| UniProt ID | VSTM4_HUMAN | |
|---|---|---|
| UniProt AC | Q8IW00 | |
| Protein Name | V-set and transmembrane domain-containing protein 4 | |
| Gene Name | VSTM4 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 320 | |
| Subcellular Localization |
Peptide Lv: Secreted . Cell membrane Single-pass type I membrane protein . |
|
| Protein Description | Peptide Lv enhances L-type voltage-gated calcium channel (L-VGCC) currents in retinal photoreceptors.. | |
| Protein Sequence | MRLLALAAAALLARAPAPEVCAALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGSSATEMRVISLKASEESSFEKTKETWAFFEDLYVYAVLVCCVGILSILLFMLVIVWQSVFNKRKSRVRHYLVKCPQNSSGETVTSVTSLAPLQPKKGKRQKEKPDIPPAVPAKAPIAPTFHKPKLLKPQRKVTLPKIAEENLTYAELELIKPHRAAKGAPTSTVYAQILFEENKL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 25 | N-linked_Glycosylation | PEVCAALNVTVSPGP HHHHHCCCCEEECCC | 23.76 | UniProtKB CARBOHYD | |
| 41 | N-linked_Glycosylation | VDYLEGENATLLCHV CHHCCCCCEEEEEEH | 49.43 | UniProtKB CARBOHYD | |
| 79 | Phosphorylation | EALMVKMTKLRVVQY HHHHHHHHHHEEEEH | 22.62 | - | |
| 89 | N-linked_Glycosylation | RVVQYYGNFSRSAKR EEEEHHCCCCHHHHH | 18.65 | UniProtKB CARBOHYD | |
| 125 | Phosphorylation | QPSDQGHYVCRVQEI CCCCCCEEEEEEEEE | 14.20 | - | |
| 143 | Phosphorylation | RNKWTAWSNGSSATE CCCEEECCCCCCCCE | 28.93 | 29083192 | |
| 144 | N-linked_Glycosylation | NKWTAWSNGSSATEM CCEEECCCCCCCCEE | 43.60 | UniProtKB CARBOHYD | |
| 146 | Phosphorylation | WTAWSNGSSATEMRV EEECCCCCCCCEEEE | 22.50 | 29083192 | |
| 147 | Phosphorylation | TAWSNGSSATEMRVI EECCCCCCCCEEEEE | 40.38 | 29083192 | |
| 149 | Phosphorylation | WSNGSSATEMRVISL CCCCCCCCEEEEEEE | 32.06 | 29083192 | |
| 155 | Phosphorylation | ATEMRVISLKASEES CCEEEEEEEECCCCC | 22.44 | 24719451 | |
| 223 | Phosphorylation | LVKCPQNSSGETVTS EEECCCCCCCCEEEE | 34.18 | 24719451 | |
| 232 | Phosphorylation | GETVTSVTSLAPLQP CCEEEEEEEECCCCC | 20.14 | - | |
| 278 | Phosphorylation | LKPQRKVTLPKIAEE CCCCCCCCHHHHHHH | 40.14 | 23312004 | |
| 288 | Phosphorylation | KIAEENLTYAELELI HHHHHCCCHHHHEEC | 32.06 | 25884760 | |
| 289 | Phosphorylation | IAEENLTYAELELIK HHHHCCCHHHHEECC | 10.97 | 25884760 | |
| 310 | Phosphorylation | GAPTSTVYAQILFEE CCCCCCHHHHHHHHH | 7.90 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VSTM4_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VSTM4_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VSTM4_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of VSTM4_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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