dbPTM

ZC11A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZC11A_HUMAN
UniProt AC	O75152
Protein Name	Zinc finger CCCH domain-containing protein 11A
Gene Name	ZC3H11A
Organism	Homo sapiens (Human).
Sequence Length	810
Subcellular Localization
Protein Description	Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex..
Protein Sequence	MPNQGEDCYFFFYSTCTKGDSCPFRHCEAAIGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPTGCQKLNCAFHHNRGRYVDGLFLPPSKTVLPTVPESPEEEVKASQLSVQQNKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVTSVRKPAVNIKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSLLLHPEPVPGPEKENVRTVVRTVTLSTKQGEEPLVRLSLTERLGKRKFSAGGDSDPPLKRSLAQRLGKKVEAPETNIDKTPKKAQVSKSLKERLGMSADPDNEDATDKVNKVGEIHVKTLEEILLERASQKRGELQTKLKTEGPSKTDDSTSGARSSSTIRIKTFSEVLAEKKHRQQEAERQKSKKDTTCIKLKIDSEIKKTVVLPPIVASRGQSEEPAGKTKSMQEVHIKTLEEIKLEKALRVQQSSESSTSSPSQHEATPGARRLLRITKRTGMKEEKNLQEGNEVDSQSSIRTEAKEASGETTGVDITKIQVKRCETMREKHMQKQQEREKSVLTPLRGDVASCNTQVAEKPVLTAVPGITRHLTKRLPTKSSQKVEVETSGIGDSLLNVKCAAQTLEKRGKAKPKVNVKPSVVKVVSSPKLAPKRKAVEMHAAVIAAVKPLSSSSVLQEPPAKKAAVAVVPLVSEDKSVTVPEAENPRDSLVLPPTQSSSDSSPPEVSGPSSSQMSMKTRRLSSASTGKPPLSVEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Ubiquitination	RCFRQVCRFRHMEID HHHHHHHHHHCCCCC	32.55	24816145
60	Sumoylation	RHMEIDKKRSEIPCY HCCCCCCCCCCCCCC	58.36	-
60	Sumoylation	RHMEIDKKRSEIPCY HCCCCCCCCCCCCCC	58.36	-
99	Ubiquitination	GLFLPPSKTVLPTVP CEEECCCCCCCCCCC	48.72	29967540
100	Phosphorylation	LFLPPSKTVLPTVPE EEECCCCCCCCCCCC	31.45	28464451
104	Phosphorylation	PSKTVLPTVPESPEE CCCCCCCCCCCCHHH	44.52	23927012
108	Phosphorylation	VLPTVPESPEEEVKA CCCCCCCCHHHHHHH	31.38	19664994
114	Sumoylation	ESPEEEVKASQLSVQ CCHHHHHHHHHHHHH	45.67	-
114	Sumoylation	ESPEEEVKASQLSVQ CCHHHHHHHHHHHHH	45.67	28112733
114	Ubiquitination	ESPEEEVKASQLSVQ CCHHHHHHHHHHHHH	45.67	29967540
116	Phosphorylation	PEEEVKASQLSVQQN HHHHHHHHHHHHHHH	26.41	17525332
119	Phosphorylation	EVKASQLSVQQNKLS HHHHHHHHHHHHCCC	15.39	24732914
124	Sumoylation	QLSVQQNKLSVQSNP HHHHHHHCCCCCCCC	37.49	-
124	Ubiquitination	QLSVQQNKLSVQSNP HHHHHHHCCCCCCCC	37.49	22817900
124	Sumoylation	QLSVQQNKLSVQSNP HHHHHHHCCCCCCCC	37.49	28112733
124	Acetylation	QLSVQQNKLSVQSNP HHHHHHHCCCCCCCC	37.49	25953088
126	Phosphorylation	SVQQNKLSVQSNPSP HHHHHCCCCCCCCCH	21.51	19691289
129	Phosphorylation	QNKLSVQSNPSPQLR HHCCCCCCCCCHHHH	48.86	22167270
132	Phosphorylation	LSVQSNPSPQLRSVM CCCCCCCCHHHHHEE	29.54	29255136
137	Phosphorylation	NPSPQLRSVMKVESS CCCHHHHHEEEEECC	34.85	26074081
140	Sumoylation	PQLRSVMKVESSENV HHHHHEEEEECCCCC	40.47	28112733
143	Phosphorylation	RSVMKVESSENVPSP HHEEEEECCCCCCCC	46.03	23927012
144	Phosphorylation	SVMKVESSENVPSPT HEEEEECCCCCCCCC	21.49	25850435
149	Phosphorylation	ESSENVPSPTHPPVV ECCCCCCCCCCCCEE	37.84	23927012
151	Phosphorylation	SENVPSPTHPPVVIN CCCCCCCCCCCEEEE	51.88	23927012
171	Phosphorylation	EDDDDQFSEEGDETK CCCCCCCCCCCCCCC	29.16	23927012
177	Phosphorylation	FSEEGDETKTPTLQP CCCCCCCCCCCCCCC	44.98	30278072
179	Phosphorylation	EEGDETKTPTLQPTP CCCCCCCCCCCCCCC	29.00	28464451
181	Phosphorylation	GDETKTPTLQPTPEV CCCCCCCCCCCCCCC	43.17	30266825
185	Phosphorylation	KTPTLQPTPEVHNGL CCCCCCCCCCCCCCE	21.08	30266825
185	Ubiquitination	KTPTLQPTPEVHNGL CCCCCCCCCCCCCCE	21.08	24816145
195	Phosphorylation	VHNGLRVTSVRKPAV CCCCEEEEEECCCCC	18.31	23186163
196	Phosphorylation	HNGLRVTSVRKPAVN CCCEEEEEECCCCCC	19.64	25159151
199	Ubiquitination	LRVTSVRKPAVNIKQ EEEEEECCCCCCCCC	34.86	29967540
215	Ubiquitination	ECLNFGIKTLEEIKS CHHHHCCHHHHHHHH	47.65	29967540
215	Acetylation	ECLNFGIKTLEEIKS CHHHHCCHHHHHHHH	47.65	26051181
221	Sumoylation	IKTLEEIKSKKMKEK CHHHHHHHHHHHHHH	60.55	-
221	Sumoylation	IKTLEEIKSKKMKEK CHHHHHHHHHHHHHH	60.55	-
221	Ubiquitination	IKTLEEIKSKKMKEK CHHHHHHHHHHHHHH	60.55	29967540
229	Phosphorylation	SKKMKEKSKKQGEGS HHHHHHHHHHCCCCC	46.29	-
231	Ubiquitination	KMKEKSKKQGEGSSG HHHHHHHHCCCCCCC	71.30	29967540
237	Phosphorylation	KKQGEGSSGVSSLLL HHCCCCCCCCHHHHC	54.81	28555341
241	Phosphorylation	EGSSGVSSLLLHPEP CCCCCCHHHHCCCCC	22.19	28555341
254	Ubiquitination	EPVPGPEKENVRTVV CCCCCCCCCCCEEEE	58.69	-
263	Phosphorylation	NVRTVVRTVTLSTKQ CCEEEEEEEEECCCC	13.26	23312004
265	Phosphorylation	RTVVRTVTLSTKQGE EEEEEEEEECCCCCC	17.87	29514088
267	Phosphorylation	VVRTVTLSTKQGEEP EEEEEEECCCCCCCC	24.96	29514088
268	Phosphorylation	VRTVTLSTKQGEEPL EEEEEECCCCCCCCE	30.42	29514088
269	Sumoylation	RTVTLSTKQGEEPLV EEEEECCCCCCCCEE	53.59	-
269	Sumoylation	RTVTLSTKQGEEPLV EEEEECCCCCCCCEE	53.59	-
269	Ubiquitination	RTVTLSTKQGEEPLV EEEEECCCCCCCCEE	53.59	33845483
269	Acetylation	RTVTLSTKQGEEPLV EEEEECCCCCCCCEE	53.59	25953088
279	Phosphorylation	EEPLVRLSLTERLGK CCCEEEEEHHHHHCC	23.76	25159151
281	Phosphorylation	PLVRLSLTERLGKRK CEEEEEHHHHHCCCC	18.71	27251275
286	Acetylation	SLTERLGKRKFSAGG EHHHHHCCCCCCCCC	57.94	20167786
288	Methylation	TERLGKRKFSAGGDS HHHHCCCCCCCCCCC	47.35	115978381
290	Phosphorylation	RLGKRKFSAGGDSDP HHCCCCCCCCCCCCH	29.10	29255136
295	Phosphorylation	KFSAGGDSDPPLKRS CCCCCCCCCHHHHHH	56.12	23927012
300	Methylation	GDSDPPLKRSLAQRL CCCCHHHHHHHHHHH	45.79	115978389
300	Ubiquitination	GDSDPPLKRSLAQRL CCCCHHHHHHHHHHH	45.79	33845483
300	2-Hydroxyisobutyrylation	GDSDPPLKRSLAQRL CCCCHHHHHHHHHHH	45.79	-
300	Acetylation	GDSDPPLKRSLAQRL CCCCHHHHHHHHHHH	45.79	25953088
310	Sumoylation	LAQRLGKKVEAPETN HHHHHCCCCCCCCCC	43.43	-
310	Sumoylation	LAQRLGKKVEAPETN HHHHHCCCCCCCCCC	43.43	-
310	Ubiquitination	LAQRLGKKVEAPETN HHHHHCCCCCCCCCC	43.43	29967540
310	Acetylation	LAQRLGKKVEAPETN HHHHHCCCCCCCCCC	43.43	26051181
316	Phosphorylation	KKVEAPETNIDKTPK CCCCCCCCCCCCCCC	36.09	30266825
320	Acetylation	APETNIDKTPKKAQV CCCCCCCCCCCHHHH	64.03	25953088
321	Phosphorylation	PETNIDKTPKKAQVS CCCCCCCCCCHHHHC	36.27	29255136
328	Phosphorylation	TPKKAQVSKSLKERL CCCHHHHCHHHHHHH	12.40	-
329	Ubiquitination	PKKAQVSKSLKERLG CCHHHHCHHHHHHHC	62.03	29967540
329	Acetylation	PKKAQVSKSLKERLG CCHHHHCHHHHHHHC	62.03	25953088
332	Ubiquitination	AQVSKSLKERLGMSA HHHCHHHHHHHCCCC	48.13	29967540
337	Sulfoxidation	SLKERLGMSADPDNE HHHHHHCCCCCCCCC	3.36	21406390
338	Phosphorylation	LKERLGMSADPDNED HHHHHCCCCCCCCCC	27.93	30108239
349	Ubiquitination	DNEDATDKVNKVGEI CCCCCCHHHHCCCEE	43.27	29967540
349	Acetylation	DNEDATDKVNKVGEI CCCCCCHHHHCCCEE	43.27	25953088
352	Ubiquitination	DATDKVNKVGEIHVK CCCHHHHCCCEEEHH	55.38	29967540
359	Ubiquitination	KVGEIHVKTLEEILL CCCEEEHHCHHHHHH	32.98	29967540
370	Phosphorylation	EILLERASQKRGELQ HHHHHHHHHHHCCHH	42.32	28112733
378	Phosphorylation	QKRGELQTKLKTEGP HHHCCHHHHHCCCCC	51.47	-
379	Ubiquitination	KRGELQTKLKTEGPS HHCCHHHHHCCCCCC	34.72	29967540
381	Sumoylation	GELQTKLKTEGPSKT CCHHHHHCCCCCCCC	46.19	-
381	Sumoylation	GELQTKLKTEGPSKT CCHHHHHCCCCCCCC	46.19	-
381	Ubiquitination	GELQTKLKTEGPSKT CCHHHHHCCCCCCCC	46.19	-
387	Ubiquitination	LKTEGPSKTDDSTSG HCCCCCCCCCCCCCC	60.14	24816145
391	Phosphorylation	GPSKTDDSTSGARSS CCCCCCCCCCCCCCC	27.55	21712546
398	Phosphorylation	STSGARSSSTIRIKT CCCCCCCCCEEEEEE	26.41	21712546
399	Phosphorylation	TSGARSSSTIRIKTF CCCCCCCCEEEEEEH	29.15	21712546
400	Phosphorylation	SGARSSSTIRIKTFS CCCCCCCEEEEEEHH	19.07	-
404	Sumoylation	SSSTIRIKTFSEVLA CCCEEEEEEHHHHHH	33.40	-
404	Sumoylation	SSSTIRIKTFSEVLA CCCEEEEEEHHHHHH	33.40	-
404	Ubiquitination	SSSTIRIKTFSEVLA CCCEEEEEEHHHHHH	33.40	32142685
407	Phosphorylation	TIRIKTFSEVLAEKK EEEEEEHHHHHHHHH	31.84	21815630
413	Acetylation	FSEVLAEKKHRQQEA HHHHHHHHHHHHHHH	48.55	23236377
413	Ubiquitination	FSEVLAEKKHRQQEA HHHHHHHHHHHHHHH	48.55	29967540
414	Ubiquitination	SEVLAEKKHRQQEAE HHHHHHHHHHHHHHH	35.21	-
425	Phosphorylation	QEAERQKSKKDTTCI HHHHHHHCCCCCEEE	36.28	30387612
429	Phosphorylation	RQKSKKDTTCIKLKI HHHCCCCCEEEEEEE	32.23	29083192
430	Phosphorylation	QKSKKDTTCIKLKID HHCCCCCEEEEEEEC	23.51	29083192
433	Acetylation	KKDTTCIKLKIDSEI CCCCEEEEEEECCCC	45.96	25953088
435	Ubiquitination	DTTCIKLKIDSEIKK CCEEEEEEECCCCCE	39.19	29967540
442	Ubiquitination	KIDSEIKKTVVLPPI EECCCCCEEEECCCE	52.81	-
443	Phosphorylation	IDSEIKKTVVLPPIV ECCCCCEEEECCCEE	15.73	28555341
452	Phosphorylation	VLPPIVASRGQSEEP ECCCEECCCCCCCCC	26.50	25159151
456	Phosphorylation	IVASRGQSEEPAGKT EECCCCCCCCCCCCC	46.91	28985074
462	Ubiquitination	QSEEPAGKTKSMQEV CCCCCCCCCCCCEEE	55.69	29967540
462	Acetylation	QSEEPAGKTKSMQEV CCCCCCCCCCCCEEE	55.69	25953088
464	Ubiquitination	EEPAGKTKSMQEVHI CCCCCCCCCCEEEEE	47.63	29967540
465	Phosphorylation	EPAGKTKSMQEVHIK CCCCCCCCCEEEEEE	30.81	25159151
478	Sumoylation	IKTLEEIKLEKALRV EEEHHHHHHHHHHHH	54.60	-
478	Sumoylation	IKTLEEIKLEKALRV EEEHHHHHHHHHHHH	54.60	28112733
478	Ubiquitination	IKTLEEIKLEKALRV EEEHHHHHHHHHHHH	54.60	29967540
478	Acetylation	IKTLEEIKLEKALRV EEEHHHHHHHHHHHH	54.60	26051181
481	Ubiquitination	LEEIKLEKALRVQQS HHHHHHHHHHHHHCC	64.26	-
488	Phosphorylation	KALRVQQSSESSTSS HHHHHHCCCCCCCCC	20.98	27461979
489	Phosphorylation	ALRVQQSSESSTSSP HHHHHCCCCCCCCCC	36.84	27461979
491	Phosphorylation	RVQQSSESSTSSPSQ HHHCCCCCCCCCCCH	40.64	21955146
492	Phosphorylation	VQQSSESSTSSPSQH HHCCCCCCCCCCCHH	28.40	21955146
493	Phosphorylation	QQSSESSTSSPSQHE HCCCCCCCCCCCHHC	42.37	21955146
494	Phosphorylation	QSSESSTSSPSQHEA CCCCCCCCCCCHHCC	42.05	23401153
495	Phosphorylation	SSESSTSSPSQHEAT CCCCCCCCCCHHCCC	28.76	25159151
497	Phosphorylation	ESSTSSPSQHEATPG CCCCCCCCHHCCCHH	46.23	21955146
502	Phosphorylation	SPSQHEATPGARRLL CCCHHCCCHHHHHHH	21.19	25159151
512	Phosphorylation	ARRLLRITKRTGMKE HHHHHHHHHHHCCCC	14.19	20068231
515	Phosphorylation	LLRITKRTGMKEEKN HHHHHHHHCCCCCCC	43.09	20068231
518	Acetylation	ITKRTGMKEEKNLQE HHHHHCCCCCCCCCC	65.16	26051181
521	Ubiquitination	RTGMKEEKNLQEGNE HHCCCCCCCCCCCCC	65.14	24816145
531	Phosphorylation	QEGNEVDSQSSIRTE CCCCCCCCHHHHHHH	36.82	21815630
533	Phosphorylation	GNEVDSQSSIRTEAK CCCCCCHHHHHHHHH	31.52	27732954
534	Phosphorylation	NEVDSQSSIRTEAKE CCCCCHHHHHHHHHH	14.41	27732954
540	Ubiquitination	SSIRTEAKEASGETT HHHHHHHHHHCCCCC	47.80	-
543	Phosphorylation	RTEAKEASGETTGVD HHHHHHHCCCCCCCC	37.95	22210691
546	Phosphorylation	AKEASGETTGVDITK HHHHCCCCCCCCCEE	32.16	30576142
547	Phosphorylation	KEASGETTGVDITKI HHHCCCCCCCCCEEE	30.79	22210691
552	Phosphorylation	ETTGVDITKIQVKRC CCCCCCCEEEEEEEH	20.03	22210691
553	Ubiquitination	TTGVDITKIQVKRCE CCCCCCEEEEEEEHH	31.32	29967540
553	Acetylation	TTGVDITKIQVKRCE CCCCCCEEEEEEEHH	31.32	26051181
561	Phosphorylation	IQVKRCETMREKHMQ EEEEEHHHHHHHHHH	25.75	-
575	Ubiquitination	QKQQEREKSVLTPLR HHHHHHHHHCCHHCC	52.68	29967540
575	Acetylation	QKQQEREKSVLTPLR HHHHHHHHHCCHHCC	52.68	25953088
576	Phosphorylation	KQQEREKSVLTPLRG HHHHHHHHCCHHCCC	20.01	30576142
579	Phosphorylation	EREKSVLTPLRGDVA HHHHHCCHHCCCCHH	20.37	25159151
587	Phosphorylation	PLRGDVASCNTQVAE HCCCCHHHCCCHHCC	14.03	26074081
590	Phosphorylation	GDVASCNTQVAEKPV CCHHHCCCHHCCCCH	28.84	30576142
595	Acetylation	CNTQVAEKPVLTAVP CCCHHCCCCHHHCCC	30.59	23954790
595	Ubiquitination	CNTQVAEKPVLTAVP CCCHHCCCCHHHCCC	30.59	29967540
599	Phosphorylation	VAEKPVLTAVPGITR HCCCCHHHCCCCHHH	26.33	22199227
605	Phosphorylation	LTAVPGITRHLTKRL HHCCCCHHHHHHHCC	20.25	22199227
609	Phosphorylation	PGITRHLTKRLPTKS CCHHHHHHHCCCCCC	14.16	-
615	Ubiquitination	LTKRLPTKSSQKVEV HHHCCCCCCCCCEEE	46.28	29967540
616	Phosphorylation	TKRLPTKSSQKVEVE HHCCCCCCCCCEEEE	40.24	21130716
619	Sumoylation	LPTKSSQKVEVETSG CCCCCCCCEEEEECC	42.16	-
619	Sumoylation	LPTKSSQKVEVETSG CCCCCCCCEEEEECC	42.16	28112733
619	Ubiquitination	LPTKSSQKVEVETSG CCCCCCCCEEEEECC	42.16	29967540
619	Acetylation	LPTKSSQKVEVETSG CCCCCCCCEEEEECC	42.16	25953088
624	Phosphorylation	SQKVEVETSGIGDSL CCCEEEEECCCCHHH	37.11	27251275
625	Phosphorylation	QKVEVETSGIGDSLL CCEEEEECCCCHHHH	18.20	25159151
630	Phosphorylation	ETSGIGDSLLNVKCA EECCCCHHHHHHHHH	29.55	27251275
635	Ubiquitination	GDSLLNVKCAAQTLE CHHHHHHHHHHHHHH	19.65	32015554
643	Acetylation	CAAQTLEKRGKAKPK HHHHHHHHCCCCCCC	70.35	25953088
654	Ubiquitination	AKPKVNVKPSVVKVV CCCCCCCCCCEEEEE	26.77	29967540
654	Acetylation	AKPKVNVKPSVVKVV CCCCCCCCCCEEEEE	26.77	25953088
656	Phosphorylation	PKVNVKPSVVKVVSS CCCCCCCCEEEEECC	33.55	28555341
659	Ubiquitination	NVKPSVVKVVSSPKL CCCCCEEEEECCCCC	34.46	29967540
659	Acetylation	NVKPSVVKVVSSPKL CCCCCEEEEECCCCC	34.46	25953088
662	Phosphorylation	PSVVKVVSSPKLAPK CCEEEEECCCCCCCC	43.86	24732914
663	Phosphorylation	SVVKVVSSPKLAPKR CEEEEECCCCCCCCC	17.91	24732914
665	Acetylation	VKVVSSPKLAPKRKA EEEECCCCCCCCCHH	60.26	23749302
665	Ubiquitination	VKVVSSPKLAPKRKA EEEECCCCCCCCCHH	60.26	29967540
684	Acetylation	AAVIAAVKPLSSSSV HHHHHHHCCCCCCHH	35.20	23749302
687	Phosphorylation	IAAVKPLSSSSVLQE HHHHCCCCCCHHHCC	36.38	25159151
688	Phosphorylation	AAVKPLSSSSVLQEP HHHCCCCCCHHHCCC	34.02	25159151
689	Phosphorylation	AVKPLSSSSVLQEPP HHCCCCCCHHHCCCC	22.53	-
690	Phosphorylation	VKPLSSSSVLQEPPA HCCCCCCHHHCCCCC	28.88	-
698	Acetylation	VLQEPPAKKAAVAVV HHCCCCCCCCEEEEE	49.03	26051181
699	Ubiquitination	LQEPPAKKAAVAVVP HCCCCCCCCEEEEEE	43.62	29967540
709	Phosphorylation	VAVVPLVSEDKSVTV EEEEECCCCCCCCCC	48.00	20860994
712	Ubiquitination	VPLVSEDKSVTVPEA EECCCCCCCCCCCCC	42.65	29967540
713	Phosphorylation	PLVSEDKSVTVPEAE ECCCCCCCCCCCCCC	35.03	26074081
715	Phosphorylation	VSEDKSVTVPEAENP CCCCCCCCCCCCCCC	37.12	26074081
725	Phosphorylation	EAENPRDSLVLPPTQ CCCCCCCCCCCCCCC	22.96	20873877
731	Phosphorylation	DSLVLPPTQSSSDSS CCCCCCCCCCCCCCC	38.86	30278072
733	Phosphorylation	LVLPPTQSSSDSSPP CCCCCCCCCCCCCCC	34.00	30278072
734	Phosphorylation	VLPPTQSSSDSSPPE CCCCCCCCCCCCCCC	28.48	30278072
735	Phosphorylation	LPPTQSSSDSSPPEV CCCCCCCCCCCCCCC	46.92	30278072
737	Phosphorylation	PTQSSSDSSPPEVSG CCCCCCCCCCCCCCC	46.85	30278072
738	Phosphorylation	TQSSSDSSPPEVSGP CCCCCCCCCCCCCCC	49.84	30278072
743	Phosphorylation	DSSPPEVSGPSSSQM CCCCCCCCCCCHHHH	43.24	25262027
746	Phosphorylation	PPEVSGPSSSQMSMK CCCCCCCCHHHHCCC	46.26	25262027
747	Phosphorylation	PEVSGPSSSQMSMKT CCCCCCCHHHHCCCE	27.94	20873877
748	Phosphorylation	EVSGPSSSQMSMKTR CCCCCCHHHHCCCEE	33.95	20873877
751	Phosphorylation	GPSSSQMSMKTRRLS CCCHHHHCCCEECCC	14.97	20873877
754	Phosphorylation	SSQMSMKTRRLSSAS HHHHCCCEECCCCCC	16.63	30576142
757	Phosphorylation	MSMKTRRLSSASTGK HCCCEECCCCCCCCC	4.23	32142685
758	Phosphorylation	SMKTRRLSSASTGKP CCCEECCCCCCCCCC	23.26	29255136
759	Phosphorylation	MKTRRLSSASTGKPP CCEECCCCCCCCCCC	30.72	29255136
761	Phosphorylation	TRRLSSASTGKPPLS EECCCCCCCCCCCCC	39.37	29255136
762	Phosphorylation	RRLSSASTGKPPLSV ECCCCCCCCCCCCCC	49.28	29255136
764	Acetylation	LSSASTGKPPLSVED CCCCCCCCCCCCCHH	43.48	23954790
764	Ubiquitination	LSSASTGKPPLSVED CCCCCCCCCCCCCHH	43.48	19608861
768	Phosphorylation	STGKPPLSVEDDFEK CCCCCCCCCHHHHHH	29.27	29255136
781	Phosphorylation	EKLIWEISGGKLEAE HHHHHHHHCCEEEEE	29.94	21815630

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
321	T	Phosphorylation	Kinase	CDK1	P06493	PSP
321	T	Phosphorylation	Kinase	CDK2	P24941	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZC11A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZC11A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ZC11A_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZC11A_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-764, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108 AND SER-738, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108 AND SER-132, ANDMASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108; SER-132; SER-171;SER-290; THR-321; SER-758; SER-759 AND SER-768, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-132, AND MASSSPECTROMETRY.	18220336 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-132; SER-149 ANDSER-171, AND MASS SPECTROMETRY.	19007248 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108 AND SER-116, ANDMASS SPECTROMETRY.	17525332 [Abstract]
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry."; Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.; Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-758; SER-759; SER-761AND THR-762, AND MASS SPECTROMETRY.	17287340 [Abstract]
"Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108; SER-132 ANDSER-495, AND MASS SPECTROMETRY.	16565220 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108 AND SER-132, ANDMASS SPECTROMETRY.	16964243 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-290 AND SER-758, ANDMASS SPECTROMETRY.	17081983 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-132, AND MASSSPECTROMETRY.	15302935 [Abstract]