dbPTM

TRRAP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TRRAP_HUMAN
UniProt AC	Q9Y4A5
Protein Name	Transformation/transcription domain-associated protein
Gene Name	TRRAP
Organism	Homo sapiens (Human).
Sequence Length	3859
Subcellular Localization	Nucleus .
Protein Description	Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome..
Protein Sequence	MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRFLETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIPENTVPPPEMVGMITTIAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVAEFVPLIMNTIAIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQELVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQTFQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQALDIYQVQIAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGGSNRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPARKTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDSALTKLPCYKSLPSLVPLRIAALNALAACNYLPQSREKIIAALFKALNSTNSELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNESISECGRCPLSPFCQFEEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSTMRLDLQFQAIKIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERHRKENMAATNWKEPKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVDFNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVNSVSSSIKRGLSVDSAQEVKRFRTATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNFLIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQVNYGNICTGLEVLSFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQKMVREHLNPQAASGSTEATSGTSELVMLSLELVKTRLAVMSMEMRKNFIQAILTSLIEKSPDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDETLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKYSETATAIAYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALTEYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEEQQLSFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLGRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQGKPTWSGMHSSSIVTAYENSSQHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAFVATQGA ------CCCCCCCCC	20.94	22223895
15	Phosphorylation	GATVVDQTTLMKKYL CCEEECHHHHHHHHH	19.89	22210691
16	Phosphorylation	ATVVDQTTLMKKYLQ CEEECHHHHHHHHHH	21.15	22210691
19	Ubiquitination	VDQTTLMKKYLQFVA ECHHHHHHHHHHHHH	41.18	-
20	Ubiquitination	DQTTLMKKYLQFVAA CHHHHHHHHHHHHHH	36.91	-
21	Phosphorylation	QTTLMKKYLQFVAAL HHHHHHHHHHHHHHH	10.54	22210691
71	Phosphorylation	HIIPRFLTFLQDGEV HHHHHHHHHHHCCCC	21.42	30622161
84	Ubiquitination	EVQFLQEKPAQQLRK CCCCCCCCHHHHHHH	32.46	22817900
84 (in isoform 1)	Ubiquitination	-	32.46	21890473
84 (in isoform 2)	Ubiquitination	-	32.46	21890473
163	Ubiquitination	DFVKQIYKELPKVVN HHHHHHHHHHHHHHH	55.17	29967540
167	Ubiquitination	QIYKELPKVVNRYFE HHHHHHHHHHHHHCC	72.01	29967540
207	Phosphorylation	VNPEREDSETRTHSI CCCCCCCCCCCCCCC	35.79	23917254
209	Phosphorylation	PEREDSETRTHSIIP CCCCCCCCCCCCCCC	44.83	-
211	Phosphorylation	REDSETRTHSIIPRG CCCCCCCCCCCCCCC	27.65	-
213	Phosphorylation	DSETRTHSIIPRGSL CCCCCCCCCCCCCCC	22.92	23917254
219	Phosphorylation	HSIIPRGSLSLKVLA CCCCCCCCCHHHHHH	18.96	24719451
221	Phosphorylation	IIPRGSLSLKVLAEL CCCCCCCHHHHHHHC	28.04	24719451
221 (in isoform 2)	Phosphorylation	-	28.04	24719451
318	Phosphorylation	KGMLQLLSNCPAETA HHHHHHHHCCCHHHH	45.00	-
324	Phosphorylation	LSNCPAETAHLRKEL HHCCCHHHHHHHHHH	22.83	-
329	Ubiquitination	AETAHLRKELLIAAK HHHHHHHHHHHHHHH	60.10	29901268
336	Acetylation	KELLIAAKHILTTEL HHHHHHHHHHHCHHH	23.35	26051181
353	Ubiquitination	QFIPCMDKLFDESIL CCCHHHHHHCCCCEE	24.95	-
434	Phosphorylation	VDCIRSKSEQESGNG HHHHHCCCHHHCCCH	45.84	-
458	Phosphorylation	VFVLKFHTIARYQLS HHHHHHHHHHHHHHH	21.33	20068231
470	Ubiquitination	QLSAIFKKCKPQSEL HHHHHHHHCCCHHHH	36.42	-
538	Ubiquitination	GEKDKEDKQTFQVTD CCCCCCCCCCEEHHH	52.94	29967540
544	Phosphorylation	DKQTFQVTDCRSLVK CCCCEEHHHHHHHHH	20.71	24719451
544 (in isoform 2)	Phosphorylation	-	20.71	24719451
548	Phosphorylation	FQVTDCRSLVKTLVC EEHHHHHHHHHHHHC	43.79	29083192
551	Acetylation	TDCRSLVKTLVCGVK HHHHHHHHHHHCCCE	41.24	26051181
551	Ubiquitination	TDCRSLVKTLVCGVK HHHHHHHHHHHCCCE	41.24	-
552	Phosphorylation	DCRSLVKTLVCGVKT HHHHHHHHHHCCCEE	19.55	29083192
559	Phosphorylation	TLVCGVKTITWGITS HHHCCCEEEEECCCC	22.64	29083192
561	Phosphorylation	VCGVKTITWGITSCK HCCCEEEEECCCCCC	23.91	29083192
565	Phosphorylation	KTITWGITSCKAPGE EEEEECCCCCCCCCC	24.92	29083192
566	Phosphorylation	TITWGITSCKAPGEA EEEECCCCCCCCCCC	16.23	29083192
568	Ubiquitination	TWGITSCKAPGEAQF EECCCCCCCCCCCCC	58.33	-
579	Ubiquitination	EAQFIPNKQLQPKET CCCCCCCCCCCCCCH	47.21	21906983
579 (in isoform 1)	Ubiquitination	-	47.21	21890473
579 (in isoform 2)	Ubiquitination	-	47.21	21890473
584	Ubiquitination	PNKQLQPKETQIYIK CCCCCCCCCHHHHHH	61.50	22817900
586	Phosphorylation	KQLQPKETQIYIKLV CCCCCCCHHHHHHHH	26.79	26552605
589	Phosphorylation	QPKETQIYIKLVKYA CCCCHHHHHHHHHHH	5.12	26552605
595	Phosphorylation	IYIKLVKYAMQALDI HHHHHHHHHHHHCCE	10.38	26552605
603	Phosphorylation	AMQALDIYQVQIAGN HHHHCCEEEEEECCC	11.42	26552605
613	Phosphorylation	QIAGNGQTYIRVANC EECCCCCEEEEEECC	23.47	26552605
614	Phosphorylation	IAGNGQTYIRVANCQ ECCCCCEEEEEECCC	4.46	26552605
663	Phosphorylation	PYMVERISKNYALQI HHHHHHHCCCHHHHH	22.52	-
744	Sulfoxidation	HKIVNSSMELAQTAK HHHHHHHHHHHHHCC	4.99	21406390
818	Phosphorylation	LTVPVRLSSLLPYLP HCCCCHHHHHHHHHH	14.36	24043423
819	Phosphorylation	TVPVRLSSLLPYLPM CCCCHHHHHHHHHHH	38.22	24043423
823	Phosphorylation	RLSSLLPYLPMLMDP HHHHHHHHHHHHHHH	24.33	24043423
833	Phosphorylation	MLMDPLVSALNGSQT HHHHHHHHHHCCCHH	34.42	24043423
838	Phosphorylation	LVSALNGSQTLVSQG HHHHHCCCHHHHHCC	20.93	24043423
840	Phosphorylation	SALNGSQTLVSQGLR HHHCCCHHHHHCCCC	30.72	24043423
843	Phosphorylation	NGSQTLVSQGLRTLE CCCHHHHHCCCCHHH	22.95	24043423
862	Phosphorylation	NLQPDFLYDHIQPVR HCCCCCHHHCCHHHH	12.88	-
886	Phosphorylation	TLRNPADSISHVAYR HHCCHHHHHHHHHHH	28.26	29759185
888	Phosphorylation	RNPADSISHVAYRVL CCHHHHHHHHHHHHH	18.83	29759185
897	Ubiquitination	VAYRVLGKFGGSNRK HHHHHHHHCCCCCHH	36.35	21890473
897	Ubiquitination	VAYRVLGKFGGSNRK HHHHHHHHCCCCCHH	36.35	27667366
897 (in isoform 1)	Ubiquitination	-	36.35	21890473
897 (in isoform 2)	Ubiquitination	-	36.35	21890473
914	Phosphorylation	KESQKLHYVVTEVQG HHHHHCEEEEEEEEC	13.67	-
917	Phosphorylation	QKLHYVVTEVQGPSI HHCEEEEEEEECCEE	22.01	-
923	Phosphorylation	VTEVQGPSITVEFSD EEEEECCEEEEEECC	37.40	-
929	Phosphorylation	PSITVEFSDCKASLQ CEEEEEECCCCHHCC	28.70	-
934	Phosphorylation	EFSDCKASLQLPMEK EECCCCHHCCCCHHH	11.35	-
941	Ubiquitination	SLQLPMEKAIETALD HCCCCHHHHHHHHHH	48.70	-
951	Ubiquitination	ETALDCLKSANTEPY HHHHHHHHHCCCCHH	54.58	32015554
996	Ubiquitination	AHPNFTEKTIPNVII HCCCCCCCCCCCEEE	49.01	29967540
1007	Phosphorylation	NVIISHRYKAQDTPA CEEEEECCCCCCCCC	12.78	-
1016	Ubiquitination	AQDTPARKTFEQALT CCCCCCHHHHHHHHH	60.72	-
1044	Phosphorylation	SALPFVASLIRHYTM HHHHHHHHHHHHHHH	21.01	-
1139	O-linked_Glycosylation	ACQLPLFSYIVERLC HCCCHHHHHHHHHHH	22.95	30379171
1195	Phosphorylation	LFVMMDLTGEVSNGA HHHHHHHCCCCCHHH	27.34	29083192
1199	Phosphorylation	MDLTGEVSNGAVAMA HHHCCCCCHHHHHHH	25.83	29083192
1208	Phosphorylation	GAVAMAKTTLEQLLM HHHHHHHHHHHHHHH	27.37	21406692
1209	Phosphorylation	AVAMAKTTLEQLLMR HHHHHHHHHHHHHHH	27.82	21406692
1215	Sulfoxidation	TTLEQLLMRCATPLK HHHHHHHHHHCCCCC	4.49	21406390
1222	Ubiquitination	MRCATPLKDEERAEE HHHCCCCCCHHHHHH	65.38	29967540
1236	Ubiquitination	EIVAAQEKSFHHVTH HHHHHHHHHHHHCHH	46.47	29967540
1263	Phosphorylation	VRKQAMHSLQVLAQV HHHHHHHHHHHHHHH	13.86	21406692
1271	Phosphorylation	LQVLAQVTGKSVTVI HHHHHHHHCCEEEEE	27.15	21406692
1357	Ubiquitination	LTKLPCYKSLPSLVP HHCCCCCCCCCCHHH	52.84	-
1385	Ubiquitination	YLPQSREKIIAALFK CCCCCHHHHHHHHHH	38.00	-
1396	Phosphorylation	ALFKALNSTNSELQE HHHHHHHCCCHHHHH	29.80	22210691
1437	Phosphorylation	LLMMLGDYRSLTLNV HHHHHCCHHHCHHHH	10.58	-
1439	Phosphorylation	MMLGDYRSLTLNVVN HHHCCHHHCHHHHHH	21.34	20068231
1441	Phosphorylation	LGDYRSLTLNVVNRL HCCHHHCHHHHHHHH	19.96	20068231
1441 (in isoform 2)	Phosphorylation	-	19.96	-
1458	Phosphorylation	VTRLFPNSFNDKFCD HHHHCCCCCCHHHHH	26.18	-
1534 (in isoform 2)	Phosphorylation	-	34.40	-
1552	Phosphorylation	AMLIEAGSPFREPLI HHHHHCCCCCCHHHH	28.10	20068231
1590	Phosphorylation	QWSRMFMSFLKHKDA HHHHHHHHHHHCCCC	19.03	24719451
1593	Acetylation	RMFMSFLKHKDARPL HHHHHHHHCCCCCCH	46.74	26051181
1610 (in isoform 2)	Phosphorylation	-	26.12	-
1613	Phosphorylation	ANPNRFITLLLPGGA HCCCCEEEEEECCCC	14.51	24732914
1615 (in isoform 2)	Phosphorylation	-	3.98	-
1622	Phosphorylation	LLPGGAQTAVRPGSP EECCCCCEEECCCCC	26.96	25022875
1628	Phosphorylation	QTAVRPGSPSTSTMR CEEECCCCCCCCCEE	20.54	21082442
1630	Phosphorylation	AVRPGSPSTSTMRLD EECCCCCCCCCEEEE	36.37	25022875
1631	Phosphorylation	VRPGSPSTSTMRLDL ECCCCCCCCCEEEEE	31.44	30631047
1632	Phosphorylation	RPGSPSTSTMRLDLQ CCCCCCCCCEEEEEH	25.25	30631047
1633	Phosphorylation	PGSPSTSTMRLDLQF CCCCCCCCEEEEEHH	13.34	21712546
1647	Phosphorylation	FQAIKIISIIVKNDD HCEEEEEEEEECCCC	15.10	20068231
1691	Methylation	NMAATNWKEPKLLAY CCCCCCCCCHHHHHH	67.23	23644510
1731	Ubiquitination	RFLCNMTFLKEYMEE HHHHCCHHHHHHHHH	6.80	27667366
1749	Ubiquitination	KNYSIAQKRALFFRF CCCCHHHHHHHEEEE	30.53	27667366
1751	Ubiquitination	YSIAQKRALFFRFVD CCHHHHHHHEEEECC	18.76	22817900
1751 (in isoform 2)	Ubiquitination	-	18.76	21890473
1753	Ubiquitination	IAQKRALFFRFVDFN HHHHHHHEEEECCCC	3.94	22817900
1769	Ubiquitination	PNFGDELKAKVLQHI CCCCHHHHHHHHHHH	44.08	21906983
1769 (in isoform 1)	Ubiquitination	-	44.08	21890473
1771	Ubiquitination	FGDELKAKVLQHILN CCHHHHHHHHHHHHC	41.72	22817900
1796	Ubiquitination	EGEQLLGPPNPEGDN CCCCCCCCCCCCCCC	26.01	23503661
1796 (in isoform 2)	Ubiquitination	-	26.01	-
1802	Ubiquitination	GPPNPEGDNPESITS CCCCCCCCCCHHCCE	66.89	23503661
1814	Ubiquitination	ITSVFITKVLDPEKQ CCEEEEEECCCHHHH	35.66	23503661
1820	Ubiquitination	TKVLDPEKQADMLDS EECCCHHHHHHHHHH	57.06	23503661
1907	Phosphorylation	IVLQVFHSLLKAHAM HHHHHHHHHHHHHHH	24.75	24719451
1987	Phosphorylation	HLVQHMVSAMQRLGF HHHHHHHHHHHHCCC	15.50	26074081
1995	Phosphorylation	AMQRLGFTPSVTIEQ HHHHCCCCCCCCEEE	16.92	26074081
1997	Phosphorylation	QRLGFTPSVTIEQRR HHCCCCCCCCEEEEE	28.92	26074081
1999	Phosphorylation	LGFTPSVTIEQRRLA CCCCCCCCEEEEECC	24.12	26074081
2004	Ubiquitination	SVTIEQRRLAVDLSE CCCEEEEECCCCHHH	27.05	22817900
2004 (in isoform 2)	Ubiquitination	-	27.05	21890473
2022	Ubiquitination	KWELQRIKDQQPDSD HHHHHHHHCCCCCCC	52.23	21906983
2022 (in isoform 1)	Ubiquitination	-	52.23	21890473
2029	Ubiquitination	KDQQPDSDMDPNSSG HCCCCCCCCCCCCCC	53.54	22817900
2029 (in isoform 2)	Ubiquitination	-	53.54	21890473
2033 (in isoform 2)	Phosphorylation	-	44.54	24719451
2034	Phosphorylation	DSDMDPNSSGEGVNS CCCCCCCCCCCCHHH	45.14	15302935
2035	Phosphorylation	SDMDPNSSGEGVNSV CCCCCCCCCCCHHHH	47.72	28555341
2041	Ubiquitination	SSGEGVNSVSSSIKR CCCCCHHHHHHHHHC	22.44	29967540
2047	Acetylation	NSVSSSIKRGLSVDS HHHHHHHHCCCCCCC	42.22	26051181
2047	Ubiquitination	NSVSSSIKRGLSVDS HHHHHHHHCCCCCCC	42.22	21906983
2047 (in isoform 1)	Ubiquitination	-	42.22	21890473
2051	Phosphorylation	SSIKRGLSVDSAQEV HHHHCCCCCCCHHHH	27.05	29255136
2054	Phosphorylation	KRGLSVDSAQEVKRF HCCCCCCCHHHHHHH	29.69	25159151
2057 (in isoform 2)	Phosphorylation	-	50.12	-
2059	Acetylation	VDSAQEVKRFRTATG CCCHHHHHHHHHHHH	45.10	25953088
2059	Phosphorylation	VDSAQEVKRFRTATG CCCHHHHHHHHHHHH	45.10	32645325
2059	Ubiquitination	VDSAQEVKRFRTATG CCCHHHHHHHHHHHH	45.10	29967540
2059 (in isoform 2)	Phosphorylation	-	45.10	24719451
2063	Phosphorylation	QEVKRFRTATGAISA HHHHHHHHHHHHHHH	26.34	19835603
2065	Phosphorylation	VKRFRTATGAISAVF HHHHHHHHHHHHHHH	26.91	24173317
2069	Phosphorylation	RTATGAISAVFGRSQ HHHHHHHHHHHCCCC	20.18	19835603
2075	Phosphorylation	ISAVFGRSQSLPGAD HHHHHCCCCCCCCCC	25.21	30266825
2077	Phosphorylation	AVFGRSQSLPGADSL HHHCCCCCCCCCCHH	37.47	25159151
2083	Phosphorylation	QSLPGADSLLAKPID CCCCCCCHHCCCCCC	25.42	30266825
2084	Phosphorylation	SLPGADSLLAKPIDK CCCCCCHHCCCCCCC	5.77	32645325
2087	Ubiquitination	GADSLLAKPIDKQHT CCCHHCCCCCCCCCH	42.34	-
2091	Ubiquitination	LLAKPIDKQHTDTVV HCCCCCCCCCHHHHH	44.70	-
2094	Phosphorylation	KPIDKQHTDTVVNFL CCCCCCCHHHHHHHH	30.76	24043423
2096	Phosphorylation	IDKQHTDTVVNFLIR CCCCCHHHHHHHHHH	27.75	24043423
2112	Phosphorylation	ACQVNDNTNTAGSPG HHEECCCCCCCCCHH	36.49	24043423
2114	Phosphorylation	QVNDNTNTAGSPGEV EECCCCCCCCCHHHH	30.29	20068231
2114 (in isoform 2)	Phosphorylation	-	30.29	-
2117	Phosphorylation	DNTNTAGSPGEVLSR CCCCCCCCHHHHHHH	27.54	24043423
2123	Phosphorylation	GSPGEVLSRRCVNLL CCHHHHHHHHHHHHH	23.90	24043423
2123	Ubiquitination	GSPGEVLSRRCVNLL CCHHHHHHHHHHHHH	23.90	29967540
2127	Ubiquitination	EVLSRRCVNLLKTAL HHHHHHHHHHHHHHH	5.54	29967540
2132	Phosphorylation	RCVNLLKTALRPDMW HHHHHHHHHHCCCCC	30.78	20068231
2141	Ubiquitination	LRPDMWPKSELKLQW HCCCCCCHHHHHHHH	40.84	29967540
2145	Ubiquitination	MWPKSELKLQWFDKL CCCHHHHHHHHHHHH	34.28	29967540
2207	Ubiquitination	CMTCGNTKVLRAVHS HHHCCCHHHHHHHHH	43.18	-
2214	Phosphorylation	KVLRAVHSLLSRLMS HHHHHHHHHHHHHHH	25.14	24719451
2217	Phosphorylation	RAVHSLLSRLMSIFP HHHHHHHHHHHHHCC	28.76	24719451
2221	Phosphorylation	SLLSRLMSIFPTEPS HHHHHHHHHCCCCCC	26.18	20071362
2225	Phosphorylation	RLMSIFPTEPSTSSV HHHHHCCCCCCCCHH	50.18	20071362
2228	Phosphorylation	SIFPTEPSTSSVASK HHCCCCCCCCHHHHH	34.39	20071362
2230	Phosphorylation	FPTEPSTSSVASKYE CCCCCCCCHHHHHHH	27.44	20071362
2231	Phosphorylation	PTEPSTSSVASKYEE CCCCCCCHHHHHHHH	23.07	20071362
2234	Phosphorylation	PSTSSVASKYEELEC CCCCHHHHHHHHHHH	33.35	20071362
2235	Acetylation	STSSVASKYEELECL CCCHHHHHHHHHHHH	47.12	69679
2251	Phosphorylation	AAVGKVIYEGLTNYE HHHHHHHHHCCCCHH	13.61	28152594
2284	Phosphorylation	SACSNNPSYIDRLIS HHHCCCHHHHHHHHH	36.52	-
2291	Phosphorylation	SYIDRLISVFMRSLQ HHHHHHHHHHHHHHH	17.56	21406692
2296	Phosphorylation	LISVFMRSLQKMVRE HHHHHHHHHHHHHHH	24.30	21406692
2311	Phosphorylation	HLNPQAASGSTEATS HCCCCCCCCCCCCCC	35.97	22210691
2313	Phosphorylation	NPQAASGSTEATSGT CCCCCCCCCCCCCCC	22.15	22210691
2315 (in isoform 2)	Phosphorylation	-	52.20	-
2333	Phosphorylation	LSLELVKTRLAVMSM HHHHHHHHHHHHHCH	24.36	17192257
2339	Phosphorylation	KTRLAVMSMEMRKNF HHHHHHHCHHHHHHH	12.65	22210691
2339	Ubiquitination	KTRLAVMSMEMRKNF HHHHHHHCHHHHHHH	12.65	23000965
2344	Ubiquitination	VMSMEMRKNFIQAIL HHCHHHHHHHHHHHH	55.70	23000965
2352	Phosphorylation	NFIQAILTSLIEKSP HHHHHHHHHHHHHCC	18.51	20068231
2353	Phosphorylation	FIQAILTSLIEKSPD HHHHHHHHHHHHCCC	24.73	24719451
2357	Ubiquitination	ILTSLIEKSPDAKIL HHHHHHHHCCCHHHH	61.36	23000965
2362	Ubiquitination	IEKSPDAKILRAVVK HHHCCCHHHHHHHHH	50.05	23000965
2369	Ubiquitination	KILRAVVKIVEEWVK HHHHHHHHHHHHHHH	34.14	33845483
2374	Ubiquitination	VVKIVEEWVKNNSPM HHHHHHHHHHCCCCC	7.90	29967540
2383 (in isoform 2)	Phosphorylation	-	11.47	-
2392	Ubiquitination	QTPTLREKSILLVKM CCCCHHHHHHHHHHH	36.04	29967540
2401	Phosphorylation	ILLVKMMTYIEKRFP HHHHHHHHHHHHHCC	20.18	22817900
2402	Phosphorylation	LLVKMMTYIEKRFPE HHHHHHHHHHHHCCC	6.81	20068231
2405	Methylation	KMMTYIEKRFPEDLE HHHHHHHHHCCCCHH	50.18	23644510
2405	Ubiquitination	KMMTYIEKRFPEDLE HHHHHHHHHCCCCHH	50.18	-
2420	Ubiquitination	LNAQFLDLVNYVYRD HHHHHHHHHHHHHCC	2.68	22817900
2420 (in isoform 2)	Ubiquitination	-	2.68	21890473
2438	Ubiquitination	SGSELTAKLEPAFLS CCCHHHHHCHHHHHH	48.42	22817900
2438 (in isoform 1)	Ubiquitination	-	48.42	21890473
2445	Phosphorylation	KLEPAFLSGLRCAQP HCHHHHHHCCCCCHH	29.36	24719451
2457	Ubiquitination	AQPLIRAKFFEVFDN CHHHHHHHHHHHCCC	40.51	-
2520	Phosphorylation	CQGAMLPSITNVINL CCCCCCCCHHCHHHH	37.78	30301811
2522	Phosphorylation	GAMLPSITNVINLAD CCCCCCHHCHHHHCC	27.98	29083192
2525	Acetylation	LPSITNVINLADSHD CCCHHCHHHHCCCCC	3.66	19608861
2525 (in isoform 2)	Acetylation	-	3.66	-
2530	Phosphorylation	NVINLADSHDRAAFA CHHHHCCCCCHHHHH	22.98	21712546
2536 (in isoform 2)	Phosphorylation	-	4.38	24719451
2543	Acetylation	FAMVTHVKQEPRERE HHHHHHHHCCCCCCC	41.14	23954790
2543	Sumoylation	FAMVTHVKQEPRERE HHHHHHHHCCCCCCC	41.14	28112733
2543	Ubiquitination	FAMVTHVKQEPRERE HHHHHHHHCCCCCCC	41.14	19608861
2552	Phosphorylation	EPRERENSESKEEDV CCCCCCCCCCCCCCE	38.19	25849741
2554	Phosphorylation	RERENSESKEEDVEI CCCCCCCCCCCCEEE	45.23	30266825
2564	Ubiquitination	EDVEIDIELAPGDQT CCEEEEEEECCCCCC	34.82	29967540
2571	Phosphorylation	ELAPGDQTSTPKTKE EECCCCCCCCCCCCC	39.03	25159151
2572	Phosphorylation	LAPGDQTSTPKTKEL ECCCCCCCCCCCCCC	36.76	25627689
2573	Phosphorylation	APGDQTSTPKTKELS CCCCCCCCCCCCCCC	31.99	25627689
2579	Ubiquitination	STPKTKELSEKDIGN CCCCCCCCCHHHHHH	9.50	21890473
2579	Ubiquitination	STPKTKELSEKDIGN CCCCCCCCCHHHHHH	9.50	21890473
2579 (in isoform 2)	Ubiquitination	-	9.50	21890473
2582	Acetylation	KTKELSEKDIGNQLH CCCCCCHHHHHHHHH	51.80	25953088
2582	Ubiquitination	KTKELSEKDIGNQLH CCCCCCHHHHHHHHH	51.80	29967540
2583 (in isoform 2)	Phosphorylation	-	50.40	-
2597	Ubiquitination	MLTNRHDKFLDTLRE HHHHCHHHHHHHHHH	41.52	21890473
2597 (in isoform 1)	Ubiquitination	-	41.52	21890473
2601	Phosphorylation	RHDKFLDTLREVKTG CHHHHHHHHHHHHHH	29.84	17192257
2620	Ubiquitination	AFVQLCHISTTLAEK HHHHHHHHHHHHHHH	3.69	21890473
2620	Ubiquitination	AFVQLCHISTTLAEK HHHHHHHHHHHHHHH	3.69	21890473
2620 (in isoform 2)	Ubiquitination	-	3.69	21890473
2638	Ubiquitination	QLFPRLWKILSDRQQ HHHHHHHHHHCHHHH	38.06	21890473
2638 (in isoform 1)	Ubiquitination	-	38.06	21890473
2706	Ubiquitination	THNLWFRSTLMLEHQ CCCCCHHHHHHHHHH	19.20	29967540
2724	Acetylation	KGLSLQIKPKQTTEF CCCCCEECCCCCCCC	32.95	25953088
2724	Ubiquitination	KGLSLQIKPKQTTEF CCCCCEECCCCCCCC	32.95	29967540
2811	Ubiquitination	HERSNASPAIFPEYQ HHHHCCCCCCCCHHH	27.28	29967540
2829	Ubiquitination	DHWIRCSKELNQWEA HHHHHHCHHHHHHHH	70.60	29967540
2950	Ubiquitination	LQEAAQINAGLQPTN HHHHHHHCCCCCCCC	18.84	22817900
2954	Ubiquitination	AQINAGLQPTNLGRN HHHCCCCCCCCCCCC	41.68	21890473
2954	Ubiquitination	AQINAGLQPTNLGRN HHHCCCCCCCCCCCC	41.68	21890473
2954 (in isoform 2)	Ubiquitination	-	41.68	21890473
2968	Ubiquitination	NNSLHDMKTVVKTWR CCCHHHHHHHHHHHH	44.20	22817900
2972	Ubiquitination	HDMKTVVKTWRNRLP HHHHHHHHHHHHCCC	37.73	21890473
2972 (in isoform 1)	Ubiquitination	-	37.73	21890473
3017	Ubiquitination	SSSIVTAYENSSQHD CHHHEEEEECCCCCC	13.28	22817900
3021	Ubiquitination	VTAYENSSQHDPSSN EEEEECCCCCCCCCC	43.02	21890473
3021	Ubiquitination	VTAYENSSQHDPSSN EEEEECCCCCCCCCC	43.02	21890473
3021 (in isoform 2)	Ubiquitination	-	43.02	21890473
3046	Ubiquitination	SAIIQYGKIARKQGL HHHHHHHHHHHHCCH	28.40	22817900
3049	Acetylation	IQYGKIARKQGLVNV HHHHHHHHHCCHHHH	34.99	19608861
3049	Ubiquitination	IQYGKIARKQGLVNV HHHHHHHHHCCHHHH	34.99	19608861
3049 (in isoform 2)	Acetylation	-	34.99	-
3050	Ubiquitination	QYGKIARKQGLVNVA HHHHHHHHCCHHHHH	39.43	21890473
3050 (in isoform 1)	Ubiquitination	-	39.43	21890473
3078	Acetylation	PIVDCFQKIRQQVKC CHHHHHHHHHHHHHH	21.43	19608861
3078	Ubiquitination	PIVDCFQKIRQQVKC CHHHHHHHHHHHHHH	21.43	19608861
3082	Ubiquitination	CFQKIRQQVKCYLQL HHHHHHHHHHHHHHH	27.13	29967540
3111	Ubiquitination	VIESTNLKYFTKEMT EECCCCCHHCCHHHH	40.15	29967540
3122	Phosphorylation	KEMTAEFYALKGMFL HHHHHHHHHHHHHHH	11.52	19835603
3154 (in isoform 2)	Phosphorylation	-	33.77	-
3178	Phosphorylation	RQLHLGVSAITCYLH CCCCCCHHHHHHHHH	16.50	20068231
3181	Phosphorylation	HLGVSAITCYLHACR CCCHHHHHHHHHHHH	8.53	20068231
3183	Phosphorylation	GVSAITCYLHACRHQ CHHHHHHHHHHHHCC	7.90	20068231
3193	Phosphorylation	ACRHQNESKSRKYLA HHHCCCHHHCHHHHH	43.40	20068231
3255	Phosphorylation	KLLLNLISQVGRVYP HHHHHHHHHHCCCCC	23.21	20886841
3286	Phosphorylation	EQRERYKSDPGPIRA HHHHHHCCCCCCCCC	39.85	20860994
3316	Phosphorylation	ELHPTLLSSLEGIVD HHCHHHHHHHHHHHH	35.67	22210691
3317	Phosphorylation	LHPTLLSSLEGIVDQ HCHHHHHHHHHHHHH	30.34	22210691
3343	Ubiquitination	VLRQLQQGLAKCYSV HHHHHHHHHHHHHHH	18.03	22817900
3343 (in isoform 2)	Ubiquitination	-	18.03	21890473
3344	Ubiquitination	LRQLQQGLAKCYSVA HHHHHHHHHHHHHHH	3.42	22817900
3346	Ubiquitination	QLQQGLAKCYSVAFE HHHHHHHHHHHHHHH	38.45	-
3354	Ubiquitination	CYSVAFEKSGAVSDA HHHHHHHCCCCCCCC	47.97	-
3362	Acetylation	SGAVSDAKITPHTLN CCCCCCCCCCHHHHH	52.70	25953088
3362	Ubiquitination	SGAVSDAKITPHTLN CCCCCCCCCCHHHHH	52.70	-
3372	Ubiquitination	PHTLNFVKKLVSTFG HHHHHHHHHHHHHHC	35.93	21906983
3372 (in isoform 1)	Ubiquitination	-	35.93	21890473
3373	Ubiquitination	HTLNFVKKLVSTFGV HHHHHHHHHHHHHCC	49.14	22817900
3376	Phosphorylation	NFVKKLVSTFGVGLE HHHHHHHHHHCCCCC	28.58	20860994
3386	Phosphorylation	GVGLENVSNVSTMFS CCCCCCCCCHHHHHC	42.99	20860994
3386	Ubiquitination	GVGLENVSNVSTMFS CCCCCCCCCHHHHHC	42.99	33845483
3386 (in isoform 2)	Ubiquitination	-	42.99	21890473
3388	Ubiquitination	GLENVSNVSTMFSSA CCCCCCCHHHHHCHH	3.82	22817900
3389	Phosphorylation	LENVSNVSTMFSSAA CCCCCCHHHHHCHHH	20.57	20860994
3390	Phosphorylation	ENVSNVSTMFSSAAS CCCCCHHHHHCHHHH	20.25	20860994
3399	Phosphorylation	FSSAASESLARRAQA HCHHHHHHHHHHHHH	25.49	20860994
3415	Ubiquitination	AQDPVFQKLKGQFTT HCCHHHHHHCCCCCC	40.47	21906983
3415 (in isoform 1)	Ubiquitination	-	40.47	21890473
3417	Ubiquitination	DPVFQKLKGQFTTDF CHHHHHHCCCCCCCC	58.67	22817900
3429	Ubiquitination	TDFDFSVPGSMKLHN CCCCCCCCCHHHHHH	28.13	33845483
3442	Ubiquitination	HNLISKLKKWIKILE HHHHHHHHHHHHHHH	50.20	-
3451	Acetylation	WIKILEAKTKQLPKF HHHHHHHHHCCCCCE	47.05	25953088
3464	Ubiquitination	KFFLIEEKCRFLSNF CEEHHHHHHHHHHCC	20.23	-
3469	Phosphorylation	EEKCRFLSNFSAQTA HHHHHHHHCCCCCCC	32.87	-
3488	Ubiquitination	PGEFLMPKPTHYYIK CCCCCCCCCCEEEEE	48.89	-
3508	Ubiquitination	PRVEIVQKHNTAARR CCEEHHHHCCHHHHH	28.11	-
3526	Phosphorylation	RGHNGKIYPYLVMND ECCCCCEEEEEEECC	6.84	-
3529	Ubiquitination	NGKIYPYLVMNDACL CCCEEEEEEECCCCC	2.26	24816145
3558	Ubiquitination	LLNPCLEKRKETTKR HHHHHHHHCCCCCHH	56.68	24816145
3569	Ubiquitination	TTKRHLFFTVPRVVA CCHHHHEEECCEEEE	9.42	22817900
3569 (in isoform 2)	Ubiquitination	-	9.42	21890473
3574	Ubiquitination	LFFTVPRVVAVSPQM HEEECCEEEEECCCC	2.37	22817900
3575	Ubiquitination	FFTVPRVVAVSPQMR EEECCEEEEECCCCC	4.61	23503661
3598	Acetylation	LSLVEIYKQRCAKKG CHHHHHHHHHHHHCC	36.61	26051181
3598	Ubiquitination	LSLVEIYKQRCAKKG CHHHHHHHHHHHHCC	36.61	21906983
3598 (in isoform 1)	Ubiquitination	-	36.61	21890473
3603	Ubiquitination	IYKQRCAKKGIEHDN HHHHHHHHCCCCCCC	55.98	22817900
3604	Ubiquitination	YKQRCAKKGIEHDNP HHHHHHHCCCCCCCH	46.74	23503661
3610	Ubiquitination	KKGIEHDNPISRYYD HCCCCCCCHHHHHHH	37.40	22817900
3610 (in isoform 2)	Ubiquitination	-	37.40	21890473
3618	Methylation	PISRYYDRLATVQAR HHHHHHHHHHHHHCC	15.31	115919037
3639	Ubiquitination	QVLRDILKEVQSNMV HHHHHHHHHHHHCCC	57.06	22817900
3639 (in isoform 1)	Ubiquitination	-	57.06	21890473
3643	Phosphorylation	DILKEVQSNMVPRSM HHHHHHHHCCCCHHH	31.88	23403867
3709	Phosphorylation	TGKLNVAYFRFDIND HCCCEEEEEEEEECC	7.33	-
3765	Ubiquitination	CFAQPNFKVDGILKT HHCCCCCEECCHHHH	46.16	-
3772	Phosphorylation	KVDGILKTVLRDEII EECCHHHHHHHHHHH	22.71	24719451
3790	Phosphorylation	KKTQEDTSSPLSAAG HCCCCCCCCCCCCCC	42.13	25627689
3791	Phosphorylation	KTQEDTSSPLSAAGQ CCCCCCCCCCCCCCC	31.77	25627689
3805	Ubiquitination	QPENMDSQQLVSLVQ CCCCCCHHHHHHHHH	36.04	32015554
3834	Ubiquitination	QFEGGESKVNTLVAA HHCCCHHHHHHHHHH	34.89	32015554
3848	Ubiquitination	AANSLDNLCRMDPAW HHHCHHHHHCCCCCC	1.63	32015554

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	CDC20	Q12834	PMID:23318449
-	K	Ubiquitination	E3 ubiquitin ligase	FZR1	Q9UM11	PMID:23318449

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TRRAP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TRRAP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EP400_HUMAN	EP400	physical	11509179
ATX7_HUMAN	ATXN7	physical	16494529
KAT2A_HUMAN	KAT2A	physical	16494529
P53_HUMAN	TP53	physical	12138177
MED1_HUMAN	MED1	physical	18418385
MED23_HUMAN	MED23	physical	18418385
KAT2A_HUMAN	KAT2A	physical	18418385
MED26_HUMAN	MED26	physical	18418385
CDK8_HUMAN	CDK8	physical	18418385
MED12_HUMAN	MED12	physical	18418385
MED13_HUMAN	MED13	physical	18418385
MED14_HUMAN	MED14	physical	18418385
MED15_HUMAN	MED15	physical	18418385
MED16_HUMAN	MED16	physical	18418385
MED17_HUMAN	MED17	physical	18418385
MED24_HUMAN	MED24	physical	18418385
MED25_HUMAN	MED25	physical	18418385
MYC_HUMAN	MYC	physical	11511539
NPAT_HUMAN	NPAT	physical	17967892
KAT2A_HUMAN	KAT2A	physical	20508642
SGF29_HUMAN	CCDC101	physical	20508642
UL27_HCMVM	UL27	physical	21320693
NPAT_HUMAN	NPAT	physical	22288532
SRBP2_HUMAN	SREBF2	physical	22288532
CDN1A_HUMAN	CDKN1A	physical	12897156
SKP1_HUMAN	SKP1	physical	19066453
CUL1_HUMAN	CUL1	physical	19066453
MRE11_HUMAN	MRE11A	physical	23318449
CDC20_HUMAN	CDC20	physical	23318449
TAF5_HUMAN	TAF5	physical	15870280
TAF6_HUMAN	TAF6	physical	15870280
UBP7_HUMAN	USP7	physical	25925205
BTAF1_HUMAN	BTAF1	physical	26344197
VPS72_HUMAN	VPS72	physical	26496610
YETS4_HUMAN	YEATS4	physical	26496610
SUPT3_HUMAN	SUPT3H	physical	26496610
RUVB1_HUMAN	RUVBL1	physical	26496610
TTI1_HUMAN	TTI1	physical	26496610
ST65G_HUMAN	SUPT7L	physical	26496610
TADA3_HUMAN	TADA3	physical	26496610
RUVB2_HUMAN	RUVBL2	physical	26496610
BRD8_HUMAN	BRD8	physical	26496610
EPC2_HUMAN	EPC2	physical	26496610
ING3_HUMAN	ING3	physical	26496610
SP20H_HUMAN	SUPT20H	physical	26496610
DMAP1_HUMAN	DMAP1	physical	26496610
EP400_HUMAN	EP400	physical	26496610
TTI2_HUMAN	TTI2	physical	26496610
EPC1_HUMAN	EPC1	physical	26496610
TAD2B_HUMAN	TADA2B	physical	26496610
SGF29_HUMAN	CCDC101	physical	26496610
TADA1_HUMAN	TADA1	physical	26496610
K2C72_HUMAN	KRT72	physical	26496610
JAZF1_HUMAN	JAZF1	physical	26496610
BRNP1_HUMAN	BRINP1	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TRRAP_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-2543 AND LYS-3078, AND MASSSPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2051, AND MASSSPECTROMETRY.	19690332 [Abstract]
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1628, AND MASSSPECTROMETRY.	19369195 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2051 AND SER-2077, ANDMASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1628; SER-2051;SER-2077; THR-2333 AND THR-2601, AND MASS SPECTROMETRY.	18691976 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2051, AND MASSSPECTROMETRY.	15302935 [Abstract]