| UniProt ID | SUPT3_HUMAN | |
|---|---|---|
| UniProt AC | O75486 | |
| Protein Name | Transcription initiation protein SPT3 homolog | |
| Gene Name | SUPT3H | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 317 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Probable transcriptional activator.. | |
| Protein Sequence | MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVVHTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGIDEDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTRIMDSAQYAEFCESRQLSFSKKASKFRDWLDCSSMEIKPNVVAMEILAYLAYETVAQLVDLALLVRQDMVTKAGDPFSHAISATFIQYHNSAESTAACGVEAHSDAIQPCHIREAIRRYSHRIGPLSPFTNAYRRNGMAFLAC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MNNTAASP -------CCCCCCCC | 7.25 | 22814378 | |
| 7 | Phosphorylation | -MNNTAASPMSTATS -CCCCCCCCCCCCCC | 30.64 | 24719451 | |
| 7 (in isoform 2) | Phosphorylation | - | 30.64 | 25849741 | |
| 10 (in isoform 2) | Phosphorylation | - | 31.49 | 22210691 | |
| 12 | Phosphorylation | AASPMSTATSSSGRS CCCCCCCCCCCCCCC | 21.69 | 28787133 | |
| 16 | Phosphorylation | MSTATSSSGRSTGKS CCCCCCCCCCCCCCC | 20.20 | 28787133 | |
| 19 (in isoform 2) | Phosphorylation | - | 25.04 | 22210691 | |
| 19 | Phosphorylation | ATSSSGRSTGKSISF CCCCCCCCCCCCCCH | 25.04 | 28787133 | |
| 20 (in isoform 2) | Phosphorylation | - | 51.14 | 22210691 | |
| 21 | Phosphorylation | SSSGRSTGKSISFAT CCCCCCCCCCCCHHH | 43.03 | 28787133 | |
| 42 | Phosphorylation | YSLGDARRPLHETAV HHCCCCCCCHHHHHH | 36.19 | 26329039 | |
| 86 | Phosphorylation | TPEDLLFLMRKDKKK CHHHHHHHHHCCHHH | 20.70 | 27732954 | |
| 89 | Phosphorylation | DLLFLMRKDKKKLRR HHHHHHHCCHHHHHH | 20.76 | 19664995 | |
| 92 | Phosphorylation | FLMRKDKKKLRRLLK HHHHCCHHHHHHHHH | 20.48 | 20860994 | |
| 93 | Phosphorylation | LMRKDKKKLRRLLKY HHHCCHHHHHHHHHH | 27.92 | 27251275 | |
| 95 | Phosphorylation | RKDKKKLRRLLKYMF HCCHHHHHHHHHHHH | 29.27 | 27732954 | |
| 96 | Phosphorylation | KDKKKLRRLLKYMFI CCHHHHHHHHHHHHH | 21.75 | 27251275 | |
| 98 | Phosphorylation | KKKLRRLLKYMFIRD HHHHHHHHHHHHHHH | 37.68 | - | |
| 112 | Sumoylation | DYKSKIVKGIDEDDL HHHHHHCCCCCHHHH | 3.87 | 28112733 | |
| 112 | Ubiquitination | DYKSKIVKGIDEDDL HHHHHHCCCCCHHHH | 3.87 | - | |
| 123 | Ubiquitination | EDDLLEDKLSGSNNA HHHHHHHHHCCCCCH | 45.55 | - | |
| 123 | Sumoylation | EDDLLEDKLSGSNNA HHHHHHHHHCCCCCH | 45.55 | 28112733 | |
| 163 | Sumoylation | DDEIDEVKQERMERA CCCHHHHHHHHHHHH | 53.28 | 28112733 | |
| 205 | Ubiquitination | SKFRDWLDCSSMEIK HHHCHHHCCCCCCCC | 34.87 | - | |
| 205 | Sumoylation | SKFRDWLDCSSMEIK HHHCHHHCCCCCCCC | 34.87 | - | |
| 261 | Phosphorylation | AISATFIQYHNSAES HHHHHHHHHCCCCCC | 10.41 | - | |
| 264 | Phosphorylation | ATFIQYHNSAESTAA HHHHHHCCCCCCHHC | 14.07 | - | |
| 270 | Phosphorylation | HNSAESTAACGVEAH CCCCCCHHCCCCCCC | 26.89 | - | |
| 274 | Phosphorylation | ESTAACGVEAHSDAI CCHHCCCCCCCCCCC | 21.09 | 24719451 | |
| 301 | Phosphorylation | SHRIGPLSPFTNAYR HHHHCCCCHHCCHHH | 25.72 | - | |
| 334 | Phosphorylation | ------------------------ ------------------------ | 19.87 | - | |
| 338 | Phosphorylation | ---------------------------- ---------------------------- | 23.26 | 22210691 | |
| 383 | Phosphorylation | ------------------------------------------------------------------------- ------------------------------------------------------------------------- | 22.54 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SUPT3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SUPT3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SUPT3_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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