T120A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T120A_HUMAN
• UniProt AC: Q9BXJ8
• Protein Name: Transmembrane protein 120A
• Gene Name: TMEM120A
• Organism: Homo sapiens (Human).
• Sequence Length: 343
• Subcellular Localization: Nucleus inner membrane ; Multi-pass membrane protein .
• Protein Description: Necessary for efficient adipogenesis. [PubMed: 26024229]
• Protein Sequence: MQPPPPGPLGDCLRDWEDLQQDFQNIQETHRLYRLKLEELTKLQNNCTSSITRQKKRLQELALALKKCKPSLPAEAEGAAQELENQMKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILILISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLAQDPQCKEWQVLMCGFPFLLLFLGNFFTTLRVVHHKFHSQRHGSKKD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	Acetylation	THRLYRLKLEELTKL HHHHHHHHHHHHHHH	44.87	25953088

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T120A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T120A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T120A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SNP29_HUMAN	SNAP29	physical	26186194
NCLN_HUMAN	NCLN	physical	27173435
T120B_HUMAN	TMEM120B	physical	27173435
SERC1_HUMAN	SERINC1	physical	27173435
METL9_HUMAN	METTL9	physical	27173435
NOMO1_HUMAN	NOMO1	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.