KBP_HUMAN - dbPTM
KBP_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KBP_HUMAN
UniProt AC Q96EK5
Protein Name KIF1-binding protein {ECO:0000305|PubMed:16225668}
Gene Name KIF1BP {ECO:0000312|HGNC:HGNC:23419}
Organism Homo sapiens (Human).
Sequence Length 621
Subcellular Localization Cytoplasm, cytoskeleton .
Protein Description Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development..
Protein Sequence MANVPWAEVCEKFQAALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPEAEDGPGAGDHALGLPAEVVEPEGPVAQRAVRLAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRRYRLSHDCISLCIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEVGSPPLDPTERFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHLEMFEKAAHYCHSTLKRQLEHNAYHPIEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
20PhosphorylationFQAALALSRVELHKN
HHHHHHHHCCCCCCC		28.7724719451
26UbiquitinationLSRVELHKNPEKEPY
HHCCCCCCCCCCCCC		83.3624816145
30UbiquitinationELHKNPEKEPYKSKY
CCCCCCCCCCCCCHH		66.31-
37PhosphorylationKEPYKSKYSARALLE
CCCCCCHHHHHHHHH		18.0422817900
84UbiquitinationPAEVVEPEGPVAQRA
CCEEECCCCHHHHHH		63.7224816145
178PhosphorylationQYMKEVGSPPLDPTE
HHHHHHCCCCCCHHH		28.6425159151
184PhosphorylationGSPPLDPTERFLPEE
CCCCCCHHHCCCCHH		39.1928985074
193UbiquitinationRFLPEEEKLTEQERS
CCCCHHHHCCHHHHH		65.0824816145
236UbiquitinationHYCHSTLKRQLEHNA
HHHHHHHHHHHHHCC		37.8829967540
267SulfoxidationYINKLCFMEARHCLS
HHHHHHHHHHHHHHH		3.7221406390
281UbiquitinationSAANVIFGQTGKISA
HHHHHHHCCCCCEEC		17.0221890473
287PhosphorylationFGQTGKISATEDTPE
HCCCCCEECCCCCCC		32.4026270265
289PhosphorylationQTGKISATEDTPEAE
CCCCEECCCCCCCCC		27.8326714015
292PhosphorylationKISATEDTPEAEGEV
CEECCCCCCCCCCCC		19.4525159151
297UbiquitinationEDTPEAEGEVPELYH
CCCCCCCCCCCCHHH		48.5322817900
298UbiquitinationDTPEAEGEVPELYHQ
CCCCCCCCCCCHHHH		46.5421890473
307UbiquitinationPELYHQRKGEIARCW
CCHHHHCCHHHHHHH		55.0929967540
349UbiquitinationSELRALRKKELDEEE
HHHHHHHHHCCCHHH		51.9930230243
350UbiquitinationELRALRKKELDEEES
HHHHHHHHCCCHHHH		58.0124816145
357PhosphorylationKELDEEESIRKKAVQ
HCCCHHHHHHHHHHH		30.8520873877
361UbiquitinationEEESIRKKAVQFGTG
HHHHHHHHHHHHCCH		43.8929967540
371GlutathionylationQFGTGELCDAISAVE
HHCCHHHHHHHHHHH		2.6422555962
494MethylationLKVAIADRLRDPDSH
HHHHHHHHCCCCCCH		23.7054390929
496MethylationVAIADRLRDPDSHIV
HHHHHHCCCCCCHHH		55.07115481167
500PhosphorylationDRLRDPDSHIVKKIN
HHCCCCCCHHHHHHH		22.0923403867
504UbiquitinationDPDSHIVKKINNLNK
CCCCHHHHHHHCCCH		47.5429967540
505UbiquitinationPDSHIVKKINNLNKS
CCCHHHHHHHCCCHH		39.5129967540
511UbiquitinationKKINNLNKSALKYYQ
HHHHCCCHHHHHHHH		40.0329967540
516PhosphorylationLNKSALKYYQLFLDS
CCHHHHHHHHHHHHH		9.4120068231
547UbiquitinationLRPAMLAKFRVARLY
HHHHHHHHHHHHHHH		29.7322817900
556UbiquitinationRVARLYGKIITADPK
HHHHHHCCEECCCCH		19.8533845483
556AcetylationRVARLYGKIITADPK
HHHHHHCCEECCCCH		19.8527452117
559PhosphorylationRLYGKIITADPKKEL
HHHCCEECCCCHHHH		28.6025599653
563UbiquitinationKIITADPKKELENLA
CEECCCCHHHHHHHH		60.4722817900
563AcetylationKIITADPKKELENLA
CEECCCCHHHHHHHH		60.4720167786
564UbiquitinationIITADPKKELENLAT
EECCCCHHHHHHHHH		73.2922817900
564AcetylationIITADPKKELENLAT
EECCCCHHHHHHHHH		73.2920167786
610UbiquitinationMVSLLPTKMERFRTK
HHHHCCHHHHHHHHH		36.5032015554
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KBP_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KBP_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KBP_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CEP76_HUMANCEP76physical
16189514
ZN638_HUMANZNF638physical
16189514
ZN670_HUMANZNF670physical
16189514
PKHF1_HUMANPLEKHF1physical
16189514
AN32B_HUMANANP32Bphysical
22863883
NIF3L_HUMANNIF3L1physical
22863883
SH3G1_HUMANSH3GL1physical
22863883
KI18A_HUMANKIF18Aphysical
28514442
KI16B_HUMANKIF16Bphysical
28514442
KIF15_HUMANKIF15physical
28514442
KIF3A_HUMANKIF3Aphysical
28514442
KI13A_HUMANKIF13Aphysical
28514442
KI18B_HUMANKIF18Bphysical
28514442
KIF1A_HUMANKIF1Aphysical
28514442
KIF14_HUMANKIF14physical
28514442
KIF1B_HUMANKIF1Bphysical
28514442
KIF3C_HUMANKIF3Cphysical
28514442
KI13B_HUMANKIF13Bphysical
28514442
KIF3B_HUMANKIF3Bphysical
28514442
KIF1C_HUMANKIF1Cphysical
28514442
STAR9_HUMANSTARD9physical
28514442
KIF3A_HUMANKIF3Aphysical
27173435
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
609460Goldberg-Shprintzen syndrome (GOSHS)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KBP_HUMAN

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Related Literatures of Post-Translational Modification

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