ZN182_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN182_HUMAN
• UniProt AC: P17025
• Protein Name: Zinc finger protein 182
• Gene Name: ZNF182
• Organism: Homo sapiens (Human).
• Sequence Length: 639
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MTPASASGEDSGSFYSWQKAKREQGLVTFEDVAVDFTQEEWQYLNPPQRTLYRDVMLETYSNLVFVGQQVTKPNLILKLEVEECPAEGKIPFWNFPEVCQVDEQIERQHQDDQDKCLLMQVGFSDKKTIITKSARDCHEFGNILHLSTNLVASIQRPDKHESFGNNMVDNLDLFSRSSAENKYDNGCAKLFFHTEYEKTNPGMKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKPFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPYECNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNECKKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVHQRTHAGKKAHGRGHTRKSKFMAH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	ASGEDSGSFYSWQKA CCCCCCCCCCCCHHC	25.59	22210691
70	Ubiquitination	LVFVGQQVTKPNLIL EEEEECCCCCCCEEE	5.97	29967540
89	Ubiquitination	EECPAEGKIPFWNFP EECCCCCCCCCCCCH	38.42	29967540
124	Phosphorylation	LLMQVGFSDKKTIIT EEEEECCCCCCEEEE	42.46	29507054
128	Phosphorylation	VGFSDKKTIITKSAR ECCCCCCEEEECCHH	24.29	-
131	Phosphorylation	SDKKTIITKSARDCH CCCCEEEECCHHHHH	18.33	-
133	Phosphorylation	KKTIITKSARDCHEF CCEEEECCHHHHHHH	21.64	-
153	Phosphorylation	LSTNLVASIQRPDKH HHCCHHHHCCCCCCC	16.27	24719451
200	Ubiquitination	HTEYEKTNPGMKPYG ECEEHHCCCCCCCCC	42.04	29967540
219	Ubiquitination	GKGLRRKKGLSLHQR CCCHHHCCCCCHHHH	64.37	29967540
222	Phosphorylation	LRRKKGLSLHQRIKN HHHCCCCCHHHHHHC	32.26	-
228	Acetylation	LSLHQRIKNGEKPFE CCHHHHHHCCCCCEE	62.17	20167786
232	Acetylation	QRIKNGEKPFECTAC HHHHCCCCCEECEEE	57.30	20167786
241	Acetylation	FECTACRKTFSKKSH EECEEEECCCCCCCE	54.53	20167786
255	Phosphorylation	HLIVHWRTHTGEKPF EEEEEEECCCCCCCC	20.71	-
257	Phosphorylation	IVHWRTHTGEKPFGC EEEEECCCCCCCCCC	46.56	-
285	Phosphorylation	IIHLRTHTGERPFEC EEEEEECCCCCCCCC	39.87	19664995
303	Phosphorylation	GKAFREKSTVIIHYR CHHHHHCCEEEEEEE	24.13	19664995
304	Phosphorylation	KAFREKSTVIIHYRT HHHHHCCEEEEEEEE	27.13	19664995
309	Phosphorylation	KSTVIIHYRTHTGEK CCEEEEEEEECCCCC	13.54	19664995
311	Ubiquitination	TVIIHYRTHTGEKPY EEEEEEEECCCCCCE	19.34	29967540
311	Phosphorylation	TVIIHYRTHTGEKPY EEEEEEEECCCCCCE	19.34	28348404
313	Phosphorylation	IIHYRTHTGEKPYEC EEEEEECCCCCCEEC	46.56	29496963
316	Ubiquitination	YRTHTGEKPYECNEC EEECCCCCCEECCCC	55.00	-
319	Ubiquitination	HTGEKPYECNECGKA CCCCCCEECCCCCCC	39.12	29967540
330	Ubiquitination	CGKAFTQKSNLIVHQ CCCCCCCCCCEEEEE	37.95	29967540
338	Ubiquitination	SNLIVHQKTHTGEKT CCEEEEECCCCCCCE	27.65	29967540
339	Phosphorylation	NLIVHQKTHTGEKTY CEEEEECCCCCCCEE	20.35	29978859
341	Phosphorylation	IVHQKTHTGEKTYEC EEEECCCCCCCEEEE	52.87	29978859
366	Phosphorylation	LDLIIHHSTHTGKKP HCEEEECCCCCCCCC	14.02	-
388	Phosphorylation	KTFSDKSTLIIHQRT CCCCCCCEEEEEEEC	27.93	-
395	Phosphorylation	TLIIHQRTHTGEKPH EEEEEEECCCCCCCC	19.74	-
397	Phosphorylation	IIHQRTHTGEKPHKC EEEEECCCCCCCCCC	46.56	-
423	Phosphorylation	TLIVHQRTHTGEKPY EEEEEECCCCCCCCE	19.74	-
423	Ubiquitination	TLIVHQRTHTGEKPY EEEEEECCCCCCCCE	19.74	29967540
425	Phosphorylation	IVHQRTHTGEKPYEC EEEECCCCCCCCEEE	46.56	28555341
442	Ubiquitination	CGKTFTQKSNLGVHQ CCCEEECCCCCCCCC	37.95	29967540
443	Phosphorylation	GKTFTQKSNLGVHQR CCEEECCCCCCCCCC	27.72	30576142
453	Phosphorylation	GVHQRTHSGEKPFEC CCCCCCCCCCCCCCC	48.29	30576142
472	Phosphorylation	KAFSQKSYLMLHQRG HHHHCCCEEEECCCC	11.81	-
499	Phosphorylation	EKAFSQKSYLIIHQR HHHHCCCCEEEEECC	19.96	30622161
500	Phosphorylation	KAFSQKSYLIIHQRT HHHCCCCEEEEECCC	14.68	30622161
507	Phosphorylation	YLIIHQRTHTEEKPY EEEEECCCCCCCCCC	26.95	30622161
509	Phosphorylation	IIHQRTHTEEKPYKC EEECCCCCCCCCCCC	45.27	30622161
515	Sumoylation	HTEEKPYKCNECGKA CCCCCCCCCCCCHHH	38.83	-
515	Sumoylation	HTEEKPYKCNECGKA CCCCCCCCCCCCHHH	38.83	-
537	Phosphorylation	IIHQRIHTGEKPYEC EEEEEEECCCCCCCC	44.67	28111955
554	Sumoylation	CWKAFSQKSQLIIHQ CHHHHCCCCEEEEEE	38.68	-
554	Sumoylation	CWKAFSQKSQLIIHQ CHHHHCCCCEEEEEE	38.68	-
563	Phosphorylation	QLIIHQRTHTGEKPY EEEEEECCCCCCCCE	19.74	-
565	Phosphorylation	IIHQRTHTGEKPYAC EEEECCCCCCCCEEE	46.56	-
570	Phosphorylation	THTGEKPYACTECGK CCCCCCCEEECHHHH	25.94	-
577	Ubiquitination	YACTECGKAFREKST EEECHHHHHHHHCCC	56.88	-
591	Phosphorylation	TFTVHQRTHTGEKPY CEEEEECCCCCCCCE	19.74	28348404
593	Phosphorylation	TVHQRTHTGEKPYKC EEEECCCCCCCCEEE	46.56	26270265
596	Ubiquitination	QRTHTGEKPYKCTEC ECCCCCCCCEEECCC	55.80	-
610	Ubiquitination	CGKAFTQKSNLIVHQ CCCCCCCCCCEEEEE	37.95	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN182_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN182_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN182_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN182_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.