BCLF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BCLF1_HUMAN
• UniProt AC: Q9NYF8
• Protein Name: Bcl-2-associated transcription factor 1
• Gene Name: BCLAF1
• Organism: Homo sapiens (Human).
• Sequence Length: 920
• Subcellular Localization: Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm .
• Protein Description: Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA..
• Protein Sequence: MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MGRSNSRSHSSRS --CCCCCCCCCCCCC	36.08	-
10	Phosphorylation	RSNSRSHSSRSKSRS CCCCCCCCCCCCCCC	28.79	24505115
11	Ubiquitination	SNSRSHSSRSKSRSQ CCCCCCCCCCCCCCC	34.84	21890473
15	Phosphorylation	SHSSRSKSRSQSSSR CCCCCCCCCCCCCHH	38.11	24505115
19	Phosphorylation	RSKSRSQSSSRSRSR CCCCCCCCCHHHHHH	31.37	24260401
20	Phosphorylation	SKSRSQSSSRSRSRS CCCCCCCCHHHHHHH	23.33	24260401
29	Phosphorylation	RSRSRSHSRKKRYSS HHHHHHHHHHHHHHH	47.22	28634120
34	Phosphorylation	SHSRKKRYSSRSRSR HHHHHHHHHHHHHCC	21.63	21406692
35	Phosphorylation	HSRKKRYSSRSRSRT HHHHHHHHHHHHCCC	24.25	21406692
36	Phosphorylation	SRKKRYSSRSRSRTY HHHHHHHHHHHCCCC	25.91	21406692
38	Phosphorylation	KKRYSSRSRSRTYSR HHHHHHHHHCCCCCC	36.23	21406692
40	Phosphorylation	RYSSRSRSRTYSRSR HHHHHHHCCCCCCHH	30.16	24144214
42	Phosphorylation	SSRSRSRTYSRSRSR HHHHHCCCCCCHHHC	27.39	24144214
43	Phosphorylation	SRSRSRTYSRSRSRD HHHHCCCCCCHHHCC	10.85	24144214
44	Phosphorylation	RSRSRTYSRSRSRDR HHHCCCCCCHHHCCC	24.14	21406692
46	Phosphorylation	RSRTYSRSRSRDRMY HCCCCCCHHHCCCCC	28.77	20068231
48	Phosphorylation	RTYSRSRSRDRMYSR CCCCCHHHCCCCCCH	39.52	20068231
54	Phosphorylation	RSRDRMYSRDYRRDY HHCCCCCCHHHHHHH	14.88	27251275
55	Methylation	SRDRMYSRDYRRDYR HCCCCCCHHHHHHHH	27.73	-
65	Ubiquitination	RRDYRNNRGMRRPYG HHHHHCCCCCCCCCC	43.78	24816145
76	Dimethylation	RPYGYRGRGRGYYQG CCCCCCCCCCCCCCC	23.72	-
76	Methylation	RPYGYRGRGRGYYQG CCCCCCCCCCCCCCC	23.72	-
78	Dimethylation	YGYRGRGRGYYQGGG CCCCCCCCCCCCCCC	28.69	-
78	Methylation	YGYRGRGRGYYQGGG CCCCCCCCCCCCCCC	28.69	-
80	Phosphorylation	YRGRGRGYYQGGGGR CCCCCCCCCCCCCCC	7.40	22817900
81	Phosphorylation	RGRGRGYYQGGGGRY CCCCCCCCCCCCCCC	11.96	22817900
87	Dimethylation	YYQGGGGRYHRGGYR CCCCCCCCCCCCCCC	27.62	-
87	Methylation	YYQGGGGRYHRGGYR CCCCCCCCCCCCCCC	27.62	-
88	Phosphorylation	YQGGGGRYHRGGYRP CCCCCCCCCCCCCCC	10.11	-
90	Dimethylation	GGGGRYHRGGYRPVW CCCCCCCCCCCCCCC	31.15	-
90	Methylation	GGGGRYHRGGYRPVW CCCCCCCCCCCCCCC	31.15	-
93	Phosphorylation	GRYHRGGYRPVWNRR CCCCCCCCCCCCCCC	17.99	22817900
94	Methylation	RYHRGGYRPVWNRRH CCCCCCCCCCCCCCC	23.67	-
102	Phosphorylation	PVWNRRHSRSPRRGR CCCCCCCCCCCCCCC	32.42	27362937
104	Phosphorylation	WNRRHSRSPRRGRSR CCCCCCCCCCCCCCC	26.27	27362937
114	Phosphorylation	RGRSRSRSPKRRSVS CCCCCCCCCCHHCHH	35.70	29743597
119	Phosphorylation	SRSPKRRSVSSQRSR CCCCCHHCHHHHHHH	30.31	28176443
121	Phosphorylation	SPKRRSVSSQRSRSR CCCHHCHHHHHHHHH	23.23	28176443
122	Phosphorylation	PKRRSVSSQRSRSRS CCHHCHHHHHHHHHH	27.70	28176443
125	Phosphorylation	RSVSSQRSRSRSRRS HCHHHHHHHHHHHHH	27.28	20363803
127	Phosphorylation	VSSQRSRSRSRRSYR HHHHHHHHHHHHHHH	35.54	28102081
129	Phosphorylation	SQRSRSRSRRSYRSS HHHHHHHHHHHHHHC	33.04	29449344
132	Phosphorylation	SRSRSRRSYRSSRSP HHHHHHHHHHHCCCC	24.64	20363803
133	Phosphorylation	RSRSRRSYRSSRSPR HHHHHHHHHHCCCCC	16.83	21406692
135	Phosphorylation	RSRRSYRSSRSPRSS HHHHHHHHCCCCCCC	23.13	20363803
136	Phosphorylation	SRRSYRSSRSPRSSS HHHHHHHCCCCCCCC	27.98	20363803
138	Phosphorylation	RSYRSSRSPRSSSSR HHHHHCCCCCCCCCC	26.98	21406692
141	Phosphorylation	RSSRSPRSSSSRSSS HHCCCCCCCCCCCCC	37.65	20044836
142	Phosphorylation	SSRSPRSSSSRSSSP HCCCCCCCCCCCCCC	33.34	29438985
143	Phosphorylation	SRSPRSSSSRSSSPY CCCCCCCCCCCCCCC	30.90	29438985
146	Phosphorylation	PRSSSSRSSSPYSKS CCCCCCCCCCCCCCC	36.80	23927012
147	Phosphorylation	RSSSSRSSSPYSKSP CCCCCCCCCCCCCCC	33.93	23927012
148	Phosphorylation	SSSSRSSSPYSKSPV CCCCCCCCCCCCCCC	29.15	23927012
150	Acetylation	SSRSSSPYSKSPVSK CCCCCCCCCCCCCCC	30.58	19608861
150	Phosphorylation	SSRSSSPYSKSPVSK CCCCCCCCCCCCCCC	30.58	23927012
151	Phosphorylation	SRSSSPYSKSPVSKR CCCCCCCCCCCCCCC	30.00	23927012
152	Acetylation	RSSSPYSKSPVSKRR CCCCCCCCCCCCCCC	53.59	19608861
153	Phosphorylation	SSSPYSKSPVSKRRG CCCCCCCCCCCCCCC	25.29	23401153
156	Phosphorylation	PYSKSPVSKRRGSQE CCCCCCCCCCCCCHH	24.67	20044836
161	Phosphorylation	PVSKRRGSQEKQTKK CCCCCCCCHHHHHHH	33.10	27422710
166	Phosphorylation	RGSQEKQTKKAEGEP CCCHHHHHHHCCCCC	45.65	26074081
168	Sumoylation	SQEKQTKKAEGEPQE CHHHHHHHCCCCCCC	55.87	-
168	Sumoylation	SQEKQTKKAEGEPQE CHHHHHHHCCCCCCC	55.87	-
175	Phosphorylation	KAEGEPQEESPLKSK HCCCCCCCCCCCCCC	71.77	32142685
177	Phosphorylation	EGEPQEESPLKSKSQ CCCCCCCCCCCCCCC	34.48	22167270
178	Neddylation	GEPQEESPLKSKSQE CCCCCCCCCCCCCCC	47.27	32015554
178	Ubiquitination	GEPQEESPLKSKSQE CCCCCCCCCCCCCCC	47.27	32015554
180	Neddylation	PQEESPLKSKSQEEP CCCCCCCCCCCCCCC	60.26	32015554
180	Ubiquitination	PQEESPLKSKSQEEP CCCCCCCCCCCCCCC	60.26	32015554
181	Phosphorylation	QEESPLKSKSQEEPK CCCCCCCCCCCCCCC	45.26	20201521
183	Phosphorylation	ESPLKSKSQEEPKDT CCCCCCCCCCCCCCC	50.33	29255136
186	Ubiquitination	LKSKSQEEPKDTFEH CCCCCCCCCCCCCCC	50.44	29967540
188	Acetylation	SKSQEEPKDTFEHDP CCCCCCCCCCCCCCC	73.08	26051181
188	Sumoylation	SKSQEEPKDTFEHDP CCCCCCCCCCCCCCC	73.08	28112733
188	Ubiquitination	SKSQEEPKDTFEHDP CCCCCCCCCCCCCCC	73.08	29967540
190	Phosphorylation	SQEEPKDTFEHDPSE CCCCCCCCCCCCCCC	36.73	30266825
196	Phosphorylation	DTFEHDPSESIDEFN CCCCCCCCCCHHHHH	50.46	29255136
198	Phosphorylation	FEHDPSESIDEFNKS CCCCCCCCHHHHHHH	39.41	29255136
205	Phosphorylation	SIDEFNKSSATSGDI CHHHHHHHCCCCCCC	26.72	26503892
206	Phosphorylation	IDEFNKSSATSGDIW HHHHHHHCCCCCCCC	36.86	23927012
208	Phosphorylation	EFNKSSATSGDIWPG HHHHHCCCCCCCCCC	34.88	20201521
209	Phosphorylation	FNKSSATSGDIWPGL HHHHCCCCCCCCCCC	33.90	25159151
217	Phosphorylation	GDIWPGLSAYDNSPR CCCCCCCCCCCCCCC	30.60	30266825
219	Phosphorylation	IWPGLSAYDNSPRSP CCCCCCCCCCCCCCC	16.57	23927012
220	Phosphorylation	WPGLSAYDNSPRSPH CCCCCCCCCCCCCCC	49.17	32142685
222	Phosphorylation	GLSAYDNSPRSPHSP CCCCCCCCCCCCCCC	20.84	19664994
225	Phosphorylation	AYDNSPRSPHSPSPI CCCCCCCCCCCCCCC	30.28	25159151
228	Phosphorylation	NSPRSPHSPSPIATP CCCCCCCCCCCCCCC	30.38	23401153
230	Phosphorylation	PRSPHSPSPIATPPS CCCCCCCCCCCCCCC	31.77	23927012
231	Ubiquitination	RSPHSPSPIATPPSQ CCCCCCCCCCCCCCC	24.50	22817900
232	Phosphorylation	SPHSPSPIATPPSQS CCCCCCCCCCCCCCC	8.60	33259812
233	Ubiquitination	PHSPSPIATPPSQSS CCCCCCCCCCCCCCC	19.89	22817900
234	Phosphorylation	HSPSPIATPPSQSSS CCCCCCCCCCCCCCC	36.13	23927012
234	Ubiquitination	HSPSPIATPPSQSSS CCCCCCCCCCCCCCC	36.13	21890473
237	Phosphorylation	SPIATPPSQSSSCSD CCCCCCCCCCCCCCC	43.85	23927012
239	Phosphorylation	IATPPSQSSSCSDAP CCCCCCCCCCCCCCC	28.67	23927012
240	Phosphorylation	ATPPSQSSSCSDAPM CCCCCCCCCCCCCCC	27.94	23927012
241	Phosphorylation	TPPSQSSSCSDAPML CCCCCCCCCCCCCCH	23.92	23927012
243	Phosphorylation	PSQSSSCSDAPMLST CCCCCCCCCCCCHHH	38.46	23927012
249	Phosphorylation	CSDAPMLSTVHSAKN CCCCCCHHHHHCCCC	23.33	23663014
250	Phosphorylation	SDAPMLSTVHSAKNT CCCCCHHHHHCCCCC	20.48	23663014
253	Phosphorylation	PMLSTVHSAKNTPSQ CCHHHHHCCCCCCCC	36.28	23663014
257	Phosphorylation	TVHSAKNTPSQHSHS HHHCCCCCCCCCCCC	24.50	29255136
259	Phosphorylation	HSAKNTPSQHSHSIQ HCCCCCCCCCCCCCC	38.19	29255136
262	Phosphorylation	KNTPSQHSHSIQHSP CCCCCCCCCCCCCCC	15.99	29255136
264	Phosphorylation	TPSQHSHSIQHSPER CCCCCCCCCCCCCCC	27.27	29255136
268	Phosphorylation	HSHSIQHSPERSGSG CCCCCCCCCCCCCCC	16.45	29255136
272	Phosphorylation	IQHSPERSGSGSVGN CCCCCCCCCCCCCCC	35.33	26503892
274	Phosphorylation	HSPERSGSGSVGNGS CCCCCCCCCCCCCCC	29.19	23927012
276	Phosphorylation	PERSGSGSVGNGSSR CCCCCCCCCCCCCCC	28.66	23927012
281	Phosphorylation	SGSVGNGSSRYSPSQ CCCCCCCCCCCCCCC	18.68	23401153
282	Phosphorylation	GSVGNGSSRYSPSQN CCCCCCCCCCCCCCC	36.31	25159151
283	Phosphorylation	SVGNGSSRYSPSQNS CCCCCCCCCCCCCCC	37.33	32142685
284	Phosphorylation	VGNGSSRYSPSQNSP CCCCCCCCCCCCCCC	27.21	29255136
285	Phosphorylation	GNGSSRYSPSQNSPI CCCCCCCCCCCCCCC	19.57	29255136
287	Phosphorylation	GSSRYSPSQNSPIHH CCCCCCCCCCCCCCC	35.73	29255136
288	Phosphorylation	SSRYSPSQNSPIHHI CCCCCCCCCCCCCCC	58.78	32142685
290	Phosphorylation	RYSPSQNSPIHHIPS CCCCCCCCCCCCCCC	20.00	29255136
297	Phosphorylation	SPIHHIPSRRSPAKT CCCCCCCCCCCCCCC	39.46	23927012
300	Phosphorylation	HHIPSRRSPAKTIAP CCCCCCCCCCCCCCC	28.26	20201521
303	Acetylation	PSRRSPAKTIAPQNA CCCCCCCCCCCCCCC	43.79	25953088
304	Phosphorylation	SRRSPAKTIAPQNAP CCCCCCCCCCCCCCC	25.20	27174698
315	Phosphorylation	QNAPRDESRGRSSFY CCCCCCCCCCCCCCC	44.30	23401153
319	Phosphorylation	RDESRGRSSFYPDGG CCCCCCCCCCCCCCC	27.85	23401153
320	Phosphorylation	DESRGRSSFYPDGGD CCCCCCCCCCCCCCC	27.69	23927012
322	Nitration	SRGRSSFYPDGGDQE CCCCCCCCCCCCCHH	11.45	-
322	Phosphorylation	SRGRSSFYPDGGDQE CCCCCCCCCCCCCHH	11.45	28152594
330	Phosphorylation	PDGGDQETAKTGKFL CCCCCHHHHHCCCHH	28.02	25159151
330	Ubiquitination	PDGGDQETAKTGKFL CCCCCHHHHHCCCHH	28.02	32015554
330 (in isoform 2)	Ubiquitination	-	28.02	21890473
330 (in isoform 3)	Ubiquitination	-	28.02	21890473
332	Sumoylation	GGDQETAKTGKFLKR CCCHHHHHCCCHHHH	66.29	-
332	Acetylation	GGDQETAKTGKFLKR CCCHHHHHCCCHHHH	66.29	25953088
332	Sumoylation	GGDQETAKTGKFLKR CCCHHHHHCCCHHHH	66.29	28112733
332	Ubiquitination	GGDQETAKTGKFLKR CCCHHHHHCCCHHHH	66.29	21906983
332 (in isoform 1)	Ubiquitination	-	66.29	21890473
332 (in isoform 4)	Ubiquitination	-	66.29	21890473
333	Acetylation	GDQETAKTGKFLKRF CCHHHHHCCCHHHHC	43.04	19608861
333	O-linked_Glycosylation	GDQETAKTGKFLKRF CCHHHHHCCCHHHHC	43.04	23301498
333	Ubiquitination	GDQETAKTGKFLKRF CCHHHHHCCCHHHHC	43.04	22817900
335	Sumoylation	QETAKTGKFLKRFTD HHHHHCCCHHHHCCC	53.40	-
335	Acetylation	QETAKTGKFLKRFTD HHHHHCCCHHHHCCC	53.40	25825284
335	Sumoylation	QETAKTGKFLKRFTD HHHHHCCCHHHHCCC	53.40	19608861
335	Ubiquitination	QETAKTGKFLKRFTD HHHHHCCCHHHHCCC	53.40	22817900
339 (in isoform 4)	Phosphorylation	-	41.67	30266825
341	Phosphorylation	GKFLKRFTDEESRVF CCHHHHCCCCCCCEE	46.68	23401153
342	Ubiquitination	KFLKRFTDEESRVFL CHHHHCCCCCCCEEE	55.76	22817900
344	Ubiquitination	LKRFTDEESRVFLLD HHHCCCCCCCEEEEE	46.81	22817900
345	Phosphorylation	KRFTDEESRVFLLDR HHCCCCCCCEEEEEC	31.53	28176443
352	Methylation	SRVFLLDRGNTRDKE CCEEEEECCCCCCHH	39.98	-
352 (in isoform 4)	Phosphorylation	-	39.98	25849741
355	Phosphorylation	FLLDRGNTRDKEASK EEEECCCCCCHHHHH	42.97	23403867
356	Phosphorylation	LLDRGNTRDKEASKE EEECCCCCCHHHHHH	57.93	32142685
358	Phosphorylation	DRGNTRDKEASKEKG ECCCCCCHHHHHHHC	52.46	32142685
360	Ubiquitination	GNTRDKEASKEKGSE CCCCCHHHHHHHCCC	31.48	24816145
362	Ubiquitination	TRDKEASKEKGSEKG CCCHHHHHHHCCCCC	71.18	24816145
363	Ubiquitination	RDKEASKEKGSEKGR CCHHHHHHHCCCCCC	61.22	29967540
366	Phosphorylation	EASKEKGSEKGRAEG HHHHHHCCCCCCCCC	47.40	23312004
373	Neddylation	SEKGRAEGEWEDQEA CCCCCCCCCCCCHHH	44.31	32015554
373	Ubiquitination	SEKGRAEGEWEDQEA CCCCCCCCCCCCHHH	44.31	32015554
375	Neddylation	KGRAEGEWEDQEALD CCCCCCCCCCHHHHH	25.89	32015554
375	Ubiquitination	KGRAEGEWEDQEALD CCCCCCCCCCHHHHH	25.89	32015554
377	Ubiquitination	RAEGEWEDQEALDYF CCCCCCCCHHHHHHH	53.33	32015554
381	Phosphorylation	EWEDQEALDYFSDKE CCCCHHHHHHHCCCH	5.58	32142685
383	Phosphorylation	EDQEALDYFSDKESG CCHHHHHHHCCCHHC	13.06	23927012
385	Phosphorylation	QEALDYFSDKESGKQ HHHHHHHCCCHHCCC	41.36	19664994
389	Phosphorylation	DYFSDKESGKQKFND HHHCCCHHCCCCCCC	57.96	22167270
392	Ubiquitination	SDKESGKQKFNDSEG CCCHHCCCCCCCCCC	60.13	21890473
394	Ubiquitination	KESGKQKFNDSEGDD CHHCCCCCCCCCCCC	13.07	21890473
394 (in isoform 4)	Ubiquitination	-	13.07	21890473
395	Phosphorylation	ESGKQKFNDSEGDDT HHCCCCCCCCCCCCC	59.96	32142685
397	Phosphorylation	GKQKFNDSEGDDTEE CCCCCCCCCCCCCCC	44.58	19664994
400	Phosphorylation	KFNDSEGDDTEETED CCCCCCCCCCCCCHH	56.45	32142685
402	Phosphorylation	NDSEGDDTEETEDYR CCCCCCCCCCCHHHH	40.22	22167270
405	Phosphorylation	EGDDTEETEDYRQFR CCCCCCCCHHHHHHH	28.11	22167270
405	Ubiquitination	EGDDTEETEDYRQFR CCCCCCCCHHHHHHH	28.11	16196087
407	Ubiquitination	DDTEETEDYRQFRKS CCCCCCHHHHHHHHH	51.87	16196087
408	Phosphorylation	DTEETEDYRQFRKSV CCCCCHHHHHHHHHH	10.49	23927012
411	Ubiquitination	ETEDYRQFRKSVLAD CCHHHHHHHHHHHHH	8.64	29967540
413	Sumoylation	EDYRQFRKSVLADQG HHHHHHHHHHHHHCC	46.32	-
413	2-Hydroxyisobutyrylation	EDYRQFRKSVLADQG HHHHHHHHHHHHHCC	46.32	-
413	Sumoylation	EDYRQFRKSVLADQG HHHHHHHHHHHHHCC	46.32	28112733
413	Ubiquitination	EDYRQFRKSVLADQG HHHHHHHHHHHHHCC	46.32	29967540
414	Phosphorylation	DYRQFRKSVLADQGK HHHHHHHHHHHHCCC	20.36	29255136
418	Ubiquitination	FRKSVLADQGKSFAT HHHHHHHHCCCCHHC	54.31	21890473
419	Acetylation	RKSVLADQGKSFATA HHHHHHHCCCCHHCC	56.45	19608861
419	Ubiquitination	RKSVLADQGKSFATA HHHHHHHCCCCHHCC	56.45	33845483
419 (in isoform 2)	Ubiquitination	-	56.45	21890473
419 (in isoform 3)	Ubiquitination	-	56.45	21890473
420	Ubiquitination	KSVLADQGKSFATAS HHHHHHCCCCHHCCC	28.29	23000965
420 (in isoform 4)	Ubiquitination	-	28.29	21890473
421	Sumoylation	SVLADQGKSFATASH HHHHHCCCCHHCCCC	36.45	-
421	2-Hydroxyisobutyrylation	SVLADQGKSFATASH HHHHHCCCCHHCCCC	36.45	-
421	Acetylation	SVLADQGKSFATASH HHHHHCCCCHHCCCC	36.45	23954790
421	Sumoylation	SVLADQGKSFATASH HHHHHCCCCHHCCCC	36.45	28112733
421	Ubiquitination	SVLADQGKSFATASH HHHHHCCCCHHCCCC	36.45	22817900
421 (in isoform 1)	Ubiquitination	-	36.45	21890473
422	Phosphorylation	VLADQGKSFATASHR HHHHCCCCHHCCCCC	27.26	23401153
424	Ubiquitination	ADQGKSFATASHRNT HHCCCCHHCCCCCCC	14.89	23000965
425	Phosphorylation	DQGKSFATASHRNTE HCCCCHHCCCCCCCH	27.04	23403867
426	Ubiquitination	QGKSFATASHRNTEE CCCCHHCCCCCCCHH	10.42	23000965
427	Phosphorylation	GKSFATASHRNTEEE CCCHHCCCCCCCHHH	20.73	23401153
429	Methylation	SFATASHRNTEEEGL CHHCCCCCCCHHHCC	49.63	-
431	Phosphorylation	ATASHRNTEEEGLKY HCCCCCCCHHHCCEE	44.74	25159151
435	Acetylation	HRNTEEEGLKYKSKV CCCCHHHCCEECCEE	30.65	19608861
435	Ubiquitination	HRNTEEEGLKYKSKV CCCCHHHCCEECCEE	30.65	32015554
437	Sumoylation	NTEEEGLKYKSKVSL CCHHHCCEECCEEEC	62.58	-
437	Acetylation	NTEEEGLKYKSKVSL CCHHHCCEECCEEEC	62.58	19608861
437	Methylation	NTEEEGLKYKSKVSL CCHHHCCEECCEEEC	62.58	19608861
437	Sumoylation	NTEEEGLKYKSKVSL CCHHHCCEECCEEEC	62.58	28112733
437	Ubiquitination	NTEEEGLKYKSKVSL CCHHHCCEECCEEEC	62.58	32015554
438	Phosphorylation	TEEEGLKYKSKVSLK CHHHCCEECCEEECC	26.07	28152594
439	Acetylation	EEEGLKYKSKVSLKG HHHCCEECCEEECCC	42.06	7661971
439	Ubiquitination	EEEGLKYKSKVSLKG HHHCCEECCEEECCC	42.06	27667366
440	Phosphorylation	EEGLKYKSKVSLKGN HHCCEECCEEECCCC	34.89	26074081
441	Ubiquitination	EGLKYKSKVSLKGNR HCCEECCEEECCCCC	31.52	27667366
442	Ubiquitination	GLKYKSKVSLKGNRE CCEECCEEECCCCCC	11.92	22817900
443	Phosphorylation	LKYKSKVSLKGNRES CEECCEEECCCCCCC	28.27	26074081
443	Ubiquitination	LKYKSKVSLKGNRES CEECCEEECCCCCCC	28.27	27667366
444	Ubiquitination	KYKSKVSLKGNRESD EECCEEECCCCCCCC	10.36	22817900
445	Acetylation	YKSKVSLKGNRESDG ECCEEECCCCCCCCC	46.78	25953088
445	Methylation	YKSKVSLKGNRESDG ECCEEECCCCCCCCC	46.78	-
445	Ubiquitination	YKSKVSLKGNRESDG ECCEEECCCCCCCCC	46.78	27667366
447	Ubiquitination	SKVSLKGNRESDGFR CEEECCCCCCCCCCH	42.85	21890473
449	Ubiquitination	VSLKGNRESDGFREE EECCCCCCCCCCHHH	58.12	21890473
449 (in isoform 4)	Ubiquitination	-	58.12	21890473
450	Phosphorylation	SLKGNRESDGFREEK ECCCCCCCCCCHHHH	39.53	29255136
457	Acetylation	SDGFREEKNYKLKET CCCCHHHHCEEEEEC	61.90	25953088
457	Sumoylation	SDGFREEKNYKLKET CCCCHHHHCEEEEEC	61.90	28112733
459	Phosphorylation	GFREEKNYKLKETGY CCHHHHCEEEEECEE	28.85	-
460	Ubiquitination	FREEKNYKLKETGYV CHHHHCEEEEECEEE	63.58	32015554
462	Sumoylation	EEKNYKLKETGYVVE HHHCEEEEECEEEEE	49.42	-
462	Sumoylation	EEKNYKLKETGYVVE HHHCEEEEECEEEEE	49.42	28112733
462	Ubiquitination	EEKNYKLKETGYVVE HHHCEEEEECEEEEE	49.42	32015554
464	Acetylation	KNYKLKETGYVVERP HCEEEEECEEEEECC	32.02	19608861
464	Phosphorylation	KNYKLKETGYVVERP HCEEEEECEEEEECC	32.02	19691289
464	Ubiquitination	KNYKLKETGYVVERP HCEEEEECEEEEECC	32.02	32015554
466	Phosphorylation	YKLKETGYVVERPST EEEEECEEEEECCCC	14.56	23403867
472	Phosphorylation	GYVVERPSTTKDKHK EEEEECCCCCCCCCC	55.73	25159151
473	Phosphorylation	YVVERPSTTKDKHKE EEEECCCCCCCCCCC	40.31	25159151
473	Ubiquitination	YVVERPSTTKDKHKE EEEECCCCCCCCCCC	40.31	29967540
474	Phosphorylation	VVERPSTTKDKHKEE EEECCCCCCCCCCCC	41.40	25159151
475	Acetylation	VERPSTTKDKHKEED EECCCCCCCCCCCCC	65.94	-
475	Ubiquitination	VERPSTTKDKHKEED EECCCCCCCCCCCCC	65.94	29967540
483	Phosphorylation	DKHKEEDKNSERITV CCCCCCCCCCCCCEE	66.70	32142685
485	Phosphorylation	HKEEDKNSERITVKK CCCCCCCCCCCEEEE	33.71	19664994
486	Phosphorylation	KEEDKNSERITVKKE CCCCCCCCCCEEEEC	58.45	32142685
487	Phosphorylation	EEDKNSERITVKKET CCCCCCCCCEEEECC	29.69	32142685
488	Phosphorylation	EDKNSERITVKKETQ CCCCCCCCEEEECCC	4.57	32142685
489	Phosphorylation	DKNSERITVKKETQS CCCCCCCEEEECCCC	32.28	28450419
491	Sumoylation	NSERITVKKETQSPE CCCCCEEEECCCCHH	35.92	-
491	Sumoylation	NSERITVKKETQSPE CCCCCEEEECCCCHH	35.92	28112733
492	Sumoylation	SERITVKKETQSPEQ CCCCEEEECCCCHHH	62.75	28112733
494	Phosphorylation	RITVKKETQSPEQVK CCEEEECCCCHHHHH	43.13	22167270
496	Phosphorylation	TVKKETQSPEQVKSE EEEECCCCHHHHHHH	37.51	29255136
501	Sumoylation	TQSPEQVKSEKLKDL CCCHHHHHHHHHHHH	53.22	-
501	Acetylation	TQSPEQVKSEKLKDL CCCHHHHHHHHHHHH	53.22	26051181
501	Sumoylation	TQSPEQVKSEKLKDL CCCHHHHHHHHHHHH	53.22	28112733
501	Ubiquitination	TQSPEQVKSEKLKDL CCCHHHHHHHHHHHH	53.22	24816145
502	Phosphorylation	QSPEQVKSEKLKDLF CCHHHHHHHHHHHHH	40.90	23927012
503	Ubiquitination	SPEQVKSEKLKDLFD CHHHHHHHHHHHHHC	57.60	24816145
506	Acetylation	QVKSEKLKDLFDYSP HHHHHHHHHHHCCCC	64.55	26051181
509	Phosphorylation	SEKLKDLFDYSPPLH HHHHHHHHCCCCCCH	13.70	32142685
510	Ubiquitination	EKLKDLFDYSPPLHK HHHHHHHCCCCCCHH	50.74	32015554
511	Phosphorylation	KLKDLFDYSPPLHKN HHHHHHCCCCCCHHC	18.75	23927012
512	Phosphorylation	LKDLFDYSPPLHKNL HHHHHCCCCCCHHCC	23.14	29255136
515	Phosphorylation	LFDYSPPLHKNLDAR HHCCCCCCHHCCCHH	11.59	32645325
515	Ubiquitination	LFDYSPPLHKNLDAR HHCCCCCCHHCCCHH	11.59	21890473
515 (in isoform 2)	Ubiquitination	-	11.59	21890473
515 (in isoform 3)	Ubiquitination	-	11.59	21890473
516	Phosphorylation	FDYSPPLHKNLDARE HCCCCCCHHCCCHHH	23.80	32645325
517	2-Hydroxyisobutyrylation	DYSPPLHKNLDAREK CCCCCCHHCCCHHHH	67.88	-
517	Phosphorylation	DYSPPLHKNLDAREK CCCCCCHHCCCHHHH	67.88	32645325
517	Ubiquitination	DYSPPLHKNLDAREK CCCCCCHHCCCHHHH	67.88	22817900
517 (in isoform 1)	Ubiquitination	-	67.88	21890473
525	Phosphorylation	NLDAREKSTFREESP CCCHHHHCCCCCCCC	28.20	23927012
526	Phosphorylation	LDAREKSTFREESPL CCHHHHCCCCCCCCC	37.47	23927012
529	Phosphorylation	REKSTFREESPLRIK HHHCCCCCCCCCEEE	59.65	32142685
531	Phosphorylation	KSTFREESPLRIKMI HCCCCCCCCCEEEEE	25.20	29255136
534	Ubiquitination	FREESPLRIKMIASD CCCCCCCEEEEEECC	29.84	29967540
536	Sumoylation	EESPLRIKMIASDSH CCCCCEEEEEECCCC	20.16	-
536	2-Hydroxyisobutyrylation	EESPLRIKMIASDSH CCCCCEEEEEECCCC	20.16	-
536	Sumoylation	EESPLRIKMIASDSH CCCCCEEEEEECCCC	20.16	28112733
536	Ubiquitination	EESPLRIKMIASDSH CCCCCEEEEEECCCC	20.16	29967540
540	Phosphorylation	LRIKMIASDSHRPEV CEEEEEECCCCCCCC	28.81	25159151
542	Phosphorylation	IKMIASDSHRPEVKL EEEEECCCCCCCCEE	20.92	26074081
546	Neddylation	ASDSHRPEVKLKMAP ECCCCCCCCEEEEEC	52.84	32015554
546	Ubiquitination	ASDSHRPEVKLKMAP ECCCCCCCCEEEEEC	52.84	32015554
548	Sumoylation	DSHRPEVKLKMAPVP CCCCCCCEEEEECCC	40.50	-
548	Acetylation	DSHRPEVKLKMAPVP CCCCCCCEEEEECCC	40.50	25953088
548	Neddylation	DSHRPEVKLKMAPVP CCCCCCCEEEEECCC	40.50	32015554
548	Sumoylation	DSHRPEVKLKMAPVP CCCCCCCEEEEECCC	40.50	28112733
548	Ubiquitination	DSHRPEVKLKMAPVP CCCCCCCEEEEECCC	40.50	32015554
550	Sumoylation	HRPEVKLKMAPVPLD CCCCCEEEEECCCCC	27.57	-
550	Sumoylation	HRPEVKLKMAPVPLD CCCCCEEEEECCCCC	27.57	28112733
550	Ubiquitination	HRPEVKLKMAPVPLD CCCCCEEEEECCCCC	27.57	32015554
551	Sulfoxidation	RPEVKLKMAPVPLDD CCCCEEEEECCCCCC	8.05	28183972
559	Phosphorylation	APVPLDDSNRPASLT ECCCCCCCCCCCCCC	34.11	23401153
564	Phosphorylation	DDSNRPASLTKDRLL CCCCCCCCCCHHHHH	38.97	30266825
565	Ubiquitination	DSNRPASLTKDRLLA CCCCCCCCCHHHHHH	8.19	21890473
565 (in isoform 2)	Ubiquitination	-	8.19	21890473
565 (in isoform 3)	Ubiquitination	-	8.19	21890473
566	Phosphorylation	SNRPASLTKDRLLAS CCCCCCCCHHHHHHH	28.53	30266825
567	2-Hydroxyisobutyrylation	NRPASLTKDRLLAST CCCCCCCHHHHHHHH	46.26	-
567	Acetylation	NRPASLTKDRLLAST CCCCCCCHHHHHHHH	46.26	26051181
567	Malonylation	NRPASLTKDRLLAST CCCCCCCHHHHHHHH	46.26	32601280
567	Methylation	NRPASLTKDRLLAST CCCCCCCHHHHHHHH	46.26	-
567	Sumoylation	NRPASLTKDRLLAST CCCCCCCHHHHHHHH	46.26	28112733
567	Ubiquitination	NRPASLTKDRLLAST CCCCCCCHHHHHHHH	46.26	22817900
567 (in isoform 1)	Ubiquitination	-	46.26	21890473
573	Phosphorylation	TKDRLLASTLVHSVK CHHHHHHHHHHHHHH	23.42	26055452
574	Phosphorylation	KDRLLASTLVHSVKK HHHHHHHHHHHHHHH	27.48	25159151
578	Phosphorylation	LASTLVHSVKKEQEF HHHHHHHHHHHHHHH	28.31	29255136
578	Ubiquitination	LASTLVHSVKKEQEF HHHHHHHHHHHHHHH	28.31	16196087
580	Sumoylation	STLVHSVKKEQEFRS HHHHHHHHHHHHHHH	54.32	-
580	2-Hydroxyisobutyrylation	STLVHSVKKEQEFRS HHHHHHHHHHHHHHH	54.32	-
580	Acetylation	STLVHSVKKEQEFRS HHHHHHHHHHHHHHH	54.32	25953088
580	Sumoylation	STLVHSVKKEQEFRS HHHHHHHHHHHHHHH	54.32	25114211
580	Ubiquitination	STLVHSVKKEQEFRS HHHHHHHHHHHHHHH	54.32	16196087
587	Phosphorylation	KKEQEFRSIFDHIKL HHHHHHHHHHHHCCC	32.69	19664995
591	Ubiquitination	EFRSIFDHIKLPQAS HHHHHHHHCCCCCCC	14.34	23000965
591 (in isoform 2)	Ubiquitination	-	14.34	21890473
591 (in isoform 3)	Ubiquitination	-	14.34	21890473
593	2-Hydroxyisobutyrylation	RSIFDHIKLPQASKS HHHHHHCCCCCCCCC	51.17	-
593	Acetylation	RSIFDHIKLPQASKS HHHHHHCCCCCCCCC	51.17	25953088
593	Malonylation	RSIFDHIKLPQASKS HHHHHHCCCCCCCCC	51.17	26320211
593	Sumoylation	RSIFDHIKLPQASKS HHHHHHCCCCCCCCC	51.17	28112733
593	Ubiquitination	RSIFDHIKLPQASKS HHHHHHCCCCCCCCC	51.17	23000965
593 (in isoform 1)	Ubiquitination	-	51.17	21890473
597	Ubiquitination	DHIKLPQASKSTSES HHCCCCCCCCCCCHH	19.58	23000965
599	Sumoylation	IKLPQASKSTSESFI CCCCCCCCCCCHHHH	61.85	28112733
599	Ubiquitination	IKLPQASKSTSESFI CCCCCCCCCCCHHHH	61.85	23000965
600	Phosphorylation	KLPQASKSTSESFIQ CCCCCCCCCCHHHHH	34.37	20068231
601	Phosphorylation	LPQASKSTSESFIQH CCCCCCCCCHHHHHH	40.00	29523821
602	Phosphorylation	PQASKSTSESFIQHI CCCCCCCCHHHHHHH	38.03	20068231
604	Phosphorylation	ASKSTSESFIQHIVS CCCCCCHHHHHHHHH	27.67	20068231
615	Ubiquitination	HIVSLVHHVKEQYFK HHHHHHHHHHHHHHH	25.51	22817900
617	Ubiquitination	VSLVHHVKEQYFKSA HHHHHHHHHHHHHHH	34.44	22817900
620	Ubiquitination	VHHVKEQYFKSAAMT HHHHHHHHHHHHHHH	17.67	21890473
620 (in isoform 2)	Ubiquitination	-	17.67	21890473
620 (in isoform 3)	Ubiquitination	-	17.67	21890473
622	Methylation	HVKEQYFKSAAMTLN HHHHHHHHHHHHHHH	33.96	-
622	Sumoylation	HVKEQYFKSAAMTLN HHHHHHHHHHHHHHH	33.96	28112733
622	Ubiquitination	HVKEQYFKSAAMTLN HHHHHHHHHHHHHHH	33.96	22817900
622 (in isoform 1)	Ubiquitination	-	33.96	21890473
633	Phosphorylation	MTLNERFTSYQKATE HHHHHHHHHHHHHHH	32.52	26074081
634	Phosphorylation	TLNERFTSYQKATEE HHHHHHHHHHHHHHH	23.89	26074081
635	Acetylation	LNERFTSYQKATEEH HHHHHHHHHHHHHHH	15.81	19608861
635	Phosphorylation	LNERFTSYQKATEEH HHHHHHHHHHHHHHH	15.81	26074081
635	Ubiquitination	LNERFTSYQKATEEH HHHHHHHHHHHHHHH	15.81	32015554
637	2-Hydroxyisobutyrylation	ERFTSYQKATEEHST HHHHHHHHHHHHHCC	49.39	-
637	Acetylation	ERFTSYQKATEEHST HHHHHHHHHHHHHCC	49.39	19608861
637	Ubiquitination	ERFTSYQKATEEHST HHHHHHHHHHHHHCC	49.39	33845483
639	Phosphorylation	FTSYQKATEEHSTRQ HHHHHHHHHHHCCCC	49.28	24732914
643	Phosphorylation	QKATEEHSTRQKSPE HHHHHHHCCCCCCHH	28.68	24732914
644	Phosphorylation	KATEEHSTRQKSPEI HHHHHHCCCCCCHHH	38.74	24732914
648	Phosphorylation	EHSTRQKSPEIHRRI HHCCCCCCHHHHHHC	21.30	22167270
656	Phosphorylation	PEIHRRIDISPSTLR HHHHHHCCCCHHHHH	33.24	32142685
658	Phosphorylation	IHRRIDISPSTLRKH HHHHCCCCHHHHHHH	14.73	19664994
659	Phosphorylation	HRRIDISPSTLRKHT HHHCCCCHHHHHHHH	31.50	32142685
660	Phosphorylation	RRIDISPSTLRKHTR HHCCCCHHHHHHHHH	33.03	22167270
661	Phosphorylation	RIDISPSTLRKHTRL HCCCCHHHHHHHHHH	33.69	22167270
666	Phosphorylation	PSTLRKHTRLAGEER HHHHHHHHHHCCCCH	30.34	26074081
667	Ubiquitination	STLRKHTRLAGEERV HHHHHHHHHCCCCHH	23.43	22817900
668	Ubiquitination	TLRKHTRLAGEERVF HHHHHHHHCCCCHHC	8.25	32015554
669	Ubiquitination	LRKHTRLAGEERVFK HHHHHHHCCCCHHCC	21.76	22817900
670	Ubiquitination	RKHTRLAGEERVFKE HHHHHHCCCCHHCCH	41.72	21890473
671	Ubiquitination	KHTRLAGEERVFKEE HHHHHCCCCHHCCHH	36.70	22817900
672	Ubiquitination	HTRLAGEERVFKEEN HHHHCCCCHHCCHHH	53.91	21890473
672 (in isoform 4)	Ubiquitination	-	53.91	21890473
674	Ubiquitination	RLAGEERVFKEENQK HHCCCCHHCCHHHHC	10.20	24816145
676	Sumoylation	AGEERVFKEENQKGD CCCCHHCCHHHHCCC	62.35	-
676	Sumoylation	AGEERVFKEENQKGD CCCCHHCCHHHHCCC	62.35	28112733
676	Ubiquitination	AGEERVFKEENQKGD CCCCHHCCHHHHCCC	62.35	24816145
681	Acetylation	VFKEENQKGDKKLRC HCCHHHHCCCCEECC	79.32	25953088
684	Acetylation	EENQKGDKKLRCDSA HHHHCCCCEECCCHH	63.48	7674301
685	Acetylation	ENQKGDKKLRCDSAD HHHCCCCEECCCHHH	46.00	12436955
687	Ubiquitination	QKGDKKLRCDSADLR HCCCCEECCCHHHHH	30.95	32015554
688	Phosphorylation	KGDKKLRCDSADLRH CCCCEECCCHHHHHH	7.60	32645325
689	Phosphorylation	GDKKLRCDSADLRHD CCCEECCCHHHHHHH	40.19	32645325
689	Ubiquitination	GDKKLRCDSADLRHD CCCEECCCHHHHHHH	40.19	32015554
690	Phosphorylation	DKKLRCDSADLRHDI CCEECCCHHHHHHHH	27.58	25159151
711	Phosphorylation	RSKERGDSKGSRESS HHHHHCCCCCCCCCC	41.56	20068231
714	Phosphorylation	ERGDSKGSRESSGSR HHCCCCCCCCCCCCC	36.29	30576142
717	Phosphorylation	DSKGSRESSGSRKQE CCCCCCCCCCCCCCC	38.60	30576142
718	Phosphorylation	SKGSRESSGSRKQEK CCCCCCCCCCCCCCC	35.71	20068231
718	Ubiquitination	SKGSRESSGSRKQEK CCCCCCCCCCCCCCC	35.71	29967540
720	Phosphorylation	GSRESSGSRKQEKTP CCCCCCCCCCCCCCC	37.95	20068231
726	Phosphorylation	GSRKQEKTPKDYKEY CCCCCCCCCCHHHHH	34.51	20068231
730	Phosphorylation	QEKTPKDYKEYKSYK CCCCCCHHHHHHHHC	16.31	29438985
731	Sumoylation	EKTPKDYKEYKSYKD CCCCCHHHHHHHHCC	65.78	-
731	Sumoylation	EKTPKDYKEYKSYKD CCCCCHHHHHHHHCC	65.78	-
733	Phosphorylation	TPKDYKEYKSYKDDS CCCHHHHHHHHCCCC	10.90	-
735	Phosphorylation	KDYKEYKSYKDDSKH CHHHHHHHHCCCCCH	36.19	21601212
736	Ubiquitination	DYKEYKSYKDDSKHK HHHHHHHHCCCCCHH	17.81	32015554
737	Ubiquitination	YKEYKSYKDDSKHKR HHHHHHHCCCCCHHH	63.25	32015554
738	Ubiquitination	KEYKSYKDDSKHKRE HHHHHHCCCCCHHHH	58.12	32015554
740	Phosphorylation	YKSYKDDSKHKREQD HHHHCCCCCHHHHHH	46.95	21601212
749	Phosphorylation	HKREQDHSRSSSSSA HHHHHHCCCCCCCCC	41.99	23898821
751	Phosphorylation	REQDHSRSSSSSASP HHHHCCCCCCCCCCC	37.27	28176443
752	Phosphorylation	EQDHSRSSSSSASPS HHHCCCCCCCCCCCC	32.88	28176443
753	Phosphorylation	QDHSRSSSSSASPSS HHCCCCCCCCCCCCC	29.56	25159151
754	Phosphorylation	DHSRSSSSSASPSSP HCCCCCCCCCCCCCC	31.69	28176443
755	Phosphorylation	HSRSSSSSASPSSPS CCCCCCCCCCCCCCC	34.41	20044836
757	Phosphorylation	RSSSSSASPSSPSSR CCCCCCCCCCCCCHH	27.54	20044836
759	Phosphorylation	SSSSASPSSPSSREE CCCCCCCCCCCHHHH	53.00	23401153
760	Phosphorylation	SSSASPSSPSSREEK CCCCCCCCCCHHHHH	31.99	25159151
762	Phosphorylation	SASPSSPSSREEKES CCCCCCCCHHHHHHH	43.93	30278072
763	Phosphorylation	ASPSSPSSREEKESK CCCCCCCHHHHHHHH	47.28	30278072
769	Phosphorylation	SSREEKESKKEREEE CHHHHHHHHHHHHHH	61.16	27174698
778	Sumoylation	KEREEEFKTHHEMKE HHHHHHHHHHHHHHH	50.67	-
778	Methylation	KEREEEFKTHHEMKE HHHHHHHHHHHHHHH	50.67	-
778	Sumoylation	KEREEEFKTHHEMKE HHHHHHHHHHHHHHH	50.67	28112733
784	Sumoylation	FKTHHEMKEYSGFAG HHHHHHHHHHHCCCC	50.98	28112733
786	Phosphorylation	THHEMKEYSGFAGVS HHHHHHHHHCCCCCC	14.47	22817900
787	Phosphorylation	HHEMKEYSGFAGVSR HHHHHHHHCCCCCCC	28.64	28348404
793	Phosphorylation	YSGFAGVSRPRGTFF HHCCCCCCCCCCCEE	35.33	28348404
794	Dimethylation	SGFAGVSRPRGTFFR HCCCCCCCCCCCEEE	23.64	-
794	Methylation	SGFAGVSRPRGTFFR HCCCCCCCCCCCEEE	23.64	-
796	Dimethylation	FAGVSRPRGTFFRIR CCCCCCCCCCEEEEE	56.53	-
796	Methylation	FAGVSRPRGTFFRIR CCCCCCCCCCEEEEE	56.53	-
803	Citrullination	RGTFFRIRGRGRARG CCCEEEEECCCCCCE	25.21	-
803	Citrullination	RGTFFRIRGRGRARG CCCEEEEECCCCCCE	25.21	-
809	Dimethylation	IRGRGRARGVFAGTN EECCCCCCEEEECCC	40.21	-
809	Methylation	IRGRGRARGVFAGTN EECCCCCCEEEECCC	40.21	24129315
815	Phosphorylation	ARGVFAGTNTGPNNS CCEEEECCCCCCCCC	26.61	26552605
817	Phosphorylation	GVFAGTNTGPNNSNT EEEECCCCCCCCCCC	54.58	26552605
822	Phosphorylation	TNTGPNNSNTTFQKR CCCCCCCCCCCCCCC	42.04	26552605
824	Phosphorylation	TGPNNSNTTFQKRPK CCCCCCCCCCCCCCC	28.89	26552605
825	Phosphorylation	GPNNSNTTFQKRPKE CCCCCCCCCCCCCCH	28.46	26552605
831	Sumoylation	TTFQKRPKEEEWDPE CCCCCCCCHHCCCCC	80.11	-
831	Sumoylation	TTFQKRPKEEEWDPE CCCCCCCCHHCCCCC	80.11	25114211
839	Phosphorylation	EEEWDPEYTPKSKKY HHCCCCCCCCCCCCE	33.46	30266825
840	Phosphorylation	EEWDPEYTPKSKKYF HCCCCCCCCCCCCEE	23.68	19664994
840	Ubiquitination	EEWDPEYTPKSKKYF HCCCCCCCCCCCCEE	23.68	32015554
841	Ubiquitination	EWDPEYTPKSKKYFL CCCCCCCCCCCCEEC	37.71	32015554
842	Ubiquitination	WDPEYTPKSKKYFLH CCCCCCCCCCCEECC	68.08	22817900
843	Phosphorylation	DPEYTPKSKKYFLHD CCCCCCCCCCEECCC	35.27	26074081
843	Ubiquitination	DPEYTPKSKKYFLHD CCCCCCCCCCEECCC	35.27	21890473
843 (in isoform 2)	Ubiquitination	-	35.27	21890473
844	Ubiquitination	PEYTPKSKKYFLHDD CCCCCCCCCEECCCC	58.58	22817900
845	Sumoylation	EYTPKSKKYFLHDDR CCCCCCCCEECCCCC	48.61	-
845	Sumoylation	EYTPKSKKYFLHDDR CCCCCCCCEECCCCC	48.61	-
845	Ubiquitination	EYTPKSKKYFLHDDR CCCCCCCCEECCCCC	48.61	22817900
845 (in isoform 1)	Ubiquitination	-	48.61	21890473
846	Phosphorylation	YTPKSKKYFLHDDRD CCCCCCCEECCCCCC	18.34	-
858	Phosphorylation	DRDDGVDYWAKRGRG CCCCCCCHHHHCCCC	12.59	27642862
860	Ubiquitination	DDGVDYWAKRGRGRG CCCCCHHHHCCCCCC	5.85	32015554
861	Ubiquitination	DGVDYWAKRGRGRGT CCCCHHHHCCCCCCC	41.04	32015554
862	Ubiquitination	GVDYWAKRGRGRGTF CCCHHHHCCCCCCCC	32.09	32015554
881	Phosphorylation	GRFNFKKSGSSPKWT CCCCCCCCCCCCCCC	44.49	23927012
883	Phosphorylation	FNFKKSGSSPKWTHD CCCCCCCCCCCCCCC	51.03	23927012
884	Phosphorylation	NFKKSGSSPKWTHDK CCCCCCCCCCCCCCC	33.74	23401153
888	Phosphorylation	SGSSPKWTHDKYQGD CCCCCCCCCCCCCCC	26.73	23927012
889	Ubiquitination	GSSPKWTHDKYQGDG CCCCCCCCCCCCCCC	28.57	29967540
891	Acetylation	SPKWTHDKYQGDGIV CCCCCCCCCCCCCCC	31.69	23954790
891	Ubiquitination	SPKWTHDKYQGDGIV CCCCCCCCCCCCCCC	31.69	29967540
892	Phosphorylation	PKWTHDKYQGDGIVE CCCCCCCCCCCCCCC	24.64	23927012
904	Phosphorylation	IVEDEEETMENNEEK CCCCHHHHHHCCHHH	32.82	26074081
909	Ubiquitination	EETMENNEEKKDRRK HHHHHCCHHHHHHHH	80.78	32015554
910	Ubiquitination	ETMENNEEKKDRRKE HHHHCCHHHHHHHHH	68.48	32015554
911	Acetylation	TMENNEEKKDRRKEE HHHCCHHHHHHHHHH	54.52	26051181
911	Sumoylation	TMENNEEKKDRRKEE HHHCCHHHHHHHHHH	54.52	28112733
911	Ubiquitination	TMENNEEKKDRRKEE HHHCCHHHHHHHHHH	54.52	32015554
912	Acetylation	MENNEEKKDRRKEEK HHCCHHHHHHHHHHH	60.80	26051181

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
80	Y	Phosphorylation	Kinase	SRC	P12931	PSP
81	Y	Phosphorylation	Kinase	SRC	P12931	PSP
93	Y	Phosphorylation	Kinase	SRC	P12931	PSP
150	Y	Phosphorylation	Kinase	SRC	P12931	PSP
284	Y	Phosphorylation	Kinase	SRC	P12931	PSP
408	Y	Phosphorylation	Kinase	SRC	P12931	PSP
531	S	Phosphorylation	Kinase	GSK3B	P49841	PSP
840	T	Phosphorylation	Kinase	CDK2	P24941	PSP

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BCLF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BCLF1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EMD_HUMAN	EMD	physical	15009215
RS9_HUMAN	RPS9	physical	26344197
TR150_HUMAN	THRAP3	physical	26344197
FMR1_HUMAN	FMR1	physical	26496610
ANM1_HUMAN	PRMT1	physical	26496610
DX39B_HUMAN	DDX39B	physical	26496610
FXR1_HUMAN	FXR1	physical	26496610
PABP2_HUMAN	PABPN1	physical	26496610
THOC5_HUMAN	THOC5	physical	26496610
SRSF9_HUMAN	SRSF9	physical	26496610
ABC3B_HUMAN	APOBEC3B	physical	26496610
ZC11A_HUMAN	ZC3H11A	physical	26496610
TR150_HUMAN	THRAP3	physical	26496610
THOC1_HUMAN	THOC1	physical	26496610
THOC4_HUMAN	ALYREF	physical	26496610
MINT_HUMAN	SPEN	physical	26496610
VIR_HUMAN	KIAA1429	physical	26496610
CHTOP_HUMAN	CHTOP	physical	26496610
PPHLN_HUMAN	PPHLN1	physical	26496610
CDK12_HUMAN	CDK12	physical	26496610
THOC2_HUMAN	THOC2	physical	26496610
THOC6_HUMAN	THOC6	physical	26496610
THOC7_HUMAN	THOC7	physical	26496610
PDIP3_HUMAN	POLDIP3	physical	26496610
THOC3_HUMAN	THOC3	physical	26496610
RMXL1_HUMAN	RBMXL1	physical	26496610

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-152; LYS-335; LYS-421;LYS-437 AND LYS-637, AND MASS SPECTROMETRY.
PubMed: 19608861

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-222; SER-290;SER-385; SER-397; THR-402; SER-512 AND THR-840, AND MASS SPECTROMETRY.
PubMed: 19690332

"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-648, AND MASSSPECTROMETRY.
PubMed: 19369195

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-222; SER-287;SER-290; SER-385; SER-397; THR-402; SER-512; SER-525; SER-658 ANDSER-757, AND MASS SPECTROMETRY.
PubMed: 19413330

"Large-scale phosphoproteome analysis of human liver tissue byenrichment and fractionation of phosphopeptides with strong anionexchange chromatography.";
Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D.,Zou H., Gu J.;
Proteomics 8:1346-1361(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177 AND SER-397, ANDMASS SPECTROMETRY.
PubMed: 18318008

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-181; SER-222;SER-264; SER-268; TYR-284; SER-290; THR-341; SER-385; SER-389;SER-397; THR-402; SER-512; SER-531; SER-578; SER-658 AND THR-840, ANDMASS SPECTROMETRY.
PubMed: 18669648

"Phosphorylation analysis of primary human T lymphocytes usingsequential IMAC and titanium oxide enrichment.";
Carrascal M., Ovelleiro D., Casas V., Gay M., Abian J.;
J. Proteome Res. 7:5167-5176(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-397, AND MASSSPECTROMETRY.
PubMed: 19367720

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-658, AND MASSSPECTROMETRY.
PubMed: 18220336

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-512 AND SER-531, ANDMASS SPECTROMETRY.
PubMed: 18187866

"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-397; SER-496;SER-512; SER-531; SER-658; SER-660 AND THR-661, AND MASS SPECTROMETRY.
PubMed: 19007248

"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry.";
Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-183; SER-198;SER-264; SER-268; SER-276; TYR-284; SER-285; SER-287; SER-290;SER-297; SER-315; SER-319; SER-320; SER-385; SER-397; THR-402;THR-405; TYR-408; SER-443; SER-450; THR-489; THR-494; SER-496;SER-502; TYR-511; SER-512; SER-525; THR-526; SER-531; SER-648;SER-658; THR-661; SER-711 AND SER-720, AND MASS SPECTROMETRY.
PubMed: 17287340

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-512; SER-531;SER-578; SER-658 AND THR-661, AND MASS SPECTROMETRY.
PubMed: 17924679

"Toward a global characterization of the phosphoproteome in prostatecancer cells: identification of phosphoproteins in the LNCaP cellline.";
Giorgianni F., Zhao Y., Desiderio D.M., Beranova-Giorgianni S.;
Electrophoresis 28:2027-2034(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-397, AND MASSSPECTROMETRY.
PubMed: 17487921

"Phosphoproteome analysis of the human mitotic spindle.";
Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.;
Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-222; SER-285; SER-290;SER-385; SER-496; SER-512; SER-658 AND THR-840, AND MASS SPECTROMETRY.
PubMed: 16565220

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-658, AND MASSSPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102; SER-104; SER-161;SER-177; SER-385; SER-397; THR-402; SER-450; SER-496; SER-512;SER-531; SER-648; SER-658 AND SER-690, AND MASS SPECTROMETRY.
PubMed: 17081983

"Global phosphoproteome of HT-29 human colon adenocarcinoma cells.";
Kim J.-E., Tannenbaum S.R., White F.M.;
J. Proteome Res. 4:1339-1346(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-531 AND SER-658, ANDMASS SPECTROMETRY.
PubMed: 16083285

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-119; SER-148; SER-151;SER-153; SER-177; SER-217; SER-222; SER-281; SER-397; SER-658 ANDSER-760, AND MASS SPECTROMETRY.
PubMed: 15302935