dbPTM

NCOA6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NCOA6_HUMAN
UniProt AC	Q14686
Protein Name	Nuclear receptor coactivator 6
Gene Name	NCOA6
Organism	Homo sapiens (Human).
Sequence Length	2063
Subcellular Localization	Nucleus.
Protein Description	Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins..
Protein Sequence	MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKDFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Acetylation	FKGNIDDKDFKWKLD EECCCCCCCHHHHHH	62.41	19823635
62	Acetylation	NIDDKDFKWKLDAIL CCCCCCHHHHHHHHH	54.26	7706961
95	Asymmetric dimethylarginine	VEPWNSVRVTFNIPR ECCCCCEEEEECCCH	22.91	-
95	Methylation	VEPWNSVRVTFNIPR ECCCCCEEEEECCCH	22.91	24129315
114	Phosphorylation	RLRILAQSNNQQLRD HHHHHHHHCCHHHHH	31.94	26852163
144	Phosphorylation	LALAQNRSQDVRMNG HHHHCCCCCCCCCCC	37.98	-
148	Methylation	QNRSQDVRMNGPMGA CCCCCCCCCCCCCCC	22.57	54557525
160	Methylation	MGAGNSVRMEAGFPM CCCCCCEECCCCCCC	19.62	115484641
169	Phosphorylation	EAGFPMASGPGIIRM CCCCCCCCCCCEEEC	38.99	22210691
191	Phosphorylation	IPPGGNVSSSMMAPG ECCCCCCCHHCCCCC	22.24	22210691
413	Dimethylation	SLQGGPSRVPTPLQQ HCCCCCCCCCCCCCC	41.38	-
413	Methylation	SLQGGPSRVPTPLQQ HCCCCCCCCCCCCCC	41.38	30762657
416	Phosphorylation	GGPSRVPTPLQQPHL CCCCCCCCCCCCCCC	33.50	28348404
667	Phosphorylation	QMMVNPPSQNLGPSP CCCCCCCCCCCCCCC	32.72	26074081
673	Phosphorylation	PSQNLGPSPQRMTPP CCCCCCCCCCCCCCH	31.69	26074081
678	Phosphorylation	GPSPQRMTPPKQMLS CCCCCCCCCHHHHHH	38.33	26074081
881	Phosphorylation	FPVNKDVTLTSPLLV CCCCCCCCCCCHHHH	34.16	29496963
883	Phosphorylation	VNKDVTLTSPLLVNL CCCCCCCCCHHHHHH	20.94	28450419
884	Phosphorylation	NKDVTLTSPLLVNLL CCCCCCCCHHHHHHH	19.36	28450419
926	Phosphorylation	PPRKKKNSQQDLNTP CCCCCCCCCCCCCCC	37.79	30108239
932	Phosphorylation	NSQQDLNTPDTRPAG CCCCCCCCCCCCCCC	29.82	29978859
935	Phosphorylation	QDLNTPDTRPAGLEE CCCCCCCCCCCCCCC	39.49	30108239
967	O-linked_Glycosylation	GPKLPEFSNRPPGYP CCCCCCCCCCCCCCC	30.21	30059200
1047	Asymmetric dimethylarginine	QQDPKSVRLPVSQNV HCCCCCCCCCCCCCC	40.12	-
1047	Methylation	QQDPKSVRLPVSQNV HCCCCCCCCCCCCCC	40.12	54549399
1058	Asymmetric dimethylarginine	SQNVHPPRGPLNPDS CCCCCCCCCCCCCCC	64.91	-
1058	Methylation	SQNVHPPRGPLNPDS CCCCCCCCCCCCCCC	64.91	54548503
1091	Phosphorylation	GPASVPPSPDKQRMP CCCCCCCCCCCCCCC	39.39	21552520
1096	Asymmetric dimethylarginine	PPSPDKQRMPMPVNT CCCCCCCCCCCCCCC	36.59	-
1096	Methylation	PPSPDKQRMPMPVNT CCCCCCCCCCCCCCC	36.59	54549401
1103	Phosphorylation	RMPMPVNTPLGSNSR CCCCCCCCCCCCCCC	21.81	25278378
1107	Phosphorylation	PVNTPLGSNSRKMVY CCCCCCCCCCCCCEE	39.04	25278378
1109	Phosphorylation	NTPLGSNSRKMVYQE CCCCCCCCCCCEEEC	34.67	22210691
1211	Phosphorylation	TQTSRPKTPNRASPR CCCCCCCCCCCCCCC	28.60	28348404
1216	O-linked_Glycosylation	PKTPNRASPRPYYPQ CCCCCCCCCCCCCCC	20.43	30059200
1216	Phosphorylation	PKTPNRASPRPYYPQ CCCCCCCCCCCCCCC	20.43	28348404
1220	Phosphorylation	NRASPRPYYPQTPNN CCCCCCCCCCCCCCC	29.11	30108239
1221	Phosphorylation	RASPRPYYPQTPNNR CCCCCCCCCCCCCCC	7.49	30108239
1224	O-linked_Glycosylation	PRPYYPQTPNNRPPS CCCCCCCCCCCCCCC	24.39	30059200
1224	Phosphorylation	PRPYYPQTPNNRPPS CCCCCCCCCCCCCCC	24.39	30108239
1231	O-linked_Glycosylation	TPNNRPPSTEPSEIS CCCCCCCCCCCCCCC	48.35	30059200
1231	Phosphorylation	TPNNRPPSTEPSEIS CCCCCCCCCCCCCCC	48.35	26657352
1232	O-linked_Glycosylation	PNNRPPSTEPSEISL CCCCCCCCCCCCCCC	58.66	30059200
1232	Phosphorylation	PNNRPPSTEPSEISL CCCCCCCCCCCCCCC	58.66	30108239
1235	O-linked_Glycosylation	RPPSTEPSEISLSPE CCCCCCCCCCCCCHH	41.13	30059200
1235	Phosphorylation	RPPSTEPSEISLSPE CCCCCCCCCCCCCHH	41.13	24719451
1238	Phosphorylation	STEPSEISLSPERLN CCCCCCCCCCHHHHC	20.81	29523821
1240	Phosphorylation	EPSEISLSPERLNAS CCCCCCCCHHHHCHH	20.23	30108239
1291	Phosphorylation	GQAPSNLTMNPSNFA CCCCCCCCCCHHHCC	21.10	30175587
1299	Phosphorylation	MNPSNFATPQTHKLD CCHHHCCCCCCEECC	16.28	25159151
1304	Acetylation	FATPQTHKLDSVVVN CCCCCCEECCEEEEC	58.33	26051181
1307	Phosphorylation	PQTHKLDSVVVNSGK CCCEECCEEEECCCC	27.52	20068231
1312	Phosphorylation	LDSVVVNSGKQSNSG CCEEEECCCCCCCCC	35.44	21815630
1314	Acetylation	SVVVNSGKQSNSGAT EEEECCCCCCCCCCC	50.83	25953088
1316	Phosphorylation	VVNSGKQSNSGATKR EECCCCCCCCCCCCC	36.13	20068231
1318	Phosphorylation	NSGKQSNSGATKRAS CCCCCCCCCCCCCCC	34.74	20068231
1321	Phosphorylation	KQSNSGATKRASPSN CCCCCCCCCCCCCCC	25.29	20068231
1322	Acetylation	QSNSGATKRASPSNS CCCCCCCCCCCCCCC	45.49	25953088
1325	Phosphorylation	SGATKRASPSNSRRS CCCCCCCCCCCCCCC	32.66	-
1339	Acetylation	SSPGSSRKTTPSPGR CCCCCCCCCCCCCCC	59.71	30590693
1340	Phosphorylation	SPGSSRKTTPSPGRQ CCCCCCCCCCCCCCC	42.71	27794612
1341	Phosphorylation	PGSSRKTTPSPGRQN CCCCCCCCCCCCCCC	25.46	27794612
1343	Phosphorylation	SSRKTTPSPGRQNSK CCCCCCCCCCCCCCC	37.58	30576142
1349	Phosphorylation	PSPGRQNSKAPKLTL CCCCCCCCCCCCEEH	23.12	28102081
1353	Acetylation	RQNSKAPKLTLASQT CCCCCCCCEEHHHHH	59.99	25953088
1377	Phosphorylation	LPRNVLVSPTPLANP CCCCEEECCCCCCCC	20.92	28348404
1379	Phosphorylation	RNVLVSPTPLANPPV CCEEECCCCCCCCCC	24.35	28348404
1430	Phosphorylation	QDSDCQNSQSRKEQV CCCCCCCCHHHHHHH	12.03	25627689
1442	Acetylation	EQVNIELKAVPAQEV HHHCEEEEECCHHHE	34.25	23236377
1458	Phosphorylation	MVVPEDQSKKDGQPS EECCCCCCCCCCCCC	54.73	26074081
1465	Phosphorylation	SKKDGQPSDPNKLPS CCCCCCCCCCCCCCC	58.79	26074081
1472	Phosphorylation	SDPNKLPSVEENKNL CCCCCCCCHHHHCCC	53.23	26074081
1481	Phosphorylation	EENKNLVSPAMREAP HHHCCCCCHHHHHCC	15.31	30266825
1516	Phosphorylation	GLTDLEVTPPVVSGE CCCCCEECCCCCCHH	16.70	25159151
1521	Phosphorylation	EVTPPVVSGEDLKKA EECCCCCCHHHHHHH	36.38	25627689
1641	O-linked_Glycosylation	AGSKVMVSEGQSAAQ CCCEEEEECCHHHHH	20.22	30059200
1645	O-linked_Glycosylation	VMVSEGQSAAQSNAR EEEECCHHHHHHCCC	36.11	30059200
1719	Phosphorylation	PVPPNALSSSPAPNI CCCCCCCCCCCCCCC	26.76	28348404
1720	Phosphorylation	VPPNALSSSPAPNIQ CCCCCCCCCCCCCCC	40.99	25159151
1721	Phosphorylation	PPNALSSSPAPNIQT CCCCCCCCCCCCCCC	23.00	25627689
1736	Phosphorylation	GRPLVLSSRATPVQL CCCEEECCCCCCCCC	23.05	24719451
1739	Phosphorylation	LVLSSRATPVQLPSP EEECCCCCCCCCCCC	23.92	22199227
1745	Phosphorylation	ATPVQLPSPPCTSSP CCCCCCCCCCCCCCC	50.49	25159151
1749	Phosphorylation	QLPSPPCTSSPVVPS CCCCCCCCCCCCCCC	37.70	23663014
1750	Phosphorylation	LPSPPCTSSPVVPSH CCCCCCCCCCCCCCC	39.08	23663014
1751	Phosphorylation	PSPPCTSSPVVPSHP CCCCCCCCCCCCCCC	11.99	23663014
1756	Phosphorylation	TSSPVVPSHPPVQQV CCCCCCCCCCCHHHH	36.70	22199227
1786	Phosphorylation	ADQNTLPSSQSTTMV CCCCCCCCCCCEEEE	44.09	25850435
1787	Phosphorylation	DQNTLPSSQSTTMVS CCCCCCCCCCEEEEE	26.64	25850435
1789	Phosphorylation	NTLPSSQSTTMVSPL CCCCCCCCEEEEECC	28.00	25850435
1790	Phosphorylation	TLPSSQSTTMVSPLL CCCCCCCEEEEECCC	15.98	25850435
1791	Phosphorylation	LPSSQSTTMVSPLLT CCCCCCEEEEECCCC	22.33	25850435
1794	Phosphorylation	SQSTTMVSPLLTNSP CCCEEEEECCCCCCC	10.06	25850435
1798	Phosphorylation	TMVSPLLTNSPGSSG EEEECCCCCCCCCCC	41.14	25850435
1800	Phosphorylation	VSPLLTNSPGSSGNR EECCCCCCCCCCCCC	25.96	25850435
1803	Phosphorylation	LLTNSPGSSGNRRSP CCCCCCCCCCCCCCC	38.16	25850435
1804	Phosphorylation	LTNSPGSSGNRRSPV CCCCCCCCCCCCCCC	46.10	25850435
1809	Phosphorylation	GSSGNRRSPVSSSKG CCCCCCCCCCCCCCC	26.81	28985074
1819	Acetylation	SSSKGKGKVDKIGQI CCCCCCCCCCHHHHH	51.23	25953088
1822	Acetylation	KGKGKVDKIGQILLT CCCCCCCHHHHHHHH	52.29	23236377
1830	Acetylation	IGQILLTKACKKVTG HHHHHHHHHHHHHHC	52.32	25953088
1876	Phosphorylation	QLSTELDSKTPTPPA HHHHHHCCCCCCCCC	51.56	24275569
1878	Phosphorylation	STELDSKTPTPPAPT HHHHCCCCCCCCCCC	36.02	28985074
1880	Phosphorylation	ELDSKTPTPPAPTLL HHCCCCCCCCCCCEE	47.32	25849741
1885	Phosphorylation	TPTPPAPTLLKMTSS CCCCCCCCEEEECCC	46.99	23186163
1890	Phosphorylation	APTLLKMTSSPVGPG CCCEEEECCCCCCCC	25.19	30266825
1891	Phosphorylation	PTLLKMTSSPVGPGT CCEEEECCCCCCCCC	29.19	30266825
1892	Phosphorylation	TLLKMTSSPVGPGTA CEEEECCCCCCCCCC	17.90	30266825
1898	Phosphorylation	SSPVGPGTASAGPSL CCCCCCCCCCCCCCC	22.14	30266825
1900	Phosphorylation	PVGPGTASAGPSLPG CCCCCCCCCCCCCCC	33.33	30266825
1904	Phosphorylation	GTASAGPSLPGGALP CCCCCCCCCCCCCCC	46.40	30266825
1916	O-linked_Glycosylation	ALPTSVRSIVTTLVP CCCCCHHHHHHHCCC	21.18	30059200
1916	Phosphorylation	ALPTSVRSIVTTLVP CCCCCHHHHHHHCCC	21.18	-
1920	O-linked_Glycosylation	SVRSIVTTLVPSELI CHHHHHHHCCCHHHH	18.18	30059200
1932	O-linked_Glycosylation	ELISAVPTTKSNHGG HHHHCCCCCCCCCCC	40.01	30059200
1933	O-linked_Glycosylation	LISAVPTTKSNHGGI HHHCCCCCCCCCCCC	26.80	30059200
2018	Phosphorylation	KIPGRRNSRTEEPTV CCCCCCCCCCCCCCC	38.47	23401153
2020	Phosphorylation	PGRRNSRTEEPTVAS CCCCCCCCCCCCCCC	44.51	23927012
2024	Phosphorylation	NSRTEEPTVASESVE CCCCCCCCCCCHHHH	31.80	23927012
2027	Phosphorylation	TEEPTVASESVENGH CCCCCCCCHHHHCCC	26.52	23663014
2029	Phosphorylation	EPTVASESVENGHRK CCCCCCHHHHCCCCC	32.03	23927012
2038	Phosphorylation	ENGHRKRSSRPASAS HCCCCCCCCCCCCCC	33.46	23312004
2039	Phosphorylation	NGHRKRSSRPASASS CCCCCCCCCCCCCCC	46.44	23312004
2043	Phosphorylation	KRSSRPASASSSTKD CCCCCCCCCCCCHHH	31.22	29978859
2045	Phosphorylation	SSRPASASSSTKDIT CCCCCCCCCCHHHHH	23.48	29978859
2046	Phosphorylation	SRPASASSSTKDITS CCCCCCCCCHHHHHH	41.57	29978859
2047	Phosphorylation	RPASASSSTKDITSA CCCCCCCCHHHHHHH	36.66	29978859
2048	Phosphorylation	PASASSSTKDITSAV CCCCCCCHHHHHHHH	34.38	29978859
2049	Acetylation	ASASSSTKDITSAVQ CCCCCCHHHHHHHHH	49.43	23236377
2053	Phosphorylation	SSTKDITSAVQSKRR CCHHHHHHHHHHHHH	27.12	-
2057	Phosphorylation	DITSAVQSKRRKSK- HHHHHHHHHHHHCC-	22.87	-
2058	Acetylation	ITSAVQSKRRKSK-- HHHHHHHHHHHCC--	38.85	25953088
2062	Phosphorylation	VQSKRRKSK------ HHHHHHHCC------	41.61	26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
884	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
884	S	Phosphorylation	Kinase	MAPK-FAMILY	-	GPS
884	S	Phosphorylation	Kinase	MAPK	-	Uniprot

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
884	S	Phosphorylation		11773444
Phosphorylation on Ser-884 leads to a strong decrease in binding to ESR1 and ESR2.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NCOA6_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ASCL2_HUMAN	ASCL2	physical	12482968
KMT2C_HUMAN	KMT2C	physical	12482968
RBBP5_HUMAN	RBBP5	physical	12482968
ANDR_HUMAN	AR	physical	14645241
FOS_HUMAN	FOS	physical	10847592
JUN_HUMAN	JUN	physical	10847592
NFKB1_HUMAN	NFKB1	physical	10847592
TF65_HUMAN	RELA	physical	10847592
SRF_MOUSE	Srf	physical	10847592
SRF_HUMAN	SRF	physical	10847592
ESR2_HUMAN	ESR2	physical	11158331
RARA_HUMAN	RARA	physical	11158331
THB_HUMAN	THRB	physical	11158331
CBP_HUMAN	CREBBP	physical	10567404
ESR1_HUMAN	ESR1	physical	10567404
GCR_HUMAN	NR3C1	physical	10567404
RARA_HUMAN	RARA	physical	10567404
THA_HUMAN	THRA	physical	10567404
CBP_HUMAN	CREBBP	physical	11158331
NR1I3_MOUSE	Nr1i3	physical	15764585
NR1H2_HUMAN	NR1H2	physical	11158331
RB_HUMAN	RB1	physical	14645241
H32_HUMAN	HIST2H3C	physical	12482968
RXRA_HUMAN	RXRA	physical	10567404
RXRA_HUMAN	RXRA	physical	11158331
CEBPA_HUMAN	CEBPA	physical	11302752
THA_HUMAN	THRA	physical	10847592
RXRA_HUMAN	RXRA	physical	14578865
ASCC1_HUMAN	ASCC1	physical	10567404
SRC_HUMAN	SRC	physical	10847592
TBP_HUMAN	TBP	physical	10567404
TF2AA_HUMAN	GTF2A1	physical	10567404
THB_HUMAN	THRB	physical	10567404
TNR5_HUMAN	CD40	physical	10847592
PRKDC_HUMAN	PRKDC	physical	10823961
XRCC5_HUMAN	XRCC5	physical	10823961
XRCC6_HUMAN	XRCC6	physical	10823961
MED23_HUMAN	MED23	physical	10823961
EP300_HUMAN	EP300	physical	10823961
TGS1_HUMAN	TGS1	physical	11912212
ZN335_HUMAN	ZNF335	physical	12215545
ESR1_HUMAN	ESR1	physical	11773444
ESR2_HUMAN	ESR2	physical	11773444
XRCC6_HUMAN	XRCC6	physical	12519782
XRCC5_HUMAN	XRCC5	physical	12519782
NUMA1_HUMAN	NUMA1	physical	12519782
PARP1_HUMAN	PARP1	physical	12519782
LTOR5_HUMAN	LAMTOR5	physical	14578865
TRXR2_HUMAN	TXNRD2	physical	11158331
NCOR2_HUMAN	NCOR2	physical	11158331
SRC_HUMAN	SRC	physical	11158331
KMT2B_HUMAN	KMT2B	physical	19047629
KMT2C_HUMAN	KMT2C	physical	19047629
KDM6A_HUMAN	KDM6A	physical	19047629
UTY_HUMAN	UTY	physical	19047629
PAXI1_HUMAN	PAXIP1	physical	19047629
ASH2L_HUMAN	ASH2L	physical	19047629
RBBP5_HUMAN	RBBP5	physical	19047629
DPY30_HUMAN	DPY30	physical	19047629
WDR5_HUMAN	WDR5	physical	19047629
WDR5_HUMAN	WDR5	physical	17021013
HNF4A_HUMAN	HNF4A	physical	18552123
PRGC1_HUMAN	PPARGC1A	physical	18552123
RBBP5_HUMAN	RBBP5	physical	17925232
WDR5_HUMAN	WDR5	physical	17925232
PAXI1_HUMAN	PAXIP1	physical	17925232
ASH2L_HUMAN	ASH2L	physical	17925232
PAXI1_HUMAN	PAXIP1	physical	17500065
NCOA6_HUMAN	NCOA6	physical	17500065
ASH2L_HUMAN	ASH2L	physical	17500065
RBBP5_HUMAN	RBBP5	physical	17500065
NR1H4_HUMAN	NR1H4	physical	21330447
PPARG_HUMAN	PPARG	physical	15604093
RORG_HUMAN	RORC	physical	15604093
RANB9_HUMAN	RANBP9	physical	15604093
NR1H3_HUMAN	NR1H3	physical	15604093
NR1H2_HUMAN	NR1H2	physical	15604093
FHOD1_HUMAN	FHOD1	physical	15604093
NCOA6_HUMAN	NCOA6	physical	10866662
GCR_HUMAN	NR3C1	physical	10866662
RARA_HUMAN	RARA	physical	10866662
RXRA_HUMAN	RXRA	physical	10866662
ESR1_HUMAN	ESR1	physical	10866662
VDR_HUMAN	VDR	physical	10866662
CBP_HUMAN	CREBBP	physical	10866662
HNF4A_HUMAN	HNF4A	physical	21292004
NR1I2_HUMAN	NR1I2	physical	21292004
GRIP1_HUMAN	GRIP1	physical	21292004
NCOA1_HUMAN	NCOA1	physical	21292004
MED1_HUMAN	MED1	physical	21292004
RAGP1_HUMAN	RANGAP1	physical	22939629
THA_HUMAN	THRA	physical	10681503
ESR1_HUMAN	ESR1	physical	10681503
RXRA_HUMAN	RXRA	physical	10681503
ASH2L_HUMAN	ASH2L	physical	23870121
RBBP5_HUMAN	RBBP5	physical	23870121
WDR5_HUMAN	WDR5	physical	23870121
HCFC1_HUMAN	HCFC1	physical	23870121
NCOA1_HUMAN	NCOA1	physical	10567404
NCOA1_HUMAN	NCOA1	physical	12482968
NCOA2_HUMAN	NCOA2	physical	12482968
TBA1A_HUMAN	TUBA1A	physical	12482968

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NCOA6_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1321, AND MASSSPECTROMETRY.	15302935 [Abstract]

show