METL9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: METL9_HUMAN
• UniProt AC: Q9H1A3
• Protein Name: Methyltransferase-like protein 9
• Gene Name: METTL9
• Organism: Homo sapiens (Human).
• Sequence Length: 318
• Protein Sequence: MRLLAGWLCLSLASVWLARRMWTLRSPLTRSLYVNMTSGPGGPAAAAGGRKENHQWYVCNREKLCESLQAVFVQSYLDQGTQIFLNNSIEKSGWLFIQLYHSFVSSVFSLFMSRTSINGLLGRGSMFVFSPDQFQRLLKINPDWKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKKKYRVLGINEWQNTGFQYDVISCLNLLDRCDQPLTLLKDIRSVLEPTRGRVILALVLPFHPYVENVGGKWEKPSEILEIKGQNWEEQVNSLPEVFRKAGFVIEAFTRLPYLCEGDMYNDYYVLDDAVFVLKPV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	WLARRMWTLRSPLTR HHHHHHHHCCCCCCC	11.71	26270265
26	Phosphorylation	RRMWTLRSPLTRSLY HHHHHCCCCCCCEEE	27.63	29496963
29	Phosphorylation	WTLRSPLTRSLYVNM HHCCCCCCCEEEEEC	22.92	30278072
31	Phosphorylation	LRSPLTRSLYVNMTS CCCCCCCEEEEECCC	20.86	28857561
35	N-linked_Glycosylation	LTRSLYVNMTSGPGG CCCEEEEECCCCCCC	17.92	UniProtKB CARBOHYD
37	Phosphorylation	RSLYVNMTSGPGGPA CEEEEECCCCCCCCC	25.90	-
51	Ubiquitination	AAAAGGRKENHQWYV CCCCCCCCCCCEEEE	67.17	29967540
92	Phosphorylation	LNNSIEKSGWLFIQL ECCCHHHCCCHHHHH	23.55	28857561
98	Ubiquitination	KSGWLFIQLYHSFVS HCCCHHHHHHHHHHH	28.74	21963094
102	Phosphorylation	LFIQLYHSFVSSVFS HHHHHHHHHHHHHHH	17.49	28857561
105	Ubiquitination	QLYHSFVSSVFSLFM HHHHHHHHHHHHHHH	20.83	29967540
105	Phosphorylation	QLYHSFVSSVFSLFM HHHHHHHHHHHHHHH	20.83	28857561
106	Phosphorylation	LYHSFVSSVFSLFMS HHHHHHHHHHHHHHC	23.14	28857561
115	Phosphorylation	FSLFMSRTSINGLLG HHHHHCCCCCCCCCC	27.01	24114839
139	Ubiquitination	DQFQRLLKINPDWKT HHHHHHHCCCCCCCH	45.06	-
145	Ubiquitination	LKINPDWKTHRLLDL HCCCCCCCHHEEEEC	41.66	29967540
183	Ubiquitination	SETMIWQLQKKKYRV CHHHHHHHHHCCEEE	4.91	21963094
217	Ubiquitination	NLLDRCDQPLTLLKD HHHHHCCCCHHHHHH	38.23	29967540
223	Ubiquitination	DQPLTLLKDIRSVLE CCCHHHHHHHHHHHC	54.97	21963094
225	Ubiquitination	PLTLLKDIRSVLEPT CHHHHHHHHHHHCCC	3.19	29967540
257	Ubiquitination	NVGGKWEKPSEILEI CCCCCCCCCHHHEEE	53.37	29967540
265	Ubiquitination	PSEILEIKGQNWEEQ CHHHEEECCCCHHHH	45.10	29967540
282	Ubiquitination	SLPEVFRKAGFVIEA CHHHHHHHCCHHHHH	41.20	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of METL9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of METL9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of METL9_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of METL9_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.