TADA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TADA1_HUMAN
• UniProt AC: Q96BN2
• Protein Name: Transcriptional adapter 1
• Gene Name: TADA1
• Organism: Homo sapiens (Human).
• Sequence Length: 335
• Subcellular Localization: Nucleus .
• Protein Description: Probably involved in transcriptional regulation..
• Protein Sequence: MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Ubiquitination	VSELEAAKKNLSEAL HHHHHHHHHHHHHHH	49.60	-
13	Ubiquitination	SELEAAKKNLSEALG HHHHHHHHHHHHHHC	59.39	29967540
24	Ubiquitination	EALGDNVKQYWANLK HHHCHHHHHHHHHHH	43.88	29967540
35	Ubiquitination	ANLKLWFKQKISKEE HHHHHHHHHCCCHHH	38.82	-
40	Ubiquitination	WFKQKISKEEFDLEA HHHHCCCHHHHCHHH	65.81	29967540
75	Phosphorylation	TRCQILVSTPDGAGS HHCEEEEECCCCCCC	30.67	27251275
76	Phosphorylation	RCQILVSTPDGAGSL HCEEEEECCCCCCCC	20.23	21712546
82	Phosphorylation	STPDGAGSLPWPGGS ECCCCCCCCCCCCCC	30.63	27251275
89	Phosphorylation	SLPWPGGSAAKPGKP CCCCCCCCCCCCCCC	30.85	21712546
103	Phosphorylation	PKGKKKLSSVRQKFD CCCCCHHHHHHHHCC	35.35	24719451
120	Phosphorylation	FQPQNPLSGAQQFVA CCCCCCCCHHHHHHH	33.08	28176443
128	Ubiquitination	GAQQFVAKDPQDDDD HHHHHHHCCCCCCCC	65.72	29967540
205	Ubiquitination	RLRDGHFKYAFGSNV HCCCCCCCCCCCCCC	29.96	-
213	Phosphorylation	YAFGSNVTPQPYLKN CCCCCCCCCCCCCCC	22.06	25159151
320	Ubiquitination	HEELQQDKVHRQRLA HHHHHHHHHHHHHHH	35.29	29967540
329	Ubiquitination	HRQRLAAKEGLLLC- HHHHHHHHHCCCCC-	46.86	22505724

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TADA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TADA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TADA1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TAF6L_HUMAN	TAF6L	physical	26186194
TRRAP_HUMAN	TRRAP	physical	26186194
TAF9B_HUMAN	TAF9B	physical	26186194
TAF9_HUMAN	TAF9	physical	26186194
TAF10_HUMAN	TAF10	physical	26186194
CCHL_HUMAN	HCCS	physical	26186194
TAF5L_HUMAN	TAF5L	physical	26186194
TAF12_HUMAN	TAF12	physical	26186194
ST65G_HUMAN	SUPT7L	physical	26186194
KAT2B_HUMAN	KAT2B	physical	26186194
SP20H_HUMAN	SUPT20H	physical	26186194
TAD2B_HUMAN	TADA2B	physical	26186194
SF3B5_HUMAN	SF3B5	physical	26186194
TAD2B_HUMAN	TADA2B	physical	28514442
TAF6L_HUMAN	TAF6L	physical	28514442
TAF5L_HUMAN	TAF5L	physical	28514442
ST65G_HUMAN	SUPT7L	physical	28514442
TAF9B_HUMAN	TAF9B	physical	28514442
TAF12_HUMAN	TAF12	physical	28514442
SP20H_HUMAN	SUPT20H	physical	28514442
TAF9_HUMAN	TAF9	physical	28514442
TAF10_HUMAN	TAF10	physical	28514442
KAT2B_HUMAN	KAT2B	physical	28514442
TRRAP_HUMAN	TRRAP	physical	28514442
CCHL_HUMAN	HCCS	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.