dbPTM

SASH1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SASH1_HUMAN
UniProt AC	O94885
Protein Name	SAM and SH3 domain-containing protein 1
Gene Name	SASH1
Organism	Homo sapiens (Human).
Sequence Length	1247
Subcellular Localization
Protein Description	May have a role in a signaling pathway. Could act as a tumor suppressor..
Protein Sequence	MEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCFSDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKGIMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTWGAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSVKETMRKRMSKKYSSSVSEQDSGLDGMPGSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQSGSQEKLLVDSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQGQEEGRLGGGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDDLQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPALTRKVSCARGVDLETLTENKLHAEGIDLTEEPYSDKHGRCGIPEALVQRYAEDLDQPERDVAANMDQIRVKQLRKQHRMAIPSGGLTEICRKPVSPGCISSVSDWLISIGLPMYAGTLSTAGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLFKLPPGPEAM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
69	Phosphorylation	LAQQYADYYNTCFSD HHHHHHHHHHHHHHH	7.16	-
90	Phosphorylation	ELRKRRVSQDLEVEK HHHHHHHHCCCCCCC	19.03	29255136
101	Phosphorylation	EVEKPDASPTSLQLR CCCCCCCCCCHHHHH	35.77	29255136
103	Phosphorylation	EKPDASPTSLQLRSQ CCCCCCCCHHHHHHH	39.30	29255136
104	Phosphorylation	KPDASPTSLQLRSQI CCCCCCCHHHHHHHH	19.94	29255136
109	Phosphorylation	PTSLQLRSQIEESLG CCHHHHHHHHHHHHC	44.07	23403867
114	Phosphorylation	LRSQIEESLGFCSAV HHHHHHHHHCCCCCC	22.47	21712546
119	Phosphorylation	EESLGFCSAVSTPEV HHHHCCCCCCCCHHH	29.46	23403867
122	Phosphorylation	LGFCSAVSTPEVERK HCCCCCCCCHHHHHC	37.65	22617229
123	Phosphorylation	GFCSAVSTPEVERKN CCCCCCCCHHHHHCC	19.50	23403867
135	Phosphorylation	RKNPLHKSNSEDSSV HCCCCCCCCCCCCCC	34.54	23403867
137	Phosphorylation	NPLHKSNSEDSSVGK CCCCCCCCCCCCCCC	50.28	25849741
140	Phosphorylation	HKSNSEDSSVGKGDW CCCCCCCCCCCCCCH	23.91	26699800
141	Phosphorylation	KSNSEDSSVGKGDWK CCCCCCCCCCCCCHH	47.40	23403867
169	Phosphorylation	QKGIMRQTSKGEDVG CCCCCCCCCCCCCHH	23.26	26657352
170	Phosphorylation	KGIMRQTSKGEDVGY CCCCCCCCCCCCHHH	30.26	26657352
177	Phosphorylation	SKGEDVGYVASEITM CCCCCHHHEEEEECC	7.84	28857561
180	Phosphorylation	EDVGYVASEITMSDE CCHHHEEEEECCCHH	21.35	28102081
183	Phosphorylation	GYVASEITMSDEERI HHEEEEECCCHHHHH	13.43	27794612
185	Phosphorylation	VASEITMSDEERIQL EEEEECCCHHHHHHH	32.97	27794612
211	Ubiquitination	EEALARLKEYEAQHR HHHHHHHHHHHHHHH	53.34	-
213	Phosphorylation	ALARLKEYEAQHRQS HHHHHHHHHHHHHHH	18.25	28152594
213	Ubiquitination	ALARLKEYEAQHRQS HHHHHHHHHHHHHHH	18.25	22817900
214	Ubiquitination	LARLKEYEAQHRQSA HHHHHHHHHHHHHHC	42.83	22817900
216	Ubiquitination	RLKEYEAQHRQSAAL HHHHHHHHHHHHCCC	21.98	22817900
232	Phosphorylation	PADWPDGSYPTFDGS CCCCCCCCCCCCCCC	35.01	29449344
233	Phosphorylation	ADWPDGSYPTFDGSS CCCCCCCCCCCCCCC	16.30	29449344
235	Phosphorylation	WPDGSYPTFDGSSNC CCCCCCCCCCCCCCC	26.56	25850435
239	Phosphorylation	SYPTFDGSSNCNSRE CCCCCCCCCCCCCCC	21.88	25850435
240	Phosphorylation	YPTFDGSSNCNSREQ CCCCCCCCCCCCCCC	51.43	25850435
244	Phosphorylation	DGSSNCNSREQSDDE CCCCCCCCCCCCCCC	39.12	25850435
248	Phosphorylation	NCNSREQSDDETEES CCCCCCCCCCCCHHH	42.13	29255136
252	Phosphorylation	REQSDDETEESVKFK CCCCCCCCHHHHHHH	52.64	20873877
255	Phosphorylation	SDDETEESVKFKRLH CCCCCHHHHHHHHHH	25.11	23927012
267	Phosphorylation	RLHKLVNSTRRVRKK HHHHHHHHHHHHHHH	18.80	24719451
268	Phosphorylation	LHKLVNSTRRVRKKL HHHHHHHHHHHHHHH	19.79	33259812
285	Phosphorylation	VEEMKKPSTEGGEEH HHHCCCCCCCCCCCC	48.23	25849741
286	Phosphorylation	EEMKKPSTEGGEEHV HHCCCCCCCCCCCCC	47.37	23403867
297	Phosphorylation	EEHVFENSPVLDERS CCCCCCCCCCCCHHH	14.80	25849741
307	Phosphorylation	LDERSALYSGVHKKP CCHHHHHCCCCCCCC	11.77	26356563
308	Phosphorylation	DERSALYSGVHKKPL CHHHHHCCCCCCCCC	34.88	28555341
320	Phosphorylation	KPLFFDGSPEKPPED CCCCCCCCCCCCCCC	31.56	25002506
328	Ubiquitination	PEKPPEDDSDSLTTS CCCCCCCCCCCCCCC	53.32	22817900
329	Phosphorylation	EKPPEDDSDSLTTSP CCCCCCCCCCCCCCC	41.23	30576142
329	Ubiquitination	EKPPEDDSDSLTTSP CCCCCCCCCCCCCCC	41.23	22817900
331	Phosphorylation	PPEDDSDSLTTSPSS CCCCCCCCCCCCCCC	31.41	25002506
331	Ubiquitination	PPEDDSDSLTTSPSS CCCCCCCCCCCCCCC	31.41	22817900
333	Phosphorylation	EDDSDSLTTSPSSSS CCCCCCCCCCCCCCC	29.22	28857561
334	Phosphorylation	DDSDSLTTSPSSSSL CCCCCCCCCCCCCCC	43.89	28857561
335	Phosphorylation	DSDSLTTSPSSSSLD CCCCCCCCCCCCCCC	19.97	28857561
335	Ubiquitination	DSDSLTTSPSSSSLD CCCCCCCCCCCCCCC	19.97	22817900
336	Ubiquitination	SDSLTTSPSSSSLDT CCCCCCCCCCCCCCC	35.82	22817900
337	Phosphorylation	DSLTTSPSSSSLDTW CCCCCCCCCCCCCCC	42.49	25002506
338	Phosphorylation	SLTTSPSSSSLDTWG CCCCCCCCCCCCCCC	27.59	28857561
338	Ubiquitination	SLTTSPSSSSLDTWG CCCCCCCCCCCCCCC	27.59	22817900
339	Phosphorylation	LTTSPSSSSLDTWGA CCCCCCCCCCCCCCC	38.98	30576142
340	Phosphorylation	TTSPSSSSLDTWGAG CCCCCCCCCCCCCCC	32.01	28857561
343	Phosphorylation	PSSSSLDTWGAGRKL CCCCCCCCCCCCHHH	30.96	25002506
353	Phosphorylation	AGRKLVKTFSKGESR CCHHHHHHCCCCCCC	26.17	28857561
355	Phosphorylation	RKLVKTFSKGESRGL HHHHHHCCCCCCCCC	45.01	24719451
371	Phosphorylation	KPPKKMGTFFSYPEE CCCHHCCCCCCCCHH	20.29	28985074
374	Phosphorylation	KKMGTFFSYPEEEKA HHCCCCCCCCHHHHH	35.27	25106551
375	Phosphorylation	KMGTFFSYPEEEKAQ HCCCCCCCCHHHHHH	14.98	32142685
376	Ubiquitination	MGTFFSYPEEEKAQK CCCCCCCCHHHHHHH	41.13	22817900
377	Ubiquitination	GTFFSYPEEEKAQKV CCCCCCCHHHHHHHH	71.24	22817900
379	Ubiquitination	FFSYPEEEKAQKVSR CCCCCHHHHHHHHHH	52.62	22817900
383	Phosphorylation	PEEEKAQKVSRSLTE CHHHHHHHHHHHCCC	47.22	33259812
385	Phosphorylation	EEKAQKVSRSLTEGE HHHHHHHHHHCCCCH	24.16	23403867
387	Phosphorylation	KAQKVSRSLTEGEMK HHHHHHHHCCCCHHH	31.94	29255136
389	Phosphorylation	QKVSRSLTEGEMKKG HHHHHHCCCCHHHCC	43.10	26657352
390	Phosphorylation	KVSRSLTEGEMKKGL HHHHHCCCCHHHCCC	59.45	33259812
399	Phosphorylation	EMKKGLGSLSHGRTC HHHCCCCCCCCCCCC	31.57	23403867
401	Phosphorylation	KKGLGSLSHGRTCSF HCCCCCCCCCCCCCC	26.12	29514088
405	Phosphorylation	GSLSHGRTCSFGGFD CCCCCCCCCCCCCEE	19.66	30266825
407	Phosphorylation	LSHGRTCSFGGFDLT CCCCCCCCCCCEECC	26.72	19664994
407	Ubiquitination	LSHGRTCSFGGFDLT CCCCCCCCCCCEECC	26.72	22817900
408	Ubiquitination	SHGRTCSFGGFDLTN CCCCCCCCCCEECCC	13.93	22817900
410	Ubiquitination	GRTCSFGGFDLTNRS CCCCCCCCEECCCCE	15.75	22817900
414	Phosphorylation	SFGGFDLTNRSLHVG CCCCEECCCCEEEEC	30.36	23403867
417	Phosphorylation	GFDLTNRSLHVGSNN CEECCCCEEEECCCC	25.54	29514088
422	Phosphorylation	NRSLHVGSNNSDPMG CCEEEECCCCCCCCC	31.58	29514088
431	Phosphorylation	NSDPMGKEGDFVYKE CCCCCCCCCCCEEEH	59.26	33259812
436	Phosphorylation	GKEGDFVYKEVIKSP CCCCCCEEEHHHCCC	11.04	27642862
442	Phosphorylation	VYKEVIKSPTASRIS EEEHHHCCCCCHHCC	19.16	29255136
444	Phosphorylation	KEVIKSPTASRISLG EHHHCCCCCHHCCCC	44.34	28176443
446	Phosphorylation	VIKSPTASRISLGKK HHCCCCCHHCCCCHH	32.40	23403867
449	Phosphorylation	SPTASRISLGKKVKS CCCCHHCCCCHHHHH	29.93	29514088
452	Ubiquitination	ASRISLGKKVKSVKE CHHCCCCHHHHHHHH	60.74	22817900
453	Ubiquitination	SRISLGKKVKSVKET HHCCCCHHHHHHHHH	53.77	22817900
455	Ubiquitination	ISLGKKVKSVKETMR CCCCHHHHHHHHHHH	59.41	22817900
456	Phosphorylation	SLGKKVKSVKETMRK CCCHHHHHHHHHHHH	41.21	22210691
460	Phosphorylation	KVKSVKETMRKRMSK HHHHHHHHHHHHHHH	19.29	22210691
462	Phosphorylation	KSVKETMRKRMSKKY HHHHHHHHHHHHHHH	30.74	33259812
469	Phosphorylation	RKRMSKKYSSSVSEQ HHHHHHHHHCCCCHH	19.95	23403867
470	Phosphorylation	KRMSKKYSSSVSEQD HHHHHHHHCCCCHHC	25.64	23403867
471	Phosphorylation	RMSKKYSSSVSEQDS HHHHHHHCCCCHHCC	31.50	23403867
472	Phosphorylation	MSKKYSSSVSEQDSG HHHHHHCCCCHHCCC	24.58	23403867
474	Phosphorylation	KKYSSSVSEQDSGLD HHHHCCCCHHCCCCC	31.33	23403867
478	Phosphorylation	SSVSEQDSGLDGMPG CCCCHHCCCCCCCCC	40.73	23403867
482	Phosphorylation	EQDSGLDGMPGSPPP HHCCCCCCCCCCCCC	29.27	32142685
486	Phosphorylation	GLDGMPGSPPPSQPD CCCCCCCCCCCCCCC	28.50	25159151
490	Phosphorylation	MPGSPPPSQPDPEHL CCCCCCCCCCCHHHC	61.18	23403867
491	Ubiquitination	PGSPPPSQPDPEHLD CCCCCCCCCCHHHCC	52.79	22817900
492	Ubiquitination	GSPPPSQPDPEHLDK CCCCCCCCCHHHCCC	64.56	22817900
494	Ubiquitination	PPPSQPDPEHLDKPK CCCCCCCHHHCCCCC	37.27	22817900
496	Ubiquitination	PSQPDPEHLDKPKLK CCCCCHHHCCCCCCC	44.72	22817900
497	Phosphorylation	SQPDPEHLDKPKLKA CCCCHHHCCCCCCCC	9.62	32142685
497	Ubiquitination	SQPDPEHLDKPKLKA CCCCHHHCCCCCCCC	9.62	22817900
499	Ubiquitination	PDPEHLDKPKLKAGG CCHHHCCCCCCCCCC	50.87	22817900
507	Phosphorylation	PKLKAGGSVESLRSS CCCCCCCCHHHHHHH	23.07	29255136
510	Phosphorylation	KAGGSVESLRSSLSG CCCCCHHHHHHHHCC	27.25	29255136
519	Phosphorylation	RSSLSGQSSMSGQTV HHHHCCCCCCCCCEE	31.37	30576142
520	Phosphorylation	SSLSGQSSMSGQTVS HHHCCCCCCCCCEEE	14.74	28348404
522	Phosphorylation	LSGQSSMSGQTVSTT HCCCCCCCCCEEECC	29.69	28348404
522	Ubiquitination	LSGQSSMSGQTVSTT HCCCCCCCCCEEECC	29.69	22817900
523	Ubiquitination	SGQSSMSGQTVSTTD CCCCCCCCCEEECCC	20.66	22817900
525	Phosphorylation	QSSMSGQTVSTTDSS CCCCCCCEEECCCCC	21.68	27251275
525	Ubiquitination	QSSMSGQTVSTTDSS CCCCCCCEEECCCCC	21.68	22817900
527	Phosphorylation	SMSGQTVSTTDSSTS CCCCCEEECCCCCCC	29.04	30576142
538	Phosphorylation	SSTSNRESVKSEDGD CCCCCCCCCCCCCCC	31.44	30576142
541	Phosphorylation	SNRESVKSEDGDDEE CCCCCCCCCCCCCCC	38.47	28985074
551	Phosphorylation	GDDEEPPYRGPFCGR CCCCCCCCCCCCCCC	38.63	28985074
556	Ubiquitination	PPYRGPFCGRARVHT CCCCCCCCCCEEEEC	3.97	22817900
557	Ubiquitination	PYRGPFCGRARVHTD CCCCCCCCCEEEECC	27.02	22817900
559	Ubiquitination	RGPFCGRARVHTDFT CCCCCCCEEEECCCC	11.79	22817900
563	Phosphorylation	CGRARVHTDFTPSPY CCCEEEECCCCCCCC	29.92	28152594
566	Phosphorylation	ARVHTDFTPSPYDTD EEEECCCCCCCCCCC	26.18	28152594
568	Phosphorylation	VHTDFTPSPYDTDSL EECCCCCCCCCCCCC	32.79	28152594
569	Phosphorylation	HTDFTPSPYDTDSLK ECCCCCCCCCCCCCE	32.02	32142685
570	Phosphorylation	TDFTPSPYDTDSLKL CCCCCCCCCCCCCEE	35.49	30108239
570	Ubiquitination	TDFTPSPYDTDSLKL CCCCCCCCCCCCCEE	35.49	22817900
571	Ubiquitination	DFTPSPYDTDSLKLK CCCCCCCCCCCCEEC	47.63	22817900
572	Phosphorylation	FTPSPYDTDSLKLKK CCCCCCCCCCCEECC	22.96	28152594
573	Ubiquitination	TPSPYDTDSLKLKKG CCCCCCCCCCEECCC	49.42	22817900
574	Phosphorylation	PSPYDTDSLKLKKGD CCCCCCCCCEECCCC	29.51	28152594
578	Ubiquitination	DTDSLKLKKGDIIDI CCCCCEECCCCEEEE	53.79	22817900
579	Ubiquitination	TDSLKLKKGDIIDII CCCCEECCCCEEEEE	72.72	22817900
581	Ubiquitination	SLKLKKGDIIDIISK CCEECCCCEEEEEEC	43.48	22817900
587	Phosphorylation	GDIIDIISKPPMGTW CCEEEEEECCCCCCH	39.17	28258704
597	Phosphorylation	PMGTWMGLLNNKVGT CCCCHHHHHCCCCCE	2.40	32142685
598	Phosphorylation	MGTWMGLLNNKVGTF CCCHHHHHCCCCCEE	5.71	32142685
604	Phosphorylation	LLNNKVGTFKFIYVD HHCCCCCEEEEEEEE	27.00	32142685
609	Phosphorylation	VGTFKFIYVDVLSED CCEEEEEEEEECCCC	8.17	23403867
614	Phosphorylation	FIYVDVLSEDEEKPK EEEEEECCCCCCCCC	42.73	30266825
615	Ubiquitination	IYVDVLSEDEEKPKR EEEEECCCCCCCCCC	66.34	22817900
616	Ubiquitination	YVDVLSEDEEKPKRP EEEECCCCCCCCCCC	67.01	22817900
618	Ubiquitination	DVLSEDEEKPKRPTR EECCCCCCCCCCCCC	83.45	22817900
645	Phosphorylation	VEDLLDRINLKEHMP HHHHHHHCCHHHHCC	7.65	32142685
659	Phosphorylation	PTFLFNGYEDLDTFK CCEECCCCCCHHHHH	13.84	27642862
676	Phosphorylation	EEEDLDELNIRDPEH CHHHHHHCCCCCHHH	6.88	32142685
689	Phosphorylation	EHRAVLLTAVELLQE HHHHHHHHHHHHHHH	25.21	27080861
696	Phosphorylation	TAVELLQEYDSNSDQ HHHHHHHHHCCCCCC	51.80	32142685
697	Phosphorylation	AVELLQEYDSNSDQS HHHHHHHHCCCCCCC	16.23	22496350
699	Phosphorylation	ELLQEYDSNSDQSGS HHHHHHCCCCCCCCC	37.01	29743597
701	Phosphorylation	LQEYDSNSDQSGSQE HHHHCCCCCCCCCCE	40.76	26657352
704	Phosphorylation	YDSNSDQSGSQEKLL HCCCCCCCCCCEEEE	45.46	29743597
706	Phosphorylation	SNSDQSGSQEKLLVD CCCCCCCCCEEEEEC	40.17	30278072
713	Phosphorylation	SQEKLLVDSQGLSGC CCEEEEECCCCCCCC	34.90	32142685
714	Phosphorylation	QEKLLVDSQGLSGCS CEEEEECCCCCCCCC	20.76	23403867
718	Phosphorylation	LVDSQGLSGCSPRDS EECCCCCCCCCCCCC	44.57	29255136
720	Phosphorylation	DSQGLSGCSPRDSGC CCCCCCCCCCCCCCC	4.56	32142685
721	Phosphorylation	SQGLSGCSPRDSGCY CCCCCCCCCCCCCCC	26.88	19664994
725	Phosphorylation	SGCSPRDSGCYESSE CCCCCCCCCCCCCCH	31.85	23403867
728	Phosphorylation	SPRDSGCYESSENLE CCCCCCCCCCCHHCC	23.52	23403867
730	Phosphorylation	RDSGCYESSENLENG CCCCCCCCCHHCCCC	19.24	25849741
731	Phosphorylation	DSGCYESSENLENGK CCCCCCCCHHCCCCC	20.68	23403867
737	Phosphorylation	SSENLENGKTRKASL CCHHCCCCCCCCHHH	24.28	32142685
739	Phosphorylation	ENLENGKTRKASLLS HHCCCCCCCCHHHHH	38.51	29514088
743	Phosphorylation	NGKTRKASLLSAKSS CCCCCCHHHHHCCCC	32.64	23927012
746	Phosphorylation	TRKASLLSAKSSTEP CCCHHHHHCCCCCCC	38.66	23403867
759	Phosphorylation	EPSLKSFSRNQLGNY CCCHHHCCCCCCCCC	37.10	17081983
761	Phosphorylation	SLKSFSRNQLGNYPT CHHHCCCCCCCCCCC	39.98	32142685
766	Phosphorylation	SRNQLGNYPTLPLMK CCCCCCCCCCCCCCC	8.87	21609022
768	Phosphorylation	NQLGNYPTLPLMKSG CCCCCCCCCCCCCCC	30.55	28442448
792	Phosphorylation	GRLGGGLAPDTSKSC CCCCCCCCCCCCCCC	11.82	32142685
812	Phosphorylation	TGLNKNRRSLPVSIC CCCCCCCCCCCHHHH	52.52	32142685
813	Phosphorylation	GLNKNRRSLPVSICR CCCCCCCCCCHHHHC	33.51	19664994
817	Phosphorylation	NRRSLPVSICRSCET CCCCCCHHHHCCCCC	17.65	23403867
821	Phosphorylation	LPVSICRSCETLEGP CCHHHHCCCCCCCCC	16.34	23927012
824	Phosphorylation	SICRSCETLEGPQTV HHHCCCCCCCCCCCC	34.14	23403867
837	Phosphorylation	TVDTWPRSHSLDDLQ CCCCCCCCCCCCCCC	17.22	30278072
839	Phosphorylation	DTWPRSHSLDDLQVE CCCCCCCCCCCCCCC	34.44	30278072
855	Phosphorylation	GAEQDVPTEVTEPPP CCCCCCCCCCCCCCC	42.83	23403867
858	Phosphorylation	QDVPTEVTEPPPQIV CCCCCCCCCCCCCCC	36.22	23403867
901	Phosphorylation	LTQSKRFSEPQKLTT HHCCCCCCCCCCCCC	53.02	24719451
907	Phosphorylation	FSEPQKLTTKKLEGS CCCCCCCCCCCCCCC	43.54	28509920
908	Phosphorylation	SEPQKLTTKKLEGSI CCCCCCCCCCCCCCC	36.30	28509920
920	Methylation	GSIAASGRGLSPPQC CCCCCCCCCCCCCCC	40.14	54559087
923	Phosphorylation	AASGRGLSPPQCLPR CCCCCCCCCCCCCCC	37.04	30266825
927	Phosphorylation	RGLSPPQCLPRNYDA CCCCCCCCCCCCCCC	7.53	32142685
932	Phosphorylation	PQCLPRNYDAQPPGA CCCCCCCCCCCCCCC	17.59	22817900
934	Phosphorylation	CLPRNYDAQPPGAKH CCCCCCCCCCCCCCC	17.27	32142685
946	Phosphorylation	AKHGLARTPLEGHRK CCCCCCCCCCCCCCC	26.98	28555341
975	Phosphorylation	EGVDAEQRMQPKIPS CCCCHHHHHCCCCCC	19.74	32142685
992	Phosphorylation	PPVPAKKSRERLANG CCCCCHHHHHHHHCC	38.37	-
1006	Phosphorylation	GLHPVPMGPSGALPS CCCCCCCCCCCCCCC	13.72	32142685
1013	Phosphorylation	GPSGALPSPDAPCLP CCCCCCCCCCCCCCC	35.94	29978859
1025	Phosphorylation	CLPVKRGSPASPTSP CCCCCCCCCCCCCCH	22.71	25159151
1028	Phosphorylation	VKRGSPASPTSPSDC CCCCCCCCCCCHHCC	31.90	29255136
1030	Phosphorylation	RGSPASPTSPSDCPP CCCCCCCCCHHCCCC	51.26	29255136
1031	Phosphorylation	GSPASPTSPSDCPPA CCCCCCCCHHCCCCC	26.28	29255136
1033	Phosphorylation	PASPTSPSDCPPALA CCCCCCHHCCCCCCC	52.17	28450419
1045	Phosphorylation	ALAPRPLSGQAPGSP CCCCCCCCCCCCCCC	31.38	22167270
1051	Phosphorylation	LSGQAPGSPPSTRPP CCCCCCCCCCCCCCC	32.36	29255136
1054	Phosphorylation	QAPGSPPSTRPPPWL CCCCCCCCCCCCCCH	40.19	29255136
1055	Phosphorylation	APGSPPSTRPPPWLS CCCCCCCCCCCCCHH	53.63	29255136
1062	Phosphorylation	TRPPPWLSELPENTS CCCCCCHHCCCCCCC	32.97	25850435
1068	Phosphorylation	LSELPENTSLQEHGV HHCCCCCCCHHHHCC	29.20	25002506
1069	Phosphorylation	SELPENTSLQEHGVK HCCCCCCCHHHHCCC	39.37	23312004
1086	Phosphorylation	PALTRKVSCARGVDL HHHHHHHHHCCCCCH	12.70	-
1233	Phosphorylation	RHIRKLLSAARLFKL HHHHHHHHHHHHCCC	30.25	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
407	S	Phosphorylation	Kinase	LATS1	O95835	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SASH1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SASH1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SUV92_HUMAN	SUV39H2	physical	20084102

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SASH1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-90, AND MASSSPECTROMETRY.	17081983 [Abstract]