T120B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T120B_HUMAN
• UniProt AC: A0PK00
• Protein Name: Transmembrane protein 120B
• Gene Name: TMEM120B
• Organism: Homo sapiens (Human).
• Sequence Length: 339
• Subcellular Localization: Nucleus inner membrane ; Multi-pass membrane protein .
• Protein Description: Necessary for efficient adipogenesis..
• Protein Sequence: MSGQLERCEREWHELEGEFQELQETHRIYKQKLEELAALQTLCSSSISKQKKHLKDLKLTLQRCKRHASREEAELVQQMAANIKERQDVFFDMEAYLPKKNGLYLNLVLGNVNVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAVACRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPNGPIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLFCGHFWQLYNAVTLFELSSHEECREWQVFVLAFTFLILFLGNFLTTLKVVHAKLQKNRGKTKQP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
58	Malonylation	KKHLKDLKLTLQRCK HHHHHHHHHHHHHHH	49.94	26320211
60	Phosphorylation	HLKDLKLTLQRCKRH HHHHHHHHHHHHHHH	21.18	-
69	Phosphorylation	QRCKRHASREEAELV HHHHHHHCHHHHHHH	33.81	30108239
328	Ubiquitination	TLKVVHAKLQKNRGK HHHHHHHHHHHCCCC	36.25	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T120B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T120B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T120B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NCLN_HUMAN	NCLN	physical	27173435
SERC1_HUMAN	SERINC1	physical	27173435
METL9_HUMAN	METTL9	physical	27173435
NOMO1_HUMAN	NOMO1	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.