| UniProt ID | TAD2B_HUMAN | |
|---|---|---|
| UniProt AC | Q86TJ2 | |
| Protein Name | Transcriptional adapter 2-beta | |
| Gene Name | TADA2B | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 420 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2.. | |
| Protein Sequence | MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 17 | Phosphorylation | VYCLAEVSPLRFRCT HHHHHCCCCCEEECC | 15.10 | 23898821 | |
| 133 | Phosphorylation | DTIPNRVTDHTCPSG CCCCCCCCCCCCCCC | 20.87 | 25850435 | |
| 136 | Phosphorylation | PNRVTDHTCPSGGPL CCCCCCCCCCCCCCC | 28.99 | 25850435 | |
| 139 | Phosphorylation | VTDHTCPSGGPLSPS CCCCCCCCCCCCCCC | 59.53 | 25850435 | |
| 144 | Phosphorylation | CPSGGPLSPSLTTPL CCCCCCCCCCCCCCC | 18.64 | 25850435 | |
| 146 | Phosphorylation | SGGPLSPSLTTPLPP CCCCCCCCCCCCCCC | 34.67 | 26074081 | |
| 148 | Phosphorylation | GPLSPSLTTPLPPLD CCCCCCCCCCCCCCC | 30.61 | 26074081 | |
| 149 | Phosphorylation | PLSPSLTTPLPPLDI CCCCCCCCCCCCCCC | 28.28 | 25850435 | |
| 157 | Phosphorylation | PLPPLDISVAEQQQL CCCCCCCCHHHHHCC | 18.23 | 25850435 | |
| 209 | Phosphorylation | KRAHVDMYVRKLKER HHHHHHHHHHHHHHH | 7.82 | 28270605 | |
| 227 | Ubiquitination | KNIARDYNLVPAFLG HHHHHHHCHHHHHCC | 38.56 | 22505724 | |
| 236 | Ubiquitination | VPAFLGKDKKEKEKA HHHHCCCCHHHHHHH | 66.51 | 22505724 | |
| 280 | Ubiquitination | DLFENMHKEKMLRAK HHHHHHHHHHHHHHH | 48.54 | 29967540 | |
| 319 | Ubiquitination | RHKREKRKENKNLAG HHHHHHHHHHCCCCC | 76.37 | 22505724 | |
| 328 | Ubiquitination | NKNLAGSKRGKEDGK HCCCCCCCCCCCCCC | 65.34 | 22505724 | |
| 361 | Phosphorylation | REKVLCSSLNLSPAR HHHHHHHHCCCCCCC | 21.93 | - | |
| 365 | Phosphorylation | LCSSLNLSPARYVTV HHHHCCCCCCCEEEE | 18.55 | 28450419 | |
| 369 | Phosphorylation | LNLSPARYVTVKTII CCCCCCCEEEEEEEE | 11.54 | 21214269 | |
| 389 | Phosphorylation | QKRQGIPSKSRLPSY HHHCCCCCHHHCCHH | 41.15 | 24719451 | |
| 410 | Phosphorylation | KRILNFLTESGWISR HHHHHHHHHHCCCCC | 24.78 | 28111955 | |
| 412 | Phosphorylation | ILNFLTESGWISRDA HHHHHHHHCCCCCCC | 33.90 | 28111955 | |
| 416 | Phosphorylation | LTESGWISRDAS--- HHHHCCCCCCCC--- | 20.00 | 28111955 | |
| 420 | Phosphorylation | GWISRDAS------- CCCCCCCC------- | 45.07 | 28111955 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TAD2B_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TAD2B_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TAD2B_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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