CNDP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CNDP1_HUMAN
• UniProt AC: Q96KN2
• Protein Name: Beta-Ala-His dipeptidase
• Gene Name: CNDP1
• Organism: Homo sapiens (Human).
• Sequence Length: 507
• Subcellular Localization: Secreted.
• Protein Sequence: MDPKLGRMAASLLAVLLLLLERGMFSSPSPPPALLEKVFQYIDLHQDEFVQTLKEWVAIESDSVQPVPRFRQELFRMMAVAADTLQRLGARVASVDMGPQQLPDGQSLPIPPIILAELGSDPTKGTVCFYGHLDVQPADRGDGWLTDPYVLTEVDGKLYGRGATDNKGPVLAWINAVSAFRALEQDLPVNIKFIIEGMEEAGSVALEELVEKEKDRFFSGVDYIVISDNLWISQRKPAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHEPMADLVALLGSLVDSSGHILVPGIYDEVVPLTEEEINTYKAIHLDLEEYRNSSRVEKFLFDTKEEILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNVSAVEKQVTRHLEDVFSKRNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRAIRTVFGTEPDMIRDGSTIPIAKMFQEIVHKSVVLIPLGAVDDGEHSQNEKINRWNYIEGTKLFAAFFLEMAQLH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	O-linked_Glycosylation	RGMFSSPSPPPALLE CCCCCCCCCCHHHHH	52.57	OGP
61	Phosphorylation	KEWVAIESDSVQPVP HHHHCCCCCCCCCCH	29.13	26074081
63	Phosphorylation	WVAIESDSVQPVPRF HHCCCCCCCCCCHHH	31.75	26074081
146	O-linked_Glycosylation	DRGDGWLTDPYVLTE CCCCCCCCCCEEEEE	28.55	OGP
219	Phosphorylation	KEKDRFFSGVDYIVI HHHHCCCCCCCEEEE	34.88	-
322	N-linked_Glycosylation	LDLEEYRNSSRVEKF CCHHHHHCCHHHHHH	43.36	16335952
346	Phosphorylation	MHLWRYPSLSIHGIE HHHHHCCCCEECCCC	26.30	-
363	Phosphorylation	FDEPGTKTVIPGRVI CCCCCCEEEECCEEE	24.41	-
382	N-linked_Glycosylation	IRLVPHMNVSAVEKQ EEECCCCCHHHHHHH	22.89	16335952
382	N-linked_Glycosylation	IRLVPHMNVSAVEKQ EEECCCCCHHHHHHH	22.89	16335952
425	Phosphorylation	WIANIDDTQYLAAKR HHCCCCHHHHHHHHH	18.50	24719451
427	Phosphorylation	ANIDDTQYLAAKRAI CCCCHHHHHHHHHHH	10.62	24719451
440	Phosphorylation	AIRTVFGTEPDMIRD HHHHHHCCCHHHCCC	32.64	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CNDP1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CNDP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CNDP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
POTEF_HUMAN	POTEF	physical	26186194
RAB3B_HUMAN	RAB3B	physical	26186194
CNDP2_HUMAN	CNDP2	physical	26186194
GDC_HUMAN	SLC25A16	physical	26186194
CX7A2_HUMAN	COX7A2	physical	26186194
PIGM_HUMAN	PIGM	physical	26186194
ARF5_HUMAN	ARF5	physical	26186194
WRB_HUMAN	WRB	physical	26186194
MANEA_HUMAN	MANEA	physical	26186194
SCD5_HUMAN	SCD5	physical	26186194
2B1F_HUMAN	HLA-DRB1	physical	26186194
2B13_HUMAN	HLA-DRB1	physical	26186194
2B1G_HUMAN	HLA-DRB1	physical	26186194
POTEF_HUMAN	POTEF	physical	28514442
CNDP2_HUMAN	CNDP2	physical	28514442
MOT10_HUMAN	SLC16A10	physical	28514442
RAB3B_HUMAN	RAB3B	physical	28514442
MANEA_HUMAN	MANEA	physical	28514442
GDC_HUMAN	SLC25A16	physical	28514442
CX7A2_HUMAN	COX7A2	physical	28514442
PIGM_HUMAN	PIGM	physical	28514442
ADT3_HUMAN	SLC25A6	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

N-linked Glycosylation

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction,hydrazide chemistry, and mass spectrometry.";
Liu T., Qian W.-J., Gritsenko M.A., Camp D.G. II, Monroe M.E.,Moore R.J., Smith R.D.;
J. Proteome Res. 4:2070-2080(2005).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-322 AND ASN-382, AND MASSSPECTROMETRY.
PubMed: 16335952