dbPTM

IF4G1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	IF4G1_HUMAN
UniProt AC	Q04637
Protein Name	Eukaryotic translation initiation factor 4 gamma 1
Gene Name	EIF4G1
Organism	Homo sapiens (Human).
Sequence Length	1599
Subcellular Localization
Protein Description	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome..
Protein Sequence	MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPTPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2 (in isoform 4)	Acetylation	-	61.57	22814378
6 (in isoform 6)	Phosphorylation	-	59.49	19651622
6 (in isoform 7)	Phosphorylation	-	59.49	19651622
8 (in isoform 6)	Phosphorylation	-	48.76	25159151
8 (in isoform 7)	Phosphorylation	-	48.76	25159151
9 (in isoform 6)	Phosphorylation	-	37.65	25159151
9 (in isoform 7)	Phosphorylation	-	37.65	25159151
11 (in isoform 6)	Phosphorylation	-	38.74	25159151
11 (in isoform 7)	Phosphorylation	-	38.74	25159151
15	Phosphorylation	TGPPPAPSPGLPQPA CCCCCCCCCCCCCCC	33.43	28348404
43	Phosphorylation	PQATQMNTPSQPRQH CCCCCCCCCCCCCCC	20.97	25850435
45	Phosphorylation	ATQMNTPSQPRQHFY CCCCCCCCCCCCCCC	51.26	25850435
48	Dimethylation	MNTPSQPRQHFYPSR CCCCCCCCCCCCCCC	34.66	-
48	Methylation	MNTPSQPRQHFYPSR CCCCCCCCCCCCCCC	34.66	-
52	Phosphorylation	SQPRQHFYPSRAQPP CCCCCCCCCCCCCCC	9.73	-
54	Phosphorylation	PRQHFYPSRAQPPSS CCCCCCCCCCCCCCH	28.95	20068231
55	Dimethylation	RQHFYPSRAQPPSSA CCCCCCCCCCCCCHH	32.51	-
55	Methylation	RQHFYPSRAQPPSSA CCCCCCCCCCCCCHH	32.51	-
60	O-linked_Glycosylation	PSRAQPPSSAASRVQ CCCCCCCCHHHHHHH	39.01	32574038
60	Phosphorylation	PSRAQPPSSAASRVQ CCCCCCCCHHHHHHH	39.01	23312004
61	O-linked_Glycosylation	SRAQPPSSAASRVQS CCCCCCCHHHHHHHH	33.36	32574038
61	O-linked_Glycosylation	SRAQPPSSAASRVQS CCCCCCCHHHHHHHH	33.36	20068230
61	Phosphorylation	SRAQPPSSAASRVQS CCCCCCCHHHHHHHH	33.36	23312004
64	O-linked_Glycosylation	QPPSSAASRVQSAAP CCCCHHHHHHHHCCC	32.47	32574038
64	Phosphorylation	QPPSSAASRVQSAAP CCCCHHHHHHHHCCC	32.47	23312004
65	Methylation	PPSSAASRVQSAAPA CCCHHHHHHHHCCCC	26.26	-
73	Dimethylation	VQSAAPARPGPAAHV HHHCCCCCCCCCCEE	35.33	-
73	Methylation	VQSAAPARPGPAAHV HHHCCCCCCCCCCEE	35.33	24129315
85	Phosphorylation	AHVYPAGSQVMMIPS CEEECCCCEEEEEEC	23.00	28555341
103	Phosphorylation	YPASQGAYYIPGQGR CCHHHCCEECCCCCC	14.57	23917254
110	Methylation	YYIPGQGRSTYVVPT EECCCCCCCEEEEEC	20.24	24129315
130	Phosphorylation	QPGAPGFYPGASPTE CCCCCCCCCCCCCCC	13.48	26074081
134	Phosphorylation	PGFYPGASPTEFGTY CCCCCCCCCCCCCCC	37.97	26074081
136	Phosphorylation	FYPGASPTEFGTYAG CCCCCCCCCCCCCCC	41.26	18669648
179	Phosphorylation	APKRERKTIRIRDPN CCCCCCCCEEECCCC	23.00	26074081
190	Acetylation	RDPNQGGKDITEEIM CCCCCCCCCCHHHHH	53.43	66728965
193	Phosphorylation	NQGGKDITEEIMSGA CCCCCCCHHHHHHCC	37.39	28555341
197	Sulfoxidation	KDITEEIMSGARTAS CCCHHHHHHCCCCCC	3.23	21406390
198	O-linked_Glycosylation	DITEEIMSGARTAST CCHHHHHHCCCCCCC	34.66	32574038
198	Phosphorylation	DITEEIMSGARTAST CCHHHHHHCCCCCCC	34.66	25022875
202	Phosphorylation	EIMSGARTASTPTPP HHHHCCCCCCCCCCC	25.15	23401153
204	Phosphorylation	MSGARTASTPTPPQT HHCCCCCCCCCCCCC	34.02	25159151
205	Phosphorylation	SGARTASTPTPPQTG HCCCCCCCCCCCCCC	28.81	25159151
207	Phosphorylation	ARTASTPTPPQTGGG CCCCCCCCCCCCCCC	47.92	25159151
211	Phosphorylation	STPTPPQTGGGLEPQ CCCCCCCCCCCCCCC	43.50	30266825
223	Phosphorylation	EPQANGETPQVAVIV CCCCCCCCCCEEEEE	22.03	30266825
236	Phosphorylation	IVRPDDRSQGAIIAD EECCCCCCCCEEEEC	39.70	28464451
253	Phosphorylation	GLPGPEHSPSESQPS CCCCCCCCCCCCCCC	28.58	20068231
255	Phosphorylation	PGPEHSPSESQPSSP CCCCCCCCCCCCCCC	53.55	20068231
257	Phosphorylation	PEHSPSESQPSSPSP CCCCCCCCCCCCCCC	52.29	26074081
260	Phosphorylation	SPSESQPSSPSPTPS CCCCCCCCCCCCCCC	47.44	26074081
261	Phosphorylation	PSESQPSSPSPTPSP CCCCCCCCCCCCCCC	35.76	26074081
263	Phosphorylation	ESQPSSPSPTPSPSP CCCCCCCCCCCCCCC	43.27	26074081
265	Phosphorylation	QPSSPSPTPSPSPVL CCCCCCCCCCCCCCC	40.51	26074081
267	Phosphorylation	SSPSPTPSPSPVLEP CCCCCCCCCCCCCCC	40.25	26074081
269	Phosphorylation	PSPTPSPSPVLEPGS CCCCCCCCCCCCCCC	31.79	26074081
276	Phosphorylation	SPVLEPGSEPNLAVL CCCCCCCCCCCEEEE	61.67	20068231
284	Phosphorylation	EPNLAVLSIPGDTMT CCCEEEEECCCCCEE	21.82	20068231
289	Phosphorylation	VLSIPGDTMTTIQMS EEECCCCCEEEEEEE	23.49	20068231
291	Phosphorylation	SIPGDTMTTIQMSVE ECCCCCEEEEEEEEE	23.88	20068231
292	O-linked_Glycosylation	IPGDTMTTIQMSVEE CCCCCEEEEEEEEEC	9.82	OGP
292	Phosphorylation	IPGDTMTTIQMSVEE CCCCCEEEEEEEEEC	9.82	20068231
296	Phosphorylation	TMTTIQMSVEESTPI CEEEEEEEEECCCCC	15.25	20068231
300	Phosphorylation	IQMSVEESTPISRET EEEEEECCCCCCCCC	26.44	20068231
301	Phosphorylation	QMSVEESTPISRETG EEEEECCCCCCCCCC	28.11	20068231
304	Phosphorylation	VEESTPISRETGEPY EECCCCCCCCCCCCC	25.85	20068231
307	Phosphorylation	STPISRETGEPYRLS CCCCCCCCCCCCCCC	45.81	22167270
311	Phosphorylation	SRETGEPYRLSPEPT CCCCCCCCCCCCCCC	21.63	22167270
314	Phosphorylation	TGEPYRLSPEPTPLA CCCCCCCCCCCCCCC	20.44	19664994
318	Phosphorylation	YRLSPEPTPLAEPIL CCCCCCCCCCCCCEE	29.31	22167270
330	Phosphorylation	PILEVEVTLSKPVPE CEEEEEEEECCCCCH	16.29	23090842
332	Phosphorylation	LEVEVTLSKPVPESE EEEEEEECCCCCHHH	26.08	20873877
338	Phosphorylation	LSKPVPESEFSSSPL ECCCCCHHHCCCCCC	37.56	26074081
341	Phosphorylation	PVPESEFSSSPLQAP CCCHHHCCCCCCCCC	26.34	26074081
342	Phosphorylation	VPESEFSSSPLQAPT CCHHHCCCCCCCCCC	41.10	26074081
343	Phosphorylation	PESEFSSSPLQAPTP CHHHCCCCCCCCCCC	28.56	26074081
349	Phosphorylation	SSPLQAPTPLASHTV CCCCCCCCCCCCCEE	33.67	26074081
353	Phosphorylation	QAPTPLASHTVEIHE CCCCCCCCCEEEEEC	27.63	26074081
355	Phosphorylation	PTPLASHTVEIHEPN CCCCCCCEEEEECCC	19.83	26074081
409	Phosphorylation	ELLNGAPSPPAVDLS HHHCCCCCCCCCCCC	42.87	26074081
416	Phosphorylation	SPPAVDLSPVSEPEE CCCCCCCCCCCCHHH	20.84	26074081
416 (in isoform 6)	Ubiquitination	-	20.84	21890473
419	Phosphorylation	AVDLSPVSEPEEQAK CCCCCCCCCHHHHHH	51.31	26074081
429 (in isoform 6)	Ubiquitination	-	17.69	21890473
433 (in isoform 6)	Ubiquitination	-	12.39	21890473
438 (in isoform 6)	Ubiquitination	-	22.01	21890473
439	Phosphorylation	MAPPTIPSATPATAP CCCCCCCCCCCCCCC	40.71	28348404
441	Phosphorylation	PPTIPSATPATAPSA CCCCCCCCCCCCCCC	20.14	28348404
444	Phosphorylation	IPSATPATAPSATSP CCCCCCCCCCCCCCH	40.06	28348404
447	Phosphorylation	ATPATAPSATSPAQE CCCCCCCCCCCHHHH	41.54	30576142
449	Phosphorylation	PATAPSATSPAQEEE CCCCCCCCCHHHHHH	39.31	30576142
450	Phosphorylation	ATAPSATSPAQEEEM CCCCCCCCHHHHHHH	20.25	30576142
488	Phosphorylation	EELLPPESTPIPANL CCCCCCCCCCCCCCC	45.30	27251275
489	Phosphorylation	ELLPPESTPIPANLS CCCCCCCCCCCCCCC	24.47	27251275
489 (in isoform 7)	Methylation	-	24.47	24129315
493 (in isoform 5)	Ubiquitination	-	30.25	21890473
496	Phosphorylation	TPIPANLSQNLEAAA CCCCCCCCHHHHHHH	19.48	28348404
498 (in isoform 7)	Methylation	-	36.15	24129315
506 (in isoform 5)	Ubiquitination	-	19.22	21890473
509 (in isoform 7)	Phosphorylation	-	6.61	23403867
510 (in isoform 5)	Ubiquitination	-	23.98	21890473
515 (in isoform 5)	Ubiquitination	-	50.82	21890473
519	Sumoylation	PKRRRKIKELNKKEA HHHHHHHHHHCHHHH	60.22	-
524	Ubiquitination	KIKELNKKEAVGDLL HHHHHCHHHHHHHHH	50.24	-
540 (in isoform 4)	Ubiquitination	-	29.33	21890473
553 (in isoform 3)	Ubiquitination	-	44.63	-
553 (in isoform 4)	Ubiquitination	-	44.63	21890473
557 (in isoform 4)	Ubiquitination	-	68.30	21890473
562 (in isoform 4)	Ubiquitination	-	46.97	21890473
580	Ubiquitination	TWDSKEDKIHNAENI CCCCCCHHCCCCCCC	47.13	21890473
580 (in isoform 1)	Ubiquitination	-	47.13	21890473
580 (in isoform 3)	Ubiquitination	-	47.13	21890473
593	Acetylation	NIQPGEQKYEYKSDQ CCCCCCCEEEECCCC	35.43	23236377
593	Ubiquitination	NIQPGEQKYEYKSDQ CCCCCCCEEEECCCC	35.43	21890473
593 (in isoform 1)	Ubiquitination	-	35.43	21890473
593 (in isoform 3)	Ubiquitination	-	35.43	21890473
594	Phosphorylation	IQPGEQKYEYKSDQW CCCCCCEEEECCCCC	24.96	21945579
596	Phosphorylation	PGEQKYEYKSDQWKP CCCCEEEECCCCCCC	16.83	21945579
597	Ubiquitination	GEQKYEYKSDQWKPL CCCEEEECCCCCCCC	35.30	21890473
597 (in isoform 1)	Ubiquitination	-	35.30	21890473
597 (in isoform 3)	Ubiquitination	-	35.30	21890473
598	Phosphorylation	EQKYEYKSDQWKPLN CCEEEECCCCCCCCC	33.85	25159151
602	Acetylation	EYKSDQWKPLNLEEK EECCCCCCCCCHHHH	33.71	25953088
602	Ubiquitination	EYKSDQWKPLNLEEK EECCCCCCCCCHHHH	33.71	21890473
602 (in isoform 3)	Ubiquitination	-	33.71	21890473
607 (in isoform 6)	Ubiquitination	-	67.70	21890473
609	Ubiquitination	KPLNLEEKKRYDREF CCCCHHHHHHCCHHH	32.92	-
632 (in isoform 6)	Ubiquitination	-	53.70	21890473
637	Phosphorylation	PEGLPHISDVVLDKA CCCCCCHHHHHHCCC	22.71	21815630
646	Ubiquitination	VVLDKANKTPLRPLD HHHCCCCCCCCCCCC	57.27	-
647	Phosphorylation	VLDKANKTPLRPLDP HHCCCCCCCCCCCCH	27.62	25159151
655	Phosphorylation	PLRPLDPTRLQGINC CCCCCCHHHCCCCCC	43.61	22199227
662	Glutathionylation	TRLQGINCGPDFTPS HHCCCCCCCCCCCHH	8.71	22555962
667	Phosphorylation	INCGPDFTPSFANLG CCCCCCCCHHHHHCC	25.96	21815630
669	Phosphorylation	CGPDFTPSFANLGRT CCCCCCHHHHHCCCC	33.65	25850435
669 (in isoform 6)	Ubiquitination	-	33.65	21890473
675	Methylation	PSFANLGRTTLSTRG HHHHHCCCCCCCCCC	27.92	-
676	Phosphorylation	SFANLGRTTLSTRGP HHHHCCCCCCCCCCC	30.23	26434776
677	Phosphorylation	FANLGRTTLSTRGPP HHHCCCCCCCCCCCC	19.83	24719451
679	Phosphorylation	NLGRTTLSTRGPPRG HCCCCCCCCCCCCCC	17.61	26434776
680	Phosphorylation	LGRTTLSTRGPPRGG CCCCCCCCCCCCCCC	42.64	26434776
681	Methylation	GRTTLSTRGPPRGGP CCCCCCCCCCCCCCC	52.85	-
684 (in isoform 5)	Ubiquitination	-	50.82	21890473
685	Methylation	LSTRGPPRGGPGGEL CCCCCCCCCCCCCCC	66.87	24129315
685 (in isoform 8)	Methylation	-	66.87	24129315
694	Methylation	GPGGELPRGPAGLGP CCCCCCCCCCCCCCC	76.09	24129315
694 (in isoform 8)	Methylation	-	76.09	24129315
700 (in isoform 6)	Ubiquitination	-	16.86	21890473
702	Methylation	GPAGLGPRRSQQGPR CCCCCCCCCCCCCCC	49.43	-
703 (in isoform 8)	Methylation	-	41.78	-
704	Phosphorylation	AGLGPRRSQQGPRKE CCCCCCCCCCCCCCC	28.30	28176443
705	Phosphorylation	GLGPRRSQQGPRKEP CCCCCCCCCCCCCCC	50.90	27251275
705 (in isoform 8)	Phosphorylation	-	50.90	23403867
709 (in isoform 5)	Ubiquitination	-	63.89	21890473
718	Phosphorylation	EPRKIIATVLMTEDI CCCHHHEEEEECCCC	12.08	23403867
721	Sulfoxidation	KIIATVLMTEDIKLN HHHEEEEECCCCCCC	3.16	21406390
722	Phosphorylation	IIATVLMTEDIKLNK HHEEEEECCCCCCCH	26.75	23403867
730 (in isoform 4)	Ubiquitination	-	23.58	21890473
732	Ubiquitination	IKLNKAEKAWKPSSK CCCCHHHHCCCCCCC	65.49	-
735	Ubiquitination	NKAEKAWKPSSKRTA CHHHHCCCCCCCCCC	39.62	-
737 (in isoform 6)	Ubiquitination	-	44.77	21890473
739	Acetylation	KAWKPSSKRTAADKD HCCCCCCCCCCCCCC	59.09	25953088
744 (in isoform 6)	Ubiquitination	-	51.42	21890473
746 (in isoform 5)	Ubiquitination	-	65.45	21890473
755	Acetylation	GEEDADGSKTQDLFR CCCCCCCCHHHHHHH	32.83	19608861
755	Phosphorylation	GEEDADGSKTQDLFR CCCCCCCCHHHHHHH	32.83	25367160
755 (in isoform 4)	Ubiquitination	-	32.83	21890473
756	Ubiquitination	EEDADGSKTQDLFRR CCCCCCCHHHHHHHH	56.59	-
766	Phosphorylation	DLFRRVRSILNKLTP HHHHHHHHHHHHHCH	28.68	24719451
770	Ubiquitination	RVRSILNKLTPQMFQ HHHHHHHHHCHHHHH	50.74	21890473
771 (in isoform 1)	Ubiquitination	-	9.10	21890473
771 (in isoform 3)	Ubiquitination	-	9.10	21890473
777 (in isoform 5)	Ubiquitination	-	30.10	21890473
781	Ubiquitination	QMFQQLMKQVTQLAI HHHHHHHHHHHHHHC	50.65	-
786	Acetylation	LMKQVTQLAIDTEER HHHHHHHHHCCHHHH	3.09	19608861
792 (in isoform 4)	Ubiquitination	-	66.46	21890473
795	Ubiquitination	IDTEERLKGVIDLIF CCHHHHHHHHHHHHH	58.30	21890473
796 (in isoform 1)	Ubiquitination	-	26.63	21890473
796 (in isoform 3)	Ubiquitination	-	26.63	21890473
814 (in isoform 5)	Ubiquitination	-	9.12	21890473
821 (in isoform 5)	Ubiquitination	-	2.31	21890473
823 (in isoform 4)	Ubiquitination	-	4.74	21890473
826	Acetylation	CRCLMALKVPTTEKP HHHHHCCCCCCCCCC	36.31	26051181
826	Malonylation	CRCLMALKVPTTEKP HHHHHCCCCCCCCCC	36.31	26320211
832	Acetylation	LKVPTTEKPTVTVNF CCCCCCCCCEEEEEH	43.85	25953088
832	Malonylation	LKVPTTEKPTVTVNF CCCCCCCCCEEEEEH	43.85	26320211
832	Ubiquitination	LKVPTTEKPTVTVNF CCCCCCCCCEEEEEH	43.85	-
833 (in isoform 1)	Ubiquitination	-	26.35	21890473
833 (in isoform 3)	Ubiquitination	-	26.35	21890473
834	Phosphorylation	VPTTEKPTVTVNFRK CCCCCCCEEEEEHHH	39.62	23898821
836	Phosphorylation	TTEKPTVTVNFRKLL CCCCCEEEEEHHHHH	16.53	23898821
860 (in isoform 3)	Ubiquitination	-	10.91	-
860 (in isoform 4)	Ubiquitination	-	10.91	21890473
863	Acetylation	DDDEVFEKKQKEMDE CHHHHHHHHHHHHHH	49.38	-
863	Ubiquitination	DDDEVFEKKQKEMDE CHHHHHHHHHHHHHH	49.38	21906983
864 (in isoform 1)	Ubiquitination	-	60.45	21890473
864 (in isoform 3)	Ubiquitination	-	60.45	21890473
867 (in isoform 4)	Ubiquitination	-	49.74	21890473
877	Methylation	EAATAEERGRLKEEL HHHHHHHHHHHHHHH	27.34	-
881	Acetylation	AEERGRLKEELEEAR HHHHHHHHHHHHHHH	48.02	26051181
881	Ubiquitination	AEERGRLKEELEEAR HHHHHHHHHHHHHHH	48.02	-
895	Phosphorylation	RDIARRRSLGNIKFI HHHHHHHCCCCCCHH	38.53	16281055
896 (in isoform 6)	Ubiquitination	-	6.05	21890473
900	Acetylation	RRSLGNIKFIGELFK HHCCCCCCHHHHHHH	34.62	19608861
900	Ubiquitination	RRSLGNIKFIGELFK HHCCCCCCHHHHHHH	34.62	21890473
901 (in isoform 1)	Ubiquitination	-	8.42	21890473
901 (in isoform 3)	Ubiquitination	-	8.42	21890473
907	Ubiquitination	KFIGELFKLKMLTEA CHHHHHHHHHHHHHH	60.88	-
908 (in isoform 1)	Ubiquitination	-	2.86	21890473
908 (in isoform 3)	Ubiquitination	-	2.86	21890473
925	Ubiquitination	DCVVKLLKNHDEESL HHHHHHHHCCCHHHH	63.77	-
931	Acetylation	LKNHDEESLECLCRL HHCCCHHHHHHHHHH	27.67	19608861
944	Ubiquitination	RLLTTIGKDLDFEKA HHHHHHCCCCCHHHH	51.79	-
950	Acetylation	GKDLDFEKAKPRMDQ CCCCCHHHHHHHHHH	62.80	19608861
950	Ubiquitination	GKDLDFEKAKPRMDQ CCCCCHHHHHHHHHH	62.80	19608861
954	Methylation	DFEKAKPRMDQYFNQ CHHHHHHHHHHHHHH	40.37	-
964	Acetylation	QYFNQMEKIIKEKKT HHHHHHHHHHHHCCC	44.37	25953088
964	Ubiquitination	QYFNQMEKIIKEKKT HHHHHHHHHHHHCCC	44.37	-
967	Ubiquitination	NQMEKIIKEKKTSSR HHHHHHHHHCCCCHH	67.94	-
973 (in isoform 5)	Ubiquitination	-	36.64	21890473
993	Acetylation	RGSNWVPRRGDQGPK CCCCCCCCCCCCCCC	45.66	19608861
1000	Acetylation	RRGDQGPKTIDQIHK CCCCCCCCHHHHHHH	66.01	26051181
1001	Phosphorylation	RGDQGPKTIDQIHKE CCCCCCCHHHHHHHH	32.68	28555341
1007	Malonylation	KTIDQIHKEAEMEEH CHHHHHHHHHHHHHH	61.32	26320211
1019	Ubiquitination	EEHREHIKVQQLMAK HHHHHHHHHHHHHHC	35.58	-
1019 (in isoform 4)	Ubiquitination	-	35.58	21890473
1024	Acetylation	HIKVQQLMAKGSDKR HHHHHHHHHCCCCCC	2.92	19608861
1026	Acetylation	KVQQLMAKGSDKRRG HHHHHHHCCCCCCCC	45.01	26051181
1026	Malonylation	KVQQLMAKGSDKRRG HHHHHHHCCCCCCCC	45.01	26320211
1026	Methylation	KVQQLMAKGSDKRRG HHHHHHHCCCCCCCC	45.01	-
1026	Ubiquitination	KVQQLMAKGSDKRRG HHHHHHHCCCCCCCC	45.01	-
1028	Phosphorylation	QQLMAKGSDKRRGGP HHHHHCCCCCCCCCC	38.97	28355574
1031	Methylation	MAKGSDKRRGGPPGP HHCCCCCCCCCCCCC	47.68	-
1032	Dimethylation	AKGSDKRRGGPPGPP HCCCCCCCCCCCCCC	61.23	-
1032	Methylation	AKGSDKRRGGPPGPP HCCCCCCCCCCCCCC	61.23	24129315
1041	O-linked_Glycosylation	GPPGPPISRGLPLVD CCCCCCCCCCCCCCC	26.52	32574038
1041	Phosphorylation	GPPGPPISRGLPLVD CCCCCCCCCCCCCCC	26.52	28555341
1042	Dimethylation	PPGPPISRGLPLVDD CCCCCCCCCCCCCCC	51.92	-
1042	Methylation	PPGPPISRGLPLVDD CCCCCCCCCCCCCCC	51.92	24129315
1054	Phosphorylation	VDDGGWNTVPISKGS CCCCCCCEEECCCCC	22.58	30576142
1058	O-linked_Glycosylation	GWNTVPISKGSRPID CCCEEECCCCCCCCC	25.54	32574038
1058	Phosphorylation	GWNTVPISKGSRPID CCCEEECCCCCCCCC	25.54	20068231
1059	Acetylation	WNTVPISKGSRPIDT CCEEECCCCCCCCCH	62.72	25953088
1059	Methylation	WNTVPISKGSRPIDT CCEEECCCCCCCCCH	62.72	-
1059	Ubiquitination	WNTVPISKGSRPIDT CCEEECCCCCCCCCH	62.72	21890473
1060 (in isoform 1)	Ubiquitination	-	23.30	21890473
1060 (in isoform 3)	Ubiquitination	-	23.30	21890473
1066	Phosphorylation	KGSRPIDTSRLTKIT CCCCCCCHHHCCCCC	19.23	28555341
1067	Phosphorylation	GSRPIDTSRLTKITK CCCCCCHHHCCCCCC	22.88	19664995
1071	Acetylation	IDTSRLTKITKPGSI CCHHHCCCCCCCCCC	53.63	26051181
1071	Ubiquitination	IDTSRLTKITKPGSI CCHHHCCCCCCCCCC	53.63	-
1073	O-linked_Glycosylation	TSRLTKITKPGSIDS HHHCCCCCCCCCCCC	32.51	32574038
1073	Phosphorylation	TSRLTKITKPGSIDS HHHCCCCCCCCCCCC	32.51	23927012
1074	Acetylation	SRLTKITKPGSIDSN HHCCCCCCCCCCCCC	51.35	26051181
1074	Malonylation	SRLTKITKPGSIDSN HHCCCCCCCCCCCCC	51.35	26320211
1074	Ubiquitination	SRLTKITKPGSIDSN HHCCCCCCCCCCCCC	51.35	-
1077	Phosphorylation	TKITKPGSIDSNNQL CCCCCCCCCCCCCCE	31.58	26846344
1078	Phosphorylation	KITKPGSIDSNNQLF CCCCCCCCCCCCCEE	9.25	18669648
1080	Phosphorylation	TKPGSIDSNNQLFAP CCCCCCCCCCCEECC	35.69	26846344
1092	Phosphorylation	FAPGGRLSWGKGSSG ECCCCCEECCCCCCC	32.21	22167270
1093	Phosphorylation	APGGRLSWGKGSSGG CCCCCEECCCCCCCC	19.67	18669648
1095	Acetylation	GGRLSWGKGSSGGSG CCCEECCCCCCCCCC	49.73	19608861
1095	Methylation	GGRLSWGKGSSGGSG CCCEECCCCCCCCCC	49.73	19608861
1097	Phosphorylation	RLSWGKGSSGGSGAK CEECCCCCCCCCCCC	29.33	29255136
1098	Phosphorylation	LSWGKGSSGGSGAKP EECCCCCCCCCCCCH	56.70	29255136
1101	Phosphorylation	GKGSSGGSGAKPSDA CCCCCCCCCCCHHHH	38.82	19664995
1104	Acetylation	SSGGSGAKPSDAASE CCCCCCCCHHHHHHH	48.88	26051181
1104	Methylation	SSGGSGAKPSDAASE CCCCCCCCHHHHHHH	48.88	-
1106	Phosphorylation	GGSGAKPSDAASEAA CCCCCCHHHHHHHHH	38.89	23927012
1110	Phosphorylation	AKPSDAASEAARPAT CCHHHHHHHHHCCCC	29.50	23927012
1117	Phosphorylation	SEAARPATSTLNRFS HHHHCCCCHHHHHHH	25.56	22496350
1118	O-linked_Glycosylation	EAARPATSTLNRFSA HHHCCCCHHHHHHHH	32.76	32574038
1118	Phosphorylation	EAARPATSTLNRFSA HHHCCCCHHHHHHHH	32.76	23927012
1119	O-linked_Glycosylation	AARPATSTLNRFSAL HHCCCCHHHHHHHHH	24.57	32574038
1119	Phosphorylation	AARPATSTLNRFSAL HHCCCCHHHHHHHHH	24.57	30576142
1124	Phosphorylation	TSTLNRFSALQQAVP CHHHHHHHHHHHHCC	25.49	26074081
1132	Phosphorylation	ALQQAVPTESTDNRR HHHHHCCCCCCCCCH	35.65	26074081
1134	Phosphorylation	QQAVPTESTDNRRVV HHHCCCCCCCCCHHH	43.47	26074081
1135	Phosphorylation	QAVPTESTDNRRVVQ HHCCCCCCCCCHHHC	30.94	26074081
1138	Methylation	PTESTDNRRVVQRSS CCCCCCCCHHHCHHH	35.26	-
1144	Phosphorylation	NRRVVQRSSLSRERG CCHHHCHHHHHHHHH	20.66	19664994
1145	Phosphorylation	RRVVQRSSLSRERGE CHHHCHHHHHHHHHH	32.33	28355574
1146	Phosphorylation	RVVQRSSLSRERGEK HHHCHHHHHHHHHHH	6.20	16083285
1147	Phosphorylation	VVQRSSLSRERGEKA HHCHHHHHHHHHHHH	33.76	19934253
1148	Phosphorylation	VQRSSLSRERGEKAG HCHHHHHHHHHHHHC	42.81	10654941
1148 (in isoform 8)	Phosphorylation	-	42.81	-
1164	Phosphorylation	RGDRLERSERGGDRG HHHHHHHHHCCCCHH	23.44	26074081
1166	Methylation	DRLERSERGGDRGDR HHHHHHHCCCCHHHH	56.49	-
1179	Phosphorylation	DRLDRARTPATKRSF HHHHHCCCHHHHHHH	19.11	23403867
1182	Phosphorylation	DRARTPATKRSFSKE HHCCCHHHHHHHHHH	28.35	23403867
1185	Phosphorylation	RTPATKRSFSKEVEE CCHHHHHHHHHHHHH	35.11	23927012
1186	Phosphorylation	TPATKRSFSKEVEER CHHHHHHHHHHHHHH	16.36	18669648
1186 (in isoform 8)	Phosphorylation	-	16.36	-
1187	Phosphorylation	PATKRSFSKEVEERS HHHHHHHHHHHHHHH	29.20	29255136
1188	Acetylation	ATKRSFSKEVEERSR HHHHHHHHHHHHHHH	64.86	19608861
1188	Phosphorylation	ATKRSFSKEVEERSR HHHHHHHHHHHHHHH	64.86	18669648
1188	Ubiquitination	ATKRSFSKEVEERSR HHHHHHHHHHHHHHH	64.86	19608861
1194	Phosphorylation	SKEVEERSRERPSQP HHHHHHHHHHCCCCC	41.60	29255136
1199	Phosphorylation	ERSRERPSQPEGLRK HHHHHCCCCCHHHHH	65.67	22167270
1209	Phosphorylation	EGLRKAASLTEDRDR HHHHHHHHHCCCHHH	40.46	29255136
1210	Phosphorylation	GLRKAASLTEDRDRG HHHHHHHHCCCHHHC	5.36	18669648
1211	Phosphorylation	LRKAASLTEDRDRGR HHHHHHHCCCHHHCH	33.09	22167270
1216	Methylation	SLTEDRDRGRDAVKR HHCCCHHHCHHHHHH	42.83	-
1231	Phosphorylation	EAALPPVSPLKAALS HHCCCCCCHHHHHCC	30.23	19664994
1232	Phosphorylation	AALPPVSPLKAALSE HCCCCCCHHHHHCCH	37.81	18669648
1232 (in isoform 8)	Phosphorylation	-	37.81	-
1234	Ubiquitination	LPPVSPLKAALSEEE CCCCCHHHHHCCHHH	34.69	-
1238	Phosphorylation	SPLKAALSEEELEKK CHHHHHCCHHHHHHH	37.93	29255136
1239 (in isoform 8)	Phosphorylation	-	57.23	-
1241 (in isoform 6)	Ubiquitination	-	59.17	21890473
1244	Acetylation	LSEEELEKKSKAIIE CCHHHHHHHHHHHHH	74.99	23749302
1244	Ubiquitination	LSEEELEKKSKAIIE CCHHHHHHHHHHHHH	74.99	-
1247	Acetylation	EELEKKSKAIIEEYL HHHHHHHHHHHHHHH	53.11	26051181
1247	Malonylation	EELEKKSKAIIEEYL HHHHHHHHHHHHHHH	53.11	26320211
1253	Phosphorylation	SKAIIEEYLHLNDMK HHHHHHHHHCCCHHH	6.14	-
1259	Sulfoxidation	EYLHLNDMKEAVQCV HHHCCCHHHHHHHHH	4.04	30846556
1271	Phosphorylation	QCVQELASPSLLFIF HHHHHHCCCCCEEHH	27.87	23898821
1273	Phosphorylation	VQELASPSLLFIFVR HHHHCCCCCEEHHHH	34.90	23898821
1285	Phosphorylation	FVRHGVESTLERSAI HHHCCHHHHHHHHHH	35.57	23898821
1318 (in isoform 5)	Ubiquitination	-	17.69	21890473
1364 (in isoform 4)	Ubiquitination	-	47.95	21890473
1404	Ubiquitination	REAGLSWKEFLPEGQ HHHCCCHHHHCCCCC	34.90	21906983
1405 (in isoform 1)	Ubiquitination	-	46.27	21890473
1405 (in isoform 3)	Ubiquitination	-	46.27	21890473
1417 (in isoform 6)	Ubiquitination	-	5.93	21890473
1421	Ubiquitination	GAFVAEQKVEYTLGE HHEEEEEEEEEECCC	28.65	-
1424	Phosphorylation	VAEQKVEYTLGEESE EEEEEEEEECCCCCC	15.39	-
1425	Phosphorylation	AEQKVEYTLGEESEA EEEEEEEECCCCCCC	18.12	-
1430	Phosphorylation	EYTLGEESEAPGQRA EEECCCCCCCCCCCC	34.45	-
1436	Methylation	ESEAPGQRALPSEEL CCCCCCCCCCCHHHH	43.96	-
1452	Ubiquitination	RQLEKLLKEGSSNQR HHHHHHHHCCCCCHH	71.16	-
1494 (in isoform 5)	Ubiquitination	-	38.82	21890473
1495	Phosphorylation	YSAIIFETPLRVDVA HHHHHHCCCCCCCHH	19.51	24719451
1513	Acetylation	ARAKLLQKYLCDEQK HHHHHHHHHCCCHHH	39.91	26822725
1513	Ubiquitination	ARAKLLQKYLCDEQK HHHHHHHHHCCCHHH	39.91	-
1526	Phosphorylation	QKELQALYALQALVV HHHHHHHHHHHHHHH	14.31	-
1534	Phosphorylation	ALQALVVTLEQPPNL HHHHHHHHCCCCCCH	19.66	-
1540 (in isoform 4)	Ubiquitination	-	59.39	21890473
1550	Phosphorylation	RMFFDALYDEDVVKE HHHHHHHCCCCCCCC	21.00	-
1567	Ubiquitination	FYSWESSKDPAEQQG CCCCCCCCCHHHHCC	76.61	-
1580	Acetylation	QGKGVALKSVTAFFK CCCCHHHHHHHHHHH	32.89	25953088
1580	Ubiquitination	QGKGVALKSVTAFFK CCCCHHHHHHHHHHH	32.89	2189047
1581 (in isoform 1)	Ubiquitination	-	26.08	21890473
1581 (in isoform 3)	Ubiquitination	-	26.08	21890473
1583	Phosphorylation	GVALKSVTAFFKWLR CHHHHHHHHHHHHHH	25.49	23312004
1587	Acetylation	KSVTAFFKWLREAEE HHHHHHHHHHHHHHH	38.57	26051181
1587	Ubiquitination	KSVTAFFKWLREAEE HHHHHHHHHHHHHHH	38.57	-
1596	Phosphorylation	LREAEEESDHN---- HHHHHHHHCCC----	47.66	9755181
1597	Phosphorylation	REAEEESDHN----- HHHHHHHCCC-----	48.94	18669648

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
647	T	Phosphorylation	Kinase	CDK2	P24941	PSP
895	S	Phosphorylation	Kinase	PAK2	Q13177	PSP
1093	S	Phosphorylation	Kinase	PKCB ISO2	P05771-2	PSP
1147	S	Phosphorylation	Kinase	MAP3K8	P41279	GPS
1185	S	Phosphorylation	Kinase	PKCA	P17252	PSP
1231	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1232	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
1232	S	Phosphorylation	Kinase	MAPK3	P27361	GPS
1239	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
1185	S	Phosphorylation		20068231
Phosphorylation at Ser-1185 by PRKCA induces binding to MKNK1.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of IF4G1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IF4A1_HUMAN	EIF4A1	physical	16648488
IF4A1_HUMAN	EIF4A1	physical	16541103
IF4E_HUMAN	EIF4E	physical	16648488
IF4E_HUMAN	EIF4E	physical	16541103
EIF3A_HUMAN	EIF3A	physical	16541103
EIF3I_HUMAN	EIF3I	physical	16541103
NCBP1_HUMAN	NCBP1	physical	11340157
PABP1_HUMAN	PABPC1	physical	9857202
TRAF2_HUMAN	TRAF2	physical	15743837
IF4G2_HUMAN	EIF4G2	physical	22939629
IF4G3_HUMAN	EIF4G3	physical	22939629
SF3A3_HUMAN	SF3A3	physical	22939629
RAB31_HUMAN	RAB31	physical	22939629
GLPK_HUMAN	GK	physical	21988832
AIMP1_HUMAN	AIMP1	physical	22863883
AIMP2_HUMAN	AIMP2	physical	22863883
MCA3_HUMAN	EEF1E1	physical	22863883
IQGA1_HUMAN	IQGAP1	physical	22863883
PSB8_HUMAN	PSMB8	physical	22863883
PTBP1_HUMAN	PTBP1	physical	22863883
SYQ_HUMAN	QARS	physical	22863883
IF4A1_HUMAN	EIF4A1	physical	26344197
IF4A2_HUMAN	EIF4A2	physical	26344197
FBRL_HUMAN	FBL	physical	26344197
NUP50_HUMAN	NUP50	physical	26344197
PABP1_HUMAN	PABPC1	physical	26344197
PABP4_HUMAN	PABPC4	physical	26344197
DPOE1_HUMAN	POLE	physical	26344197
SF3A3_HUMAN	SF3A3	physical	26344197
SF3B3_HUMAN	SF3B3	physical	26344197
TB182_HUMAN	TNKS1BP1	physical	26344197
IF4E_HUMAN	EIF4E	physical	9418880
IF4A1_HUMAN	EIF4A1	physical	9418880
EIF3B_HUMAN	EIF3B	physical	9418880
IF4A1_HUMAN	EIF4A1	physical	24768540
IF4A2_HUMAN	EIF4A2	physical	24768540
UBP10_HUMAN	USP10	physical	27003362

Drug and Disease Associations

Kegg Disease
OMIM Disease
614251	Parkinson disease 18 (PARK18)
Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of IF4G1_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1095 AND LYS-1188, AND MASSSPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Phosphorylation of eukaryotic translation initiation factor 4G1(eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding toMnk1."; Dobrikov M., Dobrikova E., Shveygert M., Gromeier M.; Mol. Cell. Biol. 31:2947-2959(2011). Cited for: PHOSPHORYLATION AT SER-1185.	21576361 [Abstract]
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1092 AND SER-1231, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1185, AND MASSSPECTROMETRY.	19369195 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-205; THR-207; SER-450;SER-1231 AND SER-1238, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-205; THR-207; THR-223;THR-647; SER-1092; SER-1185; SER-1187; SER-1209; SER-1231 ANDSER-1596, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1231, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Phosphoproteome of resting human platelets."; Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J.,Schuetz C., Walter U., Gambaryan S., Sickmann A.; J. Proteome Res. 7:526-534(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1209, AND MASSSPECTROMETRY.	18088087 [Abstract]
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1231, AND MASSSPECTROMETRY.	18187866 [Abstract]
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry."; Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.; Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1209, AND MASSSPECTROMETRY.	17287340 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1092 AND SER-1231, ANDMASS SPECTROMETRY.	17924679 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1231, AND MASSSPECTROMETRY.	16964243 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1145; SER-1147; SER-1187AND SER-1231, AND MASS SPECTROMETRY.	17081983 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1209 AND SER-1231, ANDMASS SPECTROMETRY.	15302935 [Abstract]
"Immunoaffinity profiling of tyrosine phosphorylation in cancercells."; Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H.,Zha X.-M., Polakiewicz R.D., Comb M.J.; Nat. Biotechnol. 23:94-101(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-594, AND MASSSPECTROMETRY.	15592455 [Abstract]

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