 3940 | Phosphorylation | QQQQQQQLQQQQQQQ HHHHHHHHHHHHHHH | 18669648 | ||
| 3983 | Phosphorylation | GLLNQSRTLLSPQQQ HHHHHHHHCCCHHHH | 22199227 | ||
| 3986 | Phosphorylation | NQSRTLLSPQQQQQQ HHHHHCCCHHHHHHH | 30576142 | ||
| 4004 | Acetylation | LGPGMPAKPLQHFSS HCCCCCCCCCCCCCC | 23954790 | ||
| 4010 | Phosphorylation | AKPLQHFSSPGALGP CCCCCCCCCCCCCCC | 22199227 | ||
| 4011 | Phosphorylation | KPLQHFSSPGALGPT CCCCCCCCCCCCCCE | 22199227 | ||
| 4190 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 4193 (in isoform 3) | Ubiquitination | - | 21890473 | ||
| 4198 | Asymmetric dimethylarginine | MPTVGQLRAQLQGVL CCCHHHHHHHHHHHH | - | ||
| 4198 | Methylation | MPTVGQLRAQLQGVL CCCHHHHHHHHHHHH | - | ||
| 4212 | Dimethylation | LAKNPQLRHLSPQQQ HHHCHHHHCCCHHHH | - | ||
| 4212 | Methylation | LAKNPQLRHLSPQQQ HHHCHHHHCCCHHHH | 30762621 | ||
| 4215 | Phosphorylation | NPQLRHLSPQQQQQL CHHHHCCCHHHHHHH | 26055452 | ||
| 4297 | Phosphorylation | PAPPGALSTGPVLGP CCCCCCCCCCCCCCC | 29978859 | ||
| 4298 | Phosphorylation | APPGALSTGPVLGPV CCCCCCCCCCCCCCC | 29978859 | ||
| 4308 | Phosphorylation | VLGPVHPTPPPSSPQ CCCCCCCCCCCCCCC | 29978859 | ||
| 4312 | Phosphorylation | VHPTPPPSSPQEPKR CCCCCCCCCCCCCCC | 21130716 | ||
| 4313 | Phosphorylation | HPTPPPSSPQEPKRP CCCCCCCCCCCCCCC | 29978859 | ||
| 4321 | Phosphorylation | PQEPKRPSQLPSPSS CCCCCCCCCCCCCHH | 27732954 | ||
| 4325 | Phosphorylation | KRPSQLPSPSSQLPT CCCCCCCCCHHCCCC | 25849741 | ||
| 4327 | Phosphorylation | PSQLPSPSSQLPTEA CCCCCCCHHCCCCCC | 30108239 | ||
| 4328 | Phosphorylation | SQLPSPSSQLPTEAQ CCCCCCHHCCCCCCC | 30108239 | ||
| 4332 | Phosphorylation | SPSSQLPTEAQLPPT CCHHCCCCCCCCCCC | 27732954 | ||
| 4339 | Phosphorylation | TEAQLPPTHPGTPKP CCCCCCCCCCCCCCC | 26714015 | ||
| 4343 | Phosphorylation | LPPTHPGTPKPQGPT CCCCCCCCCCCCCCC | 26425664 | ||
| 4350 | Phosphorylation | TPKPQGPTLEPPPGR CCCCCCCCCCCCCCC | 26074081 | ||
| 4359 | Phosphorylation | EPPPGRVSPAAAQLA CCCCCCCCHHHHHHH | 29255136 | ||
| 4368 | Phosphorylation | AAAQLADTLFSKGLG HHHHHHHHHHHCCCC | 26074081 | ||
| 4371 | Phosphorylation | QLADTLFSKGLGPWD HHHHHHHHCCCCCCC | 26074081 | ||
| 4430 | Phosphorylation | PCALGAQSVKREANG CCCCCCHHHHHHHCC | 27251275 | ||
| 4432 | Acetylation | ALGAQSVKREANGEP CCCCHHHHHHHCCCC | 25953088 | ||
| 4445 | Phosphorylation | EPIGAPGTSNHLLLA CCCCCCCCCCCEEEE | 23607784 | ||
| 4446 | Phosphorylation | PIGAPGTSNHLLLAG CCCCCCCCCCEEEEC | 23607784 | ||
| 4456 | Phosphorylation | LLLAGPRSEAGHLLL EEEECCHHHHHHHHH | - | ||
| 4463 | Phosphorylation | SEAGHLLLQKLLRAK HHHHHHHHHHHHHCC | 18669648 | ||
| 4465 | Acetylation | AGHLLLQKLLRAKNV HHHHHHHHHHHCCCC | 19608861 | ||
| 4465 | Ubiquitination | AGHLLLQKLLRAKNV HHHHHHHHHHHCCCC | 19608861 | ||
| 4468 (in isoform 3) | Ubiquitination | - | 21890473 | ||
| 4470 | Ubiquitination | LQKLLRAKNVQLSTG HHHHHHCCCCEECCC | - | ||
| 4475 | Phosphorylation | RAKNVQLSTGRGSEG HCCCCEECCCCCCHH | 25137130 | ||
| 4476 | Phosphorylation | AKNVQLSTGRGSEGL CCCCEECCCCCCHHH | 22210691 | ||
| 4480 | Phosphorylation | QLSTGRGSEGLRAEI EECCCCCCHHHHHHH | 22210691 | ||
| 4494 | Acetylation | INGHIDSKLAGLEQK HCCCCCHHHHHHHHH | 23236377 | ||
| 4501 | Ubiquitination | KLAGLEQKLQGTPSN HHHHHHHHHCCCCCC | - | ||
| 4505 | Phosphorylation | LEQKLQGTPSNKEDA HHHHHCCCCCCHHHH | 24719451 | ||
| 4507 | Phosphorylation | QKLQGTPSNKEDAAA HHHCCCCCCHHHHHH | 28122231 | ||
| 4509 | Acetylation | LQGTPSNKEDAAARK HCCCCCCHHHHHHCC | 26051181 | ||
| 4516 | Acetylation | KEDAAARKPLTPKPK HHHHHHCCCCCCCCH | 23749302 | ||
| 4519 | Phosphorylation | AAARKPLTPKPKRVQ HHHCCCCCCCCHHHH | 21857030 | ||
| 4534 | Phosphorylation | KASDRLVSSRKKLRK HHHHHHHHHHHHHHH | 24719451 | ||
| 4547 | Phosphorylation | RKEDGVRASEALLKQ HHHHCCCHHHHHHHH | 18669648 | ||
| 4553 | Ubiquitination | RASEALLKQLKQELS CHHHHHHHHHHHHHC | - | ||
| 4617 | Phosphorylation | LLTKNNLSNPPTPPS HHHHCCCCCCCCCCH | 22777824 | ||
| 4621 | Phosphorylation | NNLSNPPTPPSSLPP CCCCCCCCCCHHCCC | 22777824 | ||
| 4624 | Phosphorylation | SNPPTPPSSLPPTPP CCCCCCCHHCCCCCC | 25159151 | ||
| 4625 | Phosphorylation | NPPTPPSSLPPTPPP CCCCCCHHCCCCCCC | 22777824 | ||
| 4629 | Phosphorylation | PPSSLPPTPPPSVQQ CCHHCCCCCCCCHHH | 22777824 | ||
| 4633 | Phosphorylation | LPPTPPPSVQQKMVN CCCCCCCCHHHHHHC | 24275569 | ||
| 4643 | Phosphorylation | QKMVNGVTPSEELGE HHHHCCCCCHHHHCC | 22199227 | ||
| 4653 | Acetylation | EELGEHPKDAASARD HHHCCCCCHHHHHHH | 23236377 | ||
| 4661 | Phosphorylation | DAASARDSERALRDT HHHHHHHHHHHHCCC | - | ||
| 4672 | Acetylation | LRDTSEVKSLDLLAA HCCCHHCCCHHHHHC | 26051181 | ||
| 4682 | Phosphorylation | DLLAALPTPPHNQTE HHHHCCCCCCCCCCC | 30266825 | ||
| 4688 | Phosphorylation | PTPPHNQTEDVRMES CCCCCCCCCCCCCCC | 30108239 | ||
| 4709 | Phosphorylation | PDSIVPASSPESILG CCCCCCCCCHHHHCC | 27470641 | ||
| 4710 | Phosphorylation | DSIVPASSPESILGE CCCCCCCCHHHHCCC | 27470641 | ||
| 4713 | Phosphorylation | VPASSPESILGEEAP CCCCCHHHHCCCCCC | 27470641 | ||
| 4727 | Phosphorylation | PRFPHLGSGRWEQED CCCCCCCCCCHHHCH | 23186163 | ||
| 4738 | Phosphorylation | EQEDRALSPVIPLIP HHCHHCCCCCCCCCC | 19664994 | ||
| 4756 | Sumoylation | IPVFPDTKPYGALGL CCCCCCCCCCCCCCC | - | ||
| 4756 | Acetylation | IPVFPDTKPYGALGL CCCCCCCCCCCCCCC | 23236377 | ||
| 4756 | Sumoylation | IPVFPDTKPYGALGL CCCCCCCCCCCCCCC | 28112733 | ||
| 4768 | Acetylation | LGLEVPGKLPVTTWE CCCCCCCCCCEEEEE | 25953088 | ||
| 4776 | Acetylation | LPVTTWEKGKGSEVS CCEEEEECCCCCEEE | 19608861 | ||
| 4780 | Phosphorylation | TWEKGKGSEVSVMLT EEECCCCCEEEEEEE | 20068231 | ||
| 4783 | Phosphorylation | KGKGSEVSVMLTVSA CCCCCEEEEEEEEHH | 20068231 | ||
| 4787 | Phosphorylation | SEVSVMLTVSAAAAK CEEEEEEEEHHHHHC | 20068231 | ||
| 4789 | Phosphorylation | VSVMLTVSAAAAKNL EEEEEEEHHHHHCCC | 20068231 | ||
| 4794 | Acetylation | TVSAAAAKNLNGVMV EEHHHHHCCCCCHHH | 45654599 | ||
| 4808 | Phosphorylation | VAVAELLSMKIPNSY HHHHHHHCCCCCCCE | 20068231 | ||
| 4814 | Phosphorylation | LSMKIPNSYEVLFPE HCCCCCCCEEEECCC | 23403867 | ||
| 4815 | Phosphorylation | SMKIPNSYEVLFPES CCCCCCCEEEECCCC | 23403867 | ||
| 4822 | O-linked_Glycosylation | YEVLFPESPARAGTE EEEECCCCCCCCCCC | 30059200 | ||
| 4822 | Phosphorylation | YEVLFPESPARAGTE EEEECCCCCCCCCCC | 29255136 | ||
| 4828 | Phosphorylation | ESPARAGTEPKKGEA CCCCCCCCCCCCCCC | 26074081 | ||
| 4832 | Acetylation | RAGTEPKKGEAEGPG CCCCCCCCCCCCCCC | 26051181 | ||
| 4841 | Acetylation | EAEGPGGKEKGLEGK CCCCCCCCCCCCCCC | 26051181 | ||
| 4849 | Phosphorylation | EKGLEGKSPDTGPDW CCCCCCCCCCCCHHH | 22167270 | ||
| 4852 | Phosphorylation | LEGKSPDTGPDWLKQ CCCCCCCCCHHHHHH | 22167270 | ||
| 4870 | Ubiquitination | VLPGYTLKSQLDILS ECCCCCHHHHHHHHH | - | ||
| 4871 | Phosphorylation | LPGYTLKSQLDILSL CCCCCHHHHHHHHHH | 28348404 | ||
| 4877 | Phosphorylation | KSQLDILSLLKQESP HHHHHHHHHHCCCCC | 24719451 | ||
| 4880 | Sumoylation | LDILSLLKQESPAPE HHHHHHHCCCCCCCC | 28112733 | ||
| 4883 | Phosphorylation | LSLLKQESPAPEPPT HHHHCCCCCCCCCCC | 30108239 | ||
| 4890 | Phosphorylation | SPAPEPPTQHSYTYN CCCCCCCCCCCEEEE | 22199227 | ||
| 4893 | Phosphorylation | PEPPTQHSYTYNVSN CCCCCCCCEEEECCC | 22199227 | ||
| 4894 | Phosphorylation | EPPTQHSYTYNVSNL CCCCCCCEEEECCCC | 22199227 | ||
| 4895 | Phosphorylation | PPTQHSYTYNVSNLD CCCCCCEEEECCCCC | 22199227 | ||
| 4896 | Phosphorylation | PTQHSYTYNVSNLDV CCCCCEEEECCCCCH | 22199227 | ||
| 4899 | Phosphorylation | HSYTYNVSNLDVRQL CCEEEECCCCCHHHC | 22199227 | ||
| 4955 | Phosphorylation | SPLPLASSPESARPK CCCCCCCCCCCCCCC | 24275569 | ||
| 4966 | Dimethylation | ARPKPRARPPEEGED CCCCCCCCCCCCCCC | - | ||
| 4966 | Methylation | ARPKPRARPPEEGED CCCCCCCCCCCCCCC | 10619439 | ||
| 4974 | Phosphorylation | PPEEGEDSRPPRLKK CCCCCCCCCCCCHHH | 28857561 | ||
| 4975 | Dimethylation | PEEGEDSRPPRLKKW CCCCCCCCCCCHHHC | - | ||
| 4975 | Methylation | PEEGEDSRPPRLKKW CCCCCCCCCCCHHHC | 10619457 | ||
| 4978 | Dimethylation | GEDSRPPRLKKWKGV CCCCCCCCHHHCCCC | - | ||
| 4978 | Methylation | GEDSRPPRLKKWKGV CCCCCCCCHHHCCCC | 10619447 | ||
| 4998 | Acetylation | RLLLTIQKGSGRQED HHHHHHCCCCCCCHH | 26051181 | ||
| 5024 | "N6,N6-dimethyllysine" | GTALRPDKVPRDMRR CHHCCCCCCCCCHHH | - | ||
| 5024 | Methylation | GTALRPDKVPRDMRR CHHCCCCCCCCCHHH | 23644510 | ||
| 5147 | Phosphorylation | GPCEQELSSFAVFRR CCCHHHHHHHHHEEE | 28122231 | ||
| 5148 | Phosphorylation | PCEQELSSFAVFRRV CCHHHHHHHHHEEEE | 28122231 | ||
| 5218 | Phosphorylation | EATRIYWSLRTNNRR HHHHHEEECCCCCCC | 24719451 | ||
| 5276 | Acetylation | EPVAAMRKEADMLRL HHHHHHHHHHHHHHH | 19608861 | ||
| 5297 | Phosphorylation | GEELFGLTVHAVLRI CCHHHCCHHHHHHHH | - | ||
| 5341 | Phosphorylation | NPTGCARSEPKILTH CCCCCCCCCCCCCCC | 24719451 | ||
| 5347 | Phosphorylation | RSEPKILTHYKRPHT CCCCCCCCCCCCCCC | 24719451 | ||
| 5349 | Phosphorylation | EPKILTHYKRPHTLN CCCCCCCCCCCCCCC | 24719451 | ||
| 5361 | Phosphorylation | TLNSTSMSKAYQSTF CCCCCCCCHHHHHCC | - | ||
| 5369 | Phosphorylation | KAYQSTFTGETNTPY HHHHHCCCCCCCCCC | 23532336 | ||
| 5374 | Phosphorylation | TFTGETNTPYSKQFV CCCCCCCCCCHHHHH | 25159151 | ||
| 5376 | Phosphorylation | TGETNTPYSKQFVHS CCCCCCCCHHHHHCC | 23532336 | ||
| 5377 | Phosphorylation | GETNTPYSKQFVHSK CCCCCCCHHHHHCCC | 26657352 | ||
| 5378 | Ubiquitination | ETNTPYSKQFVHSKS CCCCCCHHHHHCCCC | - | ||
| 5383 | Phosphorylation | YSKQFVHSKSSQYRR CHHHHHCCCCHHHHH | 24719451 | ||
| 5412 | Phosphorylation | RIQGLGLYAAKDLEK HHCCCCEEEECCHHH | - | ||
| 5498 | Phosphorylation | EDKIIIISSRRIPKG CCCEEEEECCCCCCC | 20068231 | ||
| 5499 | Phosphorylation | DKIIIISSRRIPKGE CCEEEEECCCCCCCC | 20068231 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KMT2D_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KMT2D_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CXXC1_HUMAN | CXXC1 | physical | 18082152 | |
| PAXI1_HUMAN | PAXIP1 | physical | 17925232 | |
| ASH2L_HUMAN | ASH2L | physical | 17925232 | |
| RBBP5_HUMAN | RBBP5 | physical | 17925232 | |
| WDR5_HUMAN | WDR5 | physical | 17925232 | |
| RBBP5_HUMAN | RBBP5 | physical | 16603732 | |
| ASH2L_HUMAN | ASH2L | physical | 16603732 | |
| WDR5_HUMAN | WDR5 | physical | 16603732 | |
| KDM4B_HUMAN | KDM4B | physical | 21502505 | |
| ESR1_HUMAN | ESR1 | physical | 21502505 | |
| WDR5_HUMAN | WDR5 | physical | 22665483 | |
| H32_HUMAN | HIST2H3C | physical | 22266653 | |
| MEN1_HUMAN | MEN1 | physical | 14992727 | |
| KDM6A_HUMAN | KDM6A | physical | 24491801 | |
| ASH2L_HUMAN | ASH2L | physical | 24491801 | |
| RBBP5_HUMAN | RBBP5 | physical | 24491801 | |
| WDR5_HUMAN | WDR5 | physical | 24491801 | |
| RBBP5_HUMAN | RBBP5 | physical | 24081332 | |
| WDR5_HUMAN | WDR5 | physical | 27563068 | |
| RBBP5_HUMAN | RBBP5 | physical | 27563068 | |
| ASH2L_HUMAN | ASH2L | physical | 27563068 | |
| AKT1_HUMAN | AKT1 | physical | 28336670 | |
| ANDR_HUMAN | AR | physical | 22722839 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| 147920 | Kabuki syndrome 1 (KABUK1) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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