| UniProt ID | UL27_HCMVM | |
|---|---|---|
| UniProt AC | Q6SWA4 | |
| Protein Name | Protein UL27 | |
| Gene Name | UL27 | |
| Organism | Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5). | |
| Sequence Length | 608 | |
| Subcellular Localization | Host nucleus . Host nucleus, host nucleolus . | |
| Protein Description | Promotes a cell cycle arrest in G0/G1 by inducing the proteasomal degradation of host histone acetyltransferase KAT5/Tip60.. | |
| Protein Sequence | MNPVDQPPPPPLTQQPEEQAKEDHDDGDERLFRDPLTTYEYLDDCRDDEEFCHQFLRAYLTPIRNRQEAVRAGLLCRTPEDLAAAGGQKRKTPAPKHPKHAMVYIRRSCLVHSACATAHGKYDIRGLTLESDLAVWAALRGVPLPPDPQHFRWLNAGAFRRLVHEAQYLPEISRAAKRIALAVATGQYVVCTLLDYKTFGTRTHYLRQLCSMTEELYLRLDGTLCLFLEPEERELIGRCLPAALCRGLPVKYRTHRAAVFFHATFMARAEAALKDLYAAFCECGDGRDDGGNHNGNYGGGDHSSLSPSAVASHHSRLEHAELRLERNRHLGAFHLPAIRHLTAGDVARVQDSVSRDLGFADWSQTLVDDYFLLPAGWACANPRRGYAMYLASNAVLALRIIRLLRASIRHEYTACIRMLSGDVQRLIRLFKGEAALLRKGLAQNPVQRRELSRFRKHVHDLKRIRFTEDTFVETFCDFLELVQRIPDYRSVSLRIKRELLCLHVFKLRRGCRAPPTPEAVRVQRLLWHSLRHGDAPQDRTRLPQFSSALSDAELSNHANRCRRKAPLELGPAVVAAPGPSVRYRAHIQKFERLHVRRFRPHEVGGHAT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of UL27_HCMVM !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of UL27_HCMVM !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UL27_HCMVM !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UL27_HCMVM !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TRRAP_HUMAN | TRRAP | physical | 21320693 | |
| PSME3_HUMAN | PSME3 | physical | 21320693 | |
| UBR5_HUMAN | UBR5 | physical | 21320693 | |
| EP400_HUMAN | EP400 | physical | 21320693 | |
| ACLY_HUMAN | ACLY | physical | 21320693 | |
| RUVB2_HUMAN | RUVBL2 | physical | 21320693 | |
| RAN_HUMAN | RAN | physical | 21320693 | |
| HNRH3_HUMAN | HNRNPH3 | physical | 21320693 | |
| CBR1_HUMAN | CBR1 | physical | 21320693 | |
| PRS6B_HUMAN | PSMC4 | physical | 21320693 | |
| FKB10_HUMAN | FKBP10 | physical | 21320693 | |
| PSA3_HUMAN | PSMA3 | physical | 21320693 | |
| RUVB1_HUMAN | RUVBL1 | physical | 21320693 | |
| CPSF5_HUMAN | NUDT21 | physical | 21320693 | |
| TMM43_HUMAN | TMEM43 | physical | 21320693 | |
| RAB1A_HUMAN | RAB1A | physical | 21320693 | |
| PDIA4_HUMAN | PDIA4 | physical | 21320693 | |
| PSB6_HUMAN | PSMB6 | physical | 21320693 | |
| ACL6A_HUMAN | ACTL6A | physical | 21320693 | |
| DDB1_HUMAN | DDB1 | physical | 21320693 | |
| WDR26_HUMAN | WDR26 | physical | 21320693 | |
| PSB4_HUMAN | PSMB4 | physical | 21320693 | |
| PSMD2_HUMAN | PSMD2 | physical | 21320693 | |
| PRS10_HUMAN | PSMC6 | physical | 21320693 | |
| PSMD3_HUMAN | PSMD3 | physical | 21320693 | |
| STAT3_HUMAN | STAT3 | physical | 21320693 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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