D39U1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: D39U1_HUMAN
• UniProt AC: Q9NRG7
• Protein Name: Epimerase family protein SDR39U1 {ECO:0000305}
• Gene Name: SDR39U1
• Organism: Homo sapiens (Human).
• Sequence Length: 319
• Protein Description: Putative NADP-dependent oxidoreductase..
• Protein Sequence: MGWRRKRVPQRGRKAPPPQLHGNINNLYFPIRWRDRLHWDSPNPAAECQRHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVIGSRLETTQLLAKAITKAPQPPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPFRLGLGGPIGSGHQFFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALGRRAFIPLPSAVVQAVFGRQRAIMLLEGQKVIPQRTLATGYQYSFPELGAALKEIVA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9 (in isoform 2)	Phosphorylation	-	23.37	24719451
17 (in isoform 2)	Phosphorylation	-	33.84	24719451
31 (in isoform 2)	Phosphorylation	-	4.77	24719451
66	Phosphorylation	KPGPGRITWDELAAS CCCCCCCCHHHHHHC	26.04	-
73	Phosphorylation	TWDELAASGLPSCDA CHHHHHHCCCCCCCH	34.94	-
76 (in isoform 2)	Ubiquitination	-	36.12	21890473
76	Ubiquitination	ELAASGLPSCDAAVN HHHHCCCCCCCHHHH	36.12	-
85	Phosphorylation	CDAAVNLAGENILNP CCHHHHHCCCCCCHH	20.32	20068231
91	Ubiquitination	LAGENILNPLRRWNE HCCCCCCHHHHHHHH	29.75	-
95	Ubiquitination	NILNPLRRWNETFQK CCCHHHHHHHHHHHH	48.53	-
99	Phosphorylation	PLRRWNETFQKEVIG HHHHHHHHHHHHHHH	28.31	-
102	Ubiquitination	RWNETFQKEVIGSRL HHHHHHHHHHHHHHH	50.16	2189047
102	Acetylation	RWNETFQKEVIGSRL HHHHHHHHHHHHHHH	50.16	25038526
102 (in isoform 1)	Ubiquitination	-	50.16	21890473
111	Phosphorylation	VIGSRLETTQLLAKA HHHHHHHHHHHHHHH	25.16	20068231
112	Phosphorylation	IGSRLETTQLLAKAI HHHHHHHHHHHHHHH	14.08	20068231
117	Malonylation	ETTQLLAKAITKAPQ HHHHHHHHHHHCCCC	40.05	26320211
286	Sulfoxidation	FGRQRAIMLLEGQKV HCCHHEEHHHCCCEE	3.22	21406390
315	Acetylation	PELGAALKEIVA--- HHHHHHHHHHHC---	40.44	7367795

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of D39U1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of D39U1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of D39U1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of D39U1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.